Deborah Jean Anderson, PhD
Professor
Boston University Chobanian & Avedisian School of Medicine
Medicine
Infectious Diseases

PhD, University of Texas at Austin
MS, University of Texas at Austin
BA, Rice University



I have expertise in mucosal immunology, and secondarily in virology. I am interested in immune defense of the genital tract against sexually-transmitted pathogens. We are currently working with epithelial cell lines and HIV-1 infection models.

Professor
Boston University Chobanian & Avedisian School of Medicine
Obstetrics & Gynecology
Other OB/GYN

Graduate Medical Sciences Educator and Mentor (Primary Mentor of Graduate Students)
Boston University Chobanian & Avedisian School of Medicine, Graduate Medical Sciences




Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials
09/01/2023 - 08/31/2026 (PI)
NIH/National Institute of Child Health & Human Development
5P50HD096957-06

Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials
09/01/2022 - 08/31/2026 (PI)
NIH/National Institute of Child Health & Human Development
5P50HD096957-08

Development of a bioadhesive vaginal film for extended release of MPT antibodies
02/01/2025 - 01/31/2026 (Subcontract PI)
Magee-Womens Research Institute and Foundation NIH NICHD
1R61HD117426-01

Synthetic mRNA-Mediated Reversible Immunocontraception
09/01/2021 - 08/31/2025 (Multi-PI)
PI: Deborah Jean Anderson, PhD
Emory University NIH NICHD
5R33HD099745-05

Development of antisperm antibody-containing penile tubes and bioadhesive films for male contraception: feasibility studies
04/01/2023 - 03/31/2025 (PI)
Male Contraceptive Initiative


Engineering bispecific antibodies for non-hormonal contraception
04/01/2021 - 03/31/2025 (Subcontract PI)
University of North Carolina at Chapel Hill NIH NICHD
5R01HD101562-03

Impact of a vaginal microbiota metabolite on epithelium integrity and HIV susceptibility
07/23/2021 - 06/30/2023 (Subcontract PI)
The Macfarlane Burnet Institute for Medical Research and Public Health, LTD Australian Res Coun


Nonhormonal contraceptive intravaginal ring based on high-valency anti-sperm antibody constructs
09/14/2019 - 08/31/2022 (Subcontract PI)
Mucommune LLC NIH NICHD
1R61HD099747-01

Antibody-based Contraceptive MPTs: Preclinical and Clinical Research
09/14/2018 - 08/31/2022 (Multi-PI)
PI: Deborah Jean Anderson, PhD
NIH/National Institute of Child Health & Human Development
5P50HD096957-04

NICHD Contraception Research and Development
04/01/2022 - 04/30/2022 (PI)
Bill and Melinda Gates Foundation


Showing 10 of 37 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2025 Development of a bioadhesive vaginal film for extended release of MPT antibodies 1R61HD117426-01
2025 Project 3: Film Formulation, PK/PD and Safety Studies of ZB-06 5P50HD096957-08-5638
2025 Core A: Administration 5P50HD096957-08-7695
2025 Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials 5P50HD096957-08
2024 Project 3: Film Formulation, PK/PD and Safety Studies of ZB-06 5P50HD096957-07-5638
2024 Antibody-based Contraceptive MPTs: Advancing the Human Contraceptive Antibody (HCA) through Clinical Trials 5P50HD096957-07
2024 Core A: Administration 5P50HD096957-07-7695
2023 Synthetic mRNA-mediated reversible immunocontraception 5R33HD099745-05
2023 Project 3: Film Formulation, PK/PD and Safety Studies of ZB-06 5P50HD096957-06-5638
2023 Core A: Administration 5P50HD096957-06-7695
Showing 10 of 105 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Website       Copy PMIDs To Clipboard

  1. Dohadwala S, Shah P, Farrell MK, Politch JA, Marathe J, Costello CE, Anderson DJ. Sialidases derived from Gardnerella vaginalis and Prevotella timonensis remodel the sperm glycocalyx and impair sperm function. Glycobiology. 2025 Nov 06; 35(11).View Related Profiles. PMID: 41165775; DOI: 10.1093/glycob/cwaf067;
     
  2. Anderson DJ, Bearak JM, Grimstad FW, Palanee-Phillips T, van der Straten A. Biomedical innovations in contraception: gaps, obstacles, and solutions for sexual and reproductive health. Lancet. 2025 Nov 01; 406(10515):2119-2132. PMID: 41176392; DOI: 10.1016/S0140-6736(25)01187-0;
     
  3. Doud JM, Geib MT, Politch JA, Whaley K, Anderson DJ, Marathe JG. Revolutionizing male contraception: Personal lubricants as a novel way to deliver the Human Contraception Antibody. bioRxiv. 2025 Aug 20.View Related Profiles. PMID: 40894626; PMCID: PMC12393346; DOI: 10.1101/2025.08.14.670442;
     
  4. Dohadwala S, Shah P, Farrell M, Politch J, Marathe J, Costello CE, Anderson DJ. Sialidases derived from Gardnerella vaginalis remodel the sperm glycocalyx and impair sperm function. bioRxiv. 2025 Feb 05.View Related Profiles. PMID: 39975358; PMCID: PMC11838519; DOI: 10.1101/2025.02.01.636076;
     
  5. Nador E, Mausser E, Marathe JG, Politch JA, Thurman AR, Whaley KJ, Anderson DJ. Antibody-dependent complement-mediated sperm cytotoxicity in the endocervix is a dominant contraceptive mechanism of ZB-06 vaginal film. Fertil Steril. 2025 Mar; 123(3):534-536.View Related Profiles. PMID: 39447830; PMCID: PMC12269741; DOI: 10.1016/j.fertnstert.2024.10.026;
     
  6. Johnson JA, Li JF, Politch JA, Lipscomb JT, Tino AS, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen Under Integrase Strand Transfer Inhibitor-Based Therapy Are Largely Myeloid Cell-Derived and Disparate. J Infect Dis. 2024 Jul 25; 230(1):78-85.View Related Profiles. PMID: 39052738
     
  7. Nador E, Xia C, Santangelo PJ, Whaley KJ, Costello CE, Anderson DJ. Platform-Specific Fc N-Glycan Profiles of an Antisperm Antibody. Antibodies (Basel). 2024 Mar 06; 13(1).View Related Profiles. PMID: 38534207; PMCID: PMC10967333; DOI: 10.3390/antib13010017;
     
  8. Johnson JA, Li JF, Politch JA, Lipscomb JT, Santos Tino A, DeFelice J, Gelman M, Anderson DJ, Mayer KH. HIV Immunocapture Reveals Particles Expressed in Semen under INSTI-based Therapy are Largely Myeloid Cell-Derived and Disparate from Circulating Provirus. J Infect Dis. 2024 Feb 13.View Related Profiles. PMID: 38356153
     
  9. Dohadwala S, Geib MT, Politch JA, Anderson DJ. Innovations in monoclonal antibody-based multipurpose prevention technology (MPT) for the prevention of sexually transmitted infections and unintended pregnancy. Front Reprod Health. 2023; 5:1337479.View Related Profiles. PMID: 38264184; PMCID: PMC10803587; DOI: 10.3389/frph.2023.1337479;
     
  10. Dohadwala S, Politch JA, Barmine JH, Anderson DJ. A Brief History and Advancement of Contraceptive Multipurpose Prevention Technology (cMPT) Products. Open Access J Contracept. 2023; 14:83-94.View Related Profiles. PMID: 37332341; PMCID: PMC10276588; DOI: 10.2147/OAJC.S375634;
     
Showing 10 of 309 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 299 publications over 45 distinct years, with a maximum of 19 publications in 1997

YearPublications
19812
19828
19839
19844
198511
19869
198713
198816
19898
19908
19915
199215
19937
199412
199513
199611
199719
199811
19999
20007
20015
20026
20033
20044
20059
20066
20074
20082
20094
20105
20115
20122
20132
201412
20154
20163
20174
20181
20192
20201
20213
20222
20234
20245
20254


Recent (within 3 months)

Persistent gaps in contraception access identified

Contemporary OB/GYN 11/11/2025

‘Stuck with condoms and vasectomies’ – Researchers working on better birth control choices for men

Boston 25 News 11/5/2025

Older

Sexual Health and HIV Care Integration Key to Better Care | IAS 2025

Managed Healthcare Executive 7/14/2025

The Coming Birth-Control Revolution

The Atlantic 4/3/2024

Where is all the hormone-free birth control?

Popular Science 2/26/2023

A New Breed of Nonhormonal Birth Control

BU Today 11/30/2022

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

News Medical 9/15/2022

An Experimental Birth Control Attacks Sperm Like a Virus

Wired 8/30/2021

Topical contraceptive safely, effectively immobilizes sperm

Healio 8/16/2021

Antibiotic from potato-infecting microbe could help treat Candida

Medical News Today 6/27/2020

Sex Myths: Fact or Fiction

Psychology Today 2/6/2020

A birth control pill lasts one month in pigs. Will it work in humans?

Chemical & Engineering News 12/11/2019

MIT researchers are developing a once-a-month birth control pill

The Boston Globe 12/4/2019

Growth of Population Could be Curbed with the ‘Contraceptive Revolution’

Medgazette 8/19/2019

‘Contraceptive Revolution’ Needed to Curb Population Growth

BioEdge 8/11/2019

To mitigate the effects of climate change, one researcher calls for a ‘contraception revolution’

STAT 8/1/2019

Why We Need a Contraception Revolution

BU Today 8/1/2019

Scientists Are Trying To Create A Contraceptive That Stops Sperm In Its Tracks

STAT 11/20/2018

2011 National Institute of Allergy and Infectious Diseases (NIAID): Research Grant
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

cell-associated transmission
cervix
genital tract
HIV-1
HSV
innate immunity
Mucosal Immunology
penis
sexually transmitted infection
vagina
Contact for Mentoring:

670 Albany St Biosquare III
Boston MA 02118
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