Keywords
Last Name

Hirohide Asai

TitlePostdoctoral Fellow
InstitutionBoston University School of Medicine
Address85 E. Concord St
Boston MA 02118
Phone(617) 638-4300
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nat Commun. 2016; 7:10332. PMID: 26755131.
    View in: PubMed
  2. Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kügler S, Ikezu T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nat Neurosci. 2015 Nov; 18(11):1584-93. PMID: 26436904.
    View in: PubMed
  3. Woodbury ME, Freilich RW, Cheng CJ, Asai H, Ikezu S, Boucher JD, Slack F, Ikezu T. miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction. J Neurosci. 2015 Jul 1; 35(26):9764-81. PMID: 26134658.
    View in: PubMed
  4. Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Ann Neurol. 2014 Sep; 76(3):379-92. PMID: 25043464.
    View in: PubMed
  5. Asai H, Ikezu S, Woodbury ME, Yonemoto GM, Cui L, Ikezu T. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1. Am J Pathol. 2014 Mar; 184(3):808-18. PMID: 24418258.
    View in: PubMed
  6. Asai H, Hirano M, Kiriyama T, Ikeda M, Ueno S. Naturally- and experimentally-designed restorations of the Parkin gene deficit in autosomal recessive juvenile parkinsonism. Biochem Biophys Res Commun. 2010 Jan 1; 391(1):800-5. PMID: 19945426.
    View in: PubMed
  7. Asai H, Hirano M, Shimada K, Kiriyama T, Furiya Y, Ikeda M, Iwamoto T, Mori T, Nishinaka K, Konishi N, Udaka F, Ueno S. Protein kinase C gamma, a protein causative for dominant ataxia, negatively regulates nuclear import of recessive-ataxia-related aprataxin. Hum Mol Genet. 2009 Oct 1; 18(19):3533-43. PMID: 19561170.
    View in: PubMed
  8. Asai H, Hirano M, Furiya Y, Udaka F, Morikawa M, Kanbayashi T, Shimizu T, Ueno S. Cerebrospinal fluid-orexin levels and sleep attacks in four patients with Parkinson's disease. Clin Neurol Neurosurg. 2009 May; 111(4):341-4. PMID: 19097685.
    View in: PubMed
  9. Tonomura Y, Hirano M, Shimada K, Asai H, Ikeda M, Kataoka H, Tanaka I, Konishi N, Ueno S. Treatable fluctuating mental impairment in a patient with Bardet-Biedl syndrome. Clin Neurol Neurosurg. 2009 Jan; 111(1):102-4. PMID: 18938027.
    View in: PubMed
  10. Kiriyama T, Hirano M, Asai H, Ikeda M, Furiya Y, Ueno S. Restoration of nuclear-import failure caused by triple A syndrome and oxidative stress. Biochem Biophys Res Commun. 2008 Oct 3; 374(4):631-4. PMID: 18662670.
    View in: PubMed
  11. Asai H, Udaka F, Hirano M, Ueno S. Odor abnormalities caused by bilateral thalamic infarction. Clin Neurol Neurosurg. 2008 May; 110(5):500-1. PMID: 18329165.
    View in: PubMed
  12. Furiya Y, Hirano M, Nomura M, Asai H, Kiriyama T, Ueno S. Peripheral neuropathy in chromosome16q22.1 linked autosomal dominant cerebellar ataxia. J Neurol Neurosurg Psychiatry. 2007 Sep; 78(9):1009-11. PMID: 17702787.
    View in: PubMed
  13. Kiriyama T, Tanizawa E, Hirano M, Shinkai T, Asai H, Furiya Y, Ueno S. SPECT revealed cortical dysfunction in a patient who had genetically definite megalencephalic leukoencephalopathy with subcortical cysts. Clin Neurol Neurosurg. 2007 Jul; 109(6):526-30. PMID: 17507156.
    View in: PubMed
  14. Hirano M, Asai H, Kiriyama T, Furiya Y, Iwamoto T, Nishiwaki T, Yamamoto A, Mori T, Ueno S. Short half-lives of ataxia-associated aprataxin proteins in neuronal cells. Neurosci Lett. 2007 May 29; 419(2):184-7. PMID: 17485165.
    View in: PubMed
  15. Asai H, Hirano M, Udaka F, Shimada K, Oda M, Kubori T, Nishinaka K, Tsujimura T, Izumi Y, Konishi N, Matsumoto S, Kameyama M, Ueno S. Sympathetic disturbances increase risk of sudden cardiac arrest in sporadic ALS. J Neurol Sci. 2007 Mar 15; 254(1-2):78-83. PMID: 17303172.
    View in: PubMed
  16. Hirano M, Yamamoto A, Mori T, Lan L, Iwamoto TA, Aoki M, Shimada K, Furiya Y, Kariya S, Asai H, Yasui A, Nishiwaki T, Imoto K, Kobayashi N, Kiriyama T, Nagata T, Konishi N, Itoyama Y, Ueno S. DNA single-strand break repair is impaired in aprataxin-related ataxia. Ann Neurol. 2007 Feb; 61(2):162-74. PMID: 17315206.
    View in: PubMed
  17. Hirano M, Furiya Y, Asai H, Yasui A, Ueno S. ALADINI482S causes selective failure of nuclear protein import and hypersensitivity to oxidative stress in triple A syndrome. Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7):2298-303. PMID: 16467144.
    View in: PubMed
  18. Asai H, Udaka F, Hirano M, Minami T, Oda M, Kubori T, Nishinaka K, Kameyama M, Ueno S. Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson's disease. Parkinsonism Relat Disord. 2005 Dec; 11(8):499-502. PMID: 16263322.
    View in: PubMed
  19. Kariya S, Hirano M, Uesato S, Nagai Y, Nagaoka Y, Furiya Y, Asai H, Fujikake N, Toda T, Ueno S. Cytoprotective effect of novel histone deacetylase inhibitors against polyglutamine toxicity. Neurosci Lett. 2006 Jan 16; 392(3):213-5. PMID: 16199124.
    View in: PubMed
  20. Asai H, Udaka F, Oishi N, Kubori T, Kameyama M. [A case of familial essential myoclonus and epilepsy with suspected focus in the hemisphere ipsilateral to myoclonus limbs]. No To Shinkei. 2004 Jun; 56(6):509-13. PMID: 15328840.
    View in: PubMed
  21. Hirano M, Kusunoki S, Asai H, Tonomura Y, Morita D, Ueno S. A family with Campylobacter enteritis: anti-GD1a antibody with/without Guillain-Barré syndrome. Neurology. 2003 May 27; 60(10):1719-20. PMID: 12771281.
    View in: PubMed
  22. Morimoto M, Kanno H, Asai H, Tsujimura T, Fujii H, Moriyama Y, Kasugai T, Hirono A, Ohba Y, Miwa S, Kitamura Y. Pyruvate kinase deficiency of mice associated with nonspherocytic hemolytic anemia and cure of the anemia by marrow transplantation without host irradiation. Blood. 1995 Dec 1; 86(11):4323-30. PMID: 7492793.
    View in: PubMed
  23. Kanno H, Morimoto M, Fujii H, Tsujimura T, Asai H, Noguchi T, Kitamura Y, Miwa S. Primary structure of murine red blood cell-type pyruvate kinase (PK) and molecular characterization of PK deficiency identified in the CBA strain. Blood. 1995 Oct 15; 86(8):3205-10. PMID: 7579416.
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  24. Kubo T, Matsunaga T, Asai H, Kawamoto K, Kusakari J, Nomura Y, Oda M, Yanagita N, Niwa H, Uemura T, et al. Efficacy of defibrinogenation and steroid therapies on sudden deafness. Arch Otolaryngol Head Neck Surg. 1988 Jun; 114(6):649-52. PMID: 3284549.
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  25. Kagawa H, Nagai Y, Asai H. An analysis of the hyper-sharp phenomenon of myosin diffusion in an F-actin/ATP solution by computer simulation. Biophys Chem. 1988 Apr; 29(3):327-39. PMID: 3390528.
    View in: PubMed
  26. Kanakura Y, Sonoda S, Nakano T, Fujita J, Kuriu A, Asai H, Kitamura Y. Formation of mast-cell colonies in methylcellulose by mouse skin cells and development of mucosal-like mast cells from the cloned cells in the gastric mucosa of W/Wv mice. Am J Pathol. 1987 Oct; 129(1):168-76. PMID: 3661676.
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  27. Inao S, Furuse M, Hotta T, Asai H, Yoshida K, Saso K, Kaneoke Y, Motegi Y. [Hemodilutional therapy in raised intracranial pressure; observations in a case of cerebral infarction associated with polycythemia vera]. No To Shinkei. 1986 Mar; 38(3):219-24. PMID: 3707772.
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  28. Hagiwara S, Konno T, Sugiyama S, Asai H, Sugiyama E, Nakamoto H, Izumi Y, Watanabe H, Noguchi T, Ishikawa I. [Epidemiological survey on dental prophylaxis and treatment by questionnaire. Primary report]. Kokubyo Gakkai Zasshi. 1985 Dec; 52(4):643-57. PMID: 3868671.
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  29. Yokoyama M, Tomoi M, Taguchi T, Nakano T, Asai H, Ono T, Kitamura Y. Fatal antral ulcer in conventionally fed W/Wv mutant mice given indomethacin by injection. Am J Pathol. 1985 Jun; 119(3):367-75. PMID: 3860014.
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  30. Ishikawa I, Honma S, Hagiwara S, Asai H, Osada Y, Izumi Y, Watanabe H, Izumizawa K, Noguchi T. [Epidemiological survey on periodontal disease in the employees of two banks with CPITN (Community Periodontal Index of Treatment Needs)--the primary report]. Nihon Shishubyo Gakkai Kaishi. 1984 Dec; 26(4):767-78. PMID: 6600130.
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  31. Nagai Y, Asai H, Tsuchiya T. Polydispersity effects on head-to-tail polymerization of F-actin. A theoretical treatment. Biophys Chem. 1984 Nov; 20(4):319-31. PMID: 6509152.
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  32. Nagai Y, Asai H, Tsuchiya T. The average number of distinct sites visited by a one-dimensional random walker and its application to isotope exchange in polypeptides. Biophys Chem. 1981 Jun; 13(3):213-22. PMID: 17000168.
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  33. Asai H, Takagi H, Tsunoda S. Some characteristics of erythrocyte membrane and its ATPase from lamprey, Entosphenus japonicus. Comp Biochem Physiol B. 1976; 55(1):69-75. PMID: 7430.
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