Saravanan Subramaniam, PhD
Research Assistant Professor
Boston University Chobanian & Avedisian School of Medicine
Pulmonary Center

PhD, Justus Liebig Universitaet Giessen
BPharm, Tamil Nadu Dr. M.G.R. Medical University

Pronouns: he/him/his

Dr. Saravanan Subramaniam completed his bachelor and master degree in pharmacy and pharmacology from India and doctoral degree from Germany. He had completed his postdoctoral research at the center for thrombosis and hemostasis, Johannes Gutenberg University (Germany) and at McAllister Heart Institute, University of North Carolina (USA). He has published his research work in several high impact factor journals (Blood, circulation research, Hepatology, etc.,) and received several awards and travel grants. His area of specialization includes Intravital imaging of blood cells and coagulation.

Anti-complement therapy: a drug target for COVID-19-induced inflammation and coagulation
03/01/2021 - 02/28/2022 (PI)
Aniara Diagnostica


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Subramaniam S, Liu J, Fletcher C, Ramchandran R, Weiler H. Coagulation Factor IIIa (f3a) Knockdown in Zebrafish Leads to Defective Angiogenesis and Mild Bleeding Phenotype. Front Cell Dev Biol. 2022; 10:852989. PMID: 35386206; DOI: 10.3389/fcell.2022.852989;
  2. Carossino M, Kenney D, O'Connell AK, Montanaro P, Tseng AE, Gertje HP, Grosz KA, Ericsson M, Huber BR, Kurnick SA, Subramaniam S, Kirkland TA, Walker JR, Francis KP, Klose AD, Paragas N, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal Neurodissemination and SARS-CoV-2 Tropism in K18-hACE2 Mice Is Only Partially Dependent on hACE2 Expression. Viruses. 2022 03 05; 14(3).View Related Profiles. PMID: 35336942; DOI: 10.3390/v14030535;
  3. Eaton N, Subramaniam S, Schulte ML, Drew C, Jakab D, Haberichter SL, Weiler H, Falet H. Bleeding diathesis in mice lacking JAK2 in platelets. Blood Adv. 2021 08 10; 5(15):2969-2981. PMID: 34342643; DOI: 10.1182/bloodadvances.2020003032;
  4. Subramaniam S, Ogoti Y, Hernandez I, Zogg M, Botros F, Burns R, DeRousse JT, Dockendorff C, Mackman N, Antoniak S, Fletcher C, Weiler H. A thrombin-PAR1/2 feedback loop amplifies thromboinflammatory endothelial responses to the viral RNA analogue poly(I:C). Blood Adv. 2021 07 13; 5(13):2760-2774. PMID: 34242391; DOI: 10.1182/bloodadvances.2021004360;
  5. Subramaniam S, Ruf W, Bosmann M. Advocacy of targeting protease-activated receptors in severe coronavirus disease 2019. Br J Pharmacol. 2022 May; 179(10):2086-2099.View Related Profiles. PMID: 34235728; DOI: 10.1111/bph.15587;
  6. Carossino M, Montanaro P, O'Connell A, Kenney D, Gertje H, Grosz KA, Kurnick SA, Bosmann M, Saeed M, Balasuriya UBR, Douam F, Crossland NA. Fatal neuroinvasion of SARS-CoV-2 in K18-hACE2 mice is partially dependent on hACE2 expression. bioRxiv. 2021 Jan 15.View Related Profiles. PMID: 33469581; DOI: 10.1101/2021.01.13.425144;
  7. Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice. mBio. 2019 10 22; 10(5). PMID: 31641089; DOI: 10.1128/mBio.02298-19;
  8. Subramaniam S, Boukhlouf S, Fletcher C. A bacterial metabolite, trimethylamine N-oxide, disrupts the hemostasis balance in human primary endothelial cells but no coagulopathy in mice. Blood Coagul Fibrinolysis. 2019 Oct; 30(7):324-330. PMID: 31490208; DOI: 10.1097/MBC.0000000000000838;
  9. Gao C, Schroeder JA, Xue F, Jing W, Cai Y, Scheck A, Subramaniam S, Rao S, Weiler H, Czechowicz A, Shi Q. Nongenotoxic antibody-drug conjugate conditioning enables safe and effective platelet gene therapy of hemophilia A mice. Blood Adv. 2019 09 24; 3(18):2700-2711. PMID: 31515232; DOI: 10.1182/bloodadvances.2019000516;
  10. Gandhi DM, Rosas R, Greve E, Kentala K, D-R Diby N, Snyder VA, Stephans A, Yeung THW, Subramaniam S, DiMilo E, Kurtenbach KE, Arnold LA, Weiler H, Dockendorff C. The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability. Bioorg Med Chem. 2019 09 01; 27(17):3788-3796. PMID: 31320211; DOI: 10.1016/j.bmc.2019.06.043;
Showing 10 of 26 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 26 publications over 8 distinct years, with a maximum of 6 publications in 2017


2019 Early career award: International Society on Thrombosis and Haemostasis (ISTH 2019) AUSTRALIA
2018 Young Investigator Award: CSATVB-2018, Toronto, CANADA

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72 East Concord Street
Boston MA 02118
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