Alpaslan Dedeoglu, MD, PhD
Associate Professor
Boston University School of Medicine
Dept of Neurology

MD, Istanbul University
PhD, Marmara University



VA Boston Healthcare System




Sphingosine-1-phosphate induced modulation of inflammation in aging and Alzheimer's disease
09/01/2017 - 06/30/2022 (PI)
NIH/National Institute on Aging
1RF1AG056032-01A1

Personnel Agreement for Research Services of Nurgul Aytan
09/15/2013 - 06/30/2017 (PI)
VA Boston Healthcare System


Fingolimod therapy in models of Alzheimer's disease
02/01/2015 - 08/01/2016 (PI)
Alzheimer's Drug Discovery Foundation


Interpersonnel Agreement for Sudarshana Sengupta
08/15/2014 - 09/14/2015 (PI)
VA Boston Healthcare System


Cyclohexanehexol Therapy in Transgenic Models of Alzheimer's Disease
09/15/2009 - 08/31/2015 (PI)
NIH/National Institute on Aging
5R01AG031896-05

Integrated Neuroimaging and Pathology of Alzheimer Mice
08/01/2005 - 07/31/2007 (PI)
NIH/National Institute on Aging
5 R21 AG025162 02

Anti-Inflammatory Therapy in a Mouse Model of Alzheimer’s Disease: A Magnetic Resonance Imaging, Spectroscopy and Quantitative Histopathological Study
08/01/2002 - 07/31/2004 (PI)
Alzheimer's Association




Yr Title Project-Sub Proj Pubs
2017 Sphingosine-1-phosphate induced modulation of inflammation in aging and Alzheimer's disease 1R01AG056032-01A1
2017 Novel neurotrophic therapies in an optimized mouse model of GWVI 5I01BX002468-04
2016 Novel neurotrophic therapies in an optimized mouse model of GWVI 5I01BX002468-03
2016 Cholinergic neurons and memory in GFP-AD mouse: a novel neurotrophic therapy 5I01BX001875-03
2015 Cholinergic neurons and memory in GFP-AD mouse: a novel neurotrophic therapy 5I01BX001875-02
2014 Novel neurotrophic therapies in an optimized mouse model of GWVI 1I01BX002468-01
2014 Cholinergic neurons and memory in GFP-AD mouse: a novel neurotrophic therapy 1I01BX001875-01A2
2014 Novel neurotrophic therapy in a mouse model of ALS 5I21BX001624-02
2013 Novel neurotrophic therapy in a mouse model of ALS 1I21BX001624-01
2013 Cyclohexanehexol Therapy in Transgenic Models of Alzheimer's Disease 5R01AG031896-05 5
Showing 10 of 16 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Kantarci A, Aytan N, Palaska I, Stephens D, Crabtree L, Benincasa C, Jenkins BG, Carreras I, Dedeoglu A. Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer''s disease. Exp Neurol. 2017 Nov 07; 300:111-120.View Related Profiles. PMID: 29126887.
  2. Aytan N, Choi JK, Carreras I, Brinkmann V, Kowall NW, Jenkins BG, Dedeoglu A. Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer''s disease. Sci Rep. 2016 04 27; 6:24939.View Related Profiles. PMID: 27117087; PMCID: PMC4847010; DOI: 10.1038/srep24939;.
  3. Jenkins BG, Zhu A, Poutiainen P, Choi JK, Kil KE, Zhang Z, Kuruppu D, Aytan N, Dedeoglu A, Brownell AL. Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration. Neuropharmacology. 2016 Sep; 108:462-73.View Related Profiles. PMID: 26581500; PMCID: PMC4896842; DOI: 10.1016/j.neuropharm.2015.11.010;.
  4. Choi JK, Carreras I, Aytan N, Jenkins-Sahlin E, Dedeoglu A, Jenkins BG. The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer''s disease mouse model using magnetic resonance spectroscopy and imaging. Brain Res. 2014 Nov 24; 1590:85-96.View Related Profiles. PMID: 25301691; PMCID: PMC4274938; DOI: 10.1016/j.brainres.2014.09.067;.
  5. Korkmaz OT, Aytan N, Carreras I, Choi JK, Kowall NW, Jenkins BG, Dedeoglu A. 7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis. Neurosci Lett. 2014 Apr 30; 566:286-91.View Related Profiles. PMID: 24637017; DOI: 10.1016/j.neulet.2014.02.058;.
  6. Zhu H, Wang X, Wallack M, Li H, Carreras I, Dedeoglu A, Hur JY, Zheng H, Li H, Fine R, Mwamburi M, Sun X, Kowall N, Stern RA, Qiu WQ. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer''s disease. Mol Psychiatry. 2015 Feb; 20(2):252-62.View Related Profiles. PMID: 24614496; PMCID: PMC4161670; DOI: 10.1038/mp.2014.17;.
  7. Carreras I, McKee AC, Choi JK, Aytan N, Kowall NW, Jenkins BG, Dedeoglu A. R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer''s disease. Brain Res. 2013 Dec 6; 1541:115-27.View Related Profiles. PMID: 24161403; PMCID: PMC3863610; DOI: 10.1016/j.brainres.2013.10.025;.
  8. Aytan N, Choi JK, Carreras I, Kowall NW, Jenkins BG, Dedeoglu A. Combination therapy in a transgenic model of Alzheimer''s disease. Exp Neurol. 2013 Dec; 250:228-38.View Related Profiles. PMID: 24120437; PMCID: PMC3926203; DOI: 10.1016/j.expneurol.2013.10.001;.
  9. Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013 Jan 30; 33(5):1927-39.View Related Profiles. PMID: 23365232; PMCID: PMC3711388; DOI: 10.1523/JNEUROSCI.2080-12.2013;.
  10. Choi JK, Carreras I, Dedeoglu A, Jenkins BG. Detection of increased scyllo-inositol in brain with magnetic resonance spectroscopy after dietary supplementation in Alzheimer's disease mouse models. Neuropharmacology. 2010 Sep-Oct; 59(4-5):353-7.View Related Profiles. PMID: 20399219; PMCID: PMC2926267; DOI: 10.1016/j.neuropharm.2010.03.011;.
Showing 10 of 44 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 44 publications over 15 distinct years, with a maximum of 9 publications in 2001

YearPublications
20004
20019
20026
20033
20043
20051
20072
20081
20094
20102
20133
20143
20151
20161
20171
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