Keywords
Last Name

Hisashi Akiyama

TitleResearch Assistant Professor
InstitutionBoston University School of Medicine
DepartmentMicrobiology
Address72 E. Concord St Housman (R)
Boston MA 02118
Phone(617) 414-8077
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kijewski SD, Akiyama H, Feizpour A, Miller CM, Ramirez NG, Reinhard BM, Gummuluru S. Access of HIV-2 to CD169-dependent dendritic cell-mediated trans infection pathway is attenuated. Virology. 2016 Oct; 497:328-36. PMID: 27521724.
    View in: PubMed
  2. Yu X, Xu F, Ramirez NG, Kijewski SD, Akiyama H, Gummuluru S, Reinhard BM. Dressing up Nanoparticles: A Membrane Wrap to Induce Formation of the Virological Synapse. ACS Nano. 2015; 9(4):4182-92. PMID: 25853367.
    View in: PubMed
  3. Akiyama H, Ramirez NG, Gudheti MV, Gummuluru S. CD169-mediated trafficking of HIV to plasma membrane invaginations in dendritic cells attenuates efficacy of anti-gp120 broadly neutralizing antibodies. PLoS Pathog. 2015 Mar; 11(3):e1004751. PMID: 25760631.
    View in: PubMed
  4. Gummuluru S, Pina Ramirez NG, Akiyama H. CD169-dependent cell-associated HIV-1 transmission: a driver of virus dissemination. J Infect Dis. 2014 Dec 15; 210 Suppl 3:S641-7. PMID: 25414418.
    View in: PubMed
  5. Feizpour A, Yu X, Akiyama H, Miller CM, Edmans E, Gummuluru S, Reinhard BM. Quantifying lipid contents in enveloped virus particles with plasmonic nanoparticles. Small. 2015 Apr; 11(13):1592-602. PMID: 25382201.
    View in: PubMed
  6. Yu X, Feizpour A, Ramirez NG, Wu L, Akiyama H, Xu F, Gummuluru S, Reinhard BM. Glycosphingolipid-functionalized nanoparticles recapitulate CD169-dependent HIV-1 uptake and trafficking in dendritic cells. Nat Commun. 2014; 5:4136. PMID: 24947940.
    View in: PubMed
  7. Akiyama H, Miller C, Patel HV, Hatch SC, Archer J, Ramirez NG, Gummuluru S. Virus particle release from glycosphingolipid-enriched microdomains is essential for dendritic cell-mediated capture and transfer of HIV-1 and henipavirus. J Virol. 2014 Aug; 88(16):8813-25. PMID: 24872578.
    View in: PubMed
  8. Puryear WB, Akiyama H, Geer SD, Ramirez NP, Yu X, Reinhard BM, Gummuluru S. Interferon-inducible mechanism of dendritic cell-mediated HIV-1 dissemination is dependent on Siglec-1/CD169. PLoS Pathog. 2013; 9(4):e1003291. PMID: 23593001.
    View in: PubMed
  9. Schiralli Lester GM, Akiyama H, Evans E, Singh J, Gummuluru S, Henderson AJ. Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization. Virology. 2013 Feb 5; 436(1):235-43. PMID: 23260110.
    View in: PubMed
  10. Sagar M, Akiyama H, Etemad B, Ramirez N, Freitas I, Gummuluru S. Transmembrane domain membrane proximal external region but not surface unit-directed broadly neutralizing HIV-1 antibodies can restrict dendritic cell-mediated HIV-1 trans-infection. J Infect Dis. 2012 Apr 15; 205(8):1248-57. PMID: 22396600.
    View in: PubMed
  11. Müller B, Anders M, Akiyama H, Welsch S, Glass B, Nikovics K, Clavel F, Tervo HM, Keppler OT, Kräusslich HG. HIV-1 Gag processing intermediates trans-dominantly interfere with HIV-1 infectivity. J Biol Chem. 2009 Oct 23; 284(43):29692-703. PMID: 19666477.
    View in: PubMed
  12. Lorizate M, Brügger B, Akiyama H, Glass B, Müller B, Anderluh G, Wieland FT, Kräusslich HG. Probing HIV-1 membrane liquid order by Laurdan staining reveals producer cell-dependent differences. J Biol Chem. 2009 Aug 14; 284(33):22238-47. PMID: 19553682.
    View in: PubMed
  13. Akiyama H, Ishimatsu M, Miura T, Hayami M, Ido E. Construction and infection of a new simian/human immunodeficiency chimeric virus (SHIV) containing the integrase gene of the human immunodeficiency virus type 1 genome and analysis of its adaptation to monkey cells. Microbes Infect. 2008 Apr; 10(5):531-9. PMID: 18403228.
    View in: PubMed
  14. Ishimatsu M, Suzuki H, Akiyama H, Miura T, Hayami M, Ido E. Construction of a novel SHIV having an HIV-1-derived protease gene and its infection to rhesus macaques: a useful tool for in vivo efficacy tests of protease inhibitors. Microbes Infect. 2007 Apr; 9(4):475-82. PMID: 17350308.
    View in: PubMed
  15. Yoshimura K, Ido E, Akiyama H, Kimura T, Aoki M, Suzuki H, Mitsuya H, Hayami M, Matsushita S. The impact of highly active antiretroviral therapy by the oral route on the CD8 subset in monkeys infected chronically with SHIV 89.6P. J Virol Methods. 2003 Sep; 112(1-2):121-8. PMID: 12951220.
    View in: PubMed
  16. Akahata W, Ido E, Akiyama H, Uesaka H, Enose Y, Horiuchi R, Kuwata T, Goto T, Takahashi H, Hayami M. DNA vaccination of macaques by a full-genome simian/human immunodeficiency virus type 1 plasmid chimera that produces non-infectious virus particles. J Gen Virol. 2003 Aug; 84(Pt 8):2237-44. PMID: 12867656.
    View in: PubMed
  17. Akiyama H, Ido E, Akahata W, Kuwata T, Miura T, Hayami M. Construction and in vivo infection of a new simian/human immunodeficiency virus chimera containing the reverse transcriptase gene and the 3' half of the genomic region of human immunodeficiency virus type 1. J Gen Virol. 2003 Jul; 84(Pt 7):1663-9. PMID: 12810859.
    View in: PubMed
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