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PhD, University of Connecticut
MS, University of Connecticut
BA, University of Connecticut

Websites

Research
Publications

Development of VLS-modified s-Ontak: a second-generation, Treg-depleting immunotherapy
12/15/2016 - 09/14/2017 (Subcontract PI)
The Johns Hopkins University Maryland TechDevCorp

Training Program in Host-Pathogen Interaction
09/30/2000 - 08/31/2014 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5T32AI007642-10

National Emerging Infectious Diseases Laboratories Operations
06/20/2012 - 07/31/2014 (PI)
NIH/National Institute of Allergy & Infectious Diseases
3UC7AI070088-05S3

National Emerging Infectious Diseases Laboratories Operations
07/01/2006 - 07/31/2014 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI070088-05

Boston University Clinical and Translational Science Award (CTSA) Program UL1
05/01/2008 - 04/30/2013 (Key Person)
PI: David M. Center, MD
NIH/National Center for Health Research Resources
3UL1RR025771-04

National Center for Emerging Infectious Diseases and Biodefense
09/30/2003 - 06/30/2012 (Co-PI)
NIH/National Institute of Allergy & Infectious Diseases
1 UC6 AI58618 01

National Emerging Infectious Diseases Laboratories Operations
07/01/2006 - 04/30/2012 (Co-PI)
NIH/National Institute of Allergy & Infectious Diseases
1 UC7 AI70088 01

New England Regional Center of Excellence (NERCE)
09/04/2003 - 02/28/2013 (PI)
Harvard Medical School NIH-NIAID

Peptide Activators of Diphtheria Toxin Repressor (Dtxr)
02/01/2005 - 01/01/2011 (PI)
NIH-NIAID
5 R01 AI021628-24

Immuno - Prophylaxis - Core B: Bacteriology (Tularemia - Murphy)
09/15/2003 - 02/28/2009 (PI)
NIH-NIAID
5 U19 AI056543-05 (A)

Immuno - Prophylaxis - Core C: Administration (Tularemia)
09/15/2003 - 02/28/2009 (PI)
NIH-NIAID
5 U19 AI056543-05 (A)

Immuno - Prophylaxis - Project 2: (Tularemia - Murphy)
09/15/2003 - 02/28/2009 (PI)
NIH-NIAID
5 U19 AI056543-05 (A)

Immuno Prophylaxis - Project 3: Diagnostics (Tularemia - Murphy)
09/15/2003 - 02/28/2009 (PI)
NIH-NIAID
5 U19 AI56543-05 (A)

Diptheria + Anthrax Toxins: Mechanisms of Cell Entry
07/01/2003 - 12/31/2008 (PI)
NIH-NIAID
5R01AI55945-05 (A)

Novel Targeted Reagents that Modify Oncogene Expression
04/01/2005 - 03/31/2008 (PI)
NIH-NCI
5 R21 CA112228-02

Diphtheria Tox Repressor
12/01/1998 - 01/31/2005 (PI)
NIH-NIAID
5 R01 AI21628-19 (E)

Mechanism Of Fusion Toxic Entr
05/01/1998 - 11/01/2002 (PI)
NIH-NCI
5 R01 CA60934-08 (B)

Showing 10 of 13 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2024	Immunotherapy to deplete key Treg subsets in solid tumors	1R44CA295167-01
2015	Biosecurity	5UC7AI095321-02-6078	1
2015	Integrated Support Services-Animal	5UC7AI095321-02-6081	1
2015	Administration	5UC7AI095321-02-6076	1
2015	Facility Maintenance	5UC7AI095321-02-6077	1
2015	Environmental Health & Biosafety Regulations and Requirements	5UC7AI095321-02-6079	1
2015	Regulatory Compliance	5UC7AI095321-02-6080	1
2014	Administration	1UC7AI095321-01-6076	1
2014	Facility Maintenance	1UC7AI095321-01-6077	1
2014	Biosecurity	1UC7AI095321-01-6078	1

Showing 10 of 95 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Gupta S, Cheung L, Pokkali S, Winglee K, Guo H, Murphy JR, Bishai WR. Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. J Infect Dis. 2017 Jun 15; 215(12):1883-1887. PMID: 28863467

Tamayo AG, Slater L, Taylor-Parker J, Bharti A, Harrison R, Hung DT, Murphy JR. GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro. Mol Microbiol. 2011 Sep; 81(5):1390-401.View Related Profiles.

Bharti, Ajit
Murphy, John
Harrison, Robert

PMID: 21797942; PMCID: PMC4041151; DOI: 10.1111/j.1365-2958.2011.07770.x;

Wan ES, Hokanson JE, Murphy JR, Regan EA, Make BJ, Lynch DA, Crapo JD, Silverman EK. Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study. Am J Respir Crit Care Med. 2011 Jul 1; 184(1):57-63.View Related Profiles.

Wan, Emily
Murphy, John

PMID: 21493737; PMCID: PMC3172890; DOI: 10.1164/rccm.201101-0021OC;

Murphy JR. Mechanism of diphtheria toxin catalytic domain delivery to the eukaryotic cell cytosol and the cellular factors that directly participate in the process. Toxins (Basel). 2011 Mar; 3(3):294-308. PMID: 22069710; PMCID: PMC3202816; DOI: 10.3390/toxins3030294;

Lasalle-Williams M, Nuss R, Le T, Cole L, Hassell K, Murphy JR, Ambruso DR. Extended red blood cell antigen matching for transfusions in sickle cell disease: a review of a 14-year experience from a single center (CME). Transfusion. 2011 Aug; 51(8):1732-9. PMID: 21332724; DOI: 10.1111/j.1537-2995.2010.03045.x;

Phasomkusolsil S, Lerdthusnee K, Khuntirat B, Kongtak W, Pantuwatana K, Murphy JR. Effect of temperature on laboratory reared Anopheles dirus Peyton and Harrison and Anopheles sawadwongporni Rattanarithikul and Green. Southeast Asian J Trop Med Public Health. 2011 Jan; 42(1):63-70. PMID: 21323167

Trujillo C, Taylor-Parker J, Harrison R, Murphy JR. Essential lysine residues within transmembrane helix 1 of diphtheria toxin facilitate COPI binding and catalytic domain entry. Mol Microbiol. 2010 May; 76(4):1010-9.View Related Profiles.

Murphy, John
Harrison, Robert

PMID: 20398220; PMCID: PMC4113555; DOI: 10.1111/j.1365-2958.2010.07159.x;

Wright DG, Zhang Y, Murphy JR. Effective delivery of antisense peptide nucleic acid oligomers into cells by anthrax protective antigen. Biochem Biophys Res Commun. 2008 Nov 7; 376(1):200-5. PMID: 18774771; PMCID: PMC2581503; DOI: 10.1016/j.bbrc.2008.08.124;

Chiavolini D, Weir S, Murphy JR, Wetzler LM. Neisseria meningitidis PorB, a Toll-like receptor 2 ligand, improves the capacity of Francisella tularensis lipopolysaccharide to protect mice against experimental tularemia. Clin Vaccine Immunol. 2008 Sep; 15(9):1322-9.View Related Profiles.

Murphy, John
Wetzler, Lee
Weir, Susan

PMID: 18614668; PMCID: PMC2546688; DOI: 10.1128/CVI.00125-08;

Tamayo AG, Bharti A, Trujillo C, Harrison R, Murphy JR. COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro. Proc Natl Acad Sci U S A. 2008 Apr 1; 105(13):5254-9.View Related Profiles.

Bharti, Ajit
Murphy, John
Harrison, Robert

PMID: 18356299; PMCID: PMC2278175; DOI: 10.1073/pnas.0710100105;

Showing 10 of 42 results. Show More

Chiavolini D, Alroy J, King CA, Jorth P, Weir S, Madico G, Murphy JR, Wetzler LM. Identification of immunologic and pathologic parameters of death versus survival in respiratory tularemia. Infect Immun. 2008 Feb; 76(2):486-96.View Related Profiles.

Madico, Guillermo
Murphy, John
Wetzler, Lee
Weir, Susan

PMID: 18025095; PMCID: PMC2223482; DOI: 10.1128/IAI.00862-07;

Trujillo C, Ratts R, Tamayo A, Harrison R, Murphy JR. Trojan horse or proton force: finding the right partner(s) for toxin translocation. Neurotox Res. 2006 Apr; 9(2-3):63-71.View Related Profiles.

Murphy, John
Harrison, Robert

PMID: 16785102

Ratts R, Trujillo C, Bharti A, vanderSpek J, Harrison R, Murphy JR. A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15635-40.View Related Profiles.

Bharti, Ajit
Murphy, John
Harrison, Robert

PMID: 16230620; PMCID: PMC1257389; DOI: 10.1073/pnas.0504937102;

Manabe YC, Hatem CL, Kesavan AK, Durack J, Murphy JR. Both Corynebacterium diphtheriae DtxR(E175K) and Mycobacterium tuberculosis IdeR(D177K) are dominant positive repressors of IdeR-regulated genes in M. tuberculosis. Infect Immun. 2005 Sep; 73(9):5988-94. PMID: 16113319; PMCID: PMC1231048

Rangachari V, Marin V, Bienkiewicz EA, Semavina M, Guerrero L, Love JF, Murphy JR, Logan TM. Sequence of ligand binding and structure change in the diphtheria toxin repressor upon activation by divalent transition metals. Biochemistry. 2005 Apr 19; 44(15):5672-82.View Related Profiles.

Love, John
Murphy, John

PMID: 15823025

Wylie GP, Rangachari V, Bienkiewicz EA, Marin V, Bhattacharya N, Love JF, Murphy JR, Logan TM. Prolylpeptide binding by the prokaryotic SH3-like domain of the diphtheria toxin repressor: a regulatory switch. Biochemistry. 2005 Jan 11; 44(1):40-51.View Related Profiles.

Love, John
Murphy, John

PMID: 15628844

Love JF, vanderSpek JC, Marin V, Guerrero L, Logan TM, Murphy JR. Genetic and biophysical studies of diphtheria toxin repressor (DtxR) and the hyperactive mutant DtxR(E175K) support a multistep model of activation. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2506-11.View Related Profiles.

Love, John
Murphy, John

PMID: 14983039; PMCID: PMC356980

Ando M, Manabe YC, Converse PJ, Miyazaki E, Harrison R, Murphy JR, Bishai WR. Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. Infect Immun. 2003 May; 71(5):2584-90. PMID: 12704132; PMCID: PMC153293

Love JF, VanderSpek JC, Murphy JR. The src homology 3-like domain of the diphtheria toxin repressor (DtxR) modulates repressor activation through interaction with the ancillary metal ion-binding site. J Bacteriol. 2003 Apr; 185(7):2251-8.View Related Profiles.

Love, John
Murphy, John

PMID: 12644496; PMCID: PMC151513

Ratts R, Zeng H, Berg EA, Blue C, McComb ME, Costello CE, vanderSpek JC, Murphy JR. The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex. J Cell Biol. 2003 Mar 31; 160(7):1139-50.View Related Profiles.

Murphy, John
McComb, Mark

PMID: 12668662; PMCID: PMC2172777

Spiering MM, Ringe D, Murphy JR, Marletta MA. Metal stoichiometry and functional studies of the diphtheria toxin repressor. Proc Natl Acad Sci U S A. 2003 Apr 1; 100(7):3808-13. PMID: 12655054; PMCID: PMC153003

Love JF, Murphy JR. Design and development of a novel genetic probe for the analysis of repressor-operator interactions. J Microbiol Methods. 2002 Sep; 51(1):63-72.View Related Profiles.

Love, John
Murphy, John

PMID: 12069891

Sebastian S, Agarwal S, Murphy JR, Genco CA. The gonococcal fur regulon: identification of additional genes involved in major catabolic, recombination, and secretory pathways. J Bacteriol. 2002 Jul; 184(14):3965-74.View Related Profiles.

Genco, Caroline
Murphy, John

PMID: 12081969; PMCID: PMC135177

vanderSpek JC, Sutherland JA, Gill BM, Gorgun G, Foss FM, Murphy JR. Structure function analysis of interleukin 7: requirement for an aromatic ring at position 143 of helix D. Cytokine. 2002 Mar 7; 17(5):227-33. PMID: 12027403

Cosenza L, Rosenbach A, White JV, Murphy JR, Smith T. Comparative model building of interleukin-7 using interleukin-4 as a template: a structural hypothesis that displays atypical surface chemistry in helix D important for receptor activation. Protein Sci. 2000 May; 9(5):916-26. PMID: 10850801; PMCID: PMC2144647

vanderSpek JC, Murphy JR. Fusion protein toxins based on diphtheria toxin: selective targeting of growth factor receptors of eukaryotic cells. Methods Enzymol. 2000; 327:239-49. PMID: 11044987

vanderSpek JC, Murphy JR. Genetic construction, expression, and characterization of diphtheria toxin-based growth factor fusion proteins. Methods Mol Biol. 2000; 145:89-99. PMID: 10820717

Sun L, vanderSpek J, Murphy JR. Isolation and characterization of iron-independent positive dominant mutants of the diphtheria toxin repressor DtxR. Proc Natl Acad Sci U S A. 1998 Dec 8; 95(25):14985-90. PMID: 9844002; PMCID: PMC24562

Cosenza L, Sweeney E, Murphy JR. Disulfide bond assignment in human interleukin-7 by matrix-assisted laser desorption/ionization mass spectroscopy and site-directed cysteine to serine mutational analysis. J Biol Chem. 1997 Dec 26; 272(52):32995-3000. PMID: 9407080

Murphy JR. Protein engineering and design for drug delivery. Curr Opin Struct Biol. 1996 Aug; 6(4):541-5. PMID: 8794167

vanderSpek JC, Sutherland JA, Ratnarathorn M, Howland K, Ciardelli TL, Murphy JR. DAB389 interleukin-2 receptor binding domain mutations. Cytotoxic probes for studies of ligand-receptor interactions. J Biol Chem. 1996 May 24; 271(21):12145-9. PMID: 8647806

vanderSpek JC, Sutherland J, Sampson E, Murphy JR. Genetic construction and characterization of the diphtheria toxin-related interleukin 15 fusion protein DAB389 sIL-15. Protein Eng. 1995 Dec; 8(12):1317-21. PMID: 8869645

Murphy JR, vanderSpek JC. Targeting diphtheria toxin to growth factor receptors. Semin Cancer Biol. 1995 Oct; 6(5):259-67. PMID: 8562903

Tao X, Murphy JR. Determination of the minimal essential nucleotide sequence for diphtheria tox repressor binding by in vitro affinity selection. Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20):9646-50.View Related Profiles.

Murphy, John
Tao, Xiaojing

PMID: 7937822; PMCID: PMC44870

vanderSpek J, Cosenza L, Woodworth T, Nichols JC, Murphy JR. Diphtheria toxin-related cytokine fusion proteins: elongation factor 2 as a target for the treatment of neoplastic disease. Mol Cell Biochem. 1994 Sep; 138(1-2):151-6. PMID: 7898459

vanderSpek J, Cassidy D, Genbauffe F, Huynh PD, Murphy JR. An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells. J Biol Chem. 1994 Aug 26; 269(34):21455-9. PMID: 8063778

vanderSpek JC, Howland K, Friedman T, Murphy JR. Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells. Protein Eng. 1994 Aug; 7(8):985-9. PMID: 7809038

van der Spek J, Hémard A, Dautry-Varsat A, Boquet P, Murphy JR. Epitope tagging of DAB389IL-2: new insights into C-domain delivery to the cytosol of target cells. Leukemia. 1994 Apr; 8 Suppl 1:S144-8. PMID: 7512176

vanderSpek JC, Mindell JA, Finkelstein A, Murphy JR. Structure/function analysis of the transmembrane domain of DAB389-interleukin-2, an interleukin-2 receptor-targeted fusion toxin. The amphipathic helical region of the transmembrane domain is essential for the efficient delivery of the catalytic domain to the cytosol of target cells. J Biol Chem. 1993 Jun 05; 268(16):12077-82. PMID: 8505330

Jean LF, Murphy JR. Diphtheria toxin receptor-binding domain substitution with interleukin 6: genetic construction and interleukin 6 receptor-specific action of a diphtheria toxin-related interleukin 6 fusion protein. Protein Eng. 1991 Dec; 4(8):989-94. PMID: 1817263

Murphy JR, Kelley VE, Strom TB. Interleukin 2 toxin: a step toward selective immunomodulation. Am J Kidney Dis. 1988 Feb; 11(2):159-62. PMID: 3124610

Murphy JR, Bishai W, Williams D, Bacha P, Borowski M, Parker K, Boyd J, Waters C, Strom TB. Genetic assembly and selective toxicity of diphtheria-toxin-related polypeptide hormone fusion proteins. Biochem Soc Symp. 1987; 53:9-23. PMID: 2847744

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Contact for Mentoring:

Yr	Title	Project-Sub Proj	Pubs
2024	Immunotherapy to deplete key Treg subsets in solid tumors	1R44CA295167-01
2015	Biosecurity	5UC7AI095321-02-6078	1
2015	Integrated Support Services-Animal	5UC7AI095321-02-6081	1
2015	Administration	5UC7AI095321-02-6076	1
2015	Facility Maintenance	5UC7AI095321-02-6077	1
2015	Environmental Health & Biosafety Regulations and Requirements	5UC7AI095321-02-6079	1
2015	Regulatory Compliance	5UC7AI095321-02-6080	1
2014	Administration	1UC7AI095321-01-6076	1
2014	Facility Maintenance	1UC7AI095321-01-6077	1
2014	Biosecurity	1UC7AI095321-01-6078	1
2014	Environmental Health &Biosafety Regulations and Requirements	1UC7AI095321-01-6079	1
2014	Integrated Support Services-Animal	1UC7AI095321-01-6081	1
2014	Regulatory Compliance	1UC7AI095321-01-6080	1
2013	Community Relations Core	3UC7AI070088-05S3-6807	1
2013	Administration Core	3UC7AI070088-05S3-6811	1
2012	COPI interactions mediate toxin entry: a common shared mechanism of translocation	5U54AI057159-09-5568	421
2012	Community Relations Core	3UC7AI070088-05S2-9002	1
2012	Administration Core	3UC7AI070088-05S2-9006	1
2012	Training Program in Host Pathogen Interaction	5T32AI007642-10	17
2011	Biomolecule Core	3UC7AI070088-05S1-7210	1
2011	MUSSEL ADHESIVE PROTEINS	5P41RR002301-26-5385	655
2011	COPI interactions mediate toxin entry: a common shared mechanism of translocation	5U54AI057159-08-5568	421
2011	SYNTHESIS OF DOPA-MODIFIED PEG	5P41RR002301-26-5386	655
2011	TRAINING IN THE USE OF BRUKER AND VARIAN SPECTROMETERS AND NMR	5P41RR002301-26-5388	655
2011	SYNTHESIS OF NOVEL MATERIALS BASED ON MUSSEL ADHESIVE PROTEINS	5P41RR002301-26-5387	655
2011	Training Program in Host Pathogen Interaction	5T32AI007642-09	17
2010	Training Program in Host Pathogen Interaction	5T32AI007642-08	17
2010	COPI interactions mediate toxin entry: a common shared mechanism of translocation	5U54AI057159-07-5568	421
2009	COPI interactions mediate toxin entry: a common shared mechanism of translocation	2U54AI057159-06-5568	421
2009	Training Program in Host Pathogen Interaction	5T32AI007642-07	17
2009	Peptide Activators of Diphtheria Toxin Repressor(DtxR)	5R01AI021628-24	50
2008	Training Program in Host Pathogen Interaction	2T32AI007642-06A2	17
2008	Peptide Activators of Diphtheria Toxin Repressor(DtxR)	5R01AI021628-23	50
2007	Immuno-Prophylaxis-Therapy &Diagnosis of Tularemia	5U19AI056543-05	5
2007	Diphtheria &Anthrax Toxins: Mechanisms of Cell Entry	5R01AI055945-05
2007	Peptide Activators of Diphtheria Toxin Repressor(DtxR)	5R01AI021628-22	50
2006	ID OF CYTOSOLIC TRANSLOCATION FACTORS INVOLVED IN BACTERIAL INTOXIFICATION	5P41RR010888-10-7097	259
2006	Novel Targeted Reagents that Modify Oncogene Expression	5R21CA112228-02	1
2006	Immuno-Prophylaxis-Therapy &Diagnosis of Tularemia	5U19AI056543-04	5
2006	Diphtheria &Anthrax Toxins: Mechanisms of Cell Entry	5R01AI055945-04
2006	Peptide Activators of Diphtheria Toxin Repressor(DtxR)	5R01AI021628-21	50
2005	ID OF CYTOSOLIC TRANSLOCATION FACTORS INVOLVED IN BACTERIAL INTOXIFICATION	5P41RR010888-09-134	259
2005	Novel Targeted Reagents that Modify Oncogene Expression	1R21CA112228-01	1
2005	Immuno-Prophylaxis-Therapy &Diagnosis of Tularemia	5U19AI056543-03	5
2005	Diphtheria &Anthrax Toxins: Mechanisms of Cell Entry	5R01AI055945-03
2005	Peptide Activators of Diphtheria Toxin Repressor(DtxR)	2R01AI021628-20	50
2004	ID OF CYTOSOLIC TRANSLOCATION FACTORS INVOLVED IN BACTERIAL INTOXIFICATION	5P41RR010888-08-134	259
2004	Diphtheria &Anthrax Toxins: Mechanisms of Cell Entry	5R01AI055945-02
2004	TRAINGING PROGRAM IN HOST-PATHOGEN INTERACTION	5T32AI007642-05	17
2004	DIPHTHERIA TOX REPRESSOR: GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-19	50
2003	Diphtheria &Anthrax Toxins: Mechanisms of Cell Entry	1R01AI055945-01
2003	TRAINGING PROGRAM IN HOST-PATHOGEN INTERACTION	5T32AI007642-04	17
2003	DIPHTHERIA TOX REPRESSOR: GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-18	50
2002	TRAINGING PROGRAM IN HOST-PATHOGEN INTERACTION	5T32AI007642-03	17
2002	DIPHTHERIA TOX REPRESSOR: GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-17	50
2001	TRAINGING PROGRAM IN HOST-PATHOGEN INTERACTION	5T32AI007642-02	17
2001	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	5R01CA060934-08	9
2001	DIPHTHERIA TOX REPRESSOR: GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-16	50
2000	TRAINGING PROGRAM IN HOST-PATHOGEN INTERACTION	1T32AI007642-01	17
2000	MOLECULAR BIOLOGY PROGRAM	5R01CA048626-11-1	29
2000	IL7 AND IL7R TARGETED THERAPEUTIC AGENTS FOR LEUKEMIA	5R01CA048626-11	29
2000	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	5R01CA060934-07	9
2000	DIPHTHERIA TOX REPRESSOR: GENETIC &STRUCTURAL ANALYSIS	2R01AI021628-15	50
1999	MOLECULAR BIOLOGY PROGRAM	5R01CA048626-10-1	29
1999	IL7 AND IL7R TARGETED THERAPEUTIC AGENTS FOR LEUKEMIA	5R01CA048626-10	29
1999	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	5R01CA060934-06	9
1999	DIPHTHERIA TOX REPRESSOR--GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-14	50
1998	MOLECULAR BIOLOGY PROGRAM	2R01CA048626-09-1	29
1998	IL7 AND IL7R TARGETED THERAPEUTIC AGENTS FOR LEUKEMIA	2R01CA048626-09	29
1998	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	5R01CA060934-05	9
1998	DIPHTHERIA TOX REPRESSOR--GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-13	50
1997	MOLECULAR BIOLOGY PROGRAM	7U19CA048626-08-1	27
1997	IL7 AND IL7R TARGETED THERAPEUTIC AGENTS FOR LEUKEMIA	5U19CA048626-08	27
1997	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	2R01CA060934-04A1	9
1997	DIPHTHERIA TOX REPRESSOR--GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-12	50
1996	IL7 AND IL7R TARGETED THERAPEUTIC AGENTS FOR LEUKEMIA	7U19CA048626-07	27
1996	DIPHTHERIA TOX REPRESSOR--GENETIC &STRUCTURAL ANALYSIS	5R01AI021628-11	50
1996	MOLECULAR BIOLOGY PROGRAM	7U19CA048626-07-1	27
1995	IL7 AND IL7R TARGETED THERAPEUTIC AGENTS FOR LEUKEMIA	2U19CA048626-06	27
1995	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	5R01CA060934-03	9
1995	DIPHTHERIA TOX REPRESSOR--GENETIC &STRUCTURAL ANALYSIS	2R01AI021628-10A1	50
1994	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	5R01CA060934-02	9
1994	CELL-RECEPTOR SPECIFIC RIBOSOME INACTIVATORS	5R01CA056889-03	1
1993	MECHANISM OF FUSION TOXIN ENTRY INTO TARGET CELLS	1R01CA060934-01	9
1993	CELL-RECEPTOR SPECIFIC RIBOSOME INACTIVATORS	5R01CA056889-02	1
1993	MOLECULAR MECHANISM(S) OF DIPHTHERIA TOX REGULATION	5R01AI021628-09	50
1992	CELL-RECEPTOR SPECIFIC RIBOSOME INACTIVATORS	1R01CA056889-01	1
1992	GROWTH FACTOR RECEPTOR TARGETED TOXINS FOR LEUKEMIA	5U01CA048626-05	37
1992	MOLECULAR MECHANISM(S) OF DIPHTHERIA TOX REGULATION	5R01AI021628-08	50
1989	GROWTH FACTOR RECEPTOR TARGETED TOXINS FOR LEUKEMIA	5U01CA048626-02	37
1989	DIPHTHERIA TOXIN-RELATED PEPTIDE HORMONE GENE FUSIONS	2R01CA041746-04	24
1989	VIRULENCE FACTORS OF CORYNEBACTERIUM DIPHTHERIAE	5R01AI021628-06	50
1986	DIPHTHERIA TOXIN-RELATED PEPTIDE HORMONE GENE FUSIONS	1R01CA041746-01	24
1986	MOLECULAR GENETICS OF VIBRO CHOLERAE HEMOLYSIN	5R22AI022661-02	1
1986	VIRULENCE FACTORS OF CORYNEBACTERIUM DIPHTHERIAE	5R01AI021628-03	50