Manju L. Subramanian, MD
Associate Professor
Boston University Chobanian & Avedisian School of Medicine
Ophthalmology

MD, University of Missouri School of Medicine
BS, University of Missouri



Manju Subramanian is an Associate Professor at Boston University and Vice-Chair of Faculty Affairs in the Department of Ophthalmology. She is an ophthalmic surgeon specializing in vitreoretinal disease and surgery and is in academic practice at Boston Medical Center. Her primary areas of clinical interest include medical and surgical management of diabetic retinopathy, age-related macular degeneration, retinal detachments, hereditary retinal diseases, ocular inflammation, and ocular trauma. Dr. Subramanian graduated from the University of Missouri School of Medicine and completed her residency at the University of Kansas Medical Center. She completed a fellowship in Vitreoretinal Disease and Surgery at Tufts University School of Medicine and Ophthalmic Consultants of Boston.

Dr. Subramanian's research interests include the study of eye fluid biomarkers as a potential diagnostic modality in Alzheimer's Disease (AD). She is also active in clinical outcomes research in eye diseases such as age-related macular degeneration, diabetic retinopathy, and the role of anesthesia in eye surgery, with a particular emphasis on health disparities. She was Principal Investigator for a VA Boston sponsored head-to-head clinical trial comparing bevacizumab and ranibizumab in the treatment of age-related macular degeneration, and she was Principal Investigator for a study assessing the role of oral sedation in eye surgery. She is also a recipient of an R03 Grant Award by the National Institutes of Aging, in 2019, as the Principal Investigator of a study looking at protein biomarkers for AD in the eye.

In her leadership roles, she served as the Vice-Chair of Clinical Services within Ophthalmology for 8 years where she worked with hospital administrators in clinical operations, quality and compliance, and the creation of a new eye clinic. In 2017, she transitioned her role to Vice-Chair of Faculty Affairs where she currently supports the professional development and career engagement of the clinical faculty. She serves on several institutional committees, including the Boston University Medical Group (BUMG) Research Committee, the BU Chobanian and Avedisian School of Medicine Promotion Criteria Working Group, and she is the past Chair of the BUMG Professional Development Committee. She is also a voting member of the BUMG Board of Trustees. She additionally serves on national committees, such as RESOURCE Committe with the Retina Society and serves on several Special Emphasis Panel with the National Institutes of Health, and she is a past member of the International Meetings Committee for the American Academy of Ophthalmology (AAO) and the Diversity Initiatives Committee for Association for Research in Vision and Ophthalmology.

Diversity, Equity, Inclusion and Accessibility

Dr. Subramanian has contributed to diversity, equity and inclusion in several ways. First, she has spent her career caring for patients who have been displaced due to their socioeconomic status, immigration status, inability to speak English, food insecurity, homelessness, and addiction. Second, Dr. Subramanian's investigates racial and socioeconomic disparities in treatment outcomes in eye diseases, such as diabetic macular edema and retinal detachments, as well as the underrepresentation of racial and ethnic minorities in clinical trials for eye disease. And finally, Dr. Subramanian contributes on an institutional and national level by serving on the Gender Equity Advisory Council at Boston University Medical Center and was a past member of the Diversity Initiatives Committee with the Association for Research in Vision and Ophthalmology.



CLKA651X2202: A randomized, active-controlled, patient and investigator-masked, multiple dose proof-of-concept study of intravitreal LKA651 in patients with diabetic macular edema
04/30/2021 - 04/29/2024 (PI)
Novartis Pharma Corp

Eye to Brain: Eye Biomarkers and Cognition
04/15/2019 - 02/28/2023 (PI)
National Institute on Aging/NIH/DHHS
1R03AG063255-01


Title


Yr Title Project-Sub Proj Pubs
2020 Eye to Brain: Eye Biomarkers and Cognition 5R03AG063255-02
2019 Eye to Brain: Eye Biomarkers and Cognition 1R03AG063255-01

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Sampani K, Ness S, Tuz-Zahra F, Aytan N, Spurlock EE, Alluri S, Chen X, Siegel NH, Alosco ML, Xia W, Tripodis Y, Stein TD, Subramanian ML. Neurodegenerative biomarkers in different chambers of the eye relative to plasma: an agreement validation study. Alzheimers Res Ther. 2024 Aug 26; 16(1):192.View Related Profiles. PMID: 39187891; PMCID: PMC11346268; DOI: 10.1186/s13195-024-01556-y;
     
  2. Prasad M, Goodman D, Xu J, Gutta S, Zubieta D, Alluri S, Siegel NH, Peeler CE, Lee HJ, Cabral HJ, Subramanian ML. Long-Term Satisfaction of Oral Sedation versus Standard-of-Care Intravenous Sedation for Ocular Surgery. Clin Ophthalmol. 2024; 18:735-742.View Related Profiles. PMID: 38476357; PMCID: PMC10929550; DOI: 10.2147/OPTH.S444999;
     
  3. Dia M, Davoudi S, Sanayei N, Martin DC, Albrecht MM, Ness S, Subramanian M, Siegel N, Chen X. Demographic and socioeconomic disparities in the hybrid ophthalmology telemedicine model. J Telemed Telecare. 2023 Nov 13; 1357633X231211353.View Related Profiles. PMID: 37960873
     
  4. Bains A, Osathanugrah P, Sanjiv N, Chiu C, Fiorello MG, Siegel NH, Peeler CE, Distefano AG, Lee HJ, Ness S, Desai MA, Titelbaum JR, Pira T, LaMattina KC, Christiansen SP, Cabral HJ, Subramanian ML. Diverse Research Teams and Underrepresented Groups in Clinical Studies. JAMA Ophthalmol. 2023 Nov 01; 141(11):1037-1044.View Related Profiles. PMID: 37856135; PMCID: PMC10587823; DOI: 10.1001/jamaophthalmol.2023.4638;
     
  5. Prasad M, Kosowsky T, Chen X, Davoudi Moghaddam S, Ness S, Peeler C, Siegel NH, Subramanian ML. Unrelenting Vision Loss: The Virulence of Klebsiella pneumoniae. Cureus. 2023 Sep; 15(9):e44786.View Related Profiles. PMID: 37809162; PMCID: PMC10558182; DOI: 10.7759/cureus.44786;
     
  6. Dia M, Albrecht MM, Sanayei N, Cabral H, Martin DC, Subramanian ML, Ness S, Siegel NH, Desai M, Chen X. Patient Satisfaction with the Hybrid Telemedicine Model for Ophthalmology. Telemed J E Health. 2024 Feb; 30(2):499-508.View Related Profiles. PMID: 37651189
     
  7. Nguyen AH, Davoudi S, Dong K, Bains A, Ness S, Subramanian ML, Siegel NH, Chen X. Socioeconomic Disparities in Patients Receiving Intravitreal Injections for Age-Related Macular Degeneration Amid the COVID-19 Pandemic. J Vitreoretin Dis. 2023; 7(5):376-381.View Related Profiles. PMID: 37701269; PMCID: PMC10311364; DOI: 10.1177/24741264231173771;
     
  8. Zeng K, Cabral H, Ness S, Subramanian M, Siegel N, Chen X. Effect of Lens Status on Diabetic Vitreous Hemorrhage Resolution. J Vitreoretin Dis. 2023; 7(3):220-225.View Related Profiles. PMID: 37188215; PMCID: PMC10170618; DOI: 10.1177/24741264231163394;
     
  9. Hussain A, Sheikh Z, Subramanian M. The Eye as a Diagnostic Tool for Alzheimer's Disease. Life (Basel). 2023 Mar 08; 13(3). PMID: 36983883; PMCID: PMC10052959; DOI: 10.3390/life13030726;
     
  10. Hussain A, Sheikh Z, Subramanian M. The Eye as a Diagnostic Tool for Alzheimer's Disease. Life (Basel). 2023 Mar 08; 13(3). PMID: 36983883; PMCID: PMC10052959; DOI: 10.3390/life13030726;
     
Showing 10 of 74 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 73 publications over 23 distinct years, with a maximum of 10 publications in 2023

YearPublications
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20203
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202310
20242


Diversifying Research Staff Is Linked to Increase in Racially Diverse Clinical Trial Participants

HealthCity 11/4/2023

Diversity Among Research Staff Found to Increase Participation of Underrepresented Patients in Clinical Studies

ReachMD 10/23/2023

Diversity Boosts Participation of Marginalized Patients in Studies

The Mirage 10/20/2023

Racial, Ethnic Concordance Improves Ophthalmic Clinical Trial Enrollment

HCP 10/20/2023

Improving clinical trial diversity may start with staff: Boston Medical Center's new research

Becker's Hospital Review 10/19/2023

Diversity Among Research Staff Increases Participation of Under-Represented Patients in Clinical Studies

Psychreg 10/19/2023

Study: Correlation found between vitreous human biomarkers and Alzheimer’s disease

Ophthalmology Times 6/20/2023

Biomarkers in the Eye Linked to Alzheimer’s Disease

Inside Precision Medicine 6/19/2023

AMD linked to Covid infection risks

Optician 1/16/2023

Age-related macular degeneration reported to confer higher risk of severe SARS-CoV-2 infection

News Medical 1/3/2023

Diabetic Macular Edema Treatment Less Effective in Black Patients

HealthCity 11/24/2020

BU Researchers: Avastin For Diabetic Macular Edema Less Effective Among Blacks Than Whites

Managed Healthcare Executive 11/14/2020

Diabetic Macular Edema in Black Patients Less Responsive to Bevacizumab

MedScape 11/2/2020

Keeping an eye on neurodegeneration

DDN News 11/1/2020

Diabetic macular edema in Black patients less responsive to bevacizumab

MD Alert 10/30/2020

Biomarker in the Eye May Flag Neurodegeneration Risk

Medscape 10/7/2020

Promising Alzheimer’s Biomarker Detected In the Human Eye

Being Patient 9/29/2020

Doctors could one day diagnose Alzheimer’s with a simple eye exam

Digital Trends 9/23/2020

Biomarker indicating neurodegeneration identified in the eye

Medical Xpress 9/21/2020

Scientists Find Biomarker of Degenerative Diseases in the Eye

The Science Times 9/21/2020

Phoning It In: A Benefit When It Comes to Preoperative Evaluations

HealthCity 5/30/2019

Boston Medical Center Receives NIH Grant for Eye To Brain: Eye Biomarkers and Cognition

Optical Coherence Tomography News 4/23/2019

Routine Eye Exams Could Give Clues About Dementia Later in Life

Being Patient 3/19/2019

Preoperative Phone Visits for Cataract Patients Safe, Efficient

Physician's Briefing 2/25/2019

2023 Boston University Chobanian and Avedisian School of Medicine : Distinguished Faculty of the Month - October 2023
2023 American Academy of Ophthalmology: Achievement Award
2022 American Society of Retina Specialists: Honor Award
2016 Ocular Surgery News: OSN 150 Top Retina Specialists
2006 Boston University Chobanian and Avedisian School of Medicine : Outstanding Clinical Instructor
2002 University of Kansas Medical Center: Resident of the Year Award
1995 University of Missouri: Jack Gant Award
1994 University of Missouri: Flarsheim Student Teaching Assistantship Award
1993 University of Missouri: Jack Gant Award
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Age related macular degeneration
Diabetic Retinopathy
Ocular Trauma
Retinal Detachments
Hereditary Retinal and Macular Diseases

Available to Mentor as: (Review Mentor Role Definitions):
  • Career Mentor
  • Work / Life Integration Mentor
Contact for Mentoring:

85 E. Concord St
Boston MA 02118
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