Elke Muhlberger, PhD
Associate Professor
Boston University School of Medicine
Dept of Microbiology

PhD, Philipps-Universität Marburg
MA, Philipps-Universität Marburg




Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




Mechanisms of Marburg virus gene expression
05/08/2018 - 04/30/2023 (Co-PI)
PI: Rachel Fearns, PhD
NIH/National Institute of Allergy & Infectious Diseases
1R01AI133486-01A1

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2021 (PI of Sub-Project / SP)
PI: Ronald B. Corley, Ph.D.
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-05

The role of TLR4 signaling in the pathogenesis of filovirus infection
05/10/2018 - 04/30/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
1R21AI135912-01A1

Deciphering the pathogenic potential of Lloviu virus, a novel filovirus
02/13/2018 - 01/31/2020 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI137793-02

Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2019 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI126457-02

Deep Characterization of Rousettus Aegyptiacus Immune System: Use of bats/nonhuman primates to compare immune responses during asymtomatic/symptomatic filovirus infections
01/15/2014 - 06/13/2018 (PI)
The Geneva Foundation DOD DTRA


Point-of-Care Nanotechnology Diagnostic for Differential Fever Diagnosis
10/01/2015 - 10/31/2017 (SP Co-PI of Sub-Project / SP)
PI: John H. Connor, PhD
Becton, Dickinson and Company Paul G. Allen Fdn


SPR: Novel SPR Barrier Technology (the "USAID Agreement")
11/01/2015 - 10/31/2016 (PI)
SPR Advanced Technologies Inc. USAID


Filovirus replication: initiation mechanism and role of RNA secondary structures
08/05/2014 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R03AI114293-02

Early Host Immune Response in Protection Against Filovirus Infection
06/15/2009 - 05/31/2015 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5U01AI082954-05

Showing 10 of 12 results. Show All Results



Yr Title Project-Sub Proj Pubs
2019 Mechanisms of Marburg virus gene expression 5R01AI133486-02
2019 Deciphering the pathogenic potential of Lloviu virus, a novel filovirus 5R21AI137793-02 1
2018 The role of TLR4 signaling in the pathogenesis of filovirus infection 1R21AI135912-01A1 1
2018 Mechanisms of Marburg virus gene expression 1R01AI133486-01A1
2018 Deciphering the pathogenic potential of Lloviu virus, a novel filovirus 1R21AI137793-01 1
2018 Integrated Support Services Core 5UC7AI095321-05-8669 1
2017 Antiviral responses in iPSC-derived human primary cells to Ebola virus infection 5R21AI126457-02 3
2017 Integrated Support Services Core 5UC7AI095321-04-8669 1
2016 Antiviral responses in iPSC-derived human primary cells to Ebola virus infection 1R21AI126457-01 3
2016 Integrated Support Services Core 2UC7AI095321-03-8669 1
Showing 10 of 19 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Amarasinghe GK, Ayllón MA, Bào Y, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chabi-Jesus C, Chandran K, Chiapponi C, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Griffiths A, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lavazza A, Lee B, Lelli D, Leroy EM, Li J, Maes P, Marzano SL, Moreno A, Mühlberger E, Netesov SV, Nowotny N, Nylund A, Økland AL, Palacios G, Pályi B, Paweska JT, Payne SL, Prosperi A, Ramos-González PL, Rima BK, Rota P, Rubbenstroth D, Shi M, Simmonds P, Smither SJ, Sozzi E, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang LF, Whitfield AE, Williams JV, Zerbini FM, Zhang T, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2019. Arch Virol. 2019 Jul; 164(7):1967-1980.View Related Profiles. PMID: 31089958.
     
  2. Olejnik J, Mühlberger E, Hume AJ. Recent advances in marburgvirus research. F1000Res. 2019; 8.View Related Profiles. PMID: 31131088.
     
  3. Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov ??????? ?????? ?????????? SV, Palacios G, Pályi B, Paweska JT, Smither SJ, Takada ???? A, Towner JS, Wahl V, Ictv Report Consortium. ICTV Virus Taxonomy Profile: Filoviridae. J Gen Virol. 2019 Jun; 100(6):911-912.View Related Profiles. PMID: 31021739.
     
  4. Deflubé LR, Cressey TN, Hume AJ, Olejnik J, Haddock E, Feldmann F, Ebihara H, Fearns R, Mühlberger E. Ebolavirus polymerase uses an unconventional genome replication mechanism. Proc Natl Acad Sci U S A. 2019 Apr 23; 116(17):8535-8543.View Related Profiles. PMID: 30962389.
     
  5. Maes P, Amarasinghe GK, Ayllón MA, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chandran K, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Domier LL, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Ghedin E, Griffiths A, Hewson R, Horie M, Hurwitz JL, Hyndman TH, Jiang D, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lee B, Leroy EM, Li J, Marzano SL, Mühlberger E, Netesov SV, Nowotny N, Palacios G, Pályi B, Paweska JT, Payne SL, Rima BK, Rota P, Rubbenstroth D, Simmonds P, Smither SJ, Song Q, Song T, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang D, Wang LF, Whitfield AE, Williams JV, Yè G, Zerbini FM, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: second update 2018. Arch Virol. 2019 Apr; 164(4):1233-1244.View Related Profiles. PMID: 30663023.
     
  6. Olejnik J, Hume AJ, Mühlberger E. Toll-like receptor 4 in acute viral infection: Too much of a good thing. PLoS Pathog. 2018 12; 14(12):e1007390.View Related Profiles. PMID: 30571771.
     
  7. Hume A, Mühlberger E. Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner. J Infect Dis. 2018 Nov 22; 218(suppl_5):S403-S408.View Related Profiles. PMID: 30165526.
     
  8. Olsen ME, Cressey TN, Mühlberger E, Connor JH. Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression. J Virol. 2018 10 15; 92(20).View Related Profiles. PMID: 30045993.
     
  9. Manhart WA, Pacheco JR, Hume AJ, Cressey TN, Deflubé LR, Mühlberger E. A Chimeric Lloviu Virus Minigenome System Reveals that the Bat-Derived Filovirus Replicates More Similarly to Ebolaviruses than Marburgviruses. Cell Rep. 2018 Sep 04; 24(10):2573-2580.e4.View Related Profiles. PMID: 30184492.
     
  10. Pavlovich SS, Lovett SP, Koroleva G, Guito JC, Arnold CE, Nagle ER, Kulcsar K, Lee A, Thibaud-Nissen F, Hume AJ, Mühlberger E, Uebelhoer LS, Towner JS, Rabadan R, Sanchez-Lockhart M, Kepler TB, Palacios G. The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity. Cell. 2018 05 17; 173(5):1098-1110.e18.View Related Profiles. PMID: 29706541.
     
Showing 10 of 81 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 81 publications over 26 distinct years, with a maximum of 7 publications in 2017 and 2018

YearPublications
19922
19931
19951
19962
19982
19993
20003
20014
20024
20033
20042
20052
20064
20072
20082
20094
20102
20112
20122
20135
20143
20152
20165
20177
20187
20195

Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Co-Mentor or Peer Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:

72 E. Concord St Instructional (L)
Boston MA 02118
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