Saravanan Subramaniam, PhD
Research Assistant Professor
Boston University School of Medicine
Pulmonary Center

PhD, Justus Liebig Universitaet Giessen

Pronouns: he/him/his



Dr. Saravanan Subramaniam completed his bachelor and master degree in pharmacy and pharmacology from India and doctoral degree from Germany. He had completed his postdoctoral research at the center for thrombosis and hemostasis, Johannes Gutenberg University (Germany) and at McAllister Heart Institute, University of North Carolina (USA). He has published his research work in several high impact factor journals (Blood, circulation research, Hepatology, etc.,) and received several awards and travel grants. His area of specialization includes Intravital imaging of blood cells and coagulation.

2019 Early career award: International Society on Thrombosis and Haemostasis (ISTH 2019) AUSTRALIA
2018 Young Investigator Award: CSATVB-2018, Toronto, CANADA


Anti-complement therapy: a drug target for COVID-19-induced inflammation and coagulation
03/01/2021 - 02/28/2022 (PI)
Aniara Diagnostica




Title


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Subramaniam S, Ogoti Y, Hernandez I, Zogg M, Botros F, Burns R, DeRousse JT, Dockendorff C, Mackman N, Antoniak S, Fletcher C, Weiler H. A thrombin-PAR1/2 feedback loop amplifies thromboinflammatory endothelial responses to the viral RNA analogue poly(I:C). Blood Adv. 2021 07 13; 5(13):2760-2774. PMID: 34242391; DOI: 10.1182/bloodadvances.2021004360;
     
  2. Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2021 Jul 07.View Related Profiles. PMID: 34235728; DOI: 10.1111/bph.15587;
     
  3. Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. mBio. 2019 10 22; 10(5). PMID: 31641089; PMCID: PMC6805995; DOI: 10.1128/mBio.02298-19;
     
  4. Subramaniam S, Boukhlouf S, Fletcher C. A bacterial metabolite, trimethylamine N-oxide, disrupts the hemostasis balance in human primary endothelial cells but no coagulopathy in mice. Blood Coagul Fibrinolysis. 2019 Oct; 30(7):324-330. PMID: 31490208; DOI: 10.1097/MBC.0000000000000838;
     
  5. Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q. Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. Blood Adv. 2019 09 24; 3(18):2700-2711. PMID: 31515232; PMCID: PMC6759737; DOI: 10.1182/bloodadvances.2019000516;
     
  6. Gandhi DM, Rosas R, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C. The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability. Bioorg Med Chem. 2019 09 01; 27(17):3788-3796. PMID: 31320211; PMCID: PMC6706283; DOI: 10.1016/j.bmc.2019.06.043;
     
  7. Subramaniam S, Kanse SM, Kothari H, Reinhardt C, Fletcher C. Post-transcriptional, post-translational and pharmacological regulation of tissue factor pathway inhibitor. Blood Coagul Fibrinolysis. 2018 Dec; 29(8):668-682. PMID: 30439766
     
  8. Etscheid M, Subramaniam S, Lochnit G, Zabczyk M, Undas A, Lang IM, Hanschmann KM, Kanse SM. Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP). Biochim Biophys Acta Mol Basis Dis. 2018 10; 1864(10):3397-3406. PMID: 30076961; DOI: 10.1016/j.bbadis.2018.07.030;
     
  9. Bode MF, Auriemma AC, Grover SP, Hisada Y, Rennie A, Bode WD, Vora R, Subramaniam S, Cooley B, Andrade-Gordon P, Antoniak S, Mackman N. The factor Xa inhibitor rivaroxaban reduces cardiac dysfunction in a mouse model of myocardial infarction. Thromb Res. 2018 07; 167:128-134. PMID: 29843086
     
  10. Subramaniam S, Scharrer I. Procoagulant activity during viral infections. Front Biosci (Landmark Ed). 2018 Jan 01; 23:1060-1081. PMID: 28930589; DOI: 10.2741/4633;
     
Showing 10 of 22 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 22 publications over 7 distinct years, with a maximum of 6 publications in 2017

YearPublications
20112
20142
20162
20176
20184
20194
20212

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