James W. Holsapple, MD
Boston University Chobanian & Avedisian School of Medicine

MD, University of Kansas
BA, Drake University

James Holsapple, MD, has been an associate professor of neurosurgery and pediatrics at BMC/BUSM since 2009. Holsapple received his undergraduate degree from Drake University, Magna Cum Laude, and his MD from University of Kansas School of Medicine. He completed an internal medicine internship at St. Luke’s Hospital, Kansas City, Missouri and a general surgery internship and neurological surgery residency at Upstate Medical University (SUNY), where he was also a NRSA Research Fellow in the Departments of Neurological Surgery and Physiology. He then joined the faculty and was promoted to Associate Professor of Neurological Surgery and Pediatrics.

A resident of South Boston, Holsapple is a member of the New England Neurological Society, the Congress of Neurological Surgeons and the American Association of Neurological Surgeons. The author of numerous papers, peer-reviewed articles, chapters and case reports, his research interests include primate visual and motor processing, human brain tumor management and biology. Holsapple’s clinical interests include adult intracranial tumors, vascular surgery and pediatric neurosurgery.

Associate Professor
Boston University Chobanian & Avedisian School of Medicine

Noninvasive intracranial Pressure Estimation-Towards a Fully Noninvasive Bedside Monitoring Device
09/01/2015 - 07/31/2023 (PI)
Massachusetts Institute of Technology / MIT Philips Healthcare

CLEAR IVH III - Clot Lysis
07/01/2009 - 06/30/2012 (PI)
Johns Hopkins University NIH-NINDS


Yr Title Project-Sub Proj Pubs

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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  1. Urbach H, Sileo N, Lerma S, Nguyen K, Sosa Soto G, Nielsen M, Heiderich A, Holsapple J, Vuppula S, Campbell JI. Ceftaroline for Central Nervous System Infections: Case Report of a Young Infant, and Scoping Review. Pediatr Infect Dis J. 2024 Mar 04.View Related Profiles. PMID: 38451889
  2. Rizzo R, Wang JWJL, DePold Hohler A, Holsapple JW, Vaou OE, Ivanov PC. Dynamic networks of cortico-muscular interactions in sleep and neurodegenerative disorders. Front Netw Physiol. 2023; 3:1168677.View Related Profiles. PMID: 37744179; PMCID: PMC10512188; DOI: 10.3389/fnetp.2023.1168677;
  3. Ravina K, Yang N, Brocoum S, Pasco-Anderson J, Walker RL, Khan M, Cabodi M, Holsapple J. Conical drill bit for optimized external ventricular drain placement: a proof-of-concept study. J Neurosurg. 2023 Sep 01; 139(3):881-891.View Related Profiles. PMID: 36790016
  4. Lee S, Kwok N, Holsapple J, Heldt T, Bourouiba L. Enhanced wall shear stress prevents obstruction by astrocytes in ventricular catheters. J R Soc Interface. 2020 07; 17(168):20190884. PMID: 32603649; PMCID: PMC7423414; DOI: 10.1098/rsif.2019.0884;
  5. Haider G, Omofoye OA, Holsapple JW. Intracranial Hypertension Following Gunshot Wound to the Torcula: Case Report and Literature Review. World Neurosurg. 2020 05; 137:94-97.View Related Profiles. PMID: 32006734
  6. Jaishankar R, Fanelli A, Filippidis A, Vu T, Holsapple J, Heldt T. A Spectral Approach to Model-Based Noninvasive Intracranial Pressure Estimation. IEEE J Biomed Health Inform. 2020 08; 24(8):2398-2406.View Related Profiles. PMID: 31880569; PMCID: PMC10615348; DOI: 10.1109/JBHI.2019.2961403;
  7. Jaishankar R, Fanelli A, Filippidis A, Vu T, Holsapple J, Heldt T. A Frequency-domain Approach to Noninvasive Intracranial Pressure Estimation. Conf Proc IEEE Eng Med Biol Soc. 2019 07; 2019:5055-5058.View Related Profiles. PMID: 31946995
  8. Mackel CE, Devaiah A, Holsapple J, Moore JM. Neural Crest Cell Failure as Embryogenesis for Fusiform Aneurysm of the Anterior Communicating Artery: Case Report and Review of the Literature. World Neurosurg. 2019 Sep; 129:232-236.View Related Profiles. PMID: 31203061
  9. Fanelli A, Jaishankar R, Filippidis A, Holsapple J, Heldt T. A Waveform Archiving System for the GE Solar 8000i Bedside Monitor. Acta Neurochir Suppl. 2018; 126:173-177.View Related Profiles. PMID: 29492556
  10. Filippidis AS, Conroy TJ, Maragkos GA, Holsapple JW, Davies KG. Intraocular Silicone Oil Migration into the Ventricles Resembling Intraventricular Hemorrhage: Case Report and Review of the Literature. World Neurosurg. 2017 Jun; 102:695.e7-695.e10.View Related Profiles. PMID: 28385656; DOI: 10.1016/j.wneu.2017.03.131;
Showing 10 of 29 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 29 publications over 22 distinct years, with a maximum of 3 publications in 2019

Contact for Mentoring:

88 E. Newton St Newton Pavilion
Boston MA 02118
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