Alpaslan Dedeoglu | Profiles RNS

Alpaslan Dedeoglu, MD, PhD

Associate Professor

Boston University Chobanian & Avedisian School of Medicine

Neurology

MD, Istanbul University
PhD, Marmara University

Websites

ResearchGate

ORCID : 0000-0003-1156-0874

Dr. Alpaslan Dedeoglu received his MD from the Istanbul University School of Medicine and completed a pharmacology program at the Marmara University in 1992. During and after his pharmacology program he worked at the University of Arizona, Ohio State University, and Massachusetts General Hospital; he then joined Boston University in 2000. Dr. Dedeoglu’s major research interests are neuroanatomy, neuropathology, and the neurochemistry of animal models of neurodegenerative disorders. His labs are located at the Boston VA Medical Center. Dr. Dedeoglu is the PI of several ongoing projects that are funded by the NIH, VA, and private foundations. He also works with therapeutic trials in rodent models of neurodegenerative disorders.

VA Boston Healthcare System

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences

Protective roles of taurine in Alzheimer's Disease brain
09/01/2020 - 08/31/2024 (Multi-PI)
PI: Alpaslan Dedeoglu, MD, PhD
Massachusetts General Hospital NIH NIA
1RF1AG069228-01

Mechanistic link between Alzheimer's disease and periodontitis
07/01/2019 - 06/30/2024 (Multi-PI)
PI: Alpaslan Dedeoglu, MD, PhD
NIH/National Institute on Aging
1RF1AG062496-01

Sphingosine-1-phosphate induced modulation of inflammation in aging and Alzheimer's disease
09/01/2017 - 08/31/2022 (PI)
NIH/National Institute on Aging
1RF1AG056032-01A1

Skeletal FGF23 production mediated by GPCR/Gq/PKC signaling
04/01/2021 - 03/31/2022 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NIDDK
3R01DK121776-02S1

XLas Relative to Gsa in Bone and Mineral Ion Metabolism
09/01/2018 - 11/30/2019 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NIDDK
3R01DK073911-10S1

Mechanisms of Resolvin E1 in Periodontal Regeneration (admin supplement)
09/01/2018 - 06/30/2019 (Subcontract PI)
Forsyth Institute NIH NIDCR
3R01DE025020-04S1

Personnel Agreement for Research Services of Nurgul Aytan
09/15/2013 - 06/30/2017 (PI)
VA Boston Healthcare System

Fingolimod therapy in models of Alzheimer's disease
02/01/2015 - 08/01/2016 (PI)
Alzheimer's Drug Discovery Foundation

Interpersonnel Agreement for Sudarshana Sengupta
08/15/2014 - 09/14/2015 (PI)
VA Boston Healthcare System

Cyclohexanehexol Therapy in Transgenic Models of Alzheimer's Disease
09/15/2009 - 08/31/2015 (PI)
NIH/National Institute on Aging
5R01AG031896-05

Showing 10 of 12 results. Show All Results

Title
Mechanistic Link Between Alzheimer's Disease and Periodontitis (PI)
Sphingosine-1-phosphate induced modulation of inflammation (PI)
XLas Relative to GSA in Bone and Mineral Ion Metabolism (PI)
Mouse Breeding Colonies for Neurodegenerative Diseases (PI)

Yr	Title	Project-Sub Proj	Pubs
2024	Sphingosine-1-phosphate system as a therapeutic target for amyotrophic lateral sclerosis	5I01BX005180-04
2024	Protective roles of taurine in Alzheimer's disease brain	4R01AG069228-02
2023	Sphingosine-1-phosphate system as a therapeutic target for amyotrophic lateral sclerosis	5I01BX005180-03
2022	Sphingosine-1-phosphate system as a therapeutic target for amyotrophic lateral sclerosis	5I01BX005180-02
2021	Sphingosine-1-phosphate system as a therapeutic target for amyotrophic lateral sclerosis	1I01BX005180-01
2021	Targeting the sphingosine-1-phosphate system in a mouse model of Gulf War Veterans' Illness	1I21BX004957-01
2021	Targeting the sphingosine-1-phosphate system in a mouse model of Gulf War Veterans' Illness	5I21BX004957-02
2020	Protective roles of taurine in Alzheimer's disease brain	1RF1AG069228-01
2019	Mechanistic link between Alzheimer's disease and periodontitis	1RF1AG062496-01	1
2017	Sphingosine-1-phosphate induced modulation of inflammation in aging and Alzheimer's disease	1RF1AG056032-01A1	1

Showing 10 of 27 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Jung Y, Ay B, Cyr SM, Tognoni CM, Klovdahl K, Matthias J, Cui Q, Brooks DJ, Bouxsein ML, Carreras I, Dedeoglu A, Bastepe M. Amyloid-ß neuropathology induces bone loss in male mice by suppressing bone formation and enhancing bone resorption. Bone Rep. 2024 Jun; 21:101771.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel

PMID: 38725879; PMCID: PMC11078651; DOI: 10.1016/j.bonr.2024.101771;

Ay B, Cyr SM, Klovdahl K, Zhou W, Tognoni CM, Iwasaki Y, Rhee EP, Dedeoglu A, Simic P, Bastepe M. Ga11 deficiency increases fibroblast growth factor 23 levels in a mouse model of familial hypocalciuric hypercalcemia. JCI Insight. 2024 Mar 26; 9(9).View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina

PMID: 38530370; PMCID: PMC11141917; DOI: 10.1172/jci.insight.178993;

Almarhoumi R, Alvarez C, Harris T, Tognoni CM, Paster BJ, Carreras I, Dedeoglu A, Kantarci A. Microglial cell response to experimental periodontal disease. J Neuroinflammation. 2023 Jun 14; 20(1):142.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel

PMID: 37316834; PMCID: PMC10265806; DOI: 10.1186/s12974-023-02821-x;

Carreras I, Jung Y, Lopez-Benitez J, Tognoni CM, Dedeoglu A. Fingolimod mitigates memory loss in a mouse model of Gulf War Illness amid decreasing the activation of microglia, protein kinase R, and NF?B. Neurotoxicology. 2023 May; 96:197-206.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel

PMID: 37160207; PMCID: PMC10334821; DOI: 10.1016/j.neuro.2023.05.006;

Jung Y, Lopez-Benitez J, Tognoni CM, Carreras I, Dedeoglu A. Dysregulation of sphingosine-1-phosphate (S1P) and S1P receptor 1 signaling in the 5xFAD mouse model of Alzheimer's disease. Brain Res. 2023 Jan 15; 1799:148171.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel

PMID: 36410428

Wu H, Qiu W, Zhu X, Li X, Xie Z, Carreras I, Dedeoglu A, Van Dyke T, Han YW, Karimbux N, Tu Q, Cheng L, Chen J. The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer's Pathogenesis via Specific Pathways. Front Aging Neurosci. 2022; 14:912709.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Van Dyke, Thomas

PMID: 35813949; PMCID: PMC9260256; DOI: 10.3389/fnagi.2022.912709;

Ma KS, Hasturk H, Carreras I, Dedeoglu A, Veeravalli JJ, Huang JY, Kantarci A, Wei JC. Dementia and the Risk of Periodontitis: A Population-Based Cohort Study. J Dent Res. 2022 03; 101(3):270-277.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel

PMID: 34643147; PMCID: PMC8982009; DOI: 10.1177/00220345211037220;

Kantarci A, Tognoni CM, Yaghmoor W, Marghalani A, Stephens D, Ahn JY, Carreras I, Dedeoglu A. Microglial response to experimental periodontitis in a murine model of Alzheimer's disease. Sci Rep. 2020 10 29; 10(1):18561.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel

PMID: 33122702; PMCID: PMC7596239; DOI: 10.1038/s41598-020-75517-4;

Pilozzi A, Yu Z, Carreras I, Cormier K, Hartley D, Rogers J, Dedeoglu A, Huang X. A Preliminary Study of Cu Exposure Effects upon Alzheimer's Amyloid Pathology. Biomolecules. 2020 03 06; 10(3).View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel

PMID: 32155778; PMCID: PMC7175127; DOI: 10.3390/biom10030408;

Carreras I, Aytan N, Choi JK, Tognoni CM, Kowall NW, Jenkins BG, Dedeoglu A. Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease. Sci Rep. 2019 07 29; 9(1):10972.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul

PMID: 31358793; PMCID: PMC6662857; DOI: 10.1038/s41598-019-47287-1;

Showing 10 of 58 results. Show More

Korkmaz OT, Ay H, Aytan N, Carreras I, Kowall NW, Dedeoglu A, Tuncel N. Vasoactive Intestinal Peptide Decreases ß-Amyloid Accumulation and Prevents Brain Atrophy in the 5xFAD Mouse Model of Alzheimer's Disease. J Mol Neurosci. 2019 Jul; 68(3):389-396.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul
Korkmaz, Orhan

PMID: 30498985

Carreras I, Aytan N, Mellott T, Choi JK, Lehar M, Crabtree L, Leite-Morris K, Jenkins BG, Blusztajn JK, Dedeoglu A. Corrigendum to "Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease" [Brain Res. 1681 (2018) 34-43]. Brain Res. 2018 06 01; 1688:113-115.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Blusztajn, Jan
Leite-Morris, Kimberly
Aytan, Nurgul
Mellott, Tiffany

PMID: 29526415

Aytan N, Choi JK, Carreras I, Crabtree L, Nguyen B, Lehar M, Blusztajn JK, Jenkins BG, Dedeoglu A. Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer's disease. Eur J Pharmacol. 2018 Jun 05; 828:9-17.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Blusztajn, Jan
Aytan, Nurgul

PMID: 29510124; PMCID: PMC5971844; DOI: 10.1016/j.ejphar.2018.02.045;

Carreras I, Aytan N, Mellott T, Choi JK, Lehar M, Crabtree L, Leite-Morris K, Jenkins BG, Blusztajn JK, Dedeoglu A. Anxiety, neuroinflammation, cholinergic and GABAergic abnormalities are early markers of Gulf War illness in a mouse model of the disease. Brain Res. 2018 02 15; 1681:34-43.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Blusztajn, Jan
Leite-Morris, Kimberly
Aytan, Nurgul
Mellott, Tiffany

PMID: 29277710; PMCID: PMC5971846; DOI: 10.1016/j.brainres.2017.12.030;

Kantarci A, Aytan N, Palaska I, Stephens D, Crabtree L, Benincasa C, Jenkins BG, Carreras I, Dedeoglu A. Combined administration of resolvin E1 and lipoxin A4 resolves inflammation in a murine model of Alzheimer's disease. Exp Neurol. 2018 02; 300:111-120.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Aytan, Nurgul

PMID: 29126887

Aytan N, Choi JK, Carreras I, Brinkmann V, Kowall NW, Jenkins BG, Dedeoglu A. Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer's disease. Sci Rep. 2016 04 27; 6:24939.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul

PMID: 27117087; PMCID: PMC4847010; DOI: 10.1038/srep24939;

Jenkins BG, Zhu A, Poutiainen P, Choi JK, Kil KE, Zhang Z, Kuruppu D, Aytan N, Dedeoglu A, Brownell AL. Functional modulation of G-protein coupled receptors during Parkinson disease-like neurodegeneration. Neuropharmacology. 2016 Sep; 108:462-73.View Related Profiles.

Dedeoglu, Alpaslan
Aytan, Nurgul

PMID: 26581500; PMCID: PMC4896842; DOI: 10.1016/j.neuropharm.2015.11.010;

Choi JK, Carreras I, Aytan N, Jenkins-Sahlin E, Dedeoglu A, Jenkins BG. The effects of aging, housing and ibuprofen treatment on brain neurochemistry in a triple transgene Alzheimer's disease mouse model using magnetic resonance spectroscopy and imaging. Brain Res. 2014 Nov 24; 1590:85-96.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Aytan, Nurgul

PMID: 25301691; PMCID: PMC4274938; DOI: 10.1016/j.brainres.2014.09.067;

Korkmaz OT, Aytan N, Carreras I, Choi JK, Kowall NW, Jenkins BG, Dedeoglu A. 7,8-Dihydroxyflavone improves motor performance and enhances lower motor neuronal survival in a mouse model of amyotrophic lateral sclerosis. Neurosci Lett. 2014 Apr 30; 566:286-91.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul
Korkmaz, Orhan

PMID: 24637017; PMCID: PMC5906793; DOI: 10.1016/j.neulet.2014.02.058;

Zhu H, Wang X, Wallack M, Li H, Carreras I, Dedeoglu A, Hur JY, Zheng H, Li H, Fine R, Mwamburi M, Sun X, Kowall N, Stern RA, Qiu WQ. Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer's disease. Mol Psychiatry. 2015 Feb; 20(2):252-62.View Related Profiles.

Dedeoglu, Alpaslan
Zhu, Haihao
Carreras, Isabel
Kowall, Neil
Fine, Richard
Stern, Robert
Qiu, Wendy

PMID: 24614496; PMCID: PMC4161670; DOI: 10.1038/mp.2014.17;

Carreras I, McKee AC, Choi JK, Aytan N, Kowall NW, Jenkins BG, Dedeoglu A. R-flurbiprofen improves tau, but not Aß pathology in a triple transgenic model of Alzheimer's disease. Brain Res. 2013 Dec 6; 1541:115-27.View Related Profiles.

Dedeoglu, Alpaslan
McKee, Ann
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul

PMID: 24161403; PMCID: PMC3863610; DOI: 10.1016/j.brainres.2013.10.025;

Aytan N, Choi JK, Carreras I, Kowall NW, Jenkins BG, Dedeoglu A. Combination therapy in a transgenic model of Alzheimer's disease. Exp Neurol. 2013 Dec; 250:228-38.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul

PMID: 24120437; PMCID: PMC3926203; DOI: 10.1016/j.expneurol.2013.10.001;

Chen CD, Sloane JA, Li H, Aytan N, Giannaris EL, Zeldich E, Hinman JD, Dedeoglu A, Rosene DL, Bansal R, Luebke JI, Kuro-o M, Abraham CR. The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS. J Neurosci. 2013 Jan 30; 33(5):1927-39.View Related Profiles.

Dedeoglu, Alpaslan
Abraham, Carmela
Chen, Ci-Di
Rosene, Douglas
Zeldich, Ella
Giannaris, Eustathia Lela
Luebke, Jennifer
Aytan, Nurgul

PMID: 23365232; PMCID: PMC3711388; DOI: 10.1523/JNEUROSCI.2080-12.2013;

Choi JK, Carreras I, Dedeoglu A, Jenkins BG. Detection of increased scyllo-inositol in brain with magnetic resonance spectroscopy after dietary supplementation in Alzheimer's disease mouse models. Neuropharmacology. 2010 Sep-Oct; 59(4-5):353-7.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel

PMID: 20399219; PMCID: PMC2926267; DOI: 10.1016/j.neuropharm.2010.03.011;

Choi JK, Dedeoglu A, Jenkins BG. Longitudinal monitoring of motor neuron circuitry in FALS rats using in-vivo phMRI. Neuroreport. 2010 Feb 17; 21(3):157-62. PMID: 20118741; PMCID: PMC2848450; DOI: 10.1097/WNR.0b013e328330eb9e;

Carreras I, Yuruker S, Aytan N, Hossain L, Choi JK, Jenkins BG, Kowall NW, Dedeoglu A. Moderate exercise delays the motor performance decline in a transgenic model of ALS. Brain Res. 2010 Feb 8; 1313:192-201.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul

PMID: 19968977; PMCID: PMC2892864; DOI: 10.1016/j.brainres.2009.11.051;

Choi JK, Küstermann E, Dedeoglu A, Jenkins BG. Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation. Eur J Neurosci. 2009 Dec; 30(11):2143-50. PMID: 19930399; PMCID: PMC2846694; DOI: 10.1111/j.1460-9568.2009.07015.x;

Choi JK, Jenkins BG, Carreras I, Kaymakcalan S, Cormier K, Kowall NW, Dedeoglu A. Anti-inflammatory treatment in AD mice protects against neuronal pathology. Exp Neurol. 2010 Jun; 223(2):377-84.View Related Profiles.

Dedeoglu, Alpaslan
Carreras, Isabel
Kowall, Neil

PMID: 19679126; PMCID: PMC2864355; DOI: 10.1016/j.expneurol.2009.07.032;

Aydin C, Aytan N, Mahon MJ, Tawfeek HA, Kowall NW, Dedeoglu A, Bastepe M. Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha). Endocrinology. 2009 Aug; 150(8):3567-75.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil
Aytan, Nurgul

PMID: 19423757; PMCID: PMC2717877; DOI: 10.1210/en.2009-0318;

McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res. 2008 May 1; 1207:225-36.View Related Profiles.

Dedeoglu, Alpaslan
McKee, Ann
Ryu, Hoon
Carreras, Isabel
Kowall, Neil

PMID: 18374906; PMCID: PMC2587244; DOI: 10.1016/j.brainres.2008.01.095;

Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ. Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. J Neurosci. 2007 Nov 21; 27(47):12908-15.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil

PMID: 18032664; PMCID: PMC6673303; DOI: 10.1523/JNEUROSCI.4318-07.2007;

Choi JK, Dedeoglu A, Jenkins BG. Application of MRS to mouse models of neurodegenerative illness. NMR Biomed. 2007 May; 20(3):216-37. PMID: 17451183

Jenkins BG, Andreassen OA, Dedeoglu A, Leavitt B, Hayden M, Borchelt D, Ross CA, Ferrante RJ, Beal MF. Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease. J Neurochem. 2005 Oct; 95(2):553-62. PMID: 16135087

Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Exp Gerontol. 2004 Nov-Dec; 39(11-12):1641-9.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil

PMID: 15582280

Dedeoglu A, Choi JK, Cormier K, Kowall NW, Jenkins BG. Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile. Brain Res. 2004 Jun 25; 1012(1-2):60-5.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil

PMID: 15158161

Brownell AL, Chen YI, Yu M, Wang X, Dedeoglu A, Cicchetti F, Jenkins BG, Beal MF. 3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy. J Neurochem. 2004 Jun; 89(5):1206-14. PMID: 15147513

Dedeoglu A, Kubilus JK, Yang L, Ferrante KL, Hersch SM, Beal MF, Ferrante RJ. Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice. J Neurochem. 2003 Jun; 85(6):1359-67. PMID: 12787055; PMCID: PMC2866522

Ryu H, Lee J, Olofsson BA, Mwidau A, Dedeoglu A, Escudero M, Flemington E, Azizkhan-Clifford J, Ferrante RJ, Ratan RR, Deodoglu A. Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway. Proc Natl Acad Sci U S A. 2003 Apr 1; 100(7):4281-6.View Related Profiles.

Dedeoglu, Alpaslan
Ryu, Hoon
Lee, Junghee

PMID: 12640146; PMCID: PMC153084

Holbert S, Dedeoglu A, Humbert S, Saudou F, Ferrante RJ, Néri C. Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease. Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5):2712-7. PMID: 12604778; PMCID: PMC151406

Andreassen OA, Dedeoglu A, Stanojevic V, Hughes DB, Browne SE, Leech CA, Ferrante RJ, Habener JF, Beal MF, Thomas MK. Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression. Neurobiol Dis. 2002 Dec; 11(3):410-24. PMID: 12586550

Dedeoglu A, Kubilus JK, Jeitner TM, Matson SA, Bogdanov M, Kowall NW, Matson WR, Cooper AJ, Ratan RR, Beal MF, Hersch SM, Ferrante RJ. Therapeutic effects of cystamine in a murine model of Huntington's disease. J Neurosci. 2002 Oct 15; 22(20):8942-50.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil

PMID: 12388601

Dedeoglu A, Ferrante RJ, Andreassen OA, Dillmann WH, Beal MF. Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid. Exp Neurol. 2002 Jul; 176(1):262-5. PMID: 12093104

Wendt S, Dedeoglu A, Speer O, Wallimann T, Beal MF, Andreassen OA. Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice. Free Radic Biol Med. 2002 May 1; 32(9):920-6. PMID: 11978494

Ferrante RJ, Andreassen OA, Dedeoglu A, Ferrante KL, Jenkins BG, Hersch SM, Beal MF. Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease. J Neurosci. 2002 Mar 1; 22(5):1592-9. PMID: 11880489

Kiechle T, Dedeoglu A, Kubilus J, Kowall NW, Beal MF, Friedlander RM, Hersch SM, Ferrante RJ. Cytochrome C and caspase-9 expression in Huntington's disease. Neuromolecular Med. 2002; 1(3):183-95.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil

PMID: 12095160

Bogdanov MB, Andreassen OA, Dedeoglu A, Ferrante RJ, Beal MF. Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease. J Neurochem. 2001 Dec; 79(6):1246-9. PMID: 11752065

Andreassen OA, Ferrante RJ, Dedeoglu A, Beal MF. Lipoic acid improves survival in transgenic mouse models of Huntington's disease. Neuroreport. 2001 Oct 29; 12(15):3371-3. PMID: 11711888

Ferrante RJ, Klein AM, Dedeoglu A, Beal MF. Therapeutic efficacy of EGb761 (Gingko biloba extract) in a transgenic mouse model of amyotrophic lateral sclerosis. J Mol Neurosci. 2001 Aug; 17(1):89-96. PMID: 11665866

Andreassen OA, Ferrante RJ, Huang HM, Dedeoglu A, Park L, Ferrante KL, Kwon J, Borchelt DR, Ross CA, Gibson GE, Beal MF. Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease. Ann Neurol. 2001 Jul; 50(1):112-7. PMID: 11456300

Andreassen OA, Dedeoglu A, Ferrante RJ, Jenkins BG, Ferrante KL, Thomas M, Friedlich A, Browne SE, Schilling G, Borchelt DR, Hersch SM, Ross CA, Beal MF. Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease. Neurobiol Dis. 2001 Jun; 8(3):479-91. PMID: 11447996

Andreassen OA, Ferrante RJ, Klivenyi P, Klein AM, Dedeoglu A, Albers DS, Kowall NW, Beal MF. Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Exp Neurol. 2001 Apr; 168(2):356-63.View Related Profiles.

Dedeoglu, Alpaslan
Kowall, Neil

PMID: 11259123

Andreassen OA, Dedeoglu A, Friedlich A, Ferrante KL, Hughes D, Szabo C, Beal MF. Effects of an inhibitor of poly(ADP-ribose) polymerase, desmethylselegiline, trientine, and lipoic acid in transgenic ALS mice. Exp Neurol. 2001 Apr; 168(2):419-24. PMID: 11259130

Andreassen OA, Jenkins BG, Dedeoglu A, Ferrante KL, Bogdanov MB, Kaddurah-Daouk R, Beal MF. Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation. J Neurochem. 2001 Apr; 77(2):383-90. PMID: 11299300

Andreassen OA, Ferrante RJ, Dedeoglu A, Albers DW, Klivenyi P, Carlson EJ, Epstein CJ, Beal MF. Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP. Exp Neurol. 2001 Jan; 167(1):189-95. PMID: 11161607

Andreassen OA, Dedeoglu A, Klivenyi P, Beal MF, Bush AI. N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis. Neuroreport. 2000 Aug 3; 11(11):2491-3. PMID: 10943709

Andreassen OA, Ferrante RJ, Hughes DB, Klivenyi P, Dedeoglu A, Ona VO, Friedlander RM, Beal MF. Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant. J Neurochem. 2000 Aug; 75(2):847-52. PMID: 10899963

Ferrante RJ, Andreassen OA, Jenkins BG, Dedeoglu A, Kuemmerle S, Kubilus JK, Kaddurah-Daouk R, Hersch SM, Beal MF. Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease. J Neurosci. 2000 Jun 15; 20(12):4389-97. PMID: 10844007

Klivenyi P, Andreassen OA, Ferrante RJ, Dedeoglu A, Mueller G, Lancelot E, Bogdanov M, Andersen JK, Jiang D, Beal MF. Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. J Neurosci. 2000 Jan 1; 20(1):1-7. PMID: 10627575

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 58 publications over 22 distinct years, with a maximum of 9 publications in 2001

Bar chart showing 58 publications over 22 distinct years, with a maximum of 9 publications in 2001

Year	Publications
2000	4
2001	9
2002	6
2003	3
2004	3
2005	1
2007	2
2008	1
2009	4
2010	2
2013	3
2014	3
2015	1
2016	1
2017	2
2018	3
2019	1
2020	2
2021	1
2022	2
2023	2
2024	2

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