Ronald J. Killiany, PhD
Associate Professor
Boston University School of Medicine
Dept of Anatomy & Neurobiology

PhD, Northeastern University
MA, University of Hartford



The underlying theme of my research has been to explore structure – function relationships in the brain. To this end, my work has focused on uncovering the morphological changes in the brain that are responsible for the cognitive decline seen in aging and disease processes. In initial studies, I used developmental techniques to examine specific structure-function relationships in the memory system of non-human primates. I continued on to conduct studies of normal aging and cerebrovascular disease. In this work I have focused on characterize the cognitive changes taking place in non-human primate models. As my interests in studying the brain grew, I become involved in structural Magnetic Resonance Imaging (MRI) studies of normal aging and disorders such as Alzheimer’s disease. In this work I have been quantifying volumetric changes taking place in the brain in the course of the disease processes. This work continues to evolve and has changed focus somewhat in the recent years to include studies aimed at exploring the value of MRI in predicting which subjects will progress to develop cognitive decline and Alzheimer’s disease and which will remain cognitively stable.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Associate Professor
Boston University School of Public Health
Environmental Health




Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)
08/24/2015 - 03/31/2018 (PI)
University of Southern California NIH NIA
5U01AG024904-10

Human Neurobiology Laboratory Support Contract with Pfizer
01/01/2014 - 12/31/2017 (SP Co-PI of Sub-Project / SP)
PI: Kevin C. Thomas, PhD
Pfizer, Inc.

ADNI-DOD-TAU, Effects of Traumatic Brain Injury and Post-Traumatic Stress Disorder and Alzheimer's Disease on Brain Tau in Vietnam Veterans using ADNI
09/22/2016 - 09/21/2017 (PI)
University of Southern California DOD Army Med Resrch

Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3)
09/15/2016 - 07/31/2017 (PI)
University of Southern California NIH NIA
2U19AG024904-11

Neurobiological Consequences of Hypertension and Age
03/01/2000 - 02/28/2010 (Co-PI)
NIH/National Institute on Aging
5 R37 AG17609 10

Age-Related Changes of Cognition in Health and Disease
08/01/2002 - 07/31/2007 (PI)
Massachusetts General Hospital NIH NIA

A Primate Model of Hypertensive Cerebrovascular
09/30/2002 - 08/31/2004 (PI)
NIH/National Institute on Aging
1 R03 AG21315 01




Yr Title Project-Sub Proj Pubs
2013 Whole Animal Imaging Core 3UC7AI070088-05S3-6801 1
2012 Whole Animal Imaging Core 3UC7AI070088-05S2-7841 1
2011 Whole Animal Imaging Core 3UC7AI070088-05S1-7216 1
2009 3T quasar dual MRI scanner for multimodal and molecular imaging 1S10RR025035-01
2002 Primate Model of Hypertensive Cerebrovascular Disease 1R03AG021315-01
2002 MAGNETIC RESONANCE IMAGING (MRI) 2P01AG004953-19-6 98
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Koo BB, Michalovicz LT, Calderazzo S, Kelly KA, Sullivan K, Killiany RJ, O''Callaghan JP. Corticosterone potentiates DFP-induced neuroinflammation and affects high-order diffusion imaging in a rat model of Gulf War Illness. Brain Behav Immun. 2017 Aug 04.View Related Profiles. PMID: 28782715.
  2. Farrar DC, Mian AZ, Budson AE, Moss MB, Koo BB, Killiany RJ. Retained executive abilities in mild cognitive impairment are associated with increased white matter network connectivity. Eur Radiol. 2017 Jul 10.View Related Profiles. PMID: 28695358.
  3. Bauer CM, Zajac LE, Koo BB, Killiany RJ, Merabet LB. Age-related changes in structural connectivity are improved using subject-specific thresholding. J Neurosci Methods. 2017 Aug 15; 288:45-56.View Related Profiles. PMID: 28647426.
  4. Thaker AA, Weinberg BD, Dillon WP, Hess CP, Cabral HJ, Fleischman DA, Leurgans SE, Bennett DA, Hyman BT, Albert MS, Killiany RJ, Fischl B, Dale AM, Desikan RS. Entorhinal Cortex: Antemortem Cortical Thickness and Postmortem Neurofibrillary Tangles and Amyloid Pathology. AJNR Am J Neuroradiol. 2017 May; 38(5):961-965.View Related Profiles. PMID: 28279988; DOI: 10.3174/ajnr.A5133;.
  5. Estrada LI, Robinson AA, Amaral AC, Giannaris EL, Heyworth NC, Mortazavi F, Ngwenya LB, Roberts DE, Cabral HJ, Killiany RJ, Rosene DL. Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry. J Histochem Cytochem. 2017 Mar; 65(3):153-171.View Related Profiles. PMID: 28080173; DOI: 10.1369/0022155416686934;.
  6. McKenna F, Koo BB, Killiany R. Comparison of ApoE-related brain connectivity differences in early MCI and normal aging populations: an fMRI study. Brain Imaging Behav. 2016 Dec; 10(4):970-983.View Related Profiles. PMID: 26409470.
  7. Moore TL, Pessina MA, Finklestein SP, Killiany RJ, Bowley B, Benowitz L, Rosene DL. Inosine enhances recovery of grasp following cortical injury to the primary motor cortex of the rhesus monkey. Restor Neurol Neurosci. 2016 Sep 21; 34(5):827-48.View Related Profiles. PMID: 27497459; DOI: 10.3233/RNN-160661;.
  8. He X, Koo BB, Killiany RJ. Edited Magnetic Resonance Spectroscopy Detects an Age-Related Decline in Nonhuman Primate Brain GABA Levels. Biomed Res Int. 2016; 2016:6523909.View Related Profiles. PMID: 27660760.
  9. Pham TA, Hua N, Phinikaridou A, Killiany R, Hamilton J. Early in vivo discrimination of vulnerable atherosclerotic plaques that disrupt: A serial MRI study. Atherosclerosis. 2016 Jan; 244:101-7.View Related Profiles. PMID: 26606442; DOI: 10.1016/j.atherosclerosis.2015.11.013;.
  10. Jack CR, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M. Magnetic resonance imaging in Alzheimer''s Disease Neuroimaging Initiative 2. Alzheimers Dement. 2015 Jul; 11(7):740-56. PMID: 26194310; PMCID: PMC4523217; DOI: 10.1016/j.jalz.2015.05.002;.
Showing 10 of 92 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 92 publications over 24 distinct years, with a maximum of 7 publications in 2005 and 2010

YearPublications
19931
19951
19961
19974
19981
19995
20001
20013
20024
20036
20042
20057
20066
20076
20086
20095
20107
20115
20124
20133
20144
20152
20163
20175
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Aging
Cerebrovascular disease
Cognition
Data analysis
Dementia
Experimental Design
Magnetic Resonance Imaging
Memory
Neuropsychology
Statistics

Available to Mentor as: (Review Mentor Role Definitions):
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  • Co-Mentor or Peer Mentor
  • Education Mentor
  • Research / Scholarly Mentor
Contact for Mentoring:


700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
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