Neema Yazdani
Pre-Doctoral Trainee
Boston University School of Medicine, Division of Graduate Medical Sciences
Dept of Pharmacology & Experimental Therapeutics




Laboratory of Addiction Genetics (Advisor: Dr. Camron Bryant), Department of Pharmacology, Boston University, Boston, MA

Graduate student (PhD); 2013-present
• Utilized TALENs gene editing to generate Hnrnph1 & Rufy1 knock-out mice
• Established & managed large-scale mouse breeding colonies for multiple strains
• Developed custom qPCR, PCR, & restriction enzyme-based genotyping protocols
• Mastered open field, elevated plus maze, & conditioned place preference behavioral assessments
• Executed bioinformatic transcriptome & spice variant analyses
• Established & optimized a mouse brain tissue immunohistochemistry pipeline
• Spearheaded interdisciplinary collaborations with local & offsite laboratories
• Mentored undergraduates in various laboratory & behavioral techniques

Department of Biology (Advisor: Dr. Eduardo Macagno), UCSD, La Jolla, CA

Undergraduate researcher & graduate student (M.S.); 2011-2012
• Mastered recombinant DNA techniques including primer design, PCR, restriction enzyme digests, gel electrophoresis, insert-vector ligations & bacterial cloning
• Conducted single-neuron injections & leech embryo dissections
• Delivered expression vectors on gold particles biolistically to neurons in vivo using a gene gun
• Executed neural immunohistology & confocal imaging
• Designed & optimized RNA probes for in situ hybridization of newly discovered Innexin genes

Saier Lab, Department of Biology, Section of Molecular Biology, UCSD, La Jolla, CA

Undergraduate researcher; 2008
• Trained in using NCBI GenBank, BLAST, & ClustalW online programs
• Categorized bacterial monovalent cation transporters by amino acid homology

Pre-Doctoral Trainee
Boston University School of Medicine, Division of Graduate Medical Sciences
Program in Biomedical Neuroscience



2015 Boston University: International Behavioural and Neural Genetics Society (IBANGS) Travel Award & Talk ($1,500)
2015 Boston University: BU Genome Science Institute Research Symposium Award & Talk ($100)
2014-2016 Boston University: Transformative Training Program in Addiction Science (TTPAS) Fellowship ($64,000)
2014 Boston University: BU Genome Science Institute Research Symposium Poster Award ($100)
2014 Boston University: IBANGS Travel Award ($400)
2014 Boston University: TTPAS Travel Award for Jackson Laboratory “Short Course on Addiction Genetics” ($1,800)
2013-2014 Boston University: NIGMS Training Program in Biomolecular Pharmacology, 5T32GM008541-18 ($31,000


Functional Mechanisms of Hnrnph1 in Methamphetamine Addictive Behaviors
04/01/2016 - 03/31/2018 (PI)
NIH/National Institute on Drug Abuse
5F31DA040324-02



Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Goldberg LR, Kirkpatrick SL, Yazdani N, Luttik KP, Lacki OA, Babbs RK, Jenkins DF, Johnson WE, Bryant CD. Casein kinase 1-epsilon deletion increases mu opioid receptor-dependent behaviors and binge eating. Genes Brain Behav. 2017 Jun 08.View Related Profiles. PMID: 28594147.
  2. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Biol Psychiatry. 2017 May 01; 81(9):757-769.View Related Profiles. PMID: 27914629; DOI: 10.1016/j.biopsych.2016.10.021;.
  3. Yazdani N, Shen Y, Johnson WE, Bryant CD. Striatal transcriptome analysis of a congenic mouse line (chromosome 11: 50-60Mb) exhibiting reduced methamphetamine sensitivity. Genom Data. 2016 Jun; 8:77-80.View Related Profiles. PMID: 27222804; DOI: 10.1016/j.gdata.2016.03.009;.
  4. Bryant CD, Yazdani N. RNA-binding proteins, neural development and the addictions. Genes Brain Behav. 2016 Jan; 15(1):169-86.View Related Profiles. PMID: 26643147; PMCID: PMC4944654; DOI: 10.1111/gbb.12273;.
  5. Yazdani N, Parker CC, Shen Y, Reed ER, Guido MA, Kole LA, Kirkpatrick SL, Lim JE, Sokoloff G, Cheng R, Johnson WE, Palmer AA, Bryant CD. Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity. PLoS Genet. 2015 Dec; 11(12):e1005713.View Related Profiles. PMID: 26658939; PMCID: PMC4675533; DOI: 10.1371/journal.pgen.1005713;.
  6. Baker MW, Yazdani N, Macagno ER. Gap junction-dependent homolog avoidance in the developing CNS. J Neurosci. 2013 Oct 16; 33(42):16673-83. PMID: 24133270; DOI: 10.1523/JNEUROSCI.2387-13.2013;.
  7. Yazdani N, Firme CP, Macagno ER, Baker MW. Expression of a dominant negative mutant innexin in identified neurons and glial cells reveals selective interactions among gap junctional proteins. Dev Neurobiol. 2013 Aug; 73(8):571-86. PMID: 23447124; DOI: 10.1002/dneu.22082;.
  8. Firme CP, Natan RG, Yazdani N, Macagno ER, Baker MW. Ectopic expression of select innexins in individual central neurons couples them to pre-existing neuronal or glial networks that express the same innexin. J Neurosci. 2012 Oct 10; 32(41):14265-70. PMID: 23055495; PMCID: PMC3703444; DOI: 10.1523/JNEUROSCI.2693-12.2012;.
  9. Kandarian B, Sethi J, Wu A, Baker M, Yazdani N, Kym E, Sanchez A, Edsall L, Gaasterland T, Macagno E. The medicinal leech genome encodes 21 innexin genes: different combinations are expressed by identified central neurons. Dev Genes Evol. 2012 Mar; 222(1):29-44. PMID: 22358128; DOI: 10.1007/s00427-011-0387-z;.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 9 publications over 5 distinct years, with a maximum of 3 publications in 2016

YearPublications
20122
20132
20151
20163
20171
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72 E. Concord St Evans Building
Boston MA 02118
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