Colin Murdoch

Postdoctoral Fellow (previously held)

Boston University Chobanian & Avedisian School of Medicine

Vascular Biology

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University of Dundee School of Medicine

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Musale V, Murdoch CE, Banah AK, Hasib A, Hennayake CK, Dong B, Lang CC, Wasserman DH, Kang L. Limiting extracellular matrix expansion in diet-induced obese mice reduces cardiac insulin resistance and prevents myocardial remodelling. Mol Metab. 2024 Aug; 86:101970. PMID: 38908792; PMCID: PMC11334943; DOI: 10.1016/j.molmet.2024.101970;

Lermant A, Rabussier G, Davidson L, Lanz HL, Murdoch CE. Protocol for a placenta-on-a-chip model using trophoblasts differentiated from human induced pluripotent stem cells. STAR Protoc. 2024 Mar 15; 5(1):102879. PMID: 38358879; PMCID: PMC10876593; DOI: 10.1016/j.xpro.2024.102879;

Markwalder L, Gush R, Khan F, Murdoch CE, Krstajic N. In vivo laser speckle contrast imaging of microvascular blood perfusion using a chip-on-tip camera. iScience. 2024 Mar 15; 27(3):109077. PMID: 38375226; PMCID: PMC10875563; DOI: 10.1016/j.isci.2024.109077;

Musale V, Murdoch CE, Banah AK, Hasib A, Hennayake CK, Dong B, Lang CC, Wasserman DH, Kang L. Extracellular Matrix Abnormalities Contribute to Cardiac Insulin Resistance and Associated Dysfunction in Diet-induced Obese Mice. bioRxiv. 2023 Nov 16. PMID: 38014154; PMCID: PMC10680679; DOI: 10.1101/2023.11.14.567128;

Lermant A, Rabussier G, Lanz HL, Davidson L, Porter IM, Murdoch CE. Development of a human iPSC-derived placental barrier-on-chip model. iScience. 2023 Jul 21; 26(7):107240. PMID: 37534160; PMCID: PMC10392097; DOI: 10.1016/j.isci.2023.107240;

Rabussier G, Bünter I, Bouwhuis J, Soragni C, van Zijp T, Ng CP, Domansky K, de Windt LJ, Vulto P, Murdoch CE, Bircsak KM, Lanz HL. Healthy and diseased placental barrier on-a-chip models suitable for standardized studies. Acta Biomater. 2023 Jul 01; 164:363-376. PMID: 37116636

Apicella C, Ruano CSM, Thilaganathan B, Khalil A, Giorgione V, Gascoin G, Marcellin L, Gaspar C, Jacques S, Murdoch CE, Miralles F, Méhats C, Vaiman D. Pan-Genomic Regulation of Gene Expression in Normal and Pathological Human Placentas. Cells. 2023 Feb 10; 12(4). PMID: 36831244; PMCID: PMC9954093; DOI: 10.3390/cells12040578;

Soragni C, Rabussier G, Lanz HL, Bircsak KM, de Windt LJ, Trietsch SJ, Murdoch CE, Ng CP. A versatile multiplexed assay to quantify intracellular ROS and cell viability in 3D on-a-chip models. Redox Biol. 2022 Nov; 57:102488. PMID: 36201911; PMCID: PMC9535429; DOI: 10.1016/j.redox.2022.102488;

Di Fabrizio C, Giorgione V, Khalil A, Murdoch CE. Antioxidants in Pregnancy: Do We Really Need More Trials? Antioxidants (Basel). 2022 Apr 22; 11(5). PMID: 35624676; PMCID: PMC9137466; DOI: 10.3390/antiox11050812;

Monteiro O, Bhaskar A, Ng AKM, Murdoch CE, Baptista-Hon DT. Computer-based virtual laboratory simulations: LabHEART cardiac physiology practical. Adv Physiol Educ. 2021 Dec 01; 45(4):856-868. PMID: 34473584

Showing 10 of 42 results. Show More

Wang M, Murdoch CE, Brewer AC, Ivetic A, Evans P, Shah AM, Zhang M. Endothelial NADPH oxidase 4 protects against angiotensin II-induced cardiac fibrosis and inflammation. ESC Heart Fail. 2021 04; 8(2):1427-1437. PMID: 33511759; PMCID: PMC8006688; DOI: 10.1002/ehf2.13228;

Murdoch CE, De Falco E. Antioxidant synthetic peptides counteracting hyperglycaemia induced endothelial cell dysfunction. Int J Cardiol. 2020 06 01; 308:82-83. PMID: 32247574

Yura Y, Chong BSH, Johnson RD, Watanabe Y, Tsukahara Y, Ferran B, Murdoch CE, Behring JB, McComb ME, Costello CE, Janssen-Heininger YMW, Cohen RA, Bachschmid MM, Matsui R. Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice. FASEB J. 2019 12; 33(12):14147-14158.View Related Profiles.

Chong, Brian
Costello, Catherine
Murdoch, Colin
Behring, Jessica
McComb, Mark
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Tsukahara, Yuko

PMID: 31647879; PMCID: PMC6894059; DOI: 10.1096/fj.201900786R;

Lermant A, Murdoch CE. Cysteine Glutathionylation Acts as a Redox Switch in Endothelial Cells. Antioxidants (Basel). 2019 Aug 16; 8(8). PMID: 31426416; PMCID: PMC6720164; DOI: 10.3390/antiox8080315;

Weinberg EO, Ferran B, Tsukahara Y, Hatch MMS, Han J, Murdoch CE, Matsui R. IL-33 induction and signaling are controlled by glutaredoxin-1 in mouse macrophages. PLoS One. 2019; 14(1):e0210827.View Related Profiles.

Murdoch, Colin
Han, Jingyan
Matsui, Reiko
Tsukahara, Yuko

PMID: 30682073; PMCID: PMC6347181; DOI: 10.1371/journal.pone.0210827;

Wang Z, Stuckey DJ, Murdoch CE, Camelliti P, Lip GYH, Griffin M. Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor. Cell Death Dis. 2018 04 27; 9(6):613. PMID: 29795262; PMCID: PMC5966415; DOI: 10.1038/s41419-018-0573-2;

Guo D, Murdoch CE, Liu T, Qu J, Jiao S, Wang Y, Wang W, Chen X. Therapeutic Angiogenesis of Chinese Herbal Medicines in Ischemic Heart Disease: A Review. Front Pharmacol. 2018; 9:428. PMID: 29755358; PMCID: PMC5932161; DOI: 10.3389/fphar.2018.00428;

Guo D, Murdoch CE, Xu H, Shi H, Duan DD, Ahmed A, Gu Y. Vascular endothelial growth factor signaling requires glycine to promote angiogenesis. Sci Rep. 2017 11 07; 7(1):14749. PMID: 29116138; PMCID: PMC5677092; DOI: 10.1038/s41598-017-15246-3;

Angelini F, Pagano F, Bordin A, Milan M, Chimenti I, Peruzzi M, Valenti V, Marullo A, Schirone L, Palmerio S, Sciarretta S, Murdoch CE, Frati G, De Falco E. The Impact of Environmental Factors in Influencing Epigenetics Related to Oxidative States in the Cardiovascular System. Oxid Med Cell Longev. 2017; 2017:2712751. PMID: 28607629; PMCID: PMC5457758; DOI: 10.1155/2017/2712751;

Matsui R, Watanabe Y, Murdoch CE. Redox regulation of ischemic limb neovascularization - What we have learned from animal studies. Redox Biol. 2017 Aug; 12:1011-1019.View Related Profiles.

Murdoch, Colin
Matsui, Reiko

PMID: 28505880; PMCID: PMC5430575; DOI: 10.1016/j.redox.2017.04.040;

Sag CM, Schnelle M, Zhang J, Murdoch CE, Kossmann S, Protti A, Santos CXC, Sawyer G, Zhang X, Mongue-Din H, Richards DA, Brewer AC, Prysyazhna O, Maier LS, Wenzel P, Eaton PJ, Shah AM. Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell NAPDH Oxidase 2 on Blood Pressure. Circulation. 2017 May 30; 135(22):2163-2177. PMID: 28298457; PMCID: PMC5444427; DOI: 10.1161/CIRCULATIONAHA.116.023877;

Cai M, Wang K, Murdoch CE, Gu Y, Ahmed A. Heterodimerisation between VEGFR-1 and VEGFR-2 and not the homodimers of VEGFR-1 inhibit VEGFR-2 activity. Vascul Pharmacol. 2017 Jan; 88:11-20. PMID: 27884759; DOI: 10.1016/j.vph.2016.11.007;

Sirker A, Murdoch CE, Protti A, Sawyer GJ, Santos CX, Martin D, Zhang X, Brewer AC, Zhang M, Shah AM. Cell-specific effects of Nox2 on the acute and chronic response to myocardial infarction. J Mol Cell Cardiol. 2016 Sep; 98:11-7. PMID: 27397876; PMCID: PMC5029266; DOI: 10.1016/j.yjmcc.2016.07.003;

Cohen RA, Murdoch CE, Watanabe Y, Bolotina VM, Evangelista AM, Haeussler DJ, Smith MD, Mei Y, Tong X, Han J, Behring JB, Bachschmid MM, Matsui R. Endothelial Cell Redox Regulation of Ischemic Angiogenesis. J Cardiovasc Pharmacol. 2016 Jun; 67(6):458-64.View Related Profiles.

Murdoch, Colin
Haeussler, Dagmar
Behring, Jessica
Han, Jingyan
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Bolotina, Victoria
Tong, XiaoYong

PMID: 26927696; PMCID: PMC4899292; DOI: 10.1097/FJC.0000000000000381;

Watanabe Y, Murdoch CE, Sano S, Ido Y, Bachschmid MM, Cohen RA, Matsui R. Glutathione adducts induced by ischemia and deletion of glutaredoxin-1 stabilize HIF-1a and improve limb revascularization. Proc Natl Acad Sci U S A. 2016 May 24; 113(21):6011-6.View Related Profiles.

Murdoch, Colin
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Ido, Yasuo

PMID: 27162359; PMCID: PMC4889374; DOI: 10.1073/pnas.1524198113;

Badarau E, Wang Z, Rathbone DL, Costanzi A, Thibault T, Murdoch CE, El Alaoui S, Bartkeviciute M, Griffin M. Development of Potent and Selective Tissue Transglutaminase Inhibitors: Their Effect on TG2 Function and Application in Pathological Conditions. Chem Biol. 2015 Oct 22; 22(10):1347-61. PMID: 26456735; DOI: 10.1016/j.chembiol.2015.08.013;

Murdoch CE, Bachschmid MM, Matsui R. Regulation of neovascularization by S-glutathionylation via the Wnt5a/sFlt-1 pathway. Biochem Soc Trans. 2014 Dec; 42(6):1665-70.View Related Profiles.

Murdoch, Colin
Bachschmid, Markus
Matsui, Reiko

PMID: 25399587; PMCID: PMC4934611; DOI: 10.1042/BST20140213;

Bastianelli D, Siciliano C, Puca R, Coccia A, Murdoch C, Bordin A, Mangino G, Pompilio G, Calogero A, De Falco E. Influence of Egr-1 in cardiac tissue-derived mesenchymal stem cells in response to glucose variations. Biomed Res Int. 2014; 2014:254793. PMID: 24967343; PMCID: PMC4054710; DOI: 10.1155/2014/254793;

Murdoch CE, Chaubey S, Zeng L, Yu B, Ivetic A, Walker SJ, Vanhoutte D, Heymans S, Grieve DJ, Cave AC, Brewer AC, Zhang M, Shah AM. Endothelial NADPH oxidase-2 promotes interstitial cardiac fibrosis and diastolic dysfunction through proinflammatory effects and endothelial-mesenchymal transition. J Am Coll Cardiol. 2014 Jun 24; 63(24):2734-41. PMID: 24681145; DOI: 10.1016/j.jacc.2014.02.572;

Murdoch CE, Shuler M, Haeussler DJ, Kikuchi R, Bearelly P, Han J, Watanabe Y, Fuster JJ, Walsh K, Ho YS, Bachschmid MM, Cohen RA, Matsui R. Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. J Biol Chem. 2014 Mar 21; 289(12):8633-44.View Related Profiles.

Murdoch, Colin
Haeussler, Dagmar
Han, Jingyan
Fuster Ortuno, Jose
Walsh, Kenneth
Bachschmid, Markus
Matsui, Reiko
Cohen, Richard
Kikuchi, Ryosuke

PMID: 24482236; PMCID: PMC3961686; DOI: 10.1074/jbc.M113.517219;

Drozdov I, Didangelos A, Yin X, Zampetaki A, Abonnenc M, Murdoch C, Zhang M, Ouzounis CA, Mayr M, Tsoka S, Shah AM. Gene network and proteomic analyses of cardiac responses to pathological and physiological stress. Circ Cardiovasc Genet. 2013 Dec; 6(6):588-97. PMID: 24214729; DOI: 10.1161/CIRCGENETICS.113.000063;

Murdoch CE, Alom-Ruiz SP, Wang M, Zhang M, Walker S, Yu B, Brewer A, Shah AM. Role of endothelial Nox2 NADPH oxidase in angiotensin II-induced hypertension and vasomotor dysfunction. Basic Res Cardiol. 2011 Jun; 106(4):527-38. PMID: 21528437; PMCID: PMC3105229; DOI: 10.1007/s00395-011-0179-7;

Ray R, Murdoch CE, Wang M, Santos CX, Zhang M, Alom-Ruiz S, Anilkumar N, Ouattara A, Cave AC, Walker SJ, Grieve DJ, Charles RL, Eaton P, Brewer AC, Shah AM. Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo. Arterioscler Thromb Vasc Biol. 2011 Jun; 31(6):1368-76. PMID: 21415386; DOI: 10.1161/ATVBAHA.110.219238;

Webb IG, Nishino Y, Clark JE, Murdoch C, Walker SJ, Makowski MR, Botnar RM, Redwood SR, Shah AM, Marber MS. Constitutive glycogen synthase kinase-3alpha/beta activity protects against chronic beta-adrenergic remodelling of the heart. Cardiovasc Res. 2010 Aug 1; 87(3):494-503. PMID: 20299330; PMCID: PMC2904659; DOI: 10.1093/cvr/cvq061;

Humphries J, Gossage JA, Modarai B, Burnand KG, Sisson TH, Murdoch C, Smith A. Monocyte urokinase-type plasminogen activator up-regulation reduces thrombus size in a model of venous thrombosis. J Vasc Surg. 2009 Nov; 50(5):1127-34. PMID: 19703758; PMCID: PMC2778796; DOI: 10.1016/j.jvs.2009.06.047;

Kis A, Murdoch C, Zhang M, Siva A, Rodriguez-Cuenca S, Carobbio S, Lukasik A, Blount M, O'Rahilly S, Gray SL, Shah AM, Vidal-Puig A. Defective peroxisomal proliferators activated receptor gamma activity due to dominant-negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice. Eur J Heart Fail. 2009 Jun; 11(6):533-41. PMID: 19395708; PMCID: PMC2686026; DOI: 10.1093/eurjhf/hfp048;

Akki A, Zhang M, Murdoch C, Brewer A, Shah AM. NADPH oxidase signaling and cardiac myocyte function. J Mol Cell Cardiol. 2009 Jul; 47(1):15-22. PMID: 19374908; DOI: 10.1016/j.yjmcc.2009.04.004;

Muthana M, Scott SD, Farrow N, Morrow F, Murdoch C, Grubb S, Brown N, Dobson J, Lewis CE. A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Ther. 2008 Jun; 15(12):902-10. PMID: 18418420; DOI: 10.1038/gt.2008.57;

Sirker A, Zhang M, Murdoch C, Shah AM. Involvement of NADPH oxidases in cardiac remodelling and heart failure. Am J Nephrol. 2007; 27(6):649-60. PMID: 17901689

Murdoch CE, Zhang M, Cave AC, Shah AM. NADPH oxidase-dependent redox signalling in cardiac hypertrophy, remodelling and failure. Cardiovasc Res. 2006 Jul 15; 71(2):208-15. PMID: 16631149

Murdoch CE, Grieve DJ, Cave AC, Looi YH, Shah AM. NADPH oxidase and heart failure. Curr Opin Pharmacol. 2006 Apr; 6(2):148-53. PMID: 16483850

Davis RJ, Murdoch CE, Ali M, Purbrick S, Ravid R, Baxter GS, Tilford N, Sheldrick RL, Clark KL, Coleman RA. EP4 prostanoid receptor-mediated vasodilatation of human middle cerebral arteries. Br J Pharmacol. 2004 Feb; 141(4):580-5. PMID: 14744815; PMCID: PMC1574229

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 42 publications over 19 distinct years, with a maximum of 4 publications in 2014 and 2016 and 2017 and 2023

Bar chart showing 42 publications over 19 distinct years, with a maximum of 4 publications in 2014 and 2016 and 2017 and 2023

Year	Publications
2004	1
2006	2
2007	1
2008	1
2009	3
2010	1
2011	2
2013	1
2014	4
2015	1
2016	4
2017	4
2018	2
2019	3
2020	1
2021	2
2022	2
2023	4
2024	3

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