Conan Kornetsky, PhD
|Institution||Boston University School of Medicine|
|Address||72 E. Concord St Instructional (L)|
Boston MA 02118
|2011||University of Maine Alumni Association:
Bernard Lown Humanitarian Award|
|2010||University of Kentucky:
Distinguished Alumnus, Department of Psychology|
|2005||College on Problems of Drug Dependence:
Nathan B. Eddy Award for Excellence in Drug Abuse Research|
|2002||College of Problems of Drug Dependence:
|1997||-||1998||University of Kentucky:
Distinguished Alumnus, Department of Psychology |
|1990||American Association for the Advancement of Science:
|1985||-||1986||Division of Psychopharmacology of The American Psychological Association:
Research Interests: Neuronal Bases for the Rewarding Effects of Abused Substances
Research in the behavioral pharmacology laboratory is directed toward the determination of neuronal mechanisms involved in the behavioral effects of drugs. Much of this research is focused on the brain’s motivational systems. Changes in these systems are directly related to the rewarding effects associated with the action of the abused psychomotor stimulants, e.g., cocaine and opioids, e.g., heroin. There is reason to believe that these same systems are also affected, albeit in opposite ways, in clinical depression and anxiety. The research of graduate students in this laboratory will continue to study the mechanisms involved in the rewarding actions of these abused substances using the following techniques and procedures: stereotaxic surgery for implanting intercerebral stimulating electrodes and/or cannulae directly into specific brain sites, the use of psychophysical methods for determining thresholds for various types of intracerebral electrical stimulation (e.g., appetitive, aversive), the use of an intravenous drug self-administration model in rats, the use of the quantitative 2-[14C] deoxyglucose method for determining cerebral metabolic rates of glucose in specific brain areas, and the evaluation of brain-stimulation reward in knockout mice models.
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