Neil Kowall | Profiles RNS

Neil W. Kowall, MD

Professor

Boston University School of Medicine

Dept of Neurology

MD, University of British Columbia

Websites

Neurology Faculty

ORCID : 0000-0002-6624-0213

Dr. Neil W. Kowall was born in Calgary, Canada and graduated with his MD from the University of British Columbia. He moved to Boston for postgraduate training in Internal Medicine at the Beth Israel Deaconess Hospital followed by a Neurology residency at Massachusetts General Hospital. After finishing his clinical training, he completed a postdoctoral research fellowship and was appointed Assistant Professor of Neurology at Massachusetts General Hospital and Harvard Medical School. He moved to the VA and Boston University in 1992 where he is currently Professor of Neurology and Pathology, Chief of Neurology at VA Boston Healthcare System, Director of the VA New England Geriatric Research Education and Clinical Center and Director of the NIH-funded Boston University Alzheimer’s Disease Center. He has published over 199 original reports. His major research interests are human neuroanatomy and neuropathology and the use of animal models to test novel therapies for neurodegenerative diseases including Alzheimer’s disease. Dr. Kowall’s research interests include the following: human neuroanatomy, immunocytochemistry and enzyme histochemistry of the brain, neuropathological basis of neurological disorders, animal models of neurological diseases, geriatric neurology, and cognitive decline in the elderly.

Professor
Boston University School of Medicine
Pathology & Laboratory Medicine

Director of Alzheimer's Disease Center
Boston University School of Medicine
Dean’s Office

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences

VA Boston Healthcare System

Multi-center development of a novel diagnostic test for Alzheimer's disease
09/01/2018 - 05/31/2023 (Multi-PI)
PI: Neil W. Kowall, MD
NIH/National Institute on Aging
5R01AG059424-03

Boston University Alzheimer's Disease Center
07/01/2017 - 06/30/2021 (PI)
NIH/National Institute on Aging
5P30AG013846-23

National Alzheimer's Coordinating Center (NACC)
07/01/2015 - 06/30/2021 (Subcontract PI)
University of Washington NIH NIA
3U01AG016976-20S9

Boston University Alzheimer's Disease Center
09/15/2016 - 06/30/2017 (PI)
NIH/National Institute on Aging
3P30AG013846-20S1

Boston University Alzheimer's Disease Core Center
07/01/2014 - 06/30/2017 (PI)
NIH/National Institute on Aging
5P30AG013846-20

Alzheimer's Disease Neuroimaging Initiative
09/30/2010 - 07/31/2016 (Subcontract PI)
University of California, San Diego NIH NIA
5U01AG024904-09

Alzheimer's Disease Neuroimaging Initiative
09/30/2010 - 07/31/2016 (Subcontract PI)
University of California, San Diego NIH NIA
5U01AG024904-09

National Alzheimer's Coordinating Center (NACC)
07/01/2015 - 06/30/2016 (Subcontract PI)
University of Washington NIH NIA
2U01AG016976-16

Boston University Alzheimer's Disease Core Center
07/01/2006 - 06/30/2016 (PI)
NIH/National Institute on Aging
5P30AG013846-18

Alzheimer's Disease Translational Research Training
05/01/2011 - 04/30/2016 (PI)
NIH/National Institute on Aging
5T32AG036697-05

Showing 10 of 22 results. Show All Results

Title
National Alzheimer's Coordinating Center (NACC) Yr4/5
VA Biorespository: Gulf War Veterans Illnesses Biorepository
VA Biorepository Brain Bank
VA Biorespository Brain Bank: The National PTSD Brain Bank
Boston University Alzheimer Disease Core Center

Yr	Title	Project-Sub Proj	Pubs
2020	Boston University Alzheimer's Disease Center	3P30AG013846-23S3	874
2020	Multi-center development of a novel diagnostic test for Alzheimer's disease	5R01AG059424-03	2
2020	VA Biorepository: Gulf War Veterans' Illnesses Biorepository	2I01BX003063-05A1
2020	VA Biorepository Brain Bank	5I01BX002466-07	8
2019	Multi-center development of a novel diagnostic test for Alzheimer's disease	5R01AG059424-02	2
2019	VA Biorepository Brain Bank	5I01BX002466-06	8
2019	Boston University Alzheimer's Disease Center	3P30AG013846-23S1	874
2019	Boston University Alzheimer's Disease Center	5P30AG013846-23	874
2019	Boston University Alzheimer's Disease Center	3P30AG013846-23S2	874
2019	Core A: Administrative Core	5P30AG013846-23-6894	874

Showing 10 of 110 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 Jan 01; 78(1):102-113.View Related Profiles.

Jun, Gyungah
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Kowall, Neil

PMID: 33074286

Alosco ML, Tripodis Y, Rowland B, Chua AS, Liao H, Martin B, Jarnagin J, Chaisson CE, Pasternak O, Karmacharya S, Koerte IK, Cantu RC, Kowall NW, McKee AC, Shenton ME, Greenwald R, McClean M, Stern RA, Lin A. A magnetic resonance spectroscopy investigation in symptomatic former NFL players. Brain Imaging Behav. 2020 Oct; 14(5):1419-1429.View Related Profiles.

McKee, Ann
Alosco, Michael
McClean, Michael
Kowall, Neil
Stern, Robert
Cantu, Robert
Tripodis, Yorghos

PMID: 30848432; DOI: 10.1007/s11682-019-00060-4;

Adams JW, Alosco ML, Mez J, Alvarez VE, Huber BR, Tripodis Y, Adler CH, Kubilius C, Cormier KA, Mathais R, Nicks R, Kelley HJ, Saltiel N, Uretsky M, Nair E, Aytan N, Cherry JD, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, McKee AC, Stein TD. Association of probable REM sleep behavior disorder with pathology and years of contact sports play in chronic traumatic encephalopathy. Acta Neuropathol. 2020 12; 140(6):851-862.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Katz, Douglas
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Aytan, Nurgul
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 32939646

Alosco ML, Cherry JD, Huber BR, Tripodis Y, Baucom Z, Kowall NW, Saltiel N, Goldstein LE, Katz DI, Dwyer B, Daneshvar DH, Palmisano JN, Martin B, Cantu RC, Stern RA, Alvarez VE, Mez J, Stein TD, McKee AC. Characterizing tau deposition in chronic traumatic encephalopathy (CTE): utility of the McKee CTE staging scheme. Acta Neuropathol. 2020 10; 140(4):495-512.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Daneshvar, Daniel
Katz, Douglas
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 32778942

Spencer KR, Foster ZW, Rauf NA, Guilderson L, Collins D, Averill JG, Walker SE, Robey I, Cherry JD, Alvarez VE, Huber BR, McKee AC, Kowall NW, Brady CB, Stein TD. Neuropathological profile of long-duration amyotrophic lateral sclerosis in military Veterans. Brain Pathol. 2020 11; 30(6):1028-1040.View Related Profiles.

McKee, Ann
Huber, Bertrand
Brady, Christopher
Cherry, Jonathan
Kowall, Neil
Stein, Thor
Alvarez, Victor

PMID: 32633852

Cho H, Hyeon SJ, Shin JY, Alvarez VE, Stein TD, Lee J, Kowall NW, McKee AC, Ryu H, Seo JS. Alterations of transcriptome signatures in head trauma-related neurodegenerative disorders. Sci Rep. 2020 06 01; 10(1):8811.View Related Profiles.

McKee, Ann
Ryu, Hoon
Kowall, Neil
Stein, Thor
Alvarez, Victor

PMID: 32483284

Sugarman MA, Zetterberg H, Blennow K, Tripodis Y, McKee AC, Stein TD, Martin B, Palmisano JN, Steinberg EG, Simkin I, Budson AE, Killiany R, O'Connor MK, Au R, Qiu WWQ, Goldstein LE, Kowall NW, Mez J, Stern RA, Alosco ML. A longitudinal examination of plasma neurofilament light and total tau for the clinical detection and monitoring of Alzheimer's disease. Neurobiol Aging. 2020 10; 94:60-70.View Related Profiles.

Budson, Andrew
McKee, Ann
Mez, Jesse
Goldstein, Lee
O'Connor, Maureen
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 32585491; DOI: 10.1016/j.neurobiolaging.2020.05.011;

Lee MY, Lee J, Hyeon SJ, Cho H, Hwang YJ, Shin JY, McKee AC, Kowall NW, Kim JI, Stein TD, Hwang D, Ryu H. Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease. Aging Cell. 2020 06; 19(6):e13153.View Related Profiles.

McKee, Ann
Ryu, Hoon
Kowall, Neil
Stein, Thor

PMID: 32419307

Shin S, Kim D, Song JY, Jeong H, Hyeon SJ, Kowall NW, Ryu H, Pae AN, Lim S, Kim YK. Visualization of soluble tau oligomers in TauP301L-BiFC transgenic mice demonstrates the progression of tauopathy. Prog Neurobiol. 2020 Feb 24; 101782.View Related Profiles.

Ryu, Hoon
Kowall, Neil

PMID: 32105751

Heo JY, Nam MH, Yoon HH, Kim J, Hwang YJ, Won W, Woo DH, Lee JA, Park HJ, Jo S, Lee MJ, Kim S, Shim JE, Jang DP, Kim KI, Huh SH, Jeong JY, Kowall NW, Lee J, Im H, Park JH, Jang BK, Park KD, Lee HJ, Shin H, Cho IJ, Hwang EM, Kim Y, Kim HY, Oh SJ, Lee SE, Paek SH, Yoon JH, Jin BK, Kweon GR, Shim I, Hwang O, Ryu H, Jeon SR, Lee CJ. Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease. Curr Biol. 2020 01 20; 30(2):276-291.e9.View Related Profiles.

Ryu, Hoon
Kowall, Neil

PMID: 31928877

Showing 10 of 245 results. Show More

Pelcher I, Puzo C, Tripodis Y, Aparicio HJ, Steinberg EG, Phelps A, Martin B, Palmisano JN, Vassey E, Lindbergh C, McKee AC, Stein TD, Killiany RJ, Au R, Kowall NW, Stern RA, Mez J, Alosco ML. Revised Framingham Stroke Risk Profile: Association with Cognitive Status and MRI-Derived Volumetric Measures. J Alzheimers Dis. 2020; 78(4):1393-1408.View Related Profiles.

McKee, Ann
Vassey, Elizabeth
Aparicio, Hugo
Mez, Jesse
Alosco, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 33164933

Mez J, Daneshvar DH, Abdolmohammadi B, Chua AS, Alosco ML, Kiernan PT, Evers L, Marshall L, Martin BM, Palmisano JN, Nowinski CJ, Mahar I, Cherry JD, Alvarez VE, Dwyer B, Huber BR, Stein TD, Goldstein LE, Katz DI, Cantu RC, Au R, Kowall NW, Stern RA, McClean MD, Weuve J, Tripodis Y, McKee AC. Duration of American Football Play and Chronic Traumatic Encephalopathy. Ann Neurol. 2020 01; 87(1):116-131.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Nowinski, Christopher
Daneshvar, Daniel
Katz, Douglas
Mahar, Ian
Weuve, Jennifer
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
McClean, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 31589352; DOI: 10.1002/ana.25611;

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. Author CoView Related Profiles.

Beiser, Alexa
DeStefano, Anita
McKee, Ann
Sarnowski, Chloe
Jun, Gyungah
Himali, Jayandra
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil
Yang, Qiong
Stern, Robert
Seshadri, Sudha

PMID: 31417202; DOI: 10.1038/s41588-019-0495-7;

Alosco ML, Stein TD, Tripodis Y, Chua AS, Kowall NW, Huber BR, Goldstein LE, Cantu RC, Katz DI, Palmisano JN, Martin B, Cherry JD, Mahar I, Killiany RJ, McClean MD, Au R, Alvarez V, Stern RA, Mez J, McKee AC. Association of White Matter Rarefaction, Arteriolosclerosis, and Tau With Dementia in Chronic Traumatic Encephalopathy. JAMA Neurol. 2019 Aug 05.View Related Profiles.

McKee, Ann
Huber, Bertrand
Katz, Douglas
Mahar, Ian
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
McClean, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 31380975; DOI: 10.1001/jamaneurol.2019.2244;

Carreras I, Aytan N, Choi JK, Tognoni CM, Kowall NW, Jenkins BG, Dedeoglu A. Dual dose-dependent effects of fingolimod in a mouse model of Alzheimer's disease. Sci Rep. 2019 07 29; 9(1):10972.View Related Profiles.

Dedeoglu, Alpaslan
Tognoni, Christina
Carreras, Isabel
Kowall, Neil
Aytan, Nurgul

PMID: 31358793

Puzo C, Labriola C, Sugarman MA, Tripodis Y, Martin B, Palmisano JN, Steinberg EG, Stein TD, Kowall NW, McKee AC, Mez J, Killiany RJ, Stern RA, Alosco ML. Independent effects of white matter hyperintensities on cognitive, neuropsychiatric, and functional decline: a longitudinal investigation using the National Alzheimer's Coordinating Center Uniform Data Set. Alzheimers Res Ther. 2019 07 27; 11(1):64.View Related Profiles.

McKee, Ann
Mez, Jesse
Alosco, Michael
Kowall, Neil
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 31351489; DOI: 10.1186/s13195-019-0521-0;

Kim YH, Shim HS, Kim KH, Lee J, Chung BC, Kowall NW, Ryu H, Lee J. Metabolomic Analysis Identifies Alterations of Amino Acid Metabolome Signatures in the Postmortem Brain of Alzheimer's Disease. Exp Neurobiol. 2019 Jun; 28(3):376-389.View Related Profiles.

Ryu, Hoon
Lee, Junghee
Kowall, Neil

PMID: 31308797

Bi B, Choi HP, Hyeon SJ, Sun S, Su N, Liu Y, Lee J, Kowall NW, McKee AC, Yang JH, Ryu H. Quantitative Proteomic Analysis Reveals Impaired Axonal Guidance Signaling in Human Postmortem Brain Tissues of Chronic Traumatic Encephalopathy. Exp Neurobiol. 2019 Jun; 28(3):362-375.View Related Profiles.

McKee, Ann
Choi, Han-Pil
Ryu, Hoon
Kowall, Neil

PMID: 31308796

Standring OJ, Friedberg J, Tripodis Y, Chua AS, Cherry JD, Alvarez VE, Huber BR, Xia W, Mez J, Alosco ML, Nicks R, Mahar I, Pothast MJ, Gardner HM, Meng G, Palmisano JN, Martin BM, Dwyer B, Kowall NW, Cantu RC, Goldstein LE, Katz DI, Stern RA, McKee AC, Stein TD. Contact sport participation and chronic traumatic encephalopathy are associated with altered severity and distribution of cerebral amyloid angiopathy. Acta Neuropathol. 2019 09; 138(3):401-413.View Related Profiles.

McKee, Ann
Huber, Bertrand
Dwyer, Brigid
Katz, Douglas
Mahar, Ian
Friedberg, Jacob
Mez, Jesse
Cherry, Jonathan
Goldstein, Lee
Alosco, Michael
Kowall, Neil
Stern, Robert
Stein, Thor
Alvarez, Victor
Xia, Weiming
Tripodis, Yorghos

PMID: 31183671

Sugarman MA, McKee AC, Stein TD, Tripodis Y, Besser LM, Martin B, Palmisano JN, Steinberg EG, O'Connor MK, Au R, McClean M, Killiany R, Mez J, Weiner MW, Kowall NW, Stern RA, Alosco ML. Failure to detect an association between self-reported traumatic brain injury and Alzheimer's disease neuropathology and dementia. Alzheimers Dement. 2019 05; 15(5):686-698.View Related Profiles.

McKee, Ann
Mez, Jesse
O'Connor, Maureen
Alosco, Michael
McClean, Michael
Kowall, Neil
Au, Rhoda
Stern, Robert
Killiany, Ronald
Stein, Thor
Tripodis, Yorghos

PMID: 30852157; DOI: 10.1016/j.jalz.2018.12.015;

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PMID: 30820047; DOI: 10.1038/s41588-019-0358-2;

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PMID: 30299493

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PMID: 30498985

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PMID: 30481590

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Tripodis, Yorghos

PMID: 30390709

Adams JW, Alvarez VE, Mez J, Huber BR, Tripodis Y, Xia W, Meng G, Kubilus CA, Cormier K, Kiernan PT, Daneshvar DH, Chua AS, Svirsky S, Nicks R, Abdolmohammadi B, Evers L, Solomon TM, Cherry JD, Aytan N, Mahar I, Devine S, Auerbach S, Alosco ML, Nowinski CJ, Kowall NW, Goldstein LE, Dwyer B, Katz DI, Cantu RC, Stern RA, Au R, McKee AC, Stein TD. Lewy Body Pathology and Chronic Traumatic Encephalopathy Associated With Contact Sports. J Neuropathol Exp Neurol. 2018 09 01; 77(9):757-768.View Related Profiles.

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Tripodis, Yorghos

PMID: 30053297

Ashendorf L, Alosco ML, Bing-Canar H, Chapman KR, Martin B, Chaisson CE, Dixon D, Steinberg EG, Tripodis Y, Kowall NW, Stern RA. Clinical Utility of Select Neuropsychological Assessment Battery Tests in Predicting Functional Abilities in Dementia. Arch Clin Neuropsychol. 2018 Aug 01; 33(5):530-540.View Related Profiles.

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Tripodis, Yorghos

PMID: 29126099; DOI: 10.1093/arclin/acx100;

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McKee, Ann
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Stein, Thor
Tripodis, Yorghos

PMID: 29710395

Nicolas A, Kenna KP, Renton AE, Ticozzi N, Faghri F, Chia R, Dominov JA, Kenna BJ, Nalls MA, Keagle P, Rivera AM, van Rheenen W, Murphy NA, van Vugt JJFA, Geiger JT, Van der Spek RA, Pliner HA, Shankaracharya, Smith BN, Marangi G, Topp SD, Abramzon Y, Gkazi AS, Eicher JD, Kenna A, Mora G, Calvo A, Mazzini L, Riva N, Mandrioli J, Caponnetto C, Battistini S, Volanti P, La Bella V, Conforti FL, Borghero G, Messina S, Simone IL, Trojsi F, Salvi F, Logullo FO, D'Alfonso S, Corrado L, Capasso M, Ferrucci L, Moreno CAM, Kamalakaran S, Goldstein DB, Gitler AD, Harris T, Myers RM, Phatnani H, Musunuri RL, Evani US, Abhyankar A, Zody MC, Kaye J, Finkbeiner S, Wyman SK, LeNail A, Lima L, Fraenkel E, Svendsen CN, Thompson LM, Van Eyk JE, Berry JD, Miller TM, Kolb SJ, Cudkowicz M, Baxi E, Benatar M, Taylor JP, Rampersaud E, Wu G, Wuu J, Lauria G, Verde F, Fogh I, Tiloca C, Comi GP, Sorarù G, Cereda C, Corcia P, Laaksovirta H, Myllykangas L, Jansson L, Valori M, Ealing J, Hamdalla H, Rollinson S, Pickering-Brown S, Orrell RW, Sidle KC, Malaspina A, Hardy J, Singleton AB, Johnson JO, Arepalli S, Sapp PC, McKenna-Yasek D, Polak M, Asress S, Al-Sarraj S, King A, Troakes C, Vance C, de Belleroche J, Baas F, Ten Asbroek ALMA, Muñoz-Blanco JL, Hernandez DG, Ding J, Gibbs JR, Scholz SW, Floeter MK, Campbell RH, Landi F, Bowser R, Pulst SM, Ravits JM, MacGowan DJL, Kirby J, Pioro EP, Pamphlett R, Broach J, Gerhard G, Dunckley TL, Brady CB, Kowall NW, Troncoso JC, Le Ber I, Mouzat K, Lumbroso S, Heiman-Patterson TD, Kamel F, Van Den Bosch L, Baloh RH, Strom TM, Meitinger T, Shatunov A, Van Eijk KR, de Carvalho M, Kooyman M, Middelkoop B, Moisse M, McLaughlin RL, Van Es MA, Weber M, Boylan KB, Van Blitterswijk M, Rademakers R, Morrison KE, Basak AN, Mora JS, Drory VE, Shaw PJ, Turner MR, Talbot K, Hardiman O, Williams KL, Fifita JA, Nicholson GA, Blair IP, Rouleau GA, Esteban-Pérez J, García-Redondo A, Al-Chalabi A, Rogaeva E, Zinman L, Ostrow LW, Maragakis NJ, Rothstein JD, Simmons Z, Cooper-Knock J, Brice A, Goutman SA, Feldman EL, Gibson SB, Taroni F, Ratti A, Gellera C, Van Damme P, Robberecht W, Fratta P, Sabatelli M, Lunetta C, Ludolph AC, Andersen PM, Weishaupt JH, Camu W, Trojanowski JQ, Van Deerlin VM, Brown RH, van den Berg LH, Veldink JH, Harms MB, Glass JD, Stone DJ, Tienari P, Silani V, Chiò A, Shaw CE, Traynor BJ, Landers JE. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron. 2018 03 21; 97(6):1268-1283.e6.View Related Profiles.

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PMID: 29566793

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Stein, Thor
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PMID: 29360998; DOI: 10.1093/brain/awx350;

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PMID: 29480193

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PMID: 29843242; DOI: 10.3233/JAD-180017;

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PMID: 29130578

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McKee, Ann
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PMID: 28840457

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Huber, Bertrand
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Kowall, Neil
Stern, Robert
Cantu, Robert
Stein, Thor
Alvarez, Victor
Tripodis, Yorghos

PMID: 28742910; DOI: 10.1001/jama.2017.8334;

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, et al. RarView Related Profiles.

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O'Donnell, Christopher
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Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil
Yang, Qiong
Stern, Robert
Seshadri, Sudha

PMID: 28714976

Lee J, Hwang YJ, Kim Y, Lee MY, Hyeon SJ, Lee S, Kim DH, Jang SJ, Im H, Min SJ, Choo H, Pae AN, Kim DJ, Cho KS, Kowall NW, Ryu H. Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease. Acta Neuropathol. 2017 Nov; 134(5):729-748.View Related Profiles.

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PMID: 28593442

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Ryu, Hoon
Lee, Junghee
Kowall, Neil
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PMID: 28524178

Galetta KM, Chapman KR, Essis MD, Alosco ML, Gillard D, Steinberg E, Dixon D, Martin B, Chaisson CE, Kowall NW, Tripodis Y, Balcer LJ, Stern RA. Screening Utility of the King-Devick Test in Mild Cognitive Impairment and Alzheimer Disease Dementia. Alzheimer Dis Assoc Disord. 2017 Apr-Jun; 31(2):152-158.View Related Profiles.

Chaisson, Christine
Alosco, Michael
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Stern, Robert
Tripodis, Yorghos

PMID: 27299935

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Wolozin, Benjamin
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Kowall, Neil
Stein, Thor

PMID: 28363773; DOI: 10.1016/j.neuropharm.2017.03.030;

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PMID: 28304301; DOI: 10.3233/JAD-161205;

Zhu H, Stern RA, Tao Q, Bourlas A, Essis MD, Chivukula M, Rosenzweig J, Steenkamp D, Xia W, Mercier GA, Tripodis Y, Farlow M, Kowall N, Qiu WQ. An amylin analog used as a challenge test for Alzheimer's disease. Alzheimers Dement (N Y). 2017 Jan; 3(1):33-43.View Related Profiles.

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Xia, Weiming
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PMID: 28503657; DOI: 10.1016/j.trci.2016.12.002;

Tripodis Y, Alosco ML, Zirogiannis N, Gavett BE, Chaisson C, Martin B, McClean MD, Mez J, Kowall N, Stern RA. The Effect of Traumatic Brain Injury History with Loss of Consciousness on Rate of Cognitive Decline Among Older Adults with Normal Cognition and Alzheimer's Disease Dementia. J Alzheimers Dis. 2017; 59(1):251-263.View Related Profiles.

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Mez, Jesse
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Casey, Noel
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Lee J, Hong YK, Jeon GS, Hwang YJ, Kim KY, Seong KH, Jung MK, Picketts DJ, Kowall NW, Cho KS, Ryu H. ATRX induction by mutant huntingtin via Cdx2 modulates heterochromatin condensation and pathology in Huntington's disease. Cell Death Differ. 2012 Jul; 19(7):1109-16.View Related Profiles.

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Lee J, Kosaras B, Del Signore SJ, Cormier K, McKee A, Ratan RR, Kowall NW, Ryu H. Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington's disease mice. Acta Neuropathol. 2011 Apr; 121(4):487-98.View Related Profiles.

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van der Steen JT, Lane P, Kowall NW, Knol DL, Volicer L. Antibiotics and mortality in patients with lower respiratory infection and advanced dementia. J Am Med Dir Assoc. 2012 Feb; 13(2):156-61. PMID: 21450193; DOI: 10.1016/j.jamda.2010.07.001;

McKee AC, Gavett BE, Stern RA, Nowinski CJ, Cantu RC, Kowall NW, Perl DP, Hedley-Whyte ET, Price B, Sullivan C, Morin P, Lee HS, Kubilus CA, Daneshvar DH, Wulff M, Budson AE. TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy. J Neuropathol Exp Neurol. 2010 Sep; 69(9):918-29.View Related Profiles.

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Carreras I, Yuruker S, Aytan N, Hossain L, Choi JK, Jenkins BG, Kowall NW, Dedeoglu A. Moderate exercise delays the motor performance decline in a transgenic model of ALS. Brain Res. 2010 Feb 8; 1313:192-201.View Related Profiles.

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Choi JK, Jenkins BG, Carreras I, Kaymakcalan S, Cormier K, Kowall NW, Dedeoglu A. Anti-inflammatory treatment in AD mice protects against neuronal pathology. Exp Neurol. 2010 Jun; 223(2):377-84.View Related Profiles.

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Lee J, Ryu H, Kowall NW. Differential regulation of neuronal and inducible nitric oxide synthase (NOS) in the spinal cord of mutant SOD1 (G93A) ALS mice. Biochem Biophys Res Commun. 2009 Sep 11; 387(1):202-6.View Related Profiles.

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Lee J, Ryu H, Kowall NW. Motor neuronal protection by L-arginine prolongs survival of mutant SOD1 (G93A) ALS mice. Biochem Biophys Res Commun. 2009 Jul 10; 384(4):524-9.View Related Profiles.

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Aydin C, Aytan N, Mahon MJ, Tawfeek HA, Kowall NW, Dedeoglu A, Bastepe M. Extralarge XL(alpha)s (XXL(alpha)s), a variant of stimulatory G protein alpha-subunit (Gs(alpha)), is a distinct, membrane-anchored GNAS product that can mimic Gs(alpha). Endocrinology. 2009 Aug; 150(8):3567-75.View Related Profiles.

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Lee J, Kannagi M, Ferrante RJ, Kowall NW, Ryu H. Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis. FASEB J. 2009 Jun; 23(6):1739-49.View Related Profiles.

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Yaar M, Arble BL, Stewart KB, Qureshi NH, Kowall NW, Gilchrest BA. p75NTR antagonistic cyclic peptide decreases the size of beta amyloid-induced brain inflammation. Cell Mol Neurobiol. 2008 Dec; 28(8):1027-31.View Related Profiles.

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Vlad SC, Miller DR, Kowall NW, Felson DT. Protective effects of NSAIDs on the development of Alzheimer disease. Neurology. 2008 May 6; 70(19):1672-7.View Related Profiles.

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Harper DG, Stopa EG, Kuo-Leblanc V, McKee AC, Asayama K, Volicer L, Kowall N, Satlin A. Dorsomedial SCN neuronal subpopulations subserve different functions in human dementia. Brain. 2008 Jun; 131(Pt 6):1609-17.View Related Profiles.

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McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res. 2008 May 1; 1207:225-36.View Related Profiles.

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Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ. Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice. J Neurosci. 2007 Nov 21; 27(47):12908-15.View Related Profiles.

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Mellott TJ, Kowall NW, Lopez-Coviella I, Blusztajn JK. Prenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats. Brain Res. 2007 Jun 2; 1151:1-11.View Related Profiles.

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Lee J, Kosaras B, Aleyasin H, Han JA, Park DS, Ratan RR, Kowall NW, Ferrante RJ, Lee SW, Ryu H. Role of cyclooxygenase-2 induction by transcription factor Sp1 and Sp3 in neuronal oxidative and DNA damage response. FASEB J. 2006 Nov; 20(13):2375-7.View Related Profiles.

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McKee AC, Au R, Cabral HJ, Kowall NW, Seshadri S, Kubilus CA, Drake J, Wolf PA. Visual association pathology in preclinical Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jun; 65(6):621-30.View Related Profiles.

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Kraytsberg Y, Kudryavtseva E, McKee AC, Geula C, Kowall NW, Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nat Genet. 2006 May; 38(5):518-20.View Related Profiles.

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Klivenyi P, Siwek D, Gardian G, Yang L, Starkov A, Cleren C, Ferrante RJ, Kowall NW, Abeliovich A, Beal MF. Mice lacking alpha-synuclein are resistant to mitochondrial toxins. Neurobiol Dis. 2006 Mar; 21(3):541-8. PMID: 16298531

Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Exp Gerontol. 2004 Nov-Dec; 39(11-12):1641-9.View Related Profiles.

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Dedeoglu A, Choi JK, Cormier K, Kowall NW, Jenkins BG. Magnetic resonance spectroscopic analysis of Alzheimer's disease mouse brain that express mutant human APP shows altered neurochemical profile. Brain Res. 2004 Jun 25; 1012(1-2):60-5.View Related Profiles.

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Sheridan PL, Solomont J, Kowall N, Hausdorff JM. Influence of executive function on locomotor function: divided attention increases gait variability in Alzheimer's disease. J Am Geriatr Soc. 2003 Nov; 51(11):1633-7. PMID: 14687395

Ferrante RJ, Kubilus JK, Lee J, Ryu H, Beesen A, Zucker B, Smith K, Kowall NW, Ratan RR, Luthi-Carter R, Hersch SM. Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's disease mice. J Neurosci. 2003 Oct 15; 23(28):9418-27.View Related Profiles.

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McKeon-O'Malley C, Siwek D, Lamoureux JA, Williams CL, Kowall NW. Prenatal choline deficiency decreases the cross-sectional area of cholinergic neurons in the medial septal nucleus. Brain Res. 2003 Jul 11; 977(2):278-83. PMID: 12834888

Albright CD, Siwek DF, Craciunescu CN, Mar MH, Kowall NW, Williams CL, Zeisel SH. Choline availability during embryonic development alters the localization of calretinin in developing and aging mouse hippocampus. Nutr Neurosci. 2003 Apr; 6(2):129-34. PMID: 12722989

Dedeoglu A, Kubilus JK, Jeitner TM, Matson SA, Bogdanov M, Kowall NW, Matson WR, Cooper AJ, Ratan RR, Beal MF, Hersch SM, Ferrante RJ. Therapeutic effects of cystamine in a murine model of Huntington's disease. J Neurosci. 2002 Oct 15; 22(20):8942-50.View Related Profiles.

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Kiechle T, Dedeoglu A, Kubilus J, Kowall NW, Beal MF, Friedlander RM, Hersch SM, Ferrante RJ. Cytochrome C and caspase-9 expression in Huntington's disease. Neuromolecular Med. 2002; 1(3):183-95.View Related Profiles.

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Malin DH, Crothers MK, Lake JR, Goyarzu P, Plotner RE, Garcia SA, Spell SH, Tomsic BJ, Giordano T, Kowall NW. Hippocampal injections of amyloid beta-peptide 1-40 impair subsequent one-trial/day reward learning. Neurobiol Learn Mem. 2001 Sep; 76(2):125-37. PMID: 11502145

Andreassen OA, Ferrante RJ, Klivenyi P, Klein AM, Dedeoglu A, Albers DS, Kowall NW, Beal MF. Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid. Exp Neurol. 2001 Apr; 168(2):356-63.View Related Profiles.

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Montine TJ, Shinobu L, Montine KS, Roberts LJ, Kowall NW, Beal MF, Morrow JD. No difference in plasma or urinary F2-isoprostanes among patients with Huntington's disease or Alzheimer's disease and controls. Ann Neurol. 2000 Dec; 48(6):950. PMID: 11117557

Simon DK, Mayeux R, Marder K, Kowall NW, Beal MF, Johns DR. Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology. 2000 Feb 8; 54(3):703-9. PMID: 10680807

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Shefner JM, Reaume AG, Flood DG, Scott RW, Kowall NW, Ferrante RJ, Siwek DF, Upton-Rice M, Brown RH. Mice lacking cytosolic copper/zinc superoxide dismutase display a distinctive motor axonopathy. Neurology. 1999 Oct 12; 53(6):1239-46. PMID: 10522879

Volicer L, Wells JM, McKee AC, Kowall NW. Enhanced inhibition of free radical-induced deoxyribose breakdown by Alzheimer brain homogenates. Neurosci Lett. 1999 Aug 6; 270(3):169-72.View Related Profiles.

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Kowall, Neil

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Hanlon EB, Itzkan I, Dasari RR, Feld MS, Ferrante RJ, McKee AC, Lathi D, Kowall NW. Near-infrared fluorescence spectroscopy detects Alzheimer's disease in vitro. Photochem Photobiol. 1999 Aug; 70(2):236-42.View Related Profiles.

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Kowall, Neil

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Klein AM, Kowall NW, Ferrante RJ. Neurotoxicity and oxidative damage of beta amyloid 1-42 versus beta amyloid 1-40 in the mouse cerebral cortex. Ann N Y Acad Sci. 1999; 893:314-20. PMID: 10672257

Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, Perry G. Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine. J Histochem Cytochem. 1998 Jun; 46(6):731-5. PMID: 9603784

McKee AC, Kowall NW, Schumacher JS, Beal MF. The neurotoxicity of amyloid beta protein in aged primates. Amyloid. 1998 Mar; 5(1):1-9.View Related Profiles.

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Kowall, Neil

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Kowall NW, Ferrante RJ. The Neuropathology of Huntington’s Disease. In: Neuropathology of Neurodegenerative diseases. Ed. W Markesberry. 1998.

Ferrante RJ, Browne SE, Shinobu LA, Bowling AC, Baik MJ, MacGarvey U, Kowall NW, Brown RH, Beal MF. Evidence of increased oxidative damage in both sporadic and familial amyotrophic lateral sclerosis. J Neurochem. 1997 Nov; 69(5):2064-74. PMID: 9349552

Beal MF, Ferrante RJ, Browne SE, Matthews RT, Kowall NW, Brown RH. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol. 1997 Oct; 42(4):644-54. PMID: 9382477

Ferrante RJ, Shinobu LA, Schulz JB, Matthews RT, Thomas CE, Kowall NW, Gurney ME, Beal MF. Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation. Ann Neurol. 1997 Sep; 42(3):326-34. PMID: 9307254

Ferrante RJ, Gutekunst CA, Persichetti F, McNeil SM, Kowall NW, Gusella JF, MacDonald ME, Beal MF, Hersch SM. Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum. J Neurosci. 1997 May 1; 17(9):3052-63. PMID: 9096140

Ferrante RJ, Schulz JB, Kowall NW, Beal MF. Systemic administration of rotenone produces selective damage in the striatum and globus pallidus, but not in the substantia nigra. Brain Res. 1997 Apr 4; 753(1):157-62. PMID: 9125443

Ferrante RJ, Brouillet E, Hantraye P, Kowall NW, Bea, MF. Mitochondrial Dysfunction as a Model for Huntington's Disease Using the Electron Transport Chain Inhibitor, 3-Nitropropionic Acid. In: Neurodegenerative Diseases: Mitochondria and Free Radicals in Pathogenesis. eds. M. Flint. Beal, Ivan BodisWollner, and Neil Howell. 1997; 229-244.

Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N. Oxidative damage in Alzheimer's. Nature. 1996 Jul 11; 382(6587):120-1. PMID: 8700201

Speliotes EK, Caday CG, Do T, Weise J, Kowall NW, Finklestein SP. Increased expression of basic fibroblast growth factor (bFGF) following focal cerebral infarction in the rat. Brain Res Mol Brain Res. 1996 Jul; 39(1-2):31-42. PMID: 8804711

Reaume AG, Elliott JL, Hoffman EK, Kowall NW, Ferrante RJ, Siwek DF, Wilcox HM, Flood DG, Beal MF, Brown RH, Scott RW, Snider WD. Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury. Nat Genet. 1996 May; 13(1):43-7. PMID: 8673102

De Gasperi R, Angel M, Sosa G, Patarca R, Battistini S, Lamoreux MR, Raghavan S, Kowall NW, Smith KH, Fletcher MA, Kolodny EH. Intrathecal synthesis of anti-sulfatide IgG is associated with peripheral nerve disease in acquired immunodeficiency syndrome. AIDS Res Hum Retroviruses. 1996 Feb 10; 12(3):205-11. PMID: 8835198

Speliotes EK, Kowall NW, Shanti BF, Kosofsky B, Finklestein SP, Leifer D. Myocyte-specific enhancer binding factor 2C expression in gerbil brain following global cerebral ischemia. Neuroscience. 1996 Jan; 70(1):67-77. PMID: 8848137

Farrer LA, Abraham CR, Volicer L, Foley EJ, Kowall NW, McKee AC, Wells JM. Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Exp Neurol. 1995 Dec; 136(2):162-70.View Related Profiles.

McKee, Ann
Abraham, Carmela
Farrer, Lindsay
Kowall, Neil

PMID: 7498406

Schulz JB, Matthews RT, Jenkins BG, Ferrante RJ, Siwek D, Henshaw DR, Cipolloni PB, Mecocci P, Kowall NW, Rosen BR, et al. Blockade of neuronal nitric oxide synthase protects against excitotoxicity in vivo. J Neurosci. 1995 Dec; 15(12):8419-29. PMID: 8613773

Beal MF, Ferrante RJ, Henshaw R, Matthews RT, Chan PH, Kowall NW, Epstein CJ, Schulz JB. 3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice. J Neurochem. 1995 Aug; 65(2):919-22. PMID: 7616254

Brouillet E, Hantraye P, Ferrante RJ, Dolan R, Leroy-Willig A, Kowall NW, Beal MF. Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates. Proc Natl Acad Sci U S A. 1995 Jul 18; 92(15):7105-9. PMID: 7624378; PMCID: PMC41480

Matsumoto K, Lo EH, Pierce AR, Wei H, Garrido L, Kowall NW. Role of vasogenic edema and tissue cavitation in ischemic evolution on diffusion-weighted imaging: comparison with multiparameter MR and immunohistochemistry. AJNR Am J Neuroradiol. 1995 May; 16(5):1107-15. PMID: 7639135

Schulz JB, Henshaw DR, Siwek D, Jenkins BG, Ferrante RJ, Cipolloni PB, Kowall NW, Rosen BR, Beal MF. Involvement of free radicals in excitotoxicity in vivo. J Neurochem. 1995 May; 64(5):2239-47. PMID: 7536809

Kowall NW. How tight is the connection between synapse loss and clinical dementia? Neurobiol Aging. 1995; 16:300-302.

Schwagerl AL, Mohan PS, Cataldo AM, Vonsattel JP, Kowall NW, Nixon RA. Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease. J Neurochem. 1995 Jan; 64(1):443-6. PMID: 7798944

Leifer D, Golden J, Kowall NW. Myocyte-specific enhancer binding factor 2C expression in human brain development. Neuroscience. 1994 Dec; 63(4):1067-79. PMID: 7700509

Schulz JB, Henshaw DR, Jenkins BG, Ferrante RJ, Kowall NW, Rosen BR, Beal MF. 3-Acetylpyridine produces age-dependent excitotoxic lesions in rat striatum. J Cereb Blood Flow Metab. 1994 Nov; 14(6):1024-9. PMID: 7929644

Boviatsis EJ, Scharf JM, Chase M, Harrington K, Kowall NW, Breakefield XO, Chiocca EA. Antitumor activity and reporter gene transfer into rat brain neoplasms inoculated with herpes simplex virus vectors defective in thymidine kinase or ribonucleotide reductase. Gene Ther. 1994 Sep; 1(5):323-31. PMID: 7584098

Volicer L, Hurley AC, Lathi DC, Kowall NW. Measurement of severity in advanced Alzheimer's disease. J Gerontol. 1994 Sep; 49(5):M223-6. PMID: 8056941

Wei MX, Tamiya T, Chase M, Boviatsis EJ, Chang TK, Kowall NW, Hochberg FH, Waxman DJ, Breakefield XO, Chiocca EA. Experimental tumor therapy in mice using the cyclophosphamide-activating cytochrome P450 2B1 gene. Hum Gene Ther. 1994 Aug; 5(8):969-78.View Related Profiles.

Waxman, David
Kowall, Neil

PMID: 7948146

Storey E, Cipolloni PB, Ferrante RJ, Kowall NW, Beal MF. Movement disorder following excitotoxin lesions in primates. Neuroreport. 1994 Jun 2; 5(10):1259-61. PMID: 7919178

Rosen DR, Bowling AC, Patterson D, Usdin TB, Sapp P, Mezey E, McKenna-Yasek D, O'Regan J, Rahmani Z, Ferrante RJ, et al. A frequent ala 4 to val superoxide dismutase-1 mutation is associated with a rapidly progressive familial amyotrophic lateral sclerosis. Hum Mol Genet. 1994 Jun; 3(6):981-7. PMID: 7951249

Henshaw R, Jenkins BG, Schulz JB, Ferrante RJ, Kowall NW, Rosen BR, Beal MF. Malonate produces striatal lesions by indirect NMDA receptor activation. Brain Res. 1994 May 30; 647(1):161-6. PMID: 8069700

Koketsu N, Berlove DJ, Moskowitz MA, Kowall NW, Caday CG, Finklestein SP. Pretreatment with intraventricular basic fibroblast growth factor decreases infarct size following focal cerebral ischemia in rats. Ann Neurol. 1994 Apr; 35(4):451-7. PMID: 8154872

Kowall NW. Beta amyloid neurotoxicity and neuronal degeneration in Alzheimer's disease. Neurobiol Aging. 1994 Mar-Apr; 15(2):257-8. PMID: 7838305

Boviatsis EJ, Chase M, Wei MX, Tamiya T, Hurford RK, Kowall NW, Tepper RI, Breakefield XO, Chiocca EA. Gene transfer into experimental brain tumors mediated by adenovirus, herpes simplex virus, and retrovirus vectors. Hum Gene Ther. 1994 Feb; 5(2):183-91. PMID: 8186298

Giordano T, Pan JB, Monteggia LM, Holzman TF, Snyder SW, Krafft G, Ghanbari H, Kowall NW. Similarities between beta amyloid peptides 1-40 and 40-1: effects on aggregation, toxicity in vitro, and injection in young and aged rats. Exp Neurol. 1994 Feb; 125(2):175-82. PMID: 8313936

Ferrante RJ, Kowall NW, Richardson EP Jr. Neuronal plasticity: a potential role in spiny striatal neuron degeneration in Huntington's disease. In: K Fuxe, LF Agnati, B Bjelke, D Ottoson ed. Trophic Regulation of the Basal Ganglia - focus on dopamine neurons. 1994; 465-477.

Lo EH, Pan Y, Matsumoto K, Kowall NW. Blood-brain barrier disruption in experimental focal ischemia: comparison between in vivo MRI and immunocytochemistry. Magn Reson Imaging. 1994; 12(3):403-11. PMID: 8007769

Lathi DC, Kemper T, Rosalis R, Mahasaen C, Kowall NW . A quantitative regional analysis of vascular amyloidosis in Alzheimer's disease. Proc VII Intl Symp on Amyloidosis. 1994.
Ferrante RJ, Beal MF, Kowall NW. Mechanisms of neuronal degeneration in Huntington's disease. In: G Percheron JS McKenzie and J. Feger ed. The Basal Ganglia IV: New Ideas and Data on Structure and Function. Plenum Press. New York. 1994; 149-161.

Leifer D, Kowall NW. Immunohistochemical patterns of selective cellular vulnerability in human cerebral ischemia. J Neurol Sci. 1993 Nov; 119(2):217-28. PMID: 8277338

Beal MF, Brouillet E, Jenkins BG, Ferrante RJ, Kowall NW, Miller JM, Storey E, Srivastava R, Rosen BR, Hyman BT. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J Neurosci. 1993 Oct; 13(10):4181-92. PMID: 7692009

Nihei K, Kowall NW. Involvement of NPY-immunoreactive neurons in the cerebral cortex of amyotrophic lateral sclerosis patients. Neurosci Lett. 1993 Sep 3; 159(1-2):67-70. PMID: 8264981

Kowall NW, Quigley BJ, Krause JE, Lu F, Kosofsky BE, Ferrante RJ. Substance P and substance P receptor histochemistry in human neurodegenerative diseases. Regul Pept. 1993 Jul 2; 46(1-2):174-85. PMID: 7692486

Markesbery WR, Wang HZ, Kowall NW, Kosik KS, McKee AC. Morphometric image analysis of neuropil threads in Alzheimer's disease. Neurobiol Aging. 1993 Jul-Aug; 14(4):303-7.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 8367011

Nihei K, McKee AC, Kowall NW. Patterns of neuronal degeneration in the motor cortex of amyotrophic lateral sclerosis patients. Acta Neuropathol. 1993; 86(1):55-64.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 8396837

Kowall NW , McKee AC. The histopathology of neuronal degeneration and plasticity in Alzheimer's disease. In: Neural Regeneration, ed. F.J. Seil Advances in Neurology. Raven Press. New York,NY. 1993; 59:5-33.

Brouillet E, Jenkins BG, Hyman BT, Ferrante RJ, Kowall NW, Srivastava R, Roy DS, Rosen BR, Beal MF. Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid. J Neurochem. 1993 Jan; 60(1):356-9. PMID: 8417157

Kowall NW, McKee AC. The histopathology of neuronal degeneration and plasticity in Alzheimer disease. Adv Neurol. 1993; 59:5-33.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 8420123

Ferrante RJ, Kowall NW, Cipolloni PB, Storey E, Beal MF. Excitotoxin lesions in primates as a model for Huntington's disease: histopathologic and neurochemical characterization. Exp Neurol. 1993 Jan; 119(1):46-71. PMID: 8432351

Storey E, Kowall NW, Finn SF, Mazurek MF, Beal MF. The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex. Ann Neurol. 1992 Oct; 32(4):526-34. PMID: 1280937

Kowall NW, McKee AC, Yankner BA, Beal MF. In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment. Neurobiol Aging. 1992 Sep-Oct; 13(5):537-42.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 1461341

Yokota M, Peterson JW, Kaoutzanis M, Kowall NW. Immunohistochemical distribution of protein kinase C isozymes is differentially altered in ischemic gerbil hippocampus. Brain Res. 1992 Jul 31; 587(1):123-9. PMID: 1525642

deVeber GA, Schwarting GA, Kolodny EH, Kowall NW. Fabry disease: immunocytochemical characterization of neuronal involvement. Ann Neurol. 1992 Apr; 31(4):409-15. PMID: 1375013

Leifer D, Kowall NW. Thy-1 in hippocampus: normal anatomy and neuritic growth in Alzheimer's disease. J Neuropathol Exp Neurol. 1992 Mar; 51(2):133-41. PMID: 1347079

Nihei K, Kowall NW. Neurofilament and neural cell adhesion molecule immunocytochemistry of Huntington's disease striatum. Ann Neurol. 1992 Jan; 31(1):59-63. PMID: 1531909

Kowall NW. Primitive Reflexes. In: Disorders of Movement in Psychiatry and Neurology, ed. Joseph AB and Young RR. Blackwell. London. 1992; 699-703.
Lee JM, Weinstein DA, Kowall NW, Beal MF . Inability of ß-amyloid (ß(25-35)) to bind to central nervous system neurokinin 1 receptors. Drug Dev Res. 1992; 27:441-444.

Ferrante RJ, Kowall NW, Richardson EP. Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry. J Neurosci. 1991 Dec; 11(12):3877-87. PMID: 1836019

Wang LN, Kowall NW, Richardson EP. Phosphorylated neurofilament epitopes in the achromasic neurons of corticonigral degeneration. Chin Med J (Engl). 1991 Dec; 104(12):1011-7. PMID: 1782810

Kowall NW, Beal MF, Busciglio J, Duffy LK, Yankner BA. An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):7247-51. PMID: 1714596; PMCID: PMC52271

McKee AC, Kosik KS, Kowall NW. Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol. 1991 Aug; 30(2):156-65.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 1910274

Uemura Y, Kowall NW, Moskowitz MA. Focal ischemia in rats causes time-dependent expression of c-fos protein immunoreactivity in widespread regions of ipsilateral cortex. Brain Res. 1991 Jun 21; 552(1):99-105. PMID: 1913186

Leifer D, Cole DG, Kowall NW. Neuropathologic asymmetries in the brain of a patient with a unilateral status epilepticus. J Neurol Sci. 1991 Jun; 103(2):127-35. PMID: 1715386

Beal MF, Ferrante RJ, Swartz KJ, Kowall NW. Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci. 1991 Jun; 11(6):1649-59. PMID: 1710657

Uemura Y, Kowall NW, Beal MF. Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus. Brain Res. 1991 Mar 1; 542(2):343-7. PMID: 1827611

Kowall NW, Beal MF. Glutamate-, glutaminase-, and taurine-immunoreactive neurons develop neurofibrillary tangles in Alzheimer's disease. Ann Neurol. 1991 Feb; 29(2):162-7. PMID: 1672808

Beal MF, Swartz KJ, Finn SF, Mazurek MF, Kowall NW. Neurochemical characterization of excitotoxin lesions in the cerebral cortex. J Neurosci. 1991 Jan; 11(1):147-58. PMID: 1670782

Quigley BJ, Kowall NW. Substance P-like immunoreactive neurons are depleted in Alzheimer's disease cerebral cortex. Neuroscience. 1991; 41(1):41-60. PMID: 1711654

Sangruchi T, Kowall NW. NADPH diaphorase histochemistry of the human hypothalamus. Neuroscience. 1991; 40(3):713-24. PMID: 2062439

Kowall NW , Kosik KS. Histochemical observations on neuronal degeneration, cytoskeletal reorganization and phosphorylation in Alzheimer's disease. Proceedings of the XIth Intl Congress of Neuropathology. 1991; 105-109.

Uemura Y, Kowall NW, Beal MF. Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum. Ann Neurol. 1990 Jun; 27(6):620-5. PMID: 1972876

McKee AC, Levine DN, Kowall NW, Richardson EP. Peduncular hallucinosis associated with isolated infarction of the substantia nigra pars reticulata. Ann Neurol. 1990 May; 27(5):500-4.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 2360791

Thulborn KR, Sorensen AG, Kowall NW, McKee A, Lai A, McKinstry RC, Moore J, Rosen BR, Brady TJ. The role of ferritin and hemosiderin in the MR appearance of cerebral hemorrhage: a histopathologic biochemical study in rats. AJR Am J Roentgenol. 1990 May; 154(5):1053-9. PMID: 2108542

Thulborn KR, Sorensen AG, Kowall NW, McKee A, Lai A, McKinstry RC, Moore J, Rosen BR, Brady TJ. The role of ferritin and hemosiderin in the MR appearance of cerebral hemorrhage: a histopathologic biochemical study in rats. AJNR Am J Neuroradiol. 1990 Mar-Apr; 11(2):291-7. PMID: 1690500

Cudkowicz M, Kowall NW. Degeneration of pyramidal projection neurons in Huntington's disease cortex. Ann Neurol. 1990 Feb; 27(2):200-4. PMID: 2138444

McKee AC, Kosik KS, Kennedy MB, Kowall NW. Hippocampal neurons predisposed to neurofibrillary tangle formation are enriched in type II calcium/calmodulin-dependent protein kinase. J Neuropathol Exp Neurol. 1990 Jan; 49(1):49-63.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 2153760

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ. Homocysteic acid lesions in rat striatum spare somatostatin-neuropeptide Y (NADPH-diaphorase) neurons. Neurosci Lett. 1990 Jan 1; 108(1-2):36-42. PMID: 1689475

Kostyk SK, Kowall NW, Hauser SL. Substance P immunoreactive astrocytes are present in multiple sclerosis plaques. Brain Res. 1989 Dec 18; 504(2):284-8. PMID: 2480834

Kelley M, Kowall N. Corticotropin-releasing factor immunoreactive neurons persist throughout the brain in Alzheimer's disease. Brain Res. 1989 Nov 6; 501(2):392-6. PMID: 2819447

McKee AC, Kowall NW, Kosik KS. Microtubular reorganization and dendritic growth response in Alzheimer's disease. Ann Neurol. 1989 Nov; 26(5):652-9.View Related Profiles.

McKee, Ann
Kowall, Neil

PMID: 2817839

Kowall NW, Beal MF. Galanin-like immunoreactivity is present in human substantia innominata and in senile plaques in Alzheimer's disease. Neurosci Lett. 1989 Mar 13; 98(1):118-23. PMID: 2469045

Kosik KS, Kowall NW, McKee A. Along the way to a neurofibrillary tangle: a look at the structure of tau. Ann Med. 1989; 21(2):109-12. PMID: 2504256

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Differential sparing of somatostatin-neuropeptide Y and cholinergic neurons following striatal excitotoxin lesions. Synapse. 1989; 3(1):38-47. PMID: 2563916

Beal MF, Mazurek MF, Ellison DW, Kowall NW, Solomon PR, Pendlebury WW. Neurochemical characteristics of aluminum-induced neurofibrillary degeneration in rabbits. Neuroscience. 1989; 29(2):339-46. PMID: 2566953

Kowall NW, Pendlebury WW, Kessler JB, Perl DP, Beal MF. Aluminum-induced neurofibrillary degeneration affects a subset of neurons in rabbit cerebral cortex, basal forebrain and upper brainstem. Neuroscience. 1989; 29(2):329-37. PMID: 2725861

Martin JB, Beal MF, Kowall NW, Mazurek MF. Alterations of neuropeptide Y in neurological disorders. In: Neuropeptide Y, Karolinska Institute Nobel Conference Series, ed. Mutt V, Hokflet T, Fuxe K, and Lundberg JM. Raven Press. New York,NY. 1989; 313-320.

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Systemic approaches to modifying quinolinic acid striatal lesions in rats. J Neurosci. 1988 Oct; 8(10):3901-8. PMID: 2461437

Kowall NW, Mueller MP. Morphology and distribution of nicotinamide adenine dinucleotide phosphate (reduced form) diaphorase reactive neurons in human brainstem. Neuroscience. 1988 Aug; 26(2):645-54. PMID: 3173692

Beal MF, Kowall NW, Swartz KJ, Ferrante RJ, Martin JB. Response:Model of Huntington's disease. Science. 1988 Jul 22; 241(4864):475. PMID: 17792612

Kowall NW, Beal MF. Cortical somatostatin, neuropeptide Y, and NADPH diaphorase neurons: normal anatomy and alterations in Alzheimer's disease. Ann Neurol. 1988 Feb; 23(2):105-14. PMID: 2897822

Pendlebury WW, Beal MF, Kowall NW, Solomon PR. Neuropathologic, neurochemical and immunocytochemical characteristics of aluminum-induced neurofilamentous degeneration. Neurotoxicology. 1988; 9(3):503-10. PMID: 3200512

Kowall NW, Mueller MG . Topography of NADPH diaphorase neurons in human brainstem. Neuroscience. 1988; 26:645-654.
Kowall NW, Sobel RA. Case Records of the Massachusetts General Hospital (Case 7-88). NEJM. 1988; 318:427-440.
Martin JB, Beal MF, Mazurek MF, Kowall NW, Growdon JH. Some observations on the significance of neurotransmitter changes in Alzheimer Disease. In: Aging and the Brain, ed. Terry RD. Raven. New York,NY. 1988; 32:129-148.

Kowall NW, Kosik KS. Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease. Ann Neurol. 1987 Nov; 22(5):639-43. PMID: 3122646

Ferrante RJ, Kowall NW. Tyrosine hydroxylase-like immunoreactivity is distributed in the matrix compartment of normal human and Huntington's disease striatum. Brain Res. 1987 Jul 21; 416(1):141-6. PMID: 2887244

Ellison DW, Kowall NW, Martin JB. Subset of neurons characterized by the presence of NADPH-diaphorase in human substantia innominata. J Comp Neurol. 1987 Jun 8; 260(2):233-45. PMID: 3611405

Ferrante RJ, Beal MF, Kowall NW, Richardson EP, Martin JB. Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease. Brain Res. 1987 May 12; 411(1):162-6. PMID: 2955849

Kowall NW, Ferrante RJ, Beal MF, Richardson EP, Sofroniew MV, Cuello AC, Martin JB. Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: a combined immunocytochemical and enzyme histochemical study. Neuroscience. 1987 Mar; 20(3):817-28. PMID: 2885780

Kowall NW, Ferrante RJ, Martin JB. Patterns of cell loss in Huntington's disease. Trends in Neurosciences. 1987; 10:24-29.

Ferrante RJ, Kowall NW, Beal MF, Martin JB, Bird ED, Richardson EP. Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease. J Neuropathol Exp Neurol. 1987 Jan; 46(1):12-27. PMID: 2947977

Kowall NW, Ferrante RJ, Martin JB. Neuropathology of Huntington's disease-reply. Trends in Neurosciences. 1987; 10:404-406.

Kosik KS, Rogers J, Kowall NW. Senile plaques are located between apical dendritic clusters. J Neuropathol Exp Neurol. 1987 Jan; 46(1):1-11. PMID: 3794758

Pendlebury WW, Beal MF, Kowall NW, Solomon PR. Results of immunocytochemical, neurochemical, and behavioral studies in aluminum-induced neurofilamentous degeneration. J Neural Transm Suppl. 1987; 24:213-7. PMID: 3479524

Beal MF, Kowall NW, Mazurek MF. Neuropeptides in Alzheimer's disease. J Neural Transm Suppl. 1987; 24:163-74. PMID: 2445913

Ferrante RJ, Kowall NW, Richardson EP, Bird ED, Martin JB. Topography of enkephalin, substance P and acetylcholinesterase staining in Huntington's disease striatum. Neurosci Lett. 1986 Nov 21; 71(3):283-8. PMID: 2432445

Haber SN, Kowall NW, Vonsattel JP, Bird ED, Richardson EP. Gilles de la Tourette's syndrome. A postmortem neuropathological and immunohistochemical study. J Neurol Sci. 1986 Sep; 75(2):225-41. PMID: 2428943

Groenewegen HJ, Ahlenius S, Haber SN, Kowall NW, Nauta WJ. Cytoarchitecture, fiber connections, and some histochemical aspects of the interpeduncular nucleus in the rat. J Comp Neurol. 1986 Jul 1; 249(1):65-102. PMID: 2426312

Beal MF, Kowall NW, Ellison DW, Mazurek MF, Swartz KJ, Martin JB. Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature. 1986 May 8-14; 321(6066):168-71. PMID: 2422561

Beal MF, Uhl G, Mazurek MF, Kowall N, Martin JB. Somatostatin: alterations in the central nervous system in neurological diseases. Res Publ Assoc Res Nerv Ment Dis. 1986; 64:215-57. PMID: 2873636

Ferrante RJ, Kowall NW, Beal MF, Richardson EP, Bird ED, Martin JB. Selective sparing of a class of striatal neurons in Huntington's disease. Science. 1985 Nov 1; 230(4725):561-3. PMID: 2931802

Kowall NW, Beal MF, Ferrante RJ, Martin JB. Topography of nicotinamide adenine dinucleotide phosphate-diaphorase staining neurons in rat striatum. Neurosci Lett. 1985 Aug 16; 59(1):61-6. PMID: 2931630

Kowall N, Stansbury R, Charman H, Gardner M. A current look at feline lymphoma. Vet Clin North Am. 1971 May; 1(2):355-65. PMID: 4347118

Martin JB, Kowall NW, Ferrante RJ. Striatal degeneration and neuronal sparing in Huntington's disease, Butterworths.
Martin JB, Ferrante RJ, Kowall NW. Individual cell types as targets of neural disease processes in Huntington's disease. In: Molecular Biology of the Human Brain, ed. Jones EG . UCLA symposium. Alan R. Liss. New York,NY. 72.

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 242 publications over 37 distinct years, with a maximum of 16 publications in 1994 and 2013

Bar chart showing 242 publications over 37 distinct years, with a maximum of 16 publications in 1994 and 2013

Year	Publications
1985	2
1986	5
1987	11
1988	8
1989	9
1990	7
1991	13
1992	8
1993	10
1994	16
1995	8
1996	5
1997	6
1998	3
1999	5
2000	3
2001	2
2002	2
2003	4
2004	2
2005	1
2006	3
2007	2
2008	5
2009	6
2010	4
2011	6
2012	9
2013	16
2014	8
2015	5
2016	4
2017	12
2018	11
2019	10
2020	10
2021	1

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