Keywords
Last Name

Cesar Sommer

TitlePostdoctoral Fellow
InstitutionBoston University School of Medicine
DepartmentGeneral Internal Medicine
Address650 Albany St Evans Biomed Research Ctr
Boston MA 02118
Phone(617) 638-6572
 Research Expertise & Professional Interests
Scientist with a background in stem cell biology. Expertise in the generation and genetic engineering of Chimeric Antigen Receptor (CAR) T cells for cancer immunotherapy.

 Publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Etchegaray JP, Chavez L, Huang Y, Ross KN, Choi J, Martinez-Pastor B, Walsh RM, Sommer CA, Lienhard M, Gladden A, Kugel S, Silberman DM, Ramaswamy S, Mostoslavsky G, Hochedlinger K, Goren A, Rao A, Mostoslavsky R. The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine. Nat Cell Biol. 2015 May; 17(5):545-57. PMID: 25915124.
    View in: PubMed
  2. Sommer CA, Mostoslavsky G. RNA-Seq analysis of enteroendocrine cells reveals a role for FABP5 in the control of GIP secretion. Mol Endocrinol. 2014 Nov; 28(11):1855-65. PMID: 25268051.
    View in: PubMed
  3. Fragola G, Germain PL, Laise P, Cuomo A, Blasimme A, Gross F, Signaroldi E, Bucci G, Sommer C, Pruneri G, Mazzarol G, Bonaldi T, Mostoslavsky G, Casola S, Testa G. Cell reprogramming requires silencing of a core subset of polycomb targets. PLoS Genet. 2013; 9(2):e1003292. PMID: 23468641.
    View in: PubMed
  4. Sommer CA, Mostoslavsky G. The evolving field of induced pluripotency: recent progress and future challenges. J Cell Physiol. 2013 Feb; 228(2):267-75. PMID: 22767332.
    View in: PubMed
  5. Sommer CA, Christodoulou C, Gianotti-Sommer A, Shen SS, Sailaja BS, Hezroni H, Spira A, Meshorer E, Kotton DN, Mostoslavsky G. Residual expression of reprogramming factors affects the transcriptional program and epigenetic signatures of induced pluripotent stem cells. PLoS One. 2012; 7(12):e51711. PMID: 23272148.
    View in: PubMed
  6. Christodoulou C, Longmire TA, Shen SS, Bourdon A, Sommer CA, Gadue P, Spira A, Gouon-Evans V, Murphy GJ, Mostoslavsky G, Kotton DN. Mouse ES and iPS cells can form similar definitive endoderm despite differences in imprinted genes. J Clin Invest. 2011 Jun; 121(6):2313-25. PMID: 21537085.
    View in: PubMed
  7. Ye JH, Xu YJ, Gao J, Yan SG, Zhao J, Tu Q, Zhang J, Duan XJ, Sommer CA, Mostoslavsky G, Kaplan DL, Wu YN, Zhang CP, Wang L, Chen J. Critical-size calvarial bone defects healing in a mouse model with silk scaffolds and SATB2-modified iPSCs. Biomaterials. 2011 Aug; 32(22):5065-76. PMID: 21492931.
    View in: PubMed
  8. Koh KP, Yabuuchi A, Rao S, Huang Y, Cunniff K, Nardone J, Laiho A, Tahiliani M, Sommer CA, Mostoslavsky G, Lahesmaa R, Orkin SH, Rodig SJ, Daley GQ, Rao A. Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell. 2011 Feb 4; 8(2):200-13. PMID: 21295276.
    View in: PubMed
  9. Duan X, Tu Q, Zhang J, Ye J, Sommer C, Mostoslavsky G, Kaplan D, Yang P, Chen J. Application of induced pluripotent stem (iPS) cells in periodontal tissue regeneration. J Cell Physiol. 2011 Jan; 226(1):150-7. PMID: 20658533.
    View in: PubMed
  10. Somers A, Jean JC, Sommer CA, Omari A, Ford CC, Mills JA, Ying L, Sommer AG, Jean JM, Smith BW, Lafyatis R, Demierre MF, Weiss DJ, French DL, Gadue P, Murphy GJ, Mostoslavsky G, Kotton DN. Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette. Stem Cells. 2010 Oct; 28(10):1728-40. PMID: 20715179.
    View in: PubMed
  11. Sommer CA, Mostoslavsky G. Experimental approaches for the generation of induced pluripotent stem cells. Stem Cell Res Ther. 2010; 1(3):26. PMID: 20699015.
    View in: PubMed
  12. Staerk J, Dawlaty MM, Gao Q, Maetzel D, Hanna J, Sommer CA, Mostoslavsky G, Jaenisch R. Reprogramming of human peripheral blood cells to induced pluripotent stem cells. Cell Stem Cell. 2010 Jul 2; 7(1):20-4. PMID: 20621045.
    View in: PubMed
  13. Sommer CA, Sommer AG, Longmire TA, Christodoulou C, Thomas DD, Gostissa M, Alt FW, Murphy GJ, Kotton DN, Mostoslavsky G. Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells. 2010 Jan; 28(1):64-74. PMID: 19904830.
    View in: PubMed
  14. Sommer CA, Stadtfeld M, Murphy GJ, Hochedlinger K, Kotton DN, Mostoslavsky G. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells. 2009 Mar; 27(3):543-9. PMID: 19096035.
    View in: PubMed
  15. Gianotti A, Sommer CA, Carmona AK, Henrique-Silva F. Inhibitory effect of the sugarcane cystatin CaneCPI-4 on cathepsins B and L and human breast cancer cell invasion. Biol Chem. 2008 Apr; 389(4):447-53. PMID: 18208350.
    View in: PubMed
  16. Sommer CA, Pavarino-Bertelli EC, Goloni-Bertollo EM, Henrique-Silva F. Identification of dysregulated genes in lymphocytes from children with Down syndrome. Genome. 2008 Jan; 51(1):19-29. PMID: 18356936.
    View in: PubMed
  17. Reyes LF, Sommer CA, Beltramini LM, Henrique-Silva F. Expression, purification, and structural analysis of (HIS)UBE2G2 (human ubiquitin-conjugating enzyme). Protein Expr Purif. 2006 Feb; 45(2):324-8. PMID: 16214370.
    View in: PubMed
  18. Malagó W, Sommer CA, Del Cistia Andrade C, Soares-Costa A, Abrao Possik P, Cassago A, Santejo Silveira HC, Henrique-Silva F. Gene expression profile of human Down syndrome leukocytes. Croat Med J. 2005 Aug; 46(4):647-56. PMID: 16100769.
    View in: PubMed
  19. Possik PA, Sommer CA, Issa Hori J, Machado-Santelli GM, Jamur MC, Henrique-Silva F. DSCR2, a Down syndrome critical region protein, is localized to the endoplasmic reticulum of mammalian cells. Eur J Histochem. 2004 Jul-Sep; 48(3):267-72. PMID: 15590417.
    View in: PubMed
  20. Silveira HC, Sommer CA, Soares-Costa A, Henrique-Silva F. A calcineurin inhibitory protein overexpressed in Down's syndrome interacts with the product of a ubiquitously expressed transcript. Braz J Med Biol Res. 2004 Jun; 37(6):785-9. PMID: 15264020.
    View in: PubMed
  21. Sommer CA, Silva FH, Novo MT. Teaching molecular biology to undergraduate biology students: An illustration of protein expression and purification*. Biochem Mol Biol Educ. 2004 Jan; 32(1):7-10. PMID: 21706680.
    View in: PubMed
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