Elke Muhlberger, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Philipps-Universität Marburg
MA, Philipps-Universität Marburg



Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences




Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2018 (PI)
NIH/National Institute of Allergy & Infe
1R21AI126457-01

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2018 (PI of Sub-Project / SP)
PI: Ronald B. Corley, Ph.D.
NIH/National Institute of Allergy & Infe
2UC7AI095321-03

Deep Characterization of Rousettus Aegyptiacus Immune System: Use of bats/nonhuman primates to compare immune responses during asymtomatic/symptomatic filovirus infections
01/15/2014 - 03/14/2018 (PI)
The Geneva Foundation DOD DTRA


Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (SP Co-PI of Sub-Project / SP)
PI: John H. Connor, PhD
Becton, Dickinson and Company Paul G. Allen Fdn


SPR: Novel SPR Barrier Technology (the "USAID Agreement")
11/01/2015 - 10/31/2016 (PI)
SPR Advanced Technologies Inc. USAID


Filovirus replication: initiation mechanism and role of RNA secondary structures
08/05/2014 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infe
5R03AI114293-02

Early Host Immune Response in Protection Against Filovirus Infection
06/15/2009 - 05/31/2015 (PI)
NIH/National Institute of Allergy & Infe
5U01AI082954-05

IMVC Pilot Project: Mechanisms of Ebola Virus-induced Vascular Dysfunction
05/01/2013 - 04/30/2015 (PI)
Augusta University NIH NIAID
5U01AI083005-05

The Antiviral Function of the Interferon-Simulated Gene IFIT1
05/01/2012 - 04/30/2014 (PI)
Washington University NIH NIAID
5U01AI083005-04




Yr Title Project-Sub Proj Pubs
2016 Antiviral responses in iPSC-derived human primary cells to Ebola virus infection 1R21AI126457-01
2016 Integrated Support Services Core 2UC7AI095321-03-8669 1
2015 Filovirus replication: initiation mechanism and role of RNA secondary structures 5R03AI114293-02 3
2014 Filovirus replication: initiation mechanism and role of RNA secondary structures 1R03AI114293-01 3
2013 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-05 9
2013 Biomolecule Production Core 3UC7AI070088-05S3-6796 1
2012 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-04 9
2012 Biomolecule Production Core 3UC7AI070088-05S2-7836 1
2011 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-03 9
2010 Early Host Immune Response in Protection Against Filovirus Infection 5U01AI082954-02 9
Showing 10 of 11 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. McElroy AK, Mühlberger E, Muñoz-Fontela C. Immune barriers of Ebola virus infection. Curr Opin Virol. 2018 Feb 13; 28:152-160. PMID: 29452995.
     
  2. Nelson EV, Pacheco JR, Hume AJ, Cressey TN, Deflubé LR, Ruedas JB, Connor JH, Ebihara H, Mühlberger E. An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening. Antiviral Res. 2017 Oct; 146:21-27.View Related Profiles. PMID: 28807685.
     
  3. Olejnik J, Forero A, Deflubé LR, Hume AJ, Manhart WA, Nishida A, Marzi A, Katze MG, Ebihara H, Rasmussen AL, Mühlberger E. Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. J Virol. 2017 Jun 01; 91(11).View Related Profiles. PMID: 28331091; DOI: 10.1128/JVI.00179-17;.
     
  4. Bào Y, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Dolnik O, Dye JM, Ebihara H, Formenty P, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, Patterson JL, Paweska JT, Smither SJ, Takada A, Towner JS, Volchkov VE, Wahl-Jensen V, Kuhn JH. Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses. Viruses. 2017 May 11; 9(5). PMID: 28492506.
     
  5. Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RAM, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiang D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH. Taxonomy of the order Mononegavirales: update 2017. Arch Virol. 2017 Aug; 162(8):2493-2504. PMID: 28389807; DOI: 10.1007/s00705-017-3311-7;.
     
  6. Cressey T, Brauburger K, Mühlberger E. Modeling Ebola Virus Genome Replication and Transcription with Minigenome Systems. Methods Mol Biol. 2017; 1628:79-92.View Related Profiles. PMID: 28573612.
     
  7. Brauburger K, Cressey T, Mühlberger E. Nonradioactive Northern Blot Analysis to Detect Ebola Virus Minigenomic mRNA. Methods Mol Biol. 2017; 1628:143-159.View Related Profiles. PMID: 28573617.
     
  8. Olejnik J, Hume AJ, Leung DW, Amarasinghe GK, Basler CF, Mühlberger E. Filovirus Strategies to Escape Antiviral Responses. Curr Top Microbiol Immunol. 2017; 411:293-322.View Related Profiles. PMID: 28685291.
     
  9. Nelson EV, Schmidt KM, Deflubé LR, Doganay S, Banadyga L, Olejnik J, Hume AJ, Ryabchikova E, Ebihara H, Kedersha N, Ha T, Mühlberger E. Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol. 2016 Aug 15; 90(16):7268-84.View Related Profiles. PMID: 27252530; PMCID: PMC4984654; DOI: 10.1128/JVI.00459-16;.
     
  10. Hume AJ, Ames J, Rennick LJ, Duprex WP, Marzi A, Tonkiss J, Mühlberger E. Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors. Viruses. 2016 Jul 22; 8(7).View Related Profiles. PMID: 27455307; PMCID: PMC4974539; DOI: 10.3390/v8070204;.
     
Showing 10 of 70 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 70 publications over 25 distinct years, with a maximum of 7 publications in 2017

YearPublications
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20177
20181

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


72 E. Concord St Instructional (L)
Boston MA 02118
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