David Hing-Kwei Chui, MD
Professor
Boston University School of Medicine
Dept of Medicine
Hematology & Medical Oncology

MD, McGill University



Expertise includes: Globin gene mutations; Hemoglobin diseases; Thalassmeias; and Regulation of fetal hemoglobin expression.

Professor
Boston University School of Medicine
Pathology & Laboratory Medicine


Active Staff Hospital Privileges
Boston Medical Center
Pathology & Laboratory Medicine



2011 McGill University Alumni Association: D. Lorne Gales Award
2007-2016 The Best Doctors in America
2002 The Thalassemia Foundation of Canada: Hour Glass Award
2000-2002 The Thalassemia Foundation of Canada: Chair, Medical Advisory Board
1991 Association of American Physicians: elected to membership
1987-1991 NIH: Hematology Study Section
1980-1984 BLOOD: Editorial Board member
1980 American Society for Clinical Investigation: elected to membership
1971-1976 Medical Research Council of Canada: Scholar
1970 Royal College of Physicians of Canada: Fellow


GLOBIN GENE EXPRESSION IN SICKLE CELL GENOTYPE-SPECIFIC IPS CELLS
07/05/2011 - 06/30/2017 (Co-PI)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
5U01HL107443-05

GLOBIN GENE EXPRESSION IN SICKLE CELL GENOTYPE-SPECIFIC IPS CELLS
07/05/2011 - 06/30/2016 (Co-PI)
PI: Martin H. Steinberg, MD
NIH/National Heart, Lung, and Blood Institute
1U01HL107443-01


Sickle Cell - Research Scholar
04/01/2003 - 03/31/2008 (PI)
NIH-NHLBI
5 U54 HL070819-05 (A)



Yr Title Project-Sub Proj Pubs
2014 Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells 5U01HL107443-04 6
2013 Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells 5U01HL107443-03 6
2012 Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells 5U01HL107443-02 6
2011 Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells 1U01HL107443-01 6
2009 Genetic Modulation of HbF in Beta Thalassemia 5R01DK069646-05 16
2008 AUTOMATED ID OF PROTEINS, VARIANTS &POST-TRANSLATIONAL MODIFICATIONS 5P41RR010888-12-5180 236
2008 Genetic Modulation of HbF in Beta Thalassemia 5R01DK069646-04 16
2007 AUTOMATED ID OF PROTEINS, VARIANTS &POST-TRANSLATIONAL MODIFICATIONS 2P41RR010888-11-8001 236
2007 Genetic Modulation of HbF in Beta Thalassemia 5R01DK069646-03 16
2006 AUTOMATED ID OF PROTEINS, VARIANTS &POST-TRANSLATIONAL MODIFICATIONS 5P41RR010888-10-7080 236
Showing 10 of 14 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Singh SA, Sarangi S, Appiah-Kubi A, Hsu P, Smith WB, Gallagher PG, Glader B, Chui DHK. Hb Adana (HBA2 or HBA1: c.179G > A) and alpha thalassemia: Genotype-phenotype correlation. Pediatr Blood Cancer. 2018 Sep; 65(9):e27220. PMID: 29749692.
     
  2. Akinbami AO, Sobota AE, Luo HY, Chui DHK, Steinberg MH. A Mild Phenotype of Severe ß+ Thalassemia in a 16-Month-Old Boy. J Pediatr Hematol Oncol. 2018 Apr; 40(3):e145-e147.View Related Profiles. PMID: 29309373.
     
  3. Leung A, Zulick E, Skvir N, Vanuytsel K, Morrison TA, Naing ZH, Wang Z, Dai Y, Chui DHK, Steinberg MH, Sherr DH, Murphy GJ. Notch and Aryl Hydrocarbon Receptor Signaling Impact Definitive Hematopoiesis from Human Pluripotent Stem Cells. Stem Cells. 2018 Jul; 36(7):1004-1019.View Related Profiles. PMID: 29569827.
     
  4. Morrison TA, Wilcox I, Luo HY, Farrell JJ, Kurita R, Nakamura Y, Murphy GJ, Cui S, Steinberg MH, Chui DHK. A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. Blood Cells Mol Dis. 2018 Mar; 69:1-9.View Related Profiles. PMID: 29227829.
     
  5. Shaikho EM, Farrell JJ, Alsultan A, Qutub H, Al-Ali AK, Figueiredo MS, Chui DHK, Farrer LA, Murphy GJ, Mostoslavsky G, Sebastiani P, Steinberg MH. A phased SNP-based classification of sickle cell anemia HBB haplotypes. BMC Genomics. 2017 Aug 11; 18(1):608.View Related Profiles. PMID: 28800727.
     
  6. Cancio MI, Aygun B, Chui DHK, Rothman JA, Scott JP, Estepp JH, Hankins JS. The clinical severity of hemoglobin S/Black (A ?dß)0 -thalassemia. Pediatr Blood Cancer. 2017 Nov; 64(11). PMID: 28453928; DOI: 10.1002/pbc.26596;.
     
  7. Pernudy-Ubau A, Salinas-Molina J, Requenez Y, Ortiz-Lopez M, Puller AC, García-Rosales K, Rodríguez-Estrada A, Rodríguez-Romero W, Mejía-Baltodano G, Luo HY, Chui DHK. Hb Presbyterian (HBB: c.327C>G) in a Nicaraguan Family. Hemoglobin. 2017 Jan; 41(1):50-52. PMID: 28395541.
     
  8. Jiang Z, Luo HY, Farrell JJ, Zhang Z, Schulz VP, Albarawi D, Steinberg MH, Al-Allawi NAS, Gallagher PG, Forget BG, Chui DHK. A variant Sp1 (R218Q) transcription factor might enhance HbF expression in ß0 -thalassaemia homozygotes. Br J Haematol. 2018 Mar; 180(5):755-757.View Related Profiles. PMID: 28240767; DOI: 10.1111/bjh.14445;.
     
  9. Park S, Gianotti-Sommer A, Molina-Estevez FJ, Vanuytsel K, Skvir N, Leung A, Rozelle SS, Shaikho EM, Weir I, Jiang Z, Luo HY, Chui DHK, Figueiredo MS, Alsultan A, Al-Ali A, Sebastiani P, Steinberg MH, Mostoslavsky G, Murphy GJ. A Comprehensive, Ethnically Diverse Library of Sickle Cell Disease-Specific Induced Pluripotent Stem Cells. Stem Cell Reports. 2017 Apr 11; 8(4):1076-1085.View Related Profiles. PMID: 28111279; DOI: 10.1016/j.stemcr.2016.12.017;.
     
  10. Vathipadiekal V, Farrell JJ, Wang S, Edward HL, Shappell H, Al-Rubaish AM, Al-Muhanna F, Naserullah Z, Alsuliman A, Qutub HO, Simkin I, Farrer LA, Jiang Z, Luo HY, Huang S, Mostoslavsky G, Murphy GJ, Patra PK, Chui DH, Alsultan A, Al-Ali AK, Sebastiani P, Steinberg MH. A candidate transacting modulator of fetal hemoglobin gene expression in the Arab-Indian haplotype of sickle cell anemia. Am J Hematol. 2016 Nov; 91(11):1118-1122.View Related Profiles. PMID: 27501013; DOI: 10.1002/ajh.24527;.
     
Showing 10 of 100 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 95 publications over 31 distinct years, with a maximum of 9 publications in 2011

YearPublications
19801
19822
19841
19863
19882
19892
19901
19922
19933
19952
19972
19983
20001
20018
20023
20032
20042
20056
20063
20072
20085
20094
20103
20119
20123
20135
20142
20151
20163
20176
20183
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Genetics
Contact for Mentoring:


75 E. Newton St Evans Building
Boston MA 02118
Google Map


Chui's Networks
Click the "See All" links for more information and interactive visualizations
Concepts
_
Co-Authors
_
Similar People
_
Same Department