Keywords
Last Name

Farzad Mortazavi, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentAnatomy & Neurobiology
Address700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Phone(617) 638-4134
Email
ORCID ORCID Icon0000-0002-1911-5428
 Research Expertise & Professional Interests
Dr. Mortazavi received his B.A. in psychology from the University of South Florida, M.S at Central Michigan University, and his Ph.D. at Northeastern University in Experimental Psychology and Behavioral Neuroscience. As a postdoctoral fellow, he was a Michel J. Fox Foundation Fellow in the Department of Neurology at UCLA where his studies focused on molecular and neuroanatomical changes in neurodegenerative disorders. He is currently an Assistant Professor in the Department of Anatomy and Neurobiology and his primary research is focused on 3D farzad_2reconstruction of white-matter pathways and cortical columns using Confocal Microscopy, 2-photon Microscopy and statistical physics for analysis of these types of big data. He also collaborates with Drs. Moss, Rosene, Killiany, and Moore in the Laboratory for Cognitive Neurobiology. The laboratory focuses on the effects of normal aging on structure and function of cerebral cortex and cortical ischemia in a non-human primate model.

Dr. Mortazavi teaches the statistics course in the department of Anatomy and Neurobiology and has been training students in immunohistochemistry, cell counts and image analysis among other techniques. He is actively involved in the Forensic Anthropology program where he teaches Experimental Design and Analysis for Forensic Anthropologists.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Richter F, Gabby L, McDowell KA, Mulligan CK, De La Rosa K, Sioshansi PC, Mortazavi F, Cely I, Ackerson LC, Tsan L, Murphy NP, Maidment NT, Chesselet MF. Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice. Neurobiol Aging. 2016 Dec 01; 51:54-66. PMID: 28038352.
    View in: PubMed
  2. Mortazavi F, Wang X, Rosene DL, Rockland KS. White Matter Neurons in Young Adult and Aged Rhesus Monkey. Front Neuroanat. 2016; 10:15. PMID: 26941613.
    View in: PubMed
  3. Farzad Mortazavi, Van J. Wedeen, Douglas L. Rosene. Axons and Brain Architecture; Edited by Kathleen S. Rockland. Chapter 17: Neuroanatomical Techniques for Analysis of Axonal Trajectories in the Cerebral Cortex of the Rhesus Monkey. Elsevier. Cambridge, MA. 2015; 349-366.
  4. Richter F, Fleming SM, Watson M, Lemesre V, Pellegrino L, Ranes B, Zhu C, Mortazavi F, Mulligan CK, Sioshansi PC, Hean S, De La Rosa K, Khanna R, Flanagan J, Lockhart DJ, Wustman BA, Clark SW, Chesselet MF. A GCase chaperone improves motor function in a mouse model of synucleinopathy. Neurotherapeutics. 2014 Oct; 11(4):840-56. PMID: 25037721.
    View in: PubMed
  5. Boaks A, Siwek D, Mortazavi F. The temporal degradation of bone collagen: A histochemical approach. Forensic Sci Int. 2014 Jul; 240:104-10. PMID: 24836839.
    View in: PubMed
  6. Wedeen VJ, Rosene DL, Wang R, Dai G, Mortazavi F, Hagmann P, Kaas JH, Tseng WY. Response to comment on "the geometric structure of the brain fiber pathways". Science. 2012 Sep 28; 337(6102):1605. PMID: 23019633.
    View in: PubMed
  7. Wedeen VJ, Rosene DL, Wang R, Dai G, Mortazavi F, Hagmann P, Kaas JH, Tseng WY. The geometric structure of the brain fiber pathways. Science. 2012 Mar 30; 335(6076):1628-34. PMID: 22461612.
    View in: PubMed
  8. Hutson CB, Lazo CR, Mortazavi F, Giza CC, Hovda D, Chesselet MF. Traumatic brain injury in adult rats causes progressive nigrostriatal dopaminergic cell loss and enhanced vulnerability to the pesticide paraquat. J Neurotrauma. 2011 Sep; 28(9):1783-801. PMID: 21644813.
    View in: PubMed
  9. Fleming SM, Mulligan CK, Richter F, Mortazavi F, Lemesre V, Frias C, Zhu C, Stewart A, Gozes I, Morimoto B, Chesselet MF. A pilot trial of the microtubule-interacting peptide (NAP) in mice overexpressing alpha-synuclein shows improvement in motor function and reduction of alpha-synuclein inclusions. Mol Cell Neurosci. 2011 Mar; 46(3):597-606. PMID: 21193046.
    View in: PubMed
  10. Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. J Neurosci. 2009 Feb 18; 29(7):1962-76. PMID: 19228951.
    View in: PubMed
  11. Chou AP, Maidment N, Klintenberg R, Casida JE, Li S, Fitzmaurice AG, Fernagut PO, Mortazavi F, Chesselet MF, Bronstein JM. Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome. J Biol Chem. 2008 Dec 12; 283(50):34696-703. PMID: 18818210.
    View in: PubMed
  12. Chesselet MF, Fleming S, Mortazavi F, Meurers B. Strengths and limitations of genetic mouse models of Parkinson's disease. Parkinsonism Relat Disord. 2008; 14 Suppl 2:S84-7. PMID: 18585084.
    View in: PubMed
  13. Trksak GH, Glatt SJ, Mortazavi F, Jackson D. A meta-analysis of animal studies on disruption of spatial navigation by prenatal cocaine exposure. Neurotoxicol Teratol. 2007 Sep-Oct; 29(5):570-7. PMID: 17683902.
    View in: PubMed
  14. Mortazavi F, Ericson M, Story D, Hulce VD, Dunbar GL. Spatial learning deficits and emotional impairments in pentylenetetrazole-kindled rats. Epilepsy Behav. 2005 Dec; 7(4):629-38. PMID: 16246633.
    View in: PubMed
Farzad's Networks
Click the "See All" links for more information and interactive visualizations!
Concepts
_
BU Co-Authors
_
Similar BU People
_
Same Department