Keywords
Last Name

Shobini Jayaraman, MD, PhD

TitleResearch Scientist
InstitutionBoston University School of Medicine
DepartmentPhysiology & Biophysics
Address700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Phone(617) 638-4247
ORCID ORCID Icon0000-0003-1616-5347
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Jayaraman S, Sánchez-Quesada JL, Gursky O. Triglyceride increase in the core of high-density lipoproteins augments apolipoprotein dissociation from the surface: Potential implications for treatment of apolipoprotein deposition diseases. Biochim Biophys Acta. 2017 Jan; 1863(1):200-210. PMID: 27768903.
    View in: PubMed
  2. Jayaraman S, Haupt C, Gursky O. Paradoxical effects of SAA on lipoprotein oxidation suggest a new antioxidant function for SAA. J Lipid Res. 2016 Dec; 57(12):2138-2149. PMID: 27744369.
    View in: PubMed
  3. Rull A, Jayaraman S, Gantz DL, Rivas-Urbina A, Pérez-Cuellar M, Ordóñez-Llanos J, Sánchez-Quesada JL, Gursky O. Thermal stability of human plasma electronegative low-density lipoprotein: A paradoxical behavior of low-density lipoprotein aggregation. Biochim Biophys Acta. 2016 Sep; 1861(9 Pt A):1015-24. PMID: 27233433.
    View in: PubMed
  4. Jayaraman S, Haupt C, Gursky O. Thermal transitions in serum amyloid A in solution and on the lipid: implications for structure and stability of acute-phase HDL. J Lipid Res. 2015 Aug; 56(8):1531-42. PMID: 26022803.
    View in: PubMed
  5. Chan GK, Witkowski A, Gantz DL, Zhang TO, Zanni MT, Jayaraman S, Cavigiolio G. Myeloperoxidase-mediated Methionine Oxidation Promotes an Amyloidogenic Outcome for Apolipoprotein A-I. J Biol Chem. 2015 Apr 24; 290(17):10958-71. PMID: 25759391.
    View in: PubMed
  6. Das M, Mei X, Jayaraman S, Atkinson D, Gursky O. Amyloidogenic mutations in human apolipoprotein A-I are not necessarily destabilizing - a common mechanism of apolipoprotein A-I misfolding in familial amyloidosis and atherosclerosis. FEBS J. 2014 Jun; 281(11):2525-42. PMID: 24702826.
    View in: PubMed
  7. Cavigiolio G, Jayaraman S. Proteolysis of apolipoprotein A-I by secretory phospholipase A2: a new link between inflammation and atherosclerosis. J Biol Chem. 2014 Apr 4; 289(14):10011-23. PMID: 24523407.
    View in: PubMed
  8. Gao X, Yuan S, Jayaraman S, Gursky O. Role of apolipoprotein A-II in the structure and remodeling of human high-density lipoprotein (HDL): protein conformational ensemble on HDL. Biochemistry. 2012 Jun 12; 51(23):4633-41. PMID: 22631438.
    View in: PubMed
  9. Jayaraman S, Cavigiolio G, Gursky O. Folded functional lipid-poor apolipoprotein A-I obtained by heating of high-density lipoproteins: relevance to high-density lipoprotein biogenesis. Biochem J. 2012 Mar 15; 442(3):703-12. PMID: 22150513.
    View in: PubMed
  10. Jayaraman S, Abe-Dohmae S, Yokoyama S, Cavigiolio G. Impact of self-association on function of apolipoprotein A-I. J Biol Chem. 2011 Oct 14; 286(41):35610-23. PMID: 21835924.
    View in: PubMed
  11. Jayaraman S, Jasuja R, Zakharov MN, Gursky O. Pressure perturbation calorimetry of lipoproteins reveals an endothermic transition without detectable volume changes. Implications for adsorption of apolipoprotein to a phospholipid surface. Biochemistry. 2011 May 17; 50(19):3919-27. PMID: 21452855.
    View in: PubMed
  12. Jayaraman S, Gantz DL, Gursky O. Effects of phospholipase A(2) and its products on structural stability of human LDL: relevance to formation of LDL-derived lipid droplets. J Lipid Res. 2011 Mar; 52(3):549-57. PMID: 21220788.
    View in: PubMed
  13. Jayaraman S, Benjwal S, Gantz DL, Gursky O. Effects of cholesterol on thermal stability of discoidal high density lipoproteins. J Lipid Res. 2010 Feb; 51(2):324-33. PMID: 19700415.
    View in: PubMed
  14. Gao X, Yuan S, Jayaraman S, Gursky O. Differential stability of high-density lipoprotein subclasses: effects of particle size and protein composition. J Mol Biol. 2009 Apr 3; 387(3):628-38. PMID: 19236880.
    View in: PubMed
  15. Guha M, Gao X, Jayaraman S, Gursky O. Correlation of structural stability with functional remodeling of high-density lipoproteins: the importance of being disordered. Biochemistry. 2008 Nov 4; 47(44):11393-7. PMID: 18839964.
    View in: PubMed
  16. Jayaraman S, Gantz DL, Gursky O. Effects of protein oxidation on the structure and stability of model discoidal high-density lipoproteins. Biochemistry. 2008 Mar 25; 47(12):3875-82. PMID: 18302337.
    View in: PubMed
  17. Gao X, Jayaraman S, Gursky O. Mild oxidation promotes and advanced oxidation impairs remodeling of human high-density lipoprotein in vitro. J Mol Biol. 2008 Feb 29; 376(4):997-1007. PMID: 18190928.
    View in: PubMed
  18. Jayaraman S, Gantz DL, Gursky O. Effects of oxidation on the structure and stability of human low-density lipoprotein. Biochemistry. 2007 May 15; 46(19):5790-7. PMID: 17444660.
    View in: PubMed
  19. Benjwal S, Jayaraman S, Gursky O. Role of secondary structure in protein-phospholipid surface interactions: reconstitution and denaturation of apolipoprotein C-I:DMPC complexes. Biochemistry. 2007 Apr 3; 46(13):4184-94. PMID: 17341095.
    View in: PubMed
  20. Jayaraman S, Gantz DL, Gursky O. Effects of salt on the thermal stability of human plasma high-density lipoprotein. Biochemistry. 2006 Apr 11; 45(14):4620-8. PMID: 16584197.
    View in: PubMed
  21. Benjwal S, Jayaraman S, Gursky O. Electrostatic effects on the stability of discoidal high-density lipoproteins. Biochemistry. 2005 Aug 2; 44(30):10218-26. PMID: 16042399.
    View in: PubMed
  22. Jayaraman S, Gantz D, Gursky O. Structural basis for thermal stability of human low-density lipoprotein. Biochemistry. 2005 Mar 15; 44(10):3965-71. PMID: 15751972.
    View in: PubMed
  23. Jayaraman S, Gantz DL, Gursky O. Kinetic stabilization and fusion of apolipoprotein A-2:DMPC disks: comparison with apoA-1 and apoC-1. Biophys J. 2005 Apr; 88(4):2907-18. PMID: 15681655.
    View in: PubMed
  24. Jayaraman S, Gantz DL, Gursky O. Poly(ethylene glycol)-induced fusion and destabilization of human plasma high-density lipoproteins. Biochemistry. 2004 May 11; 43(18):5520-31. PMID: 15122918.
    View in: PubMed
  25. Crocker E, Patel AB, Eilers M, Jayaraman S, Getmanova E, Reeves PJ, Ziliox M, Khorana HG, Sheves M, Smith SO. Dipolar assisted rotational resonance NMR of tryptophan and tyrosine in rhodopsin. J Biomol NMR. 2004 May; 29(1):11-20. PMID: 15017136.
    View in: PubMed
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