Pietro Cottone, PhD
Associate Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

PhD, University of Rome
MS, University of Palermo
PharmD, University of Palermo



Dr. Cottone is co-director of the Laboratory of Addictive Disorders. Dr. Cottone’s research interests focus on the neurobiological substrates of motivated behaviors including feeding and addiction. The major goal of Dr. Cottone’s research is identifying the biological bases of and potential treatments for eating disorders and obesity. Current studies concern the role of stress in compulsive eating and palatable food dependence. Areas of focused research include the investigation of the neurobiological bases of stress-related disorders such as anxiety and depression. Dr. Cottone’s studies are carried out on environmental and genetic animal models, using behavioral, biochemical, and molecular approaches.

Dr. Cottone co-directs a graduate course in neuropsychopharmacology offered for the first time in Fall 2010 which examines the interaction between behavior and classes of drugs that affect the central nervous system.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Associate Professor
Boston University School of Medicine
Psychiatry



2010-2014 National Institutes of Health/National Institute of Mental Health: Biobehavioral Research Awards for Innovative New Scientists (BRAINS)
2010-2014 Boston University School of Medicine: Peter Paul Career Development Professorship
2008 of Modena and Reggio Emilia, Italy: Paolo Guidetti Award, CINSPAN
2007-2011 National Institute on Drug Abuse (NIDA): NIH Pathway to Independence Award (K99/R00)
2003-2007 University of Rome La Sapienza, Rome, Italy: Merit Predoctoral Fellowship for Graduate Studies
2003 University of Palermo, Palermo, Italy: Undergraduate Merit Fellowship


Neurobiology of Compulsive Eating
03/01/2011 - 02/28/2017 (PI)
NIH/National Institute on Drug Abuse
5R01DA030425-05

Role of the Endocannabinoid System in Compulsive Eating
07/15/2010 - 03/31/2016 (PI)
NIH/National Institute of Mental Health
5R01MH091945-05




Yr Title Project-Sub Proj Pubs
2015 Neurobiology of compulsive eating. 5R01DA030425-05 20
2014 Neurobiology of compulsive eating. 5R01DA030425-04 20
2014 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-05 18
2013 Neurobiology of compulsive eating. 5R01DA030425-03 20
2013 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-04 18
2012 Neurobiology of compulsive eating. 5R01DA030425-02 20
2012 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-03 18
2011 Neurobiology of compulsive eating. 1R01DA030425-01A1 20
2011 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-02 18
2011 The dark side of preferred food addiction: role of CRF systems 5R00DA023680-05 14
Showing 10 of 15 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Moore CF, Sabino V, Koob GF, Cottone P. Neuroscience of Compulsive Eating Behavior. Front Neurosci. 2017; 11:469.View Related Profiles. PMID: 28883784.
  2. Sabino V, Hicks C, Cottone P. Sigma Receptors and Substance Use Disorders. Adv Exp Med Biol. 2017; 964:177-199.View Related Profiles. PMID: 28315272; DOI: 10.1007/978-3-319-50174-1_13;.
  3. Sabino V, Cottone P. Sigma Receptors and Alcohol Use Disorders. Handb Exp Pharmacol. 2017; 244:219-236.View Related Profiles. PMID: 28039543; DOI: 10.1007/164_2016_97;.
  4. Moore CF, Sabino V, Koob GF, Cottone P. Pathological Overeating: Emerging Evidence for a Compulsivity Construct. Neuropsychopharmacology. 2017 Jun; 42(7):1375-1389.View Related Profiles. PMID: 27922596; DOI: 10.1038/npp.2016.269;.
  5. Kirkpatrick SL, Goldberg LR, Yazdani N, Babbs RK, Wu J, Reed ER, Jenkins DF, Bolgioni AF, Landaverde KI, Luttik KP, Mitchell KS, Kumar V, Johnson WE, Mulligan MK, Cottone P, Bryant CD. Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating. Biol Psychiatry. 2017 May 01; 81(9):757-769.View Related Profiles. PMID: 27914629; DOI: 10.1016/j.biopsych.2016.10.021;.
  6. Iemolo A, Seiglie M, Blasio A, Cottone P, Sabino V. Pituitary adenylate cyclase-activating polypeptide (PACAP) in the central nucleus of the amygdala induces anxiety via melanocortin receptors. Psychopharmacology (Berl). 2016 Sep; 233(17):3269-77.View Related Profiles. PMID: 27376948; PMCID: PMC4982769; DOI: 10.1007/s00213-016-4366-y;.
  7. Giuliano C, Cottone P. The role of the opioid system in binge eating disorder. CNS Spectr. 2015 Dec; 20(6):537-45. PMID: 26499083; PMCID: PMC4831059; DOI: 10.1017/S1092852915000668;.
  8. Valenza M, DiLeo A, Steardo L, Cottone P, Sabino V. Ethanol-related behaviors in mice lacking the sigma-1 receptor. Behav Brain Res. 2016 Jan 15; 297:196-203.View Related Profiles. PMID: 26462569; DOI: 10.1016/j.bbr.2015.10.013;.
  9. Seiglie MP, Smith KL, Blasio A, Cottone P, Sabino V. Pituitary adenylate cyclase-activating polypeptide induces a depressive-like phenotype in rats. Psychopharmacology (Berl). 2015 Oct; 232(20):3821-31.View Related Profiles. PMID: 26264905; PMCID: PMC4565740; DOI: 10.1007/s00213-015-4045-4;.
  10. Valenza M, Steardo L, Cottone P, Sabino V. Diet-induced obesity and diet-resistant rats: differences in the rewarding and anorectic effects of D-amphetamine. Psychopharmacology (Berl). 2015 Sep; 232(17):3215-26.View Related Profiles. PMID: 26047964; PMCID: PMC4536171; DOI: 10.1007/s00213-015-3981-3;.
Showing 10 of 51 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 50 publications over 12 distinct years, with a maximum of 8 publications in 2015

YearPublications
20062
20075
20085
20094
20102
20113
20124
20137
20144
20158
20163
20173
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72 E. Concord St Housman (R)
Boston MA 02118
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