Jingyi Zhao, PhD
Postdoctoral Associate
Boston University Chobanian & Avedisian School of Medicine
Biochemistry & Cell Biology




Research Interests:

1. Optical and chemical modulation of enzyme activity in living cells and living animals with high spatial-temporal resolution.
2. Optical and chemical modulation of endogenous signaling pathway with engineered effector protein to elucidate kinase function during cancer development.
3. Developing protein-based pro-drug for cancer therapy and immunotherapy.
4. Function and mechanism study of lysine post-translational modification (PTM) on different proteins

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Maziarz M, Federico A, Zhao J, Dujmusic L, Zhao Z, Monti S, Varelas X, Garcia-Marcos M. Naturally occurring hotspot cancer mutations in Ga13 promote oncogenic signaling. J Biol Chem. 2020 Dec 04; 295(49):16897-16904.View Related Profiles. PMID: 33453920
     
  2. Maziarz M, Federico A, Zhao J, Dujmusic L, Zhao Z, Monti S, Varelas X, Garcia-Marcos M. Naturally occurring hotspot cancer mutations in Ga13 promote oncogenic signaling. J Biol Chem. 2020 12 04; 295(49):16897-16904.View Related Profiles. PMID: 33109615; PMCID: PMC7864081; DOI: 10.1074/jbc.AC120.014698;
     
  3. Marivin A, Maziarz M, Zhao J, DiGiacomo V, Olmos Calvo I, Mann EA, Ear J, Blanco-Canosa JB, Ross EM, Ghosh P, Garcia-Marcos M. DAPLE protein inhibits nucleotide exchange on Gas and Gaq via the same motif that activates Gai. J Biol Chem. 2020 02 21; 295(8):2270-2284.View Related Profiles. PMID: 31949046; PMCID: PMC7039542; DOI: 10.1074/jbc.RA119.011648;
     
  4. Wang J, Liu Y, Liu Y, Zheng S, Wang X, Zhao J, Yang F, Zhang G, Wang C, Chen PR. Time-resolved protein activation by proximal decaging in living systems. Nature. 2019 05; 569(7757):509-513. PMID: 31068699; DOI: 10.1038/s41586-019-1188-1;
     
  5. Zhao J, Liu Y, Lin F, Wang W, Yang S, Ge Y, Chen PR. Bioorthogonal Engineering of Bacterial Effectors for Spatial-Temporal Modulation of Cell Signaling. ACS Cent Sci. 2019 Jan 23; 5(1):145-152. PMID: 30693333; PMCID: PMC6346392; DOI: 10.1021/acscentsci.8b00751;
     
  6. Xie X, Li XM, Qin F, Lin J, Zhang G, Zhao J, Bao X, Zhu R, Song H, Li XD, Chen PR. Genetically Encoded Photoaffinity Histone Marks. J Am Chem Soc. 2017 05 17; 139(19):6522-6525. PMID: 28459554; DOI: 10.1021/jacs.7b01431;
     
  7. Zhu R, Hao Z, Lou H, Song Y, Zhao J, Chen Y, Zhu J, Chen PR. Structural characterization of the DNA-binding mechanism underlying the copper(II)-sensing MarR transcriptional regulator. J Biol Inorg Chem. 2017 Jul; 22(5):685-693. PMID: 28124121; DOI: 10.1007/s00775-017-1442-7;
     
  8. Fan X, Ge Y, Lin F, Yang Y, Zhang G, Ngai WS, Lin Z, Zheng S, Wang J, Zhao J, Li J, Chen PR. Optimized Tetrazine Derivatives for Rapid Bioorthogonal Decaging in Living Cells. Angew Chem Int Ed Engl. 2016 11 02; 55(45):14046-14050. PMID: 27735133; DOI: 10.1002/anie.201608009;
     
  9. Song Y, Yang M, Wegner SV, Zhao J, Zhu R, Wu Y, He C, Chen PR. A Genetically Encoded FRET Sensor for Intracellular Heme. ACS Chem Biol. 2015 Jul 17; 10(7):1610-5. PMID: 25860383; DOI: 10.1021/cb5009734;
     
  10. Li J, Yu J, Zhao J, Wang J, Zheng S, Lin S, Chen L, Yang M, Jia S, Zhang X, Chen PR. Palladium-triggered deprotection chemistry for protein activation in living cells. Nat Chem. 2014 Apr; 6(4):352-61. PMID: 24651204; DOI: 10.1038/nchem.1887;
     
Showing 10 of 12 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 12 publications over 8 distinct years, with a maximum of 3 publications in 2020

YearPublications
20131
20142
20151
20161
20172
20181
20191
20203

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