Noyan Gokce, MD
Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Tufts University School of Medicine



My area of expertise is studying disease mechanisms in vascular biology. My recent research has focused on the effect of obesity and inflammation on vascular dysfunction. I have received two R01 grants to support this line of investigation and have additionally received a 5-year PPG project grant with Dr. Ken Walsh. I also have extensive expertise in echocardigraphy and currently collaborate with several investigators in the Department of Medicine.

Active Staff Privileges
Boston Medical Center
Medicine



2011-2011 Department of Cardiology : I received the 2011 Excellence in Clinical Teaching Award from the Section of Cardiology at Boston M
2010-2010 Department of Evans/Medicine : Work presented from our laboratory by Dr. Melissa Farb received FIRST PRIZE in clinical research in


Adipose Inflammation, Mitochondrial & Endothelial Phenotypes in Obesity
07/01/2016 - 06/30/2018 (PI)
NIH/National Heart, Lung, and Blood Inst
4R01HL114675-05

Anti-Angiogenic Mechanisms in Human Obesity
11/14/2014 - 10/31/2017 (PI)
NIH/National Heart, Lung, and Blood Inst
5R01HL126141-03

Adipose Inflammation, Mitochondrial Function & Endothelial Phenotypes in Obesity
07/05/2012 - 06/30/2016 (PI)
NIH/National Heart, Lung, and Blood Inst
5R01HL114675-04

Contribution of Myeloperoxidasae Activity to Endothelial Dysfunction in Adipose Tissue Arterioles Isolated from Obese Human Subjects
07/01/2012 - 06/30/2015 (PI)
Pfizer, Inc.


Inflammation and Vascular Dysfunction in Obesity
02/20/2007 - 01/31/2013 (PI)
NIH/National Heart, Lung, and Blood Inst
5R01HL084213-05


Obesity, Adipocytokines, and Endothelial Dysfunction
08/15/2003 - 07/31/2009 (PI)
NIH-NHLBI

Endothelial Dysfunction
09/01/2000 - 07/31/2006 (PI)
NIH-NHLBI

Predictive value of Endothelial Disfunction
07/01/2003 - 06/30/2005 (PI)
American Society of Echocardiography

Oxidative Stress And Endotheli
05/30/1998 - 05/29/2001 (PI)
NIH-NHLBI



Yr Title Project-Sub Proj Pubs
2017 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-03 4
2016 Anti-Angiogenic Mechanisms in Human Obesity 5R01HL126141-02 4
2016 Adipose inflammation, mitochondrial function & endothelial phenotypes in obesity 4R01HL114675-05 16
2015 Anti-Angiogenic Mechanisms in Human Obesity 1R01HL126141-01 4
2015 Adipose inflammation, mitochondrial function &endothelial phenotypes in obesity 5R01HL114675-04 16
2015 ADIPOSE REMODELING &VASCULAR PHENOTYPES IN OBESITY 5P01HL081587-10-7345 150
2014 Adipose inflammation, mitochondrial function &endothelial phenotypes in obesity 5R01HL114675-03 16
2014 ADIPOSE REMODELING &VASCULAR PHENOTYPES IN OBESITY 5P01HL081587-09-7345 150
2013 Adipose inflammation, mitochondrial function &endothelial phenotypes in obesity 5R01HL114675-02 16
2013 ADIPOSE REMODELING &VASCULAR PHENOTYPES IN OBESITY 5P01HL081587-08-7345 150
Showing 10 of 32 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Farb MG, Park SY, Karki S, Gokce N. Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy. J Vis Exp. 2017 Sep 29; (127).View Related Profiles. PMID: 28994775.
  2. Zuriaga MA, Fuster JJ, Gokce N, Walsh K. Humans and Mice Display Opposing Patterns of "Browning" Gene Expression in Visceral and Subcutaneous White Adipose Tissue Depots. Front Cardiovasc Med. 2017; 4:27.View Related Profiles. PMID: 28529941.
  3. Karki S, Ngo DTM, Farb MG, Park SY, Saggese SM, Hamburg NM, Carmine B, Hess DT, Walsh K, Gokce N. WNT5A regulates adipose tissue angiogenesis via antiangiogenic VEGF-A165b in obese humans. Am J Physiol Heart Circ Physiol. 2017 Jul 01; 313(1):H200-H206.View Related Profiles. PMID: 28411232; DOI: 10.1152/ajpheart.00776.2016;.
  4. Fetterman JL, Holbrook M, Westbrook DG, Brown JA, Feeley KP, Bretón-Romero R, Linder EA, Berk BD, Weisbrod RM, Widlansky ME, Gokce N, Ballinger SW, Hamburg NM. Mitochondrial DNA damage and vascular function in patients with diabetes mellitus and atherosclerotic cardiovascular disease. Cardiovasc Diabetol. 2016 Mar 31; 15:53.View Related Profiles. PMID: 27036979; PMCID: PMC4818501; DOI: 10.1186/s12933-016-0372-y;.
  5. Fetterman JL, Holbrook M, Flint N, Feng B, Bret?n-Romero R, Linder EA, Berk BD, Duess MA, Farb MG, Gokce N, Shirihai OS, Hamburg NM, Vita JA. Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling. Atherosclerosis. 2016 Apr; 247:207-17.View Related Profiles. PMID: 26926601; PMCID: PMC4913892; DOI: 10.1016/j.atherosclerosis.2016.01.043;.
  6. Bretón-Romero R, Feng B, Holbrook M, Farb MG, Fetterman JL, Linder EA, Berk BD, Masaki N, Weisbrod RM, Inagaki E, Gokce N, Fuster JJ, Walsh K, Hamburg NM. Endothelial Dysfunction in Human Diabetes Is Mediated by Wnt5a-JNK Signaling. Arterioscler Thromb Vasc Biol. 2016 Mar; 36(3):561-9.View Related Profiles. PMID: 26800561; PMCID: PMC4913891; DOI: 10.1161/ATVBAHA.115.306578;.
  7. Tampakakis E, Tabit CE, Holbrook M, Linder EA, Berk BD, Frame AA, Bretón-Romero R, Fetterman JL, Gokce N, Vita JA, Hamburg NM. Intravenous Lipid Infusion Induces Endoplasmic Reticulum Stress in Endothelial Cells and Blood Mononuclear Cells of Healthy Adults. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles. PMID: 26755554; PMCID: PMC4859375; DOI: 10.1161/JAHA.115.002574;.
  8. Karki S, Farb MG, Myers S, Apovian C, Hess DT, Gokce N. Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans. Mediators Inflamm. 2015; 2015:106237.View Related Profiles. PMID: 26663986; DOI: 10.1155/2015/106237;.
  9. Wang YC, Liang CS, Gopal DM, Ayalon N, Donohue C, Santhanakrishnan R, Sandhu H, Perez AJ, Downing J, Gokce N, Colucci WS, Ho JE. Preclinical Systolic and Diastolic Dysfunctions in Metabolically Healthy and Unhealthy Obese Individuals. Circ Heart Fail. 2015 Sep; 8(5):897-904.View Related Profiles. PMID: 26175540; PMCID: PMC4573845; DOI: 10.1161/CIRCHEARTFAILURE.114.002026;.
  10. Karki S, Farb MG, Ngo DT, Myers S, Puri V, Hamburg NM, Carmine B, Hess DT, Gokce N. Forkhead box O-1 modulation improves endothelial insulin resistance in human obesity. Arterioscler Thromb Vasc Biol. 2015 Jun; 35(6):1498-506.View Related Profiles. PMID: 25908760; PMCID: PMC4441602; DOI: 10.1161/ATVBAHA.114.305139;.
Showing 10 of 77 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 77 publications over 21 distinct years, with a maximum of 8 publications in 2003

YearPublications
19891
19961
19982
19993
20001
20015
20024
20038
20042
20053
20075
20083
20093
20104
20113
20126
20134
20146
20156
20164
20173
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Cardiovascular Diseases
Echocardiography
Obesity

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