Elke Muhlberger, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Philipps-Universität Marburg
MA, Philipps-Universität Marburg



Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2018 (PI)
NIH/National Institute of Allergy & Infe
1R21AI126457-01

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2018 (PI of Sub-Project / SP)
PI: Ronald B. Corley, Ph.D.
NIH/National Institute of Allergy & Infe
2UC7AI095321-03

Deep Characterization of Rousettus Aegyptiacus Immune System: Use of bats/nonhuman primates to compare immune responses during asymtomatic/symptomatic filovirus infections
01/15/2014 - 03/14/2018 (PI)
The Geneva Foundation DOD DTRA


Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (SP Co-PI of Sub-Project / SP)
PI: John H. Connor, PhD
Becton, Dickinson and Company Paul G. Allen Fdn


SPR: Novel SPR Barrier Technology (the "USAID Agreement")
11/01/2015 - 10/31/2016 (PI)
SPR Advanced Technologies Inc. USAID


Filovirus replication: initiation mechanism and role of RNA secondary structures
08/05/2014 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infe
5R03AI114293-02

Early Host Immune Response in Protection Against Filovirus Infection
06/15/2009 - 05/31/2015 (PI)
NIH/National Institute of Allergy & Infe
5U01AI082954-05

IMVC Pilot Project: Mechanisms of Ebola Virus-induced Vascular Dysfunction
05/01/2013 - 04/30/2015 (PI)
Augusta University NIH NIAID
5U01AI083005-05

The Antiviral Function of the Interferon-Simulated Gene IFIT1
05/01/2012 - 04/30/2014 (PI)
Washington University NIH NIAID
5U01AI083005-04




Yr Title Project-Sub Proj Pubs
2016 Antiviral responses in iPSC-derived human primary cells to Ebola virus infection 1R21AI126457-01
2016 Integrated Support Services Core 2UC7AI095321-03-8669 1
2015 Filovirus replication: initiation mechanism and role of RNA secondary structures 5R03AI114293-02 3
2014 Filovirus replication: initiation mechanism and role of RNA secondary structures 1R03AI114293-01 3
2013 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-05 9
2013 Biomolecule Production Core 3UC7AI070088-05S3-6796 1
2012 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-04 9
2012 Biomolecule Production Core 3UC7AI070088-05S2-7836 1
2011 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-03 9
2010 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-02 9
Showing 10 of 11 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Brauburger K, Boehmann Y, Krähling V, Mühlberger E. Transcriptional Regulation in Ebola Virus: Effects of Gene Border Structure and Regulatory Elements on Gene Expression and Polymerase Scanning Behavior. J Virol. 2016 Feb; 90(4):1898-909.View Related Profiles. PMID: 26656691; PMCID: PMC4733972; DOI: 10.1128/JVI.02341-15;.
  2. Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses. 2014 Sep; 6(9):3663-82.View Related Profiles. PMID: 25256396; PMCID: PMC4189044; DOI: 10.3390/v6093663;.
  3. Brauburger K, Boehmann Y, Tsuda Y, Hoenen T, Olejnik J, Schümann M, Ebihara H, Mühlberger E. Analysis of the highly diverse gene borders in Ebola virus reveals a distinct mechanism of transcriptional regulation. J Virol. 2014 Nov; 88(21):12558-71.View Related Profiles. PMID: 25142600; PMCID: PMC4248908; DOI: 10.1128/JVI.01863-14;.
  4. Bukreyev AA, Chandran K, Dolnik O, Dye JM, Ebihara H, Leroy EM, Mühlberger E, Netesov SV, Patterson JL, Paweska JT, Saphire EO, Smither SJ, Takada A, Towner JS, Volchkov VE, Warren TK, Kuhn JH. Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013. Arch Virol. 2014 Apr; 159(4):821-30. PMID: 24122154; PMCID: PMC3984924.
  5. Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Arch Virol. 2014 May; 159(5):1229-37.View Related Profiles. PMID: 24190508; PMCID: PMC4010566; DOI: 10.1007/s00705-013-1877-2;.
  6. Gantke T, Boussouf S, Janzen J, Morrice NA, Howell S, Mühlberger E, Ley SC. Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-?B1 p105 complex in co-transfected HEK-293 cells. Biochem J. 2013 Jun 1; 452(2):359-65. PMID: 23557442; PMCID: PMC3727213; DOI: 10.1042/BJ20121873;.
  7. Trunschke M, Conrad D, Enterlein S, Olejnik J, Brauburger K, Mühlberger E. The L-VP35 and L-L interaction domains reside in the amino terminus of the Ebola virus L protein and are potential targets for antivirals. Virology. 2013 Jul 5; 441(2):135-45.View Related Profiles. PMID: 23582637; PMCID: PMC3773471; DOI: 10.1016/j.virol.2013.03.013;.
  8. Olejnik J, Alonso J, Schmidt KM, Yan Z, Wang W, Marzi A, Ebihara H, Yang J, Patterson JL, Ryabchikova E, Mühlberger E. Ebola virus does not block apoptotic signaling pathways. J Virol. 2013 May; 87(10):5384-96.View Related Profiles. PMID: 23468487; PMCID: PMC3648168; DOI: 10.1128/JVI.01461-12;.
  9. Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Lofts LL, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae. Arch Virol. 2013 Jun; 158(6):1425-32.View Related Profiles. PMID: 23358612; PMCID: PMC3669655; DOI: 10.1007/s00705-012-1594-2;.
  10. Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Hensley LE, Honko AN, Jahrling PB, Johnson KM, Kobinger G, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Saphire EO, Smither SJ, Swanepoel R, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Weidmann M, Nichol ST. Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae. Arch Virol. 2013 Jan; 158(1):301-11.View Related Profiles. PMID: 23001720; PMCID: PMC3535543; DOI: 10.1007/s00705-012-1454-0;.
Showing 10 of 53 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 53 publications over 22 distinct years, with a maximum of 5 publications in 2013

YearPublications
19922
19931
19951
19962
19982
19993
20003
20014
20024
20033
20042
20052
20064
20072
20082
20092
20102
20112
20121
20135
20143
20151

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


72 E. Concord St Instructional (L)
Boston MA 02118
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