Keywords
Last Name

Ryosuke Kikuchi

TitlePostdoctoral Fellow
InstitutionBoston University Medical Campus
DepartmentCardiovascular Institute (Whitaker)
Address700 Albany St Ctr for Adv Biomed Res
Boston MA 02118
Phone(617) 414-2390
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Shibata T, Shimizu K, Hirano K, Nakashima F, Kikuchi R, Matsushita T, Uchida K. Adductome-based identification of biomarkers for lipid peroxidation. J Biol Chem. 2017 Mar 24. PMID: 28341743.
    View in: PubMed
  2. Inoue A, Cheng XW, Huang Z, Hu L, Kikuchi R, Jiang H, Piao L, Sasaki T, Itakura K, Wu H, Zhao G, Lei Y, Yang G, Zhu E, Li X, Sato K, Koike T, Kuzuya M. Exercise restores muscle stem cell mobilization, regenerative capacity and muscle metabolic alterations via adiponectin/AdipoR1 activation in SAMP10 mice. J Cachexia Sarcopenia Muscle. 2016 Nov 29. PMID: 27897419.
    View in: PubMed
  3. Yisireyili M, Takeshita K, Hayashi M, Wu H, Uchida Y, Yamamoto K, Kikuchi R, Hao CN, Nakayama T, Cheng XW, Matsushita T, Nakamura S, Murohara T. Dipeptidyl peptidase- IV inhibitor alogliptin improves stress-induced insulin resistance and prothrombotic state in a murine model. Psychoneuroendocrinology. 2016 Nov; 73:186-195. PMID: 27509090.
    View in: PubMed
  4. Nakamura K, Sano S, Fuster JJ, Kikuchi R, Shimizu I, Ohshima K, Katanasaka Y, Ouchi N, Walsh K. Secreted Frizzled-related Protein 5 Diminishes Cardiac Inflammation and Protects the Heart from Ischemia/Reperfusion Injury. J Biol Chem. 2016 Feb 5; 291(6):2566-75. PMID: 26631720.
    View in: PubMed
  5. Hayashi M, Takeshita K, Uchida Y, Yamamoto K, Kikuchi R, Nakayama T, Nomura E, Cheng XW, Matsushita T, Nakamura S, Murohara T. Angiotensin II receptor blocker ameliorates stress-induced adipose tissue inflammation and insulin resistance. PLoS One. 2014; 9(12):e116163. PMID: 25551221.
    View in: PubMed
  6. Kikuchi R, Nakamura K, MacLauchlan S, Ngo DT, Shimizu I, Fuster JJ, Katanasaka Y, Yoshida S, Qiu Y, Yamaguchi TP, Matsushita T, Murohara T, Gokce N, Bates DO, Hamburg NM, Walsh K. An antiangiogenic isoform of VEGF-A contributes to impaired vascularization in peripheral artery disease. Nat Med. 2014 Dec; 20(12):1464-71. PMID: 25362254.
    View in: PubMed
  7. Ngo DT, Farb MG, Kikuchi R, Karki S, Tiwari S, Bigornia SJ, Bates DO, LaValley MP, Hamburg NM, Vita JA, Hess DT, Walsh K, Gokce N. Antiangiogenic actions of vascular endothelial growth factor-A165b, an inhibitory isoform of vascular endothelial growth factor-A, in human obesity. Circulation. 2014 Sep 23; 130(13):1072-80. PMID: 25116954.
    View in: PubMed
  8. Itoh M, Kikuchi R, Uruma T, Tsuji T, Kuroda Y, Watanabe H, Nakamura H, Aoshiba K. All-in-one imaging of polymyositis, lung cancer and its metastatic lesions by fluorine 18 fluorodeoxyglucose positron emission tomography/computed tomography. Acta Reumatol Port. 2014 Jul-Sep; 39(3):283-4. PMID: 25326410.
    View in: PubMed
  9. Yuasa D, Ohashi K, Shibata R, Takeshita K, Kikuchi R, Takahashi R, Kataoka Y, Miyabe M, Joki Y, Kambara T, Uemura Y, Matsuo K, Hayakawa S, Hiramatsu-Ito M, Ito M, Ikeda N, Murohara T, Ouchi N. Association of circulating C1q/TNF-related protein 1 levels with coronary artery disease in men. PLoS One. 2014; 9(6):e99846. PMID: 24945145.
    View in: PubMed
  10. Shimizu I, Aprahamian T, Kikuchi R, Shimizu A, Papanicolaou KN, MacLauchlan S, Maruyama S, Walsh K. Vascular rarefaction mediates whitening of brown fat in obesity. J Clin Invest. 2014 May 1; 124(5):2099-112. PMID: 24713652.
    View in: PubMed
  11. Murdoch CE, Shuler M, Haeussler DJ, Kikuchi R, Bearelly P, Han J, Watanabe Y, Fuster JJ, Walsh K, Ho YS, Bachschmid MM, Cohen RA, Matsui R. Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization. J Biol Chem. 2014 Mar 21; 289(12):8633-44. PMID: 24482236.
    View in: PubMed
  12. Parker-Duffen JL, Nakamura K, Silver M, Kikuchi R, Tigges U, Yoshida S, Denzel MS, Ranscht B, Walsh K. T-cadherin is essential for adiponectin-mediated revascularization. J Biol Chem. 2013 Aug 23; 288(34):24886-97. PMID: 23824191.
    View in: PubMed
  13. Cheng XW, Kikuchi R, Ishii H, Yoshikawa D, Hu L, Takahashi R, Shibata R, Ikeda N, Kuzuya M, Okumura K, Murohara T. Circulating cathepsin K as a potential novel biomarker of coronary artery disease. Atherosclerosis. 2013 May; 228(1):211-6. PMID: 23369704.
    View in: PubMed
  14. Papanicolaou KN, Kikuchi R, Ngoh GA, Coughlan KA, Dominguez I, Stanley WC, Walsh K. Mitofusins 1 and 2 are essential for postnatal metabolic remodeling in heart. Circ Res. 2012 Sep 28; 111(8):1012-26. PMID: 22904094.
    View in: PubMed
  15. Sato B, Yoshikawa D, Ishii H, Kikuchi R, Arima T, Takeshita K, Inoue Y, Suzuki S, Tanaka M, Kumagai S, Matsumoto M, Hayashi M, Ando H, Amano T, Matsubara T, Niwa T, Murohara T. Indoxyl sulfate, a uremic toxin, and carotid intima-media thickness in patients with coronary artery disease. Int J Cardiol. 2013 Feb 20; 163(2):214-6. PMID: 22795243.
    View in: PubMed
  16. Uchida Y, Takeshita K, Yamamoto K, Kikuchi R, Nakayama T, Nomura M, Cheng XW, Egashira K, Matsushita T, Nakamura H, Murohara T. Stress augments insulin resistance and prothrombotic state: role of visceral adipose-derived monocyte chemoattractant protein-1. Diabetes. 2012 Jun; 61(6):1552-61. PMID: 22396205.
    View in: PubMed
  17. Maruyama S, Shibata R, Kikuchi R, Izumiya Y, Rokutanda T, Araki S, Kataoka Y, Ohashi K, Daida H, Kihara S, Ogawa H, Murohara T, Ouchi N. Fat-derived factor omentin stimulates endothelial cell function and ischemia-induced revascularization via endothelial nitric oxide synthase-dependent mechanism. J Biol Chem. 2012 Jan 2; 287(1):408-17. PMID: 22081609.
    View in: PubMed
  18. Shibata R, Ouchi N, Kikuchi R, Takahashi R, Takeshita K, Kataoka Y, Ohashi K, Ikeda N, Kihara S, Murohara T. Circulating omentin is associated with coronary artery disease in men. Atherosclerosis. 2011 Dec; 219(2):811-4. PMID: 21925659.
    View in: PubMed
  19. Horii T, Koike T, Abe Y, Kikuchi R, Unakami H, Iijima K, Imatani A, Ohara S, Shimosegawa T. Two distinct types of cancer of different origin may be mixed in gastroesophageal junction adenocarcinomas in Japan: evidence from direct evaluation of gastric acid secretion. Scand J Gastroenterol. 2011 Jun; 46(6):710-9. PMID: 21446884.
    View in: PubMed
  20. Kikuchi R, Takeshita K, Uchida Y, Kondo M, Cheng XW, Nakayama T, Yamamoto K, Matsushita T, Liao JK, Murohara T. Pitavastatin-induced angiogenesis and arteriogenesis is mediated by Notch1 in a murine hindlimb ischemia model without induction of VEGF. Lab Invest. 2011 May; 91(5):691-703. PMID: 21301413.
    View in: PubMed
  21. Kikuchi R, Jae-Hong P, Takahashi H, Maki M. Disjunct distribution of chloroplast DNA haplotypes in the understory perennial Veratrum album ssp. oxysepalum (Melanthiaceae) in Japan as a result of ancient introgression. New Phytol. 2010 Nov; 188(3):879-91. PMID: 20659302.
    View in: PubMed
  22. Aoyama T, Takeshita K, Kikuchi R, Yamamoto K, Cheng XW, Liao JK, Murohara T. gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice. Biochem Biophys Res Commun. 2009 May 29; 383(2):216-21. PMID: 19345673.
    View in: PubMed
  23. Iijima K, Abe Y, Kikuchi R, Koike T, Ohara S, Sipponen P, Shimosegawa T. Serum biomarker tests are useful in delineating between patients with gastric atrophy and normal, healthy stomach. World J Gastroenterol. 2009 Feb 21; 15(7):853-9. PMID: 19230047.
    View in: PubMed
  24. Furuhata A, Murakami M, Ito H, Gao S, Yoshida K, Sobue S, Kikuchi R, Iwasaki T, Takagi A, Kojima T, Suzuki M, Abe A, Naoe T, Murate T. GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines. Leukemia. 2009 Jul; 23(7):1270-7. PMID: 19212333.
    View in: PubMed
  25. Uchiyama M, Kikuchi R, Konno N, Wakasugi T, Matsuda K. Localization and regulation of a facilitative urea transporter in the kidney of the red-eared slider turtle (Trachemys scripta elegans). J Exp Biol. 2009 Jan; 212(Pt 2):249-56. PMID: 19112144.
    View in: PubMed
  26. Alshehab A, Kobayashi N, Ruiz J, Kikuchi R, Shimamoto S, Ishibashi H. A study on intrabody communication for personal healthcare monitoring system. Telemed J E Health. 2008 Oct; 14(8):851-7. PMID: 18954257.
    View in: PubMed
  27. Murakami M, Ichihara M, Sobue S, Kikuchi R, Ito H, Kimura A, Iwasaki T, Takagi A, Kojima T, Takahashi M, Suzuki M, Banno Y, Nozawa Y, Murate T. RET signaling-induced SPHK1 gene expression plays a role in both GDNF-induced differentiation and MEN2-type oncogenesis. J Neurochem. 2007 Sep; 102(5):1585-94. PMID: 17555548.
    View in: PubMed
  28. Kikuchi R, Sobue S, Murakami M, Ito H, Kimura A, Iwasaki T, Shibayama S, Takagi A, Kojima T, Suzuki M, Banno Y, Nozawa Y, Murate T. Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes. FEBS Lett. 2007 May 1; 581(9):1800-4. PMID: 17433303.
    View in: PubMed
  29. Kikuchi R, Murakami M, Sobue S, Iwasaki T, Hagiwara K, Takagi A, Kojima T, Asano H, Suzuki M, Banno Y, Nozawa Y, Murate T. Ewing's sarcoma fusion protein, EWS/Fli-1 and Fli-1 protein induce PLD2 but not PLD1 gene expression by binding to an ETS domain of 5' promoter. Oncogene. 2007 Mar 15; 26(12):1802-10. PMID: 16964281.
    View in: PubMed
  30. Yamada Y, Banno Y, Yoshida H, Kikuchi R, Akao Y, Murate T, Nozawa Y. Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation. Arch Med Res. 2006 Aug; 37(6):696-9. PMID: 16824927.
    View in: PubMed
  31. Yajima Y, Takahashi N, Miyazaki A, Kikuchi R, Kakisaka K, Oikawa K, Sugawara K, Eda Y, Naganuma H, Unagami M. [Prevalence of non-alcoholic steatohepatitis (NASH) among biopsied cases of a urban hospital in Japan: significance of measurement of serum ferritin in the detection of NASH]. Nihon Shokakibyo Gakkai Zasshi. 2006 May; 103(5):515-22. PMID: 16734257.
    View in: PubMed
  32. Kikuchi R, Noguchi T, Takeno S, Funada Y, Moriyama H, Uchida Y. Nuclear BAG-1 expression reflects malignant potential in colorectal carcinomas. Br J Cancer. 2002 Nov 4; 87(10):1136-9. PMID: 12402153.
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  33. Takeno S, Noguchi T, Kikuchi R, Sato T, Uchida Y, Yokoyama S. Analysis of early (pT1) gastric cancer with submucosal invasion: surgical management and possibility to schedule less invasive surgery. Ann Surg Oncol. 2001 Aug; 8(7):605-10. PMID: 11508623.
    View in: PubMed
  34. Takeno S, Noguchi T, Kikuchi R, Wada S, Sato T, Uchida Y. Immunohistochemical study of leukocyte infiltration and expression of hsp70 in esophageal squamous cell carcinoma. Oncol Rep. 2001 May-Jun; 8(3):585-90. PMID: 11295085.
    View in: PubMed
  35. Takeno S, Noguchi T, Kikuchi R, Sato T, Uchida Y, Yokoyama S. Analysis of the survival period in resectable stage IV gastric cancer. Ann Surg Oncol. 2001 Apr; 8(3):215-21. PMID: 11314937.
    View in: PubMed
  36. Takeno S, Noguchi T, Takahashi Y, Kikuchi R, Uchida Y, Yokoyama S. Immunohistochemical and clinicopathologic analysis of response to neoadjuvant therapy for esophageal squamous cell carcinoma. Dis Esophagus. 2001; 14(2):149-54. PMID: 11553227.
    View in: PubMed
  37. Maruyama R, Noguchi T, Takano M, Takagi K, Morita N, Kikuchi R, Uchida Y. Usefulness of magnetic resonance imaging for diagnosing deep anorectal abscesses. Dis Colon Rectum. 2000 Oct; 43(10 Suppl):S2-5. PMID: 11052470.
    View in: PubMed
  38. Chaki O, Yoshikata I, Kikuchi R, Nakayama M, Uchiyama Y, Hirahara F, Gorai I. The predictive value of biochemical markers of bone turnover for bone mineral density in postmenopausal Japanese women. J Bone Miner Res. 2000 Aug; 15(8):1537-44. PMID: 10934652.
    View in: PubMed
  39. Kikuchi R, Noguchi T, Takeno S, Kubo N, Uchida Y. Immunohistochemical detection of membrane-type-1-matrix metalloproteinase in colorectal carcinoma. Br J Cancer. 2000 Jul; 83(2):215-8. PMID: 10901373.
    View in: PubMed
  40. Yoshimura K, Fujii J, Yutsudo T, Kikuchi R, Soejima T, Shirahata S, Yoshida S. No direct effects of Shiga toxin 1 and 2 on the aggregation of human platelets in vitro. Thromb Haemost. 1998 Sep; 80(3):529-30. PMID: 9759646.
    View in: PubMed
  41. Gorai I, Taguchi Y, Chaki O, Kikuchi R, Nakayama M, Yang BC, Yokota S, Minaguchi H. Serum soluble interleukin-6 receptor and biochemical markers of bone metabolism show significant variations during the menstrual cycle. J Clin Endocrinol Metab. 1998 Feb; 83(2):326-32. PMID: 9467535.
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  42. Nakagawa T, Sekizawa K, Arai H, Kikuchi R, Manabe K, Sasaki H. High incidence of pneumonia in elderly patients with basal ganglia infarction. Arch Intern Med. 1997 Feb 10; 157(3):321-4. PMID: 9040300.
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  43. Watanabe Y, Kiriyama M, Ito R, Kikuchi R, Mizufune Y, Nomura H, Miyazaki M, Matsumoto M. Pharmacodynamics and pharmacokinetics of recombinant human granulocyte colony-stimulating factor (rhG-CSF) after administration of a rectal dosage vehicle. Biol Pharm Bull. 1996 Aug; 19(8):1059-63. PMID: 8874816.
    View in: PubMed
  44. Watanabe Y, Kiriyama M, Oe J, Kikuchi R, Mizufune Y, Matsumoto M. Pharmacodynamic activity (leukopoietic effect) of recombinant human granulocyte colony-stimulating factor (rhG-CSF) after rectal administration in rabbits with leukopenia induced by cyclophosphamide. Biol Pharm Bull. 1996 Aug; 19(8):1064-7. PMID: 8874817.
    View in: PubMed
  45. Kikuchi R, Takano M, Takagi K, Fujimoto N, Nozaki R, Fujiyoshi T, Uchida Y. Management of early invasive colorectal cancer. Risk of recurrence and clinical guidelines. Dis Colon Rectum. 1995 Dec; 38(12):1286-95. PMID: 7497841.
    View in: PubMed
  46. Watanabe Y, Kikuchi R, Kiriyama M, Nakagawa K, Oe J, Nomura H, Maruyama K, Matsumoto M. Increase in total blood leukocyte count following intranasal administration of recombinant human granulocyte colony-stimulating factor (rhG-CSF) in rabbits with cyclophosphamide-induced leukopenia. Biol Pharm Bull. 1995 Aug; 18(8):1084-8. PMID: 8535401.
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  47. Kikuchi R, Kikuchi K, Hildebrandt J, Yanai M, Sekizawa K, Sasaki H. Dependence of collateral and small airway resistances of CO2 and volume in dog lobes. Respir Physiol. 1995 Jun; 100(3):245-52. PMID: 7481114.
    View in: PubMed
  48. Watanabe Y, Matsumoto Y, Kikuchi R, Kiriyama M, Nakagawa K, Nomura H, Maruyama K, Matsumoto M. Pharmacokinetics and pharmacodynamics of recombinant human granulocyte colony-stimulating factor (rhG-CSF) following intranasal administration in rabbits. J Drug Target. 1995; 3(3):231-8. PMID: 8705257.
    View in: PubMed
  49. Kikuchi R, Watabe N, Konno T, Mishina N, Sekizawa K, Sasaki H. High incidence of silent aspiration in elderly patients with community-acquired pneumonia. Am J Respir Crit Care Med. 1994 Jul; 150(1):251-3. PMID: 8025758.
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  50. Kikuchi R, Kikuchi K, Hildebrandt J, Sekizawa K, Yamaya M, Sasaki H. Bronchomotor agents and hysteresis of collateral resistance in dog lobe. Respir Physiol. 1994 May; 96(2-3):127-37. PMID: 8059079.
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  51. Watanabe Y, Matsumoto Y, Yamaguchi M, Kikuchi R, Takayama K, Nomura H, Maruyama K, Matsumoto M. Absorption of recombinant human granulocyte colony-stimulating factor (rhG-CSF) and blood leukocyte dynamics following intranasal administration in rabbits. Biol Pharm Bull. 1993 Jan; 16(1):93-5. PMID: 7690293.
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  52. Kikuchi R, Hildebrandt J, Sekizawa K, Sasaki H, Takishima T. Influence of lung volume history and increased surface forces on collateral resistance. Respir Physiol. 1992 Jul; 89(1):15-25. PMID: 1518984.
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  53. Kodama H, Sasaki K, Mizobuchi N, Kikuchi R. Contents of cystathionine and taurine in various cerebellar regions of DL-propargylglycine-treated rats. J Neurochem. 1988 Oct; 51(4):1046-8. PMID: 3418343.
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  54. Suzuki S, Kikuchi R. [Klippel-Trenaunay-Weber syndrome]. Rinsho Hoshasen. 1970 Nov; 15(11):834-40. PMID: 5203501.
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  55. Koyanagi T, Hareyama S, Kikuchi R, Takanohashi T, Oikawa K. Effect of administration of thiamine, riboflavin, ascorbic acid and vitamin A to students on their pantothenic acid contents in serum and urine. Tohoku J Exp Med. 1969 Aug; 98(4):357-62. PMID: 5346207.
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