Deborah Jean Anderson, PhD
Professor
Boston University School of Medicine
Dept of Obstetrics & Gynecology
Other OB/GYN

PhD, University of Texas at Austin
MS, University of Texas at Austin



I have expertise in mucosal immunology, and secondarily in virology. I am interested in immune defense of the genital tract against sexually-transmitted pathogens. We are currently working with epithelial cell lines and HIV-1 infection models.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Professor
Boston University School of Medicine
Medicine
Infectious Diseases

Professor
Boston University School of Medicine
Microbiology


Boston Medical Center



2011 National Institute of Allergy and Infectious Diseases (NIAID): Research Grant


Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen
09/13/2017 - 03/31/2021 (PI)
NIH/National Institute of Child Health & Human Development
5R01HD095630-02

Project One: Development and Testing of the HCA IVR
09/13/2017 - 08/31/2018 (PI)
NIH/National Institute of Child Health & Human Development
1R01HD095631-01

Seminal microbiota and viruses associated with inflammation and HIV shedding
08/16/2016 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI127706-02

Monoclonal Antibody-Based Multipurpose Microbicides
08/01/2014 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5U19AI096398-05

Immune Modulatory Effects of Vaginal Microbiota Metabolites & HIV Susceptibility
01/09/2017 - 01/08/2018 (PI)
Burnet Institute (Melbourne, Australia) Ntl Hlth & Med Res C


Monoclonal Antibody-Based Multipurpose Microbicides
08/18/2016 - 07/31/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
3U19AI096398-05S1

Use of Anti-CD52g Antibodies to prevent HIV Transmission
07/01/2015 - 06/30/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121256-02

Role of Chlamydia species in preterm birth and placental dysfunction
07/01/2012 - 06/30/2017 (PI)
Boston Medical Center Corporation NIH NIAID
5R01AI101088-05

Monoclonal Antibody-Based Multipurpose Microbicides
08/01/2013 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5U19AI096398-03

Monoclonal Antibody-based Multipurpose Microbicides
08/01/2012 - 07/31/2016 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5U19AI096398-02

Showing 10 of 25 results. Show All Results



Yr Title Project-Sub Proj Pubs
2018 Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen 5R01HD095630-02
2017 Project One: Development and Testing of the HCA IVR 1R01HD095631-01
2017 Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen 1R01HD095630-01
2017 Seminal Microbiota Associated with Inflammation and HIV Transmission 5R21AI127706-02
2016 Seminal Microbiota Associated with Inflammation and HIV Transmission 1R21AI127706-01
2016 Use of Anti-CD52g Antibodies to Prevent HIV Transmission 5R21AI121256-02
2016 Monoclonal Antibody-based Multipurpose Microbicides 3U19AI096398-05S1 10
2016 Administrative Core 3U19AI096398-05S1-5038 10
2015 Monoclonal Antibody-based Multipurpose Microbicides 5U19AI096398-05 10
2015 MAbs in the Cervicovaginal Environment: Cellular Interactions and Host Defense 5U19AI096398-05-5032 10
Showing 10 of 72 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Pudney J, Wangu Z, Panther L, Fugelso D, Marathe J, Sagar M, Politch JA, Anderson DJ. Condylomata acuminata (anogenital warts) contain accumulations of HIV-1 target cells that may provide portals for HIV transmission. J Infect Dis. 2018 Aug 18.View Related Profiles. PMID: 30137482.
     
  2. Anderson DJ, Politch JA, Zeitlin L, Hiatt A, Kadasia K, Mayer KH, Ruprecht RM, Villinger F, Whaley KJ. Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV. AIDS. 2017 Jul 17; 31(11):1505-1517.View Related Profiles. PMID: 28463876.
     
  3. Zhao C, Gunawardana M, Villinger F, Baum MM, Remedios-Chan M, Moench TR, Zeitlin L, Whaley KJ, Bohorov O, Smith TJ, Anderson DJ, Moss JA. Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model. Antimicrob Agents Chemother. 2017 Jul; 61(7). PMID: 28416548; DOI: 10.1128/AAC.02465-16;.
     
  4. Daggett GJ, Zhao C, Connor-Stroud F, Oviedo-Moreno P, Moon H, Cho MW, Moench T, Anderson DJ, Villinger F. Comparison of the vaginal environment in rhesus and cynomolgus macaques pre- and post-lactobacillus colonization. J Med Primatol. 2017 Oct; 46(5):232-238. PMID: 28488364.
     
  5. Hearps AC, Tyssen D, Srbinovski D, Bayigga L, Diaz DJD, Aldunate M, Cone RA, Gugasyan R, Anderson DJ, Tachedjian G. Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition. Mucosal Immunol. 2017 Nov; 10(6):1480-1490. PMID: 28401934.
     
  6. Politch JA, Mayer KH, Anderson DJ. HIV-1 is undetectable in preejaculatory secretions from HIV-1-infected men on suppressive HAART. AIDS. 2016 Jul 31; 30(12):1899-903.View Related Profiles. PMID: 27124897; PMCID: PMC4955709; DOI: 10.1097/QAD.0000000000001130;.
     
  7. Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA. Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus. PLoS One. 2016; 11(6):e0158338. PMID: 27362256; PMCID: PMC4928780; DOI: 10.1371/journal.pone.0158338;.
     
  8. Kadasia K, Chung AW, Alter G, Anderson D. AIDS Research and Human Retroviruses. Testing Human Anti-HIV Monoclonal Antibodies Produced in Nicotiana for Activity Against Cell-associated HIV. 2016.
     
  9. Chatterjee A, Ratner DM, Ryan CM, Johnson PJ, O'Keefe BR, Secor WE, Anderson DJ, Robbins PW, Samuelson J. Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal Model. PLoS One. 2015; 10(8):e0135340.View Related Profiles. PMID: 26252012; PMCID: PMC4529277; DOI: 10.1371/journal.pone.0135340;.
     
  10. Ayehunie S, Islam A, Cannon C, Landry T, Pudney J, Klausner M, Anderson DJ. Characterization of a Hormone-Responsive Organotypic Human Vaginal Tissue Model: Morphologic and Immunologic Effects. Reprod Sci. 2015 Aug; 22(8):980-90.View Related Profiles. PMID: 25676577; DOI: 10.1177/1933719115570906;.
     
Showing 10 of 288 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 278 publications over 38 distinct years, with a maximum of 19 publications in 1997

YearPublications
19812
19828
19839
19844
198511
19869
198713
198816
19898
19908
19915
199215
19937
199412
199513
199611
199719
199811
19999
20007
20015
20026
20033
20044
20059
20066
20074
20082
20094
20105
20115
20122
20132
201412
20154
20163
20174
20181
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

cell-associated transmission
cervix
genital tract
HIV-1
HSV
innate immunity
Mucosal Immunology
penis
sexually transmitted infection
vagina
Contact for Mentoring:


670 Albany St Biosquare III
Boston MA 02118
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