An iPSC-derived human organoid based model of intestinal filovirus infection03/01/2024 - 02/28/2025 (Key Person / Mentor)
NIH/National Institute of Allergy & Infectious Diseases1F31AI183803-01
Functional T cells from iPSCs Using Chimeric Antigen Receptors06/01/2019 - 05/31/2021 (Key Person / Mentor)
PI:
Dar M. Heinze, PhDNIH/National Heart, Lung, and Blood Institute5F32HL149605-02
Modeling prion diseases using human iPSC-derived neurons03/15/2019 - 02/28/2021 (Multi-PI)
PI:
Gustavo Mostoslavsky, MD, PhDNIH/National Institute of Neurological Disorders & Stroke1R21NS111499-01
A National Resource for Lung disease-specific IPS cells08/15/2014 - 04/30/2020 (Multi-PI)
PI:
Gustavo Mostoslavsky, MD, PhDNIH/National Heart, Lung, and Blood Institute5R24HL123828-05
Antiviral responses in iPSC-derived human primary cells to Ebola virus infection06/30/2016 - 05/31/2019 (Multi-PI)
PI:
Gustavo Mostoslavsky, MD, PhDNIH/National Institute of Allergy & Infectious Diseases5R21AI126457-02
Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells07/05/2011 - 06/30/2017 (Multi-PI)
PI:
Gustavo Mostoslavsky, MD, PhDNIH/National Heart, Lung, and Blood Institute5U01HL107443-05
Globin Gene Expression in Sickle Cell Genotype-Specific iPS cells07/05/2011 - 06/30/2016 (Co-Investigator)
PI:
Martin H. Steinberg, MDNIH/National Heart, Lung, and Blood Institute1U01HL107443-01
Reverse genetic tools and novel models of henipavirus infection10/28/2022 - 09/30/2025 (PI)
Trustees of Boston University, BUMC Bill & Melinda Gates
Synergistic Mechanisms of Inflammasome Activation in Microglia by Opiates and Chronic HIV infection07/15/2020 - 04/30/2025 (PI)
Trustees of Boston University, BUMC National Institute o
Uncovering the RNA regulatory mechanisms driving pathogenicity of mass-casualty viruses: Merging the technologies of RNA biology and enhanced biosafety to create the next generation of broad spectrum, RNA-based antiviral therapies10/01/2022 - 09/30/2024 (PI)
Howard Hughes Medical Institute
Pre notification Epigenetic Scars: Understanding DSB repair from pathway choice to long term effects and their consequences.07/01/2023 - 06/30/2024 (PI)
Ben Gurion University of the Negev Euro Research Coun
Dissecting the mechanisms of intestinal epithelial injury by Ebola virus using iPSC-derived intestinal organoids07/05/2022 - 06/30/2024 (PI)
National Institute of Allergy and Infectious Diseases/NIH/DHHS1R21AI167369-01A1
T cell function by targeting HER2 positive cancer cells in vitro01/01/2021 - 12/31/2023 (PI)
Clade Therapeutics
Dissecting the mechanisms of intestinal epithelial injury by Ebola virus using iPSC-derived intestinal organoids07/05/2022 - 07/04/2023 (PI)
National Institute of Allergy and Infectious Diseases/NIH/DHHS1R21AI167369-01A1
Modeling Prion Diseases Using Human iPSC-derived Neurons03/15/2020 - 02/28/2021 (PI)
Trustees of Boston University, BUMC National Institute o
Modeling Creutzfeldt-Jakob Disease Using Human iPSC-derived Neurons01/15/2020 - 01/14/2021 (PI)
Creutzfeldt-Jakob Disease Foundation, Inc.
Distinct Functional Outcomes or BCR/TLR7 and BCR/TLR9 Co-engagement03/12/2015 - 02/29/2020 (PI)
UMASS Worcester NIH-NIAMS
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Engineering a 3D human neurovascular unit for investigating and countering neuroinflammatory mechanisms of HIV09/30/2017 - 08/31/2019 (PI)
Trustees of Boston University,CRC National Institutes
Antiviral responses in iPSC-derived human primary cells to Ebola Virus infection06/30/2016 - 05/31/2019 (PI)
Trustees of Boston University,CRC National Institute o
Targeting Sequencing and Functional Evaluation of Mutations in Schizophrenia05/01/2014 - 02/28/2019 (PI)
Northshore University Health System NIH-NIMH5R01MH100915-04
The Role of SIRT6 and Metabolism in APC Mediated Tumorigenesis01/01/2014 - 12/31/2018 (PI)
Mass General Hosp NIH-NCI
iPSC-derived Repair Fibroblasts to Heal Refractory Venous Ulcers08/01/2012 - 07/31/2013 (PI)
Tufts University NIH-NIDDK
Characterization of human blood and lung progenitors derived from iPS cells free of reprogramming tr09/30/2009 - 08/31/2011 (PI)
Trustees of Boston University NIH-NHLBI
Study of Rag 1 hypomorphic mice and their rescue by lentiviral gene transfer09/30/2008 - 08/31/2011 (PI)
NIH-NICHD5R21 HD060308-02