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Last Name

Stephen Whelan, PhD

TitleInstructor
InstitutionBoston University School of Medicine
DepartmentBiochemistry
Address670 Albany St Biosquare III
Boston MA 02118
Phone(617) 638-6769
ORCID ORCID Icon0000-0002-5439-6501
 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Ma J, Banerjee P, Whelan SA, Liu T, Wei AC, Ramirez-Correa G, McComb ME, Costello CE, O'Rourke B, Murphy A, Hart GW. Comparative Proteomics Reveals Dysregulated Mitochondrial O-GlcNAcylation in Diabetic Hearts. J Proteome Res. 2016 Jul 01; 15(7):2254-64. PMID: 27213235.
    View in: PubMed
  2. Zhang Z, Costa FC, Tan EP, Bushue N, DiTacchio L, Costello CE, McComb ME, Whelan SA, Peterson KR, Slawson C. O-Linked N-Acetylglucosamine (O-GlcNAc) Transferase and O-GlcNAcase Interact with Mi2ß Protein at the A?-Globin Promoter. J Biol Chem. 2016 Jul 22; 291(30):15628-40. PMID: 27231347.
    View in: PubMed
  3. Lucena MC, Carvalho-Cruz P, Donadio JL, Oliveira IA, de Queiroz RM, Marinho-Carvalho MM, Sola-Penna M, de Paula IF, Gondim KC, McComb ME, Costello CE, Whelan SA, Todeschini AR, Dias WB. Epithelial Mesenchymal Transition Induces Aberrant Glycosylation through Hexosamine Biosynthetic Pathway Activation. J Biol Chem. 2016 Jun 17; 291(25):12917-29. PMID: 27129262.
    View in: PubMed
  4. Yao C, Behring JB, Shao D, Sverdlov AL, Whelan SA, Elezaby A, Yin X, Siwik DA, Seta F, Costello CE, Cohen RA, Matsui R, Colucci WS, McComb ME, Bachschmid MM. Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins. PLoS One. 2015; 10(12):e0144025. PMID: 26642319.
    View in: PubMed
  5. Vasconcelos-Dos-Santos A, Oliveira IA, Lucena MC, Mantuano NR, Whelan SA, Dias WB, Todeschini AR. Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer. Front Oncol. 2015; 5:138. PMID: 26161361.
    View in: PubMed
  6. de Souza EE, Meirelles GV, Godoy BB, Perez AM, Smetana JH, Doxsey SJ, McComb ME, Costello CE, Whelan SA, Kobarg J. Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6. J Proteome Res. 2014 Sep 5; 13(9):4074-90. PMID: 25093993.
    View in: PubMed
  7. Chin RM, Fu X, Pai MY, Vergnes L, Hwang H, Deng G, Diep S, Lomenick B, Meli VS, Monsalve GC, Hu E, Whelan SA, Wang JX, Jung G, Solis GM, Fazlollahi F, Kaweeteerawat C, Quach A, Nili M, Krall AS, Godwin HA, Chang HR, Faull KF, Guo F, Jiang M, Trauger SA, Saghatelian A, Braas D, Christofk HR, Clarke CF, Teitell MA, Petrascheck M, Reue K, Jung ME, Frand AR, Huang J. The metabolite a-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014 Jun 19; 510(7505):397-401. PMID: 24828042.
    View in: PubMed
  8. Behring JB, Kumar V, Whelan SA, Chauhan P, Siwik DA, Costello CE, Colucci WS, Cohen RA, McComb ME, Bachschmid MM. Does reversible cysteine oxidation link the Western diet to cardiac dysfunction? FASEB J. 2014 May; 28(5):1975-87. PMID: 24469991.
    View in: PubMed
  9. Spencer JL, Bhatia VN, Whelan SA, Costello CE, McComb ME. STRAP PTM: Software Tool for Rapid Annotation and Differential Comparison of Protein Post-Translational Modifications. Curr Protoc Bioinformatics. 2013 Dec; 44:13.22.1-36. PMID: 25422678.
    View in: PubMed
  10. Whelan SA, He J, Lu M, Souda P, Saxton RE, Faull KF, Whitelegge JP, Chang HR. Mass spectrometry (LC-MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid. J Proteome Res. 2012 Oct 5; 11(10):5034-45. PMID: 22934887.
    View in: PubMed
  11. He J, Whelan SA, Lu M, Shen D, Chung DU, Saxton RE, Faull KF, Whitelegge JP, Chang HR. Proteomic-based biosignatures in breast cancer classification and prediction of therapeutic response. Int J Proteomics. 2011; 2011:896476. PMID: 22110952.
    View in: PubMed
  12. Kealey CP, Whelan SA, Chun YJ, Soojung CH, Tulloch AW, Mohanchandra KP, Di Carlo D, Levi DS, Carman GP, Rigberg DA. In vitro hemocompatibility of thin film nitinol in stenotic flow conditions. Biomaterials. 2010 Dec; 31(34):8864-71. PMID: 20810163.
    View in: PubMed
  13. Lu M, Whelan SA, He J, Saxton RE, Faull KF, Whitelegge JP, Chang HR. Hydrophobic Proteome Analysis of Triple Negative and Hormone-Receptor-Positive-Her2-Negative Breast Cancer by Mass Spectrometer. Clin Proteomics. 2010 Sep; 6(3):93-103. PMID: 20930921.
    View in: PubMed
  14. Lu M, Whitelegge JP, Whelan SA, He J, Saxton RE, Faull KF, Chang HR. Hydrophobic Fractionation Enhances Novel Protein Detection by Mass Spectrometry in Triple Negative Breast Cancer. J Proteomics Bioinform. 2010 Jan 22; 3(2):1-10. PMID: 20596302.
    View in: PubMed
  15. Whelan SA, Dias WB, Thiruneelakantapillai L, Lane MD, Hart GW. Regulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytes. J Biol Chem. 2010 Feb 19; 285(8):5204-11. PMID: 20018868.
    View in: PubMed
  16. Whelan SA, Lu M, He J, Yan W, Saxton RE, Faull KF, Whitelegge JP, Chang HR. Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers. J Proteome Res. 2009 Aug; 8(8):4151-60. PMID: 19522481.
    View in: PubMed
  17. Graham DR, Mitsak MJ, Elliott ST, Chen D, Whelan SA, Hart GW, Van Eyk JE. Two-dimensional gel-based approaches for the assessment of N-Linked and O-GlcNAc glycosylation in human and simian immunodeficiency viruses. Proteomics. 2008 Dec; 8(23-24):4919-30. PMID: 19072736.
    View in: PubMed
  18. Whelan SA, Lane MD, Hart GW. Regulation of the O-linked beta-N-acetylglucosamine transferase by insulin signaling. J Biol Chem. 2008 Aug 1; 283(31):21411-7. PMID: 18519567.
    View in: PubMed
  19. Tao GZ, Kirby C, Whelan SA, Rossi F, Bi X, MacLaren M, Gentalen E, O'Neill RA, Hart GW, Omary MB. Reciprocal keratin 18 Ser48 O-GlcNAcylation and Ser52 phosphorylation using peptide analysis. Biochem Biophys Res Commun. 2006 Dec 22; 351(3):708-12. PMID: 17084817.
    View in: PubMed
  20. Whelan SA, Hart GW. Identification of O-GlcNAc sites on proteins. Methods Enzymol. 2006; 415:113-33. PMID: 17116471.
    View in: PubMed
  21. Stephen A. Whelan and Gerald W. Hart. O-linked N-acetylglucosamine (O-GlcNAc). Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. http://onlinelibrary.wiley.com/login-options. 2005.
    View in: External Website
  22. Whelan SA, Hart GW. Proteomic approaches to analyze the dynamic relationships between nucleocytoplasmic protein glycosylation and phosphorylation. Circ Res. 2003 Nov 28; 93(11):1047-58. PMID: 14645135.
    View in: PubMed
  23. Wells L, Whelan SA, Hart GW. O-GlcNAc: a regulatory post-translational modification. Biochem Biophys Res Commun. 2003 Mar 14; 302(3):435-41. PMID: 12615051.
    View in: PubMed
  24. Acevedo-Duncan M, Patel R, Whelan S, Bicaku E. Human glioma PKC-iota and PKC-betaII phosphorylate cyclin-dependent kinase activating kinase during the cell cycle. Cell Prolif. 2002 Feb; 35(1):23-36. PMID: 11856176.
    View in: PubMed
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