Douglas V. Faller, MD, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Hematology & Medical Oncology

MD, Harvard University
PhD, Massachusetts Institute of Technology




Dr. Douglas Faller is a Boston-based physician/scientist with over 15 years of pharmaceutical and biotech experience involving discovery, pre-clinical and clinical development of small molecules for several therapeutic areas, specializing in oncology and hematology, plus over 25 years of academic clinical and laboratory research experience in the fields of drug discovery and development, oncology and hematology, cell and molecular biology, management of professionals, including the programmatic organization of large groups of scientists, and development of research and drug development programs.

Active Staff Privileges
Boston Medical Center
Medicine
Hematology & Medical Oncology



Boston University Cross-Disciplinary Training in Nanotechnology for Cancer
09/01/2010 - 07/31/2016 (Co-PI)
NIH/National Cancer Institute
5R25CA153955-05

Targeting N-RAS as a Therapeutic Approach for Melanoma
05/01/2012 - 04/30/2016 (PI)
Melanoma Research Alliance


PKC-Inhibitors as Targeted Therapeutics for Systemic Sclerosis
01/15/2014 - 01/14/2016 (PI)
Scleroderma Foundation


Non-Oncogene Addiction as a Targeted Therapy for Pancreatic Cancer
01/01/2013 - 12/31/2015 (PI)
NIH/National Cancer Institute
5R21CA164245-02

Institutional Research Grant
01/01/2012 - 12/31/2015 (PI of Sub-Project / SP)
PI: Avrum Spira, MD
American Cancer Society - MA Division


Mechanisms of Action and Signaling by Steroid Hormone Antagonists
06/01/2003 - 12/31/2015 (PI)
NIH/National Cancer Institute
5R01CA101992-09

Targeting N-Ras as a Terapeutic Approach to Melanoma
09/30/2012 - 09/29/2014 (PI)
Department of Defense/Army Medical Research Acquisition Activity


Synthetic Lethality as a Targeted Approach to Advanced Prostate Cancer
03/01/2011 - 02/28/2014 (PI)
Department of Defense/Army


Virus-Targeted Therapy for Malignancies
09/26/2011 - 08/31/2012 (PI)
Phoenicia Biosciences, Inc. NIH NCI
R43CA153474-01A1

Virus-Targeted Therapeutic for Epstein-Barr Virus-Associated Lymphomas
08/01/2009 - 07/31/2012 (PI)
V Foundation


Showing 10 of 40 results. Show All Results

SWOG - NCI
02/23/2004 - 02/28/2018 (PI)
South West Oncology Group



Yr Title Project-Sub Proj Pubs
2014 Non-Oncogene Addiction as a Targeted Therapy for Pancreatic Cancer 5R21CA164245-02 5
2014 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 5R25CA153955-05 41
2014 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-05S1 41
2014 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-05S2 41
2013 Non-Oncogene Addiction as a Targeted Therapy for Pancreatic Cancer 1R21CA164245-01A1 5
2013 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 5R25CA153955-04 41
2013 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-04S1 41
2013 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-04S2 41
2013 Mechanisms of Action and Signaling by Steroid Hormone Antagonists 5R01CA101992-09 20
2012 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 5R25CA153955-03 41
Showing 10 of 89 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Faessel H, Nemunaitis J, Bauer TM, Lockhart AC, Faller DV, Sedarati F, Zhou X, Venkatakrishnan K, Harvey RD. Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours. Br J Clin Pharmacol. 2019 Mar 07. PMID: 30845347.
     
  2. Bell JA, Galaznik A, Farrelly E, Blazer M, Murty S, Ogbonnaya A, Eaddy M, Fram RJ, Faller DV, Kota VK. A retrospective study evaluating treatment patterns and survival outcomes in elderly patients with acute myeloid leukemia treated in the United States with either 7+3 or a hypomethylating agent. Leuk Res. 2019 Mar; 78:45-51. PMID: 30716655.
     
  3. Faller DV. Response to "Selective PKCd Inhibitor B106 Elicits Uveal Melanoma Growth Inhibitory Effects Independent of Activated PKC Isoforms". ACS Chem Biol. 2019 Jan 18; 14(1):131. PMID: 30525445.
     
  4. Bell JA, Galaznik A, Blazer M, Shih HC, Farrelly E, Ogbonnaya A, Eaddy M, Fram RJ, Faller DV. Economic Burden of Patients Treated for Higher-Risk Myelodysplastic Syndromes (HR-MDS) in Routine Clinical Care in the United States. Pharmacoecon Open. 2018 Oct 15. PMID: 30324565.
     
  5. Moos WH, Faller DV, Glavas IP, Harpp DN, Irwin MH, Kanara I, Pinkert CA, Powers WR, Steliou K, Vavvas DG, Kodukula K. A New Approach to Treating Neurodegenerative Otologic Disorders. Biores Open Access. 2018; 7(1):107-115. PMID: 30069423.
     
  6. Bell JA, Galaznik A, Blazer M, Farrelly E, Ogbonnaya A, Raju A, Eaddy M, Fram RJ, Faller DV. Transfusion-free interval is associated with improved survival in patients with higher-risk myelodysplastic syndromes engaged in routine care. Leuk Lymphoma. 2019 Jan; 60(1):49-59. PMID: 29932781.
     
  7. Bell JA, Galaznik A, Farrelly E, Blazer M, Murty S, Ogbonnaya A, Eaddy M, Fram RJ, Faller DV, Kota V. Economic burden of elderly patients with acute myeloid leukemia treated in routine clinical care in the United States. Leuk Res. 2018 08; 71:27-33. PMID: 29944984.
     
  8. Lockhart AC, Bauer TM, Aggarwal C, Lee CB, Harvey RD, Cohen RB, Sedarati F, Nip TK, Faessel H, Dash AB, Dezube BJ, Faller DV, Dowlati A. Phase Ib study of pevonedistat, a NEDD8-activating enzyme inhibitor, in combination with docetaxel, carboplatin and paclitaxel, or gemcitabine, in patients with advanced solid tumors. Invest New Drugs. 2019 Feb; 37(1):87-97. PMID: 29781056.
     
  9. Bell JA, Galaznik A, Huelin R, Stokes M, Guo Y, Fram RJ, Faller DV. Effectiveness and Safety of Therapeutic Regimens for Elderly Patients With Acute Myeloid Leukemia: A Systematic Literature Review. Clin Lymphoma Myeloma Leuk. 2018 07; 18(7):e303-e314. PMID: 29802009.
     
  10. Bell JA, Galaznik A, Huelin R, Stokes M, Guo Y, Fram RJ, Faller DV. Systematic Literature Review of Treatment Options and Clinical Outcomes for Patients With Higher-Risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia. Clin Lymphoma Myeloma Leuk. 2018 04; 18(4):e157-e166. PMID: 29475821.
     
Showing 10 of 285 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 263 publications over 37 distinct years, with a maximum of 16 publications in 1988 and 1995

YearPublications
19831
19842
19855
19867
198715
198816
19896
19909
19919
19923
19935
199410
199516
199613
199710
19987
19999
20007
20017
20029
20034
20042
20055
200612
20076
20089
20099
20104
20117
20125
20134
20146
20154
20165
20173
201810
20192
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Boston MA 02118
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