Deborah Jean Anderson, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Infectious Diseases

PhD, University of Texas at Austin
MS, University of Texas at Austin
BA, Rice University



I have expertise in mucosal immunology, and secondarily in virology. I am interested in immune defense of the genital tract against sexually-transmitted pathogens. We are currently working with epithelial cell lines and HIV-1 infection models.

Professor
Boston University Chobanian & Avedisian School of Medicine
Obstetrics & Gynecology
Other OB/GYN

Graduate Faculty (Primary Mentor of Grad Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials
09/01/2022 - 08/31/2026 (PI)
NIH/National Institute of Child Health & Human Development
2P50HD096957-05

Development of antisperm antibody-containing penile tubes and bioadhesive films for male contraception: feasibility studies
04/01/2023 - 03/31/2025 (PI)
Male Contraceptive Initiative


Engineering bispecific antibodies for non-hormonal contraception
04/01/2021 - 03/31/2024 (Subcontract PI)
University of North Carolina at Chapel Hill NIH NICHD
5R01HD101562-03

Synthetic mRNA-Mediated Reversible Immunocontraception
09/01/2021 - 02/28/2024 (Multi-PI)
PI: Deborah Jean Anderson, PhD
Emory University NIH NICHD
5R33HD099745-04

Impact of a vaginal microbiota metabolite on epithelium integrity and HIV susceptibility
07/23/2021 - 06/30/2023 (Subcontract PI)
Burnet Institute Australian Res Coun


Nonhormonal contraceptive intravaginal ring based on high-valency anti-sperm antibody constructs
09/14/2019 - 08/31/2022 (Subcontract PI)
Mucommune LLC NIH NICHD
1R61HD099747-01

Antibody-based Contraceptive MPTs: Preclinical and Clinical Research
09/14/2018 - 08/31/2022 (PI)
NIH/National Institute of Child Health & Human Development
5P50HD096957-04

NICHD Contraception Research and Development
04/01/2022 - 04/30/2022 (PI)
Bill and Melinda Gates Foundation


Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen
09/13/2017 - 03/31/2022 (PI)
NIH/National Institute of Child Health & Human Development
5R01HD095630-04

Synthetic mRNA-Mediated Reversible Immunocontraception
09/13/2019 - 08/31/2021 (Multi-PI)
PI: Deborah Jean Anderson, PhD
Georgia Institute of Technology NIH NICHD
1R61HD099745-01

Showing 10 of 35 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2023 Synthetic mRNA-mediated reversible immunocontraception 5R33HD099745-05
2023 Project 3: Film Formulation, PK/PD and Safety Studies of ZB-06 5P50HD096957-06-5638
2023 Core A: Administration 5P50HD096957-06-7695
2023 Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials 5P50HD096957-06
2022 Synthetic mRNA-mediated reversible immunocontraception 5R33HD099745-04
2021 Synthetic mRNA-mediated reversible immunocontraception 4R33HD099745-03
2021 Preclinical Testing of Human Contraceptive Antibody (HCA) and HCA products 5P50HD096957-04-7338 1
2021 Antibody-based Contraceptive MPTs: Preclinical and Clinical Research 5P50HD096957-04 1
2021 Administrative Core 5P50HD096957-04-7336 1
2020 Synthetic mRNA-mediated reversible immunocontraception 5R61HD099745-02
Showing 10 of 98 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Nador E, Xia C, Santangelo PJ, Whaley KJ, Costello CE, Anderson DJ. Platform-Specific Fc N-Glycan Profiles of an Antisperm Antibody. Antibodies (Basel). 2024 Mar 06; 13(1).View Related Profiles. PMID: 38534207; PMCID: PMC10967333; DOI: 10.3390/antib13010017;
     
  2. Johnson JA, Li JF, Politch JA, Lipscomb JT, Santos Tino A, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen under INSTI-based Therapy are Largely Myeloid Cell-Derived and Disparate from Circulating Provirus. J Infect Dis. 2024 Feb 13.View Related Profiles. PMID: 38356153
     
  3. Dohadwala S, Geib MT, Politch JA, Anderson DJ. Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended pregnancy. Front Reprod Health. 2023; 5:1337479.View Related Profiles. PMID: 38264184; PMCID: PMC10803587; DOI: 10.3389/frph.2023.1337479;
     
  4. Dohadwala S, Politch JA, Barmine JH, Anderson DJ. A Brief History and Advancement of Contraceptive Multipurpose Prevention Technology (cMPT) Products. Open Access J Contracept. 2023; 14:83-94.View Related Profiles. PMID: 37332341; PMCID: PMC10276588; DOI: 10.2147/OAJC.S375634;
     
  5. Anderson DJ, Johnston DS. A brief history and future prospects of contraception. Science. 2023 Apr 14; 380(6641):154-158. PMID: 37053322; PMCID: PMC10615352; DOI: 10.1126/science.adf9341;
     
  6. Mausser E, Nador E, Politch JA, Pauly MR, Marathe JG, Moench TR, Zeitlin L, Whaley KJ, Anderson DJ. LALAPG variant of the Human Contraception Antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity. PLoS One. 2023; 18(3):e0282147.View Related Profiles. PMID: 36996137; PMCID: PMC10062632; DOI: 10.1371/journal.pone.0282147;
     
  7. Thurman AR, Moench TR, Hoke M, Politch JA, Cabral H, Mausser E, Nador E, Morton J, Hamorsky K, Swope K, Bratcher B, Anderson DJ, Whaley KJ. ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study. Am J Obstet Gynecol. 2023 Jun; 228(6):716.e1-716.e12.View Related Profiles. PMID: 36870409; PMCID: PMC10247457; DOI: 10.1016/j.ajog.2023.02.024;
     
  8. Lee SG, Kiattiburut W, Khongkha T, Schinkel SCB, Lunn Y, Decker AP, Mohammadi A, Vera-Cruz A, Misra A, Angel JB, Anderson DJ, Baker M, Kaul R, Wang G, Tanphaichitr N. 17BIPHE2, an engineered cathelicidin antimicrobial peptide with low susceptibility to proteases, is an effective spermicide and microbicide against Neisseria gonorrhoeae. Hum Reprod. 2022 Oct 31; 37(11):2503-2517. PMID: 36053257; PMCID: PMC9724780; DOI: 10.1093/humrep/deac188;
     
  9. Patten JJ, Keiser PT, Morselli-Gysi D, Menichetti G, Mori H, Donahue CJ, Gan X, Valle ID, Geoghegan-Barek K, Anantpadma M, Boytz R, Berrigan JL, Stubbs SH, Ayazika T, O'Leary C, Jalloh S, Wagner F, Ayehunie S, Elledge SJ, Anderson D, Loscalzo J, Zitnik M, Gummuluru S, Namchuk MN, Barabási AL, Davey RA. Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization. iScience. 2022 Sep 16; 25(9):104925.View Related Profiles. PMID: 35992305; PMCID: PMC9374494; DOI: 10.1016/j.isci.2022.104925;
     
  10. Anderson DJ. Passive immunization of the human vagina. Hum Vaccin Immunother. 2022 Apr 29; 18(2):1965423. PMID: 34473605; PMCID: PMC9103259; DOI: 10.1080/21645515.2021.1965423;
     
Showing 10 of 303 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 293 publications over 44 distinct years, with a maximum of 19 publications in 1997

YearPublications
19812
19828
19839
19844
198511
19869
198713
198816
19898
19908
19915
199215
19937
199412
199513
199611
199719
199811
19999
20007
20015
20026
20033
20044
20059
20066
20074
20082
20094
20105
20115
20122
20132
201412
20154
20163
20174
20181
20192
20201
20213
20222
20234
20243

2011 National Institute of Allergy and Infectious Diseases (NIAID): Research Grant
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

cell-associated transmission
cervix
genital tract
HIV-1
HSV
innate immunity
Mucosal Immunology
penis
sexually transmitted infection
vagina
Contact for Mentoring:

670 Albany St Biosquare III
Boston MA 02118
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