Deborah Jean Anderson, PhD
Professor
Boston University School of Medicine
Dept of Obstetrics & Gynecology
Other OB/GYN Section

PhD, University of Texas at Austin
MS, University of Texas at Austin



I have expertise in mucosal immunology, and secondarily in virology. I am interested in immune defense of the genital tract against sexually-transmitted pathogens. We are currently working with epithelial cell lines and HIV-1 infection models.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Professor
Boston University School of Medicine
Medicine
Infectious Diseases Section

Professor
Boston University School of Medicine
Microbiology


Boston Medical Center




Project One: Development and Testing of the HCA IVR
09/13/2017 - 08/31/2018 (PI)
NIH/National Institute of Child Health &
1R01HD095631-01

Seminal microbiota and viruses associated with inflammation and HIV shedding
08/16/2016 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infe
1R21AI127706-01

Monoclonal Antibody-Based Multipurpose Microbicides
08/01/2014 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infe
5U19AI096398-05

Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen
09/13/2017 - 03/31/2018 (PI)
NIH/National Institute of Child Health &
1R01HD095630-01

Immune Modulatory Effects of Vaginal Microbiota Metabolites & HIV Susceptibility
01/09/2017 - 01/08/2018 (PI)
Burnet Institute (Melbourne, Australia) Ntl Hlth & Med Res C


Monoclonal Antibody-Based Multipurpose Microbicides
08/18/2016 - 07/31/2017 (PI)
NIH/National Institute of Allergy & Infe
3U19AI096398-05S1

Use of Anti-CD52g Antibodies to prevent HIV Transmission
07/01/2015 - 06/30/2017 (PI)
NIH/National Institute of Allergy & Infe
5R21AI121256-02

Role of Chlamydia species in preterm birth and placental dysfunction
07/01/2012 - 06/30/2017 (PI)
Boston Medical Center Corporation NIH NIAID
5R01AI101088-05

Use of a CB2 Ligand to Prevent In Vitro Transmission of HIV
06/17/2013 - 05/31/2015 (PI)
MatTek Corporation NIH NIAID
R21AI104385-02

Monoclonal Antibody-Based Multipurpose Microbicides
08/01/2013 - 08/31/2014 (PI)
NIH/National Institute of Allergy & Infe
5U19AI096398-03

Showing 10 of 25 results. Show All Results

Contraceptive Clinical Trials Network - Female Sites : Core Function Activities
06/26/2013 - 06/25/2020 (PI)
NIH-NICHD



Yr Title Project-Sub Proj Pubs
2017 Project One: Development and Testing of the HCA IVR 1R01HD095631-01
2017 Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen 1R01HD095630-01
2017 Seminal Microbiota Associated with Inflammation and HIV Transmission 5R21AI127706-02
2016 Seminal Microbiota Associated with Inflammation and HIV Transmission 1R21AI127706-01
2016 Use of Anti-CD52g Antibodies to Prevent HIV Transmission 5R21AI121256-02
2016 Monoclonal Antibody-based Multipurpose Microbicides 3U19AI096398-05S1 10
2016 Administrative Core 3U19AI096398-05S1-5038 10
2015 Monoclonal Antibody-based Multipurpose Microbicides 5U19AI096398-05 10
2015 MAbs in the Cervicovaginal Environment: Cellular Interactions and Host Defense 5U19AI096398-05-5032 10
2015 Administrative Core 5U19AI096398-05-5038 10
Showing 10 of 71 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Anderson DJ, Politch JA, Zeitlin L, Hiatt A, Kadasia K, Mayer KH, Ruprecht RM, Villinger F, Whaley KJ. Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV. AIDS. 2017 Jul 17; 31(11):1505-1517.View Related Profiles. PMID: 28463876.
  2. Zhao C, Gunawardana M, Villinger F, Baum MM, Remedios-Chan M, Moench TR, Zeitlin L, Whaley KJ, Bohorov O, Smith TJ, Anderson DJ, Moss JA. Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model. Antimicrob Agents Chemother. 2017 Jul; 61(7). PMID: 28416548; DOI: 10.1128/AAC.02465-16;.
  3. Daggett GJ, Zhao C, Connor-Stroud F, Oviedo-Moreno P, Moon H, Cho MW, Moench T, Anderson DJ, Villinger F. Comparison of the vaginal environment in rhesus and cynomolgus macaques pre- and post-lactobacillus colonization. J Med Primatol. 2017 Oct; 46(5):232-238. PMID: 28488364.
  4. Politch JA, Mayer KH, Anderson DJ. HIV-1 is undetectable in preejaculatory secretions from HIV-1-infected men on suppressive HAART. AIDS. 2016 Jul 31; 30(12):1899-903.View Related Profiles. PMID: 27124897; PMCID: PMC4955709; DOI: 10.1097/QAD.0000000000001130;.
  5. Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA. Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus. PLoS One. 2016; 11(6):e0158338. PMID: 27362256; PMCID: PMC4928780; DOI: 10.1371/journal.pone.0158338;.
  6. Chatterjee A, Ratner DM, Ryan CM, Johnson PJ, O'Keefe BR, Secor WE, Anderson DJ, Robbins PW, Samuelson J. Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model. PLoS One. 2015; 10(8):e0135340.View Related Profiles. PMID: 26252012; PMCID: PMC4529277; DOI: 10.1371/journal.pone.0135340;.
  7. Ayehunie S, Islam A, Cannon C, Landry T, Pudney J, Klausner M, Anderson DJ. Characterization of a Hormone-Responsive Organotypic Human Vaginal Tissue Model: Morphologic and Immunologic Effects. Reprod Sci. 2015 Aug; 22(8):980-90.View Related Profiles. PMID: 25676577; DOI: 10.1177/1933719115570906;.
  8. Anderson DJ, Politch JA. Role of Seminal Plasma in Human Female Reproductive Failure: Immunomodulation, Inflammation, and Infections. Adv Exp Med Biol. 2015; 868:159-69.View Related Profiles. PMID: 26178849; DOI: 10.1007/978-3-319-18881-2_7;.
  9. Anderson DJ, Le Grand R. Cell-associated HIV mucosal transmission: the neglected pathway. J Infect Dis. 2014 Dec 15; 210 Suppl 3:S606-8. PMID: 25414413; PMCID: PMC4303077; DOI: 10.1093/infdis/jiu538;.
  10. Politch JA, Marathe J, Anderson DJ. Characteristics and quantities of HIV host cells in human genital tract secretions. J Infect Dis. 2014 Dec 15; 210 Suppl 3:S609-15.View Related Profiles. PMID: 25414414; PMCID: PMC4303079; DOI: 10.1093/infdis/jiu390;.
Showing 10 of 222 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 217 publications over 37 distinct years, with a maximum of 13 publications in 1988

YearPublications
19811
19827
19836
19844
19859
19866
19877
198813
19898
19907
19914
199212
19935
199411
199512
199610
199711
19988
19997
20006
20012
20025
20033
20044
20058
20065
20074
20082
20094
20105
20115
20122
20131
20145
20153
20162
20173
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

cell-associated transmission
cervix
genital tract
HIV-1
HSV
innate immunity
Mucosal Immunology
penis
sexually transmitted infection
vagina
Contact for Mentoring:


670 Albany St Biosquare III
Boston MA 02118
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