Elke Muhlberger | Profiles RNS

Elke Muhlberger, PhD

Professor

Boston University School of Medicine

Dept of Microbiology

PhD, Philipps-Universität Marburg
MA, Philipps-Universität Marburg

Websites

	Microbiology Faculty
	Immunology Training Program Faculty
	National Emerging Infectious Diseases Laboratories Faculty
	Public Relations - BU Experts

ORCID : 0000-0003-3547-9376

Virologist;
Expert in molecular biology of Marburg and Ebola viruses and other highly pathogenic viruses;
Experienced in BSL4 work;
Focus on virus-host interaction.

Faculty
Boston University
National Emerging Infectious Disease Lab

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

Member
Boston University
Genome Science Institute

BU Research
NIH RePORTER Research

Mechanisms of Marburg virus gene expression
05/08/2018 - 04/30/2023 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R01AI133486-04

Deep characterization of the role biogenesis and function of Ebola virus microRNAs
07/01/2019 - 06/30/2022 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R21AI147285-02

The role of TLR4 signaling in the pathogenesis of filovirus infection
05/10/2018 - 04/30/2022 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI135912-02

COVID Fast Grants
05/01/2020 - 02/28/2022 (PI)
Emergent Ventures at the Mercatus Center, George Mason University

Deciphering the pathogenic potential of Lloviu virus, a novel filovirus
02/13/2018 - 01/31/2022 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI137793-02

Analysis of antibody-dependent enhanced infection by SARS-CoV-2
10/22/2020 - 06/30/2021 (Subcontract PI)
Regeneron Pharmaceuticals, Inc. HHS ASPR BARDA

Applied Research on Disinfection of Surfaces and Hands to Prevent Novel Coronavirus Transmission
07/01/2020 - 06/30/2021 (Subcontract PI)
Trustees of Tufts College, Inc USAID
720FDA20GR00137

National Emerging Infectious Diseases Laboratories Operations
06/01/2016 - 05/31/2021 (PI of Sub-Project / SP)
PI: Ronald B. Corley, Ph.D.
NIH/National Institute of Allergy & Infectious Diseases
5UC7AI095321-07

SARS-CoV-2 infection platforms and development of virological tools to combat the COVID-19 pandemic
05/01/2020 - 04/30/2021 (Subcontract PI)
President & Fellows of Harvard College on behalf of Harvard Medical School China Evergrande Gr

Antiviral responses in iPSC-derived human primary cells to Ebola virus infection
06/30/2016 - 05/31/2019 (Multi-PI)
PI: Elke Muhlberger, PhD
NIH/National Institute of Allergy & Infectious Diseases
5R21AI126457-02

Showing 10 of 17 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2021	Mechanisms of Marburg virus gene expression	5R01AI133486-04	3
2020	Deep characterization of the biogenesis and function of Ebola virus microRNAs	5R21AI147285-02
2020	Mechanisms of Marburg virus gene expression	5R01AI133486-03	3
2020	Integrated Support Services Core	5UC7AI095321-07-8669	1
2019	Deep characterization of the biogenesis and function of Ebola virus microRNAs	1R21AI147285-01
2019	The role of TLR4 signaling in the pathogenesis of filovirus infection	5R21AI135912-02	2
2019	Mechanisms of Marburg virus gene expression	5R01AI133486-02	3
2019	Deciphering the pathogenic potential of Lloviu virus, a novel filovirus	5R21AI137793-02	2
2019	Integrated Support Services Core	5UC7AI095321-06-8669	1
2018	The role of TLR4 signaling in the pathogenesis of filovirus infection	1R21AI135912-01A1	2

Showing 10 of 26 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Mithal A, Hume AJ, Lindstrom-Vautrin J, Villacorta-Martin C, Olejnik J, Bullitt E, Hinds A, Mühlberger E, Mostoslavsky G. Human Pluripotent Stem Cell-Derived Intestinal Organoids Model SARS-CoV-2 Infection Revealing a Common Epithelial Inflammatory Response. Stem Cell Reports. 2021 04 13; 16(4):940-953.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Bullitt, Esther
Mostoslavsky, Gustavo
Olejnik, Judith

PMID: 33852884; PMCID: PMC8042780; DOI: 10.1016/j.stemcr.2021.02.019;

Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2021 Jan 07; 81(1):212.View Related Profiles. PMID: 33417854; PMCID: PMC7831449; DOI: 10.1016/j.molcel.2020.12.028;

Luban J, Sattler RA, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz SW. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines. Virus Res. 2021 01 15; 292:198246. PMID: 33249060; PMCID: PMC7690341; DOI: 10.1016/j.virusres.2020.198246;

Hekman RM, Hume AJ, Goel RK, Abo KM, Huang J, Blum BC, Werder RB, Suder EL, Paul I, Phanse S, Youssef A, Alysandratos KD, Padhorny D, Ojha S, Mora-Martin A, Kretov D, Ash PEA, Verma M, Zhao J, Patten JJ, Villacorta-Martin C, Bolzan D, Perea-Resa C, Bullitt E, Hinds A, Tilston-Lunel A, Varelas X, Farhangmehr S, Braunschweig U, Kwan JH, McComb M, Basu A, Saeed M, Perissi V, Burks EJ, Layne MD, Connor JH, Davey R, Cheng JX, Wolozin BL, Blencowe BJ, Wuchty S, Lyons SM, Kozakov D, Cifuentes D, Blower M, Kotton DN, Wilson AA, Mühlberger E, Emili A. Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2. Mol Cell. 2020 12 17; 80(6):1104-1122.e9.View Related Profiles. PMID: 33259812; PMCID: PMC7674017; DOI: 10.1016/j.molcel.2020.11.028;

Knipe DM, Levy O, Fitzgerald KA, Mühlberger E. Ensuring vaccine safety. Science. 2020 12 11; 370(6522):1274-1275. PMID: 33203781

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 12 03; 27(6):962-973.e7.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Burks, Eric
Bullitt, Esther
Hawkins, Finn
Huang, Jessie
Olejnik, Judith
Bosmann, Markus
Saeed, Mohsan
Werder, Rhiannon Bree

PMID: 32979316; PMCID: PMC7500949; DOI: 10.1016/j.stem.2020.09.013;

Kuhn JH, Adkins S, Alioto D, Alkhovsky SV, Amarasinghe GK, Anthony SJ, Avšic-Županc T, Ayllón MA, Bahl J, Balkema-Buschmann A, Ballinger MJ, Bartonicka T, Basler C, Bavari S, Beer M, Bente DA, Bergeron É, Bird BH, Blair C, Blasdell KR, Bradfute SB, Breyta R, Briese T, Brown PA, Buchholz UJ, Buchmeier MJ, Bukreyev A, Burt F, Buzkan N, Calisher CH, Cao M, Casas I, Chamberlain J, Chandran K, Charrel RN, Chen B, Chiumenti M, Choi IR, Clegg JCS, Crozier I, da Graça JV, Dal Bó E, Dávila AMR, de la Torre JC, de Lamballerie X, de Swart RL, Di Bello PL, Di Paola N, Di Serio F, Dietzgen RG, Digiaro M, Dolja VV, Dolnik O, Drebot MA, Drexler JF, Dürrwald R, Dufkova L, Dundon WG, Duprex WP, Dye JM, Easton AJ, Ebihara H, Elbeaino T, Ergünay K, Fernandes J, Fooks AR, Formenty PBH, Forth LF, Fouchier RAM, Freitas-Astúa J, Gago-Zachert S, Gao GF, García ML, García-Sastre A, Garrison AR, Gbakima A, Goldstein T, Gonzalez JJ, Griffiths A, Groschup MH, Günther S, Guterres A, Hall RA, Hammond J, Hassan M, Hepojoki J, Hepojoki S, Hetzel U, Hewson R, Hoffmann B, Hongo S, Höper D, Horie M, Hughes HR, Hyndman TH, Jambai A, Jardim R, Jiang D, Jin Q, Jonson GB, Junglen S, Karadag S, Keller KE, Klempa B, Klingström J, Kobinger G, Kondo H, Koonin EV, Krupovic M, Kurath G, Kuzmin IV, Laenen L, Lamb RA, Lambert AJ, Langevin SL, Lee B, Lemos ERS, Leroy EM, Li D, Li J, Liang M, Liú W, Liú Y, Lukashevich IS, Maes P, Marciel de Souza W, Marklewitz M, Marshall SH, Martelli GP, Martin RR, Marzano SL, Massart S, McCauley JW, Mielke-Ehret N, Minafra A, Minutolo M, Mirazimi A, Mühlbach HP, Mühlberger E, Naidu R, Natsuaki T, Navarro B, Navarro JA, Netesov SV, Neumann G, Nowotny N, Nunes MRT, Nylund A, Økland AL, Oliveira RC, Palacios G, Pallas V, Pályi B, Papa A, Parrish CR, Pauvolid-Corrêa A, Paweska JT, Payne S, Pérez DR, Pfaff F, Radoshitzky SR, Rahman AU, Ramos-González PL, Resende RO, Reyes CA, Rima BK, Romanowski V, Robles Luna G, Rota P, Rubbenstroth D, Runstadler JA, Ruzek D, Sabanadzovic S, Salát J, Sall AA, Salvato MS, Sarpkaya K, Sasaya T, Schwemmle M, Shabbir MZ, Shí X, Shí Z, Shirako Y, Simmonds P, Širmarová J, Sironi M, Smither S, Smura T, Song JW, Spann KM, Spengler JR, Stenglein MD, Stone DM, Straková P, Takada A, Tesh RB, Thornburg NJ, Tomonaga K, Tordo N, Towner JS, Turina M, Tzanetakis I, Ulrich RG, Vaira AM, van den Hoogen B, Varsani A, Vasilakis N, Verbeek M, Wahl V, Walker PJ, Wang H, Wang J, Wang X, Wang LF, Wèi T, Wells H, Whitfield AE, Williams JV, Wolf YI, Wú Z, Yang X, Yáng X, Yu X, Yutin N, Zerbini FM, Zhang T, Zhang YZ, Zhou G, Zhou X. 2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales. Arch Virol. 2020 Dec; 165(12):3023-3072.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke
Duprex, William

PMID: 32888050; PMCID: PMC7606449; DOI: 10.1007/s00705-020-04731-2;

Bruchez A, Sha K, Johnson J, Chen L, Stefani C, McConnell H, Gaucherand L, Prins R, Matreyek KA, Hume AJ, Mühlberger E, Schmidt EV, Olinger GG, Stuart LM, Lacy-Hulbert A. MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses. Science. 2020 10 09; 370(6513):241-247.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Olinger, Gene

PMID: 32855215; PMCID: PMC7665841; DOI: 10.1126/science.abb3753;

Luban J, Sattler R, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz S. The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. bioRxiv. 2020 Aug 05. PMID: 32793904; PMCID: PMC7418718; DOI: 10.1101/2020.08.05.238394;

Gao C, Zeng J, Jia N, Stavenhagen K, Matsumoto Y, Zhang H, Li J, Hume AJ, Mühlberger E, van Die I, Kwan J, Tantisira K, Emili A, Cummings RD. SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors. bioRxiv. 2020 Jul 30.View Related Profiles.

Hume, Adam
Emili, Andrew
Muhlberger, Elke

PMID: 32766577; PMCID: PMC7402034; DOI: 10.1101/2020.07.29.227462;

Showing 10 of 96 results. Show More

Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30.View Related Profiles.

Hume, Adam
Wilson, Andrew
Kotton, Darrell
Muhlberger, Elke
Burks, Eric
Bullitt, Esther
Hawkins, Finn
Olejnik, Judith
Bosmann, Markus
Saeed, Mohsan
Werder, Rhiannon Bree

PMID: 32637964; PMCID: PMC7337394; DOI: 10.1101/2020.06.30.175695;

Amraie R, Napoleon MA, Yin W, Berrigan J, Suder E, Zhao G, Olejnik J, Gummuluru S, Muhlberger E, Chitalia V, Rahimi N. CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells. bioRxiv. 2020 Jun 23.View Related Profiles.

Costello, Catherine
Xia, Chaoshuang
Muhlberger, Elke
Olejnik, Judith
Rahimi, Nader
Zhao, Qing
Gummuluru, Suryaram
Chitalia, Vipul
Yin, Wenqing

PMID: 32607506; PMCID: PMC7325172; DOI: 10.1101/2020.06.22.165803;

Pavlovich SS, Darling T, Hume AJ, Davey RA, Feng F, Mühlberger E, Kepler TB. Egyptian Rousette IFN-? Subtypes Elicit Distinct Antiviral Effects and Transcriptional Responses in Conspecific Cells. Front Immunol. 2020; 11:435.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Feng, Feng
Davey, Robert
Kepler, Thomas

PMID: 32231668; PMCID: PMC7083018; DOI: 10.3389/fimmu.2020.00435;

Amarasinghe GK, Ayllón MA, Bào Y, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chabi-Jesus C, Chandran K, Chiapponi C, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Griffiths A, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lavazza A, Lee B, Lelli D, Leroy EM, Li J, Maes P, Marzano SL, Moreno A, Mühlberger E, Netesov SV, Nowotny N, Nylund A, Økland AL, Palacios G, Pályi B, Paweska JT, Payne SL, Prosperi A, Ramos-González PL, Rima BK, Rota P, Rubbenstroth D, Shi M, Simmonds P, Smither SJ, Sozzi E, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang LF, Whitfield AE, Williams JV, Zerbini FM, Zhang T, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2019. Arch Virol. 2019 Jul; 164(7):1967-1980.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke
Duprex, William

PMID: 31089958; PMCID: PMC6641539; DOI: 10.1007/s00705-019-04247-4;

Hume AJ, Mühlberger E. Distinct Genome Replication and Transcription Strategies within the Growing Filovirus Family. J Mol Biol. 2019 10 04; 431(21):4290-4320.View Related Profiles.

Hume, Adam
Muhlberger, Elke

PMID: 31260690; PMCID: PMC6879820; DOI: 10.1016/j.jmb.2019.06.029;

Olejnik J, Mühlberger E, Hume AJ. Recent advances in marburgvirus research. F1000Res. 2019; 8.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Olejnik, Judith

PMID: 31131088; PMCID: PMC6530603; DOI: 10.12688/f1000research.17573.1;

Kuhn JH, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Crozier I, Dolnik O, Dye JM, Formenty PBH, Griffiths A, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, Palacios G, Pályi B, Paweska JT, Smither SJ, Takada A, Towner JS, Wahl V, ICTV Report Consortium. ICTV Virus Taxonomy Profile: Filoviridae. J Gen Virol. 2019 06; 100(6):911-912.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke

PMID: 31021739; PMCID: PMC7011696; DOI: 10.1099/jgv.0.001252;

Deflubé LR, Cressey TN, Hume AJ, Olejnik J, Haddock E, Feldmann F, Ebihara H, Fearns R, Mühlberger E. Ebolavirus polymerase uses an unconventional genome replication mechanism. Proc Natl Acad Sci U S A. 2019 04 23; 116(17):8535-8543.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Olejnik, Judith
Deflube, Laure
Fearns, Rachel

PMID: 30962389; PMCID: PMC6486738; DOI: 10.1073/pnas.1815745116;

Maes P, Amarasinghe GK, Ayllón MA, Basler CF, Bavari S, Blasdell KR, Briese T, Brown PA, Bukreyev A, Balkema-Buschmann A, Buchholz UJ, Chandran K, Crozier I, de Swart RL, Dietzgen RG, Dolnik O, Domier LL, Drexler JF, Dürrwald R, Dundon WG, Duprex WP, Dye JM, Easton AJ, Fooks AR, Formenty PBH, Fouchier RAM, Freitas-Astúa J, Ghedin E, Griffiths A, Hewson R, Horie M, Hurwitz JL, Hyndman TH, Jiang D, Kobinger GP, Kondo H, Kurath G, Kuzmin IV, Lamb RA, Lee B, Leroy EM, Li J, Marzano SL, Mühlberger E, Netesov SV, Nowotny N, Palacios G, Pályi B, Paweska JT, Payne SL, Rima BK, Rota P, Rubbenstroth D, Simmonds P, Smither SJ, Song Q, Song T, Spann K, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, van den Hoogen B, Vasilakis N, Wahl V, Walker PJ, Wang D, Wang LF, Whitfield AE, Williams JV, Yè G, Zerbini FM, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: second update 2018. Arch Virol. 2019 Apr; 164(4):1233-1244.View Related Profiles.

Griffiths, Anthony
Muhlberger, Elke
Duprex, William

PMID: 30663023; PMCID: PMC6460460; DOI: 10.1007/s00705-018-04126-4;

Olejnik J, Hume AJ, Mühlberger E. Toll-like receptor 4 in acute viral infection: Too much of a good thing. PLoS Pathog. 2018 12; 14(12):e1007390.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Olejnik, Judith

PMID: 30571771; PMCID: PMC6301565; DOI: 10.1371/journal.ppat.1007390;

Hume A, Mühlberger E. Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner. J Infect Dis. 2018 11 22; 218(suppl_5):S403-S408.View Related Profiles.

Hume, Adam
Muhlberger, Elke

PMID: 30165526; PMCID: PMC6249588; DOI: 10.1093/infdis/jiy473;

Olsen ME, Cressey TN, Mühlberger E, Connor JH. Differential Mechanisms for the Involvement of Polyamines and Hypusinated eIF5A in Ebola Virus Gene Expression. J Virol. 2018 10 15; 92(20).View Related Profiles.

Muhlberger, Elke
Connor, John

PMID: 30045993; PMCID: PMC6158423; DOI: 10.1128/JVI.01260-18;

Manhart WA, Pacheco JR, Hume AJ, Cressey TN, Deflubé LR, Mühlberger E. A Chimeric Lloviu Virus Minigenome System Reveals that the Bat-Derived Filovirus Replicates More Similarly to Ebolaviruses than Marburgviruses. Cell Rep. 2018 09 04; 24(10):2573-2580.e4.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Deflube, Laure

PMID: 30184492; PMCID: PMC6159894; DOI: 10.1016/j.celrep.2018.08.008;

Pavlovich SS, Lovett SP, Koroleva G, Guito JC, Arnold CE, Nagle ER, Kulcsar K, Lee A, Thibaud-Nissen F, Hume AJ, Mühlberger E, Uebelhoer LS, Towner JS, Rabadan R, Sanchez-Lockhart M, Kepler TB, Palacios G. The Egyptian Rousette Genome Reveals Unexpected Features of Bat Antiviral Immunity. Cell. 2018 05 17; 173(5):1098-1110.e18.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Kepler, Thomas

PMID: 29706541; PMCID: PMC7112298; DOI: 10.1016/j.cell.2018.03.070;

Amarasinghe GK, Aréchiga Ceballos NG, Banyard AC, Basler CF, Bavari S, Bennett AJ, Blasdell KR, Briese T, Bukreyev A, Caì Y, Calisher CH, Campos Lawson C, Chandran K, Chapman CA, Chiu CY, Choi KS, Collins PL, Dietzgen RG, Dolja VV, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Echevarría JE, Fooks AR, Formenty PBH, Fouchier RAM, Freuling CM, Ghedin E, Goldberg TL, Hewson R, Horie M, Hyndman TH, Jiang D, Kityo R, Kobinger GP, Kondo H, Koonin EV, Krupovic M, Kurath G, Lamb RA, Lee B, Leroy EM, Maes P, Maisner A, Marston DA, Mor SK, Müller T, Mühlberger E, Ramírez VMN, Netesov SV, Ng TFF, Nowotny N, Palacios G, Patterson JL, Paweska JT, Payne SL, Prieto K, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Siddell S, Smither SJ, Song Q, Song T, Stenglein MD, Stone DM, Takada A, Tesh RB, Thomazelli LM, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Vázquez-Morón S, Verdugo C, Volchkov VE, Wahl V, Walker PJ, Wang D, Wang LF, Wellehan JFX, Wiley MR, Whitfield AE, Wolf YI, Yè G, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2018. Arch Virol. 2018 Aug; 163(8):2283-2294. PMID: 29637429; PMCID: PMC6076851; DOI: 10.1007/s00705-018-3814-x;

McElroy AK, Mühlberger E, Muñoz-Fontela C. Immune barriers of Ebola virus infection. Curr Opin Virol. 2018 02; 28:152-160. PMID: 29452995; PMCID: PMC5886007; DOI: 10.1016/j.coviro.2018.01.010;

Nelson EV, Pacheco JR, Hume AJ, Cressey TN, Deflubé LR, Ruedas JB, Connor JH, Ebihara H, Mühlberger E. An RNA polymerase II-driven Ebola virus minigenome system as an advanced tool for antiviral drug screening. Antiviral Res. 2017 Oct; 146:21-27.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Nelson, Emily
Connor, John
Deflube, Laure

PMID: 28807685; PMCID: PMC5654650; DOI: 10.1016/j.antiviral.2017.08.005;

Olejnik J, Forero A, Deflubé LR, Hume AJ, Manhart WA, Nishida A, Marzi A, Katze MG, Ebihara H, Rasmussen AL, Mühlberger E. Ebolaviruses Associated with Differential Pathogenicity Induce Distinct Host Responses in Human Macrophages. J Virol. 2017 Jun 01; 91(11).View Related Profiles.

Hume, Adam
Muhlberger, Elke
Olejnik, Judith
Deflube, Laure

PMID: 28331091; PMCID: PMC5432886; DOI: 10.1128/JVI.00179-17;

Bào Y, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Dolnik O, Dye JM, Ebihara H, Formenty P, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, Patterson JL, Paweska JT, Smither SJ, Takada A, Towner JS, Volchkov VE, Wahl-Jensen V, Kuhn JH. Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses. Viruses. 2017 May 11; 9(5). PMID: 28492506; PMCID: PMC5454419; DOI: 10.3390/v9050106;

Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RAM, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiang D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH. Taxonomy of the order Mononegavirales: update 2017. Arch Virol. 2017 Aug; 162(8):2493-2504. PMID: 28389807; PMCID: PMC5831667; DOI: 10.1007/s00705-017-3311-7;

Olejnik J, Hume AJ, Leung DW, Amarasinghe GK, Basler CF, Mühlberger E. Filovirus Strategies to Escape Antiviral Responses. Curr Top Microbiol Immunol. 2017; 411:293-322.View Related Profiles.

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Muhlberger, Elke
Olejnik, Judith

PMID: 28685291; PMCID: PMC5973841; DOI: 10.1007/82_2017_13;

Brauburger K, Cressey T, Mühlberger E. Nonradioactive Northern Blot Analysis to Detect Ebola Virus Minigenomic mRNA. Methods Mol Biol. 2017; 1628:143-159.View Related Profiles.

Muhlberger, Elke
Brauburger, Kristina

PMID: 28573617

Cressey T, Brauburger K, Mühlberger E. Modeling Ebola Virus Genome Replication and Transcription with Minigenome Systems. Methods Mol Biol. 2017; 1628:79-92.View Related Profiles.

Muhlberger, Elke
Brauburger, Kristina

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Nelson EV, Schmidt KM, Deflubé LR, Doganay S, Banadyga L, Olejnik J, Hume AJ, Ryabchikova E, Ebihara H, Kedersha N, Ha T, Mühlberger E. Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol. 2016 Aug 15; 90(16):7268-84.View Related Profiles.

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PMID: 27252530; PMCID: PMC4984654; DOI: 10.1128/JVI.00459-16;

Hume AJ, Ames J, Rennick LJ, Duprex WP, Marzi A, Tonkiss J, Mühlberger E. Inactivation of RNA Viruses by Gamma Irradiation: A Study on Mitigating Factors. Viruses. 2016 Jul 22; 8(7).View Related Profiles.

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PMID: 27455307; PMCID: PMC4974539; DOI: 10.3390/v8070204;

Wilson MR, Fedewa G, Stenglein MD, Olejnik J, Rennick LJ, Nambulli S, Feldmann F, Duprex WP, Connor JH, Mühlberger E, DeRisi JL. Multiplexed Metagenomic Deep Sequencing To Analyze the Composition of High-Priority Pathogen Reagents. mSystems. 2016 Jul-Aug; 1(4).View Related Profiles.

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PMID: 27822544; PMCID: PMC5069959; DOI: 10.1128/mSystems.00058-16;

Schmidt KM, Mühlberger E. Marburg Virus Reverse Genetics Systems. Viruses. 2016 Jun 22; 8(6).View Related Profiles.

Muhlberger, Elke
Schmidt, Kristina

PMID: 27338448; PMCID: PMC4926198; DOI: 10.3390/v8060178;

Afonso CL, Amarasinghe GK, Bányai K, Bào Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Chéng J, Clawson AN, Collins PL, Dietzgen RG, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Farkas SL, Freitas-Astúa J, Formenty P, Fouchier RA, Fù Y, Ghedin E, Goodin MM, Hewson R, Horie M, Hyndman TH, Jiang D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lenardon S, Leroy EM, Li CX, Lin XD, Liú L, Longdon B, Marton S, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Randall RE, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Shi M, Smither SJ, Stenglein MD, Stone DM, Takada A, Terregino C, Tesh RB, Tian JH, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Verbeek M, Volchkov VE, Wahl-Jensen V, Walsh JA, Walker PJ, Wang D, Wang LF, Wetzel T, Whitfield AE, Xiè JT, Yuen KY, Zhang YZ, Kuhn JH. Taxonomy of the order Mononegavirales: update 2016. Arch Virol. 2016 Aug; 161(8):2351-60. PMID: 27216929; PMCID: PMC4947412; DOI: 10.1007/s00705-016-2880-1;

Brauburger K, Boehmann Y, Krähling V, Mühlberger E. Transcriptional Regulation in Ebola Virus: Effects of Gene Border Structure and Regulatory Elements on Gene Expression and Polymerase Scanning Behavior. J Virol. 2016 Feb; 90(4):1898-909.View Related Profiles.

Muhlberger, Elke
Brauburger, Kristina

PMID: 26656691; PMCID: PMC4733972; DOI: 10.1128/JVI.02341-15;

Pinto AK, Williams GD, Szretter KJ, White JP, Proença-Módena JL, Liu G, Olejnik J, Brien JD, Ebihara H, Mühlberger E, Amarasinghe G, Diamond MS, Boon AC. Human and Murine IFIT1 Proteins Do Not Restrict Infection of Negative-Sense RNA Viruses of the Orthomyxoviridae, Bunyaviridae, and Filoviridae Families. J Virol. 2015 Sep; 89(18):9465-76.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith

PMID: 26157117; PMCID: PMC4542382; DOI: 10.1128/JVI.00996-15;

Kuhn JH, Andersen KG, Bào Y, Bavari S, Becker S, Bennett RS, Bergman NH, Blinkova O, Bradfute S, Brister JR, Bukreyev A, Chandran K, Chepurnov AA, Davey RA, Dietzgen RG, Doggett NA, Dolnik O, Dye JM, Enterlein S, Fenimore PW, Formenty P, Freiberg AN, Garry RF, Garza NL, Gire SK, Gonzalez JP, Griffiths A, Happi CT, Hensley LE, Herbert AS, Hevey MC, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson JC, Johnson KM, Kindrachuk J, Klenk HD, Kobinger G, Kochel TJ, Lackemeyer MG, Lackner DF, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Omilabu SA, Palacios G, Panchal RG, Park DJ, Patterson JL, Paweska JT, Peters CJ, Pettitt J, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Sabeti PC, Sealfon R, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses. 2014 Sep; 6(9):3663-82.View Related Profiles.

Honko, Anna
Griffiths, Anthony
Muhlberger, Elke
Olinger, Gene
Davey, Robert

PMID: 25256396; PMCID: PMC4189044; DOI: 10.3390/v6093663;

Brauburger K, Boehmann Y, Tsuda Y, Hoenen T, Olejnik J, Schümann M, Ebihara H, Mühlberger E. Analysis of the highly diverse gene borders in Ebola virus reveals a distinct mechanism of transcriptional regulation. J Virol. 2014 Nov; 88(21):12558-71.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Brauburger, Kristina

PMID: 25142600; PMCID: PMC4248908; DOI: 10.1128/JVI.01863-14;

Bukreyev AA, Chandran K, Dolnik O, Dye JM, Ebihara H, Leroy EM, Mühlberger E, Netesov SV, Patterson JL, Paweska JT, Saphire EO, Smither SJ, Takada A, Towner JS, Volchkov VE, Warren TK, Kuhn JH. Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013. Arch Virol. 2014 Apr; 159(4):821-30. PMID: 24122154; PMCID: PMC3984924; DOI: 10.1007/s00705-013-1846-9;

Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA. Arch Virol. 2014 May; 159(5):1229-37.View Related Profiles.

Honko, Anna
Muhlberger, Elke
Olinger, Gene
Brauburger, Kristina
Davey, Robert

PMID: 24190508; PMCID: PMC4010566; DOI: 10.1007/s00705-013-1877-2;

Gantke T, Boussouf S, Janzen J, Morrice NA, Howell S, Mühlberger E, Ley SC. Ebola virus VP35 induces high-level production of recombinant TPL-2-ABIN-2-NF-?B1 p105 complex in co-transfected HEK-293 cells. Biochem J. 2013 Jun 1; 452(2):359-65. PMID: 23557442; PMCID: PMC3727213; DOI: 10.1042/BJ20121873;

Trunschke M, Conrad D, Enterlein S, Olejnik J, Brauburger K, Mühlberger E. The L-VP35 and L-L interaction domains reside in the amino terminus of the Ebola virus L protein and are potential targets for antivirals. Virology. 2013 Jul 5; 441(2):135-45.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Brauburger, Kristina

PMID: 23582637; PMCID: PMC3773471; DOI: 10.1016/j.virol.2013.03.013;

Olejnik J, Alonso J, Schmidt KM, Yan Z, Wang W, Marzi A, Ebihara H, Yang J, Patterson JL, Ryabchikova E, Mühlberger E. Ebola virus does not block apoptotic signaling pathways. J Virol. 2013 May; 87(10):5384-96.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Schmidt, Kristina

PMID: 23468487; PMCID: PMC3648168; DOI: 10.1128/JVI.01461-12;

Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Lofts LL, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST. Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae. Arch Virol. 2013 Jun; 158(6):1425-32.View Related Profiles.

Honko, Anna
Muhlberger, Elke
Olinger, Gene
Davey, Robert

PMID: 23358612; PMCID: PMC3669655; DOI: 10.1007/s00705-012-1594-2;

Brauburger K, Hume AJ, Mühlberger E, Olejnik J. Forty-five years of Marburg virus research. Viruses. 2012 Oct; 4(10):1878-927.View Related Profiles.

Hume, Adam
Muhlberger, Elke
Olejnik, Judith
Brauburger, Kristina

PMID: 23202446; PMCID: PMC3497034; DOI: 10.3390/v4101878;

Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Hensley LE, Honko AN, Jahrling PB, Johnson KM, Kobinger G, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Saphire EO, Smither SJ, Swanepoel R, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Weidmann M, Nichol ST. Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae. Arch Virol. 2013 Jan; 158(1):301-11.View Related Profiles.

Honko, Anna
Muhlberger, Elke
Olinger, Gene
Davey, Robert

PMID: 23001720; PMCID: PMC3535543; DOI: 10.1007/s00705-012-1454-0;

Schmidt KM, Schümann M, Olejnik J, Krähling V, Mühlberger E. Recombinant Marburg virus expressing EGFP allows rapid screening of virus growth and real-time visualization of virus spread. J Infect Dis. 2011 Nov; 204 Suppl 3:S861-70.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Schmidt, Kristina

PMID: 21987762; PMCID: PMC3218667; DOI: 10.1093/infdis/jir308;

Olejnik J, Ryabchikova E, Corley RB, Mühlberger E. Intracellular events and cell fate in filovirus infection. Viruses. 2011 Aug; 3(8):1501-31.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Corley, Ronald

PMID: 21927676; PMCID: PMC3172725; DOI: 10.3390/v3081501;

Leung DW, Shabman RS, Farahbakhsh M, Prins KC, Borek DM, Wang T, Mühlberger E, Basler CF, Amarasinghe GK. Structural and functional characterization of Reston Ebola virus VP35 interferon inhibitory domain. J Mol Biol. 2010 Jun 11; 399(3):347-57. PMID: 20399790; PMCID: PMC2917615; DOI: 10.1016/j.jmb.2010.04.022;

Valmas C, Grosch MN, Schümann M, Olejnik J, Martinez O, Best SM, Krähling V, Basler CF, Mühlberger E. Marburg virus evades interferon responses by a mechanism distinct from ebola virus. PLoS Pathog. 2010 Jan; 6(1):e1000721.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith

PMID: 20084112; PMCID: PMC2799553; DOI: 10.1371/journal.ppat.1000721;

Pfefferle S, Krähling V, Ditt V, Grywna K, Mühlberger E, Drosten C. Reverse genetic characterization of the natural genomic deletion in SARS-Coronavirus strain Frankfurt-1 open reading frame 7b reveals an attenuating function of the 7b protein in-vitro and in-vivo. Virol J. 2009; 6:131. PMID: 19698190; PMCID: PMC2739521; DOI: 10.1186/1743-422X-6-131;

Schümann M, Gantke T, Mühlberger E. Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain. J Virol. 2009 Sep; 83(17):8993-7. PMID: 19515768; PMCID: PMC2738155; DOI: 10.1128/JVI.00523-09;

Zinzula L, Esposito F, Mühlberger E, Trunschke M, Conrad D, Piano D, Tramontano E. Purification and functional characterization of the full length recombinant Ebola virus VP35 protein expressed in E. coli. Protein Expr Purif. 2009 Jul; 66(1):113-9. PMID: 19233284; DOI: 10.1016/j.pep.2009.02.008;

Enterlein S, Schmidt KM, Schümann M, Conrad D, Krähling V, Olejnik J, Mühlberger E. The marburg virus 3' noncoding region structurally and functionally differs from that of ebola virus. J Virol. 2009 May; 83(9):4508-19.View Related Profiles.

Muhlberger, Elke
Olejnik, Judith
Schmidt, Kristina

PMID: 19225002; PMCID: PMC2668471; DOI: 10.1128/JVI.02429-08;

Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E. Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. J Virol. 2009 Mar; 83(5):2298-309. PMID: 19109397; PMCID: PMC2643707; DOI: 10.1128/JVI.01245-08;

Habjan M, Andersson I, Klingström J, Schümann M, Martin A, Zimmermann P, Wagner V, Pichlmair A, Schneider U, Mühlberger E, Mirazimi A, Weber F. Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. PLoS One. 2008; 3(4):e2032. PMID: 18446221; PMCID: PMC2323571; DOI: 10.1371/journal.pone.0002032;

Mühlberger E. Filovirus replication and transcription. Future Virol. 2007 Mar; 2(2):205-215. PMID: 24093048; PMCID: PMC3787895; DOI: 10.2217/17460794.2.2.205;

Petrosava, A., Konry, T., Cosnier, S., Trakht, I., Lutwama, J., Rwaguma, E., Cherpunov, A., Mühlberger, E., Lobel, L., and Marks, R. S. Development of a highly sensitive, field operable biosensor for serological studies of Ebola virus in central Africa. Sensors & Actuators. 2007; 122(B):578-586.

Petrosova A, Konry T, Cosnier S, Trakht I, Lutwama J, Rwaguma E, Chepurnov A, Mühlberger E, Lobel L, Marks RS. Development of a highly sensitive, field operable biosensor for serological studies of Ebola virus in central Africa. Sens Actuators B Chem. 2007 Mar 26; 122(2):578-586. PMID: 32288238; PMCID: PMC7125681; DOI: 10.1016/j.snb.2006.07.005;

Enterlein S, Warfield KL, Swenson DL, Stein DA, Smith JL, Gamble CS, Kroeker AD, Iversen PL, Bavari S, Mühlberger E. VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice. Antimicrob Agents Chemother. 2006 Mar; 50(3):984-93. PMID: 16495261; PMCID: PMC1426423; DOI: 10.1128/AAC.50.3.984-993.2006;

Kash JC, Mühlberger E, Carter V, Grosch M, Perwitasari O, Proll SC, Thomas MJ, Weber F, Klenk HD, Katze MG. Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence. J Virol. 2006 Mar; 80(6):3009-20. PMID: 16501110; PMCID: PMC1395418; DOI: 10.1128/JVI.80.6.3009-3020.2006;

Negrete OA, Wolf MC, Aguilar HC, Enterlein S, Wang W, Mühlberger E, Su SV, Bertolotti-Ciarlet A, Flick R, Lee B. Two key residues in ephrinB3 are critical for its use as an alternative receptor for Nipah virus. PLoS Pathog. 2006 Feb; 2(2):e7. PMID: 16477309; PMCID: PMC1361355; DOI: 10.1371/journal.ppat.0020007;

Enterlein S, Volchkov V, Weik M, Kolesnikova L, Volchkova V, Klenk HD, Mühlberger E. Rescue of recombinant Marburg virus from cDNA is dependent on nucleocapsid protein VP30. J Virol. 2006 Jan; 80(2):1038-43. PMID: 16379005; PMCID: PMC1346851; DOI: 10.1128/JVI.80.2.1038-1043.2006;

Weik M, Enterlein S, Schlenz K, Mühlberger E. The Ebola virus genomic replication promoter is bipartite and follows the rule of six. J Virol. 2005 Aug; 79(16):10660-71. PMID: 16051858; PMCID: PMC1182658; DOI: 10.1128/JVI.79.16.10660-10671.2005;

Boehmann Y, Enterlein S, Randolf A, Mühlberger E. A reconstituted replication and transcription system for Ebola virus Reston and comparison with Ebola virus Zaire. Virology. 2005 Feb 5; 332(1):406-17. PMID: 15661171

Spiegel M, Pichlmair A, Mühlberger E, Haller O, Weber F. The antiviral effect of interferon-beta against SARS-coronavirus is not mediated by MxA protein. J Clin Virol. 2004 Jul; 30(3):211-3. PMID: 15135736

Weidmann M, Mühlberger E, Hufert FT. Rapid detection protocol for filoviruses. J Clin Virol. 2004 May; 30(1):94-9. PMID: 15072761

Hartlieb B, Modrof J, Mühlberger E, Klenk HD, Becker S. Oligomerization of Ebola virus VP30 is essential for viral transcription and can be inhibited by a synthetic peptide. J Biol Chem. 2003 Oct 24; 278(43):41830-6. PMID: 12912982

Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A. The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3. J Virol. 2003 Jul; 77(14):7945-56. PMID: 12829834; PMCID: PMC161945

Modrof J, Becker S, Mühlberger E. Ebola virus transcription activator VP30 is a zinc-binding protein. J Virol. 2003 Mar; 77(5):3334-8. PMID: 12584359; PMCID: PMC149768

Weik M, Modrof J, Klenk HD, Becker S, Mühlberger E. Ebola virus VP30-mediated transcription is regulated by RNA secondary structure formation. J Virol. 2002 Sep; 76(17):8532-9. PMID: 12163572; PMCID: PMC136988

Modrof J, Mühlberger E, Klenk HD, Becker S. Phosphorylation of VP30 impairs ebola virus transcription. J Biol Chem. 2002 Sep 6; 277(36):33099-104. PMID: 12052831

Sänger C, Mühlberger E, Lötfering B, Klenk HD, Becker S. The Marburg virus surface protein GP is phosphorylated at its ectodomain. Virology. 2002 Mar 30; 295(1):20-9. PMID: 12033762

Cheusova TB, Becker S, Muehlberger E, Riabchikova EI. [Submicroscopic characteristics of Marburg virus and its mini genome analog replication in cell cultures]. Mol Gen Mikrobiol Virusol. 2002; (2):27-30. PMID: 12180021

Modrof J, Möritz C, Kolesnikova L, Konakova T, Hartlieb B, Randolf A, Mühlberger E, Becker S. Phosphorylation of Marburg virus VP30 at serines 40 and 42 is critical for its interaction with NP inclusions. Virology. 2001 Aug 15; 287(1):171-82. PMID: 11504552

Sänger C, Mühlberger E, Ryabchikova E, Kolesnikova L, Klenk HD, Becker S. Sorting of Marburg virus surface protein and virus release take place at opposite surfaces of infected polarized epithelial cells. J Virol. 2001 Feb; 75(3):1274-83. PMID: 11152500; PMCID: PMC114033

Volchkov VE, Volchkova VA, Muhlberger E, Kolesnikova LV, Weik M, Dolnik O, Klenk HD. Recovery of infectious Ebola virus from complementary DNA: RNA editing of the GP gene and viral cytotoxicity. Science. 2001 Mar 9; 291(5510):1965-9. PMID: 11239157

Sänger C, Mühlberger E, Klenk HD, Becker S. Adverse effects of MVA-T7 on the transport of Marburg virus glycoprotein. J Virol Methods. 2001 Jan; 91(1):29-35. PMID: 11164483

Basler CF, Wang X, Mühlberger E, Volchkov V, Paragas J, Klenk HD, García-Sastre A, Palese P. The Ebola virus VP35 protein functions as a type I IFN antagonist. Proc Natl Acad Sci U S A. 2000 Oct 24; 97(22):12289-94. PMID: 11027311; PMCID: PMC17334

Kolesnikova L, Mühlberger E, Ryabchikova E, Becker S. Ultrastructural organization of recombinant Marburg virus nucleoprotein: comparison with Marburg virus inclusions. J Virol. 2000 Apr; 74(8):3899-904. PMID: 10729166; PMCID: PMC111900

Kedees MH, Gerold P, Azzouz N, Blaschke T, Shams-Eldin H, Mühlberger E, Holder AA, Klenk HD, Schwarz RT, Eckert V. Processing and localisation of a GPI-anchored Plasmodium falciparum surface protein expressed by the baculovirus system. Eur J Cell Biol. 2000 Jan; 79(1):52-61. PMID: 10711426

Mühlberger E, Weik M, Volchkov VE, Klenk HD, Becker S. Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems. J Virol. 1999 Mar; 73(3):2333-42. PMID: 9971816; PMCID: PMC104478

Lötfering B, Mühlberger E, Tamura T, Klenk HD, Becker S. The nucleoprotein of Marburg virus is target for multiple cellular kinases. Virology. 1999 Mar 1; 255(1):50-62. PMID: 10049821

Becker S, Mühlberger E. Co- and posttranslational modifications and functions of Marburg virus proteins. Curr Top Microbiol Immunol. 1999; 235:23-34. PMID: 9893376

Mühlberger E, Lötfering B, Klenk HD, Becker S. Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes. J Virol. 1998 Nov; 72(11):8756-64. PMID: 9765419; PMCID: PMC110291

Becker S, Rinne C, Hofsäss U, Klenk HD, Mühlberger E. Interactions of Marburg virus nucleocapsid proteins. Virology. 1998 Sep 30; 249(2):406-17. PMID: 9791031

Becker S, Klenk HD, Mühlberger E. Intracellular transport and processing of the Marburg virus surface protein in vertebrate and insect cells. Virology. 1996 Nov 1; 225(1):145-55. PMID: 8918541

Mühlberger E, Trommer S, Funke C, Volchkov V, Klenk HD, Becker S. Termini of all mRNA species of Marburg virus: sequence and secondary structure. Virology. 1996 Sep 15; 223(2):376-80. PMID: 8806574

Funke C, Becker S, Dartsch H, Klenk HD, Mühlberger E. Acylation of the Marburg virus glycoprotein. Virology. 1995 Apr 1; 208(1):289-97. PMID: 11831710

Will C, Mühlberger E, Linder D, Slenczka W, Klenk HD, Feldmann H. Marburg virus gene 4 encodes the virion membrane protein, a type I transmembrane glycoprotein. J Virol. 1993 Mar; 67(3):1203-10. PMID: 8437211; PMCID: PMC237485

Feldmann H, Mühlberger E, Randolf A, Will C, Kiley MP, Sanchez A, Klenk HD. Marburg virus, a filovirus: messenger RNAs, gene order, and regulatory elements of the replication cycle. Virus Res. 1992 Jun; 24(1):1-19. PMID: 1626422

Mühlberger E, Sanchez A, Randolf A, Will C, Kiley MP, Klenk HD, Feldmann H. The nucleotide sequence of the L gene of Marburg virus, a filovirus: homologies with paramyxoviruses and rhabdoviruses. Virology. 1992 Apr; 187(2):534-47. PMID: 1546452

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 96 publications over 28 distinct years, with a maximum of 11 publications in 2020