Tien Hsu, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Hematology & Medical Oncology

PhD, Medical University of South Carolina



Expertise includes: Cell biology; Cancer biology; Epithelial morphogenesis; Cell migration; Tumor suppressor gene; Drosophila genetics.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Boston Medical Center





VHL tumor suppressor gene and the initiation of renal cell carcinoma
04/01/2015 - 03/31/2018 (PI)
NIH-NCI

VHL and FGFR Signaling in Angiogenesis
01/20/2010 - 04/30/2011 (PI)
NIH-NCI



Yr Title Project-Sub Proj Pubs
2015 VHL tumor suppressor gene and the initiation of renal cell carcinoma 5R01CA109860-11 27
2014 VHL tumor suppressor gene and the initiation of renal cell carcinoma 5R01CA109860-10 27
2013 VHL tumor suppressor gene and the initiation of renal cell carcinoma 5R01CA109860-09 27
2013 VHL tumor suppressor gene and the initiation of renal cell carcinoma 3R01CA109860-09S1 27
2012 VHL tumor suppressor gene and the initiation of renal cell carcinoma 5R01CA109860-08 27
2012 VHL tumor suppressor gene and the initiation of renal cell carcinoma 3R01CA109860-08S1 27
2011 VHL tumor suppressor gene and the initiation of renal cell carcinoma 2R01CA109860-07 27
2009 Ets1 and FGFR FUNCTIONS IN EPITHELIAL CELL MIGRATION 5P01CA078582-10-5 83
2008 VHL and FGFR signaling in angiogenesis 5R01CA109860-05 27
2008 Ets1 and FGFR FUNCTIONS IN EPITHELIAL CELL MIGRATION 5P01CA078582-09-5 83
Showing 10 of 33 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Romani P, Ignesti M, Gargiulo G, Hsu T, Cavaliere V. Extracellular NME proteins: a player or a bystander? Lab Invest. 2017 Oct 16. PMID: 29035383.
  2. Kuo CY, Lin CH, Hsu T. VHL Inactivation in Precancerous Kidney Cells Induces an Inflammatory Response via ER Stress-Activated IRE1a Signaling. Cancer Res. 2017 Jul 01; 77(13):3406-3416. PMID: 28533271.
  3. Bader HL, Hsu T. Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model. BMC Cancer. 2016 Oct 12; 16(1):797. PMID: 27733136.
  4. Romani P, Papi A, Ignesti M, Soccolini G, Hsu T, Gargiulo G, Spisni E, Cavaliere V. Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein. Naunyn Schmiedebergs Arch Pharmacol. 2016 Nov; 389(11):1171-1182. PMID: 27449069.
  5. Hsu T, Steeg PS, Zollo M, Wieland T. Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified. Naunyn Schmiedebergs Arch Pharmacol. 2015 Feb; 388(2):109-17. PMID: 25585611; DOI: 10.1007/s00210-014-1079-9;.
  6. Lin CH, Dammai V, Adryan B, Hsu T. Interaction between Nm23 and the tumor suppressor VHL. Naunyn Schmiedebergs Arch Pharmacol. 2015 Feb; 388(2):143-52. PMID: 24915993; DOI: 10.1007/s00210-014-1002-4;.
  7. Ignesti M, Barraco M, Nallamothu G, Woolworth JA, Duchi S, Gargiulo G, Cavaliere V, Hsu T. Notch signaling during development requires the function of awd, the Drosophila homolog of human metastasis suppressor gene Nm23. BMC Biol. 2014; 12:12.View Related Profiles. PMID: 24528630; PMCID: PMC3937027; DOI: 10.1186/1741-7007-12-12;.
  8. Bader HL, Hsu T. Systemic VHL gene functions and the VHL disease. FEBS Lett. 2012 Jun 4; 586(11):1562-9.View Related Profiles. PMID: 22673568; PMCID: PMC3372859; DOI: 10.1016/j.febslet.2012.04.032;.
  9. Hsu T. Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms. Oncogene. 2012 May 3; 31(18):2247-57. PMID: 21996733; PMCID: PMC3343179; DOI: 10.1038/onc.2011.442;.
  10. Liby TA, Spyropoulos P, Buff Lindner H, Eldridge J, Beeson C, Hsu T, Muise-Helmericks RC. Akt3 controls vascular endothelial growth factor secretion and angiogenesis in ovarian cancer cells. Int J Cancer. 2012 Feb 1; 130(3):532-43. PMID: 21351097; PMCID: PMC3189303; DOI: 10.1002/ijc.26010;.
Showing 10 of 32 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 32 publications over 15 distinct years, with a maximum of 5 publications in 2008

YearPublications
20021
20033
20042
20054
20061
20071
20085
20092
20102
20113
20121
20142
20151
20162
20172
Contact for Mentoring:


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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