Keywords
Last Name

Haya Herscovitz, PhD

TitleAssistant Professor
InstitutionBoston University School of Medicine
DepartmentPhysiology & Biophysics
Address700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Phone(617) 638-4012
ORCID ORCID Icon0000-0001-8067-6091
Other Positions
TitleGraduate Faculty (Primary Mentor of Grad Students)
InstitutionBoston University School of Medicine, Division of Graduate Medical Sciences

 Research Expertise & Professional Interests
Expertise includes biochemistry and cell biology.

 Self-Described Keywords
  • apolipoproteins
  • cholesterol
  • fatty acids
  • HDL
  • LDL
  • lipoproteins
  • molecular chaperones
  • resveratrol
  • SIRT1
  • transcription factors
  • triglycerides
  • VLDL
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Mei X, Liu M, Herscovitz H, Atkinson D. Probing the C-terminal domain of lipid-free apoA-I demonstrates the vital role of the H10B sequence repeat in HDL formation. J Lipid Res. 2016 Aug; 57(8):1507-17. PMID: 27317763.
    View in: PubMed
  2. Lu M, Gantz DL, Herscovitz H, Gursky O. Kinetic analysis of thermal stability of human low density lipoproteins: a model for LDL fusion in atherogenesis. J Lipid Res. 2012 Oct; 53(10):2175-85. PMID: 22855737.
    View in: PubMed
  3. Davis DA, Wilson MH, Giraud J, Xie Z, Tseng HC, England C, Herscovitz H, Tsai LH, Delalle I. Capzb2 interacts with beta-tubulin to regulate growth cone morphology and neurite outgrowth. PLoS Biol. 2009 Oct; 7(10):e1000208. PMID: 19806181.
    View in: PubMed
  4. Guha M, England C, Herscovitz H, Gursky O. Thermal transitions in human very-low-density lipoprotein: fusion, rupture, and dissociation of HDL-like particles. Biochemistry. 2007 May 22; 46(20):6043-9. PMID: 17469851.
    View in: PubMed
  5. Sommer U, Herscovitz H, Welty FK, Costello CE. LC-MS-based method for the qualitative and quantitative analysis of complex lipid mixtures. J Lipid Res. 2006 Apr; 47(4):804-14. PMID: 16443931.
    View in: PubMed
  6. Herrera VL, Tsikoudakis A, Didishvili T, Ponce LR, Bagamasbad P, Gantz D, Herscovitz H, Van Tol A, Ruiz-Opazo N. Analysis of gender-specific atherosclerosis susceptibility in transgenic[hCETP]25DS rat model. Atherosclerosis. 2004 Nov; 177(1):9-18. PMID: 15488860.
    View in: PubMed
  7. Zang M, Zuccollo A, Hou X, Nagata D, Walsh K, Herscovitz H, Brecher P, Ruderman NB, Cohen RA. AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. J Biol Chem. 2004 Nov 12; 279(46):47898-905. PMID: 15371448.
    View in: PubMed
  8. Zhang J, Herscovitz H. Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B. J Biol Chem. 2003 Feb 28; 278(9):7459-68. PMID: 12397072.
    View in: PubMed
  9. Herrera VM, Didishvili T, Lopez LV, Zander K, Traverse S, Gantz D, Herscovitz H, Ruiz-Opazo N. Hypertension exacerbates coronary artery disease in transgenic hyperlipidemic Dahl salt-sensitive hypertensive rats. Mol Med. 2001 Dec; 7(12):831-44. PMID: 11844871.
    View in: PubMed
  10. Herscovitz H, Derksen A, Walsh MT, McKnight CJ, Gantz DL, Hadzopoulou-Cladaras M, Zannis V, Curry C, Small DM. The N-terminal 17% of apoB binds tightly and irreversibly to emulsions modeling nascent very low density lipoproteins. J Lipid Res. 2001 Jan; 42(1):51-9. PMID: 11160365.
    View in: PubMed
  11. Carraway M, Herscovitz H, Zannis V, Small DM. Specificity of lipid incorporation is determined by sequences in the N-terminal 37 of apoB. Biochemistry. 2000 Aug 15; 39(32):9737-45. PMID: 10933790.
    View in: PubMed
  12. Burch WL, Herscovitz H. Disulfide bonds are required for folding and secretion of apolipoprotein B regardless of its lipidation state. J Biol Chem. 2000 May 26; 275(21):16267-74. PMID: 10747912.
    View in: PubMed
  13. Linnik KM, Herscovitz H. Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state. J Biol Chem. 1998 Aug 14; 273(33):21368-73. PMID: 9694898.
    View in: PubMed
  14. Herscovitz H, Kritis A, Talianidis I, Zanni E, Zannis V, Small DM. Murine mammary-derived cells secrete the N-terminal 41% of human apolipoprotein B on high density lipoprotein-sized lipoproteins containing a triacylglycerol-rich core. Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3):659-63. PMID: 7846033.
    View in: PubMed
  15. Meshulam T, Herscovitz H, Casavant D, Bernardo J, Roman R, Haugland RP, Strohmeier GS, Diamond RD, Simons ER. Flow cytometric kinetic measurements of neutrophil phospholipase A activation. J Biol Chem. 1992 Oct 25; 267(30):21465-70. PMID: 1400459.
    View in: PubMed
  16. Herscovitz H, Gantz D, Tercyak AM, Zannis VI, Small DM. Expression of human apolipoprotein E but not that of apolipoprotein A-I by mouse C127 cells is associated with increased secretion of lipids in the form of vesicles and discs. J Lipid Res. 1992 Jun; 33(6):791-803. PMID: 1512507.
    View in: PubMed
  17. Zoeller RA, Rangaswamy S, Herscovitz H, Rizzo WB, Hajra AK, Das AK, Moser HW, Moser A, Lazarow PB, Santos MJ. Mutants in a macrophage-like cell line are defective in plasmalogen biosynthesis, but contain functional peroxisomes. J Biol Chem. 1992 Apr 25; 267(12):8299-306. PMID: 1569085.
    View in: PubMed
  18. Herscovitz H, Hadzopoulou-Cladaras M, Walsh MT, Cladaras C, Zannis VI, Small DM. Expression, secretion, and lipid-binding characterization of the N-terminal 17% of apolipoprotein B. Proc Natl Acad Sci U S A. 1991 Aug 15; 88(16):7313-7. PMID: 1871138.
    View in: PubMed
  19. Herscovitz H, Ronen I, Bilu S, Tietz A. Bile acid synthesis from HDL cholesterol and cholesterol ester by cultured chick embryo hepatocytes. Biochim Biophys Acta. 1986 Oct 3; 878(3):426-34. PMID: 3756203.
    View in: PubMed
  20. Herscovitz H, Tietz A. The availability of different sources of cholesterol for bile acid synthesis by cultured chick embryo hepatocytes. Biochim Biophys Acta. 1985 Oct 2; 836(3):321-34. PMID: 4041475.
    View in: PubMed
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