Kathryn L Lunetta, PhD
Professor
Boston University School of Public Health
Dept of Biostatistics

PhD, University of Michigan at Ann Arbor
MS, University of Michigan at Ann Arbor



Kathryn L. Lunetta, Ph.D. joined the Department of Biostatistics in the fall of 2004 as an Associate Professor. Prior to her arrival, she held positions in the biotechnology industry, and was on the faculty in the Biostatistics department at the Harvard School of Public Health and Dana-Farber Cancer Institute. Dr. Lunetta’s research focuses on statistical problems and study design and analysis issues in human genetics, particularly in the mapping of complex genetic diseases. Dr. Lunetta collaborates as a statistical geneticist on several projects studying the genetic components of complex traits such as Alzheimer Disease, atrial fibrillation, and successful aging/longevity, and the genetic epidemiology of breast cancer.

Investigator
Framingham Heart Study


Member
Boston University
Genome Science Institute


Member
Boston University
Evans Center for Interdisciplinary Biomedical Research




Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval
04/01/2022 - 03/31/2027 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
2R01HL092577-14

BUSPH Interdisciplinary Training Program for Biostatisticians
07/01/2021 - 06/30/2026 (Multi-PI)
PI: Kathryn L Lunetta, PhD
NIH/National Institute of General Medical Sciences
5T32GM140972-02

Using Electrocardiogram Genetics to Inform Arrhythmia Risk
01/20/2022 - 12/31/2025 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
1R01HL157635-01A1

CHARGE consortium: omics discovery for CVD and aging phenotypes
08/01/2022 - 06/30/2025 (Subcontract PI)
University of Washington NIH NHLBI
2R01HL105756-11

Role of peripheral immune cells in cognitive aging: The Framingham Offspring Study
04/15/2020 - 03/31/2025 (Multi-PI)
PI: Kathryn L Lunetta, PhD
NIH/National Institute on Aging
5R01AG067457-03

Novel Statistical Methods for Development of Polygenic Scores in Multi-Ancestry Cohorts
05/01/2022 - 04/30/2024 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute
1F31HL163952-01

Winter 2018 CENTER strategically focused Atrial Fibrillation Research Network
07/01/2018 - 06/30/2023 (Multi-PI)
PI: Kathryn L Lunetta, PhD
American Heart Association


Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval
04/01/2018 - 03/31/2023 (Co-Investigator)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
5R01HL092577-13

CHARGE (Cohorts for Heart and Aging Research) Consortium: Gene discovery for CVD and aging phenotypes
07/15/2018 - 07/31/2022 (Subcontract PI)
University of Washington NIH NHLBI
5R01HL105756-10

Genetics and Epigenetics of Atrial Fibrillation
07/01/2018 - 06/30/2022 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital American Heart Assoc


Showing 10 of 17 results. Show All Results


Title


Yr Title Project-Sub Proj Pubs
2022 BUSPH Interdisciplinary Training Program for Biostatisticians 5T32GM140972-02
2022 Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study 5R01AG067457-03
2022 IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL 2R01HL092577-14
2021 BUSPH Interdisciplinary Training Program for Biostatisticians 1T32GM140972-01
2021 Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study 5R01AG067457-02
2021 IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL 5R01HL092577-13 241
2020 Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study 1R01AG067457-01
2020 IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL 5R01HL092577-12 241
2019 IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL 5R01HL092577-11 241
2018 IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL 2R01HL092577-10 241
Showing 10 of 22 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis       Copy PMIDs To Clipboard

  1. Gao G, Zhao F, Ahearn TU, Lunetta KL, Troester MA, Du Z, Ogundiran TO, Ojengbede O, Blot W, Nathanson KL, Domchek SM, Nemesure B, Hennis A, Ambs S, McClellan J, Nie M, Bertrand K, Zirpoli G, Yao S, Olshan AF, Bensen JT, Bandera EV, Nyante S, Conti DV, Press MF, Ingles SA, John EM, Bernstein L, Hu JJ, Deming-Halverson SL, Chanock SJ, Ziegler RG, Rodriguez-Gil JL, Sucheston-Campbell LE, Sandler DP, Taylor JA, Kitahara CM, O'Brien KM, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Wang Q, Figueroa J, Biritwum R, Adjei E, Wiafe S, Ambrosone CB, Zheng W, Olopade OI, García-Closas M, Palmer JR, Haiman CA, Huo D. Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach. Hum Mol Genet. 2022 Sep 10; 31(18):3133-3143.View Related Profiles. PMID: 35554533; PMCID: PMC9476624; DOI: 10.1093/hmg/ddac102;
     
  2. Lazarte J, Jurgens SJ, Choi SH, Khurshid S, Morrill VN, Weng LC, Nauffal V, Pirruccello JP, Halford JL, Hegele RA, Ellinor PT, Lunetta KL, Lubitz SA. LMNA Variants and Risk of Adult-Onset Cardiac Disease. J Am Coll Cardiol. 2022 Jul 05; 80(1):50-59.View Related Profiles. PMID: 35772917
     
  3. Chung J, Das A, Sun X, Sobreira DR, Leung YY, Igartua C, Mozaffari S, Chou YF, Thiagalingam S, Mez J, Zhang X, Jun GR, Stein TD, Kunkle BW, Martin ER, Pericak-Vance MA, Mayeux R, Haines JL, Schellenberg GD, Nobrega MA, Lunetta KL, Pinto JM, Wang LS, Ober C, Farrer LA. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimers Dement. 2022 Jun 30.View Related Profiles. PMID: 35770850
     
  4. Siland JE, Geelhoed B, Roselli C, Wang B, Lin HJ, Weiss S, Trompet S, van den Berg ME, Soliman EZ, Chen LY, Ford I, Jukema JW, Macfarlane PW, Kornej J, Lin H, Lunetta KL, Kavousi M, Kors JA, Ikram MA, Guo X, Yao J, Dörr M, Felix SB, Völker U, Sotoodehnia N, Arking DE, Stricker BH, Heckbert SR, Lubitz SA, Benjamin EJ, Alonso A, Ellinor PT, van der Harst P, Rienstra M. Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium. PLoS One. 2022; 17(5):e0268768.View Related Profiles. PMID: 35594314; PMCID: PMC9122202; DOI: 10.1371/journal.pone.0268768;
     
  5. You Y, Hersh SW, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Aging Cell. 2022 Jun; 21(6):e13617.View Related Profiles. PMID: 35567427; PMCID: PMC9197405; DOI: 10.1111/acel.13617;
     
  6. Nauffal V, Morrill VN, Jurgens SJ, Choi SH, Hall AW, Weng LC, Halford JL, Austin-Tse C, Haggerty CM, Harris SL, Wong EK, Alonso A, Arking DE, Benjamin EJ, Boerwinkle E, Min YI, Correa A, Fornwalt BK, Heckbert SR, Kooperberg C, Lin HJ, J F Loos R, Rice KM, Gupta N, Blackwell TW, Mitchell BD, Morrison AC, Psaty BM, Post WS, Redline S, Rehm HL, Rich SS, Rotter JI, Soliman EZ, Sotoodehnia N, Lunetta KL, Ellinor PT, Lubitz SA. Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation. 2022 May 17; 145(20):1524-1533.View Related Profiles. PMID: 35389749; PMCID: PMC9117504; DOI: 10.1161/CIRCULATIONAHA.121.057261;
     
  7. Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, et al. NewView Related Profiles. PMID: 35379992; PMCID: PMC9005347; DOI: 10.1038/s41588-022-01024-z;
     
  8. Zhang X, Tong T, Chang A, Ang TFA, Tao Q, Auerbach S, Devine S, Qiu WQ, Mez J, Massaro J, Lunetta KL, Au R, Farrer LA. Midlife lipid and glucose levels are associated with Alzheimer's disease. Alzheimers Dement. 2022 Mar 23.View Related Profiles. PMID: 35319157
     
  9. Jurgens SJ, Choi SH, Morrill VN, Chaffin M, Pirruccello JP, Halford JL, Weng LC, Nauffal V, Roselli C, Hall AW, Oetjens MT, Lagerman B, vanMaanen DP, Aragam KG, Lunetta KL, Haggerty CM, Lubitz SA, Ellinor PT. Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank. Nat Genet. 2022 Mar; 54(3):240-250.View Related Profiles. PMID: 35177841; PMCID: PMC8930703; DOI: 10.1038/s41588-021-01011-w;
     
  10. Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W, Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ?2 for Alzheimer's disease. Alzheimers Dement. 2022 Nov; 18(11):2042-2054.View Related Profiles. PMID: 35142023; PMCID: PMC9360190; DOI: 10.1002/alz.12607;
     
Showing 10 of 281 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 281 publications over 30 distinct years, with a maximum of 27 publications in 2017

YearPublications
19911
19922
19941
19953
19963
19972
19982
19993
20005
20015
20021
20041
20054
20062
20079
20089
200911
201012
201116
201214
201317
201418
201517
201622
201727
201816
201919
20209
202119
202211

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Statistical genetics
Genetic Epidemiology
healthy aging
Breast Cancer
Atrial Fibrillation
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801 Massachusetts Ave Crosstown Center
Boston MA 02118
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