Cataldo "Aldo" Leone is Dean and the Spencer N. Frankl Professor in Dental Medicine at Boston University Henry M. Goldman School of Dental Medicine (GSDM) as well as a board-certified periodontist.
Over an academic career spanning more than three decades, Dr. Leone has garnered enormous respect as an administrator, teacher, researcher, and faculty colleague. Dually appointed as Professor of Periodontology and Professor of Molecular & Cell Biology at GSDM, Dr. Leone served as the dental school’s Associate Dean for Academic Affairs prior to his appointment in 2021 as the school's fourth Dean. He also holds a hospital appointment at Boston Medical Center. Prior to joining GSDM in 1999, he was on the faculty at the University of Florida and Tufts University.
Earlier in his career, Dr. Leone was engaged in structure-function investigations of proteoglycans and salivary proteins, as well as immuno-inflammatory mechanisms in periodontal disease. More recent studies have focused on educational outcomes. Dean Leone has published over 100 original articles, abstracts and book chapters and has served as a reviewer for the Journal of Periodontology, Journal of Dental Education, Journal of Dental Research, and New England Journal of Medicine.
Upon his appointment as Associate Dean for Academic Affairs in 2008, Dr. Leone established himself as a nationally recognized educator and leader in dental education and administration through his work as a dental Curriculum Consultant/Site Visitor for the American Dental Association's (ADA) Commission on Dental Accreditation (CODA), which accredits dental schools. Most recently, he was elected as Commissioner for the ADA's Commission on Dental Accreditation for the term 2022-2026. He also previously served as Chair, ADA Joint Commission on National Dental Examinations (JCNDE), which launched both the Integrated National Board Dental Examination (INBDE) and the Dental Licensing Objective Structured Clinical Licensing Examination (DLOSCE) under his tenure.
For more than 15 years, Dr. Leone has participated on BU's University and Faculty Councils, and is a recent past chair of the latter body.
Nationally, Dean Leone holds membership to Omicron Kappa Upsilon (OKU) Dental Honor Society and is a fellow of the International College of Dentists and the American College of Dentists. He is also active in numerous professional organizations.
For his contributions to student and resident education, Dean Leone was recognized with the dental school's distinguished Spencer N. Frankl Award for Excellence in Teaching in 2012. He has also been recognized with The American Academy of Periodontology's Educator Award for Outstanding Teaching and Mentoring in Periodontics.
Dean Leone holds a Doctor of Dental Medicine degree from the University of Pittsburgh, a graduate certificate in Periodontology and a Doctor of Medical Sciences degree in Oral Biology from Harvard University (in conjunction with the Department of Biology at M.I.T.).
Diversity, Equity, Inclusion and Accessibility
As the son of immigrants and a first-generation college student, I have long understood the life-changing nature of equitable and inclusive access to education and career opportunities. I continually endeavor to “pay it forward” in my work as an academic dentist by promoting diversity, equity, inclusion, and access.
I served as program director of a NIH/NIDCR T35 grant titled “Short-term Research Training for Women and Minority Dental Students,” which provided stipends and housing for summer research projects of students from five dental schools. Several of these trainees went on to faculty positions, including one at BU. I have been actively involved in our post-baccalaureate pipeline program: the Oral Health Sciences (OHS) program in the BUMC General Medical Sciences (GMS) division of the medical school. The program has been successful in increasing the diversity of our student body. I developed the school’s Patient Seminar Series, in which individuals suffering from rare dental, oral, and craniofacial diseases discuss their journey in overcoming personal adversity in dealing with the healthcare, insurance, and legal systems. These guest patients help “put a face” on oral-related conditions encountered only rarely, but which have marked consequences for those affected.
The dental school, like the university, has a long-standing commitment to community engagement. For example, we provide access to education and treatment in Boston public schools and health centers, as well as providing care to the local community. As with other health professions, dentistry has acknowledged the critical importance of social determinants of health in achieving successful and sustainable health outcomes, especially for historically underserved populations. In this regard, our curriculum broadens students’ education beyond acquiring technical skills, which are necessary but not sufficient in graduating culturally, as well as technically, competent health care providers.
As the school’s dean, I have been promoting DEIA efforts on a broader and more systemic scale, to ensure an environment that is both supportive and welcoming to all. I am building the capacity needed to achieve successful outcomes that are sustained while ensuring that this work does not fall on one or very few individuals with insufficient resources. Recruitment of BIPOC faculty is a current priority to help our increasingly diverse student body feel truly part of the school community; that is, being taught by faculty who look like them and have a set of shared experiences. Our Rainbow Alliance, originally formed by and for LGBTQIA+ staff, now includes faculty as well; for students, SQuAD (Society for Queers and Allies in Dentistry) has just been organized. In addition, as a follow up to our pre-pandemic climate survey, the school will be launching a series of interactive sessions to help staff to be their authentic selves in the workplace.
Thus, the school remains committed to DEIA in realizing fully our teaching, research, and service missions. We know what we need to do, we remain excited about the tasks at hand, and we look forward to an enriched academic culture that embraces all.
Spencer N. Frankl Professor in Dental Medicine
Boston University Henry M. Goldman School of Dental Medicine
Professor
Boston University Henry M. Goldman School of Dental Medicine
Periodontology
Professor
Boston University Henry M. Goldman School of Dental Medicine
Molecular & Cell Biology
Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences
Publications listed below are automatically derived from MEDLINE/PubMed and other
sources, which might result in incorrect or missing publications. Faculty can
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Alshihayb TS, Kaye EA, Zhao Y, Leone CW, Heaton B. A quantitative bias analysis to assess the impact of unmeasured confounding on associations between diabetes and periodontitis. J Clin Periodontol. 2021 01; 48(1):51-60.View Related Profiles. PMID: 33031608
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Alshihayb TS, Kaye EA, Zhao Y, Leone CW, Heaton B. The impact of periodontitis exposure misclassification bias from partial-mouth measurements on association with diabetes and cardiovascular disease. J Clin Periodontol. 2020 12; 47(12):1457-1465.View Related Profiles. PMID: 32990981
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Davies TA, Kaye E, Stahlberger M, Abbas M, Sarkis C, Reed L, Dunham L, Schreiber BM, Leone C, Mascarenhas AK. Improving Diversity of Dental Students Through the Boston University Master's of Oral Health Sciences Postbaccalaureate Program. J Dent Educ. 2019 Mar; 83(3):287-295.View Related Profiles. PMID: 30692183
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Hoskin ER, Johnsen DC, Saksena Y, Horvath Z, de Peralta T, Fleisher N, Marshall TA, Leone C. Dental Educators' Perceptions of Educational Learning Domains. J Dent Educ. 2019 Jan; 83(1):79-87.View Related Profiles. PMID: 30600253
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Alsulaiman AA, Kaye E, Jones J, Cabral H, Leone C, Will L, Garcia R. Incisor malalignment and the risk of periodontal disease progression. Am J Orthod Dentofacial Orthop. 2018 Apr; 153(4):512-522.View Related Profiles. PMID: 29602343
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Brugnami F, Caiazzo A, Leone C . Review of intraoral harvesting for bone augmentation: Selection criteria, alternative sites, and case report. Compendium of Continuing Education in Dentistry. 2010; 31(7).
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Brugnami F, Caiazzo A, Leone C. Local intraoral autologous bone harvesting for dental implant treatment: alternative sources and criteria of choice. Keio J Med. 2009 Mar; 58(1):24-8. PMID: 19398881
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Kayal RA, Tsatsas D, Bauer MA, Allen B, Al-Sebaei MO, Kakar S, Leone CW, Morgan EF, Gerstenfeld LC, Einhorn TA, Graves DT. Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity. J Bone Miner Res. 2007 Apr; 22(4):560-8.View Related Profiles. PMID: 17243865; PMCID: PMC3109431; DOI: 10.1359/jbmr.070115;
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Graves DT, Naguib G, Lu H, Leone C, Hsue H, Krall E. Inflammation is more persistent in type 1 diabetic mice. J Dent Res. 2005 Apr; 84(4):324-8.View Related Profiles. PMID: 15790737
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Santana RB, Uzel MI, Gusman H, Gunaydin Y, Jones JA, Leone CW. Morphometric analysis of the furcation anatomy of mandibular molars. J Periodontol. 2004 Jun; 75(6):824-9.View Related Profiles. PMID: 15295948
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Gusman H, Leone C, Helmerhorst EJ, Nunn M, Flora B, Troxler RF, Oppenheim FG. Human salivary gland-specific daily variations in histatin concentrations determined by a novel quantitation technique. Arch Oral Biol. 2004 Jan; 49(1):11-22.View Related Profiles. PMID: 14693192
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Li J, Helmerhorst EJ, Leone CW, Troxler RF, Yaskell T, Haffajee AD, Socransky SS, Oppenheim FG. Identification of early microbial colonizers in human dental biofilm. J Appl Microbiol. 2004; 97(6):1311-8.View Related Profiles. PMID: 15546422
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He H, Liu R, Desta T, Leone C, Gerstenfeld LC, Graves DT. Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss. Endocrinology. 2004 Jan; 145(1):447-52.View Related Profiles. PMID: 14525917
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Leone CW. The predictors of periodontal disease progression following treatment need more research. Evidence-Based Dentistry. 2003; 4:59.
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Leone CW. Presence or absence of periodontal pathogens does not distinguish between chronic and aggressive periodontitis. Evidence-Based Dentistry. 2003; 4:60.
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Leone CW, Oppenheim FG. Physical and chemical aspects of saliva as indicators of risk for dental caries in humans. J Dent Educ. 2001 Oct; 65(10):1054-62.View Related Profiles. PMID: 11699977
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Maurer S, Leone CW. Use of a serially layered, double connective tissue graft approach to enhance maxillary anterior esthetics. Int J Periodontics Restorative Dent. 2001 Oct; 21(5):497-503. PMID: 11693242
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Maurer S, Hayes C, Leone C. Width of keratinized tissue after gingivoplasty of healed subepithelial connective tissue grafts. J Periodontol. 2000 Nov; 71(11):1729-36.View Related Profiles. PMID: 11128921
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Zervou C, Kugel G, Leone C, Zavras A, Doherty EH, White GE. Enameloplasty effects on microleakage of pit and fissure sealants under load: an in vitro study. J Clin Pediatr Dent. 2000; 24(4):279-85.View Related Profiles. PMID: 11314412
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Brugnami F, Then PR, Moroi H, Kabani S, Leone CW. GBR in human extraction sockets and ridge defects prior to implant placement: clinical results and histologic evidence of osteoblastic and osteoclastic activities in DFDBA. Int J Periodontics Restorative Dent. 1999 Jun; 19(3):259-67. PMID: 10635172
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Carro OM, Evans SA, Leone CW. Effect of inflammation on the proliferation of human gingival epithelial cells in vitro. J Periodontol. 1997 Nov; 68(11):1070-5. PMID: 9407399
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Hempton T, Leone C. A review of root resective therapy as a treatment option for maxillary molars. J Am Dent Assoc. 1997 Apr; 128(4):449-55. PMID: 9103795
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Lai YL, Leone CW. The relation between smoking and periodontal disease. J Mass Dent Soc. 1997; 46(3):17-8, 20-2, 24. PMID: 9540712
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Hempton TJ, Leone C. The effects of smoking on periodontal disease and periodontal therapies. J Mass Dent Soc. 1997; 46(1):33-5, 38-40. PMID: 9540728
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Brugnami F, Then PR, Moroi H, Leone CW. Histologic evaluation of human extraction sockets treated with demineralized freeze-dried bone allograft (DFDBA) and cell occlusive membrane. J Periodontol. 1996 Aug; 67(8):821-5. PMID: 8866322
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Cohen ES, Leone CW. The reconstruction of a smile. Alpha Omegan. 1995; 88(4):20-4. PMID: 9470538
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Leone CW. Periodontology in the 21st century: from scientific art to artistic science. Alpha Omegan. 1995; 88(4):13-5. PMID: 9470536
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Leone CW, Monaco G. Gingival Fibroblasts: Inhibition by Heparin. Dental Cadmos. 1993; 61:66-73.
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Kojima T, Leone CW, Marchildon GA, Marcum JA, Rosenberg RD. Isolation and characterization of heparan sulfate proteoglycans produced by cloned rat microvascular endothelial cells. J Biol Chem. 1992 Mar 05; 267(7):4859-69. PMID: 1537864
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Leone CW, Clark WB, McArthur WP. Host responses in the etiology and pathogenesis of periodontal disease. Curr Opin Dent. 1991 Feb; 1(1):29-36. PMID: 1912630
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Svanberg GK, Leone CW. Periodontal Disease Activity. Today's FDA/Florida Dental Journal. 1991; 3(12):1.
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De Agostini AL, Lau HK, Leone C, Youssoufian H, Rosenberg RD. Cell mutants defective in synthesizing a heparan sulfate proteoglycan with regions of defined monosaccharide sequence. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):9784-8. PMID: 2263629; PMCID: PMC55258
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Leone CW, Hassell TM. The Surgical Component of Comprehensive Periodontal Therapy. Today's FDA/Florida Dental Journal. 1990; 2(3):1-5.
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Leone CW. Anesthetic management of lithium-treated patients. Anesth Prog. 1984 May-Jun; 31(3):138-40. PMID: 6591847; PMCID: PMC2235801
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Williams RC, Leone CW, Jeffcoat MK, Nitzan D, Goldhaber P. Tetracycline treatment of periodontal disease in the beagle dog. II. The cultivable periodontal pocket flora. J Periodontal Res. 1981 Nov; 16(6):666-74. PMID: 6460865
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Williams RC, Leone CW, Jeffcoat MK, Scott ER, Goldhaber P. Tetracycline treatment of periodontal disease in the beagle dog. I. Clinical and radiographic course over 12 months-maximal effect on rate of alveolar bone loss. J Periodontal Res. 1981 Nov; 16(6):659-65. PMID: 6460864
This graph shows the total number of publications by year, by first, middle/unknown,
or last author.
Year | Publications |
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1981 | 2 |
1984 | 1 |
1990 | 2 |
1991 | 2 |
1992 | 1 |
1993 | 1 |
1995 | 2 |
1996 | 1 |
1997 | 4 |
1999 | 1 |
2000 | 2 |
2001 | 2 |
2003 | 3 |
2004 | 3 |
2005 | 1 |
2006 | 1 |
2007 | 1 |
2009 | 1 |
2010 | 1 |
2013 | 1 |
2018 | 1 |
2019 | 2 |
2020 | 2 |