Defining immune-evasive mechanical signaling in head and neck cancer06/06/2024 - 03/31/2029 (PI)
NIH/National Institute of Dental & Craniofacial Research5R01DE033519-02
Targeting Transcriptional Networks Directing Immune Evasion in Progressive Bronchial Premalignant Lesions07/01/2024 - 06/30/2027 (PI)
Department of Defense/Army Medical Research Acquisition Activity
Defining age-associated alterations in oral squamous cell carcinoma04/01/2023 - 03/31/2027 (Key Person / Mentor)
PI:
Anthony SpinellaNIH/National Institute on Aging5F30AG077929-03
YAP/TAZ induce pulmonary capillary activation and drive alveolar stromal remodeling01/01/2025 - 12/31/2026 (PI)
American Heart Association
Defining epithelial polarity cues that direct cell fate02/15/2020 - 01/31/2026 (PI)
NIH/National Heart, Lung, and Blood Institute5R01HL124392-10
Defining the Beta-catenin/CBP axis in head and neck cancer12/07/2020 - 11/30/2025 (Multi-PI)
PI:
Xaralabos Varelas, PhDNIH/National Institute of Dental & Craniofacial Research5R01DE030350-05
Defining molecular signals that influence airway basal cell renewal and growth01/01/2020 - 06/30/2023 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute5F31HL149381-04
Intercepting aberrant YAP/TAZ activity for the treatment of lung cancer12/29/2017 - 06/30/2023 (PI)
Janssen Research & Development, LLC
Mechanobiology of Lung Fibrosis04/03/2019 - 03/31/2023 (Subcontract PI)
Mayo Clinic NIH NHLBI5R01HL092961-12
Understanding aberrant YAP signaling in squamous cell lung cancer07/01/2017 - 12/31/2022 (PI)
American Cancer Society, Inc.
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Mechanotransduction and YAP/TAZ Signaling in Pulmonary Arterial Hypertension01/01/2018 - 12/31/2021 (Subcontract PI)
The Brigham and Women's Hospital, Inc. NIH NHLBI5R01HL137366-04
Defining non-nuclear roles for Yap in the development of multi-ciliated cells04/01/2018 - 03/31/2021 (PI)
NIH/National Institute of Child Health & Human Development5R21HD094012-02
YAP/TAZ-NRG1 crosstalk in airway epithelial cell fate control03/01/2019 - 02/28/2021 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute5F31HL146163-02
Defining Epithelial Cell Polarity Cues That Direct Cell Fate08/15/2014 - 02/14/2020 (PI)
NIH/National Heart, Lung, and Blood Institute5R01HL124392-05
Understanding the etiology of airway carcinomas via global proteomic, phospho-proteomic and metabolomic analyses01/01/2019 - 12/31/2019 (PI)
Johnson & Johnson
Understanding the Molecular Mechanisms Controlling Multi-cilia Development10/15/2018 - 10/14/2019 (PI)
Charles H. Hood Foundation
Mechanobiology of Lung Fibrosis12/01/2014 - 11/30/2018 (Subcontract PI)
Mayo Clinic NIH NHLBI5R01HL092961-08
Understanding the Molecular Mechanisms Controlling Multi-cilia Development06/01/2017 - 07/31/2018 (PI)
March of Dimes Foundation
Defining Epithelial Cues Contributing to Sjogren's Syndrome07/01/2016 - 06/30/2018 (PI)
Sjogren's Foundation
Regulation of the Ciliated Cell Program in Airway Progenitors06/01/2016 - 05/31/2018 (Subcontract PI)
Trustees Of Columbia University In The City Of New York NIH NHLBI5R01HL119836-03
Defining aberrant epithelial cell polarity-regulated cues in breast cancer09/01/2014 - 08/31/2017 (PI)
Department of Defense/Army Medical Research Acquisition Activity
Specification and patterning of the developing airway by cell polarity regulated cues06/01/2015 - 05/31/2017 (PI)
March of Dimes Foundation
Defective Cell Polarity and Hippo Signalling in the Etiology of Sjogren's Syndrome04/01/2014 - 03/31/2016 (Co-Investigator)
PI:
Maria A. Kukuruzinska, PhDBiogen Idec
Institutional Research Grant01/01/2012 - 12/31/2015 (PI of Sub-Project / SP)
PI:
Avrum Spira, MDAmerican Cancer Society - MA Division
Roles of the Hippo pathway effectors Taz/Yap in mesenchymal stem cell fate specification12/01/2013 - 11/30/2015 (Subcontract PI)
Boston Nutrition Obesity Research Center NIH NIDDK5P30DK046200-22
Defining Polarity Cues that Control Tumor Initiation and Progression07/01/2012 - 06/30/2014 (PI)
Concern Foundation
Defining Cell Polarity Cues That Direct Hippo Signaling To Influence Ciliogenesis02/01/2012 - 01/31/2014 (PI)
March of Dimes
Defining Cell Polarity Cues That Direct Hippo Signaling To Influence Ciliogenesis02/01/2012 - 01/31/2014 (PI)
March of Dimes