Keywords
Last Name

Tara L. Moore, PhD

TitleAssociate Professor
InstitutionBoston University School of Medicine
DepartmentAnatomy & Neurobiology
Address700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Phone(617) 638-4054
ORCID ORCID Icon0000-0003-3869-3837
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

TitleAssociate Professor
InstitutionBoston University School of Medicine
DepartmentNeurology

 Research Expertise & Professional Interests
My primary research interests involve the investigation of the recovery of fine motor function and re-organization of the motor cortex following cortical injury. Using a non-human primate (NHP) model of cortical injury developed with Dr. Rosene, we are establishing the rate and pattern of recovery of fine motor function of the hand and the histopathological response of the brain to injury in this model with young and aged NHPs. Additional studies with this model include assessing the efficacy of various therapeutics to enhance the recovery of function following ischemia.

In addition, we are conducting studies with Pfizer, Inc to assess the efficacy of various pharmaceutical therapies for slowing or reversing age-related cognitive decline in non-human primates.

Finally, as part of my role as director of the MS in Forensic Anthropology I also participate in studies of the rate and process of decomposition in a cold climate using a porcine model.

 Self-Described Keywords
  • aging
  • cortical injury
  • non-human primates
  • recovery
  • stroke
  • pharmaceutical collaborations
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Newcomb AM, Pokines JT, Moore TL. Taphonomic Effects of Mechanical Plowing on Buried Juvenile-Sized Remains. J Forensic Sci. 2017 Jan; 62(1):67-73. PMID: 27864968.
    View in: PubMed
  2. Pokines JT, Sussman R, Gough M, Ralston C, McLeod E, Brun K, Kearns A, Moore TL. Taphonomic Analysis of Rodentia and Lagomorpha Bone Gnawing Based Upon Incisor Size. J Forensic Sci. 2017 Jan; 62(1):50-66. PMID: 27859293.
    View in: PubMed
  3. Moore TL, Pessina MA, Finklestein SP, Killiany RJ, Bowley B, Benowitz L, Rosene DL. Inosine enhances recovery of grasp following cortical injury to the primary motor cortex of the rhesus monkey. Restor Neurol Neurosci. 2016 Sep 21; 34(5):827-48. PMID: 27497459.
    View in: PubMed
  4. Ngwenya LB, Heyworth NC, Shwe Y, Moore TL, Rosene DL. Age-related changes in dentate gyrus cell numbers, neurogenesis, and associations with cognitive impairments in the rhesus monkey. Front Syst Neurosci. 2015; 9:102. PMID: 26236203.
    View in: PubMed
  5. Moore TL, Pessina MA, Finklestein SP, Kramer BC, Killiany RJ, Rosene DL. Recovery of fine motor performance after ischemic damage to motor cortex is facilitated by cell therapy in the rhesus monkey. Somatosens Mot Res. 2013 Dec; 30(4):185-96. PMID: 23758412.
    View in: PubMed
  6. Moore TL, Schettler SP, Killiany RJ, Rosene DL, Moss MB. Impairment in delayed nonmatching to sample following lesions of dorsal prefrontal cortex. Behav Neurosci. 2012 Dec; 126(6):772-80. PMID: 23088539.
    View in: PubMed
  7. Moore TL, Killiany RJ, Pessina MA, Moss MB, Finklestein SP, Rosene DL. Recovery from ischemia in the middle-aged brain: a nonhuman primate model. Neurobiol Aging. 2012 Mar; 33(3):619.e9-619.e24. PMID: 21458887.
    View in: PubMed
  8. Minett WJ, Moore TL, Juhascik MP, Nields HM, Hull MJ. Concentrations of opiates and psychotropic agents in polydrug overdoses: a surprising correlation between morphine and antidepressants. J Forensic Sci. 2010 Sep; 55(5):1319-25. PMID: 20456586.
    View in: PubMed
  9. Moore TL, Killiany RJ, Pessina MA, Moss MB, Rosene DL. Assessment of motor function of the hand in aged rhesus monkeys. Somatosens Mot Res. 2010; 27(3):121-30. PMID: 20653499.
    View in: PubMed
  10. Moore TL, Schettler SP, Killiany RJ, Rosene DL, Moss MB. Effects on executive function following damage to the prefrontal cortex in the rhesus monkey (Macaca mulatta). Behav Neurosci. 2009 Apr; 123(2):231-41. PMID: 19331446.
    View in: PubMed
  11. Makris N, Papadimitriou GM, van der Kouwe A, Kennedy DN, Hodge SM, Dale AM, Benner T, Wald LL, Wu O, Tuch DS, Caviness VS, Moore TL, Killiany RJ, Moss MB, Rosene DL. Frontal connections and cognitive changes in normal aging rhesus monkeys: a DTI study. Neurobiol Aging. 2007 Oct; 28(10):1556-67. PMID: 16962214.
    View in: PubMed
  12. Hynynen K, McDannold N, Clement G, Jolesz FA, Zadicario E, Killiany R, Moore T, Rosen D. Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain--a primate study. Eur J Radiol. 2006 Aug; 59(2):149-56. PMID: 16716552.
    View in: PubMed
  13. Moore TL, Killiany RJ, Herndon JG, Rosene DL, Moss MB. Executive system dysfunction occurs as early as middle-age in the rhesus monkey. Neurobiol Aging. 2006 Oct; 27(10):1484-93. PMID: 16183172.
    View in: PubMed
  14. Moore TL, Killiany RJ, Herndon JG, Rosene DL, Moss MB. A non-human primate test of abstraction and set shifting: an automated adaptation of the Wisconsin Card Sorting Test. J Neurosci Methods. 2005 Aug 15; 146(2):165-73. PMID: 16054506.
    View in: PubMed
  15. Lacreuse A, Kim CB, Rosene DL, Killiany RJ, Moss MB, Moore TL, Chennareddi L, Herndon JG. Sex, age, and training modulate spatial memory in the rhesus monkey (Macaca mulatta). Behav Neurosci. 2005 Feb; 119(1):118-26. PMID: 15727518.
    View in: PubMed
  16. Moore TL, Schettler SP, Killiany RJ, Herndon JG, Luebke JI, Moss MB, Rosene DL. Cognitive impairment in aged rhesus monkeys associated with monoamine receptors in the prefrontal cortex. Behav Brain Res. 2005 May 28; 160(2):208-21. PMID: 15863218.
    View in: PubMed
  17. Luebke JI, Chang YM, Moore TL, Rosene DL. Normal aging results in decreased synaptic excitation and increased synaptic inhibition of layer 2/3 pyramidal cells in the monkey prefrontal cortex. Neuroscience. 2004; 125(1):277-88. PMID: 15051166.
    View in: PubMed
  18. Moore TL, Killiany RJ, Herndon JG, Rosene DL, Moss MB. Impairment in abstraction and set shifting in aged rhesus monkeys. Neurobiol Aging. 2003 Jan-Feb; 24(1):125-34. PMID: 12493558.
    View in: PubMed
  19. Moore TL, Killiany RJ, Rosene DL, Prusty S, Hollander W, Moss MB. Hypertension-induced changes in monoamine receptors in the prefrontal cortex of rhesus monkeys. Neuroscience. 2003; 120(1):177-89. PMID: 12849751.
    View in: PubMed
  20. Moore TL, Killiany RJ, Rosene DL, Prusty S, Hollander W, Moss MB. Impairment of executive function induced by hypertension in the rhesus monkey (Macaca mulatta). Behav Neurosci. 2002 Jun; 116(3):387-96. PMID: 12049319.
    View in: PubMed
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