Keywords
Last Name

David Henderson, MD

TitleProfessor
InstitutionBoston University School of Medicine
DepartmentPsychiatry
DivisionGeneral Psychiatry
Address720 Harrison Avenue, Suite 914
Boston MA 02118
PhoneTel: (617) 638-8141
Other Positions
TitleChair
InstitutionBoston University School of Medicine
DepartmentPsychiatry

TitleAssistant Dean
InstitutionBoston University School of Medicine
DepartmentDiversity & Multicultural Affairs

 Awards and Honors

Start-EndDescription
2014National Alliance on Mental Illness: Exemplary Psychiatrist Award
2013MGH Department of Psychiatry: Excellence in Research Mentoring
2012MGH/McLean Adult Psychiatry Residency Training Program: Psychopharmacology Supervisor Award
2012Partners Healthcare, Inc.: Partners in Excellence Award
2011Partners Healthcare, Inc.: Partners in Excellence Award
2010MGH/McLean Adult Psychiatry Residency Training Program: Psychopharmacology Supervisor Award
2008Black Enterprise: America’s Leading Doctors
2008Brockton High School Alumni Association: Distinguished Alumnus Award
2007Massachusetts General Hospital/McLean Adult Psychiatry Residency Training Program: Psychopharmacology Supervisor Award
2007American Psychiatric Association: Distinguished Fellow
2007American Psychiatric Association: Dr. Solomon Carter Fuller Award
2005Commonwealth of Massachusetts Executive Office of Health and Human Services: Department of Mental Health Distinguished Service Award for Research
2004Massachusetts Psychiatric Society: Outstanding Psychiatry Award for Clinical Psychiatry
1998Massachusetts General Hospital, Psychiatry Residency Training Program: Outstanding Teacher Award
1996Massachusetts General Hospital, Psychiatry Residency Training Program: Honorable Mention, Teacher of the Year Award
1995Massachusetts General Hospital, Psychiatry Residency Training Program: Bulfinch Award for Excellence in Teaching
1994YMCA: Black Achievers Award of Greater Boston
1992National Medical Association (Psychiatry and Behavioral Health Section): Ernest Y. Williams, M.D. Clinical Scholars of Distinction Award
1984Tufts University: McCune Smith Natural Science Award
1984Tufts University: Student Affairs Community Award for Outstanding Contribution to Community Life
 Research Expertise & Professional Interests
Dr. David Henderson is a leader in the fields of schizophrenia, medical co-morbidity, and global psychiatry. He directs the Chester Pierce Division of Global Psychiatry and the MGH Schizophrenia Clinical and Research Program (SCRP) and is principal investigator and director of the MGH Global Mental Health Clinical Research Fellowship.

His research interests include treatment-resistant schizophrenia, the use of psychopharmacological and antipsychotic agents in the treatment of schizophrenia, and the impact of antipsychotic agents on weight, cardiovascular disease, and lipid and glucose metabolism. Dr. Henderson noticed a high rate of diabetes mellitus (DM) in his clozapine-treated patients. As a result, he developed procedures for screening and early detection of diabetes in this population. Dr. Henderson focused on metabolic effects of atypical antipsychotic agents, the role of serotonin receptors, and augmentation strategies to reduce or reverse metabolic disturbances.

As Director of the SCRP, Dr. Henderson directs a leading center for the study and treatment of schizophrenia worldwide. SCRP combines clinical care, training, and clinical and neuroimaging research, with programs designed to improve long-term health and quality of life of seriously mentally ill patients though a multidisciplinary, collaborative approach with community agencies. ]SCRP has more than 20 studies and clinical trials and has trained numerous clinical researchers, fellows and residents who have pursued successful careers in academic medicine. SCRP consults in diabetes and weight management (Dr. Henderson’s current research area), psychosocial therapy, first-episode psychosis, smoking cessation and other psychosis-related issues.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Denckla CA, Ndetei DM, Mutiso VN, Musyimi CW, Musau AM, Nandoya ES, Anderson KK, Milanovic S, Henderson D, McKenzie K. Psychometric properties of the Ndetei-Othieno-Kathuku (NOK) Scale: A mental health assessment tool for an African setting. J Child Adolesc Ment Health. 2017 Apr 12; 1-11. PMID: 28401773.
    View in: PubMed
  2. Roffman JL, Petruzzi LJ, Tanner AS, Brown HE, Eryilmaz H, Ho NF, Giegold M, Silverstein NJ, Bottiglieri T, Manoach DS, Smoller JW, Henderson DC, Goff DC. Biochemical, physiological and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial. Mol Psychiatry. 2017 Mar 14. PMID: 28289280.
    View in: PubMed
  3. Musyimi CW, Mutiso V, Ndetei DM, Henderson DC, Bunders J. Mental Health Outcomes of Psychosocial Intervention Among Traditional Health Practitioner Depressed Patients in Kenya. Cult Med Psychiatry. 2017 Mar 01. PMID: 28251478.
    View in: PubMed
  4. Levey EJ, Gelaye B, Bain P, Rondon MB, Borba CP, Henderson DC, Williams MA. A systematic review of randomized controlled trials of interventions designed to decrease child abuse in high-risk families. Child Abuse Negl. 2017 Mar; 65:48-57. PMID: 28110205.
    View in: PubMed
  5. Levey EJ, Oppenheim CE, Lange BC, Plasky NS, Harris BL, Lekpeh GG, Kekulah I, Henderson DC, Borba CP. A qualitative analysis of parental loss and family separation among youth in post-conflict Liberia. Vulnerable Child Youth Stud. 2017 Jan 02; 12(1):1-16. PMID: 28163770.
    View in: PubMed
  6. Levey EJ, Oppenheim CE, Lange BC, Plasky NS, Harris BL, Lekpeh GG, Kekulah I, Henderson DC, Borba CP. A qualitative analysis of factors impacting resilience among youth in post-conflict Liberia. Child Adolesc Psychiatry Ment Health. 2016; 10:26. PMID: 27525038.
    View in: PubMed
  7. Ng LC, Petruzzi LJ, Greene MC, Mueser KT, Borba CP, Henderson DC. Posttraumatic Stress Disorder Symptoms and Social and Occupational Functioning of People With Schizophrenia. J Nerv Ment Dis. 2016 Aug; 204(8):590-8. PMID: 27105458.
    View in: PubMed
  8. Vincenzi B, Greene CM, Ulloa M, Parnarouskis L, Jackson JW, Henderson DC. Lithium or Valproate Adjunctive Therapy to Second-generation Antipsychotics and Metabolic Variables in Patients With Schizophrenia or Schizoaffective Disorder. J Psychiatr Pract. 2016 May; 22(3):175-82. PMID: 27123797.
    View in: PubMed
  9. Nasser AF, Henderson DC, Fava M, Fudala PJ, Twumasi-Ankrah P, Kouassi A, Heidbreder C. Efficacy, Safety, and Tolerability of RBP-7000 Once-Monthly Risperidone for the Treatment of Acute Schizophrenia: An 8-Week, Randomized, Double-Blind, Placebo-Controlled, Multicenter Phase 3 Study. J Clin Psychopharmacol. 2016 Apr; 36(2):130-40. PMID: 26862829.
    View in: PubMed
  10. Ng LC, Magidson JF, Hock RS, Joska JA, Fekadu A, Hanlon C, Galler JR, Safren SA, Borba CP, Fricchione GL, Henderson DC. Proposed Training Areas for Global Mental Health Researchers. Acad Psychiatry. 2016 Aug; 40(4):679-85. PMID: 26976395.
    View in: PubMed
  11. Pullen SJ, Petruzzi L, Lange BC, Parnarouskis L, Dominguez S, Harris B, Quiterio N, Durham MP, Lekpeh G, Manobah B, Slopadoe SP, Diandy VC, Payne AJ, Henderson DC, Borba CP. A Qualitative Analysis of Substance Use among Liberian Youth: Understanding Behaviors, Consequences, and Protective Factors Involving School Youth and the School Milieu. Int J Ment Health Psychiatry. 2016 Feb; 2(1). PMID: 27158680.
    View in: PubMed
  12. Chouinard VA, Pingali SM, Chouinard G, Henderson DC, Mallya SG, Cypess AM, Cohen BM, Öngür D. Factors associated with overweight and obesity in schizophrenia, schizoaffective and bipolar disorders. Psychiatry Res. 2016 Mar 30; 237:304-10. PMID: 26805561.
    View in: PubMed
  13. Zhong QY, Gelaye B, Miller M, Fricchione GL, Cai T, Johnson PA, Henderson DC, Williams MA. Suicidal behavior-related hospitalizations among pregnant women in the USA, 2006-2012. Arch Womens Ment Health. 2016 Jun; 19(3):463-72. PMID: 26680447.
    View in: PubMed
  14. Borba CP, Ng LC, Stevenson A, Vesga-Lopez O, Harris BL, Parnarouskis L, Gray DA, Carney JR, Domínguez S, Wang EK, Boxill R, Song SJ, Henderson DC. A mental health needs assessment of children and adolescents in post-conflict Liberia: results from a quantitative key-informant survey. Int J Cult Ment Health. 2016 Jan 02; 9(1):56-70. PMID: 26807147.
    View in: PubMed
  15. Koh KA, Bharel M, Henderson DC. Nutrition for homeless populations: shelters and soup kitchens as opportunities for intervention. Public Health Nutr. 2016 May; 19(7):1312-4. PMID: 26434381.
    View in: PubMed
  16. Ng LC, Hanlon C, Yimer G, Henderson DC, Fekadu A. Ethics in global health research: the need for balance. Lancet Glob Health. 2015 Sep; 3(9):e516-7. PMID: 26275322.
    View in: PubMed
  17. Gelaye B, Kajeepeta S, Zhong QY, Borba CP, Rondon MB, Sánchez SE, Henderson DC, Williams MA. Childhood abuse is associated with stress-related sleep disturbance and poor sleep quality in pregnancy. Sleep Med. 2015 Oct; 16(10):1274-80. PMID: 26429757.
    View in: PubMed
  18. Magidson JF, Stevenson A, Ng LC, Hock RS, Borba CP, Namey LB, Carney J, Joska JA, Kagee A, Fekadu A, Bangsberg DR, Safren SA, Fricchione GL, Henderson DC. Massachusetts General Hospital Global Psychiatric Clinical Research Training Program: A New Fellowship in Global Mental Health. Acad Psychiatry. 2016 Aug; 40(4):695-7. PMID: 26108399.
    View in: PubMed
  19. Gelaye B, Barrios YV, Zhong QY, Rondon MB, Borba CP, Sánchez SE, Henderson DC, Williams MA. Association of poor subjective sleep quality with suicidal ideation among pregnant Peruvian women. Gen Hosp Psychiatry. 2015 Sep-Oct; 37(5):441-7. PMID: 25983188.
    View in: PubMed
  20. Henderson DC, Vincenzi B, Andrea NV, Ulloa M, Copeland PM. Pathophysiological mechanisms of increased cardiometabolic risk in people with schizophrenia and other severe mental illnesses. Lancet Psychiatry. 2015 May; 2(5):452-64. PMID: 26360288.
    View in: PubMed
  21. Borba CP, Gelaye B, Zayas L, Ulloa M, Lavelle J, Mollica RF, Henderson DC. Making strides towards better mental health care in Peru: Results from a primary care mental health training. Int J Clin Psychiatry Ment Health. 2015 Apr; 3(1):9-19. PMID: 27054141.
    View in: PubMed
  22. MacLaurin SA, Henderson DC, Freudenreich O. Delineating responsibility: primary care provider perspective. Psychiatr Serv. 2015 Mar 1; 66(3):333. PMID: 25727131.
    View in: PubMed
  23. Welch LC, Litman HJ, Borba CP, Vincenzi B, Henderson DC. Does a Physician's Attitude toward a Patient with Mental Illness Affect Clinical Management of Diabetes? Results from a Mixed-Method Study. Health Serv Res. 2015 Aug; 50(4):998-1020. PMID: 25487069.
    View in: PubMed
  24. Zhong QY, Gelaye B, Rondon MB, Sánchez SE, Simon GE, Henderson DC, Barrios YV, Sánchez PM, Williams MA. Using the Patient Health Questionnaire (PHQ-9) and the Edinburgh Postnatal Depression Scale (EPDS) to assess suicidal ideation among pregnant women in Lima, Peru. Arch Womens Ment Health. 2015 Dec; 18(6):783-92. PMID: 25369907.
    View in: PubMed
  25. Vincenzi B, Stock S, Borba CP, Cleary SM, Oppenheim CE, Petruzzi LJ, Fan X, Copeland PM, Freudenreich O, Cather C, Henderson DC. A randomized placebo-controlled pilot study of pravastatin as an adjunctive therapy in schizophrenia patients: effect on inflammation, psychopathology, cognition and lipid metabolism. Schizophr Res. 2014 Nov; 159(2-3):395-403. PMID: 25261882.
    View in: PubMed
  26. Amatniek J, Canuso CM, Deutsch SI, Henderson DC, Mao L, Mikesell C, Rodriguez S, Sheehan J, Alphs L. Safety of paliperidone extended-release in patients with schizophrenia or schizoaffective disorder and hepatic disease. Clin Schizophr Relat Psychoses. 2014 Apr; 8(1):8-20. PMID: 23428785.
    View in: PubMed
  27. Zhong Q, Gelaye B, Rondon M, Sánchez SE, García PJ, Sánchez E, Barrios YV, Simon GE, Henderson DC, Cripe SM, Williams MA. Comparative performance of Patient Health Questionnaire-9 and Edinburgh Postnatal Depression Scale for screening antepartum depression. J Affect Disord. 2014 Jun; 162:1-7. PMID: 24766996.
    View in: PubMed
  28. Fekadu A, Mesfin M, Medhin G, Alem A, Teferra S, Gebre-Eyesus T, Seboxa T, Assefa A, Hussein J, Lemma MT, Borba C, Henderson DC, Hanlon C, Shibre T. Adjuvant therapy with minocycline for schizophrenia (The MINOS Trial): study protocol for a double-blind randomized placebo-controlled trial. Trials. 2013; 14:406. PMID: 24279305.
    View in: PubMed
  29. Gray DA, Borba CP, Harris BL, Dominguez S, Boxill R, Wang EK, Henderson DC. Understanding cohort differences in appraisals of reconstruction priorities of mental health systems in postconflict Liberia. Afr J Psychiatry (Johannesbg). 2013 Nov 19; 16(6). PMID: 24173636.
    View in: PubMed
  30. Magill SS, Klompas M, Balk R, Burns SM, Deutschman CS, Diekema D, Fridkin S, Greene L, Guh A, Gutterman D, Hammer B, Henderson D, Hess DR, Hill NS, Horan T, Kollef M, Levy M, Septimus E, Vanantwerpen C, Wright D, Lipsett P. Developing a new, national approach to surveillance for ventilator-associated events. Am J Crit Care. 2013 Nov; 22(6):469-73. PMID: 24186816.
    View in: PubMed
  31. Irwin KE, Henderson DC, Knight HP, Pirl WF. Cancer care for individuals with schizophrenia. Cancer. 2014 Feb 1; 120(3):323-34. PMID: 24151022.
    View in: PubMed
  32. Jarskog LF, Hamer RM, Catellier DJ, Stewart DD, Lavange L, Ray N, Golden LH, Lieberman JA, Stroup TS. Metformin for weight loss and metabolic control in overweight outpatients with schizophrenia and schizoaffective disorder. Am J Psychiatry. 2013 Sep; 170(9):1032-40. PMID: 23846733.
    View in: PubMed
  33. Thakurathi N, Stock S, Oppenheim CE, Borba CP, Vincenzi B, Seidman LJ, Stone WS, Henderson DC. Open-label pilot study on vitamin D3 supplementation for antipsychotic-associated metabolic anomalies. Int Clin Psychopharmacol. 2013 Sep; 28(5):275-82. PMID: 23694999.
    View in: PubMed
  34. Levey EJ, Borba CP, Harris BL, Carney JR, Dominguez S, Wang EK, Boxill R, Henderson DC. Assessment of the needs of vulnerable youth populations in post-conflict Liberia. Afr J Psychiatry (Johannesbg). 2013 Sep; 16(5):349-55. PMID: 24051668.
    View in: PubMed
  35. Vincenzi B, Borba CP, Gray DA, Copeland PM, Wang X, Fan X, Aragam GG, Henderson DC. An exploratory study examining lipid-lowering medications in reducing fasting serum lipids in schizophrenia patients treated with atypical antipsychotics. Ann Clin Psychiatry. 2013 May; 25(2):141-8. PMID: 23638445.
    View in: PubMed
  36. Fan X, Liu E, Freudenreich O, Copeland P, Hayden D, Ghebremichael M, Cohen B, Ongur D, Goff DC, Henderson DC. No effect of adjunctive, repeated-dose intranasal insulin treatment on psychopathology and cognition in patients with schizophrenia. J Clin Psychopharmacol. 2013 Apr; 33(2):226-30. PMID: 23422397.
    View in: PubMed
  37. Li J, Li X, Liu E, Copeland P, Freudenreich O, Goff DC, Henderson DC, Song X, Fan X. No effect of adjunctive, repeated dose intranasal insulin treatment on body metabolism in patients with schizophrenia. Schizophr Res. 2013 May; 146(1-3):40-5. PMID: 23434504.
    View in: PubMed
  38. Freudenreich O, Henderson DC, Sanders KM, Goff DC. Training in a clozapine clinic for psychiatry residents: a plea and suggestions for implementation. Acad Psychiatry. 2013 Jan 1; 37(1):27-30. PMID: 23338869.
    View in: PubMed
  39. Thakurathi N, Vincenzi B, Henderson DC. Assessing the prospect of donepezil in improving cognitive impairment in patients with schizophrenia. Expert Opin Investig Drugs. 2013 Feb; 22(2):259-65. PMID: 23215841.
    View in: PubMed
  40. Fan X, Borba CP, Copeland P, Hayden D, Freudenreich O, Goff DC, Henderson DC. Metabolic effects of adjunctive aripiprazole in clozapine-treated patients with schizophrenia. Acta Psychiatr Scand. 2013 Mar; 127(3):217-26. PMID: 22943577.
    View in: PubMed
  41. Yi Z, Fan X, Wang J, Liu D, Freudenreich O, Goff D, Henderson DC. Rosiglitazone and cognitive function in clozapine-treated patients with schizophrenia: a pilot study. Psychiatry Res. 2012 Dec 30; 200(2-3):79-82. PMID: 22727707.
    View in: PubMed
  42. Wang J, Fan X, Liu D, Yi Z, Freudenreich O, Goff D, Henderson DC. Both physical activity and food intake are associated with metabolic risks in patients with schizophrenia. Schizophr Res. 2012 Sep; 140(1-3):260-1. PMID: 22682987.
    View in: PubMed
  43. Wiechers IR, Viron M, Stoklosa J, Freudenreich O, Henderson DC, Weiss A. Impact of a metabolic screening bundle on rates of screening for metabolic syndrome in a psychiatry resident outpatient clinic. Acad Psychiatry. 2012 Mar 1; 36(2):118-21. PMID: 22532201.
    View in: PubMed
  44. Fricchione GL, Borba CP, Alem A, Shibre T, Carney JR, Henderson DC. Capacity building in global mental health: professional training. Harv Rev Psychiatry. 2012 Jan-Feb; 20(1):47-57. PMID: 22335182.
    View in: PubMed
  45. Borba CP, Fan X, Copeland PM, Paiva A, Freudenreich O, Henderson DC. Placebo-controlled pilot study of ramelteon for adiposity and lipids in patients with schizophrenia. J Clin Psychopharmacol. 2011 Oct; 31(5):653-8. PMID: 21869685.
    View in: PubMed
  46. Tranulis C, Goff D, Henderson DC, Freudenreich O. Becoming adherent to antipsychotics: a qualitative study of treatment-experienced schizophrenia patients. Psychiatr Serv. 2011 Aug; 62(8):888-92. PMID: 21807827.
    View in: PubMed
  47. Henderson DC, Freudenreich O, Borba CP, Wang X, Copeland PM, Macklin E, Fan X, Cather C, Goff DC. Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia. Schizophr Res. 2011 Aug; 130(1-3):53-6. PMID: 21565464.
    View in: PubMed
  48. Fan X, Copeland PM, Liu EY, Chiang E, Freudenreich O, Goff DC, Henderson DC. No effect of single-dose intranasal insulin treatment on verbal memory and sustained attention in patients with schizophrenia. J Clin Psychopharmacol. 2011 Apr; 31(2):231-4. PMID: 21346605.
    View in: PubMed
  49. Fan X, Liu EY, Hoffman VP, Potts AJ, Sharma B, Henderson DC. Triglyceride/high-density lipoprotein cholesterol ratio: a surrogate to predict insulin resistance and low-density lipoprotein cholesterol particle size in nondiabetic patients with schizophrenia. J Clin Psychiatry. 2011 Jun; 72(6):806-12. PMID: 21208572.
    View in: PubMed
  50. Wang J, Liu EY, Freudenreich O, Goff D, Henderson DC, Fan X. Phenotypic characteristics in metabolically obese but normal weight non-diabetic patients with schizophrenia. Schizophr Res. 2010 Dec; 124(1-3):49-53. PMID: 20947306.
    View in: PubMed
  51. Nykiel S, Henderson D, Bhide G, Freudenreich O. Lithium to allow clozapine prescribing in benign ethnic neutropenia. Clin Schizophr Relat Psychoses. 2010 Jul; 4(2):138-40. PMID: 20643636.
    View in: PubMed
  52. Henderson DC. Antipsychotic treatment associated with higher risk of hyperglycaemia in older persons with diabetes. Evid Based Ment Health. 2010 May; 13(2):60. PMID: 21856623.
    View in: PubMed
  53. Fan X, Liu EY, Freudenreich O, Park JH, Liu D, Wang J, Yi Z, Goff D, Henderson DC. Higher white blood cell counts are associated with an increased risk for metabolic syndrome and more severe psychopathology in non-diabetic patients with schizophrenia. Schizophr Res. 2010 May; 118(1-3):211-7. PMID: 20189773.
    View in: PubMed
  54. Freudenreich O, Brockman MA, Henderson DC, Evins AE, Fan X, Walsh JP, Goff DC. Analysis of peripheral immune activation in schizophrenia using quantitative reverse-transcription polymerase chain reaction (RT-PCR). Psychiatry Res. 2010 Apr 30; 176(2-3):99-102. PMID: 20132993.
    View in: PubMed
  55. Henderson DC, Sharma B, Fan X, Copeland PM, Borba CP, Freudenreich O, Cather C, Evins AE, Goff DC. Dietary saturated fat intake and glucose metabolism impairments in nondiabetic, nonobese patients with schizophrenia on clozapine or risperidone. Ann Clin Psychiatry. 2010 Feb; 22(1):33-42. PMID: 20196981.
    View in: PubMed
  56. Freudenreich O, Henderson DC, Macklin EA, Evins AE, Fan X, Cather C, Walsh JP, Goff DC. Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial. J Clin Psychiatry. 2009 Dec; 70(12):1674-80. PMID: 19689921.
    View in: PubMed
  57. Henderson DC, Fan X, Sharma B, Copeland PM, Borba CP, Freudenreich O, Cather C, Evins AE, Goff DC. Waist circumference is the best anthropometric predictor for insulin resistance in nondiabetic patients with schizophrenia treated with clozapine but not olanzapine. J Psychiatr Pract. 2009 Jul; 15(4):251-61. PMID: 19625881.
    View in: PubMed
  58. Henderson DC, Fan X, Copeland PM, Sharma B, Borba CP, Boxill R, Freudenreich O, Cather C, Evins AE, Goff DC. Aripiprazole added to overweight and obese olanzapine-treated schizophrenia patients. J Clin Psychopharmacol. 2009 Apr; 29(2):165-9. PMID: 19512978.
    View in: PubMed
  59. Henderson DC, Fan X, Copeland PM, Sharma B, Borba CP, Forstbauer SI, Miley K, Boxill R, Freudenreich O, Cather C, Evins AE, Goff DC. Ziprasidone as an adjuvant for clozapine- or olanzapine-associated medical morbidity in chronic schizophrenia. Hum Psychopharmacol. 2009 Apr; 24(3):225-32. PMID: 19283774.
    View in: PubMed
  60. Henderson DC, Fan X, Sharma B, Copeland PM, Borba CP, Boxill R, Freudenreich O, Cather C, Eden Evins A, Goff DC. A double-blind, placebo-controlled trial of rosiglitazone for clozapine-induced glucose metabolism impairment in patients with schizophrenia. Acta Psychiatr Scand. 2009 Jun; 119(6):457-65. PMID: 19183127.
    View in: PubMed
  61. Roffman JL, Weiss AP, Deckersbach T, Freudenreich O, Henderson DC, Wong DH, Halsted CH, Goff DC. Interactive effects of COMT Val108/158Met and MTHFR C677T on executive function in schizophrenia. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5; 147B(6):990-5. PMID: 18186041.
    View in: PubMed
  62. Goff DC, Cather C, Freudenreich O, Henderson DC, Evins AE, Culhane MA, Walsh JP. A placebo-controlled study of sildenafil effects on cognition in schizophrenia. Psychopharmacology (Berl). 2009 Jan; 202(1-3):411-7. PMID: 18716761.
    View in: PubMed
  63. Sharma B, Henderson DC. Sibutramine: current status as an anti-obesity drug and its future perspectives. Expert Opin Pharmacother. 2008 Aug; 9(12):2161-73. PMID: 18671470.
    View in: PubMed
  64. Fan X, Henderson DC, Nguyen DD, Cather C, Freudenreich O, Evins AE, Borba CP, Goff DC. Posttraumatic stress disorder, cognitive function and quality of life in patients with schizophrenia. Psychiatry Res. 2008 May 30; 159(1-2):140-6. PMID: 18423611.
    View in: PubMed
  65. Henderson DC. Managing weight gain and metabolic issues in patients treated with atypical antipsychotics. J Clin Psychiatry. 2008 Feb; 69(2):e04. PMID: 18363448.
    View in: PubMed
  66. Henderson DC, Doraiswamy PM. Prolactin-related and metabolic adverse effects of atypical antipsychotic agents. J Clin Psychiatry. 2008; 69 Suppl 1:32-44. PMID: 18484806.
    View in: PubMed
  67. Henderson DC. Considerations for inpatient versus outpatient treatment with antipsychotics. CNS Spectr. 2007 Dec; 12(12 Suppl 21):3-5. PMID: 18389922.
    View in: PubMed
  68. Freudenreich O, Gandhi RT, Walsh JP, Henderson DC, Goff DC. Hepatitis C in schizophrenia: screening experience in a community-dwelling clozapine cohort. Psychosomatics. 2007 Sep-Oct; 48(5):405-11. PMID: 17878499.
    View in: PubMed
  69. Evins AE, Cather C, Culhane MA, Birnbaum A, Horowitz J, Hsieh E, Freudenreich O, Henderson DC, Schoenfeld DA, Rigotti NA, Goff DC. A 12-week double-blind, placebo-controlled study of bupropion sr added to high-dose dual nicotine replacement therapy for smoking cessation or reduction in schizophrenia. J Clin Psychopharmacol. 2007 Aug; 27(4):380-6. PMID: 17632223.
    View in: PubMed
  70. Fan X, Goff DC, Henderson DC. Inflammation and schizophrenia. Expert Rev Neurother. 2007 Jul; 7(7):789-96. PMID: 17610386.
    View in: PubMed
  71. Fan X, Henderson DC, Chiang E, Briggs LB, Freudenreich O, Evins AE, Cather C, Goff DC. Sexual functioning, psychopathology and quality of life in patients with schizophrenia. Schizophr Res. 2007 Aug; 94(1-3):119-27. PMID: 17590315.
    View in: PubMed
  72. Roffman JL, Weiss AP, Purcell S, Caffalette CA, Freudenreich O, Henderson DC, Bottiglieri T, Wong DH, Halsted CH, Goff DC. Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia. Biol Psychiatry. 2008 Jan 1; 63(1):42-8. PMID: 17543893.
    View in: PubMed
  73. Henderson DC, Cagliero E, Copeland PM, Louie PM, Borba CP, Fan X, Freudenreich O, Goff DC. Elevated hemoglobin A1c as a possible indicator of diabetes mellitus and diabetic ketoacidosis in schizophrenia patients receiving atypical antipsychotics. J Clin Psychiatry. 2007 Apr; 68(4):533-41. PMID: 17474808.
    View in: PubMed
  74. Roffman JL, Weiss AP, Deckersbach T, Freudenreich O, Henderson DC, Purcell S, Wong DH, Halsted CH, Goff DC. Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on executive function in schizophrenia. Schizophr Res. 2007 May; 92(1-3):181-8. PMID: 17344026.
    View in: PubMed
  75. Freudenreich O, Henderson DC, Walsh JP, Culhane MA, Goff DC. Risperidone augmentation for schizophrenia partially responsive to clozapine: a double-blind, placebo-controlled trial. Schizophr Res. 2007 May; 92(1-3):90-4. PMID: 17321111.
    View in: PubMed
  76. Henderson DC, Fan X, Copeland PM, Borba CP, Daley TB, Nguyen DD, Zhang H, Hayden D, Freudenreich O, Cather C, Evins AE, Goff DC. A double-blind, placebo-controlled trial of sibutramine for clozapine-associated weight gain. Acta Psychiatr Scand. 2007 Feb; 115(2):101-5. PMID: 17244173.
    View in: PubMed
  77. Henderson DC. Weight gain with atypical antipsychotics: evidence and insights. J Clin Psychiatry. 2007; 68 Suppl 12:18-26. PMID: 17956152.
    View in: PubMed
  78. Fan X, Pristach C, Liu EY, Freudenreich O, Henderson DC, Goff DC. Elevated serum levels of C-reactive protein are associated with more severe psychopathology in a subgroup of patients with schizophrenia. Psychiatry Res. 2007 Jan 15; 149(1-3):267-71. PMID: 17112596.
    View in: PubMed
  79. Weiss AP, Goff D, Schacter DL, Ditman T, Freudenreich O, Henderson D, Heckers S. Fronto-hippocampal function during temporal context monitoring in schizophrenia. Biol Psychiatry. 2006 Dec 1; 60(11):1268-77. PMID: 17020747.
    View in: PubMed
  80. Fan X, Anderson EJ, Copeland PM, Borba CP, Nguyen DD, Freudenreich O, Goff DC, Henderson DC. Higher fasting serum insulin is associated with increased resting energy expenditure in nondiabetic schizophrenia patients. Biol Psychiatry. 2006 Dec 15; 60(12):1372-7. PMID: 16920075.
    View in: PubMed
  81. Weiss AP, Henderson DC, Weilburg JB, Goff DC, Meigs JB, Cagliero E, Grant RW. Treatment of cardiac risk factors among patients with schizophrenia and diabetes. Psychiatr Serv. 2006 Aug; 57(8):1145-52. PMID: 16870966.
    View in: PubMed
  82. Fan X, Liu E, Pristach C, Goff DC, Henderson DC. Higher fasting serum insulin levels are associated with a better psychopathology profile in acutely ill non-diabetic inpatients with schizophrenia. Schizophr Res. 2006 Sep; 86(1-3):30-5. PMID: 16750348.
    View in: PubMed
  83. Henderson DC, Copeland PM, Borba CP, Daley TB, Nguyen DD, Cagliero E, Evins AE, Zhang H, Hayden DL, Freudenreich O, Cather C, Schoenfeld DA, Goff DC. Glucose metabolism in patients with schizophrenia treated with olanzapine or quetiapine: a frequently sampled intravenous glucose tolerance test and minimal model analysis. J Clin Psychiatry. 2006 May; 67(5):789-97. PMID: 16841629.
    View in: PubMed
  84. Henderson DC, Borba CP, Daley TB, Boxill R, Nguyen DD, Culhane MA, Louie P, Cather C, Eden Evins A, Freudenreich O, Taber SM, Goff DC. Dietary intake profile of patients with schizophrenia. Ann Clin Psychiatry. 2006 Apr-Jun; 18(2):99-105. PMID: 16754415.
    View in: PubMed
  85. Henderson DC, Kunkel L, Nguyen DD, Borba CP, Daley TB, Louie PM, Freudenreich O, Cather C, Evins AE, Goff DC. An exploratory open-label trial of aripiprazole as an adjuvant to clozapine therapy in chronic schizophrenia. Acta Psychiatr Scand. 2006 Feb; 113(2):142-7. PMID: 16423166.
    View in: PubMed
  86. Henderson DC, Copeland PM, Nguyen DD, Borba CP, Cather C, Eden Evins A, Freudenreich O, Baer L, Goff DC. Homocysteine levels and glucose metabolism in non-obese, non-diabetic chronic schizophrenia. Acta Psychiatr Scand. 2006 Feb; 113(2):121-5. PMID: 16423163.
    View in: PubMed
  87. Freudenreich O, Herz L, Deckersbach T, Evins AE, Henderson DC, Cather C, Goff DC. Added donepezil for stable schizophrenia: a double-blind, placebo-controlled trial. Psychopharmacology (Berl). 2005 Sep; 181(2):358-63. PMID: 15778880.
    View in: PubMed
  88. Evins AE, Deckersbach T, Cather C, Freudenreich O, Culhane MA, Henderson DC, Green MF, Schoenfeld DA, Rigotti NA, Goff DC. Independent effects of tobacco abstinence and bupropion on cognitive function in schizophrenia. J Clin Psychiatry. 2005 Sep; 66(9):1184-90. PMID: 16187778.
    View in: PubMed
  89. Henderson DC, Nguyen DD, Copeland PM, Hayden DL, Borba CP, Louie PM, Freudenreich O, Evins AE, Cather C, Goff DC. Clozapine, diabetes mellitus, hyperlipidemia, and cardiovascular risks and mortality: results of a 10-year naturalistic study. J Clin Psychiatry. 2005 Sep; 66(9):1116-21. PMID: 16187768.
    View in: PubMed
  90. Henderson DC, Mollica RF, Tor S, Lavelle J, Culhane MA, Hayden D. Building primary care practitioners' attitudes and confidence in mental health skills in a post-conflict society: a Cambodian example. J Nerv Ment Dis. 2005 Aug; 193(8):551-9. PMID: 16082300.
    View in: PubMed
  91. Evins AE, Cather C, Deckersbach T, Freudenreich O, Culhane MA, Olm-Shipman CM, Henderson DC, Schoenfeld DA, Goff DC, Rigotti NA. A double-blind placebo-controlled trial of bupropion sustained-release for smoking cessation in schizophrenia. J Clin Psychopharmacol. 2005 Jun; 25(3):218-25. PMID: 15876899.
    View in: PubMed
  92. Henderson DC, Copeland PM, Daley TB, Borba CP, Cather C, Nguyen DD, Louie PM, Evins AE, Freudenreich O, Hayden D, Goff DC. A double-blind, placebo-controlled trial of sibutramine for olanzapine-associated weight gain. Am J Psychiatry. 2005 May; 162(5):954-62. PMID: 15863798.
    View in: PubMed
  93. Henderson DC, Louie PM, Koul P, Namey L, Daley TB, Nguyen DD. Modafinil-associated weight loss in a clozapine-treated schizoaffective disorder patient. Ann Clin Psychiatry. 2005 Apr-Jun; 17(2):95-7. PMID: 16075662.
    View in: PubMed
  94. Goff DC, Cather C, Evins AE, Henderson DC, Freudenreich O, Copeland PM, Bierer M, Duckworth K, Sacks FM. Medical morbidity and mortality in schizophrenia: guidelines for psychiatrists. J Clin Psychiatry. 2005 Feb; 66(2):183-94; quiz 147, 273-4. PMID: 15705003.
    View in: PubMed
  95. Henderson DC. Schizophrenia and comorbid metabolic disorders. J Clin Psychiatry. 2005; 66 Suppl 6:11-20. PMID: 16107179.
    View in: PubMed
  96. Henderson DC, Cagliero E, Copeland PM, Borba CP, Evins E, Hayden D, Weber MT, Anderson EJ, Allison DB, Daley TB, Schoenfeld D, Goff DC. Glucose metabolism in patients with schizophrenia treated with atypical antipsychotic agents: a frequently sampled intravenous glucose tolerance test and minimal model analysis. Arch Gen Psychiatry. 2005 Jan; 62(1):19-28. PMID: 15630069.
    View in: PubMed
  97. Goff DC, Herz L, Posever T, Shih V, Tsai G, Henderson DC, Freudenreich O, Evins AE, Yovel I, Zhang H, Schoenfeld D. A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients. Psychopharmacology (Berl). 2005 Apr; 179(1):144-50. PMID: 15502972.
    View in: PubMed
  98. Freudenreich O, Cather C, Evins AE, Henderson DC, Goff DC. Attitudes of schizophrenia outpatients toward psychiatric medications: relationship to clinical variables and insight. J Clin Psychiatry. 2004 Oct; 65(10):1372-6. PMID: 15491241.
    View in: PubMed
  99. Goff DC, Bottiglieri T, Arning E, Shih V, Freudenreich O, Evins AE, Henderson DC, Baer L, Coyle J. Folate, homocysteine, and negative symptoms in schizophrenia. Am J Psychiatry. 2004 Sep; 161(9):1705-8. PMID: 15337665.
    View in: PubMed
  100. Henderson DC, Daley TB, Kunkel L, Rodrigues-Scott M, Koul P, Hayden D. Clozapine and hypertension: a chart review of 82 patients. J Clin Psychiatry. 2004 May; 65(5):686-9. PMID: 15163256.
    View in: PubMed
  101. Evins AE, Cather C, Rigotti NA, Freudenreich O, Henderson DC, Olm-Shipman CM, Goff DC. Two-year follow-up of a smoking cessation trial in patients with schizophrenia: increased rates of smoking cessation and reduction. J Clin Psychiatry. 2004 Mar; 65(3):307-11; quiz 452-3. PMID: 15096068.
    View in: PubMed
  102. Casey DE, Haupt DW, Newcomer JW, Henderson DC, Sernyak MJ, Davidson M, Lindenmayer JP, Manoukian SV, Banerji MA, Lebovitz HE, Hennekens CH. Antipsychotic-induced weight gain and metabolic abnormalities: implications for increased mortality in patients with schizophrenia. J Clin Psychiatry. 2004; 65 Suppl 7:4-18; quiz 19-20. PMID: 15151456.
    View in: PubMed
  103. Lafayette JM, Pirl WF, Henderson DC. Low-dose clozapine and diabetic ketoacidosis. Psychosomatics. 2003 May-Jun; 44(3):249-52. PMID: 12724507.
    View in: PubMed
  104. Mollica RF, Henderson DC, Tor S. Psychiatric effects of traumatic brain injury events in Cambodian survivors of mass violence. Br J Psychiatry. 2002 Oct; 181:339-47. PMID: 12356662.
    View in: PubMed
  105. Tamminga CA, Nemeroff CB, Blakely RD, Brady L, Carter CS, Davis KL, Dingledine R, Gorman JM, Grigoriadis DE, Henderson DC, B Innis RB, Killen J, Laughren TP, McDonald WM, M Murphy GM, Paul SM, Rudorfer MV, Sausville E, Schatzberg AF, Scolnick EM, Suppes T. Developing novel treatments for mood disorders: accelerating discovery. Biol Psychiatry. 2002 Sep 15; 52(6):589-609. PMID: 12361670.
    View in: PubMed
  106. Henderson DC. Diabetes mellitus and other metabolic disturbances induced by atypical antipsychotic agents. Curr Diab Rep. 2002 Apr; 2(2):135-40. PMID: 12643133.
    View in: PubMed
  107. Henderson DC. Atypical antipsychotic-induced diabetes mellitus: how strong is the evidence? CNS Drugs. 2002; 16(2):77-89. PMID: 11825099.
    View in: PubMed
  108. Henderson DC, Ettinger ER. Schizophrenia and diabetes. Int Rev Neurobiol. 2002; 51:481-501. PMID: 12420368.
    View in: PubMed
  109. Henderson DC, Goff DC, Connolly CE, Borba CP, Hayden D. Risperidone added to clozapine: impact on serum prolactin levels. J Clin Psychiatry. 2001 Aug; 62(8):605-8. PMID: 11561931.
    View in: PubMed
  110. Frankle W, Shera D, Berger-Hershkowitz H, Evins A, Connolly C, Goff D, Henderson D. Clozapine-associated reduction in arrest rates of psychotic patients with criminal histories. Am J Psychiatry. 2001 Feb; 158(2):270-4. PMID: 11156810.
    View in: PubMed
  111. Henderson DC, Borba CP. Trimethoprim-sulfamethoxazole and clozapine. Psychiatr Serv. 2001 Jan; 52(1):111-2. PMID: 11141546.
    View in: PubMed
  112. Henderson DC. Clozapine: diabetes mellitus, weight gain, and lipid abnormalities. J Clin Psychiatry. 2001; 62 Suppl 23:39-44. PMID: 11603884.
    View in: PubMed
  113. Henderson DC. Clinical experience with insulin resistance, diabetic ketoacidosis, and type 2 diabetes mellitus in patients treated with atypical antipsychotic agents. J Clin Psychiatry. 2001; 62 Suppl 27:10-4; discussion 40-1. PMID: 11806484.
    View in: PubMed
  114. Henderson DC, Cagliero E, Gray C, Nasrallah RA, Hayden DL, Schoenfeld DA, Goff DC. Clozapine, diabetes mellitus, weight gain, and lipid abnormalities: A five-year naturalistic study. Am J Psychiatry. 2000 Jun; 157(6):975-81. PMID: 10831479.
    View in: PubMed
  115. Borba CP, Henderson DC. Citalopram and clozapine: potential drug interaction. J Clin Psychiatry. 2000 Apr; 61(4):301-2. PMID: 10830154.
    View in: PubMed
  116. Goff DC, Henderson DC, Evins AE, Amico E. A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia. Biol Psychiatry. 1999 Feb 15; 45(4):512-4. PMID: 10071726.
    View in: PubMed
  117. Henderson DC, Nasrallah RA, Goff DC. Switching from clozapine to olanzapine in treatment-refractory schizophrenia: safety, clinical efficacy, and predictors of response. J Clin Psychiatry. 1998 Nov; 59(11):585-8. PMID: 9862604.
    View in: PubMed
  118. Henderson DC, Goff DC. Risperidone as an adjunct to clozapine therapy in chronic schizophrenics. J Clin Psychiatry. 1996 Sep; 57(9):395-7. PMID: 9746446.
    View in: PubMed
  119. Henderson DC, Goff DC. Clozapine for polydipsia and hyponatremia in chronic schizophrenics. Biol Psychiatry. 1994 Dec 1; 36(11):768-70. PMID: 7858074.
    View in: PubMed
  120. Goff DC, Henderson DC, Amico E. Cigarette smoking in schizophrenia: relationship to psychopathology and medication side effects. Am J Psychiatry. 1992 Sep; 149(9):1189-94. PMID: 1503131.
    View in: PubMed
David's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
BU Co-Authors
_
Similar BU People
_
Same Department