David Henderson, MD
Boston University School of Medicine
Dept of Psychiatry
General Psychiatry

MD, University of Massachusetts Medical School

Dr. David Henderson is a leader in the fields of schizophrenia, medical co-morbidity, and global psychiatry. He directs the Chester Pierce Division of Global Psychiatry and the MGH Schizophrenia Clinical and Research Program (SCRP) and is principal investigator and director of the MGH Global Mental Health Clinical Research Fellowship.

His research interests include treatment-resistant schizophrenia, the use of psychopharmacological and antipsychotic agents in the treatment of schizophrenia, and the impact of antipsychotic agents on weight, cardiovascular disease, and lipid and glucose metabolism. Dr. Henderson noticed a high rate of diabetes mellitus (DM) in his clozapine-treated patients. As a result, he developed procedures for screening and early detection of diabetes in this population. Dr. Henderson focused on metabolic effects of atypical antipsychotic agents, the role of serotonin receptors, and augmentation strategies to reduce or reverse metabolic disturbances.

As Director of the SCRP, Dr. Henderson directs a leading center for the study and treatment of schizophrenia worldwide. SCRP combines clinical care, training, and clinical and neuroimaging research, with programs designed to improve long-term health and quality of life of seriously mentally ill patients though a multidisciplinary, collaborative approach with community agencies. ]SCRP has more than 20 studies and clinical trials and has trained numerous clinical researchers, fellows and residents who have pursued successful careers in academic medicine. SCRP consults in diabetes and weight management (Dr. Henderson’s current research area), psychosocial therapy, first-episode psychosis, smoking cessation and other psychosis-related issues.

Boston University School of Medicine

Assistant Dean
Boston University School of Medicine
Diversity & Multicultural Affairs

2014 National Alliance on Mental Illness: Exemplary Psychiatrist Award
2013 MGH Department of Psychiatry: Excellence in Research Mentoring
2012 Partners Healthcare, Inc.: Partners in Excellence Award
2012 MGH/McLean Adult Psychiatry Residency Training Program: Psychopharmacology Supervisor Award
2011 Partners Healthcare, Inc.: Partners in Excellence Award
2010 MGH/McLean Adult Psychiatry Residency Training Program: Psychopharmacology Supervisor Award
2008 Black Enterprise: America’s Leading Doctors
2008 Brockton High School Alumni Association: Distinguished Alumnus Award
2007 Massachusetts General Hospital/McLean Adult Psychiatry Residency Training Program: Psychopharmacology Supervisor Award
2007 American Psychiatric Association: Distinguished Fellow
2007 American Psychiatric Association: Dr. Solomon Carter Fuller Award
2005 Commonwealth of Massachusetts Executive Office of Health and Human Services: Department of Mental Health Distinguished Service Award for Research
2004 Massachusetts Psychiatric Society: Outstanding Psychiatry Award for Clinical Psychiatry
1998 Massachusetts General Hospital, Psychiatry Residency Training Program: Outstanding Teacher Award
1996 Massachusetts General Hospital, Psychiatry Residency Training Program: Honorable Mention, Teacher of the Year Award
1995 Massachusetts General Hospital, Psychiatry Residency Training Program: Bulfinch Award for Excellence in Teaching
1994 YMCA: Black Achievers Award of Greater Boston
1992 National Medical Association (Psychiatry and Behavioral Health Section): Ernest Y. Williams, M.D. Clinical Scholars of Distinction Award
1984 Tufts University: McCune Smith Natural Science Award
1984 Tufts University: Student Affairs Community Award for Outstanding Contribution to Community Life

Health Economics and Health Services Research Planning and Support
05/01/2016 - 08/31/2019 (PI)
VA Boston Healthcare System

05/19/2017 - 05/19/2020 (PI)
Roche TCRC, Inc.

Psychiatric Residency and Psychology Internship
07/01/2003 - 06/30/2018 (PI)

A Randomized, Multi-site, Parallel-group, Rater-blind Study Comparing Response with Aripiprazole …
03/01/2016 - 03/31/2018 (PI)
Montana State University

Yr Title Project-Sub Proj Pubs
2016 The MGH Global Psychiatric Clinical Research Training Program 4T32MH093310-05 22
2014 The MGH Global Psychiatric Clinical Research Training Program 5T32MH093310-03 22
2013 The MGH Global Psychiatric Clinical Research Training Program 5T32MH093310-02 22
2012 The MGH Global Psychiatric Clinical Research Training Program 1T32MH093310-01A1 22
2012 The role of neuronal nitric oxide synthase in a model of peritonitis and sepsis 1ZIACL008047-11 1
2012 A non-injurious assay to study mechanisms of transmission of noxious stimulus 1ZIACL008056-10 1
2012 The effect of aging and sex in nociception 1ZIACL008077-08 2
2012 The role of neuronal nitric oxide on current vocalization thresholds 1ZIACL008078-08 3
2012 Anesthesia for children with rare diseases 1ZIACL009009-05 6
2010 The role of neuronal nitric oxide synthase in a model of peritonitis and sepsis 1ZIACL008047-09 1
Showing 10 of 40 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Jackson JW, Fulchino L, Rogers J, Mogun H, Polinski J, Henderson DC, Schneeweiss S, Fischer MA. "Impact of drug-reimbursement policies on prescribing: A case-study of a newly marketed long-acting injectable antipsychotic among relapsed schizophrenia patients". Pharmacoepidemiol Drug Saf. 2018 Jan; 27(1):95-104. PMID: 29168261.
  2. Nemani KL, Greene MC, Ulloa M, Vincenzi B, Copeland PM, Al-Khadari S, Henderson DC. Clozapine, Diabetes Mellitus, Cardiovascular Risk and Mortality: Results of a 21-year Naturalistic Study in Patients with Schizophrenia and Schizoaffective Disorder. Clin Schizophr Relat Psychoses. 2017 Nov 22. PMID: 29164928.
  3. Halim N, Beard J, Mesic A, Patel A, Henderson D, Hibberd P. Intimate partner violence during pregnancy and perinatal mental disorders in low and lower middle income countries: A systematic review of literature, 1990-2017. Clin Psychol Rev. 2017 Nov 21.View Related Profiles. PMID: 29198412.
  4. Denckla CA, Consedine NS, Spies G, Cherner M, Henderson DC, Koenen KC, Seedat S. Associations between neurocognitive functioning and social and occupational resilience among South African women exposed to childhood trauma. Eur J Psychotraumatol. 2017; 8(1):1394146. PMID: 29163865.
  5. Mehralizade A, Schor S, Coleman CM, Oppenheim CE, Denckla CA, Borba CP, Henderson DC, Wolff J, Crane S, Nettles-Gomez P, Pal A, Milanovic S. Mobile Health Apps in OB-GYN-Embedded Psychiatric Care: Commentary. JMIR Mhealth Uhealth. 2017 Oct 06; 5(10):e152.View Related Profiles. PMID: 28986335.
  6. Levey EJ, Gelaye B, Koenen K, Zhong QY, Basu A, Rondon MB, Sanchez S, Henderson DC, Williams MA. Trauma exposure and post-traumatic stress disorder in a cohort of pregnant Peruvian women. Arch Womens Ment Health. 2017 Sep 13. PMID: 28905129.
  7. Denckla CA, Mancini AD, Consedine NS, Milanovic SM, Basu A, Seedat S, Spies G, Henderson DC, Bonanno GA, Koenen KC. Distinguishing postpartum and antepartum depressive trajectories in a large population-based cohort: the impact of exposure to adversity and offspring gender. Psychol Med. 2017 Sep 11; 1-11.View Related Profiles. PMID: 28889814.
  8. Pino EC, Damus K, Jack B, Henderson D, Milanovic S, Kalesan B. Adolescent socioeconomic status and depressive symptoms in later life: Evidence from structural equation models. J Affect Disord. 2018 Jan 01; 225:702-708.View Related Profiles. PMID: 28917197.
  9. Musyimi CW, Mutiso V, Ndetei DM, Henderson DC, Bunders J. Mental Health Outcomes of Psychosocial Intervention Among Traditional Health Practitioner Depressed Patients in Kenya. Cult Med Psychiatry. 2017 Sep; 41(3):453-465. PMID: 28251478; DOI: 10.1007/s11013-017-9527-x;.
  10. Fan X, Song X, Zhao M, Jarskog LF, Natarajan R, Shukair N, Freudenreich O, Henderson DC, Goff DC. The effect of adjunctive telmisartan treatment on psychopathology and cognition in patients with schizophrenia. Acta Psychiatr Scand. 2017 11; 136(5):465-472. PMID: 28851055.
Showing 10 of 136 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 136 publications over 23 distinct years, with a maximum of 18 publications in 2017

Contact for Mentoring:

720 Harrison Ave
Boston MA 02118
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