STTR Phase I: Novel HDAC Inhibitors for Treatment of Hemoglobinopathies09/01/2017 - 08/31/2019 (Multi-PI)
PI:
Susan P. Perrine-Faller, MDCetya Therapeutics NIH NHLBI1R41HL136068-01
Launching a Novel Therapeutic of Global Hemoglobin Diseases01/01/2016 - 12/31/2017 (PI)
Harrington Discovery Institute
Novel Globin Gene Modulators12/01/2015 - 11/30/2017 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases4R01DK052962-13
Novel Globin Gene Modulators12/07/2012 - 11/30/2015 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases5R01DK052962-12
Topical Therapeutic to Promote Healing of Chronic Wounds08/01/2013 - 07/31/2015 (Subcontract PI)
Phoenicia Biosciences, Inc. NIH NIGMS1R41GM101869-01A1
Next Generation Therapeutics for Hemoglobinopathies07/01/2012 - 06/30/2014 (Subcontract PI)
Phoenicia Biosciences, Inc. NIH NHLBI1R41HL108516-01
Selective HDAC Inhibitors for Treatment of Hemoglobinopathies08/01/2013 - 04/30/2014 (Subcontract PI)
Acetylon Pharmaceuticals, Inc. NIH NHLBI1R41HL118917-01
Novel Globin Modulators/ Comparative Activity of Compounds09/12/2008 - 09/11/2009 (PI)
Hemaquest Pharmaceuticals, Inc.
Novel Globin Gene Modulators06/01/1998 - 05/31/2009 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases5 R01 DK52962 09
Erythropoiesis & Pulse Arginine Butyrate in Sickle Cell Disease09/30/2002 - 09/29/2008 (PI)
HHS/Food and Drug Administration
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Mechanisms for Stat 3-Mediated y-globin Gene Silencing04/11/2003 - 03/31/2007 (PI)
University of Texas NIH NHLBI
Oral Therapeutics for Viral Malignancies09/30/2002 - 08/31/2005 (Co-PI)
PI:
Douglas V. Faller, MD, PhDGene Regulation Laboratories NIH NCI
Oral Agents to Induce Fetal Hemoglobin09/01/2002 - 08/31/2005 (Co-PI)
PI:
Douglas V. Faller, MD, PhDGene Regulation Laboratories NIH NHLBI
Fetal Globin Induction in Beta Thalassemia09/30/1998 - 07/31/2004 (PI)
NIH/National Heart, Lung, and Blood Institute5 R01 HL61208 05
Arginine Butyrate and Ganciclovir in Epstein Barr Virus (+) Malignancy09/30/1998 - 09/29/2003 (PI)
HHS/Food and Drug Administration
Molecular Mechanisms of Cell Proliferation Induced by Short Chain Fatty Acid Derivatives07/15/2001 - 07/15/2003 (Dept Sponsor)
Aplastic Anemia & MDS International Foundation Inc
Fetal Globin Induction in Beta Thalassemia07/01/2001 - 06/30/2003 (Dept Sponsor)
Cooley's Anemia Foundation
A Phase II Trial of Butyrate for Refractory Sickle Cell Ulcers09/30/1997 - 09/29/2001 (Co-PI)
PI:
Douglas V. Faller, MD, PhDFDA - Office of Orphan Products
Sickle Cell - Butyrate Study04/01/2003 - 03/31/2008 (PI)
NIH-NHLBI5 U54 HL070819-05