Esther Bullitt | Profiles RNS

Esther Bullitt, PhD Hear my name

Professor

Boston University Chobanian & Avedisian School of Medicine

Pharmacology, Physiology & Biophysics

PhD, Brandeis University
AB, Grinnell College

Pronouns: she/her/hers

Websites

	Pharmacology, Physiology & Biophysics Faculty
	Bullitt Laboratory

ORCID : 0000-0003-2447-6209

Structural studies of biological macromolecular assemblies are providing an understanding of cellular function. In our laboratory, we utilize electron microscopy and image reconstruction to investigate questions about microbial virulence.

Work in the lab currently focuses on bacterial adhesion pili (fimbriae), type III secretion system needles, and virus replication. These projects address basic medical research questions directed at understanding bacterial adhesion to human host tissue and viral replication. Our data support development of novel therapeutics targeting these important health issues including, for example, development of a vaccine against traveler’s diarrhea.

Diversity, Equity, Inclusion and Accessibility

The privilege afforded me to be able to work as I decide factors into decisions I have made throughout my career. I choose fostering the careers of others as a critical goal, working to create an inclusive scientific environment. As president of the Microscopy Society of America in 2020, I created a policy and a task force for diversity, equity, and inclusion. The need for this initiative was built on my experience over the past 20 years of advocating for and training scientists from under-represented groups. My current work represents another aspect of my deepened commitment to the 'democratization' of scientific research. To support and advance the design of novel strategies to confront health care challenges posed by emerging pathogens, I am working with the Graduate Medical Sciences DEI Steering Committee to diversify our workforce and make all scientists feel that their contributions are recognized and appreciated.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

BU Research
NIH RePORTER Research

Tundra Cryo-EM for Boston University
03/15/2023 - 03/14/2025 (PI)
NIH/Office of the Director
1S10OD032253-01A1

Exploiting the Salivary Arsenal to Inhibit Diarrheal Disease
02/22/2021 - 01/31/2025 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI156236-02

The multiple states of IpaB Shigella type lll secretion
06/02/2014 - 11/30/2018 (Subcontract PI)
University of Kansas NIH NIAID
5R01AI099489-06

Towards the Disruption of Viral RNA Replication
07/01/2012 - 06/30/2017 (PI)
NIH/National Institute of General Medical Sciences
5R01GM102474-04

Measurement of Bacteriophage Lengths using Transmission electron microscopy and image analysis
01/01/2012 - 12/31/2016 (PI)
Neurophage pharmaceuticals, Inc.

Towards the Disruption of Viral RNA Replication
07/01/2012 - 06/30/2016 (PI)
NIH/National Institute of General Medical Sciences
1R01GM102474-01

The multiple states of IpaB Shigella type III secretion
12/04/2012 - 06/01/2014 (Subcontract PI)
University of Oklahoma NIH NIAID
1R01AI099489-01A1

Title

Yr	Title	Project-Sub Proj	Pubs
2023	Tundra Cryo-EM for Boston University	1S10OD032253-01A1
2022	Exploiting the Salivary Arsenal to Inhibit Diarrheal Disease	5R21AI156236-02
2021	Exploiting the Salivary Arsenal to Inhibit Diarrheal Disease	1R21AI156236-01
2021	Midwest Consortium for High Resolution Cryoelectron Microscopy	5U24GM116789-05	3
2020	CryoEM Data Collection Facility Consortium at NCM	5U24GM116787-05	6
2020	Midwest Consortium for High Resolution Cryoelectron Microscopy	5U24GM116789-04	3
2020	The Southeastern Consortium for Microscopy of MacroMolecular Machines	5U24GM116788-05	7
2019	CryoEM Data Collection Facility Consortium at NCM	5U24GM116787-04	6
2019	Midwest Consortium for High Resolution Cryoelectron Microscopy	5U24GM116789-03	3
2019	The Southeastern Consortium for Microscopy of MacroMolecular Machines	5U24GM116788-04	7

Showing 10 of 40 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Gagnon KA, Huang J, Hix OT, Hui VW, Hinds A, Bullitt E, Eyckmans J, Kotton DN, Chen CS. Multicompartment duct platform to study epithelial-endothelial crosstalk associated with lung adenocarcinoma. APL Bioeng. 2024 Jun; 8(2):026126.View Related Profiles.

Chen, Christopher
Kotton, Darrell
Bullitt, Esther
Eyckmans, Jeroen

PMID: 38911024; PMCID: PMC11191334; DOI: 10.1063/5.0207228;

Jayaraman S, Urdaneta A, Bullitt E, Fändrich M, Gursky O. Lipid clearance and amyloid formation by serum amyloid A: exploring the links between beneficial and pathologic actions of an enigmatic protein. J Lipid Res. 2023 Sep; 64(9):100429.View Related Profiles.

Bullitt, Esther
Gursky, Olga
Jayaraman, Shobini

PMID: 37604227; PMCID: PMC10509712; DOI: 10.1016/j.jlr.2023.100429;

Thairatana S, Doran M, Sonani RR, Egelman EH, Bullitt E. New Morphologies of Hib Adhesion Pili. Microsc Microanal. 2023 Jul 22; 29(29 Suppl 1):937. PMID: 37613394

Klimtchuk ES, Peterle D, Bullitt E, Connors LH, Engen JR, Gursky O. Role of complementarity-determining regions 1 and 3 in pathologic amyloid formation by human immunoglobulin ?1 light chains. Amyloid. 2023 Dec; 30(4):364-378.View Related Profiles.

Klimtchuk, Elena
Bullitt, Esther
Connors, Lawreen
Gursky, Olga

PMID: 37216473; PMCID: PMC10663386; DOI: 10.1080/13506129.2023.2212397;

Doran MH, Baker JL, Dahlberg T, Andersson M, Bullitt E. Three structural solutions for bacterial adhesion pilus stability and superelasticity. Structure. 2023 May 04; 31(5):529-540.e7. PMID: 37001523; PMCID: PMC10164138; DOI: 10.1016/j.str.2023.03.005;

Doran MH, Rynkiewicz MJ, Rassici D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W. Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. J Gen Physiol. 2023 Mar 06; 155(3).View Related Profiles.

Bullitt, Esther
Moore, Jeffrey
Rynkiewicz, Michael

PMID: 36633586; PMCID: PMC9859928; DOI: 10.1085/jgp.202213267;

Kaserman JE, Werder RB, Wang F, Matte T, Higgins MI, Dodge M, Lindstrom-Vautrin J, Bawa P, Hinds A, Bullitt E, Caballero IS, Shi X, Gerszten RE, Brunetti-Pierri N, Liesa M, Villacorta-Martin C, Hollenberg AN, Kotton DN, Wilson AA. Human iPSC-hepatocyte modeling of alpha-1 antitrypsin heterozygosity reveals metabolic dysregulation and cellular heterogeneity. Cell Rep. 2022 Dec 06; 41(10):111775.View Related Profiles.

Wilson, Andrew
Hollenberg, Anthony
Kotton, Darrell
Bullitt, Esther
Kaserman, Joseph
Werder, Rhiannon Bree
Matte, Taylor

PMID: 36476855; PMCID: PMC9780780; DOI: 10.1016/j.celrep.2022.111775;

Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W. Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. J Gen Physiol. 2023 Feb 06; 155(2).View Related Profiles.

Bullitt, Esther
Moore, Jeffrey
Rynkiewicz, Michael

PMID: 36459134; PMCID: PMC9723511; DOI: 10.1085/jgp.202213274;

Werder RB, Liu T, Abo KM, Lindstrom-Vautrin J, Villacorta-Martin C, Huang J, Hinds A, Boyer N, Bullitt E, Liesa M, Silverman EK, Kotton DN, Cho MH, Zhou X, Wilson AA. CRISPR interference interrogation of COPD GWAS genes reveals the functional significance of desmoplakin in iPSC-derived alveolar epithelial cells. Sci Adv. 2022 Jul 15; 8(28):eabo6566.View Related Profiles.

Wilson, Andrew
Kotton, Darrell
Bullitt, Esther
Huang, Jessie
Werder, Rhiannon Bree

PMID: 35857525; PMCID: PMC9278866; DOI: 10.1126/sciadv.abo6566;

Hume AJ, Heiden B, Olejnik J, Suder EL, Ross S, Scoon WA, Bullitt E, Ericsson M, White MR, Turcinovic J, Thao TTN, Hekman RM, Kaserman JE, Huang J, Alysandratos KD, Toth GE, Jakab F, Kotton DN, Wilson AA, Emili A, Thiel V, Connor JH, Kemenesi G, Cifuentes D, Mühlberger E. Correction: Recombinant Lloviu virus as a tool to study viral replication and host responses. PLoS Pathog. 2022 Jun; 18(6):e1010659.View Related Profiles.

Hume, Adam
Wilson, Andrew
Emili, Andrew
Cifuentes, Daniel
Kotton, Darrell
Muhlberger, Elke
Bullitt, Esther
Connor, John
Kaserman, Joseph
Olejnik, Judith

PMID: 35749346; PMCID: PMC9231773; DOI: 10.1371/journal.ppat.1010659;

Showing 10 of 74 results. Show More

Dahlberg T, Baker JL, Bullitt E, Andersson M. Unveiling molecular interactions that stabilize bacterial adhesion pili. Biophys J. 2022 Jun 07; 121(11):2096-2106. PMID: 35491503; PMCID: PMC9247471; DOI: 10.1016/j.bpj.2022.04.036;

Kenney DJ, O'Connell AK, Turcinovic J, Montanaro P, Hekman RM, Tamura T, Berneshawi AR, Cafiero TR, Al Abdullatif S, Blum B, Goldstein SI, Heller BL, Gertje HP, Bullitt E, Trachtenberg AJ, Chavez E, Nono ET, Morrison C, Tseng AE, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber BR, Saeed M, Balazs AB, Francis KP, Klose A, Paragas N, Campbell JD, Connor JH, Emili A, Crossland NA, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022 Apr 19; 39(3):110714.View Related Profiles.

Emili, Andrew
Blum, Benjamin
Huber, Bertrand
Bullitt, Esther
Douam, Florian
Connor, John
Campbell, Joshua
Bosmann, Markus
Saeed, Mohsan
Crossland, Nicholas

PMID: 35421379; PMCID: PMC8977517; DOI: 10.1016/j.celrep.2022.110714;

Abo KM, Sainz de Aja J, Lindstrom-Vautrin J, Alysandratos KD, Richards A, Garcia-de-Alba C, Huang J, Hix OT, Werder RB, Bullitt E, Hinds A, Falconer I, Villacorta-Martin C, Jaenisch R, Kim CF, Kotton DN, Wilson AA. Air-liquid interface culture promotes maturation and allows environmental exposure of pluripotent stem cell-derived alveolar epithelium. JCI Insight. 2022 Mar 22; 7(6).View Related Profiles.

Wilson, Andrew
Kotton, Darrell
Bullitt, Esther
Huang, Jessie
Werder, Rhiannon Bree

PMID: 35315362; PMCID: PMC8986076; DOI: 10.1172/jci.insight.155589;

Hume AJ, Heiden B, Olejnik J, Suder EL, Ross S, Scoon WA, Bullitt E, Ericsson M, White MR, Turcinovic J, Thao TTN, Hekman RM, Kaserman JE, Huang J, Alysandratos KD, Toth GE, Jakab F, Kotton DN, Wilson AA, Emili A, Thiel V, Connor JH, Kemenesi G, Cifuentes D, Mühlberger E. Recombinant Lloviu virus as a tool to study viral replication and host responses. PLoS Pathog. 2022 02; 18(2):e1010268.View Related Profiles.

Hume, Adam
Wilson, Andrew
Emili, Andrew
Cifuentes, Daniel
Kotton, Darrell
Muhlberger, Elke
Bullitt, Esther
Huang, Jessie
Connor, John
Kaserman, Joseph
Olejnik, Judith

PMID: 35120176; PMCID: PMC8849519; DOI: 10.1371/journal.ppat.1010268;

Gao Z, Zhang X, Zhang L, Wu S, Ma J, Wang F, Zhou Y, Dai X, Bullitt E, Du Y, Guo JT, Chang J. A yellow fever virus NS4B inhibitor not only suppresses viral replication, but also enhances the virus activation of RIG-I-like receptor-mediated innate immune response. PLoS Pathog. 2022 01; 18(1):e1010271. PMID: 35061864; PMCID: PMC8809586; DOI: 10.1371/journal.ppat.1010271;

Wang R, Hume AJ, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Le Suer J, Huang J, Olejnik J, Villacorta-Martin C, Bullitt E, Hinds A, Ghaedi M, Rollins S, Werder RB, Abo KM, Wilson AA, Mühlberger E, Kotton DN, Hawkins FJ. Human airway lineages derived from pluripotent stem cells reveal the epithelial responses to SARS-CoV-2 infection. Am J Physiol Lung Cell Mol Physiol. 2022 03 01; 322(3):L462-L478.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Bullitt, Esther
Hawkins, Finn
Huang, Jessie
Olejnik, Judith
Werder, Rhiannon Bree

PMID: 35020534; PMCID: PMC8917936; DOI: 10.1152/ajplung.00397.2021;

Hu K, Perez-Matos MC, Argemi J, Vilar-Gomez E, Shalaurova I, Bullitt E, Landeen L, Sugahara G, Deng H, Mathur K, Tran S, Cai H, He H, Yalcin Y, Vieira Barbosa J, Ventura-Cots M, Marx K, Gad AP, Niezen S, Izunza Barba S, Ang LH, Popov YV, Fricker Z, Lai M, Curry M, Afdhal N, Szabo G, Mukamal KJ, Sanyal AJ, Otvos JD, Malik R, Saito T, Connelly MA, Chalasani NP, Bataller R, Jiang ZG. Lipoprotein Z, a hepatotoxic lipoprotein, predicts outcome in alcohol-associated hepatitis. Hepatology. 2022 04; 75(4):968-982.View Related Profiles.

Bullitt, Esther
Fricker, Zachary

PMID: 34662439; PMCID: PMC9299888; DOI: 10.1002/hep.32203;

Baker JL, Dahlberg T, Bullitt E, Andersson M. Impact of an alpha helix and a cysteine-cysteine disulfide bond on the resistance of bacterial adhesion pili to stress. Proc Natl Acad Sci U S A. 2021 05 25; 118(21). PMID: 34011607; PMCID: PMC8166124; DOI: 10.1073/pnas.2023595118;

Mithal A, Hume AJ, Lindstrom-Vautrin J, Villacorta-Martin C, Olejnik J, Bullitt E, Hinds A, Mühlberger E, Mostoslavsky G. Human Pluripotent Stem Cell-Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response. Stem Cell Reports. 2021 04 13; 16(4):940-953.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Bullitt, Esther
Mostoslavsky, Gustavo
Olejnik, Judith

PMID: 33852884; PMCID: PMC8042780; DOI: 10.1016/j.stemcr.2021.02.019;

Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2021 Jan 07; 81(1):212.View Related Profiles. PMID: 33417854; PMCID: PMC7831449; DOI: 10.1016/j.molcel.2020.12.028;

Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2020 12 17; 80(6):1104-1122.e9.View Related Profiles. PMID: 33259812; PMCID: PMC7674017; DOI: 10.1016/j.molcel.2020.11.028;

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 12 03; 27(6):962-973.e7.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Burks, Eric
Bullitt, Esther
Hawkins, Finn
Huang, Jessie
Olejnik, Judith
Bosmann, Markus
Saeed, Mohsan
Werder, Rhiannon Bree

PMID: 32979316; PMCID: PMC7500949; DOI: 10.1016/j.stem.2020.09.013;

Doran MH, Pavadai E, Rynkiewicz MJ, Walklate J, Bullitt E, Moore JR, Regnier M, Geeves MA, Lehman W. Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. Biophys J. 2020 08 18; 119(4):821-830.View Related Profiles.

Bullitt, Esther
Moore, Jeffrey
Rynkiewicz, Michael
Lehman, William

PMID: 32730789; PMCID: PMC7451941; DOI: 10.1016/j.bpj.2020.07.006;

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Burks, Eric
Bullitt, Esther
Hawkins, Finn
Olejnik, Judith
Bosmann, Markus
Saeed, Mohsan
Werder, Rhiannon Bree

PMID: 32637964; PMCID: PMC7337394; DOI: 10.1101/2020.06.30.175695;

Yang JE, Rossignol ED, Chang D, Zaia J, Forrester I, Raja K, Winbigler H, Nicastro D, Jackson WT, Bullitt E. Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus. Sci Rep. 2020 05 14; 10(1):7939.View Related Profiles.

Bullitt, Esther
Rossignol, Evan
Yang, Jie
Zaia, Joseph

PMID: 32409751; PMCID: PMC7224179; DOI: 10.1038/s41598-020-64531-1;

Zheng W, Andersson M, Mortezaei N, Bullitt E, Egelman E. Cryo-EM structure of the CFA/I pilus rod. IUCrJ. 2019 Sep 01; 6(Pt 5):815-821. PMID: 31576215; PMCID: PMC6760452; DOI: 10.1107/S2052252519007966;

Filman DJ, Marino SF, Ward JE, Yang L, Mester Z, Bullitt E, Lovley DR, Strauss M. Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire. Commun Biol. 2019 Jun 19; 2(1):219. PMID: 31925024

Jie E. Yang, Evan D. Rossignol, Deborah Chang, Joseph Zaia, Isaac Forrester, Holly Saulsbery, Daniela Nicastro, William T. Jackson, Esther Bullitt. Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virus. bioRxiv. 2019. View Publication

Brown JW, Badahdah A, Iticovici M, Vickers TJ, Alvarado DM, Helmerhorst EJ, Oppenheim FG, Mills JC, Ciorba MA, Fleckenstein JM, Bullitt E. A Role for Salivary Peptides in the Innate Defense Against Enterotoxigenic Escherichia coli. J Infect Dis. 2018 04 11; 217(9):1435-1441.View Related Profiles.

Bullitt, Esther
Helmerhorst, Eva
Oppenheim, Frank

PMID: 29528423; PMCID: PMC5894089; DOI: 10.1093/infdis/jiy032;

Wiklund K, Zhang H, Stangner T, Singh B, Bullitt E, Andersson M. A drag force interpolation model for capsule-shaped cells in fluid flows near a surface. Microbiology. 2018 04; 164(4):483-494. PMID: 29509130

Epler Barbercheck CR, Bullitt E, Andersson M. Bacterial Adhesion Pili. Subcell Biochem. 2018; 87:1-18. PMID: 29464555

Rossignol ED, Peters KN, Connor JH, Bullitt E. Zika virus induced cellular remodelling. Cell Microbiol. 2017 Aug; 19(8).View Related Profiles.

Bullitt, Esther
Rossignol, Evan
Connor, John

PMID: 28318141; PMCID: PMC5561415; DOI: 10.1111/cmi.12740;

Singh B, Mortezaei N, Savarino SJ, Uhlin BE, Bullitt E, Andersson M. Antibodies Damage the Resilience of Fimbriae, Causing Them To Be Stiff and Tangled. J Bacteriol. 2017 Jan 01; 199(1). PMID: 27795330; PMCID: PMC5165098; DOI: 10.1128/JB.00665-16;

Rossignol ED, Yang JE, Bullitt E. The Role of Electron Microscopy in Studying the Continuum of Changes in Membranous Structures during Poliovirus Infection. Viruses. 2015 Oct; 7(10):5305-18.View Related Profiles.

Bullitt, Esther
Rossignol, Evan
Yang, Jie

PMID: 26473912; PMCID: PMC4632382; DOI: 10.3390/v7102874;

Singh B, Mortezaei N, Uhlin BE, Savarino SJ, Bullitt E, Andersson M. Antibody-mediated disruption of the mechanics of CS20 fimbriae of enterotoxigenic Escherichia coli. Sci Rep. 2015; 5:13678. PMID: 26411657; PMCID: PMC4585931; DOI: 10.1038/srep13678;

Mortezaei N, Singh B, Zakrisson J, Bullitt E, Andersson M. Biomechanical and structural features of CS2 fimbriae of enterotoxigenic Escherichia coli. Biophys J. 2015 Jul 7; 109(1):49-56. PMID: 26153701; PMCID: PMC4572467; DOI: 10.1016/j.bpj.2015.05.022;

Brown JW, Bullitt E, Sriswasdi S, Harper S, Speicher DW, McKnight CJ. The Physiological Molecular Shape of Spectrin: A Compact Supercoil Resembling a Chinese Finger Trap. PLoS Comput Biol. 2015 Jun; 11(6):e1004302.View Related Profiles.

McKnight, C.
Bullitt, Esther

PMID: 26067675; PMCID: PMC4466138; DOI: 10.1371/journal.pcbi.1004302;

Mortezaei N, Epler CR, Shao PP, Shirdel M, Singh B, McVeigh A, Uhlin BE, Savarino SJ, Andersson M, Bullitt E. Structure and function of enterotoxigenic Escherichia coli fimbriae from differing assembly pathways. Mol Microbiol. 2015 Jan; 95(1):116-26. PMID: 25355550; PMCID: PMC4275653; DOI: 10.1111/mmi.12847;

Mortezaei N, Singh B, Bullitt E, Uhlin BE, Andersson M. P-fimbriae in the presence of anti-PapA antibodies: new insight of antibodies action against pathogens. Sci Rep. 2013; 3:3393. PMID: 24292100; PMCID: PMC3848023; DOI: 10.1038/srep03393;

Wang J, Ptacek JB, Kirkegaard K, Bullitt E. Double-membraned liposomes sculpted by poliovirus 3AB protein. J Biol Chem. 2013 Sep 20; 288(38):27287-98. PMID: 23908350; PMCID: PMC3779724; DOI: 10.1074/jbc.M113.498899;

Wang J, Lyle JM, Bullitt E. Surface for catalysis by poliovirus RNA-dependent RNA polymerase. J Mol Biol. 2013 Jul 24; 425(14):2529-40. PMID: 23583774; PMCID: PMC3711085; DOI: 10.1016/j.jmb.2013.04.007;

Bushkin GG, Motari E, Magnelli P, Gubbels MJ, Dubey JP, Miska KB, Bullitt E, Costello CE, Robbins PW, Samuelson J. ß-1,3-glucan, which can be targeted by drugs, forms a trabecular scaffold in the oocyst walls of Toxoplasma and Eimeria. MBio. 2012; 3(5).View Related Profiles.

Costello, Catherine
Motari, Edwin
Bullitt, Esther
Bushkin, Gary
Samuelson, John
Robbins, Phillips

PMID: 23015739; PMCID: PMC3518913; DOI: 10.1128/mBio.00258-12;

Wang J, Bullitt E, Kirkegaard K. Surface for catalysis by poliovirus RNA dependent RNA polymerase. Microsc Microanal. 2012 Jul; 18 Suppl 2:68-9. PMID: 23177452; DOI: 10.1017/S143192761200219X;

Epler CR, Dickenson NE, Bullitt E, Picking WL. Ultrastructural analysis of IpaD at the tip of the nascent MxiH type III secretion apparatus of Shigella flexneri. J Mol Biol. 2012 Jun 29; 420(1-2):29-39. PMID: 22480614; PMCID: PMC3367090; DOI: 10.1016/j.jmb.2012.03.025;

Andersson M, Björnham O, Svantesson M, Badahdah A, Uhlin BE, Bullitt E. A structural basis for sustained bacterial adhesion: biomechanical properties of CFA/I pili. J Mol Biol. 2012 Feb 3; 415(5):918-28. PMID: 22178477; PMCID: PMC3267891; DOI: 10.1016/j.jmb.2011.12.006;

Tellez AB, Wang J, Tanner EJ, Spagnolo JF, Kirkegaard K, Bullitt E. Interstitial contacts in an RNA-dependent RNA polymerase lattice. J Mol Biol. 2011 Sep 30; 412(4):737-50. PMID: 21839092; PMCID: PMC3249232; DOI: 10.1016/j.jmb.2011.07.053;

Aprikian P, Interlandi G, Kidd BA, Le Trong I, Tchesnokova V, Yakovenko O, Whitfield MJ, Bullitt E, Stenkamp RE, Thomas WE, Sokurenko EV. The bacterial fimbrial tip acts as a mechanical force sensor. PLoS Biol. 2011 May; 9(5):e1000617. PMID: 21572990; PMCID: PMC3091844; DOI: 10.1371/journal.pbio.1000617;

Chatterjee A, Carpentieri A, Ratner DM, Bullitt E, Costello CE, Robbins PW, Samuelson J. Giardia cyst wall protein 1 is a lectin that binds to curled fibrils of the GalNAc homopolymer. PLoS Pathog. 2010; 6(8):e1001059.View Related Profiles.

Chatterjee, Aparajita
Costello, Catherine
Bullitt, Esther
Samuelson, John
Robbins, Phillips

PMID: 20808847; PMCID: PMC2924369; DOI: 10.1371/journal.ppat.1001059;

Spagnolo JF, Rossignol E, Bullitt E, Kirkegaard K. Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays. RNA. 2010 Feb; 16(2):382-93.View Related Profiles.

Bullitt, Esther
Rossignol, Evan

PMID: 20051491; PMCID: PMC2811667; DOI: 10.1261/rna.1955410;

Chatterjee A, Ghosh SK, Jang K, Bullitt E, Moore L, Robbins PW, Samuelson J. Evidence for a "wattle and daub" model of the cyst wall of entamoeba. PLoS Pathog. 2009 Jul; 5(7):e1000498.View Related Profiles.

Bullitt, Esther
Samuelson, John
Robbins, Phillips

PMID: 19578434; PMCID: PMC2698119; DOI: 10.1371/journal.ppat.1000498;

Li YF, Poole S, Nishio K, Jang K, Rasulova F, McVeigh A, Savarino SJ, Xia D, Bullitt E. Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli. Proc Natl Acad Sci U S A. 2009 Jun 30; 106(26):10793-8. PMID: 19515814; PMCID: PMC2705562; DOI: 10.1073/pnas.0812843106;

Kendall A, McDonald M, Bian W, Bowles T, Baumgarten SC, Shi J, Stewart PL, Bullitt E, Gore D, Irving TC, Havens WM, Ghabrial SA, Wall JS, Stubbs G. Structure of flexible filamentous plant viruses. J Virol. 2008 Oct; 82(19):9546-54. PMID: 18667514; PMCID: PMC2546986; DOI: 10.1128/JVI.00895-08;

Turcios-Ruiz RM, Axelrod P, St John K, Bullitt E, Donahue J, Robinson N, Friss HE. Outbreak of necrotizing enterocolitis caused by norovirus in a neonatal intensive care unit. J Pediatr. 2008 Sep; 153(3):339-44. PMID: 18534621; PMCID: PMC7094480; DOI: 10.1016/j.jpeds.2008.04.015;

Mu XQ, Savarino SJ, Bullitt E. The three-dimensional structure of CFA/I adhesion pili: traveler's diarrhea bacteria hang on by a spring. J Mol Biol. 2008 Feb 22; 376(3):614-20. PMID: 18166195; PMCID: PMC2265596; DOI: 10.1016/j.jmb.2007.10.067;

Verger D, Bullitt E, Hultgren SJ, Waksman G. Crystal structure of the P pilus rod subunit PapA. PLoS Pathog. 2007 May 18; 3(5):e73. PMID: 17511517; PMCID: PMC1868955; DOI: 10.1371/journal.ppat.0030073;

Poole ST, McVeigh AL, Anantha RP, Lee LH, Akay YM, Pontzer EA, Scott DA, Bullitt E, Savarino SJ. Donor strand complementation governs intersubunit interaction of fimbriae of the alternate chaperone pathway. Mol Microbiol. 2007 Mar; 63(5):1372-84. PMID: 17302815

Jiang ZG, Gantz D, Bullitt E, McKnight CJ. Defining lipid-interacting domains in the N-terminal region of apolipoprotein B. Biochemistry. 2006 Oct 3; 45(39):11799-808.View Related Profiles.

McKnight, C.
Bullitt, Esther

PMID: 17002280; PMCID: PMC2519233; DOI: 10.1021/bi060600w;

Mu XQ, Bullitt E. Structure and assembly of P-pili: a protruding hinge region used for assembly of a bacterial adhesion filament. Proc Natl Acad Sci U S A. 2006 Jun 27; 103(26):9861-6. PMID: 16782819; PMCID: PMC1502544; DOI: 10.1073/pnas.0509620103;

Mu XQ, Jiang ZG, Bullitt E. Localization of a critical interface for helical rod formation of bacterial adhesion P-pili. J Mol Biol. 2005 Feb 11; 346(1):13-20. PMID: 15663923

Frenkiel-Krispin D, Sack R, Englander J, Shimoni E, Eisenstein M, Bullitt E, Horowitz-Scherer R, Hayes CS, Setlow P, Minsky A, Wolf SG. Structure of the DNA-SspC complex: implications for DNA packaging, protection, and repair in bacterial spores. J Bacteriol. 2004 Jun; 186(11):3525-30. PMID: 15150240; PMCID: PMC415783

Mu XQ, Egelman EH, Bullitt E. Structure and function of Hib pili from Haemophilus influenzae type b. J Bacteriol. 2002 Sep; 184(17):4868-74. PMID: 12169612; PMCID: PMC135281

Lyle JM, Bullitt E, Bienz K, Kirkegaard K. Visualization and functional analysis of RNA-dependent RNA polymerase lattices. Science. 2002 Jun 21; 296(5576):2218-22. PMID: 12077417

Saulino ET, Bullitt E, Hultgren SJ. Snapshots of usher-mediated protein secretion and ordered pilus assembly. Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16):9240-5. PMID: 10908657; PMCID: PMC16852; DOI: 10.1073/pnas.160070497;

Cheng W, Bullitt E, Bhattacharyya L, Brewer CF, Makowski L. Electron microscopy and x-ray diffraction studies of Lotus tetragonolobus A isolectin cross-linked with a divalent Lewisx oligosaccharide, an oncofetal antigen. J Biol Chem. 1998 Dec 25; 273(52):35016-22. PMID: 9857034

Bullitt E, Makowski L. Bacterial adhesion pili are heterologous assemblies of similar subunits. Biophys J. 1998 Jan; 74(1):623-32. PMID: 9449363; PMCID: PMC1299415

Bullitt E, Rout MP, Kilmartin JV, Akey CW. The yeast spindle pole body is assembled around a central crystal of Spc42p. Cell. 1997 Jun 27; 89(7):1077-86.View Related Profiles.

Akey, Christopher
Bullitt, Esther

PMID: 9215630

Bullitt E, Jones CH, Striker R, Soto G, Jacob-Dubuisson F, Pinkner J, Wick MJ, Makowski L, Hultgren SJ. Development of pilus organelle subassemblies in vitro depends on chaperone uncapping of a beta zipper. Proc Natl Acad Sci U S A. 1996 Nov 12; 93(23):12890-5. PMID: 8917515; PMCID: PMC24016

St Geme JW, Pinkner JS, Krasan GP, Heuser J, Bullitt E, Smith AL, Hultgren SJ. Haemophilus influenzae pili are composite structures assembled via the HifB chaperone. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11913-8. PMID: 8876237; PMCID: PMC38158

Bullitt E, Makowski L. Structural polymorphism of bacterial adhesion pili. Nature. 1995 Jan 12; 373(6510):164-7. PMID: 7816100

Specthrie L, Bullitt E, Horiuchi K, Model P, Russel M, Makowski L. Construction of a microphage variant of filamentous bacteriophage. J Mol Biol. 1992 Dec 5; 228(3):720-4. PMID: 1469710

Bullitt ES, DeRosier DJ, Coluccio LM, Tilney LG. Three-dimensional reconstruction of an actin bundle. J Cell Biol. 1988 Aug; 107(2):597-611.View Related Profiles.

Bullitt, Esther
Coluccio, Lynne

PMID: 3417764; PMCID: PMC2115194

Trachtenberg S, Stokes D, Bullitt E, DeRosier D. Actin and flagellar filaments: two helical structures with variable twist. Ann N Y Acad Sci. 1986; 483:88-99. PMID: 3471141

Weisel JW, Stauffacher CV, Bullitt E, Cohen C. A model for fibrinogen: domains and sequence. Science. 1985 Dec 20; 230(4732):1388-91. PMID: 4071058

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 74 publications over 30 distinct years, with a maximum of 10 publications in 2022

Bar chart showing 74 publications over 30 distinct years, with a maximum of 10 publications in 2022

Year	Publications
1985	1
1986	1
1988	1
1992	1
1995	1
1996	2
1997	1
1998	2
2000	1
2002	2
2004	2
2006	2
2007	3
2008	2
2009	2
2010	2
2011	3
2012	3
2013	3
2014	1
2015	4
2016	1
2017	1
2018	3
2019	4
2020	5
2021	4
2022	10
2023	5
2024	1