Kathryn L Lunetta, PhD
Professor
Boston University School of Public Health
Dept of Biostatistics

PhD, University of Michigan at Ann Arbor
MS, University of Michigan at Ann Arbor



Kathryn L. Lunetta, Ph.D. joined the Department of Biostatistics in the fall of 2004 as an Associate Professor. Prior to her arrival, she held positions in the biotechnology industry, and was on the faculty in the Biostatistics department at the Harvard School of Public Health and Dana-Farber Cancer Institute. Dr. Lunetta’s research focuses on statistical problems and study design and analysis issues in human genetics, particularly in the mapping of complex genetic diseases. Dr. Lunetta collaborates as a statistical geneticist on several projects studying the genetic components of complex traits such as Alzheimer Disease, atrial fibrillation, and successful aging/longevity, and the genetic epidemiology of breast cancer.


IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL
04/01/2018 - 03/31/2023 (Co-PI)
PI: Emelia J. Benjamin, MD, ScM
General Hospital Corp d/b/a Massachusetts General Hospital NIH NHLBI
2R01HL092577-10

EPIDEMIOLOGY OF BREAST CANCER SUBTYPES IN AFRICAN-AMERICAN WOMEN: A CONSORTIUM
08/01/2012 - 07/31/2018 (SP Co-PI of Sub-Project / SP)
PI: Julie R. Palmer, ScD
Roswell Park Cancer Institute NIH NCI
3P01CA151135-05S1

CHARGE CONSORTIUM: GENE DISCOVERY FOR CVD AND AGING PHENOTYPES
04/01/2015 - 07/14/2018 (PI)
University of Washington NIH NHLBI
5R01HL105756-06

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL
09/30/2014 - 03/31/2018 (PI)
General Hospital Corp d/b/a Massachusetts General Hospital NIH NHLBI
3R01HL092577-06S1

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL
04/15/2013 - 03/31/2018 (PI)
Massachusetts General Hospital NIH NHLBI
5R01HL092577-09

NOVEL MULTI-OMICS APPROACH TO THE BIOLOGY OF HEALTH AGING: FRAMINGHAM STUDY
09/15/2015 - 02/28/2018 (Co-PI)
PI: Joanne M. Murabito, MD
NIH/National Institute on Aging
2R56AG029451-05A1

CHARGE (COHORTS FOR HEART AND AGING RESEARCH IN GENETIC EPIDEMIOLOGY) CONSORTIUM: GENE DISCOVERY FOR CVD AND AGING PHENOTYPES
02/15/2011 - 12/31/2014 (PI)
University of Washington NIH NHLBI
5R01HL105756-03




Yr Title Project-Sub Proj Pubs
2018 IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL 2R01HL092577-10 146
2017 Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval 5R01HL092577-09 146
2016 Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval 4R01HL092577-08 146
2015 Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval 5R01HL092577-07 146
2015 Novel multi-omics approach to the biology of healthy aging: Framingham Study 2R56AG029451-05A1 2
2015 Biostatistics and Data Management 5P01CA151135-05-5844 40
2014 Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval 5R01HL092577-06 146
2014 Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval 3R01HL092577-06S1 146
2014 Biostatistics and Data Management 5P01CA151135-04-5844 40
2013 Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval 2R01HL092577-05 146
Showing 10 of 13 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA. A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease. Alzheimers Dement. 2019 Jan 03.View Related Profiles. PMID: 30503768.
     
  2. Lin H, Lunetta KL, Zhao Q, Mandaviya PR, Rong J, Benjamin EJ, Joehanes R, Levy D, van Meurs JBJ, Larson MG, Murabito JM. Whole Blood Gene Expression Associated With Clinical Biological Age. J Gerontol A Biol Sci Med Sci. 2019 Jan 01; 74(1):81-88.View Related Profiles. PMID: 30010802.
     
  3. Choi SH, Weng LC, Roselli C, Lin H, Haggerty CM, Shoemaker MB, Barnard J, Arking DE, Chasman DI, Albert CM, Chaffin M, Tucker NR, Smith JD, Gupta N, Gabriel S, Margolin L, Shea MA, Shaffer CM, Yoneda ZT, Boerwinkle E, Smith NL, Silverman EK, Redline S, Vasan RS, Burchard EG, Gogarten SM, Laurie C, Blackwell TW, Abecasis G, Carey DJ, Fornwalt BK, Smelser DT, Baras A, Dewey FE, Jaquish CE, Papanicolaou GJ, Sotoodehnia N, Van Wagoner DR, Psaty BM, Kathiresan S, Darbar D, Alonso A, Heckbert SR, Chung MK, Roden DM, Benjamin EJ, Murray MF, Lunetta KL, Lubitz SA, Ellinor PT. Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. JAMA. 2018 12 11; 320(22):2354-2364.View Related Profiles. PMID: 30535219; DOI: 10.1001/jama.2018.18179;.
     
  4. Logue MW, Lancour D, Farrell J, Simkina I, Fallin MD, Lunetta KL, Farrer LA. Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants. Front Neurosci. 2018; 12:592.View Related Profiles. PMID: 30210277.
     
  5. Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtimäki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Vardarajan B, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2018 Aug 14.View Related Profiles. PMID: 30108311; DOI: 10.1038/s41380-018-0112-7;.
     
  6. Orkaby AR, Lunetta KL, Sun FJ, Driver JA, Benjamin EJ, Hamburg NM, Mitchell GF, Vasan RS, Murabito JM. Cross-Sectional Association of Frailty and Arterial Stiffness In Community-Dwelling Older Adults: The Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2018 Jun 18.View Related Profiles. PMID: 29917058.
     
  7. Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT. Multi-ethnic genome-wide association study for atrial fibrillation. Nat Genet. 2018 Sep; 50(9):1225-1233.View Related Profiles. PMID: 29892015; DOI: 10.1038/s41588-018-0133-9;.
     
  8. Yao S, Hong CC, Ruiz-Narváez EA, Evans SS, Zhu Q, Schaefer BA, Yan L, Coignet MV, Lunetta KL, Sucheston-Campbell LE, Lee K, Bandera EV, Troester MA, Rosenberg L, Palmer JR, Olshan AF, Ambrosone CB. Genetic ancestry and population differences in levels of inflammatory cytokines in women: Role for evolutionary selection and environmental factors. PLoS Genet. 2018 06; 14(6):e1007368.View Related Profiles. PMID: 29879116; DOI: 10.1371/journal.pgen.1007368;.
     
  9. Bensen JT, Graff M, Young KL, Sethupathy P, Parker J, Pecot CV, Currin K, Haddad SA, Ruiz-Narváez EA, Haiman CA, Hong CC, Sucheston-Campbell LE, Zhu Q, Liu S, Yao S, Bandera EV, Rosenberg L, Lunetta KL, Ambrosone CB, Palmer JR, Troester MA, Olshan AF. A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. Breast Cancer Res. 2018 Jun 05; 20(1):45.View Related Profiles. PMID: 29871690; DOI: 10.1186/s13058-018-0964-4;.
     
  10. Murabito JM, Zhao Q, Larson MG, Rong J, Lin H, Benjamin EJ, Levy D, Lunetta KL. Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2018 May 09; 73(6):757-762.View Related Profiles. PMID: 28977464.
     
Showing 10 of 226 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 226 publications over 27 distinct years, with a maximum of 27 publications in 2017

YearPublications
19911
19922
19941
19953
19963
19972
19982
19993
20005
20015
20021
20041
20054
20062
20079
20089
200911
201012
201116
201214
201317
201418
201517
201622
201727
201817
20192
In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Statistical genetics
Genetic Epidemiology
healthy aging
Breast Cancer
Atrial Fibrillation
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