Susan P. Perrine-Faller, MD
Boston University School of Medicine
Dept of Pediatrics
Pediatric Subspecialties (Pediatric Hematology)

MD, Tufts University School of Medicine
MMS, Rutgers University–Camden
SM, Harvard School of Public Health

Boston University School of Medicine
Hematology & Medical Oncology

Boston University School of Medicine
Pharmacology & Experimental Therapeutics

Active Staff Privileges
Boston Medical Center
Hematology & Medical Oncology

Launching a Novel Therapeutic of Global Hemoglobin Diseases
01/01/2016 - 12/31/2017 (PI)
Harrington Discovery Institute

Novel Globin Gene Modulators
12/01/2015 - 11/30/2017 (PI)
NIH/National Diabetes & Digestive & Kidn

Novel Globin Gene Modulators
12/07/2012 - 11/30/2015 (PI)
NIH/National Diabetes & Digestive & Kidn

Topical Therapeutic to Promote Healing of Chronic Wounds
08/01/2013 - 07/31/2015 (PI)
Phoenicia Biosciences, Inc. NIH NIGMS

Next Generation Therapeutics for Hemoglobinopathies
07/01/2012 - 06/30/2014 (PI)
Phoenicia Biosciences, Inc. NIH NHLBI

Selective HDAC Inhibitors for Treatment of Hemoglobinopathies
08/01/2013 - 04/30/2014 (PI)
Acetylon Pharmaceuticals, Inc. NIH NHLBI

Novel Globin Modulators/ Comparative Activity of Compounds
09/12/2008 - 09/11/2009 (PI)
Hemaquest Pharmaceuticals, Inc.

Novel Globin Gene Modulators
06/01/1998 - 05/31/2009 (PI)
NIH/National Diabetes & Digestive & Kidney Diseases
5 R01 DK52962 09

Erythropoiesis & Pulse Arginine Butyrate in Sickle Cell Disease
09/30/2002 - 09/29/2008 (PI)
HHS/Food and Drug Administration

Mechanisms for Stat 3-Mediated y-globin Gene Silencing
04/11/2003 - 03/31/2007 (PI)
University of Texas NIH NHLBI

Showing 10 of 17 results. Show All Results

Sickle Cell - Butyrate Study
04/01/2003 - 03/31/2008 (PI)

Yr Title Project-Sub Proj Pubs
2017 Novel HDAC Inhibitors for Treatment of Hemoglobinopathies 1R41HL136068-01
2016 Virus-targeted therapeutic for EBV-Associated Malignancies 2R44CA153474-02A1
2016 Novel Globin Gene Modulators 4R01DK052962-13 20
2015 Development of a clinical hemoglobin modulator 5R42HL110727-03 1
2015 Novel Globin Gene Modulators 5R01DK052962-12 20
2014 Development of a clinical hemoglobin modulator 2R42HL110727-02 1
2014 Novel Globin Gene Modulators 5R01DK052962-11 20
2013 Topical Therapeutic to Promote Healing of Chronic Wounds 1R41GM101869-01A1
2013 Novel Globin Gene Modulators 2R01DK052962-10A1 20
2012 Next Generation Therapeutics for Hemoglobinopathies 1R41HL108516-01A1 5
Showing 10 of 57 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Perrine SP, Pace BS, Faller DV. Targeted fetal hemoglobin induction for treatment of beta hemoglobinopathies. Hematol Oncol Clin North Am. 2014 Apr; 28(2):233-48.View Related Profiles. PMID: 24589264; DOI: 10.1016/j.hoc.2013.11.009;.
  2. Perrine SP, Wargin WA, Boosalis MS, Wallis WJ, Case S, Keefer JR, Faller DV, Welch WC, Berenson RJ. Evaluation of safety and pharmacokinetics of sodium 2,2 dimethylbutyrate, a novel short chain fatty acid derivative, in a phase 1, double-blind, placebo-controlled, single-dose, and repeat-dose studies in healthy volunteers. J Clin Pharmacol. 2011 Aug; 51(8):1186-94.View Related Profiles. PMID: 21422239; DOI: 10.1177/0091270010379810;.
  3. McMahon L, Tamary H, Askin M, Adams-Graves P, Eberhardt RT, Sutton M, Wright EC, Castaneda SA, Faller DV, Perrine SP. A randomized phase II trial of Arginine Butyrate with standard local therapy in refractory sickle cell leg ulcers. Br J Haematol. 2010 Dec; 151(5):516-24.View Related Profiles. PMID: 20955402; DOI: 10.1111/j.1365-2141.2010.08395.x;.
  4. Perrine SP, Castaneda SA, Chui DH, Faller DV, Berenson RJ, Siritanaratku N, Fucharoen S. Fetal globin gene inducers: novel agents and new potential. Ann N Y Acad Sci. 2010 Aug; 1202:158-64.View Related Profiles. PMID: 20712788; DOI: 10.1111/j.1749-6632.2010.05593.x;.
  5. Taher AT, Musallam KM, Nasreddine W, Perrine SP, El-Hajj TI, Beydoun A. Effects of divalproex sodium on hemoglobin level. Blood Cells Mol Dis. 2009 Jul-Aug; 43(1):49-52. PMID: 19254854; DOI: 10.1016/j.bcmd.2009.01.015;.
  6. Perrine SP. Fetal globin stimulant therapies in the beta-hemoglobinopathies: principles and current potential. Pediatr Ann. 2008 May; 37(5):339-46. PMID: 18543545.
  7. Perrine SP. Fetal globin induction--can it cure beta thalassemia? Hematology Am Soc Hematol Educ Program. 2005; 38-44. PMID: 16304357.
  8. Perrine SP, Castaneda SA, Boosalis MS, White GL, Jones BM, Bohacek R. Induction of fetal globin in beta-thalassemia: Cellular obstacles and molecular progress. Ann N Y Acad Sci. 2005; 1054:257-65.View Related Profiles. PMID: 16339673.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 8 publications over 6 distinct years, with a maximum of 2 publications in 2005 and 2010

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72 E. Concord St Instructional (L)
Boston MA 02118
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