Neil Kowall | Profiles RNS

Neil W. Kowall, MD

Emeritus Professor

Boston University Chobanian & Avedisian School of Medicine

Neurology

MD, University of British Columbia
BS, University of British Columbia

Websites

Neurology Faculty

ORCID : 0000-0002-6624-0213

Dr. Neil W. Kowall was born in Calgary, Canada and graduated with his MD from the University of British Columbia. He moved to Boston for postgraduate training in Internal Medicine at the Beth Israel Deaconess Hospital followed by a Neurology residency at Massachusetts General Hospital. After finishing his clinical training, he completed a postdoctoral research fellowship and was appointed Assistant Professor of Neurology at Massachusetts General Hospital and Harvard Medical School. He moved to the VA and Boston University in 1992 where he is currently Professor of Neurology and Pathology, Chief of Neurology at VA Boston Healthcare System, Director of the VA New England Geriatric Research Education and Clinical Center and Director of the NIH-funded Boston University Alzheimer’s Disease Center. He has published over 199 original reports. His major research interests are human neuroanatomy and neuropathology and the use of animal models to test novel therapies for neurodegenerative diseases including Alzheimer’s disease. Dr. Kowall’s research interests include the following: human neuroanatomy, immunocytochemistry and enzyme histochemistry of the brain, neuropathological basis of neurological disorders, animal models of neurological diseases, geriatric neurology, and cognitive decline in the elderly.

Professor
Boston University Chobanian & Avedisian School of Medicine
Pathology & Laboratory Medicine

Director of Alzheimer's Disease Center
Boston University Chobanian & Avedisian School of Medicine
Dean’s Office

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Boston University Alzheimer's Disease Research Center
08/15/2021 - 06/30/2026 (PI of Sub-Project / SP)
PI: Ann C. McKee, MD
NIH/National Institute on Aging
5P30AG072978-03

National Alzheimer's Coordinating Center
07/01/2021 - 05/31/2026 (PI of Sub-Project / SP)
University of Washington NIH NIA
5U24AG072122-03

Multi-center development of a novel diagnostic test for Alzheimer's disease
09/01/2018 - 05/31/2025 (Multi-PI)
PI: Neil W. Kowall, MD
NIH/National Institute on Aging
5R01AG059424-05

National Alzheimer's Coordinating Center - Supp
04/06/2022 - 05/31/2024 (PI of Sub-Project / SP)
University of Washington NIH NIA
5U24AG072122-03

Boston University Alzheimer's Disease Center
07/01/2017 - 06/30/2021 (PI)
NIH/National Institute on Aging
3P30AG013846-23S3

National Alzheimer's Coordinating Center (NACC)
07/01/2015 - 06/30/2021 (Subcontract PI)
University of Washington NIH NIA
3U01AG016976-20S9

Boston University Alzheimer's Disease Center
09/15/2016 - 06/30/2017 (PI)
NIH/National Institute on Aging
3P30AG013846-20S1

Boston University Alzheimer's Disease Core Center
07/01/2014 - 06/30/2017 (PI)
NIH/National Institute on Aging
5P30AG013846-20

Alzheimer's Disease Neuroimaging Initiative
09/30/2010 - 07/31/2016 (Subcontract PI)
University of California, San Diego NIH NIA
5U01AG024904-09

Alzheimer's Disease Neuroimaging Initiative
09/30/2010 - 07/31/2016 (Subcontract PI)
University of California, San Diego NIH NIA
5U01AG024904-09

Showing 10 of 25 results. Show All Results

Title
National Alzheimer's Coordinating Center (NACC) Yr4/5 (PI)
VA Biorespository: Gulf War Veterans Illnesses Biorepository (PI)
VA Biorepository Brain Bank (PI)
VA Biorespository Brain Bank: The National PTSD Brain Bank (PI)
Boston University Alzheimer Disease Core Center (PI)

Yr	Title	Project-Sub Proj	Pubs
2024	Core A: Administrative Core	5P30AG072978-04-9741
2023	Core A: Administrative Core	5P30AG072978-03-9741
2022	Core A: Administrative Core	5P30AG072978-02-9741
2022	Boston University Alzheimer's Disease Research Center	5P30AG072978-02
2022	Multi-center development of a novel diagnostic test for Alzheimer's disease	5R01AG059424-05
2021	Core A: Administrative Core	1P30AG072978-01-9741
2021	Boston University Alzheimer's Disease Research Center	1P30AG072978-01
2021	Multi-center development of a novel diagnostic test for Alzheimer's disease	5R01AG059424-04	2
2020	Multi-center development of a novel diagnostic test for Alzheimer's disease	5R01AG059424-03	2
2020	VA Biorepository: Gulf War Veterans' Illnesses Biorepository	2I01BX003063-05A1

Showing 10 of 118 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Culhane JE, Jackson CE, Tripodis Y, Nowinski CJ, Dams-O'Connor K, Pettway E, Uretsky M, Abdolmohammadi B, Nair E, Martin B, Palmisano J, Katz DI, Dwyer B, Daneshvar DH, Goldstein LE, Kowall NW, Cantu RC, Stern RA, Huber BR, Crary JF, Mez J, Stein TD, McKee AC, Alosco ML. Lack of Association of Informant-Reported Traumatic Brain Injury and Chronic Traumatic Encephalopathy. J Neurotrauma. 2024 Jun; 41(11-12):1399-1408.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Tripodis, Yorghos

PMID: 38445389; PMCID: PMC11339554; DOI: 10.1089/neu.2023.0391;

Alexander A, Alvarez VE, Huber BR, Alosco ML, Mez J, Tripodis Y, Nicks R, Katz DI, Dwyer B, Daneshvar DH, Martin B, Palmisano J, Goldstein LE, Crary JF, Nowinski C, Cantu RC, Kowall NW, Stern RA, Delalle I, McKee AC, Stein TD. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta Neuropathol. 2024 Feb 26; 147(1):45.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Delalle, Ivana
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 38407651; PMCID: PMC11348287; DOI: 10.1007/s00401-024-02690-5;

Alosco ML, White M, Bell C, Faheem F, Tripodis Y, Yhang E, Baucom Z, Martin B, Palmisano J, Dams-O'Connor K, Crary JF, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Huber BR, Stein TD, McKee AC, Mez J. Cognitive, functional, and neuropsychiatric correlates of regional tau pathology in autopsy-confirmed chronic traumatic encephalopathy. Mol Neurodegener. 2024 Feb 06; 19(1):10.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 38317248; PMCID: PMC10845638; DOI: 10.1186/s13024-023-00697-2;

Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, Martin B, Palmisano JN, Steinberg EG, Simkin I, Turk KW, Budson AE, Au R, Farrer L, Jun GR, Kowall NW, Stern RA, Goldstein LE, Qiu WQ, Mez J, Huber BR, Alvarez VE, McKee AC, Zetterberg H, Gobom J, Stein TD, Blennow K. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathol. 2023 Dec 30; 147(1):5.View Related Profiles.

Budson, Andrew
McKee, Ann
Huber, Bertrand
Sconzo, Daniel
Steinberg, Eric
Jun, Gyungah
Aparicio, Hugo
Mez, Jesse
Turk, Katherine
Goldstein, Lee
Farrer, Lindsay
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 38159140; PMCID: PMC10757700; DOI: 10.1007/s00401-023-02660-3;

Ally M, Sugarman MA, Zetterberg H, Blennow K, Ashton NJ, Karikari TK, Aparicio HJ, Frank B, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkin I, Farrer LA, Jun GR, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Kowall NW, Killiany R, Stern RA, Stein TD, McKee AC, Qiu WQ, Mez J, Alosco ML. Cross-sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease. Alzheimers Dement (Amst). 2023; 15(4):e12492.View Related Profiles.

Budson, Andrew
McKee, Ann
Frank, Brandon
Steinberg, Eric
Jun, Gyungah
Aparicio, Hugo
Mez, Jesse
Turk, Katherine
Goldstein, Lee
Farrer, Lindsay
O'Connor, Maureen
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Stein, Thor
Tripodis, Yorghos

PMID: 37885919; PMCID: PMC10599277; DOI: 10.1002/dad2.12492;

McKee AC, Mez J, Abdolmohammadi B, Butler M, Huber BR, Uretsky M, Babcock K, Cherry JD, Alvarez VE, Martin B, Tripodis Y, Palmisano JN, Cormier KA, Kubilus CA, Nicks R, Kirsch D, Mahar I, McHale L, Nowinski C, Cantu RC, Stern RA, Daneshvar D, Goldstein LE, Katz DI, Kowall NW, Dwyer B, Stein TD, Alosco ML. Neuropathologic and Clinical Findings in Young Contact Sport Athletes Exposed to Repetitive Head Impacts. JAMA Neurol. 2023 Oct 01; 80(10):1037-1050.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mahar, Ian
Mez, Jesse
Cherry, Jonathan
Babcock, Katharine
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 37639244; PMCID: PMC10463175; DOI: 10.1001/jamaneurol.2023.2907;

Groechel RC, Tripodis Y, Alosco ML, Mez J, Qiao Qiu W, Goldstein L, Budson AE, Kowall NW, Shaw LM, Weiner M, Jack CR, Killiany RJ. Biomarkers of Alzheimer's disease in Black and/or African American Alzheimer's Disease Neuroimaging Initiative (ADNI) participants. Neurobiol Aging. 2023 Nov; 131:144-152.View Related Profiles.

Budson, Andrew
Mez, Jesse
Alosco, Michael
Kowall, Neil
Tripodis, Yorghos

PMID: 37639768; PMCID: PMC10528881; DOI: 10.1016/j.neurobiolaging.2023.07.021;

Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.View Related Profiles.

McKee, Ann
Jun, Gyungah
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Kowall, Neil
Sherva, Richard
Stern, Robert

PMID: 37461624; PMCID: PMC10350126; DOI: 10.1101/2023.07.06.23292311;

Daneshvar DH, Nair ES, Baucom ZH, Rasch A, Abdolmohammadi B, Uretsky M, Saltiel N, Shah A, Jarnagin J, Baugh CM, Martin BM, Palmisano JN, Cherry JD, Alvarez VE, Huber BR, Weuve J, Nowinski CJ, Cantu RC, Zafonte RD, Dwyer B, Crary JF, Goldstein LE, Kowall NW, Katz DI, Stern RA, Tripodis Y, Stein TD, McClean MD, Alosco ML, McKee AC, Mez J. Leveraging football accelerometer data to quantify associations between repetitive head impacts and chronic traumatic encephalopathy in males. Nat Commun. 2023 Jun 20; 14(1):3470.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Weuve, Jennifer
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
McClean, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 37340004; PMCID: PMC10281995; DOI: 10.1038/s41467-023-39183-0;

Groechel RC, Tripodis Y, Alosco ML, Mez J, Qiu WQ, Mercier G, Goldstein L, Budson AE, Kowall NW, Killiany RJ. Annualized changes in rate of amyloid deposition and neurodegeneration are greater in participants who become amyloid positive than those who remain amyloid negative. Neurobiol Aging. 2023 Jul; 127:33-42.View Related Profiles.

Budson, Andrew
Mercier, Gustavo
Mez, Jesse
Alosco, Michael
Kowall, Neil
Qiu, Wendy
Tripodis, Yorghos

PMID: 37043881

Showing 10 of 272 results. Show More

Alosco ML, Ly M, Mosaheb S, Saltiel N, Uretsky M, Tripodis Y, Martin B, Palmisano J, Delano-Wood L, Bondi MW, Meng G, Xia W, Daley S, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Stern RA, Alvarez VE, Mez J, Huber BR, McKee AC, Stein TD. Decreased myelin proteins in brain donors exposed to football-related repetitive head impacts. Brain Commun. 2023; 5(2):fcad019.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Ly, Monica
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 36895961; PMCID: PMC9990992; DOI: 10.1093/braincomms/fcad019;

Choi SH, Yousefian-Jazi A, Hyeon SJ, Nguyen PTT, Chu J, Kim S, Kim S, Ryu HL, Kowall NW, Ryu H, Lee J. Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS. J Biomed Sci. 2022 Dec 20; 29(1):106.View Related Profiles.

Ryu, Hoon
Lee, Junghee
Kowall, Neil

PMID: 36536341; PMCID: PMC9764677; DOI: 10.1186/s12929-022-00890-3;

Morrison MS, Aparicio HJ, Blennow K, Zetterberg H, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Sugarman MA, Frank B, Steinberg EG, Turk KW, Budson AE, Au R, Goldstein LE, Jun GR, Kowall NW, Killiany R, Qiu WQ, Stern RA, Mez J, McKee AC, Stein TD, Alosco ML. Ante-mortem plasma phosphorylated tau (181) predicts Alzheimer's disease neuropathology and regional tau at autopsy. Brain. 2022 Oct 21; 145(10):3546-3557.View Related Profiles.

Budson, Andrew
McKee, Ann
Frank, Brandon
Steinberg, Eric
Jun, Gyungah
Aparicio, Hugo
Mez, Jesse
Turk, Katherine
Goldstein, Lee
Morrison, Madeline
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Qiu, Wendy
Tripodis, Yorghos

PMID: 35554506; PMCID: PMC10233293; DOI: 10.1093/brain/awac175;

Atherton K, Han X, Chung J, Cherry JD, Baucom Z, Saltiel N, Nair E, Abdolmohammadi B, Uretsky M, Khan MM, Shea C, Durape S, Martin BM, Palmisano JN, Farrell K, Nowinski CJ, Alvarez VE, Dwyer B, Daneshvar DH, Katz DI, Goldstein LE, Cantu RC, Kowall NW, Alosco ML, Huber BR, Tripodis Y, Crary JF, Farrer L, Stern RA, Stein TD, McKee AC, Mez J. Association of APOE Genotypes and Chronic Traumatic Encephalopathy. JAMA Neurol. 2022 Aug 01; 79(8):787-796.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Chung, Jaeyoon
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Farrer, Lindsay
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 35759276; PMCID: PMC9237800; DOI: 10.1001/jamaneurol.2022.1634;

Colvin LE, Foster ZW, Stein TD, Thakore-James M, Salajegheh MK, Carr K, Spencer KR, Abdul Rauf N, Adams L, Averill JG, Walker SE, Robey I, Alvarez VE, Huber BR, McKee AC, Kowall NW, Brady CB. Utility of the ALSFRS-R for predicting ALS and comorbid disease neuropathology: The Veterans Affairs Biorepository Brain Bank. Muscle Nerve. 2022 Aug; 66(2):167-174.View Related Profiles.

McKee, Ann
Huber, Bertrand
Brady, Christopher
Thakore-James, Manisha
Salajegheh, Mohammad
Kowall, Neil
Stein, Thor
Alvarez, Victor

PMID: 35585776; PMCID: PMC9308705; DOI: 10.1002/mus.27635;

Alvia M, Aytan N, Spencer KR, Foster ZW, Rauf NA, Guilderson L, Robey I, Averill JG, Walker SE, Alvarez VE, Huber BR, Mathais R, Cormier KA, Nicks R, Pothast M, Labadorf A, Agus F, Alosco ML, Mez J, Kowall NW, McKee AC, Brady CB, Stein TD. MicroRNA Alterations in Chronic Traumatic Encephalopathy and Amyotrophic Lateral Sclerosis. Front Neurosci. 2022; 16:855096.View Related Profiles.

Labadorf, Adam
McKee, Ann
Huber, Bertrand
Brady, Christopher
Mez, Jesse
Alosco, Michael
Kowall, Neil
Aytan, Nurgul
Stein, Thor
Alvarez, Victor

PMID: 35663558; PMCID: PMC9160996; DOI: 10.3389/fnins.2022.855096;

Frank B, Ally M, Tripodis Y, Puzo C, Labriolo C, Hurley L, Martin B, Palmisano J, Chan L, Steinberg E, Turk K, Budson A, O'Connor M, Au R, Qiu WQ, Goldstein L, Kukull W, Kowall N, Killiany R, Stern R, Stein T, McKee A, Mez J, Alosco M. Trajectories of Cognitive Decline in Brain Donors With Autopsy-Confirmed Alzheimer Disease and Cerebrovascular Disease. Neurology. 2022 Jun 14; 98(24):e2454-e2464.View Related Profiles.

Budson, Andrew
McKee, Ann
Frank, Brandon
Steinberg, Eric
Mez, Jesse
Turk, Katherine
Goldstein, Lee
O'Connor, Maureen
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 35444054; PMCID: PMC9231841; DOI: 10.1212/WNL.0000000000200304;

Turk KW, Geada A, Alvarez VE, Xia W, Cherry JD, Nicks R, Meng G, Daley S, Tripodis Y, Huber BR, Budson AE, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, Alosco ML, Mez J, McKee AC, Stein TD. A comparison between tau and amyloid-ß cerebrospinal fluid biomarkers in chronic traumatic encephalopathy and Alzheimer disease. Alzheimers Res Ther. 2022 02 09; 14(1):28.View Related Profiles.

Budson, Andrew
McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Katz, Douglas
Mez, Jesse
Cherry, Jonathan
Turk, Katherine
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Xia, Weiming
Tripodis, Yorghos

PMID: 35139894; PMCID: PMC8830027; DOI: 10.1186/s13195-022-00976-y;

Alosco ML, Mian AZ, Buch K, Farris CW, Uretsky M, Tripodis Y, Baucom Z, Martin B, Palmisano J, Puzo C, Ang TFA, Joshi P, Goldstein LE, Au R, Katz DI, Dwyer B, Daneshvar DH, Nowinski C, Cantu RC, Kowall NW, Huber BR, Alvarez VE, Stern RA, Stein TD, Killiany RJ, McKee AC, Mez J. Structural MRI profiles and tau correlates of atrophy in autopsy-confirmed CTE. Alzheimers Res Ther. 2021 12 07; 13(1):193.View Related Profiles.

McKee, Ann
Mian, Asim
Huber, Bertrand
Dwyer, Brigid
Farris, Chad
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Ang, Ting Fang Alvin
Alvarez, Victor
Tripodis, Yorghos

PMID: 34876229; PMCID: PMC8653514; DOI: 10.1186/s13195-021-00928-y;

Frank B, Ally M, Brekke B, Zetterberg H, Blennow K, Sugarman MA, Ashton NJ, Karikari TK, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Simkina I, Turk KW, Budson AE, O'Connor MK, Au R, Goldstein LE, Jun GR, Kowall NW, Stein TD, McKee AC, Killiany R, Qiu WQ, Stern RA, Mez J, Alosco ML. Plasma p-tau181 shows stronger network association to Alzheimer's disease dementia than neurofilament light and total tau. Alzheimers Dement. 2022 Aug; 18(8):1523-1536.View Related Profiles.

Budson, Andrew
McKee, Ann
Frank, Brandon
Steinberg, Eric
Jun, Gyungah
Mez, Jesse
Turk, Katherine
Goldstein, Lee
O'Connor, Maureen
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 34854549; PMCID: PMC9160800; DOI: 10.1002/alz.12508;

Uretsky M, Bouix S, Killiany RJ, Tripodis Y, Martin B, Palmisano J, Mian AZ, Buch K, Farris C, Daneshvar DH, Dwyer B, Goldstein L, Katz D, Nowinski C, Cantu R, Kowall N, Huber BR, Stern RA, Alvarez VE, Stein TD, McKee A, Mez J, Alosco ML. Association Between Antemortem FLAIR White Matter Hyperintensities and Neuropathology in Brain Donors Exposed to Repetitive Head Impacts. Neurology. 2022 01 04; 98(1):e27-e39.View Related Profiles.

McKee, Ann
Mian, Asim
Huber, Bertrand
Dwyer, Brigid
Farris, Chad
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mez, Jesse
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Killiany, Ronald
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 34819338; PMCID: PMC8726571; DOI: 10.1212/WNL.0000000000013012;

Brady CB, Robey I, Stein TD, Huber BR, Riley J, Abdul Rauf N, Spencer KR, Walt G, Adams L, Averill JG, Walker S, McKee AC, Thomson SP, Kowall NW. The Department of Veterans Affairs Gulf War Veterans' Illnesses Biorepository: Supporting Research on Gulf War Veterans' Illnesses. Brain Sci. 2021 Oct 14; 11(10).View Related Profiles.

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PMID: 34679413; PMCID: PMC8533803; DOI: 10.3390/brainsci11101349;

Johnson JO, Chia R, Miller DE, Li R, Kumaran R, Abramzon Y, Alahmady N, Renton AE, Topp SD, Gibbs JR, Cookson MR, Sabir MS, Dalgard CL, Troakes C, Jones AR, Shatunov A, Iacoangeli A, Al Khleifat A, Ticozzi N, Silani V, Gellera C, Blair IP, Dobson-Stone C, Kwok JB, Bonkowski ES, Palvadeau R, Tienari PJ, Morrison KE, Shaw PJ, Al-Chalabi A, Brown RH, Calvo A, Mora G, Al-Saif H, Gotkine M, Leigh F, Chang IJ, Perlman SJ, Glass I, Scott AI, Shaw CE, Basak AN, Landers JE, Chiò A, Crawford TO, Smith BN, Traynor BJ, Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp SD, Scotter EL, Kenna KP, Keagle P, Tiloca C, Vance C, Troakes C, Colombrita C, King A, Pensato V, Castellotti B, Baas F, Ten Asbroek ALMA, McKenna-Yasek D, McLaughlin RL, Polak M, Asress S, Esteban-Pérez J, Stevic Z, D'Alfonso S, Mazzini L, Comi GP, Del Bo R, Ceroni M, Gagliardi S, Querin G, Bertolin C, van Rheenen W, Rademakers R, van Blitterswijk M, Lauria G, Duga S, Corti S, Cereda C, Corrado L, Sorarù G, Williams KL, Nicholson GA, Blair IP, Leblond-Manry C, Rouleau GA, Hardiman O, Morrison KE, Veldink JH, van den Berg LH, Al-Chalabi A, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, García-Redondo A, Wu Z, Glass JD, Gellera C, Ratti A, Brown RH, Silani V, Shaw CE, Landers JE, Dalgard CL, Adeleye A, Soltis AR, Alba C, Viollet C, Bacikova D, Hupalo DN, Sukumar G, Pollard HB, Wilkerson MD, Martinez EM, Abramzon Y, Ahmed S, Arepalli S, Baloh RH, Bowser R, Brady CB, Brice A, Broach J, Campbell RH, Camu W, Chia R, Cooper-Knock J, Ding J, Drepper C, Drory VE, Dunckley TL, Eicher JD, England BK, Faghri F, Feldman E, Floeter MK, Fratta P, Geiger JT, Gerhard G, Gibbs JR, Gibson SB, Glass JD, Hardy J, Harms MB, Heiman-Patterson TD, Hernandez DG, Jansson L, Kirby J, Kowall NW, Laaksovirta H, Landeck N, Landi F, Le Ber I, Lumbroso S, MacGowan DJL, Maragakis NJ, Mora G, Mouzat K, Murphy NA, Myllykangas L, Nalls MA, Orrell RW, Ostrow LW, Pamphlett R, Pickering-Brown S, Pioro EP, Pletnikova O, Pliner HA, Pulst SM, Ravits JM, Renton AE, Rivera A, Robberecht W, Rogaeva E, Rollinson S, Rothstein JD, Scholz SW, Sendtner M, Shaw PJ, Sidle KC, Simmons Z, Singleton AB, Smith N, Stone DJ, Tienari PJ, Troncoso JC, Valori M, Van Damme P, Van Deerlin VM, Van Den Bosch L, Zinman L, Landers JE, Chiò A, Traynor BJ, Angelocola SM, Ausiello FP, Barberis M, Bartolomei I, Battistini S, Bersano E, Bisogni G, Borghero G, Brunetti M, Cabona C, Calvo A, Canale F, Canosa A, Cantisani TA, Capasso M, Caponnetto C, Cardinali P, Carrera P, Casale F, Chiò A, Colletti T, Conforti FL, Conte A, Conti E, Corbo M, Cuccu S, Dalla Bella E, D'Errico E, DeMarco G, Dubbioso R, Ferrarese C, Ferraro PM, Filippi M, Fini N, Floris G, Fuda G, Gallone S, Gianferrari G, Giannini F, Grassano M, Greco L, Iazzolino B, Introna A, La Bella V, Lattante S, Lauria G, Liguori R, Logroscino G, Logullo FO, Lunetta C, Mandich P, Mandrioli J, Manera U, Manganelli F, Marangi G, Marinou K, Marrosu MG, Martinelli I, Messina S, Moglia C, Mora G, Mosca L, Murru MR, Origone P, Passaniti C, Petrelli C, Petrucci A, Pozzi S, Pugliatti M, Quattrini A, Ricci C, Riolo G, Riva N, Russo M, Sabatelli M, Salamone P, Salivetto M, Salvi F, Santarelli M, Sbaiz L, Sideri R, Simone I, Simonini C, Spataro R, Tanel R, Tedeschi G, Ticca A, Torriello A, Tranquilli S, Tremolizzo L, Trojsi F, Vasta R, Vacchiano V, Vita G, Volanti P, Zollino M, Zucchi E. Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis. JAMA Neurol. 2021 10 01; 78(10):1236-1248.View Related Profiles.

Brady, Christopher
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PMID: 34459874; PMCID: PMC8406220; DOI: 10.1001/jamaneurol.2021.2598;

Alosco ML, Mariani ML, Adler CH, Balcer LJ, Bernick C, Au R, Banks SJ, Barr WB, Bouix S, Cantu RC, Coleman MJ, Dodick DW, Farrer LA, Geda YE, Katz DI, Koerte IK, Kowall NW, Lin AP, Marcus DS, Marek KL, McClean MD, McKee AC, Mez J, Palmisano JN, Peskind ER, Tripodis Y, Turner RW, Wethe JV, Cummings JL, Reiman EM, Shenton ME, Stern RA. Developing methods to detect and diagnose chronic traumatic encephalopathy during life: rationale, design, and methodology for the DIAGNOSE CTE Research Project. Alzheimers Res Ther. 2021 08 12; 13(1):136.View Related Profiles.

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PMID: 34384490; PMCID: PMC8357968; DOI: 10.1186/s13195-021-00872-x;

Hyeon SJ, Park J, Yoo J, Kim SH, Hwang YJ, Kim SC, Liu T, Shim HS, Kim Y, Cho Y, Woo J, Kim KS, Myers RH, Ryu HL, Kowall NW, Song EJ, Hwang EM, Seo H, Lee J, Ryu H. Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington's disease. Prog Neurobiol. 2021 09; 204:102110.View Related Profiles.

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PMID: 34166773; PMCID: PMC8364511; DOI: 10.1016/j.pneurobio.2021.102110;

Mez J, Alosco ML, Daneshvar DH, Saltiel N, Baucom Z, Abdolmohammadi B, Uretsky M, Nicks R, Martin BM, Palmisano JN, Nowinski CJ, Montenigro P, Solomon TM, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Goldstein LE, Katz DI, Cantu RC, Kowall NW, Tripodis Y, Huber BR, Stein TD, Stern RA, McKee AC. Validity of the 2014 traumatic encephalopathy syndrome criteria for CTE pathology. Alzheimers Dement. 2021 10; 17(10):1709-1724.View Related Profiles.

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Montenigro, Philip
Stern, Robert
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PMID: 33826224; PMCID: PMC8596795; DOI: 10.1002/alz.12338;

Greco FA, McKee AC, Kowall NW, Hanlon EB. Near-Infrared Optical Spectroscopy In Vivo Distinguishes Subjects with Alzheimer's Disease from Age-Matched Controls. J Alzheimers Dis. 2021; 82(2):791-802.View Related Profiles.

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PMID: 34092628; PMCID: PMC8385529; DOI: 10.3233/JAD-201021;

Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 01 01; 78(1):102-113.View Related Profiles.

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PMID: 33074286; PMCID: PMC7573798; DOI: 10.1001/jamaneurol.2020.3536;

Alosco ML, Tripodis Y, Rowland B, Chua AS, Liao H, Martin B, Jarnagin J, Chaisson CE, Pasternak O, Karmacharya S, Koerte IK, Cantu RC, Kowall NW, McKee AC, Shenton ME, Greenwald R, McClean M, Stern RA, Lin A. A magnetic resonance spectroscopy investigation in symptomatic former NFL players. Brain Imaging Behav. 2020 Oct; 14(5):1419-1429.View Related Profiles.

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PMID: 30848432; PMCID: PMC6994233; DOI: 10.1007/s11682-019-00060-4;

Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 12; 140(6):851-862.View Related Profiles.

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Kowall, Neil
Aytan, Nurgul
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 32939646; PMCID: PMC7669574; DOI: 10.1007/s00401-020-02206-x;

Alosco ML, Cherry JD, Huber BR, Tripodis Y, Baucom Z, Kowall NW, Saltiel N, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Palmisano JN, Martin B, Cantu RC, Stern RA, Alvarez VE, Mez J, Stein TD, McKee AC. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme. Acta Neuropathol. 2020 10; 140(4):495-512.View Related Profiles.

McKee, Ann
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Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 32778942; PMCID: PMC7914059; DOI: 10.1007/s00401-020-02197-9;

Spencer KR, Foster ZW, Rauf NA, Guilderson L, Collins D, Averill JG, Walker SE, Robey I, Cherry JD, Alvarez VE, Huber BR, McKee AC, Kowall NW, Brady CB, Stein TD. Neuropathological profile of long-duration amyotrophic lateral sclerosis in military Veterans. Brain Pathol. 2020 11; 30(6):1028-1040.View Related Profiles.

McKee, Ann
Huber, Bertrand
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PMID: 32633852; PMCID: PMC8018169; DOI: 10.1111/bpa.12876;

Cho H, Hyeon SJ, Shin JY, Alvarez VE, Stein TD, Lee J, Kowall NW, McKee AC, Ryu H, Seo JS. Alterations of transcriptome signatures in head trauma-related neurodegenerative disorders. Sci Rep. 2020 06 01; 10(1):8811.View Related Profiles.

McKee, Ann
Ryu, Hoon
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Stein, Thor
Alvarez, Victor

PMID: 32483284; PMCID: PMC7264177; DOI: 10.1038/s41598-020-65916-y;

Sugarman MA, Zetterberg H, Blennow K, Tripodis Y, McKee AC, Stein TD, Martin B, Palmisano JN, Steinberg EG, Simkin I, Budson AE, Killiany R, O'Connor MK, Au R, Qiu WWQ, Goldstein LE, Kowall NW, Mez J, Stern RA, Alosco ML. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiol Aging. 2020 10; 94:60-70.View Related Profiles.

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Killiany, Ronald
Stein, Thor
Qiu, Wendy
Tripodis, Yorghos

PMID: 32585491; PMCID: PMC7484086; DOI: 10.1016/j.neurobiolaging.2020.05.011;

Lee MY, Lee J, Hyeon SJ, Cho H, Hwang YJ, Shin JY, McKee AC, Kowall NW, Kim JI, Stein TD, Hwang D, Ryu H. Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease. Aging Cell. 2020 06; 19(6):e13153.View Related Profiles.

McKee, Ann
Ryu, Hoon
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PMID: 32419307; PMCID: PMC7294781; DOI: 10.1111/acel.13153;

Shin S, Kim D, Song JY, Jeong H, Hyeon SJ, Kowall NW, Ryu H, Pae AN, Lim S, Kim YK. Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathy. Prog Neurobiol. 2020 Feb 24; 101782.View Related Profiles.

Ryu, Hoon
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PMID: 32105751

Heo JY, Nam MH, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park HJ, Jo S, Lee MJ, Kim S, Shim JE, Jang DP, Kim KI, Huh SH, Jeong JY, Kowall NW, Lee J, Im H, Park JH, Jang BK, Park KD, Lee HJ, Shin H, Cho IJ, Hwang EM, Kim Y, Kim HY, Oh SJ, Lee SE, Paek SH, Yoon JH, Jin BK, Kweon GR, Shim I, Hwang O, Ryu H, Jeon SR, Lee CJ. Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease. Curr Biol. 2020 01 20; 30(2):276-291.e9.View Related Profiles.

Ryu, Hoon
Lee, Junghee
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PMID: 31928877

Pelcher I, Puzo C, Tripodis Y, Aparicio HJ, Steinberg EG, Phelps A, Martin B, Palmisano JN, Vassey E, Lindbergh C, McKee AC, Stein TD, Killiany RJ, Au R, Kowall NW, Stern RA, Mez J, Alosco ML. Revised Framingham Stroke Risk Profile: Association with Cognitive Status and MRI-Derived Volumetric Measures. J Alzheimers Dis. 2020; 78(4):1393-1408.View Related Profiles.

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Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 33164933; PMCID: PMC7887636; DOI: 10.3233/JAD-200803;

Mez J, Daneshvar DH, Abdolmohammadi B, Chua AS, Alosco ML, Kiernan PT, Evers L, Marshall L, Martin BM, Palmisano JN, Nowinski CJ, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Huber BR, Stein TD, Goldstein LE, Katz DI, Cantu RC, Au R, Kowall NW, Stern RA, McClean MD, Weuve J, Tripodis Y, McKee AC. Duration of American Football Play and Chronic Traumatic Encephalopathy. Ann Neurol. 2020 01; 87(1):116-131.View Related Profiles.

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Huber, Bertrand
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Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
McClean, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 31589352; PMCID: PMC6973077; DOI: 10.1002/ana.25611;

Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy. JAMA Neurol. 2019 Nov 01; 76(11):1298-1308.View Related Profiles.

McKee, Ann
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Katz, Douglas
Mahar, Ian
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Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 31380975; PMCID: PMC6686769; DOI: 10.1001/jamaneurol.2019.2244;

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. Author CoView Related Profiles.

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Sarnowski, Chloe
Jun, Gyungah
Himali, Jayandra
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil
Yang, Qiong
Stern, Robert
Seshadri, Sudha

PMID: 31417202; PMCID: PMC7265117; DOI: 10.1038/s41588-019-0495-7;

Carreras I, Aytan N, Choi JK, Tognoni CM, Kowall NW, Jenkins BG, Dedeoglu A. Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease. Sci Rep. 2019 07 29; 9(1):10972.View Related Profiles.

Dedeoglu, Alpaslan
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PMID: 31358793; PMCID: PMC6662857; DOI: 10.1038/s41598-019-47287-1;

Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML. Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set. Alzheimers Res Ther. 2019 07 27; 11(1):64.View Related Profiles.

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Steinberg, Eric
Mez, Jesse
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Stein, Thor
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PMID: 31351489; PMCID: PMC6661103; DOI: 10.1186/s13195-019-0521-0;

Bi B, Choi HP, Hyeon SJ, Sun S, Su N, Liu Y, Lee J, Kowall NW, McKee AC, Yang JH, Ryu H. Quantitative Proteomic Analysis Reveals Impaired Axonal Guidance Signaling in Human Postmortem Brain Tissues of Chronic Traumatic Encephalopathy. Exp Neurobiol. 2019 Jun; 28(3):362-375.View Related Profiles.

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Lee, Junghee
Kowall, Neil

PMID: 31308796; PMCID: PMC6614068; DOI: 10.5607/en.2019.28.3.362;

Kim YH, Shim HS, Kim KH, Lee J, Chung BC, Kowall NW, Ryu H, Lee J. Metabolomic Analysis Identifies Alterations of Amino Acid Metabolome Signatures in the Postmortem Brain of Alzheimer's Disease. Exp Neurobiol. 2019 Jun; 28(3):376-389.View Related Profiles.

Ryu, Hoon
Lee, Junghee
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PMID: 31308797; PMCID: PMC6614073; DOI: 10.5607/en.2019.28.3.376;

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PMID: 31183671; PMCID: PMC6689453; DOI: 10.1007/s00401-019-02031-x;

Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia. Alzheimers Dement. 2019 05; 15(5):686-698.View Related Profiles.

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PMID: 30852157; PMCID: PMC6511462; DOI: 10.1016/j.jalz.2018.12.015;

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PMID: 30820047; PMCID: PMC6463297; DOI: 10.1038/s41588-019-0358-2;

Walt GS, Burris HM, Brady CB, Spencer KR, Alvarez VE, Huber BR, Guilderson L, Abdul Rauf N, Collins D, Singh T, Mathias R, Averill JG, Walker SE, Robey I, McKee AC, Kowall NW, Stein TD. Chronic Traumatic Encephalopathy Within an Amyotrophic Lateral Sclerosis Brain Bank Cohort. J Neuropathol Exp Neurol. 2018 12 01; 77(12):1091-1100.View Related Profiles.

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PMID: 30299493; PMCID: PMC6927868; DOI: 10.1093/jnen/nly092;

Korkmaz OT, Ay H, Aytan N, Carreras I, Kowall NW, Dedeoglu A, Tuncel N. Vasoactive Intestinal Peptide Decreases ß-Amyloid Accumulation and Prevents Brain Atrophy in the 5xFAD Mouse Model of Alzheimer's Disease. J Mol Neurosci. 2019 Jul; 68(3):389-396.View Related Profiles.

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PMID: 30498985

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PMID: 30390709; PMCID: PMC6215686; DOI: 10.1186/s40478-018-0619-9;

Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports. J Neuropathol Exp Neurol. 2018 09 01; 77(9):757-768.View Related Profiles. PMID: 30053297; PMCID: PMC6097837; DOI: 10.1093/jnen/nly065;

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PMID: 29126099; PMCID: PMC6116785; DOI: 10.1093/arclin/acx100;

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PMID: 29710395; PMCID: PMC6367933; DOI: 10.1002/ana.25245;

Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Shankaracharya, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L, Moreno CAM, Kamalakaran S, Goldstein DB, Gitler AD, Harris T, Myers RM, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chiò A, Shaw CE, Traynor BJ, Landers JE. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 2018 03 21; 97(6):1268-1283.e6.View Related Profiles.

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PMID: 29566793; PMCID: PMC5867896; DOI: 10.1016/j.neuron.2018.02.027;

Tagge CA, Fisher AM, Minaeva OV, Gaudreau-Balderrama A, Moncaster JA, Zhang XL, Wojnarowicz MW, Casey N, Lu H, Kokiko-Cochran ON, Saman S, Ericsson M, Onos KD, Veksler R, Senatorov VV, Kondo A, Zhou XZ, Miry O, Vose LR, Gopaul KR, Upreti C, Nowinski CJ, Cantu RC, Alvarez VE, Hildebrandt AM, Franz ES, Konrad J, Hamilton JA, Hua N, Tripodis Y, Anderson AT, Howell GR, Kaufer D, Hall GF, Lu KP, Ransohoff RM, Cleveland RO, Kowall NW, Stein TD, Lamb BT, Huber BR, Moss WC, Friedman A, Stanton PK, McKee AC, Goldstein LE. Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model. Brain. 2018 02 01; 141(2):422-458.View Related Profiles.

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PMID: 29360998; PMCID: PMC5837414; DOI: 10.1093/brain/awx350;

Alosco ML, Sugarman MA, Besser LM, Tripodis Y, Martin B, Palmisano JN, Kowall NW, Au R, Mez J, DeCarli C, Stein TD, McKee AC, Killiany RJ, Stern RA. A Clinicopathological Investigation of White Matter Hyperintensities and Alzheimer's Disease Neuropathology. J Alzheimers Dis. 2018; 63(4):1347-1360.View Related Profiles.

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Stein, Thor
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PMID: 29843242; PMCID: PMC6081639; DOI: 10.3233/JAD-180017;

Tao Q, Zhu H, Chen X, Stern RA, Kowall N, Au R, Blusztajn JK, Qiu WQ. Pramlintide: The Effects of a Single Drug Injection on Blood Phosphatidylcholine Profile for Alzheimer's Disease. J Alzheimers Dis. 2018; 62(2):597-609.View Related Profiles.

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PMID: 29480193; PMCID: PMC5956916; DOI: 10.3233/JAD-170948;

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PMID: 29130578; PMCID: PMC5771400; DOI: 10.1111/acel.12679;

Friedman MJ, Huber BR, Brady CB, Ursano RJ, Benedek DM, Kowall NW, McKee AC. VA's National PTSD Brain Bank: a National Resource for Research. Curr Psychiatry Rep. 2017 Aug 25; 19(10):73.View Related Profiles.

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Huber, Bertrand
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PMID: 28840457

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Kowall, Neil
Stern, Robert
Cantu, Robert
Stein, Thor
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PMID: 28742910; PMCID: PMC5807097; DOI: 10.1001/jama.2017.8334;

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, et al. RarView Related Profiles.

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Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil
Yang, Qiong
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Choi, Seung Hoan
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PMID: 28714976; PMCID: PMC5669039; DOI: 10.1038/ng.3916;

Lee J, Hwang YJ, Kim Y, Lee MY, Hyeon SJ, Lee S, Kim DH, Jang SJ, Im H, Min SJ, Choo H, Pae AN, Kim DJ, Cho KS, Kowall NW, Ryu H. Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease. Acta Neuropathol. 2017 Nov; 134(5):729-748.View Related Profiles.

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PMID: 28593442

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McKee, Ann
Ryu, Hoon
Lee, Junghee
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Jung MK, Kim KY, Lee NY, Kang YS, Hwang YJ, Kim Y, Sung JJ, McKee A, Kowall N, Lee J, Ryu H. Expression of taurine transporter (TauT) is modulated by heat shock factor 1 (HSF1) in motor neurons of ALS. Mol Neurobiol. 2013 Apr; 47(2):699-710.View Related Profiles.

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Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.View Related Profiles.

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Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8.View Related Profiles.

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Lee J, Hong YK, Jeon GS, Hwang YJ, Kim KY, Seong KH, Jung MK, Picketts DJ, Kowall NW, Cho KS, Ryu H. ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease. Cell Death Differ. 2012 Jul; 19(7):1109-16.View Related Profiles.

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Chopra MP, Trevino KM, Kowall NW. Memantine for posttraumatic stress disorder in an older veteran. J Clin Psychopharmacol. 2011 Dec; 31(6):787-8. PMID: 22051925; DOI: 10.1097/JCP.0b013e31823657bf;

Lee J, Hwang YJ, Boo JH, Han D, Kwon OK, Todorova K, Kowall NW, Kim Y, Ryu H. Dysregulation of upstream binding factor-1 acetylation at K352 is linked to impaired ribosomal DNA transcription in Huntington's disease. Cell Death Differ. 2011 Nov; 18(11):1726-35.View Related Profiles.

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Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41.View Related Profiles.

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Ryu H, Jeon GS, Cashman NR, Kowall NW, Lee J. Differential expression of c-Ret in motor neurons versus non-neuronal cells is linked to the pathogenesis of ALS. Lab Invest. 2011 Mar; 91(3):342-52.View Related Profiles.

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Budson AE, Kowall NW (Editors). The Handbook of Alzheimer’s Disease and Other Dementias ISBN: 978-1-4051-6828-1. Wiley-Blackwell. 2011.
Butler D, Kowall N, Lawler E, Gaziano JM, Driver JA. Underuse of Diagnostic Codes for Specific Dementias in the VA New England Health Care System. J Am Geriatr Soc. 2011.

Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H. Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice. Acta Neuropathol. 2011 Apr; 121(4):487-98.View Related Profiles.

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van der Steen JT, Lane P, Kowall NW, Knol DL, Volicer L. Antibiotics and mortality in patients with lower respiratory infection and advanced dementia. J Am Med Dir Assoc. 2012 Feb; 13(2):156-61. PMID: 21450193; PMCID: PMC6290468; DOI: 10.1016/j.jamda.2010.07.001;

McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, Budson AE. TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2010 Sep; 69(9):918-29.View Related Profiles.

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PMID: 20720505; PMCID: PMC2951281; DOI: 10.1097/NEN.0b013e3181ee7d85;

Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Martin ER, Montine TJ, Goate AM, Blacker D, Tsuang DW, Beekly D, Cupples LA, Hakonarson H, Kukull W, Foroud TM, Haines J, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010 Dec; 67(12):1473-84.View Related Profiles.

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Carreras I, Yuruker S, Aytan N, Hossain L, Choi JK, Jenkins BG, Kowall NW, Dedeoglu A. Moderate exercise delays the motor performance decline in a transgenic model of ALS. Brain Res. 2010 Feb 8; 1313:192-201.View Related Profiles.

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Choi JK, Jenkins BG, Carreras I, Kaymakcalan S, Cormier K, Kowall NW, Dedeoglu A. Anti-inflammatory treatment in AD mice protects against neuronal pathology. Exp Neurol. 2010 Jun; 223(2):377-84.View Related Profiles.

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Lee J, Ryu H, Kowall NW. Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice. Biochem Biophys Res Commun. 2009 Sep 11; 387(1):202-6.View Related Profiles.

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Lee J, Ryu H, Kowall NW. Motor neuronal protection by L-arginine prolongs survival of mutant SOD1 (G93A) ALS mice. Biochem Biophys Res Commun. 2009 Jul 10; 384(4):524-9.View Related Profiles.

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Aydin C, Aytan N, Mahon MJ, Tawfeek HA, Kowall NW, Dedeoglu A, Bastepe M. Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha). Endocrinology. 2009 Aug; 150(8):3567-75.View Related Profiles.

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Lee J, Kannagi M, Ferrante RJ, Kowall NW, Ryu H. Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis. FASEB J. 2009 Jun; 23(6):1739-49.View Related Profiles.

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Yaar M, Arble BL, Stewart KB, Qureshi NH, Kowall NW, Gilchrest BA. p75NTR antagonistic cyclic peptide decreases the size of beta amyloid-induced brain inflammation. Cell Mol Neurobiol. 2008 Dec; 28(8):1027-31.View Related Profiles.

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Vlad SC, Miller DR, Kowall NW, Felson DT. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6; 70(19):1672-7.View Related Profiles.

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Harper DG, Stopa EG, Kuo-Leblanc V, McKee AC, Asayama K, Volicer L, Kowall N, Satlin A. Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia. Brain. 2008 Jun; 131(Pt 6):1609-17.View Related Profiles.

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McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res. 2008 May 1; 1207:225-36.View Related Profiles.

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Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ. Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. J Neurosci. 2007 Nov 21; 27(47):12908-15.View Related Profiles.

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Mellott TJ, Kowall NW, Lopez-Coviella I, Blusztajn JK. Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats. Brain Res. 2007 Jun 2; 1151:1-11.View Related Profiles.

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Lee J, Kosaras B, Aleyasin H, Han JA, Park DS, Ratan RR, Kowall NW, Ferrante RJ, Lee SW, Ryu H. Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. FASEB J. 2006 Nov; 20(13):2375-7.View Related Profiles.

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McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Wolf PA. Visual association pathology in preclinical Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jun; 65(6):621-30.View Related Profiles.

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Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet. 2006 May; 38(5):518-20.View Related Profiles.

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Klivenyi P, Siwek D, Gardian G, Yang L, Starkov A, Cleren C, Ferrante RJ, Kowall NW, Abeliovich A, Beal MF. Mice lacking alpha-synuclein are resistant to mitochondrial toxins. Neurobiol Dis. 2006 Mar; 21(3):541-8. PMID: 16298531

Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Exp Gerontol. 2004 Nov-Dec; 39(11-12):1641-9.View Related Profiles.

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Dedeoglu A, Choi JK, Cormier K, Kowall NW, Jenkins BG. Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile. Brain Res. 2004 Jun 25; 1012(1-2):60-5.View Related Profiles.

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Sheridan PL, Solomont J, Kowall N, Hausdorff JM. Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's disease. J Am Geriatr Soc. 2003 Nov; 51(11):1633-7. PMID: 14687395

Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B, Smith K, Kowall NW, Ratan RR, Luthi-Carter R, Hersch SM. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. J Neurosci. 2003 Oct 15; 23(28):9418-27.View Related Profiles.

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McKeon-O'Malley C, Siwek D, Lamoureux JA, Williams CL, Kowall NW. Prenatal choline deficiency decreases the cross-sectional area of cholinergic neurons in the medial septal nucleus. Brain Res. 2003 Jul 11; 977(2):278-83. PMID: 12834888

Albright CD, Siwek DF, Craciunescu CN, Mar MH, Kowall NW, Williams CL, Zeisel SH. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci. 2003 Apr; 6(2):129-34. PMID: 12722989

Dedeoglu A, Kubilus JK, Jeitner TM, Matson SA, Bogdanov M, Kowall NW, Matson WR, Cooper AJ, Ratan RR, Beal MF, Hersch SM, Ferrante RJ. Therapeutic effects of cystamine in a murine model of Huntington's disease. J Neurosci. 2002 Oct 15; 22(20):8942-50.View Related Profiles.

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Kiechle T, Dedeoglu A, Kubilus J, Kowall NW, Beal MF, Friedlander RM, Hersch SM, Ferrante RJ. Cytochrome C and caspase-9 expression in Huntington's disease. Neuromolecular Med. 2002; 1(3):183-95.View Related Profiles.

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Malin DH, Crothers MK, Lake JR, Goyarzu P, Plotner RE, Garcia SA, Spell SH, Tomsic BJ, Giordano T, Kowall NW. Hippocampal injections of amyloid beta-peptide 1-40 impair subsequent one-trial/day reward learning. Neurobiol Learn Mem. 2001 Sep; 76(2):125-37. PMID: 11502145

Andreassen OA, Ferrante RJ, Klivenyi P, Klein AM, Dedeoglu A, Albers DS, Kowall NW, Beal MF. Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Exp Neurol. 2001 Apr; 168(2):356-63.View Related Profiles.

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Montine TJ, Shinobu L, Montine KS, Roberts LJ, Kowall NW, Beal MF, Morrow JD. No difference in plasma or urinary F2-isoprostanes among patients with Huntington's disease or Alzheimer's disease and controls. Ann Neurol. 2000 Dec; 48(6):950. PMID: 11117557

Simon DK, Mayeux R, Marder K, Kowall NW, Beal MF, Johns DR. Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology. 2000 Feb 8; 54(3):703-9. PMID: 10680807

Kowall NW, Hantraye P, Brouillet E, Beal MF, McKee AC, Ferrante RJ. MPTP induces alpha-synuclein aggregation in the substantia nigra of baboons. Neuroreport. 2000 Jan 17; 11(1):211-3.View Related Profiles.

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Kowall, Neil

PMID: 10683860

Shefner JM, Reaume AG, Flood DG, Scott RW, Kowall NW, Ferrante RJ, Siwek DF, Upton-Rice M, Brown RH. Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy. Neurology. 1999 Oct 12; 53(6):1239-46. PMID: 10522879

Volicer L, Wells JM, McKee AC, Kowall NW. Enhanced inhibition of free radical-induced deoxyribose breakdown by Alzheimer brain homogenates. Neurosci Lett. 1999 Aug 6; 270(3):169-72.View Related Profiles.

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Kowall, Neil

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Hanlon EB, Itzkan I, Dasari RR, Feld MS, Ferrante RJ, McKee AC, Lathi D, Kowall NW. Near-infrared fluorescence spectroscopy detects Alzheimer's disease in vitro. Photochem Photobiol. 1999 Aug; 70(2):236-42.View Related Profiles.

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Kowall, Neil

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Kowall NW. Alzheimer disease 1999: a status report. Alzheimer Dis Assoc Disord. 1999 Apr-Jun; 13 Suppl 1:S11-6. PMID: 10369512

Klein AM, Kowall NW, Ferrante RJ. Neurotoxicity and oxidative damage of beta amyloid 1-42 versus beta amyloid 1-40 in the mouse cerebral cortex. Ann N Y Acad Sci. 1999; 893:314-20. PMID: 10672257

Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, Perry G. Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine. J Histochem Cytochem. 1998 Jun; 46(6):731-5. PMID: 9603784

McKee AC, Kowall NW, Schumacher JS, Beal MF. The neurotoxicity of amyloid beta protein in aged primates. Amyloid. 1998 Mar; 5(1):1-9.View Related Profiles.

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Kowall, Neil

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Kowall NW, Ferrante RJ. The Neuropathology of Huntington’s Disease. In: Neuropathology of Neurodegenerative diseases. Ed. W Markesberry. 1998.

Ferrante RJ, Browne SE, Shinobu LA, Bowling AC, Baik MJ, MacGarvey U, Kowall NW, Brown RH, Beal MF. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem. 1997 Nov; 69(5):2064-74. PMID: 9349552

Beal MF, Ferrante RJ, Browne SE, Matthews RT, Kowall NW, Brown RH. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol. 1997 Oct; 42(4):644-54. PMID: 9382477

Ferrante RJ, Shinobu LA, Schulz JB, Matthews RT, Thomas CE, Kowall NW, Gurney ME, Beal MF. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. Ann Neurol. 1997 Sep; 42(3):326-34. PMID: 9307254

Ferrante RJ, Gutekunst CA, Persichetti F, McNeil SM, Kowall NW, Gusella JF, MacDonald ME, Beal MF, Hersch SM. Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum. J Neurosci. 1997 May 1; 17(9):3052-63. PMID: 9096140

Ferrante RJ, Schulz JB, Kowall NW, Beal MF. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res. 1997 Apr 4; 753(1):157-62. PMID: 9125443

Ferrante RJ, Brouillet E, Hantraye P, Kowall NW, Bea, MF. Mitochondrial Dysfunction as a Model for Huntington's Disease Using the Electron Transport Chain Inhibitor, 3-Nitropropionic Acid. In: Neurodegenerative Diseases: Mitochondria and Free Radicals in Pathogenesis. eds. M. Flint. Beal, Ivan BodisWollner, and Neil Howell. 1997; 229-244.

Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N. Oxidative damage in Alzheimer's. Nature. 1996 Jul 11; 382(6587):120-1. PMID: 8700201

Speliotes EK, Caday CG, Do T, Weise J, Kowall NW, Finklestein SP. Increased expression of basic fibroblast growth factor (bFGF) following focal cerebral infarction in the rat. Brain Res Mol Brain Res. 1996 Jul; 39(1-2):31-42. PMID: 8804711

Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH, Scott RW, Snider WD. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet. 1996 May; 13(1):43-7. PMID: 8673102

De Gasperi R, Angel M, Sosa G, Patarca R, Battistini S, Lamoreux MR, Raghavan S, Kowall NW, Smith KH, Fletcher MA, Kolodny EH. Intrathecal synthesis of anti-sulfatide IgG is associated with peripheral nerve disease in acquired immunodeficiency syndrome. AIDS Res Hum Retroviruses. 1996 Feb 10; 12(3):205-11. PMID: 8835198

Speliotes EK, Kowall NW, Shanti BF, Kosofsky B, Finklestein SP, Leifer D. Myocyte-specific enhancer binding factor 2C expression in gerbil brain following global cerebral ischemia. Neuroscience. 1996 Jan; 70(1):67-77. PMID: 8848137

Farrer LA, Abraham CR, Volicer L, Foley EJ, Kowall NW, McKee AC, Wells JM. Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Exp Neurol. 1995 Dec; 136(2):162-70.View Related Profiles.

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Abraham, Carmela
Farrer, Lindsay
Kowall, Neil

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Schulz JB, Matthews RT, Jenkins BG, Ferrante RJ, Siwek D, Henshaw DR, Cipolloni PB, Mecocci P, Kowall NW, Rosen BR, et al. Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo. J Neurosci. 1995 Dec; 15(12):8419-29. PMID: 8613773

Beal MF, Ferrante RJ, Henshaw R, Matthews RT, Chan PH, Kowall NW, Epstein CJ, Schulz JB. 3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice. J Neurochem. 1995 Aug; 65(2):919-22. PMID: 7616254

Brouillet E, Hantraye P, Ferrante RJ, Dolan R, Leroy-Willig A, Kowall NW, Beal MF. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15):7105-9. PMID: 7624378; PMCID: PMC41480

Matsumoto K, Lo EH, Pierce AR, Wei H, Garrido L, Kowall NW. Role of vasogenic edema and tissue cavitation in ischemic evolution on diffusion-weighted imaging: comparison with multiparameter MR and immunohistochemistry. AJNR Am J Neuroradiol. 1995 May; 16(5):1107-15. PMID: 7639135

Schulz JB, Henshaw DR, Siwek D, Jenkins BG, Ferrante RJ, Cipolloni PB, Kowall NW, Rosen BR, Beal MF. Involvement of free radicals in excitotoxicity in vivo. J Neurochem. 1995 May; 64(5):2239-47. PMID: 7536809

Kowall NW. How tight is the connection between synapse loss and clinical dementia? Neurobiol Aging. 1995; 16:300-302.

Schwagerl AL, Mohan PS, Cataldo AM, Vonsattel JP, Kowall NW, Nixon RA. Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease. J Neurochem. 1995 Jan; 64(1):443-6. PMID: 7798944

Leifer D, Golden J, Kowall NW. Myocyte-specific enhancer binding factor 2C expression in human brain development. Neuroscience. 1994 Dec; 63(4):1067-79. PMID: 7700509

Schulz JB, Henshaw DR, Jenkins BG, Ferrante RJ, Kowall NW, Rosen BR, Beal MF. 3-Acetylpyridine produces age-dependent excitotoxic lesions in rat striatum. J Cereb Blood Flow Metab. 1994 Nov; 14(6):1024-9. PMID: 7929644

Boviatsis EJ, Scharf JM, Chase M, Harrington K, Kowall NW, Breakefield XO, Chiocca EA. Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase. Gene Ther. 1994 Sep; 1(5):323-31. PMID: 7584098

Volicer L, Hurley AC, Lathi DC, Kowall NW. Measurement of severity in advanced Alzheimer's disease. J Gerontol. 1994 Sep; 49(5):M223-6. PMID: 8056941

Wei MX, Tamiya T, Chase M, Boviatsis EJ, Chang TK, Kowall NW, Hochberg FH, Waxman DJ, Breakefield XO, Chiocca EA. Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene. Hum Gene Ther. 1994 Aug; 5(8):969-78.View Related Profiles.

Waxman, David
Kowall, Neil

PMID: 7948146

Storey E, Cipolloni PB, Ferrante RJ, Kowall NW, Beal MF. Movement disorder following excitotoxin lesions in primates. Neuroreport. 1994 Jun 2; 5(10):1259-61. PMID: 7919178

Rosen DR, Bowling AC, Patterson D, Usdin TB, Sapp P, Mezey E, McKenna-Yasek D, O'Regan J, Rahmani Z, Ferrante RJ, et al. A frequent ala 4 to val superoxide dismutase-1 mutation is associated with a rapidly progressive familial amyotrophic lateral sclerosis. Hum Mol Genet. 1994 Jun; 3(6):981-7. PMID: 7951249

Henshaw R, Jenkins BG, Schulz JB, Ferrante RJ, Kowall NW, Rosen BR, Beal MF. Malonate produces striatal lesions by indirect NMDA receptor activation. Brain Res. 1994 May 30; 647(1):161-6. PMID: 8069700

Koketsu N, Berlove DJ, Moskowitz MA, Kowall NW, Caday CG, Finklestein SP. Pretreatment with intraventricular basic fibroblast growth factor decreases infarct size following focal cerebral ischemia in rats. Ann Neurol. 1994 Apr; 35(4):451-7. PMID: 8154872

Kowall NW. Beta amyloid neurotoxicity and neuronal degeneration in Alzheimer's disease. Neurobiol Aging. 1994 Mar-Apr; 15(2):257-8. PMID: 7838305

Giordano T, Pan JB, Monteggia LM, Holzman TF, Snyder SW, Krafft G, Ghanbari H, Kowall NW. Similarities between beta amyloid peptides 1-40 and 40-1: effects on aggregation, toxicity in vitro, and injection in young and aged rats. Exp Neurol. 1994 Feb; 125(2):175-82. PMID: 8313936

Boviatsis EJ, Chase M, Wei MX, Tamiya T, Hurford RK, Kowall NW, Tepper RI, Breakefield XO, Chiocca EA. Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. Hum Gene Ther. 1994 Feb; 5(2):183-91. PMID: 8186298

Lo EH, Pan Y, Matsumoto K, Kowall NW. Blood-brain barrier disruption in experimental focal ischemia: comparison between in vivo MRI and immunocytochemistry. Magn Reson Imaging. 1994; 12(3):403-11. PMID: 8007769

Ferrante RJ, Beal MF, Kowall NW. Mechanisms of neuronal degeneration in Huntington's disease. In: G Percheron JS McKenzie and J. Feger ed. The Basal Ganglia IV: New Ideas and Data on Structure and Function. Plenum Press. New York. 1994; 149-161.
Lathi DC, Kemper T, Rosalis R, Mahasaen C, Kowall NW . A quantitative regional analysis of vascular amyloidosis in Alzheimer's disease. Proc VII Intl Symp on Amyloidosis. 1994.
Ferrante RJ, Kowall NW, Richardson EP Jr. Neuronal plasticity: a potential role in spiny striatal neuron degeneration in Huntington's disease. In: K Fuxe, LF Agnati, B Bjelke, D Ottoson ed. Trophic Regulation of the Basal Ganglia - focus on dopamine neurons. 1994; 465-477.

Leifer D, Kowall NW. Immunohistochemical patterns of selective cellular vulnerability in human cerebral ischemia. J Neurol Sci. 1993 Nov; 119(2):217-28. PMID: 8277338

Beal MF, Brouillet E, Jenkins BG, Ferrante RJ, Kowall NW, Miller JM, Storey E, Srivastava R, Rosen BR, Hyman BT. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci. 1993 Oct; 13(10):4181-92. PMID: 7692009

Nihei K, Kowall NW. Involvement of NPY-immunoreactive neurons in the cerebral cortex of amyotrophic lateral sclerosis patients. Neurosci Lett. 1993 Sep 3; 159(1-2):67-70. PMID: 8264981

Kowall NW, Quigley BJ, Krause JE, Lu F, Kosofsky BE, Ferrante RJ. Substance P and substance P receptor histochemistry in human neurodegenerative diseases. Regul Pept. 1993 Jul 2; 46(1-2):174-85. PMID: 7692486

Markesbery WR, Wang HZ, Kowall NW, Kosik KS, McKee AC. Morphometric image analysis of neuropil threads in Alzheimer's disease. Neurobiol Aging. 1993 Jul-Aug; 14(4):303-7.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 8367011

Ferrante RJ, Kowall NW, Cipolloni PB, Storey E, Beal MF. Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization. Exp Neurol. 1993 Jan; 119(1):46-71. PMID: 8432351

Kowall NW, McKee AC. The histopathology of neuronal degeneration and plasticity in Alzheimer disease. Adv Neurol. 1993; 59:5-33.View Related Profiles.

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Kowall, Neil

PMID: 8420123

Nihei K, McKee AC, Kowall NW. Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis patients. Acta Neuropathol. 1993; 86(1):55-64.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 8396837

Brouillet E, Jenkins BG, Hyman BT, Ferrante RJ, Kowall NW, Srivastava R, Roy DS, Rosen BR, Beal MF. Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid. J Neurochem. 1993 Jan; 60(1):356-9. PMID: 8417157

Kowall NW , McKee AC. The histopathology of neuronal degeneration and plasticity in Alzheimer's disease. In: Neural Regeneration, ed. F.J. Seil Advances in Neurology. Raven Press. New York,NY. 1993; 59:5-33.

Storey E, Kowall NW, Finn SF, Mazurek MF, Beal MF. The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex. Ann Neurol. 1992 Oct; 32(4):526-34. PMID: 1280937

Kowall NW, McKee AC, Yankner BA, Beal MF. In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment. Neurobiol Aging. 1992 Sep-Oct; 13(5):537-42.View Related Profiles.

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Kowall, Neil

PMID: 1461341

Yokota M, Peterson JW, Kaoutzanis M, Kowall NW. Immunohistochemical distribution of protein kinase C isozymes is differentially altered in ischemic gerbil hippocampus. Brain Res. 1992 Jul 31; 587(1):123-9. PMID: 1525642

deVeber GA, Schwarting GA, Kolodny EH, Kowall NW. Fabry disease: immunocytochemical characterization of neuronal involvement. Ann Neurol. 1992 Apr; 31(4):409-15. PMID: 1375013

Leifer D, Kowall NW. Thy-1 in hippocampus: normal anatomy and neuritic growth in Alzheimer's disease. J Neuropathol Exp Neurol. 1992 Mar; 51(2):133-41. PMID: 1347079

Nihei K, Kowall NW. Neurofilament and neural cell adhesion molecule immunocytochemistry of Huntington's disease striatum. Ann Neurol. 1992 Jan; 31(1):59-63. PMID: 1531909

Kowall NW. Primitive Reflexes. In: Disorders of Movement in Psychiatry and Neurology, ed. Joseph AB and Young RR. Blackwell. London. 1992; 699-703.
Lee JM, Weinstein DA, Kowall NW, Beal MF . Inability of ß-amyloid (ß(25-35)) to bind to central nervous system neurokinin 1 receptors. Drug Dev Res. 1992; 27:441-444.

Wang LN, Kowall NW, Richardson EP. Phosphorylated neurofilament epitopes in the achromasic neurons of corticonigral degeneration. Chin Med J (Engl). 1991 Dec; 104(12):1011-7. PMID: 1782810

Ferrante RJ, Kowall NW, Richardson EP. Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry. J Neurosci. 1991 Dec; 11(12):3877-87. PMID: 1836019

Kowall NW, Beal MF, Busciglio J, Duffy LK, Yankner BA. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):7247-51. PMID: 1714596; PMCID: PMC52271

McKee AC, Kosik KS, Kowall NW. Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol. 1991 Aug; 30(2):156-65.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 1910274

Uemura Y, Kowall NW, Moskowitz MA. Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex. Brain Res. 1991 Jun 21; 552(1):99-105. PMID: 1913186

Beal MF, Ferrante RJ, Swartz KJ, Kowall NW. Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci. 1991 Jun; 11(6):1649-59. PMID: 1710657

Leifer D, Cole DG, Kowall NW. Neuropathologic asymmetries in the brain of a patient with a unilateral status epilepticus. J Neurol Sci. 1991 Jun; 103(2):127-35. PMID: 1715386

Uemura Y, Kowall NW, Beal MF. Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus. Brain Res. 1991 Mar 1; 542(2):343-7. PMID: 1827611

Kowall NW, Beal MF. Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Ann Neurol. 1991 Feb; 29(2):162-7. PMID: 1672808

Quigley BJ, Kowall NW. Substance P-like immunoreactive neurons are depleted in Alzheimer's disease cerebral cortex. Neuroscience. 1991; 41(1):41-60. PMID: 1711654

Beal MF, Swartz KJ, Finn SF, Mazurek MF, Kowall NW. Neurochemical characterization of excitotoxin lesions in the cerebral cortex. J Neurosci. 1991 Jan; 11(1):147-58. PMID: 1670782

Kowall NW , Kosik KS. Histochemical observations on neuronal degeneration, cytoskeletal reorganization and phosphorylation in Alzheimer's disease. Proceedings of the XIth Intl Congress of Neuropathology. 1991; 105-109.

Sangruchi T, Kowall NW. NADPH diaphorase histochemistry of the human hypothalamus. Neuroscience. 1991; 40(3):713-24. PMID: 2062439

Uemura Y, Kowall NW, Beal MF. Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum. Ann Neurol. 1990 Jun; 27(6):620-5. PMID: 1972876

McKee AC, Levine DN, Kowall NW, Richardson EP. Peduncular hallucinosis associated with isolated infarction of the substantia nigra pars reticulata. Ann Neurol. 1990 May; 27(5):500-4.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 2360791

Thulborn KR, Sorensen AG, Kowall NW, McKee A, Lai A, McKinstry RC, Moore J, Rosen BR, Brady TJ. The role of ferritin and hemosiderin in the MR appearance of cerebral hemorrhage: a histopathologic biochemical study in rats. AJR Am J Roentgenol. 1990 May; 154(5):1053-9. PMID: 2108542

Thulborn KR, Sorensen AG, Kowall NW, McKee A, Lai A, McKinstry RC, Moore J, Rosen BR, Brady TJ. The role of ferritin and hemosiderin in the MR appearance of cerebral hemorrhage: a histopathologic biochemical study in rats. AJNR Am J Neuroradiol. 1990 Mar-Apr; 11(2):291-7. PMID: 1690500

Cudkowicz M, Kowall NW. Degeneration of pyramidal projection neurons in Huntington's disease cortex. Ann Neurol. 1990 Feb; 27(2):200-4. PMID: 2138444

McKee AC, Kosik KS, Kennedy MB, Kowall NW. Hippocampal neurons predisposed to neurofibrillary tangle formation are enriched in type II calcium/calmodulin-dependent protein kinase. J Neuropathol Exp Neurol. 1990 Jan; 49(1):49-63.View Related Profiles.

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Kowall, Neil

PMID: 2153760

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ. Homocysteic acid lesions in rat striatum spare somatostatin-neuropeptide Y (NADPH-diaphorase) neurons. Neurosci Lett. 1990 Jan 1; 108(1-2):36-42. PMID: 1689475

Kostyk SK, Kowall NW, Hauser SL. Substance P immunoreactive astrocytes are present in multiple sclerosis plaques. Brain Res. 1989 Dec 18; 504(2):284-8. PMID: 2480834

Kelley M, Kowall N. Corticotropin-releasing factor immunoreactive neurons persist throughout the brain in Alzheimer's disease. Brain Res. 1989 Nov 6; 501(2):392-6. PMID: 2819447

McKee AC, Kowall NW, Kosik KS. Microtubular reorganization and dendritic growth response in Alzheimer's disease. Ann Neurol. 1989 Nov; 26(5):652-9.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 2817839

Kowall NW, Beal MF. Galanin-like immunoreactivity is present in human substantia innominata and in senile plaques in Alzheimer's disease. Neurosci Lett. 1989 Mar 13; 98(1):118-23. PMID: 2469045

Martin JB, Beal MF, Kowall NW, Mazurek MF. Alterations of neuropeptide Y in neurological disorders. In: Neuropeptide Y, Karolinska Institute Nobel Conference Series, ed. Mutt V, Hokflet T, Fuxe K, and Lundberg JM. Raven Press. New York,NY. 1989; 313-320.

Kowall NW, Pendlebury WW, Kessler JB, Perl DP, Beal MF. Aluminum-induced neurofibrillary degeneration affects a subset of neurons in rabbit cerebral cortex, basal forebrain and upper brainstem. Neuroscience. 1989; 29(2):329-37. PMID: 2725861

Beal MF, Mazurek MF, Ellison DW, Kowall NW, Solomon PR, Pendlebury WW. Neurochemical characteristics of aluminum-induced neurofibrillary degeneration in rabbits. Neuroscience. 1989; 29(2):339-46. PMID: 2566953

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse. 1989; 3(1):38-47. PMID: 2563916

Kosik KS, Kowall NW, McKee A. Along the way to a neurofibrillary tangle: a look at the structure of tau. Ann Med. 1989; 21(2):109-12. PMID: 2504256

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Systemic approaches to modifying quinolinic acid striatal lesions in rats. J Neurosci. 1988 Oct; 8(10):3901-8. PMID: 2461437

Kowall NW, Mueller MP. Morphology and distribution of nicotinamide adenine dinucleotide phosphate (reduced form) diaphorase reactive neurons in human brainstem. Neuroscience. 1988 Aug; 26(2):645-54. PMID: 3173692

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Response:Model of Huntington's disease. Science. 1988 Jul 22; 241(4864):475. PMID: 17792612

Kowall NW, Beal MF. Cortical somatostatin, neuropeptide Y, and NADPH diaphorase neurons: normal anatomy and alterations in Alzheimer's disease. Ann Neurol. 1988 Feb; 23(2):105-14. PMID: 2897822

Pendlebury WW, Beal MF, Kowall NW, Solomon PR. Neuropathologic, neurochemical and immunocytochemical characteristics of aluminum-induced neurofilamentous degeneration. Neurotoxicology. 1988; 9(3):503-10. PMID: 3200512

Martin JB, Beal MF, Mazurek MF, Kowall NW, Growdon JH. Some observations on the significance of neurotransmitter changes in Alzheimer Disease. In: Aging and the Brain, ed. Terry RD. Raven. New York,NY. 1988; 32:129-148.
Kowall NW, Sobel RA. Case Records of the Massachusetts General Hospital (Case 7-88). NEJM. 1988; 318:427-440.
Kowall NW, Mueller MG . Topography of NADPH diaphorase neurons in human brainstem. Neuroscience. 1988; 26:645-654.

Kowall NW, Kosik KS. Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease. Ann Neurol. 1987 Nov; 22(5):639-43. PMID: 3122646

Ferrante RJ, Kowall NW. Tyrosine hydroxylase-like immunoreactivity is distributed in the matrix compartment of normal human and Huntington's disease striatum. Brain Res. 1987 Jul 21; 416(1):141-6. PMID: 2887244

Ellison DW, Kowall NW, Martin JB. Subset of neurons characterized by the presence of NADPH-diaphorase in human substantia innominata. J Comp Neurol. 1987 Jun 8; 260(2):233-45. PMID: 3611405

Ferrante RJ, Beal MF, Kowall NW, Richardson EP, Martin JB. Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease. Brain Res. 1987 May 12; 411(1):162-6. PMID: 2955849

Kowall NW, Ferrante RJ, Beal MF, Richardson EP, Sofroniew MV, Cuello AC, Martin JB. Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: a combined immunocytochemical and enzyme histochemical study. Neuroscience. 1987 Mar; 20(3):817-28. PMID: 2885780

Beal MF, Kowall NW, Mazurek MF. Neuropeptides in Alzheimer's disease. J Neural Transm Suppl. 1987; 24:163-74. PMID: 2445913

Kowall NW, Ferrante RJ, Martin JB. Neuropathology of Huntington's disease-reply. Trends in Neurosciences. 1987; 10:404-406.

Pendlebury WW, Beal MF, Kowall NW, Solomon PR. Results of immunocytochemical, neurochemical, and behavioral studies in aluminum-induced neurofilamentous degeneration. J Neural Transm Suppl. 1987; 24:213-7. PMID: 3479524

Kosik KS, Rogers J, Kowall NW. Senile plaques are located between apical dendritic clusters. J Neuropathol Exp Neurol. 1987 Jan; 46(1):1-11. PMID: 3794758

Kowall NW, Ferrante RJ, Martin JB. Patterns of cell loss in Huntington's disease. Trends in Neurosciences. 1987; 10:24-29.

Ferrante RJ, Kowall NW, Beal MF, Martin JB, Bird ED, Richardson EP. Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease. J Neuropathol Exp Neurol. 1987 Jan; 46(1):12-27. PMID: 2947977

Ferrante RJ, Kowall NW, Richardson EP, Bird ED, Martin JB. Topography of enkephalin, substance P and acetylcholinesterase staining in Huntington's disease striatum. Neurosci Lett. 1986 Nov 21; 71(3):283-8. PMID: 2432445

Haber SN, Kowall NW, Vonsattel JP, Bird ED, Richardson EP. Gilles de la Tourette's syndrome. A postmortem neuropathological and immunohistochemical study. J Neurol Sci. 1986 Sep; 75(2):225-41. PMID: 2428943

Groenewegen HJ, Ahlenius S, Haber SN, Kowall NW, Nauta WJ. Cytoarchitecture, fiber connections, and some histochemical aspects of the interpeduncular nucleus in the rat. J Comp Neurol. 1986 Jul 1; 249(1):65-102. PMID: 2426312

Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, Martin JB. Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature. 1986 May 8-14; 321(6066):168-71. PMID: 2422561

Beal MF, Uhl G, Mazurek MF, Kowall N, Martin JB. Somatostatin: alterations in the central nervous system in neurological diseases. Res Publ Assoc Res Nerv Ment Dis. 1986; 64:215-57. PMID: 2873636

Ferrante RJ, Kowall NW, Beal MF, Richardson EP, Bird ED, Martin JB. Selective sparing of a class of striatal neurons in Huntington's disease. Science. 1985 Nov 1; 230(4725):561-3. PMID: 2931802

Kowall NW, Beal MF, Ferrante RJ, Martin JB. Topography of nicotinamide adenine dinucleotide phosphate-diaphorase staining neurons in rat striatum. Neurosci Lett. 1985 Aug 16; 59(1):61-6. PMID: 2931630

Kowall N, Stansbury R, Charman H, Gardner M. A current look at feline lymphoma. Vet Clin North Am. 1971 May; 1(2):355-65. PMID: 4347118

Martin JB, Kowall NW, Ferrante RJ. Striatal degeneration and neuronal sparing in Huntington's disease, Butterworths.
Martin JB, Ferrante RJ, Kowall NW. Individual cell types as targets of neural disease processes in Huntington's disease. In: Molecular Biology of the Human Brain, ed. Jones EG . UCLA symposium. Alan R. Liss. New York,NY. 72.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 269 publications over 40 distinct years, with a maximum of 16 publications in 1994 and 2013

Bar chart showing 269 publications over 40 distinct years, with a maximum of 16 publications in 1994 and 2013

Year	Publications
1985	2
1986	5
1987	11
1988	8
1989	9
1990	7
1991	13
1992	8
1993	10
1994	16
1995	8
1996	5
1997	6
1998	3
1999	5
2000	3
2001	2
2002	2
2003	4
2004	2
2005	1
2006	3
2007	2
2008	5
2009	6
2010	4
2011	6
2012	9
2013	16
2014	8
2015	5
2016	4
2017	12
2018	11
2019	10
2020	10
2021	10
2022	7
2023	8
2024	3

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