Keywords
Last Name

Kazem M. Azadzoi, MD

TitleResearch Professor
InstitutionBoston University School of Medicine
DepartmentUrology
Address72 E. Concord St Robinson (B)
Boston MA 02118
Phone(617) 638-8451
Other Positions
TitleResearch Professor
InstitutionBoston University School of Medicine
DepartmentPathology & Laboratory Medicine

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Zhao Z, Azadzoi KM, Choi HP, Jing R, Lu X, Li C, Wang F, Lu J, Yang JH. LC-MS/MS Analysis Unravels Deep Oxidation of Manganese Superoxide Dismutase in Kidney Cancer. Int J Mol Sci. 2017 Feb 04; 18(2). PMID: 28165386.
    View in: PubMed
  2. Li C, Wang D, Lv X, Jing R, Bi B, Chen X, Guo J, Wang F, Sun S, Azadzoi KM, Yang JH. Yersinia pestis acetyltransferase-mediated dual acetylation at the serine and lysine residues enhances the auto-ubiquitination of ubiquitin ligase MARCH8 in human cells. Cell Cycle. 2017 Jan 19; 1-11. PMID: 28103160.
    View in: PubMed
  3. Zhao Z, Azad R, Yang JH, Siroky MB, Azadzoi KM. Progressive changes in detrusor function and micturition patterns with chroinc bladder ischemia. Investig Clin Urol. 2016 Jul; 57(4):249-59. PMID: 27437534.
    View in: PubMed
  4. Guo J, Wang X, Lü X, Jing R, Li J, Li C, Wang D, Bi B, Chen X, Wang F, Sun S, Gong J, Azadzoi KM, Yang JH. Unraveling molecular effects of ADAR1 overexpression in HEK293T cells by label-free quantitative proteomics. Cell Cycle. 2016 Jun 17; 15(12):1591-601. PMID: 27104882.
    View in: PubMed
  5. Wang W, Wang WH, Azadzoi KM, Su N, Dai P, Sun J, Wang Q, Liang P, Zhang W, Lei X, Yan Z, Yang JH. Activation of innate antiviral immune response via double-stranded RNA-dependent RLR receptor-mediated necroptosis. Sci Rep. 2016 Mar 03; 6:22550. PMID: 26935990.
    View in: PubMed
  6. Wang W, Wang WH, Azadzoi KM, Dai P, Wang Q, Sun JB, Zhang WT, Shu Y, Yang JH, Yan Z. Alu RNA accumulation in hyperglycemia augments oxidative stress and impairs eNOS and SOD2 expression in endothelial cells. Mol Cell Endocrinol. 2016 May 05; 426:91-100. PMID: 26891959.
    View in: PubMed
  7. Dai P, Wang Q, Wang W, Jing R, Wang W, Wang F, Azadzoi KM, Yang JH, Yan Z. Unraveling Molecular Differences of Gastric Cancer by Label-Free Quantitative Proteomics Analysis. Int J Mol Sci. 2016 Jan 21; 17(1). PMID: 26805816.
    View in: PubMed
  8. Thurmond P, Yang JH, Azadzoi KM. LUTS IN PELVIC ISCHEMIA: A NEW CONCEPT IN VOIDING DYSFUNCTION. Am J Physiol Renal Physiol. 2016 Jan 20; ajprenal.00333.2015. PMID: 26792064.
    View in: PubMed
  9. Su N, Choi HP, Wang F, Su H, Fei Z, Yang JH, Azadzoi KM. Quantitative Proteomic Analysis of Differentially Expressed Proteins and Downstream Signaling Pathways in Chronic Bladder Ischemia. J Urol. 2016 Feb; 195(2):515-23. PMID: 26417643.
    View in: PubMed
  10. Thurmond P, Yang JH, Li Y, Lerner LB, Azadzoi KM. Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia. Korean J Urol. 2015 Mar; 56(3):187-96. PMID: 25763122.
    View in: PubMed
  11. Rai A, Nimeh T, Sood A, Thirumavalavan N, Thurmond PE, Azadzoi KM, Lerner LB. Could nocturia be an indicator of an undiagnosed sleep disorder in male veterans? Urology. 2015 Mar; 85(3):641-7. PMID: 25733279.
    View in: PubMed
  12. Lei X, Liu C, Azadzoi K, Li C, Lu F, Xiang A, Sun J, Guo Y, Zhao Q, Yan Z, Yang J. A novel IgM-H-ficolin complement pathway to attack allogenic cancer cells in vitro. Sci Rep. 2015; 5:7824. PMID: 25592840.
    View in: PubMed
  13. Witthaus MW, Nipa F, Yang JH, Li Y, Lerner LB, Azadzoi KM. Bladder oxidative stress in sleep apnea contributes to detrusor instability and nocturia. J Urol. 2015 May; 193(5):1692-9. PMID: 25463994.
    View in: PubMed
  14. Zhang Q, Siroky M, Yang JH, Zhao Z, Azadzoi K. Effects of ischemia and oxidative stress on bladder purinoceptors expression. Urology. 2014 Nov; 84(5):1249.e1-7. PMID: 25219364.
    View in: PubMed
  15. Liu D, Liu C, Li J, Azadzoi K, Yang Y, Fei Z, Dou K, Kowall NW, Choi HP, Vieira F, Yang JH. Proteomic analysis reveals differentially regulated protein acetylation in human amyotrophic lateral sclerosis spinal cord. PLoS One. 2013; 8(12):e80779. PMID: 24312501.
    View in: PubMed
  16. Azadzoi KM and Siroky MB. Mechanism of lower urinary tract symptoms in pelvic ischemia. J Biochem & Pharmacol Res. 2013; 1(1):64-74.
  17. Azadzoi KM, Yang J and Siroky MB. Neural regulation of sexual function in men. World J Clin Urol. 2013; 2(3)(24):32-41.
  18. Azadzoi KM, Chen BG, Radisavljevic ZM, Siroky MB. Molecular reactions and ultrastructural damage in the chronically ischemic bladder. J Urol. 2011 Nov; 186(5):2115-22. PMID: 21944111.
    View in: PubMed
  19. Azadzoi KM, Yalla SV, Siroky MB. Human bladder smooth muscle cell damage in disturbed oxygen tension. Urology. 2011 Oct; 78(4):967.e9-15. PMID: 21872910.
    View in: PubMed
  20. Zhang Q, Radisavljevic ZM, Siroky MB, Azadzoi KM. Dietary antioxidants improve arteriogenic erectile dysfunction. Int J Androl. 2011 Jun; 34(3):225-35. PMID: 20584092.
    View in: PubMed
  21. Azadzoi KM, Siroky MB. Neurologic factors in female sexual function and dysfunction. Korean J Urol. 2010 Jul; 51(7):443-9. PMID: 20664775.
    View in: PubMed
  22. Azadzoi KM, Radisavljevic ZM, Golabek T, Yalla SV, Siroky MB. Oxidative modification of mitochondrial integrity and nerve fiber density in the ischemic overactive bladder. J Urol. 2010 Jan; 183(1):362-9. PMID: 19914644.
    View in: PubMed
  23. Azadzoi KM, Golabek T, Radisavljevic ZM, Yalla SV, Siroky MB. Oxidative stress and neurodegeneration in penile ischaemia. BJU Int. 2010 Feb; 105(3):404-10. PMID: 19549113.
    View in: PubMed
  24. Azadzoi KM, Radisavljevic ZM, Siroky MB. Effects of ischemia on tachykinin-containing nerves and neurokinin receptors in the rabbit bladder. Urology. 2008 May; 71(5):979-83. PMID: 18314167.
    View in: PubMed
  25. Azadzoi KM. Editorial comment on: Immunohistochemical distribution of cyclic GMP-dependent protein kinase-1 in human prostate tissue. Eur Urol. 2007 Aug; 52(2):501-2. PMID: 17329017.
    View in: PubMed
  26. Azadzoi KM, Yalla SV, Siroky MB. Oxidative stress and neurodegeneration in the ischemic overactive bladder. J Urol. 2007 Aug; 178(2):710-5. PMID: 17574610.
    View in: PubMed
  27. Azadzoi KM. Vasculogenic erectile dysfunction: beyond the haemodynamic changes. BJU Int. 2006 Jan; 97(1):11-6. PMID: 16336320.
    View in: PubMed
  28. Azadzoi KM, Schulman RN, Aviram M, Siroky MB. Oxidative stress in arteriogenic erectile dysfunction: prophylactic role of antioxidants. J Urol. 2005 Jul; 174(1):386-93. PMID: 15947695.
    View in: PubMed
  29. Wang T, Soker S, Atala A, Siroky MB, Azadzoi KM. Alterations in angiogenic growth factors and neuronal nitric oxide synthase expression in chronic cavernosal ischemia. Int J Impot Res. 2004 Oct; 16(5):403-11. PMID: 14999219.
    View in: PubMed
  30. Azadzoi KM, Master TA, Siroky MB. Effect of chronic ischemia on constitutive and inducible nitric oxide synthase expression in erectile tissue. J Androl. 2004 May-Jun; 25(3):382-8. PMID: 15064316.
    View in: PubMed
  31. Azadzoi KM, Heim VK, Tarcan T, Siroky MB. Alteration of urothelial-mediated tone in the ischemic bladder: role of eicosanoids. Neurourol Urodyn. 2004; 23(3):258-64. PMID: 15098224.
    View in: PubMed
  32. Azadzoi KM, Babayan RK, Kozlowski R, Siroky MB. Chronic ischemia increases prostatic smooth muscle contraction in the rabbit. J Urol. 2003 Aug; 170(2 Pt 1):659-63. PMID: 12853851.
    View in: PubMed
  33. Siroky MB, Azadzoi KM. Vasculogenic erectile dysfunction: newer therapeutic strategies. J Urol. 2003 Aug; 170(2 Pt 2):S24-9; discussion S29-30. PMID: 12853769.
    View in: PubMed
  34. Azadzoi KM, Shinde VM, Tarcan T, Kozlowski R, Siroky MB. Increased leukotriene and prostaglandin release, and overactivity in the chronically ischemic bladder. J Urol. 2003 May; 169(5):1885-91. PMID: 12686867.
    View in: PubMed
  35. Azadzoi KM. Effect of chronic ischemia on bladder structure and function. Adv Exp Med Biol. 2003; 539(Pt A):271-80. PMID: 15088910.
    View in: PubMed
  36. Kozlowski R, Siroky MB, Krane RJ, Azadzoi KM. Regulation of blood flow and microcirculation resistance in rabbit bladder. J Urol. 2002 Oct; 168(4 Pt 1):1608-14. PMID: 12352466.
    View in: PubMed
  37. Kershen RT, Azadzoi KM, Siroky MB. Blood flow, pressure and compliance in the male human bladder. J Urol. 2002 Jul; 168(1):121-5. PMID: 12050504.
    View in: PubMed
  38. Kim NN, Dhir V, Azadzoi KM, Traish AM, Flaherty E, Goldstein I. Pilot study of the endothelin-A receptor selective antagonist BMS-193884 for the treatment of erectile dysfunction. J Androl. 2002 Jan-Feb; 23(1):76-83. PMID: 11780926.
    View in: PubMed
  39. Park K, Ahn K, Lee S, Ryu S, Park Y, Azadzoi KM. Decreased circulating levels of estrogen alter vaginal and clitoral blood flow and structure in the rabbit. Int J Impot Res. 2001 Apr; 13(2):116-24. PMID: 11426351.
    View in: PubMed
  40. Kozlowski R, Kershen RT, Siroky MB, Krane RJ, Azadzoi KM. Chronic ischemia alters prostate structure and reactivity in rabbits. J Urol. 2001 Mar; 165(3):1019-26. PMID: 11176533.
    View in: PubMed
  41. Tarcan T, Siroky MB, Park K, Goldstein I, Azadzoi KM. Systemic administration of apomorphine improves the hemodynamic mechanism of clitoral and vaginal engorgement in the rabbit. Int J Impot Res. 2000 Aug; 12(4):235-40. PMID: 11079365.
    View in: PubMed
  42. Park K, Tarcan T, Goldstein I, Siroky MB, Krane RJ, Azadzoi KM. Atherosclerosis-induced chronic arterial insufficiency causes clitoral cavernosal fibrosis in the rabbit. Int J Impot Res. 2000 Apr; 12(2):111-6. PMID: 11052638.
    View in: PubMed
  43. Tarcan T, Siroky MB, Krane RJ, Azadzoi KM. Isoprostane 8-epi PGF2alpha, a product of oxidative stress, is synthesized in the bladder and causes detrusor smooth muscle contraction. Neurourol Urodyn. 2000; 19(1):43-51. PMID: 10602247.
    View in: PubMed
  44. Azadzoi KM, Tarcan T, Kozlowski R, Krane RJ, Siroky MB. Overactivity and structural changes in the chronically ischemic bladder. J Urol. 1999 Nov; 162(5):1768-78. PMID: 10524933.
    View in: PubMed
  45. Azadzoi KM, Tarcan T, Siroky MB, Krane RJ. Atherosclerosis-induced chronic ischemia causes bladder fibrosis and non-compliance in the rabbit. J Urol. 1999 May; 161(5):1626-35. PMID: 10210430.
    View in: PubMed
  46. Azadzoi KM, Krane RJ, Saenz de Tejada I, Goldstein I, Siroky MB. Relative roles of cyclooxygenase and nitric oxide synthase pathways in ischemia-induced increased contraction of cavernosal smooth muscle. J Urol. 1999 Apr; 161(4):1324-8. PMID: 10081902.
    View in: PubMed
  47. Tarcan T, Park K, Goldstein I, Maio G, Fassina A, Krane RJ, Azadzoi KM. Histomorphometric analysis of age-related structural changes in human clitoral cavernosal tissue. J Urol. 1999 Mar; 161(3):940-4. PMID: 10022730.
    View in: PubMed
  48. Azadzoi KM, Goldstein I, Siroky MB, Traish AM, Krane RJ, Saenz de Tejada I. Mechanisms of ischemia-induced cavernosal smooth muscle relaxation impairment in a rabbit model of vasculogenic erectile dysfunction. J Urol. 1998 Dec; 160(6 Pt 1):2216-22. PMID: 9817373.
    View in: PubMed
  49. Tarcan T, Azadzoi KM, Siroky MB, Goldstein I, Krane RJ. Age-related erectile and voiding dysfunction: the role of arterial insufficiency. Br J Urol. 1998 Dec; 82 Suppl 1:26-33. PMID: 9883259.
    View in: PubMed
  50. Sadeghi-Nejad H, Moreland RB, Traish AM, Nehra A, Azadzoi KM, Goldstein I. Preliminary report on the development and characterization of rabbit clitoral smooth muscle cell culture. Int J Impot Res. 1998 Sep; 10(3):165-9. PMID: 9788105.
    View in: PubMed
  51. Nehra A, Azadzoi KM, Moreland RB, Pabby A, Siroky MB, Krane RJ, Goldstein I, Udelson D. Cavernosal expandability is an erectile tissue mechanical property which predicts trabecular histology in an animal model of vasculogenic erectile dysfunction. J Urol. 1998 Jun; 159(6):2229-36. PMID: 9598575.
    View in: PubMed
  52. Udelson D, Nehra A, Hatzichristou DG, Azadzoi K, Moreland RB, Krane RJ, Saenz de Tejada I, Goldstein I. Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part III--Clinical considerations of penile hemodynamic and rigidity erectile responses. Int J Impot Res. 1998 Jun; 10(2):89-99. PMID: 9647944.
    View in: PubMed
  53. Udelson D, Nehra A, Hatzichristou DG, Azadzoi K, Moreland RB, Krane RJ, Saenz de Tejada I, Goldstein I. Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part II--Clinical implications of penile buckling. Int J Impot Res. 1998 Mar; 10(1):25-35. PMID: 9542687.
    View in: PubMed
  54. Udelson D, Nehra A, Hatzichristou DG, Azadzoi K, Moreland RB, Krane J, Saenz de Tejada IS, Goldstein I. Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part I--Clinical implications of penile tissue mechanical properties. Int J Impot Res. 1998 Mar; 10(1):15-24. PMID: 9542686.
    View in: PubMed
  55. Park K, Goldstein I, Andry C, Siroky MB, Krane RJ, Azadzoi KM. Vasculogenic female sexual dysfunction: the hemodynamic basis for vaginal engorgement insufficiency and clitoral erectile insufficiency. Int J Impot Res. 1997 Mar; 9(1):27-37. PMID: 9138056.
    View in: PubMed
  56. Azadzoi KM, Park K, Andry C, Goldstein I, Siroky MB. Relationship between cavernosal ischemia and corporal veno-occlusive dysfunction in an animal model. J Urol. 1997 Mar; 157(3):1011-7. PMID: 9072535.
    View in: PubMed
  57. Azadzoi KM, Siroky MB, Goldstein I. Study of etiologic relationship of arterial atherosclerosis to corporal veno-occlusive dysfunction in the rabbit. J Urol. 1996 May; 155(5):1795-800. PMID: 8627886.
    View in: PubMed
  58. Azadzoi KM, Pontari M, Vlachiotis J, Siroky MB. Canine bladder blood flow and oxygenation: changes induced by filling, contraction and outlet obstruction. J Urol. 1996 Apr; 155(4):1459-65. PMID: 8632611.
    View in: PubMed
  59. Batista JE, Wagner JR, Azadzoi KM, Krane RJ, Siroky MB. Direct measurement of blood flow in the human bladder. J Urol. 1996 Feb; 155(2):630-3. PMID: 8558678.
    View in: PubMed
  60. Azadzoi KM, Vlachiotis J, Pontari M, Siroky MB. Hemodynamics of penile erection: III. Measurement of deep intracavernosal and subtunical blood flow and oxygen tension. J Urol. 1995 Feb; 153(2):521-6. PMID: 7815637.
    View in: PubMed
  61. Chiu AW, Azadzoi KM, Hatzichristou DG, Siroky MB, Krane RJ, Babayan RK. Effects of intra-abdominal pressure on renal tissue perfusion during laparoscopy. J Endourol. 1994 Apr; 8(2):99-103. PMID: 8061681.
    View in: PubMed
  62. Azadzoi KM, Saenz de Tejada I. Diabetes mellitus impairs neurogenic and endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle. J Urol. 1992 Nov; 148(5):1587-91. PMID: 1433573.
    View in: PubMed
  63. Azadzoi KM, Goldstein I. Erectile dysfunction due to atherosclerotic vascular disease: the development of an animal model. J Urol. 1992 Jun; 147(6):1675-81. PMID: 1593719.
    View in: PubMed
  64. Azadzoi KM, Kim N, Brown ML, Goldstein I, Cohen RA, Saenz de Tejada I. Endothelium-derived nitric oxide and cyclooxygenase products modulate corpus cavernosum smooth muscle tone. J Urol. 1992 Jan; 147(1):220-5. PMID: 1370329.
    View in: PubMed
  65. Azadzoi KM, Saenz de Tejada I. Hypercholesterolemia impairs endothelium-dependent relaxation of rabbit corpus cavernosum smooth muscle. J Urol. 1991 Jul; 146(1):238-40. PMID: 2056597.
    View in: PubMed
  66. Kim N, Azadzoi KM, Goldstein I, Saenz de Tejada I. A nitric oxide-like factor mediates nonadrenergic-noncholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle. J Clin Invest. 1991 Jul; 88(1):112-8. PMID: 1647413.
    View in: PubMed
  67. Saenz de Tejada I, Ware JC, Blanco R, Pittard JT, Nadig PW, Azadzoi KM, Krane RJ, Goldstein I. Pathophysiology of prolonged penile erection associated with trazodone use. J Urol. 1991 Jan; 145(1):60-4. PMID: 1984101.
    View in: PubMed
  68. Azadzoi KM, Payton T, Krane RJ, Goldstein I. Effects of intracavernosal trazodone hydrochloride: animal and human studies. J Urol. 1990 Nov; 144(5):1277-82. PMID: 1977931.
    View in: PubMed
  69. Saenz de Tejada I, Goldstein I, Azadzoi K, Krane RJ, Cohen RA. Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. N Engl J Med. 1989 Apr 20; 320(16):1025-30. PMID: 2927481.
    View in: PubMed
  70. Saenz de Tejada I, Blanco R, Goldstein I, Azadzoi K, de las Morenas A, Krane RJ, Cohen RA. Cholinergic neurotransmission in human corpus cavernosum. I. Responses of isolated tissue. Am J Physiol. 1988 Mar; 254(3 Pt 2):H459-67. PMID: 2894778.
    View in: PubMed
  71. Padma-Nathan H, Goldstein I, Azadzoi K, Blanco R, Saenz de Tejada I, Krane RJ. In vivo and in vitro studies on the physiology of penile erection. Semin Urol. 1986 Nov; 4(4):209-16. PMID: 2879330.
    View in: PubMed
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