Victoria Bolotina, PhD
Professor
Boston University School of Medicine
Dept of Medicine
Vascular Biology

PhD, Moscow State University



I am an expert in Calcium signaling and ion channels in a wide spectrum of cell types.

Research Professor
Boston University School of Medicine
Physiology & Biophysics


Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences


Boston Medical Center




Multidisciplinary Training in Cardiovascular Research
07/01/2016 - 06/30/2018 (PI)
NIH/National Heart, Lung, and Blood Inst
3T32HL007224-41A1S1

Multidisciplinary Training in Cardiovascular Research
07/01/1976 - 06/30/2016 (PI)
NIH/National Heart, Lung, and Blood Inst
3T32HL007224-40S1


PARK14/Calcium signaling as a novel biomarker for Parkinson disease
08/15/2017 - 07/31/2019 (PI)
NIH-NINDS
1R21NS103142-01

Park14-dependent SOCE and sporadic PD
01/01/2017 - 12/31/2017 (PI)
Michael J. Fox Foundation

Servier Contract Research Program
10/01/2014 - 09/30/2017 (PI)
Servier

PARK-14-dependent SOCE and sporadic PD
01/01/2015 - 06/30/2016 (PI)
Michael J. Fox Foundation

Ion channels and calcium regulation in vascular SMC function
05/01/2010 - 04/30/2015 (PI)
NIH-NHLBI

PARK 14: Validation of a mouse model of age-dependent PD
05/15/2013 - 05/14/2014 (PI)
Michael J. Fox Foundation

Store-operated Ca entry and iPLA2 in vascular SMC
01/01/2009 - 12/31/2013 (PI)
NIH-NHLBI

Calcium Influx Factor
08/01/2009 - 07/31/2011 (PI)
NIH-NHLBI

Nitric Oxide And Ion Channels
08/21/1998 - 04/30/2010 (PI)
NIH-NHLBI

Store Operatied Ca2 Influx & iPLA2 in Vascular
06/13/2003 - 05/31/2008 (PI)
NIH-NHLBI

Showing 10 of 12 results. Show All Results


Yr Title Project-Sub Proj Pubs
2017 PARK14/Calcium signaling as a novel biomarker for Parkinson disease 1R21NS103142-01
2017 Multidisciplinary Training in Cardiovascular Research 3T32HL007224-40S1 116
2017 Multidisciplinary Training in Cardiovascular Research 3T32HL007224-41A1S1 116
2016 Multidisciplinary Training in Cardiovascular Research 2T32HL007224-41A1 116
2014 Multidisciplinary Training in Cardiovascular Research 5T32HL007224-39 116
2013 Ion channels and calcium regulation in vascular SMC function 5R01HL054150-16 24
2013 Multidisciplinary Training in Cardiovascular Research 5T32HL007224-38 116
2012 Store-Operated Ca entry and iPLA2 in vascular SMC 5R01HL071793-08 14
2012 Ion channels and calcium regulation in vascular SMC function 5R01HL054150-15 24
2012 Multidisciplinary Training in Cardiovascular Research 5T32HL007224-37 116
Showing 10 of 37 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Cohen RA, Murdoch CE, Watanabe Y, Bolotina VM, Evangelista AM, Haeussler DJ, Smith MD, Mei Y, Tong X, Han J, Behring JB, Bachschmid MM, Matsui R. Endothelial Cell Redox Regulation of Ischemic Angiogenesis. J Cardiovasc Pharmacol. 2016 Jun; 67(6):458-64.View Related Profiles. PMID: 26927696; PMCID: PMC4899292; DOI: 10.1097/FJC.0000000000000381;.
  2. Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson''s disease. Nat Commun. 2016; 7:10332.View Related Profiles. PMID: 26755131; PMCID: PMC4729940; DOI: 10.1038/ncomms10332;.
  3. Thompson MD, Mei Y, Weisbrod RM, Silver M, Shukla PC, Bolotina VM, Cohen RA, Tong X. Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery. J Biol Chem. 2014 Jul 18; 289(29):19907-16.View Related Profiles. PMID: 24920669; PMCID: PMC4106311; DOI: 10.1074/jbc.M114.554451;.
  4. Evangelista AM, Thompson MD, Bolotina VM, Tong X, Cohen RA. Nox4- and Nox2-dependent oxidant production is required for VEGF-induced SERCA cysteine-674 S-glutathiolation and endothelial cell migration. Free Radic Biol Med. 2012 Dec 15; 53(12):2327-34.View Related Profiles. PMID: 23089226; PMCID: PMC3568680; DOI: 10.1016/j.freeradbiomed.2012.10.546;.
  5. Schäfer C, Rymarczyk G, Ding L, Kirber MT, Bolotina VM. Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration. J Biol Chem. 2012 Nov 23; 287(48):40745-57.View Related Profiles. PMID: 23043102; PMCID: PMC3504787; DOI: 10.1074/jbc.M112.407155;.
  6. Evangelista AM, Thompson MD, Weisbrod RM, Pimental DR, Tong X, Bolotina VM, Cohen RA. Redox regulation of SERCA2 is required for vascular endothelial growth factor-induced signaling and endothelial cell migration. Antioxid Redox Signal. 2012 Oct 15; 17(8):1099-108.View Related Profiles. PMID: 22472004; PMCID: PMC3423867; DOI: 10.1089/ars.2011.4022;.
  7. Bolotina VM. Orai1, STIM1, and iPLA2ß determine arterial vasoconstriction. Arterioscler Thromb Vasc Biol. 2012 May; 32(5):1066-7. PMID: 22517361; DOI: 10.1161/ATVBAHA.112.245449;.
  8. Gwozdz T, Dutko-Gwozdz J, Schafer C, Bolotina VM. Overexpression of Orai1 and STIM1 proteins alters regulation of store-operated Ca2+ entry by endogenous mediators. J Biol Chem. 2012 Jun 29; 287(27):22865-72. PMID: 22549787; PMCID: PMC3391152; DOI: 10.1074/jbc.M112.356626;.
  9. Yang B, Gwozdz T, Dutko-Gwozdz J, Bolotina VM. Orai1 and Ca2+-independent phospholipase A2 are required for store-operated Icat-SOC current, Ca2+ entry, and proliferation of primary vascular smooth muscle cells. Am J Physiol Cell Physiol. 2012 Mar 1; 302(5):C748-56. PMID: 22094335; PMCID: PMC3774541; DOI: 10.1152/ajpcell.00312.2011;.
  10. Gwozdz T, Dutko-Gwozdz J, Zarayskiy V, Peter K, Bolotina VM. How strict is the correlation between STIM1 and Orai1 expression, puncta formation, and ICRAC activation? Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1133-40. PMID: 18768920; PMCID: PMC2584986; DOI: 10.1152/ajpcell.00306.2008;.
Showing 10 of 40 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 40 publications over 22 distinct years, with a maximum of 5 publications in 2012

YearPublications
19811
19841
19871
19892
19911
19921
19941
19971
19994
20002
20011
20021
20032
20044
20051
20061
20072
20084
20111
20125
20141
20162
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

calcium homeostasis
ion channels
signaling
Vascular smooth muscle
Contact for Mentoring:


650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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