Prajna Guha | Profiles RNS

Prajna Guha, PhD

Assistant Professor

Boston University Chobanian & Avedisian School of Medicine

Surgery

PhD, St John's University
MS, Northeastern University
BS, Jadavpur University

Websites

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	ResearchGate

Publications
Contact Info

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Ghosh CC, Cournoyer L, Liu Y, Ballarin A, Layman IB, LaPorte J, Morrissey M, Fraser K, Perati S, Cox BF, Yakirevich E, Treaba DO, Murtha TD, Guha P, Katz SC, Davar D. Subcutaneous checkpoint inhibition is equivalent to systemic delivery when combined with nelitolimod delivered via pressure-enabled drug delivery for depletion of intrahepatic myeloid-derived suppressor cells and control of liver metastases. J Immunother Cancer. 2024 Jul 22; 12(7).View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 39038918; PMCID: PMC11268044; DOI: 10.1136/jitc-2024-008837;

Sullivan KM, Jiang X, Guha P, Lausted C, Carter JA, Hsu C, Labadie KP, Kohli K, Kenerson HL, Daniel SK, Yan X, Meng C, Abbasi A, Chan M, Seo YD, Park JO, Crispe IN, Yeung RS, Kim TS, Gujral TS, Tian Q, Katz SC, Pillarisetty VG. Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases. Gut. 2023 Feb; 72(2):325-337.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 35705369; PMCID: PMC9872249; DOI: 10.1136/gutjnl-2021-325808;

Ghosh CC, Heatherton KR, Connell KPO, Alexander IS, Greer DA, LaPorte J, Guha P, Cox BF, Katz SC. Regional infusion of a class C TLR9 agonist enhances liver tumor microenvironment reprogramming and MDSC reduction to improve responsiveness to systemic checkpoint inhibition. Cancer Gene Ther. 2022 Dec; 29(12):1854-1865.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 35697801; PMCID: PMC9750861; DOI: 10.1038/s41417-022-00484-z;

Guha P, Heatherton KR, O'Connell KP, Alexander IS, Katz SC. Assessing the Future of Solid Tumor Immunotherapy. Biomedicines. 2022 Mar 11; 10(3).View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 35327456; PMCID: PMC8945484; DOI: 10.3390/biomedicines10030655;

Chai LF, Hardaway JC, Heatherton KR, O'Connell KP, LaPorte JP, Guha P, Lopes MC, Rabinowitz BA, Jaroch D, Cox BF, Knight R, Katz SC. Antigen Receptor T Cells (CAR-T) Effectively Control Tumor Growth in a Colorectal Liver Metastasis Model. J Surg Res. 2022 04; 272:37-50.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 34929499

Guha P, Katz SC. Strategies for manufacturing cell therapy products aligned with patient needs. Methods Cell Biol. 2022; 167:203-226.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 35152997

DaSilva NA, Barlock BJ, Guha P, Ghosh CC, Trebino CE, Camberg JL, Katz SC, Rowley DC. Proteomic signatures of myeloid derived suppressor cells from liver and lung metastases reveal functional divergence and potential therapeutic targets. Cell Death Discov. 2021 Sep 04; 7(1):232.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 34482371; PMCID: PMC8418613; DOI: 10.1038/s41420-021-00621-x;

Chai LF, Hardaway JC, Heatherton KR, O'Connell KP, Lopes MC, Rabinowitz BA, Ghosh CC, Guha P, Jaroch D, Cox BF, Katz SC. Regional Delivery of Anti-PD-1 Agent for Colorectal Liver Metastases Improves Therapeutic Index and Anti-Tumor Activity. Vaccines (Basel). 2021 Jul 21; 9(8).View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 34451932; PMCID: PMC8402391; DOI: 10.3390/vaccines9080807;

Guha P, Gardell J, Rabinowitz B, Lopes M, DaSilva NA, Rowley D, Katz SC. Monocytic and granulocytic myeloid-derived suppressor cell plasticity and differentiation are organ-specific. Oncogene. 2021 01; 40(3):693-704.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 33230244

Katz SC, Moody AE, Guha P, Hardaway JC, Prince E, LaPorte J, Stancu M, Slansky JE, Jordan KR, Schulick RD, Knight R, Saied A, Armenio V, Junghans RP. HITM-SURE: Hepatic immunotherapy for metastases phase Ib anti-CEA CAR-T study utilizing pressure enabled drug delivery. J Immunother Cancer. 2020 08; 8(2).View Related Profiles.

Stancu, Mirela
Guha, Prajna
Katz, Steven
Armenio, Vincent

PMID: 32843493; PMCID: PMC7449487; DOI: 10.1136/jitc-2020-001097;

Showing 10 of 17 results. Show More

Katz SC, Hardaway J, Prince E, Guha P, Cunetta M, Moody A, Wang LJ, Armenio V, Espat NJ, Junghans RP. HITM-SIR: phase Ib trial of intraarterial chimeric antigen receptor T-cell therapy and selective internal radiation therapy for CEA+ liver metastases. Cancer Gene Ther. 2020 05; 27(5):341-355.View Related Profiles.

Espat, Nocif
Guha, Prajna
Katz, Steven
Armenio, Vincent

PMID: 31155611

Guha P, Gardell J, Darpolor J, Cunetta M, Lima M, Miller G, Espat NJ, Junghans RP, Katz SC. STAT3 inhibition induces Bax-dependent apoptosis in liver tumor myeloid-derived suppressor cells. Oncogene. 2019 01; 38(4):533-548.View Related Profiles.

Espat, Nocif
Guha, Prajna
Katz, Steven

PMID: 30158673

Guha P, Morgan JW, Mostoslavsky G, Rodrigues NP, Boyd AS. Lack of Immune Response to Differentiated Cells Derived from Syngeneic Induced Pluripotent Stem Cells. Cell Stem Cell. 2017 07 06; 21(1):144-148.View Related Profiles.

Mostoslavsky, Gustavo
Guha, Prajna

PMID: 28686864

Guha P, Cunetta M, Somasundar P, Espat NJ, Junghans RP, Katz SC. Frontline Science: Functionally impaired geriatric CAR-T cells rescued by increased a5ß1 integrin expression. J Leukoc Biol. 2017 08; 102(2):201-208.View Related Profiles.

Espat, Nocif
Somasundar, Ponnandai
Guha, Prajna
Katz, Steven

PMID: 28546503; PMCID: PMC6608072; DOI: 10.1189/jlb.5HI0716-322RR;

Ghosh CC, David S, Zhang R, Berghelli A, Milam K, Higgins SJ, Hunter J, Mukherjee A, Wei Y, Tran M, Suber F, Kobzik L, Kain KC, Lu S, Santel A, Yano K, Guha P, Dumont DJ, Christiani DC, Parikh SM. Gene control of tyrosine kinase TIE2 and vascular manifestations of infections. Proc Natl Acad Sci U S A. 2016 Mar 01; 113(9):2472-7. PMID: 26884170; PMCID: PMC4780619; DOI: 10.1073/pnas.1519467113;

Burga RA, Thorn M, Point GR, Guha P, Nguyen CT, Licata LA, DeMatteo RP, Ayala A, Joseph Espat N, Junghans RP, Katz SC. Liver myeloid-derived suppressor cells expand in response to liver metastases in mice and inhibit the anti-tumor efficacy of anti-CEA CAR-T. Cancer Immunol Immunother. 2015 Jul; 64(7):817-29.View Related Profiles.

Guha, Prajna
Katz, Steven

PMID: 25850344; PMCID: PMC4485571; DOI: 10.1007/s00262-015-1692-6;

Guha P, Morgan JW, Mostoslavsky G, Rodrigues NP, Boyd AS. Lack of immune response to differentiated cells derived from syngeneic induced pluripotent stem cells. Cell Stem Cell. 2013 Apr 4; 12(4):407-12.View Related Profiles.

Mostoslavsky, Gustavo
Guha, Prajna

PMID: 23352605; DOI: 10.1016/j.stem.2013.01.006;

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 17 publications over 10 distinct years, with a maximum of 4 publications in 2021

Bar chart showing 17 publications over 10 distinct years, with a maximum of 4 publications in 2021

Year	Publications
2013	1
2015	1
2016	1
2017	2
2018	1
2019	1
2020	2
2021	4
2022	3
2024	1

Contact for Mentoring:

72 E. Concord Street
Boston MA 02118
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617.358.7492

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