Finn Hawkins, MBBCh
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MBBCh, National University of Ireland




Dr. Hawkins is a Principal Investigator (P.I.) in the Center for Regenerative Medicine and The Pulmonary Center. His research focus is studying human lung development and disease using human induced pluripotent stem cells (iPSCs). Dr. Hawkins is currently using iPSC technology to study airway biology with a focus on Cystic Fibrosis.

Member
Boston University
Pulmonary Center


Member
Boston University
Center for Regenerative Medicine


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences




Regenerating Airway Epithelium with Basal Cells Derived from Human iPSCs
02/01/2021 - 01/31/2024 (PI)
Cystic Fibrosis Foundation


iPSC-Derived Airway Basal Cells to Model Human Airway Development and Disease
09/01/2018 - 08/31/2023 (PI)
NIH/National Heart, Lung, and Blood Institute
5R01HL139799-03

De-Novo Generation of Pulmonary ionocytes from Human Pluripotent Stem Cells
11/01/2020 - 10/31/2022 (Multi-PI)
PI: Finn Hawkins, MBBCh
Cystic Fibrosis Foundation


Refining stage-specific patterning to efficiently generate basal cells from iPSCs
07/01/2019 - 07/31/2021 (PI)
Cystic Fibrosis Foundation


Generation of functional lung stem cells from human iPSCs
07/01/2019 - 06/30/2021 (Multi-PI)
PI: Finn Hawkins, MBBCh
NIH/National Heart, Lung, and Blood Institute
5U01HL148692-02

Creating the W1282X CFTR Airway Epithelial Cell Toolbox
07/03/2017 - 01/31/2020 (Subcontract PI)
University of North Carolina at Chapel Hill Emilys Entourage


Personalized Drug Predictions For CF Using iPSC-derived Bronchospheres
04/01/2017 - 03/31/2019 (PI)
Cystic Fibrosis Foundation


Personalized Assessment of CFTR Function in iPSC-derived Lung Organoids
01/01/2016 - 12/31/2016 (PI)
Cystic Fibrosis Foundation


Reconstructing Lung Epithelium with Gene-corrected Disease-specific iPS cells
07/01/2012 - 06/30/2014 (Co-Investigator)
PI: Darrell Nelson Kotton, MD
American Lung Association




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Suzuki S, Hawkins FJ, Barillà C, Beermann ML, Kotton DN, Davis BR. Differentiation of human pluripotent stem cells into functional airway basal stem cells. STAR Protoc. 2021 Sep 17; 2(3):100683.View Related Profiles. PMID: 34355203; PMCID: PMC8322461; DOI: 10.1016/j.xpro.2021.100683;
     
  2. Smyth R, Sloan JM, Burks E, Hawkins F. Primary pulmonary marginal zone lymphoma: an unusual cause of pulmonary infiltrates. Respirol Case Rep. 2021 Aug; 9(8):e00806.View Related Profiles. PMID: 34221408; PMCID: PMC8239556; DOI: 10.1002/rcr2.806;
     
  3. Hawkins FJ, Suzuki S, Beermann ML, Barillà C, Wang R, Villacorta-Martin C, Berical A, Jean JC, Le Suer J, Matte T, Simone-Roach C, Tang Y, Schlaeger TM, Crane AM, Matthias N, Huang SXL, Randell SH, Wu J, Spence JR, Carraro G, Stripp BR, Rab A, Sorsher EJ, Horani A, Brody SL, Davis BR, Kotton DN. Derivation of Airway Basal Stem Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2021 01 07; 28(1):79-95.e8.View Related Profiles. PMID: 33098807; PMCID: PMC7796997; DOI: 10.1016/j.stem.2020.09.017;
     
  4. Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Lindstrom-Vautrin J, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-Derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. Cell Stem Cell. 2020 12 03; 27(6):962-973.e7.View Related Profiles. PMID: 32979316; PMCID: PMC7500949; DOI: 10.1016/j.stem.2020.09.013;
     
  5. King NE, Suzuki S, Barillà C, Hawkins FJ, Randell SH, Reynolds SD, Stripp BR, Davis BR. Correction of Airway Stem Cells: Genome Editing Approaches for the Treatment of Cystic Fibrosis. Hum Gene Ther. 2020 09; 31(17-18):956-972. PMID: 32741223; PMCID: PMC7495916; DOI: 10.1089/hum.2020.160;
     
  6. Huang J, Hume AJ, Abo KM, Werder RB, Villacorta-Martin C, Alysandratos KD, Beermann ML, Simone-Roach C, Olejnik J, Suder EL, Bullitt E, Hinds A, Sharma A, Bosmann M, Wang R, Hawkins F, Burks EJ, Saeed M, Wilson AA, Mühlberger E, Kotton DN. SARS-CoV-2 Infection of Pluripotent Stem Cell-derived Human Lung Alveolar Type 2 Cells Elicits a Rapid Epithelial-Intrinsic Inflammatory Response. bioRxiv. 2020 Jun 30.View Related Profiles. PMID: 32637964; PMCID: PMC7337394; DOI: 10.1101/2020.06.30.175695;
     
  7. Abo KM, Ma L, Matte T, Huang J, Alysandratos KD, Werder RB, Mithal A, Beermann ML, Lindstrom-Vautrin J, Mostoslavsky G, Ikonomou L, Kotton DN, Hawkins F, Wilson A, Villacorta-Martin C. Human iPSC-derived alveolar and airway epithelial cells can be cultured at air-liquid interface and express SARS-CoV-2 host factors. bioRxiv. 2020 Jun 04.View Related Profiles. PMID: 32577635; PMCID: PMC7302183; DOI: 10.1101/2020.06.03.132639;
     
  8. Wang R, McCauley KB, Kotton DN, Hawkins F. Differentiation of human airway-organoids from induced pluripotent stem cells (iPSCs). Methods Cell Biol. 2020; 159:95-114.View Related Profiles. PMID: 32586451
     
  9. De Santi C, Fernández Fernández E, Gaul R, Vencken S, Glasgow A, Oglesby IK, Hurley K, Hawkins F, Mitash N, Mu F, Raoof R, Henshall DC, Cutrona MB, Simpson JC, Harvey BJ, Linnane B, McNally P, Cryan SA, MacLoughlin R, Swiatecka-Urban A, Greene CM. Precise Targeting of miRNA Sites Restores CFTR Activity in CF Bronchial Epithelial Cells. Mol Ther. 2020 04 08; 28(4):1190-1199. PMID: 32059764; PMCID: PMC7132615; DOI: 10.1016/j.ymthe.2020.02.001;
     
  10. Mithal A, Capilla A, Heinze D, Berical A, Villacorta-Martin C, Vedaie M, Jacob A, Abo K, Szymaniak A, Peasley M, Stuffer A, Mahoney J, Kotton DN, Hawkins F, Mostoslavsky G. Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells. Nat Commun. 2020 01 10; 11(1):215.View Related Profiles. PMID: 31924806; PMCID: PMC6954238; DOI: 10.1038/s41467-019-13916-6;
     
Showing 10 of 28 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 28 publications over 10 distinct years, with a maximum of 8 publications in 2020

YearPublications
20092
20101
20111
20121
20153
20174
20183
20193
20208
20212


Human Airway Basal Stem Cells Created from Patients’ Cells

Genetic Engineering & Biotechnology News: 10/27/2020

Patient-specific airway stem cells developed to model lung diseases

The Science Advisory Board 10/26/2020

What Sets Off Deadly Levels of Lung Inflammation in Some COVID-19 Patients?

BU Today 9/8/2020

Chasing a Cure for Lung Disease With Stem Cells: A Conversation With Finn Hawkins

HealthCity 7/2/2019
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