Ronald Corley | Profiles RNS

Ronald B. Corley, Ph.D.

Director

Boston University

Dept of National Emerging Infectious Disease Lab

PhD, Duke University

Websites

	Microbiology Faculty
	National Emerging Infectious Diseases Laboratories (NEIDL)
	Immunology Training Program Faculty

ORCID : 0000-0002-7498-0545

My research focuses on the relationship between innate and adaptive immunity, and how components of the two discrete systems interact to generate long-lasting protective immune responses. One area of focus has been on the role of IgM antibodies as efficient bridges of innate and adaptive immunity. IgM antibodies serve to concentrate antigens into secondary lymphoid organs, accelerating the production of protective immune responses along with affinity matured antibodies. IgM also contributes to preventing pathogens from initially localizing into vital organs. The innate functions of IgM can be attributed, at least in part, to its ability to concentrate immune complexes in the foci of the spleen, where innate B cells in the marginal zones traffic the complexes to follicular dendritic cells, stromal elements that promote efficient germinal center formation. These functions require native organization around the marginal sinuses for efficient adjuvant effects of IgM.

The laboratory also focuses on the immune consequences of infection with highly pathogenic hemorrhagic fever viruses, including filoviruses. Patients infected with these viruses often fail to make adaptive immune responses and succumb to infection. While this is often attributed to dysfunctional innate immune responses, the nature of the defects in immune responses to these viruses is poorly understood. We are interested in in the very early immune responses to these viruses, in order to map how they affect the ability of infected animals to initiate adaptive immune responses, and identify the components of infection that lead to abnormal cytokine responses that characterize infection with these viruses.

Professor
Boston University School of Medicine
Microbiology

Chair of Microbiology
Boston University School of Medicine
Microbiology

Mentor for Graduate Medical Students
Boston University School of Medicine, Division of Graduate Medical Sciences

BU Sponsored Research
NIH RePORTER Sponsored Research

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2021 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-04

National Emerging Infectious Diseases Laboratories Operations
06/01/2015 - 05/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-02

National Emerging Infectious Diseases Laboratories Operations
06/01/2014 - 05/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-02

IgM Polymerization and J Chain Expression
02/01/2000 - 01/31/2006 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5 R01 AI31209 13

Functional Characterization of Genes Involved in V(D)J Recombination and DNA Repair
07/01/1998 - 06/30/2003 (Dept Sponsor)
Leukemia Society of America

Cellular and Molecular Events in B Lymphocyte Activation
05/01/1997 - 02/28/2003 (PI)
NIH/National Cancer Institute
5 R01 CA36642 19

Yr	Title	Project-Sub Proj	Pubs
2018	National Emerging Infectious Diseases Laboratories Operations	5UC7AI095321-05	1
2018	Administrative Core	5UC7AI095321-05-8664	1
2016	National Emerging Infectious Diseases Laboratories Operations	2UC7AI095321-03	1
2016	Administrative Core	2UC7AI095321-03-8664	1
2014	National Emerging Infectious Diseases Laboratories Operations	1UC7AI095321-01	1
2013	Immunology Core	3UC7AI070088-05S3-6798	1
2012	Immunology Core	3UC7AI070088-05S2-7838	1
2011	Immunology Core	3UC7AI070088-05S1-7212	1
2004	IGM POLYMERIZATION AND J CHAIN EXPRESSION	5R01AI031209-13	19
2003	IGM POLYMERIZATION AND J CHAIN EXPRESSION	5R01AI031209-12	19

Showing 10 of 32 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

Schultz MJ, Isern S, Michael SF, Corley RB, Connor JH, Frydman HM. Variable Inhibition of Zika Virus Replication by Different Wolbachia Strains in Mosquito Cell Cultures. J Virol. 2017 Jul 15; 91(14).View Related Profiles.

Connor, John
Corley, Ronald

PMID: 28446677.

Olejnik J, Ryabchikova E, Corley RB, Mühlberger E. Intracellular events and cell fate in filovirus infection. Viruses. 2011 Aug; 3(8):1501-31.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Corley, Ronald

PMID: 21927676; PMCID: PMC3172725; DOI: 10.3390/v3081501;.

Yasuda K, Richez C, Uccellini MB, Richards RJ, Bonegio RG, Akira S, Monestier M, Corley RB, Viglianti GA, Marshak-Rothstein A, Rifkin IR. Requirement for DNA CpG content in TLR9-dependent dendritic cell activation induced by DNA-containing immune complexes. J Immunol. 2009 Sep 1; 183(5):3109-17.View Related Profiles.

Marshak-Rothstein, Ann
Viglianti, Gregory
Rifkin, Ian
Yasuda, Kei
Bonegio, Ramon
Corley, Ronald

PMID: 19648272; PMCID: PMC2860771; DOI: 10.4049/jimmunol.0900399;.

Busconi L, Bauer JW, Tumang JR, Laws A, Perkins-Mesires K, Tabor AS, Lau C, Corley RB, Rothstein TL, Lund FE, Behrens TW, Marshak-Rothstein A. Functional outcome of B cell activation by chromatin immune complex engagement of the B cell receptor and TLR9. J Immunol. 2007 Dec 1; 179(11):7397-405.View Related Profiles.

Marshak-Rothstein, Ann
Corley, Ronald

PMID: 18025183.

Corley RB, Morehouse EM, Ferguson AR. IgM accelerates affinity maturation. Scand J Immunol. 2005 Jul; 62 Suppl 1:55-61. PMID: 15953185.

Ferguson AR, Corley RB. Accumulation of marginal zone B cells and accelerated loss of follicular dendritic cells in NF-kappaB p50-deficient mice. BMC Immunol. 2005; 6:8. PMID: 15836790; PMCID: PMC1087843.

Doerre S, Mesires KP, Daley KM, McCarty T, Knoetig S, Corley RB. Reductions in I kappa B epsilon and changes in NF-kappa B activity during B lymphocyte differentiation. J Immunol. 2005 Jan 15; 174(2):983-91. PMID: 15634922.

Corley RB. A Guide to Methods in the Biomedical Sciences. Springer Science+Business Media, Inc. New York. 2005.

Youd ME, Luus L, Corley RB. IgM monomers accelerate disease manifestations in autoimmune-prone Fas-deficient mice. J Autoimmun. 2004 Dec; 23(4):333-43. PMID: 15571927.

Ferguson AR, Youd ME, Corley RB. Marginal zone B cells transport and deposit IgM-containing immune complexes onto follicular dendritic cells. Int Immunol. 2004 Oct; 16(10):1411-22. PMID: 15326094.

Showing 10 of 97 results. Show More

Flemming JA, Perkins KH, Luus L, Ferguson AR, Corley RB. Disruption of membrane cholesterol stimulates MyD88-dependent NF-kappaB activation in immature B cells. Cell Immunol. 2004 May; 229(1):68-77. PMID: 15331330.

Corley RB. Chapter 6. Antibodies. In: Immunology, Infection, and Immunity: An Introductory Text. Edited by Pier GB, Lyczak JB, Wetzler LM. ASM Press. Washington, DC. 2004; 113-143.

Li J, Helmerhorst EJ, Corley RB, Luus LE, Troxler RF, Oppenheim FG. Characterization of the immunologic responses to human in vivo acquired enamel pellicle as a novel means to investigate its composition. Oral Microbiol Immunol. 2003 Jun; 18(3):183-91.View Related Profiles.

Helmerhorst, Eva
Oppenheim, Frank
Corley, Ronald

PMID: 12753471.

Youd ME, Ferguson AR, Corley RB. Synergistic roles of IgM and complement in antigen trapping and follicular localization. Eur J Immunol. 2002 Aug; 32(8):2328-37. PMID: 12209646.

Phillips-Quagliata JM, Patel S, Han JK, Arakelov S, Rao TD, Shulman MJ, Fazel S, Corley RB, Everett M, Klein MH, Underdown BJ, Corthésy B. The IgA/IgM receptor expressed on a murine B cell lymphoma is poly-Ig receptor. J Immunol. 2000 Sep 1; 165(5):2544-55. PMID: 10946281.

Reddy PS, Corley RB. The contribution of ER quality control to the biologic functions of secretory IgM. Immunol Today. 1999 Dec; 20(12):582-8. PMID: 10562710.

Doerre S, Corley RB. Constitutive nuclear translocation of NF-kappa B in B cells in the absence of I kappa B degradation. J Immunol. 1999 Jul 1; 163(1):269-77. PMID: 10384125.

Hughey CT, Brewer JW, Colosia AD, Rosse WF, Corley RB. Production of IgM hexamers by normal and autoimmune B cells: implications for the physiologic role of hexameric IgM. J Immunol. 1998 Oct 15; 161(8):4091-7. PMID: 9780180.

Reddy PS, Corley RB. Assembly, sorting, and exit of oligomeric proteins from the endoplasmic reticulum. Bioessays. 1998 Jul; 20(7):546-54. PMID: 9723003.

Corley RB. Antibodies. In: Immunology, Infection, and Immunity: An Introductory Text. Edited by G. Pier and L. Wetzler. ASM Press. Washington, DC. 1998.

Bornemann KD, Brewer JW, Perez E, Doerre S, Sita R, Corley RB. Secretion of soluble pre-B cell receptors by pre-B cells. J Immunol. 1997 Mar 15; 158(6):2551-7. PMID: 9058786.

Brewer JW, Corley RB. Late events in assembly determine the polymeric structure and biological activity of secretory IgM. Mol Immunol. 1997 Mar; 34(4):323-31. PMID: 9244345.

Doerre S, Corley RB. Mouse mammary tumor virus expression in B cells: transcriptional adaptation and the viral life cycle. In: Viral Superantigens, ed. K. Tomonari. CRC Press. Boca Raton, FL. 1997; 71-88.

Brewer JW, Corley RB. Quality control in protein biogenesis: thiol-mediated retention monitors the redox state of proteins in the endoplasmic reticulum. J Cell Sci. 1996 Sep; 109 ( Pt 9):2383-92. PMID: 8886987.

Liou LB, Colosia A, Corley RB, Clarke SH, Scott DW. Differential susceptibility to tolerance induction in vitro of splenic B cells from several transgenic mouse lines. Role of B1 cells. J Immunol. 1995 Jun 15; 154(12):6262-74. PMID: 7759864.

Bornemann KD, Brewer JW, Beck-Engeser GB, Corley RB, Haas IG, Jäck HM. Roles of heavy and light chains in IgM polymerization. Proc Natl Acad Sci U S A. 1995 May 23; 92(11):4912-6. PMID: 7761423; PMCID: PMC41817.

Brewer JW, Randall TD, Parkhouse RM, Corley RB. Mechanism and subcellular localization of secretory IgM polymer assembly. J Biol Chem. 1994 Jun 24; 269(25):17338-48. PMID: 8006043.

Brewer JW, Randall TD, Parkhouse RM, Corley RB. IgM hexamers? Immunol Today. 1994 Apr; 15(4):165-8. PMID: 8198707.

Randall TD, Lund FE, Brewer JW, Aldridge C, Wall R, Corley RB. Interleukin-5 (IL-5) and IL-6 define two molecularly distinct pathways of B-cell differentiation. Mol Cell Biol. 1993 Jul; 13(7):3929-36. PMID: 8321200; PMCID: PMC359931.

Lund FE, Randall TD, Woodland DL, Corley RB. MHC class II limits the functional expression of endogenous superantigens in B cells. J Immunol. 1993 Jan 1; 150(1):78-86. PMID: 8380190.

Corley RB, Lund FE, Randall TD, King LB, Doerre S, Woodland DL. Mouse mammary tumor proviral gene expression in cells of the B lineage. Semin Immunol. 1992 Oct; 4(5):287-96. PMID: 1336679.

Randall TD, Brewer JW, Corley RB. Direct evidence that J chain regulates the polymeric structure of IgM in antibody-secreting B cells. J Biol Chem. 1992 Sep 5; 267(25):18002-7. PMID: 1517233.

Woodland DL, Corley RB. Mouse mammary tumor viruses express genes encoding a number of T cell superantigens. J Immunol. 1992 Jul 15; 149(2):743-4. PMID: 1320644.

Blackman MA, Lund FE, Surman S, Corley RB, Woodland DL. Major histocompatibility complex-restricted recognition of retroviral superantigens by V beta 17+ T cells. J Exp Med. 1992 Jul 1; 176(1):275-80. PMID: 1535369; PMCID: PMC2119304.

Conger JD, Sage HJ, Corley RB. Correlation of antibody multireactivity with variable region primary structure among murine anti-erythrocyte autoantibodies. Eur J Immunol. 1992 Mar; 22(3):783-90. PMID: 1547822.

Randall TD, Parkhouse RM, Corley RB. J chain synthesis and secretion of hexameric IgM is differentially regulated by lipopolysaccharide and interleukin 5. Proc Natl Acad Sci U S A. 1992 Feb 1; 89(3):962-6. PMID: 1736312; PMCID: PMC48365.

Lund FE, Corley RB. Regulated expression of mouse mammary tumor proviral genes in cells of the B lineage. J Exp Med. 1991 Dec 1; 174(6):1439-50. PMID: 1660524; PMCID: PMC2119027.

Woodland DL, Lund FE, Happ MP, Blackman MA, Palmer E, Corley RB. Endogenous superantigen expression is controlled by mouse mammary tumor proviral loci. J Exp Med. 1991 Nov 1; 174(5):1255-8. PMID: 1658187; PMCID: PMC2118998.

Corley RB, Lund FE. Who's zooming who? Curr Biol. 1991 Oct; 1(5):278-80. PMID: 15336096.

Conger JD, Sage HJ, Kawaguchi S, Corley RB. Properties of murine antibodies from different V region families specific for bromelain-treated mouse erythrocytes. J Immunol. 1991 Feb 15; 146(4):1216-9. PMID: 1991963.

Randall TD, King LB, Corley RB. The biological effects of IgM hexamer formation. Eur J Immunol. 1990 Sep; 20(9):1971-9. PMID: 2120070.

King LB, Corley RB. Lipopolysaccharide and dexamethasone induce mouse mammary tumor proviral gene expression and differentiation in B lymphocytes through distinct regulatory pathways. Mol Cell Biol. 1990 Aug; 10(8):4211-20. PMID: 2164635; PMCID: PMC360955.

King LB, Lund FE, White DA, Sharma S, Corley RB. Molecular events in B lymphocyte differentiation. Inducible expression of the endogenous mouse mammary tumor proviral gene, Mtv-9. J Immunol. 1990 Apr 15; 144(8):3218-27. PMID: 2157765.

Conger JD, Sage HJ, Corley RB. Diversity in the available repertoire of murine antibodies reactive with bromelain-treated isologous erythrocytes. J Immunol. 1989 Dec 15; 143(12):4044-52. PMID: 2512347.

King LB, Corley RB. Characterization of a presecretory phase in B-cell differentiation. Proc Natl Acad Sci U S A. 1989 Apr; 86(8):2814-8. PMID: 2495536; PMCID: PMC287009.

Sharma S, King LB, Corley RB. Molecular events during B lymphocyte differentiation. Induction of endogenous mouse mammary tumor proviral envelope transcripts after B cell stimulation. J Immunol. 1988 Oct 1; 141(7):2510-8. PMID: 2844901.

King LB, Sharma S, Corley RB. Complete coding region sequence of E beta k cDNA clones: lack of polymorphism in the NH2-terminus between E beta k and E beta b molecules. J Immunogenet. 1988 Aug; 15(4):209-14. PMID: 3150763.

Sharma S, King LB, Corley RB. Changes in gene expression in differentiating B lymphocytes. In: Proceedings of the 18th International Leucocyte Culture Conference, ed. J. Mani and J. Dornand. Walter de Gruyter & Co. Berlin. 1988; 591-594.

Sharma S, King LB, Corley RB, Maki R. Comparative sequence analysis of cDNA clones encoding I-A molecules of the CH12 B cell lymphoma: nucleotide differences do not account for their "defective" function in B cell stimulation. Immunol Invest. 1987 Aug; 16(5):425-36. PMID: 3500915.

Dexter CM, Corley RB. Expression of the Fc gamma receptor on Ly-1+ B lymphocytes. Eur J Immunol. 1987 Jun; 17(6):867-71. PMID: 2954830.

Ovnic M, Corley RB. Quantitation of cell surface molecules on a differentiating, Ly-1+ B cell lymphoma. J Immunol. 1987 May 1; 138(9):3075-82. PMID: 3494780.

Corley RB, Dexter CM, Ovnic M. Inducible lymphokines of T cell tumors. Crit Rev Immunol. 1986; 6(1):71-103. PMID: 3522104.

Arnold LW, Lutz PM, Pennell CA, Bishop GA, Corley RB, Haughton G, LoCascio NJ. B cell tumors as models of B lymphocyte differentiation. In: B- Lymphocyte Differentiation, ed. J.C. Cambier. CRC Press, Inc. Boca Raton, FL. 1986; 109-133.

Kuhara T, Haughton G, Corley RB. Antigen-nonspecific T cell-derived factors in B cell activation: differences in the requirements for interleukin 2 in responses of unprimed and primed B cells. Eur J Immunol. 1985 Aug; 15(8):787-93. PMID: 3875491.

Corley RB. Somatic diversification of B cells: a role for autoreactive T lymphocytes. Immunol Today. 1985 Jun; 6(6):178-80. PMID: 25289978; DOI: 10.1016/0167-5699(85)90110-0;.

Corley RB, LoCascio NJ, Ovnic M, Haughton G. Two separate functions of class II (Ia) molecules: T-cell stimulation and B-cell excitation. Proc Natl Acad Sci U S A. 1985 Jan; 82(2):516-20. PMID: 3155862; PMCID: PMC397070.

Corley RB, LoCascio NJ, Ovnic M, Arnold LW, Pillai PS, Scott DW, Haughton G. Three classes of signalling molecules on B-cell membranes. J Cell Biochem. 1985; 27(1):1-12. PMID: 3156869.

Corley RB. Somatic diversification of B cells: A role for auto reactive T lymphocytes. Immunol. Today. 1985; 6:178-180.

Schimpl A, Corley RB. Signals in B cell activation. In: Immune Regulation, ed. M. Feldmann and N.A. Mitchison. Humana Press, Inc. 1985; 61-64.

Pillai PS, Scott DW, White DA, Corley RB. Major histocompatibility complex-restricted and unrestricted interactions in the T cell-dependent activation of hapten-binding B cells. Immunobiology. 1984 May; 166(4-5):345-59. PMID: 6237044.

LoCascio NJ, Haughton G, Arnold LW, Corley RB. Role of cell surface immunoglobulin in B-lymphocyte activation. Proc Natl Acad Sci U S A. 1984 Apr; 81(8):2466-9. PMID: 6232610; PMCID: PMC345082.

Reinisch CL, Sing AP, Bacon ER, Corley RB, Gershon RK. Regulation of B cell lymphomagenesis by a malignant Qal+ inducer T cell clone. J Exp Med. 1984 Mar 1; 159(3):906-20. PMID: 6321629; PMCID: PMC2187257.

LoCascio NJ, Arnold LW, Corley RB, Haughton G. Induced differentiation of a B cell lymphoma with known antigen specificity. J Mol Cell Immunol. 1984; 1(3):177-90. PMID: 6242857.

Livnat S, Corley RB. T cell help in cytotoxic T lymphocyte responses. Role of the I region in helper cell induction. Transplantation. 1983 Jan; 35(1):78-83. PMID: 6218666.

Corley RB, Pillai PS, White DA, Scott DW. Different requirements for the stimulation of resting and activated hapten-specific B cells by helper T cells. In: Intercellular Communication in Leukocyte Function, ed. J.W. Parker and R.L. O'Brien. John Wiley and Sons, Ltd. Sussex. 1983; 213-216.

Corley RB, Arnold LW, Lutz PM, Kuhara T, White DA, Staniszewski C, Haughton G. T cell lymphomas with helper T cell function. In: Intercellular Communication in Leukocyte Function, ed. J.W. Parker and R.L. O'Brien. John Wiley and Sons, Ltd. Sussex. 1983; 521-528.

Corley RB. The regulation of T cell growth: requirements for the activation and replication of antigen-specific interleukin 2 producing T cells. Immunobiology. 1982 Oct; 163(1):63-76. PMID: 6184311.

Pillai PS, Scott DW, Piper M, Corley RB. Effect of recent antigen exposure on the functional expression of B cell subpopulations. J Immunol. 1982 Sep; 129(3):1023-8. PMID: 6179988.

Livnat S, Corley RB. Recruitment of functional subpopulations of T lymphocytes. Initiator T lymphocytes recruit helper T cells for cytotoxic response. Eur J Immunol. 1982 Apr; 12(4):313-9. PMID: 6178602.

Scott DW, Pillai PS, Anderson SJ, Corley RB. Regulation of growth and differentiation in B cell clones and hybrids. Adv Exp Med Biol. 1982; 150:183-200. PMID: 6216777.

Cambier JC, Havran WL, Fernández de Albornoz T, Corley RB. Identification of a brain theta-positive, secretory cell from hematopoietic tissues. J Immunol. 1981 Oct; 127(4):1685-91. PMID: 7196931.

Cambier JC, Corley RB. The effect of second signals on the induction of B cell tolerance: failure of helper T cells to block tolerance induction. Eur J Immunol. 1981 Jul; 11(7):550-6. PMID: 6169534.

Corley RB, Switzer KA, Livnat S. Cellular interactions in cytotoxic T lymphocyte responses. In: The Immune System, vol. 2, ed. C. Steinberg and I. Lefkovits, S. Karger AG. Basel. 1981; 168-174.

Aarden L, Corley RB, Söderberg A, Lefkovits I. Limiting dilution analysis of the suppressive effect mediated by alloantigen-primed cells. Immunology. 1980 Oct; 41(2):399-406. PMID: 6449474; PMCID: PMC1458183.

Lefkovits L, Aarden LA, Corley RB. Ratio-dominance model of suppression: an analysis by limiting dilution. Immunology. 1980 Oct; 41(2):407-13. PMID: 6449475; PMCID: PMC1458165.

Kindred B, Corley RB, Schirrmacher V. The relationship between alloantigen responses in nude mice injected with a low number of congenic thymus cells. Thymus. 1980 Sep; 2(2):83-92. PMID: 7003827.

Corley RB, Switzer KA, Hudson DE, Cooley MA. Multiple pathways of T-T interaction in the generation of cytotoxic T lymphocytes to alloantigens. J Exp Med. 1980 May 1; 151(5):1125-38. PMID: 6966319; PMCID: PMC2185861.

Kindred B, Bösing-Schneider R, Corley RB. In vivo activity of a nonspecific T cell-replacing factor. J Immunol. 1979 Jan; 122(1):350-4. PMID: 153929.

Corley RB. Quantitative analysis of secondary MLR: Alloreactive populations are composed of multiple clones. In: HLA Antigens in Clinical Medicine and Biology, ed. S. Ferrone, E.S. Curtoni, and S. Gorini. Garland Publishing, Inc. New York. 1979; 124-133.

Corley RB, Kindred B, Lefkovits I. Positive and negative allogeneic effects mediated by MLR-primed lymphocytes: quantitation by limiting dilution analysis. J Immunol. 1978 Sep; 121(3):1082-9. PMID: 151116.

Kindred B, Corley RB. Specificity of helper T cells for different antigens. Eur J Immunol. 1978 Jan; 8(1):67-71. PMID: 76566.

Kindred B, Corley RB. A T cell-replacing factor specific for histocompatibility antigens in mice. Nature. 1977 Aug 11; 268(5620):531-2. PMID: 142214.

Corley RB. Responses of alloantigen-primed lymphocytes in vitro. Quantitative analysis of the relative frequency of reactive lymphocytes in primed populations which respond to allogeneic stimulating cells. Eur J Immunol. 1977 Feb; 7(2):93-9. PMID: 872866.

Corley RB. Responses of alloantigen-primed lymphocytes in vitro. The specificity of secondary responses assayed by titration of primed lymphocyte populations. Scand J Immunol. 1977; 6(5):547-53. PMID: 882851.

Corley RB. Responses of alloantigen-primed lymphocytes in vitro. The contribution of increased frequencies of responding lymphocytes to differences between reactivity of normal and primed lymphocyte populations. Scand J Immunol. 1977; 6(6-7):625-33. PMID: 905773.

Corley RB, Kindred B. In vivo responses of alloreactive lymphocytes stimulated in vitro. Helper-cell activity of MLR-primed lymphocytes. Scand J Immunol. 1977; 6(9):923-932. PMID: 143715.

Corley RB, Kindred B. In vivo responses of alloreactive lymphocytes stimulated in vitro. Skin graft rejection mediated by MLR-Primed lymphocytes. Scand J Immunol. 1977; 6(10):991-6. PMID: 144314.

Corley RB, Zimmermann R. Analysis of secondary MLR by titration of in vitro primed human lymphocytes. In: Regulatory Mechanisms in Lymphocyte Activation, ed. D.D. Lucas. Academic Press. New York. 1977; 656-658.

Corley RB, Dawson JR, Amos DB. Stimulation of lymphocytes by allogeneic lymphocytes and lymphoblasts in the presence of anti-HLA antisera. Eur J Immunol. 1976 Apr; 6(4):235-40. PMID: 186270.

Corley RB, Dawson JR, Amos DB. Lymphocyte stimulation in vitro: generation of cytotoxic effector lymphocytes using subcellular fractions of a lymphoid cell line. Cell Immunol. 1975 Mar; 16(1):92-105. PMID: 123177.

Corley RB. In vivo studies on cellular responses against allogeneic human lymphocytes and lymphoblasts cells from continuous cell lines. PhD Thesis. Duke University. 1975.

Delmas-Marsalet Y, Woodbury M, Corley R, Amos DB. [Microlymphocytotoxicity test with anti-IgG antiglobulin and cross reactivity of HL-A antigens]. Nouv Rev Fr Hematol. 1974 May-Jun; 14(3):409-16. PMID: 4277879.

Buckley CE, Dorsey FC, Corley RB, Ralph WB, Woodbury MA, Amos DB. HL-A-linked human immune-response genes. Proc Natl Acad Sci U S A. 1973 Jul; 70(7):2157-61. PMID: 4516211; PMCID: PMC433687.

Amos DB, Corley RB, Kostyu DD. The anamnestic response to HL-A and H-2 antigens. Transplant Proc. 1973 Mar; 5(1):75-7. PMID: 4695956.

Amos, DB, Corley RB, Kostyu DD. Production of HL-A antibodies. In: Symp. Series Immunobiol. Standard. 18. Karger. Basel. 1973; 1-10.

Corley RB, Spees EK, Cabrera-M G, Swanson JL, Amos DB. HL-A antigens of the Guatemalan Ixils. In: Histocompatibility Testing 1972, ed. J. Dausset and J. Colombani. Munksgaard. Copenhagen. 1973; 351-357.

Amos, DB, Corley RB, Kostyu DD, Delmas-Marsalet Y, Woodbury M. The serological structure of HL-A as indicated by cross reactivities: The inclusion of HL-A loci into major human histocompatibility complex H-1. In: Histocompatibility Testing, ed. J. Dausset and J. Colombani. Munksgaard. Copenhagen. 1972; 359-366.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 77 publications over 29 distinct years, with a maximum of 6 publications in 1985 and 1992

Bar chart showing 77 publications over 29 distinct years, with a maximum of 6 publications in 1985 and 1992

Year	Publications
1980	4
1981	3
1982	4
1983	3
1984	4
1985	6
1986	2
1987	3
1988	3
1989	2
1990	3
1991	4
1992	6
1993	2
1994	2
1995	2
1996	1
1997	3
1998	3
1999	2
2000	1
2002	1
2003	1
2004	4
2005	4
2007	1
2009	1
2011	1
2017	1

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

emerging infectious diseases
immunology
microbiology
virology

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