Elke Muhlberger, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Philipps-Universität Marburg
MA, Philipps-Universität Marburg




Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Faculty
Boston University
National Emerging Infectious Disease Lab


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences


Member
Boston University
Genome Science Institute




Mechanisms of Marburg virus gene expression
05/08/2018 - 04/30/2023 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R01AI133486-02

Deep characterization of the role biogenesis and function of Ebola virus microRNAs
07/01/2019 - 06/30/2021 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
1R21AI147285-01

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2021 (PI of Sub-Project / SP)
PI: Ronald B. Corley, Ph.D.
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-06

The role of TLR4 signaling in the pathogenesis of filovirus infection
05/10/2018 - 04/30/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI135912-02

Deciphering the pathogenic potential of Lloviu virus, a novel filovirus
02/13/2018 - 01/31/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI137793-02

Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2019 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R21AI126457-02

Deep Characterization of Rousettus Aegyptiacus Immune System: Use of bats/nonhuman primates to compare immune responses during asymtomatic/symptomatic filovirus infections
01/15/2014 - 06/13/2018 (Subcontract PI)
The Geneva Foundation DOD DTRA


Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (SP Co-PI of Sub-Project / SP)
Becton, Dickinson and Company Paul G. Allen Fdn


SPR: Novel SPR Barrier Technology (the "USAID Agreement")
11/01/2015 - 10/31/2016 (Subcontract PI)
SPR Advanced Technologies Inc. USAID


Filovirus replication: initiation mechanism and role of RNA secondary structures
08/05/2014 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R03AI114293-02

Showing 10 of 13 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2020 Mechanisms of Marburg virus gene expression 5R01AI133486-03 3
2019 Deep characterization of the biogenesis and function of Ebola virus microRNAs 1R21AI147285-01
2019 The role of TLR4 signaling in the pathogenesis of filovirus infection 5R21AI135912-02 2
2019 Mechanisms of Marburg virus gene expression 5R01AI133486-02 3
2019 Deciphering the pathogenic potential of Lloviu virus, a novel filovirus 5R21AI137793-02 2
2019 Integrated Support Services Core 5UC7AI095321-06-8669 1
2018 The role of TLR4 signaling in the pathogenesis of filovirus infection 1R21AI135912-01A1 2
2018 Mechanisms of Marburg virus gene expression 1R01AI133486-01A1 3
2018 Deciphering the pathogenic potential of Lloviu virus, a novel filovirus 1R21AI137793-01 2
2018 Integrated Support Services Core 5UC7AI095321-05-8669 1
Showing 10 of 23 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30.View Related Profiles. PMID: 32637964
     
  2. Amraie R, Napoleon MA, Yin W, Berrigan J, Suder E, Zhao G, Olejnik J, Gummuluru S, Muhlberger E, Chitalia V, Rahimi N. CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells. bioRxiv. 2020 Jun 23.View Related Profiles. PMID: 32607506; DOI: 10.1101/2020.06.22.165803;
     
  3. Pavlovich SS, Darling T, Hume AJ, Davey RA, Feng F, Mühlberger E, Kepler TB. Egyptian Rousette IFN-? Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells. Front Immunol. 2020; 11:435.View Related Profiles. PMID: 32231668
     
  4. Amarasinghe GK, Ayllón MA, Bào Y, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chabi-Jesus C, Chandran K, Chiapponi C, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Griffiths A, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lavazza A, Lee B, Lelli D, Leroy EM, Li J, Maes P, Marzano SL, Moreno A, Mühlberger E, Netesov SV, Nowotny N, Nylund A, Økland AL, Palacios G, Pályi B, Paweska JT, Payne SL, Prosperi A, Ramos-González PL, Rima BK, Rota P, Rubbenstroth D, Shi M, Simmonds P, Smither SJ, Sozzi E, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang LF, Whitfield AE, Williams JV, Zerbini FM, Zhang T, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2019. Arch Virol. 2019 Jul; 164(7):1967-1980.View Related Profiles. PMID: 31089958
     
  5. Hume AJ, Mühlberger E. Distinct Genome Replication and Transcription Strategies within the Growing Filovirus Family. J Mol Biol. 2019 10 04; 431(21):4290-4320.View Related Profiles. PMID: 31260690
     
  6. Olejnik J, Mühlberger E, Hume AJ. Recent advances in marburgvirus research. F1000Res. 2019; 8.View Related Profiles. PMID: 31131088
     
  7. Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, Palacios G, Pályi B, Paweska JT, Smither SJ, Takada A, Towner JS, Wahl V, ICTV Report Consortium. ICTV Virus Taxonomy Profile: Filoviridae. J Gen Virol. 2019 06; 100(6):911-912.View Related Profiles. PMID: 31021739
     
  8. Deflubé LR, Cressey TN, Hume AJ, Olejnik J, Haddock E, Feldmann F, Ebihara H, Fearns R, Mühlberger E. Ebolavirus polymerase uses an unconventional genome replication mechanism. Proc Natl Acad Sci U S A. 2019 04 23; 116(17):8535-8543.View Related Profiles. PMID: 30962389
     
  9. Maes P, Amarasinghe GK, Ayllón MA, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chandran K, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Domier LL, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Ghedin E, Griffiths A, Hewson R, Horie M, Hurwitz JL, Hyndman TH, Jiang D, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lee B, Leroy EM, Li J, Marzano SL, Mühlberger E, Netesov SV, Nowotny N, Palacios G, Pályi B, Paweska JT, Payne SL, Rima BK, Rota P, Rubbenstroth D, Simmonds P, Smither SJ, Song Q, Song T, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang D, Wang LF, Whitfield AE, Williams JV, Yè G, Zerbini FM, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: second update 2018. Arch Virol. 2019 Apr; 164(4):1233-1244.View Related Profiles. PMID: 30663023
     
  10. Olejnik J, Hume AJ, Mühlberger E. Toll-like receptor 4 in acute viral infection: Too much of a good thing. PLoS Pathog. 2018 12; 14(12):e1007390.View Related Profiles. PMID: 30571771
     
Showing 10 of 86 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 86 publications over 27 distinct years, with a maximum of 7 publications in 2017 and 2018

YearPublications
19922
19931
19951
19962
19982
19993
20003
20014
20024
20033
20042
20052
20065
20072
20082
20094
20102
20112
20122
20135
20143
20152
20165
20177
20187
20196
20203

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

72 E. Concord St Instructional (L)
Boston MA 02118
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