Katrina E. Traber, MD, PhD
Assistant Professor
Boston University School of Medicine
Dept of Medicine
Pulmonary, Allergy, Sleep & Critical Care Medicine

MD, New York University School of Medicine
PhD, New York University School of Medicine
MS, New York University School of Medicine

Pronouns: she/her/hers



The long-term goal of the Traber Lab is to identify and develop new strategies to treat severe neutrophil-based sequelae of pneumonia such as ARDS and sepsis. To achieve this goal, we use in vivo and in vitro models of pneumonia to investigate mechanisms of neutrophil dysfunction in acute lung infections. Currently, we have been using two broad approaches to understand neutrophil biology. First, we are examining modulation of the neutrophil transcriptome during neutrophil migration from circulation to the alveolar space. Second, we are investigating how Oncostatin M (OSM), an IL-6 family cytokine produced by neutrophils in many acute and chronic inflammatory settings, including pneumonia, ARDS and sepsis potentiates neutrophil migration to the alveoli during pneumonia.

If you are interested in joining our research group, please contact Dr. Traber at katraber@bu.edu.

Member
Boston University
Pulmonary Center


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




The Role of Oncostatin-M in Pneumonia
09/01/2016 - 09/30/2021 (PI)
NIH/National Heart, Lung, and Blood Institute
5K08HL130582-05

Distinct Roles of LIF and OSM During Pneumonia
07/01/2014 - 06/30/2015 (PI)
NIH/National Heart, Lung, and Blood Institute
1F32HL120551-01A1



Title

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Traber KE, Center DM. Toward a More Precise Solution to Asthma Therapy. Am J Respir Cell Mol Biol. 2021 09; 65(3):241-242.View Related Profiles. PMID: 34153196
     
  2. Odom CV, Kim Y, Burgess CL, Baird LA, Korkmaz FT, Na E, Shenoy AT, Arafa EI, Lam TT, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. Liver-Dependent Lung Remodeling during Systemic Inflammation Shapes Responses to Secondary Infection. J Immunol. 2021 Oct 01; 207(7):1891-1902.View Related Profiles. PMID: 34470857
     
  3. Traber KE, Dimbo EL, Shenoy AT, Symer EM, Allen E, Mizgerd JP, Quinton LJ. Neutrophil-Derived Oncostatin M Triggers Diverse Signaling Pathways during Pneumonia. Infect Immun. 2021 03 17; 89(4).View Related Profiles. PMID: 33526570; PMCID: PMC8090961; DOI: 10.1128/IAI.00655-20;
     
  4. Guillon A, Arafa EI, Barker KA, Belkina AC, Martin I, Shenoy AT, Wooten AK, Lyon De Ana C, Dai A, Labadorf A, Hernandez Escalante J, Dooms H, Blasco H, Traber KE, Jones MR, Quinton LJ, Mizgerd JP. Pneumonia recovery reprograms the alveolar macrophage pool. JCI Insight. 2020 02 27; 5(4).View Related Profiles. PMID: 31990682; PMCID: PMC7101156; DOI: 10.1172/jci.insight.133042;
     
  5. Traber KE, Dimbo EL, Symer EM, Korkmaz FT, Jones MR, Mizgerd JP, Quinton LJ. Roles of interleukin-11 during acute bacterial pneumonia. PLoS One. 2019; 14(8):e0221029.View Related Profiles. PMID: 31415618; PMCID: PMC6695241; DOI: 10.1371/journal.pone.0221029;
     
  6. Kim Y, Allen E, Baird LA, Symer EM, Korkmaz FT, Na E, Odom CV, Jones MR, Mizgerd JP, Traber KE, Quinton LJ. NF-?B RelA Is Required for Hepatoprotection during Pneumonia and Sepsis. Infect Immun. 2019 08; 87(8).View Related Profiles. PMID: 31160364; PMCID: PMC6652780; DOI: 10.1128/IAI.00132-19;
     
  7. Jacob A, Morley M, Hawkins F, McCauley KB, Jean JC, Heins H, Na CL, Weaver TE, Vedaie M, Hurley K, Hinds A, Russo SJ, Kook S, Zacharias W, Ochs M, Traber K, Quinton LJ, Crane A, Davis BR, White FV, Wambach J, Whitsett JA, Cole FS, Morrisey EE, Guttentag SH, Beers MF, Kotton DN. Differentiation of Human Pluripotent Stem Cells into Functional Lung Alveolar Epithelial Cells. Cell Stem Cell. 2017 Oct 05; 21(4):472-488.e10.View Related Profiles. PMID: 28965766; PMCID: PMC5755620; DOI: 10.1016/j.stem.2017.08.014;
     
  8. Traber KE, Symer EM, Allen E, Kim Y, Hilliard KL, Wasserman GA, Stewart CL, Jones MR, Mizgerd JP, Quinton LJ. Myeloid-epithelial cross talk coordinates synthesis of the tissue-protective cytokine leukemia inhibitory factor during pneumonia. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L548-L558.View Related Profiles. PMID: 28522567; PMCID: PMC5625259; DOI: 10.1152/ajplung.00482.2016;
     
  9. Traber KE, Hilliard KL, Allen E, Wasserman GA, Yamamoto K, Jones MR, Mizgerd JP, Quinton LJ. Induction of STAT3-Dependent CXCL5 Expression and Neutrophil Recruitment by Oncostatin-M during Pneumonia. Am J Respir Cell Mol Biol. 2015 Oct; 53(4):479-88.View Related Profiles. PMID: 25692402; PMCID: PMC4742898; DOI: 10.1165/rcmb.2014-0342OC;
     
  10. Hilliard KL, Allen E, Traber KE, Yamamoto K, Stauffer NM, Wasserman GA, Jones MR, Mizgerd JP, Quinton LJ. The Lung-Liver Axis: A Requirement for Maximal Innate Immunity and Hepatoprotection during Pneumonia. Am J Respir Cell Mol Biol. 2015 Sep; 53(3):378-90.View Related Profiles. PMID: 25607543; PMCID: PMC4566062; DOI: 10.1165/rcmb.2014-0195OC;
     
Showing 10 of 14 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 14 publications over 8 distinct years, with a maximum of 3 publications in 2015 and 2021

YearPublications
20051
20061
20081
20153
20172
20192
20201
20213


Available to Mentor as: (Review Mentor Role Definitions):
  • Advisor
  • Career Mentor
  • Co-Mentor or Peer Mentor
  • Education Mentor
  • Project Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:
  • Email (see 'Contact Info')

72 E. Concord St Housman (R)
Boston MA 02118
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