MD, Harvard University
PhD, Massachusetts Institute of Technology
BS, Massachusetts Institute of Technology

Testing of new HDAC Inhibitors in EBV lymphoma
01/01/2011 - 01/01/2012 (PI)
Hemaquest Pharmaceuticals, Inc.

Targeting the Telomere as a Therapeutic Approach to Prostate Cancer
03/01/2006 - 02/28/2009 (PI)
Department of Defense/Army

Cooperative Research Agreement Between Boston University and HemaQuest Pharmaceutical to Develop Hematological and Cancer Therapeutics
01/01/2008 - 12/31/2008 (PI)
Hemaquest Pharmaceuticals, Inc.

PKC-Delta as a Therapeutic Target in Colon Cancer
07/01/2006 - 06/30/2008 (PI)
American Association for Cancer Research

Novel Globin Gene Modulators
06/01/2003 - 05/31/2008 (Co-PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5 R01 DK52962 07

Pharmacophore-Modeled Screening for HbF-Inducing Agents
09/13/2004 - 08/31/2006 (PI)
Gene Regulation Laboratories NIH NHLBI

Development of a Ras-Targeted Therapeutic Approach to Lung Cancer
09/01/2004 - 08/31/2006 (PI)
Philip Morris Inc

Institutional Research Grant
07/01/2000 - 06/30/2006 (PI)
American Cancer Society, National

Development of a Ras-Targeted Cancer Therapeutic
06/01/2004 - 05/31/2006 (PI)
Gene Regulation Laboratories NIH NCI

Sensitization of Prostate Tumors to Retinoids by Short-Chain Fatty Acids
06/01/2000 - 03/31/2006 (PI)
Department of Defense/Army

Showing 10 of 30 results. Show All Results

02/23/2004 - 02/28/2018 (PI)
South West Oncology Group


Yr Title Project-Sub Proj Pubs
2022 Development of a Clinical Hemoglobin Modulator 5R33HL147845-03
2021 Development of a Clinical Hemoglobin Modulator 5R33HL147845-02
2020 Development of a Clinical Hemoglobin Modulator 1R33HL147845-01A1
2014 Non-Oncogene Addiction as a Targeted Therapy for Pancreatic Cancer 5R21CA164245-02 5
2014 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-05S2 44
2014 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-05S1 44
2014 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 5R25CA153955-05 44
2013 Non-Oncogene Addiction as a Targeted Therapy for Pancreatic Cancer 1R21CA164245-01A1 5
2013 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-04S2 44
2013 Boston University Cross-Disciplinary Training in Nanotechnology for Cancer 3R25CA153955-04S1 44
Showing 10 of 92 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Zhou X, Sedarati F, Faller DV, Zhao D, Faessel HM, Chowdhury S, Bolleddula J, Li Y, Venkatakrishnan K, Papai Z. Phase I study assessing the mass balance, pharmacokinetics, and excretion of [14C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors. Invest New Drugs. 2021 04; 39(2):488-498. PMID: 33089874
  2. Voss MH, Gordon MS, Mita M, Rini B, Makker V, Macarulla T, Smith DC, Cervantes A, Puzanov I, Pili R, Wang D, Jalal S, Pant S, Patel MR, Neuwirth RL, Enke A, Shou Y, Sedarati F, Faller DV, Burris HA. Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer. Br J Cancer. 2020 11; 123(11):1590-1598. PMID: 32913286
  3. Pearson ADJ, Zwaan CM, Kolb EA, Karres D, Guillot J, Kim SY, Marshall L, Tasian SK, Smith M, Cooper T, Adamson PC, Barry E, Benettaib B, Binlich F, Borgman A, Brivio E, Capdeville R, Delgado D, Faller D, Fogelstrand L, Fraenkel PG, Hasle H, Heenen D, Kaspers G, Kieran M, Klusmann JH, Lesa G, Ligas F, Mappa S, Mohamed H, Moore A, Morris J, Nottage K, Reinhardt D, Scobie N, Simko S, Winkler T, Norga K, Reaman G, Vassal G. Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration. Eur J Cancer. 2020 09; 136:116-129. PMID: 32688206
  4. Moos WH, Faller DV, Glavas IP, Harpp DN, Kanara I, Mavrakis AN, Pernokas J, Pernokas M, Pinkert CA, Powers WR, Sampani K, Steliou K, Vavvas DG, Zamboni RJ, Kodukula K, Chen X. Klotho Pathways, Myelination Disorders, Neurodegenerative Diseases, and Epigenetic Drugs. Biores Open Access. 2020; 9(1):94-105. PMID: 32257625
  5. Faessel HM, Mould DR, Zhou X, Faller DV, Sedarati F, Venkatakrishnan K. Population pharmacokinetics of pevonedistat alone or in combination with standard of care in patients with solid tumours or haematological malignancies. Br J Clin Pharmacol. 2019 11; 85(11):2568-2579. PMID: 31355467
  6. Bell JA, Galaznik A, Pompilus F, Strzok S, Bejar R, Scipione F, Fram RJ, Faller DV, Cano S, Marquis P. A pragmatic patient-reported outcome strategy for rare disease clinical trials: application of the EORTC item library to myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia. J Patient Rep Outcomes. 2019 Jun 19; 3(1):35. PMID: 31218454
  7. Bell JA, Galaznik A, Blazer M, Shih HC, Farrelly E, Ogbonnaya A, Eaddy M, Fram RJ, Faller DV. Economic Burden of Patients Treated for Higher-Risk Myelodysplastic Syndromes (HR-MDS) in Routine Clinical Care in the United States. Pharmacoecon Open. 2019 Jun; 3(2):237-245. PMID: 30324565
  8. Faessel H, Nemunaitis J, Bauer TM, Lockhart AC, Faller DV, Sedarati F, Zhou X, Venkatakrishnan K, Harvey RD. Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours. Br J Clin Pharmacol. 2019 07; 85(7):1464-1473. PMID: 30845347
  9. Bell JA, Galaznik A, Farrelly E, Blazer M, Murty S, Ogbonnaya A, Eaddy M, Fram RJ, Faller DV, Kota VK. A retrospective study evaluating treatment patterns and survival outcomes in elderly patients with acute myeloid leukemia treated in the United States with either 7+3 or a hypomethylating agent. Leuk Res. 2019 03; 78:45-51. PMID: 30716655
  10. Faller DV. Response to "Selective PKCd Inhibitor B106 Elicits Uveal Melanoma Growth Inhibitory Effects Independent of Activated PKC Isoforms". ACS Chem Biol. 2019 01 18; 14(1):131. PMID: 30525445
Showing 10 of 291 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 34 publications over 16 distinct years, with a maximum of 5 publications in 1987


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