Pietro Cottone, PhD
Associate Professor
Boston University School of Medicine
Dept of Pharmacology & Experimental Therapeutics

PhD, University of Rome
MS, University of Palermo
PharmD, University of Palermo

Dr. Cottone is co-director of the Laboratory of Addictive Disorders. Dr. Cottone’s research interests focus on the neurobiological substrates of motivated behaviors including feeding and addiction. The major goal of Dr. Cottone’s research is identifying the biological bases of and potential treatments for eating disorders and obesity. Current studies concern the role of stress in compulsive eating and palatable food dependence. Areas of focused research include the investigation of the neurobiological bases of stress-related disorders such as anxiety and depression. Dr. Cottone’s studies are carried out on environmental and genetic animal models, using behavioral, biochemical, and molecular approaches.

Dr. Cottone co-directs a graduate course in neuropsychopharmacology offered for the first time in Fall 2010 which examines the interaction between behavior and classes of drugs that affect the central nervous system.

Associate Professor
Boston University School of Medicine

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

2010-2014 National Institutes of Health/National Institute of Mental Health: Biobehavioral Research Awards for Innovative New Scientists (BRAINS)
2010-2014 Boston University School of Medicine: Peter Paul Career Development Professorship
2008 of Modena and Reggio Emilia, Italy: Paolo Guidetti Award, CINSPAN
2007-2011 National Institute on Drug Abuse (NIDA): NIH Pathway to Independence Award (K99/R00)
2003-2007 University of Rome La Sapienza, Rome, Italy: Merit Predoctoral Fellowship for Graduate Studies
2003 University of Palermo, Palermo, Italy: Undergraduate Merit Fellowship

Determining the role of PACAP neuronal populations in alcohol drinking using PACAP-Cre mice
04/20/2018 - 03/31/2021 (PI)
NIH/National Institute on Alcohol Abuse and Alcoholism

Effects of Samidorphan on olanzapine-induced overeating
12/13/2019 - 12/13/2020 (PI)

Neurobiology of Compulsive Eating
03/01/2011 - 02/28/2017 (PI)
NIH/National Institute on Drug Abuse

Role of the Endocannabinoid System in Compulsive Eating
07/15/2010 - 03/31/2016 (PI)
NIH/National Institute of Mental Health


Yr Title Project-Sub Proj Pubs
2019 Determining the role of PACAP neuronal populations in alcohol drinking using PACAP-Cre mice 5R21AA026051-02
2018 Determining the role of PACAP neuronal populations in alcohol drinking using PACAP-Cre mice 1R21AA026051-01A1
2015 Neurobiology of compulsive eating. 5R01DA030425-05 33
2014 Neurobiology of compulsive eating. 5R01DA030425-04 33
2014 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-05 25
2013 Neurobiology of compulsive eating. 5R01DA030425-03 33
2013 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-04 25
2012 Neurobiology of compulsive eating. 5R01DA030425-02 33
2012 Role of the Endocannabinoid System in Compulsive Eating 5R01MH091945-03 25
2011 Neurobiology of compulsive eating. 1R01DA030425-01A1 33
Showing 10 of 17 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Quadir SG, Tanino SM, Sami YN, Minnig MA, Iyer MR, Rice KC, Cottone P, Sabino V. Antagonism of Sigma-1 receptor blocks heavy alcohol drinking and associated hyperalgesia in male mice. Alcohol Clin Exp Res. 2021 Jul; 45(7):1398-1407.View Related Profiles. PMID: 34060104
  2. Quadir SG, Tanino SM, Rohl CD, Sahn JJ, Yao EJ, Cruz LDR, Cottone P, Martin SF, Sabino V. The Sigma-2 receptor / transmembrane protein 97 (s2R/TMEM97) modulator JVW-1034 reduces heavy alcohol drinking and associated pain states in male mice. Neuropharmacology. 2021 02 15; 184:108409.View Related Profiles. PMID: 33221481; PMCID: PMC7856185; DOI: 10.1016/j.neuropharm.2020.108409;
  3. Ferragud A, Velazquez-Sanchez C, Minnig MA, Sabino V, Cottone P. Pituitary adenylate cyclase-activating polypeptide (PACAP) modulates dependence-induced alcohol drinking and anxiety-like behavior in male rats. Neuropsychopharmacology. 2021 02; 46(3):509-518.View Related Profiles. PMID: 33191400; PMCID: PMC8027820; DOI: 10.1038/s41386-020-00904-4;
  4. Lee HS, Giunti E, Sabino V, Cottone P. Consummatory, Feeding Microstructural, and Metabolic Effects Induced by Limiting Access to Either a High-Sucrose or a High-Fat Diet. Nutrients. 2020 May 30; 12(6).View Related Profiles. PMID: 32486207; PMCID: PMC7352440; DOI: 10.3390/nu12061610;
  5. Hicks C, Sabino V, Cottone P. The Alpha-1 Adrenergic Receptor Antagonist Prazosin Reduces Binge-Like Eating in Rats. Nutrients. 2020 May 28; 12(6).View Related Profiles. PMID: 32481494; PMCID: PMC7352795; DOI: 10.3390/nu12061569;
  6. Ferragud A, Velázquez-Sánchez C, Abdullatif AA, Sabino V, Cottone P. Withdrawal from Extended, Intermittent Access to A Highly Palatable Diet Impairs Hippocampal Memory Function and Neurogenesis: Effects of Memantine. Nutrients. 2020 May 23; 12(5).View Related Profiles. PMID: 32456193; PMCID: PMC7284648; DOI: 10.3390/nu12051520;
  7. Quadir SG, Rohl CD, Zeabi A, Moore CF, Cottone P, Sabino V. Effect of different standard rodent diets on ethanol intake and associated allodynia in male mice. Alcohol. 2020 09; 87:17-23.View Related Profiles. PMID: 32330590; PMCID: PMC7812484; DOI: 10.1016/j.alcohol.2020.04.003;
  8. Valenza M, Blasio A, DiLeo A, Cottone P, Sabino V. Sigma receptor-induced heavy drinking in rats: Modulation by the opioid receptor system. Pharmacol Biochem Behav. 2020 05; 192:172914.View Related Profiles. PMID: 32205151
  9. Moore CF, Leonard MZ, Micovic NM, Miczek KA, Sabino V, Cottone P. Reward sensitivity deficits in a rat model of compulsive eating behavior. Neuropsychopharmacology. 2020 03; 45(4):589-596.View Related Profiles. PMID: 31622973; PMCID: PMC7021808; DOI: 10.1038/s41386-019-0550-1;
  10. Seiglie MP, Huang L, Cottone P, Sabino V. Role of the PACAP system of the extended amygdala in the acoustic startle response in rats. Neuropharmacology. 2019 12 01; 160:107761.View Related Profiles. PMID: 31493466; PMCID: PMC6842120; DOI: 10.1016/j.neuropharm.2019.107761;
Showing 10 of 69 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 68 publications over 16 distinct years, with a maximum of 8 publications in 2015

Contact for Mentoring:

72 E. Concord St Housman (R)
Boston MA 02118
Google Map

Cottone's Networks
Click the "See All" links for more information and interactive visualizations
Media Mentions
Similar People
Same Department