Deborah Jean Anderson, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Infectious Diseases

PhD, University of Texas at Austin
MS, University of Texas at Austin




I have expertise in mucosal immunology, and secondarily in virology. I am interested in immune defense of the genital tract against sexually-transmitted pathogens. We are currently working with epithelial cell lines and HIV-1 infection models.

Professor
Boston University School of Medicine
Obstetrics & Gynecology
Other OB/GYN

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Graduate Medical Sciences



2011 National Institute of Allergy and Infectious Diseases (NIAID): Research Grant


Antibody-based Contraceptive MPTs: Preclinical and Clinical Research
09/14/2018 - 03/31/2022 (PI)
NIH/National Institute of Child Health & Human Development
5P50HD096957-02

Synthetic mRNA-Mediated Reversible Immunocontraception
09/13/2019 - 08/31/2021 (Subcontract PI)
Georgia Institute of Technology NIH NICHD
1R61HD099745-01

Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen
09/13/2017 - 03/31/2021 (PI)
NIH/National Institute of Child Health & Human Development
5R01HD095630-03

INSTI PrEP Study
09/23/2018 - 09/22/2019 (Subcontract PI)
Fenway Community Health Center, Inc. HHS CDC


Project One: Development and Testing of the HCA IVR
09/13/2017 - 08/31/2018 (PI)
NIH/National Institute of Child Health & Human Development
1R01HD095631-01

Monoclonal Antibody-Based Multipurpose Microbicides
08/18/2016 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
3U19AI096398-05S1

Seminal microbiota and viruses associated with inflammation and HIV shedding
08/16/2016 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI127706-02

Monoclonal Antibody-Based Multipurpose Microbicides
08/01/2014 - 07/31/2018 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5U19AI096398-05

Immune Modulatory Effects of Vaginal Microbiota Metabolites & HIV Susceptibility
01/09/2017 - 01/08/2018 (Subcontract PI)
Burnet Institute (Melbourne, Australia) Ntl Hlth & Med Res C


Use of Anti-CD52g Antibodies to prevent HIV Transmission
07/01/2015 - 06/30/2017 (PI)
NIH/National Institute of Allergy & Infectious Diseases
5R21AI121256-02

Showing 10 of 28 results. Show All Results

Contraceptive Clinical Trials Network - Female Sites : Core Function Activities
06/26/2013 - 06/30/2020 (PI)
NIH-NICHD


Title


Yr Title Project-Sub Proj Pubs
2020 Antibody-based Contraceptive MPTs: Preclinical and Clinical Research 5P50HD096957-03 1
2020 Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen 5R01HD095630-04
2020 Administrative Core 5P50HD096957-03-7336 1
2020 Preclinical Testing of Human Contraceptive Antibody (HCA) and HCA products 5P50HD096957-03-7338 1
2019 Synthetic mRNA-mediated reversible immunocontraception 1R61HD099745-01
2019 Antibody-based Contraceptive MPTs: Preclinical and Clinical Research 5P50HD096957-02 1
2019 Project Three: Assessing effects of anti-CD52g Mabs on STD pathogens in semen 5R01HD095630-03
2019 Administrative Core 5P50HD096957-02-7336 1
2019 Preclinical Testing of Human Contraceptive Antibody (HCA) and HCA products 5P50HD096957-02-7338 1
2018 Antibody-based Contraceptive MPTs: Preclinical and Clinical Research 1U54HD096957-01 1
Showing 10 of 88 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Anderson DJ, Politch JA, Cone RA, Zeitlin L, Lai SK, Santangelo PJ, Moench TR, Whaley KJ. Engineering monoclonal antibody-based contraception and multipurpose prevention technologies†. Biol Reprod. 2020 Aug 04; 103(2):275-285.View Related Profiles. PMID: 32607584
     
  2. Anderson DJ. Population and the Environment - Time for Another Contraception Revolution. N Engl J Med. 2019 Aug 01; 381(5):397-399. PMID: 31365795
     
  3. Pudney J, Wangu Z, Panther L, Fugelso D, Marathe JG, Sagar M, Politch JA, Anderson DJ. Condylomata Acuminata (Anogenital Warts) Contain Accumulations of HIV-1 Target Cells That May Provide Portals for HIV Transmission. J Infect Dis. 2019 01 07; 219(2):275-283.View Related Profiles. PMID: 30137482
     
  4. Bayigga L, Kateete DP, Anderson DJ, Sekikubo M, Nakanjako D. Diversity of vaginal microbiota in sub-Saharan Africa and its effects on HIV transmission and prevention. Am J Obstet Gynecol. 2019 02; 220(2):155-166. PMID: 30321529
     
  5. Anderson DJ, Politch JA, Zeitlin L, Hiatt A, Kadasia K, Mayer KH, Ruprecht RM, Villinger F, Whaley KJ. Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV. AIDS. 2017 Jul 17; 31(11):1505-1517.View Related Profiles. PMID: 28463876
     
  6. Zhao C, Gunawardana M, Villinger F, Baum MM, Remedios-Chan M, Moench TR, Zeitlin L, Whaley KJ, Bohorov O, Smith TJ, Anderson DJ, Moss JA. Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model. Antimicrob Agents Chemother. 2017 Jul; 61(7). PMID: 28416548; DOI: 10.1128/AAC.02465-16;
     
  7. Daggett GJ, Zhao C, Connor-Stroud F, Oviedo-Moreno P, Moon H, Cho MW, Moench T, Anderson DJ, Villinger F. Comparison of the vaginal environment in rhesus and cynomolgus macaques pre- and post-lactobacillus colonization. J Med Primatol. 2017 Oct; 46(5):232-238. PMID: 28488364
     
  8. Hearps AC, Tyssen D, Srbinovski D, Bayigga L, Diaz DJD, Aldunate M, Cone RA, Gugasyan R, Anderson DJ, Tachedjian G. Vaginal lactic acid elicits an anti-inflammatory response from human cervicovaginal epithelial cells and inhibits production of pro-inflammatory mediators associated with HIV acquisition. Mucosal Immunol. 2017 Nov; 10(6):1480-1490. PMID: 28401934
     
  9. Politch JA, Mayer KH, Anderson DJ. HIV-1 is undetectable in preejaculatory secretions from HIV-1-infected men on suppressive HAART. AIDS. 2016 Jul 31; 30(12):1899-903.View Related Profiles. PMID: 27124897; PMCID: PMC4955709; DOI: 10.1097/QAD.0000000000001130;
     
  10. Wang YY, Schroeder HA, Nunn KL, Woods K, Anderson DJ, Lai SK, Cone RA. Diffusion of Immunoglobulin G in Shed Vaginal Epithelial Cells and in Cell-Free Regions of Human Cervicovaginal Mucus. PLoS One. 2016; 11(6):e0158338. PMID: 27362256; PMCID: PMC4928780; DOI: 10.1371/journal.pone.0158338;
     
Showing 10 of 291 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 281 publications over 40 distinct years, with a maximum of 19 publications in 1997

YearPublications
19812
19828
19839
19844
198511
19869
198713
198816
19898
19908
19915
199215
19937
199412
199513
199611
199719
199811
19999
20007
20015
20026
20033
20044
20059
20066
20074
20082
20094
20105
20115
20122
20132
201412
20154
20163
20174
20181
20192
20201
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

cell-associated transmission
cervix
genital tract
HIV-1
HSV
innate immunity
Mucosal Immunology
penis
sexually transmitted infection
vagina
Contact for Mentoring:

670 Albany St Biosquare III
Boston MA 02118
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