Kathryn Lunetta | Profiles RNS

Kathryn L Lunetta, PhD

Professor

Boston University School of Public Health

Biostatistics

PhD, University of Michigan at Ann Arbor
MS, University of Michigan at Ann Arbor
BA, Grinnell College

Pronouns: she/her/hers

Websites

	School of Public Health Faculty
	LinkedIn
	Scinapse.io
	Loop Frontiers
	ResearchGate

ORCID : 0000-0002-9268-810X

Kathryn L. Lunetta, Ph.D. is a Professor of Biostatistics and a statistical geneticist with more than 20 years of experience in statistics and genetics research. She has extensive experience with the design and analysis of genome- wide association studies and sequencing studies and collaborate on several large, national and international genetic epidemiology studies at Boston University and with the Framingham Heart study. Her methodological research focuses on statistical problems and study design and analysis issues in human genetics, particularly in the mapping of complex genetic diseases. Her collaborative work spans several fields, including the genetics of atrial fibrillation and related phenotypes, the genetics of healthy aging and reproduction, and Alzheimer disease. She is a member of the CHARGE (Cohorts for Heart and Aging Research) consortium and participates on the Steering and Analysis committees, and also a TOPMed investigator and analysis committee member. She is senior/primary statistician on several Alzheimer Disease related projects and for the Framingham Heart Study Atrial Fibrillation working groups, where she advises on methodology and long-term goals and provide day- to-day supervision of analyses. She is multi-PI of a Framingham Immune cell and brain aging project that seeks to identify immune cell and inflammatory biomarkers related to cognitive aging.

Diversity, Equity, Inclusion and Accessibility

To improve DEIJ in admissions, I have worked with others to revise our admissions rubrics to be more holistic, with the goal of increasing the diversity of our student body.
In my teaching, I have worked to find new genetic data sets that are less European ancestry-centric, and revised language to reflect current/changing best practices. In my research, I have mentored one of my students to focus her research on methods to ameliorate the effects of lack of diverse representation in genetic studies on underrepresented populations through improved statistical methods, while at the same time advocating for the improved representation that is of critical importance.

Investigator
Framingham Heart Study

Member
Boston University
Genome Science Institute

Member
Boston University
Evans Center for Interdisciplinary Biomedical Research

BU Research
NIH RePORTER Research

Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval
04/01/2022 - 03/31/2027 (Multi-PI)
PI: Kathryn L Lunetta, PhD
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
2R01HL092577-14

BUSPH Interdisciplinary Training Program for Biostatisticians
07/01/2021 - 06/30/2026 (Multi-PI)
PI: Kathryn L Lunetta, PhD
NIH/National Institute of General Medical Sciences
5T32GM140972-03

Using Electrocardiogram Genetics to Inform Arrhythmia Risk
01/20/2022 - 12/31/2025 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
5R01HL157635-02

CHARGE consortium: omics discovery for CVD and aging phenotypes
08/01/2022 - 06/30/2025 (Subcontract PI)
University of Washington NIH NHLBI
2R01HL105756-11

Role of peripheral immune cells in cognitive aging: The Framingham Offspring Study
04/15/2020 - 03/31/2025 (Multi-PI)
PI: Kathryn L Lunetta, PhD
NIH/National Institute on Aging
5R01AG067457-04

Winter 2018 CENTER strategically focused Atrial Fibrillation Research Network
07/01/2018 - 06/30/2024 (Multi-PI)
PI: Kathryn L Lunetta, PhD
American Heart Association

Novel Statistical Methods for Development of Polygenic Scores in Multi-Ancestry Cohorts
05/01/2022 - 04/30/2024 (Key Person / Mentor)
NIH/National Heart, Lung, and Blood Institute
5F31HL163952-02

Identification of Common Genetic Variants for Atrial Fibrillation and PR Interval
04/01/2018 - 03/31/2023 (Co-Investigator)
PI: Emelia J. Benjamin, MD, ScM
The General Hospital Corporation d/b/a Massachusetts General Hospital NIH NHLBI
5R01HL092577-13

CHARGE (Cohorts for Heart and Aging Research) Consortium: Gene discovery for CVD and aging phenotypes
07/15/2018 - 07/31/2022 (Subcontract PI)
University of Washington NIH NHLBI
5R01HL105756-10

Genetics and Epigenetics of Atrial Fibrillation
07/01/2018 - 06/30/2022 (Subcontract PI)
The General Hospital Corporation d/b/a Massachusetts General Hospital American Heart Assoc

Showing 10 of 17 results. Show All Results

Title

Yr	Title	Project-Sub Proj	Pubs
2023	BUSPH Interdisciplinary Training Program for Biostatisticians	5T32GM140972-03
2023	Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study	5R01AG067457-04
2023	IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL	5R01HL092577-15
2022	BUSPH Interdisciplinary Training Program for Biostatisticians	5T32GM140972-02
2022	Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study	5R01AG067457-03
2022	IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL	2R01HL092577-14
2021	BUSPH Interdisciplinary Training Program for Biostatisticians	1T32GM140972-01
2021	Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study	5R01AG067457-02
2021	IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL	5R01HL092577-13	241
2020	Role of Peripheral Immune Cells in Cognitive Aging: The Framingham Offspring Study	1R01AG067457-01

Showing 10 of 25 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

iCite Analysis Copy PMIDs To Clipboard

Ochs-Balcom HM, Preus L, Du Z, Elston RC, Teerlink CC, Jia G, Guo X, Cai Q, Long J, Ping J, Li B, Stram DO, Shu XO, Sanderson M, Gao G, Ahearn T, Lunetta KL, Zirpoli G, Troester MA, Ruiz-Narváez EA, Haddad SA, Figueroa J, John EM, Bernstein L, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Mancuso N, Press MF, Deming SL, Rodriguez-Gil JL, Yao S, Ogundiran TO, Ojengbede O, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Sandler DP, Taylor JA, Wang Q, O'Brien KM, Weinberg CR, Kitahara CM, Blot W, Nathanson KL, Hennis A, Nemesure B, Ambs S, Sucheston-Campbell LE, Bensen JT, Chanock SJ, Olshan AF, Ambrosone CB, Olopade OI, The Ghana Breast Health Study Team, Conti DV, Palmer J, García-Closas M, Huo D, Zheng W, Haiman C. Novel breast cancer susceptibility loci under linkage peaks identified in African ancestry consortia. Hum Mol Genet. 2024 Apr 08; 33(8):687-697.View Related Profiles.

Zirpoli, Gary
Lunetta, Kathryn

PMID: 38263910

Panitch R, Sahelijo N, Hu J, Nho K, Bennett DA, Lunetta KL, Au R, Stein TD, Farrer LA, Jun GR. APOE genotype-specific methylation patterns are linked to Alzheimer disease pathology and estrogen response. Transl Psychiatry. 2024 Feb 29; 14(1):129.View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Au, Rhoda
Stein, Thor

PMID: 38424036; PMCID: PMC10904829; DOI: 10.1038/s41398-024-02834-x;

Zirpoli GR, Pfeiffer RM, Bertrand KA, Huo D, Lunetta KL, Palmer JR. Addition of polygenic risk score to a risk calculator for prediction of breast cancer in US Black women. Breast Cancer Res. 2024 Jan 02; 26(1):2.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn
Bertrand, Kimberly

PMID: 38167144; PMCID: PMC10763003; DOI: 10.1186/s13058-023-01748-8;

Ragab AAY, Doyle MF, Chen J, Fang Y, Lunetta KL, Murabito JM. Aging-Related Immune Cell Phenotypes and Mortality in the Framingham Heart Study. Res Sq. 2023 Dec 26.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Fang, Yuan

PMID: 38234796; PMCID: PMC10793514; DOI: 10.21203/rs.3.rs-3773986/v1;

Zheng Y, Lunetta KL, Liu C, Smith AK, Sherva R, Miller MW, Logue MW. A novel principal component based method for identifying differentially methylated regions in Illumina Infinium MethylationEPIC BeadChip data. Epigenetics. 2023 Dec; 18(1):2207959.View Related Profiles.

Lunetta, Kathryn
Logue, Mark
Miller, Mark
Sherva, Richard

PMID: 37196182; PMCID: PMC10193914; DOI: 10.1080/15592294.2023.2207959;

Tao Q, Zhang C, Mercier G, Lunetta K, Ang TFA, Akhter-Khan S, Zhang Z, Taylor A, Killiany RJ, Alosco M, Mez J, Au R, Zhang X, Farrer LA, Qiu WWQ. Identification of an APOE e4-specific blood-based molecular pathway for Alzheimer's disease risk. Alzheimers Dement (Amst). 2023; 15(4):e12490.View Related Profiles.

Taylor, Andrew
Mercier, Gustavo
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Alosco, Michael
Tao, Qiushan
Au, Rhoda
Ang, Ting Fang Alvin

PMID: 37854772; PMCID: PMC10579631; DOI: 10.1002/dad2.12490;

Huang J, Wang Y, Stein TD, Ang TFA, Zhu Y, Tao Q, Lunetta KL, Mez J, Au R, Farrer LA, Qiu WQ, Zhang X. The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation of UNC5C and NAV3 loci. Res Sq. 2023 Sep 28.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Tao, Qiushan
Au, Rhoda
Stein, Thor
Ang, Ting Fang Alvin

PMID: 37841863; PMCID: PMC10571626; DOI: 10.21203/rs.3.rs-3376348/v1;

Chen J, Doyle MF, Fang Y, Mez J, Crane PK, Scollard P, Satizabal CL, Alosco ML, Qiu WQ, Murabito JM, Lunetta KL. Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort. Aging Cell. 2023 Oct; 22(10):e13955.View Related Profiles.

Satizabal, Claudia
Mez, Jesse
Murabito, Joanne
Lunetta, Kathryn
Alosco, Michael
Qiu, Wendy
Fang, Yuan

PMID: 37584418; PMCID: PMC10577533; DOI: 10.1111/acel.13955;

Fang Y, Doyle MF, Chen J, Mez J, Satizabal CL, Alosco ML, Qiu WQ, Lunetta KL, Murabito JM. Correction for: Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants. Aging (Albany NY). 2023 Aug 14; 15(15):7855-7856.View Related Profiles.

Satizabal, Claudia
Mez, Jesse
Murabito, Joanne
Lunetta, Kathryn
Alosco, Michael
Fang, Yuan

PMID: 37580144; PMCID: PMC10457073; DOI: 10.18632/aging.204988;

Tejeda M, Farrell J, Zhu C, Wetzler L, Lunetta KL, Bush WS, Martin ER, Wang LS, Schellenberg GD, Pericak-Vance MA, Haines JL, Farrer LA, Sherva R. DNA from multiple viral species is associated with Alzheimer's disease risk. Alzheimers Dement. 2024 Jan; 20(1):253-265.View Related Profiles.

Lunetta, Kathryn
Wetzler, Lee
Farrer, Lindsay
Sherva, Richard

PMID: 37578203; PMCID: PMC10840621; DOI: 10.1002/alz.13414;

Showing 10 of 311 results. Show More

Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, Kuksa PP, Li D, Lucio da Fonseca E, Mez JB, Palmer EL, Pillai J, Sherva RM, Song YE, Zhang X, Iqbal T, Pathak O, Valladares O, Kuzma AB, Abner E, Adams PM, Aguirre A, Albert MS, Albin RL, Allen M, Alvarez L, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Ayres G, Baldwin CT, Barber RC, Barnes LL, Barral S, Beach TG, Becker JT, Beecham GW, Beekly D, Benitez BA, Bennett D, Bertelson J, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Brewer J, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Chasse S, Chesselet MF, Chin NA, Chui HC, Chung J, Craft S, Crane PK, Cribbs DH, Crocco EA, Cruchaga C, Cuccaro ML, Cullum M, Darby E, Davis B, De Jager PL, DeCarli C, DeToledo J, Dick M, Dickson DW, Dombroski BA, Doody RS, Duara R, Ertekin-Taner N, Evans DA, Faber KM, Fairchild TJ, Fallon KB, Fardo DW, Farlow MR, Fernandez-Hernandez V, Ferris S, Foroud TM, Frosch MP, Fulton-Howard B, Galasko DR, Gamboa A, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Goate AM, Grabowski TJ, Graff-Radford NR, Green RC, Growdon JH, Hakonarson H, Hall J, Hamilton RL, Harari O, Hardy J, Harrell LE, Head E, Henderson VW, Hernandez M, Hohman T, Honig LS, Huebinger RM, Huentelman MJ, Hulette CM, Hyman BT, Hynan LS, Ibanez L, Jarvik GP, Jayadev S, Jin LW, Johnson K, Johnson L, Kamboh MI, Karydas AM, Katz MJ, Kauwe JS, Kaye JA, Keene CD, Khaleeq A, Kim R, Knebl J, Kowall NW, Kramer JH, Kukull WA, LaFerla FM, Lah JJ, Larson EB, Lerner A, Leverenz JB, Levey AI, Lieberman AP, Lipton RB, Logue M, Lopez OL, Lunetta KL, Lyketsos CG, Mains D, Margaret FE, Marson DC, Martin ERR, Martiniuk F, Mash DC, Masliah E, Massman P, Masurkar A, McCormick WC, McCurry SM, McDavid AN, McDonough S, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Monuki ES, Morris JC, Mukherjee S, Myers AJ, Nguyen T, O'Bryant S, Olichney JM, Ory M, Palmer R, Parisi JE, Paulson HL, Pavlik V, Paydarfar D, Perez V, Peskind E, Petersen RC, Pierce A, Polk M, Poon WW, Potter H, Qu L, Quiceno M, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reisch JS, Ringman JM, Roberson ED, Rodriguear M, Rogaeva E, Rosen HJ, Rosenberg RN, Royall DR, Sager MA, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Slifer SH, Small S, Smith AG, Smith JP, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Stevens AB, Strittmatter SM, Sultzer D, Swerdlow RH, Tanzi RE, Tilson JL, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, van Eldik LJ, Vance JM, Vardarajan BN, Vassar R, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Whitehead PL, Wijsman EM, Wilhelmsen KC, Williams B, Williamson J, Wilms H, Wingo TS, Wisniewski T, Woltjer RL, Woon M, Wright CB, Wu CK, Younkin SG, Yu CE, Yu L, Zhu X, Kunkle BW, Bush WS, Wang LS, Farrer LA, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Jun GR, Reitz C, Naj AC. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies LRRC4C, LHX5-AS1 and nominates ancestry-specific loci PTPRK , GRB14 , and KIAA0825 as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. medRxiv. 2023 Jul 08.View Related Profiles.

McKee, Ann
Jun, Gyungah
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Kowall, Neil
Sherva, Richard
Stern, Robert

PMID: 37461624; PMCID: PMC10350126; DOI: 10.1101/2023.07.06.23292311;

Weng LC, Khurshid S, Gunn S, Trinquart L, Lunetta KL, Xu H, Benjamin EJ, Ellinor PT, Anderson CD, Lubitz SA. Clinical and Genetic Atrial Fibrillation Risk and Discrimination of Cardioembolic From Noncardioembolic Stroke. Stroke. 2023 Jul; 54(7):1777-1785.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Trinquart, Ludovic

PMID: 37363945; PMCID: PMC10313140; DOI: 10.1161/STROKEAHA.122.041533;

Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Durant A, Hohman TJ, Cuccaro ML, Saykin AJ, Kukull WA, Bennett DA, Wang LS, Mayeux RP, Haines JL, Pericak-Vance MA, Schellenberg GD, Crane PK, Au R, Lunetta KL, Mez JB, Farrer LA. A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores. Mol Neurodegener. 2023 Jun 22; 18(1):40.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Au, Rhoda
Sherva, Richard
Devine, Sherral
Ang, Ting Fang Alvin

PMID: 37349795; PMCID: PMC10286470; DOI: 10.1186/s13024-023-00633-4;

Kentistou KA, Kaisinger LR, Stankovic S, Vaudel M, de Oliveira EM, Messina A, Walters RG, Liu X, Busch AS, Helgason H, Thompson DJ, Santon F, Petricek KM, Zouaghi Y, Huang-Doran I, Gudbjartsson DF, Bratland E, Lin K, Gardner EJ, Zhao Y, Jia R, Terao C, Riggan M, Bolla MK, Yazdanpanah M, Yazdanpanah N, Bradfield JP, Broer L, Campbell A, Chasman DI, Cousminer DL, Franceschini N, Franke LH, Girotto G, He C, Järvelin MR, Joshi PK, Kamatani Y, Karlsson R, Luan J, Lunetta KL, Mägi R, Mangino M, Medland SE, Meisinger C, Noordam R, Nutile T, Concas MP, Polašek O, Porcu E, Ring SM, Sala C, Smith AV, Tanaka T, van der Most PJ, Vitart V, Wang CA, Willemsen G, Zygmunt M, Ahearn TU, Andrulis IL, Anton-Culver H, Antoniou AC, Auer PL, Barnes CL, Beckmann MW, Berrington A, Bogdanova NV, Bojesen SE, Brenner H, Buring JE, Canzian F, Chang-Claude J, Couch FJ, Cox A, Crisponi L, Czene K, Daly MB, Demerath EW, Dennis J, Devilee P, De Vivo I, Dörk T, Dunning AM, Dwek M, Eriksson JG, Fasching PA, Fernandez-Rhodes L, Ferreli L, Fletcher O, Gago-Dominguez M, García-Closas M, García-Sáenz JA, González-Neira A, Grallert H, Guénel P, Haiman CA, Hall P, Hamann U, Hakonarson H, Hart RJ, Hickey M, Hooning MJ, Hoppe R, Hopper JL, Hottenga JJ, Hu FB, Hübner H, Hunter DJ, Jernström H, John EM, Karasik D, Khusnutdinova EK, Kristensen VN, Lacey JV, Lambrechts D, Launer LJ, Lind PA, Lindblom A, Magnusson PK, Mannermaa A, McCarthy MI, Meitinger T, Menni C, Michailidou K, Millwood IY, Milne RL, Montgomery GW, Nevanlinna H, Nolte IM, Nyholt DR, Obi N, O'Brien KM, Offit K, Oldehinkel AJ, Ostrowski SR, Palotie A, Pedersen OB, Peters A, Pianigiani G, Plaseska-Karanfilska D, Pouta A, Pozarickij A, Radice P, Rennert G, Rosendaal FR, Ruggiero D, Saloustros E, Sandler DP, Schipf S, Schmidt CO, Schmidt MK, Small K, Spedicati B, Stampfer M, Stone J, Tamimi RM, Teras LR, Tikkanen E, Turman C, Vachon CM, Wang Q, Winqvist R, Wolk A, Zemel BS, Zheng W, van Dijk KW, Alizadeh BZ, Bandinelli S, Boerwinkle E, Boomsma DI, Ciullo M, Chenevix-Trench G, Cucca F, Esko T, Gieger C, Grant SF, Gudnason V, Hayward C, Kolcic I, Kraft P, Lawlor DA, Martin NG, Nøhr EA, Pedersen NL, Pennell CE, Ridker PM, Robino A, Snieder H, Sovio U, Spector TD, Stöckl D, Sudlow C, Timpson NJ, Toniolo D, Uitterlinden A, Ulivi S, Völzke H, Wareham NJ, Widen E, Wilson JF, Pharoah PD, Li L, Easton DF, Njølstad P, Sulem P, Murabito JM, Murray A, Manousaki D, Juul A, Erikstrup C, Stefansson K, Horikoshi M, Chen Z, Farooqi IS, Pitteloud N, Johansson S, Day FR, Perry JR, Ong KK. Understanding the genetic complexity of puberty timing across the allele frequency spectrum. medRxiv. 2023 Jun 20.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 37503126; PMCID: PMC10371120; DOI: 10.1101/2023.06.14.23291322;

Young KL, Olshan AF, Lunetta K, Graff M, Williams LA, Yao S, Zirpoli GR, Troester M, Palmer JR. Influence of alcohol consumption and alcohol metabolism variants on breast cancer risk among Black women: results from the AMBER consortium. Breast Cancer Res. 2023 Jun 12; 25(1):66.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 37308906; PMCID: PMC10259046; DOI: 10.1186/s13058-023-01660-1;

Li D, Farrell JJ, Mez J, Martin ER, Bush WS, Ruiz A, Boada M, de Rojas I, Mayeux R, Haines JL, Vance MAP, Wang LS, Schellenberg GD, Lunetta KL, Farrer LA. Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews. Alzheimers Dement. 2023 Dec; 19(12):5550-5562.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay

PMID: 37260021; PMCID: PMC10689571; DOI: 10.1002/alz.13117;

Ilozumba MN, Yaghjyan L, Datta S, Zhao J, Hong CC, Lunetta KL, Zirpoli G, Bandera EV, Palmer JR, Yao S, Ambrosone CB, Cheng TD. mTOR pathway candidate genes and energy intake interaction on breast cancer risk in Black women from the Women's Circle of Health Study. Eur J Nutr. 2023 Sep; 62(6):2593-2604.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 37209192; PMCID: PMC10695182; DOI: 10.1007/s00394-023-03176-y;

Fang Y, Doyle MF, Chen J, Mez J, Satizabal CL, Alosco ML, Qiu WQ, Lunetta KL, Murabito JM. Circulating immune cell phenotypes are associated with age, sex, CMV, and smoking status in the Framingham Heart Study offspring participants. Aging (Albany NY). 2023 Apr 27; 15(10):3939-3966.View Related Profiles.

Satizabal, Claudia
Mez, Jesse
Murabito, Joanne
Lunetta, Kathryn
Alosco, Michael
Fang, Yuan

PMID: 37116193; PMCID: PMC10258017; DOI: 10.18632/aging.204686;

Jurgens SJ, Pirruccello JP, Choi SH, Morrill VN, Chaffin M, Lubitz SA, Lunetta KL, Ellinor PT. Adjusting for common variant polygenic scores improves yield in rare variant association analyses. Nat Genet. 2023 Mar 23. PMID: 36959364

Lunetta, Kathryn
Choi, Seung Hoan

PMID: 36959364

Ilozumba MN, Yaghjyan L, Datta S, Zhao J, Gong Z, Hong CC, Lunetta KL, Zirpoli G, Bandera EV, Palmer JR, Yao S, Ambrosone CB, Cheng TD. mTOR pathway candidate genes and physical activity interaction on breast cancer risk in black women from the women's circle of health study. Breast Cancer Res Treat. 2023 May; 199(1):137-146.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 36882608; PMCID: PMC10695183; DOI: 10.1007/s10549-023-06902-6;

Ilozumba MN, Yaghjyan L, Datta S, Zhao J, Hong CC, Lunetta KL, Zirpoli G, Bandera EV, Palmer JR, Yao S, Ambrosone CB, Cheng TD. mTOR pathway candidate genes and obesity interaction on breast cancer risk in black women from the Women's Circle of Health Study. Cancer Causes Control. 2023 May; 34(5):431-447.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 36790512; PMCID: PMC10695180; DOI: 10.1007/s10552-022-01657-9;

Wang Y, Huang J, Ang TFA, Zhu Y, Tao Q, Mez J, Alosco M, Denis GV, Belkina A, Gurnani A, Ross M, Gong B, Han J, Lunetta KL, Stein TD, Au R, Farrer LA, Zhang X, Qiu WQ. Circulating Endothelial Progenitor Cells Reduce the Risk of Alzheimer's Disease. medRxiv. 2023 Jan 18.View Related Profiles.

Belkina, Anna
Gurnani, Ashita
Denis, Gerald
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Alosco, Michael
Tao, Qiushan
Au, Rhoda
Stein, Thor
Ang, Ting Fang Alvin
Qiu, Wendy

PMID: 36711847; PMCID: PMC9882408; DOI: 10.1101/2023.01.16.23284571;

Huang J, Tao Q, Ang TFA, Farrell J, Zhu C, Wang Y, Stein TD, Lunetta KL, Massaro J, Mez J, Au R, Farrer LA, Qiu WQ, Zhang X. The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease. Transl Psychiatry. 2022 Dec 22; 12(1):523.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Tao, Qiushan
Au, Rhoda
Stein, Thor
Ang, Ting Fang Alvin
Qiu, Wendy

PMID: 36550123; PMCID: PMC9780312; DOI: 10.1038/s41398-022-02281-6;

Huang J, Stein TD, Wang Y, Ang TFA, Tao Q, Lunetta KL, Massaro J, Akhter-Khan SC, Mez J, Au R, Farrer LA, Zhang X, Qiu WQ. Blood levels of MCP-1 modulate the genetic risks of Alzheimer's disease mediated by HLA-DRB1 and APOE for Alzheimer's disease. Alzheimers Dement. 2023 May; 19(5):1925-1937.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Tao, Qiushan
Au, Rhoda
Stein, Thor
Ang, Ting Fang Alvin
Qiu, Wendy

PMID: 36396603; PMCID: PMC10182187; DOI: 10.1002/alz.12851;

Halford JL, Morrill VN, Choi SH, Jurgens SJ, Melloni G, Marston NA, Weng LC, Nauffal V, Hall AW, Gunn S, Austin-Tse CA, Pirruccello JP, Khurshid S, Rehm HL, Benjamin EJ, Boerwinkle E, Brody JA, Correa A, Fornwalt BK, Gupta N, Haggerty CM, Harris S, Heckbert SR, Hong CC, Kooperberg C, Lin HJ, Loos RJF, Mitchell BD, Morrison AC, Post W, Psaty BM, Redline S, Rice KM, Rich SS, Rotter JI, Schnatz PF, Soliman EZ, Sotoodehnia N, Wong EK, Sabatine MS, Ruff CT, Lunetta KL, Ellinor PT, Lubitz SA. Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes. Nat Commun. 2022 Sep 30; 13(1):5767.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 36180445; PMCID: PMC9525665; DOI: 10.1038/s41467-022-33534-z;

Gao G, Zhao F, Ahearn TU, Lunetta KL, Troester MA, Du Z, Ogundiran TO, Ojengbede O, Blot W, Nathanson KL, Domchek SM, Nemesure B, Hennis A, Ambs S, McClellan J, Nie M, Bertrand K, Zirpoli G, Yao S, Olshan AF, Bensen JT, Bandera EV, Nyante S, Conti DV, Press MF, Ingles SA, John EM, Bernstein L, Hu JJ, Deming-Halverson SL, Chanock SJ, Ziegler RG, Rodriguez-Gil JL, Sucheston-Campbell LE, Sandler DP, Taylor JA, Kitahara CM, O'Brien KM, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Wang Q, Figueroa J, Biritwum R, Adjei E, Wiafe S, Ambrosone CB, Zheng W, Olopade OI, García-Closas M, Palmer JR, Haiman CA, Huo D. Polygenic risk scores for prediction of breast cancer risk in women of African ancestry: a cross-ancestry approach. Hum Mol Genet. 2022 Sep 10; 31(18):3133-3143.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn
Bertrand, Kimberly

PMID: 35554533; PMCID: PMC9476624; DOI: 10.1093/hmg/ddac102;

Fang Y, Doyle MF, Chen J, Alosco ML, Mez J, Satizabal CL, Qiu WQ, Murabito JM, Lunetta KL. Association between inflammatory biomarkers and cognitive aging. PLoS One. 2022; 17(9):e0274350.View Related Profiles.

Satizabal, Claudia
Mez, Jesse
Murabito, Joanne
Lunetta, Kathryn
Alosco, Michael

PMID: 36083988; PMCID: PMC9462682; DOI: 10.1371/journal.pone.0274350;

Tao Q, Akhter-Khan SC, Ang TFA, DeCarli C, Alosco ML, Mez J, Killiany R, Devine S, Rokach A, Itchapurapu IS, Zhang X, Lunetta KL, Steffens DC, Farrer LA, Greve DN, Au R, Qiu WQ. Different loneliness types, cognitive function, and brain structure in midlife: Findings from the Framingham Heart Study. EClinicalMedicine. 2022 Nov; 53:101643.View Related Profiles.

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Devine, Sherral
Ang, Ting Fang Alvin
Qiu, Wendy

PMID: 36105871; PMCID: PMC9465265; DOI: 10.1016/j.eclinm.2022.101643;

Zheng Y, Lunetta KL, Liu C, Katrinli S, Smith AK, Miller MW, Logue MW. An evaluation of the genome-wide false positive rates of common methods for identifying differentially methylated regions using illumina methylation arrays. Epigenetics. 2022 Dec; 17(13):2241-2258.View Related Profiles.

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Lunetta, Kathryn
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Miller, Mark

PMID: 36047742; PMCID: PMC9665129; DOI: 10.1080/15592294.2022.2115600;

Halford JL, Morrill VN, Choi SH, Jurgens SJ, Melloni G, Marston NA, Weng LC, Nauffal V, Hall AW, Gunn S, Austin-Tse CA, Pirruccello JP, Khurshid S, Rehm HL, Benjamin EJ, Boerwinkle E, Brody JA, Correa A, Fornwalt BK, Gupta N, Haggerty CM, Harris S, Heckbert SR, Hong CC, Kooperberg C, Lin HJ, Loos RJF, Mitchell BD, Morrison AC, Post W, Psaty BM, Redline S, Rice KM, Rich SS, Rotter JI, Schnatz PF, Soliman EZ, Sotoodehnia N, Wong EK, Sabatine MS, Ruff CT, Lunetta KL, Ellinor PT, Lubitz SA. Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes. Nat Commun. 2022 Aug 30; 13(1):5106.View Related Profiles.

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PMID: 36042188; PMCID: PMC9427940; DOI: 10.1038/s41467-022-32009-5;

Lazarte J, Jurgens SJ, Choi SH, Khurshid S, Morrill VN, Weng LC, Nauffal V, Pirruccello JP, Halford JL, Hegele RA, Ellinor PT, Lunetta KL, Lubitz SA. LMNA Variants and Risk of Adult-Onset Cardiac Disease. J Am Coll Cardiol. 2022 Jul 05; 80(1):50-59.View Related Profiles.

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PMID: 35772917

Chung J, Das A, Sun X, Sobreira DR, Leung YY, Igartua C, Mozaffari S, Chou YF, Thiagalingam S, Mez J, Zhang X, Jun GR, Stein TD, Kunkle BW, Martin ER, Pericak-Vance MA, Mayeux R, Haines JL, Schellenberg GD, Nobrega MA, Lunetta KL, Pinto JM, Wang LS, Ober C, Farrer LA. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimers Dement. 2022 Jun 30.View Related Profiles.

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Stein, Thor

PMID: 35770850; PMCID: PMC9800643; DOI: 10.1002/alz.12719;

Siland JE, Geelhoed B, Roselli C, Wang B, Lin HJ, Weiss S, Trompet S, van den Berg ME, Soliman EZ, Chen LY, Ford I, Jukema JW, Macfarlane PW, Kornej J, Lin H, Lunetta KL, Kavousi M, Kors JA, Ikram MA, Guo X, Yao J, Dörr M, Felix SB, Völker U, Sotoodehnia N, Arking DE, Stricker BH, Heckbert SR, Lubitz SA, Benjamin EJ, Alonso A, Ellinor PT, van der Harst P, Rienstra M. Resting heart rate and incident atrial fibrillation: A stratified Mendelian randomization in the AFGen consortium. PLoS One. 2022; 17(5):e0268768.View Related Profiles.

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Lunetta, Kathryn

PMID: 35594314; PMCID: PMC9122202; DOI: 10.1371/journal.pone.0268768;

You Y, Hersh SW, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Aging Cell. 2022 Jun; 21(6):e13617.View Related Profiles.

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Lunetta, Kathryn
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Ikezu, Tsuneya
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PMID: 35567427; PMCID: PMC9197405; DOI: 10.1111/acel.13617;

Nauffal V, Morrill VN, Jurgens SJ, Choi SH, Hall AW, Weng LC, Halford JL, Austin-Tse C, Haggerty CM, Harris SL, Wong EK, Alonso A, Arking DE, Benjamin EJ, Boerwinkle E, Min YI, Correa A, Fornwalt BK, Heckbert SR, Kooperberg C, Lin HJ, J F Loos R, Rice KM, Gupta N, Blackwell TW, Mitchell BD, Morrison AC, Psaty BM, Post WS, Redline S, Rehm HL, Rich SS, Rotter JI, Soliman EZ, Sotoodehnia N, Lunetta KL, Ellinor PT, Lubitz SA. Monogenic and Polygenic Contributions to QTc Prolongation in the Population. Circulation. 2022 May 17; 145(20):1524-1533.View Related Profiles.

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Lunetta, Kathryn
Choi, Seung Hoan

PMID: 35389749; PMCID: PMC9117504; DOI: 10.1161/CIRCULATIONAHA.121.057261;

Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, et al. NewView Related Profiles.

Beiser, Alexa
DeStefano, Anita
Satizabal, Claudia
Peloso, Gina
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Yang, Qiong
Seshadri, Sudha
Zhang, Xiaoling

PMID: 35379992; PMCID: PMC9005347; DOI: 10.1038/s41588-022-01024-z;

Zhang X, Tong T, Chang A, Ang TFA, Tao Q, Auerbach S, Devine S, Qiu WQ, Mez J, Massaro J, Lunetta KL, Au R, Farrer LA. Midlife lipid and glucose levels are associated with Alzheimer's disease. Alzheimers Dement. 2023 Jan; 19(1):181-193.View Related Profiles.

Mez, Jesse
Massaro, Joseph
Lunetta, Kathryn
Farrer, Lindsay
Tao, Qiushan
Au, Rhoda
Auerbach, Sanford
Devine, Sherral
Ang, Ting Fang Alvin
Zhang, Xiaoling

PMID: 35319157; PMCID: PMC10078665; DOI: 10.1002/alz.12641;

Jurgens SJ, Choi SH, Morrill VN, Chaffin M, Pirruccello JP, Halford JL, Weng LC, Nauffal V, Roselli C, Hall AW, Oetjens MT, Lagerman B, vanMaanen DP, Aragam KG, Lunetta KL, Haggerty CM, Lubitz SA, Ellinor PT. Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank. Nat Genet. 2022 Mar; 54(3):240-250.View Related Profiles.

Lunetta, Kathryn
Choi, Seung Hoan

PMID: 35177841; PMCID: PMC8930703; DOI: 10.1038/s41588-021-01011-w;

Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W, Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Au R, Lunetta KL, Ikezu T, Stein TD, Farrer LA. Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ?2 for Alzheimer's disease. Alzheimers Dement. 2022 Nov; 18(11):2042-2054.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
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Farrer, Lindsay
Au, Rhoda
Stein, Thor
Ikezu, Tsuneya
Xia, Weiming

PMID: 35142023; PMCID: PMC9360190; DOI: 10.1002/alz.12607;

Fang Y, Doyle MF, Alosco ML, Mez J, Satizabal CL, Qiu WQ, Lunetta KL, Murabito JM. Cross-Sectional Association Between Blood Cell Phenotypes, Cognitive Function, and Brain Imaging Measures in the Community-Based Framingham Heart Study. J Alzheimers Dis. 2022; 87(3):1291-1305.View Related Profiles.

Satizabal, Claudia
Mez, Jesse
Murabito, Joanne
Lunetta, Kathryn
Alosco, Michael
Fang, Yuan

PMID: 35431244; PMCID: PMC9969805; DOI: 10.3233/JAD-215533;

Longchamps RJ, Yang SY, Castellani CA, Shi W, Lane J, Grove ML, Bartz TM, Sarnowski C, Liu C, Burrows K, Guyatt AL, Gaunt TR, Kacprowski T, Yang J, De Jager PL, Yu L, Bergman A, Xia R, Fornage M, Feitosa MF, Wojczynski MK, Kraja AT, Province MA, Amin N, Rivadeneira F, Tiemeier H, Uitterlinden AG, Broer L, Van Meurs JBJ, Van Duijn CM, Raffield LM, Lange L, Rich SS, Lemaitre RN, Goodarzi MO, Sitlani CM, Mak ACY, Bennett DA, Rodriguez S, Murabito JM, Lunetta KL, Sotoodehnia N, Atzmon G, Ye K, Barzilai N, Brody JA, Psaty BM, Taylor KD, Rotter JI, Boerwinkle E, Pankratz N, Arking DE. Genome-wide analysis of mitochondrial DNA copy number reveals loci implicated in nucleotide metabolism, platelet activation, and megakaryocyte proliferation. Hum Genet. 2022 Jan; 141(1):127-146.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 34859289; PMCID: PMC8758627; DOI: 10.1007/s00439-021-02394-w;

Hersh SW, You Y, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Alzheimers Dement. 2021 Dec; 17 Suppl 2:e058592.View Related Profiles.

Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Ikezu, Tsuneya
You, Yang

PMID: 34971140; DOI: 10.1002/alz.058592;

Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, Skanes AC, Bartz TM, Perez MV, Taylor KD, Lubitz SA, Ellinor PT, Lunetta KL, Pankow JS, Paré G, Sotoodehnia N, Benjamin EJ, Horvath S, Marcus GM. Epigenetic Age and the Risk of Incident Atrial Fibrillation. Circulation. 2021 12 14; 144(24):1899-1911.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn

PMID: 34587750; PMCID: PMC8671333; DOI: 10.1161/CIRCULATIONAHA.121.056456;

Du Z, Gao G, Adedokun B, Ahearn T, Lunetta KL, Zirpoli G, Troester MA, Ruiz-Narváez EA, Haddad SA, PalChoudhury P, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Mancuso N, Press MF, Deming SL, Rodriguez-Gil JL, Yao S, Ogundiran TO, Ojengbe O, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Sandler DP, Taylor JA, Wang Q, Weinberg CR, Kitahara CM, Blot W, Nathanson KL, Hennis A, Nemesure B, Ambs S, Sucheston-Campbell LE, Bensen JT, Chanock SJ, Olshan AF, Ambrosone CB, Olopade OI, Yarney J, Awuah B, Wiafe-Addai B, Conti DV, Palmer JR, Garcia-Closas M, Huo D, Haiman CA. Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry. J Natl Cancer Inst. 2021 09 04; 113(9):1168-1176.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
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PMID: 33769540; PMCID: PMC8418423; DOI: 10.1093/jnci/djab050;

Panitch R, Hu J, Chung J, Zhu C, Meng G, Xia W, Bennett DA, Lunetta KL, Ikezu T, Au R, Stein TD, Farrer LA, Jun GR. Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE e2 protective effect in Alzheimer disease. Mol Psychiatry. 2021 10; 26(10):6054-6064.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Hu, Jun
Lunetta, Kathryn
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Stein, Thor
Ikezu, Tsuneya
Xia, Weiming

PMID: 34480088; PMCID: PMC8758485; DOI: 10.1038/s41380-021-01266-z;

Khurshid S, Mars N, Haggerty CM, Huang Q, Weng LC, Hartzel DN, Lunetta KL, Ashburner JM, Anderson CD, Benjamin EJ, Salomaa V, Ellinor PT, Fornwalt BK, Ripatti S, Trinquart L, Lubitz SA. Predictive Accuracy of a Clinical and Genetic Risk Model for Atrial Fibrillation. Circ Genom Precis Med. 2021 10; 14(5):e003355.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Trinquart, Ludovic

PMID: 34463125; PMCID: PMC8530935; DOI: 10.1161/CIRCGEN.121.003355;

Ruth KS, Day FR, Hussain J, Martínez-Marchal A, Aiken CE, Azad A, Thompson DJ, Knoblochova L, Abe H, Tarry-Adkins JL, Gonzalez JM, Fontanillas P, Claringbould A, Bakker OB, Sulem P, Walters RG, Terao C, Turon S, Horikoshi M, Lin K, Onland-Moret NC, Sankar A, Hertz EPT, Timshel PN, Shukla V, Borup R, Olsen KW, Aguilera P, Ferrer-Roda M, Huang Y, Stankovic S, Timmers PRHJ, Ahearn TU, Alizadeh BZ, Naderi E, Andrulis IL, Arnold AM, Aronson KJ, Augustinsson A, Bandinelli S, Barbieri CM, Beaumont RN, Becher H, Beckmann MW, Benonisdottir S, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Boomsma DI, Bowker N, Brody JA, Broer L, Buring JE, Campbell A, Campbell H, Castelao JE, Catamo E, Chanock SJ, Chenevix-Trench G, Ciullo M, Corre T, Couch FJ, Cox A, Crisponi L, Cross SS, Cucca F, Czene K, Smith GD, de Geus EJCN, de Mutsert R, De Vivo I, Demerath EW, Dennis J, Dunning AM, Dwek M, Eriksson M, Esko T, Fasching PA, Faul JD, Ferrucci L, Franceschini N, Frayling TM, Gago-Dominguez M, Mezzavilla M, García-Closas M, Gieger C, Giles GG, Grallert H, Gudbjartsson DF, Gudnason V, Guénel P, Haiman CA, Håkansson N, Hall P, Hayward C, He C, He W, Heiss G, Høffding MK, Hopper JL, Hottenga JJ, Hu F, Hunter D, Ikram MA, Jackson RD, Joaquim MDR, John EM, Joshi PK, Karasik D, Kardia SLR, Kartsonaki C, Karlsson R, Kitahara CM, Kolcic I, Kooperberg C, Kraft P, Kurian AW, Kutalik Z, La Bianca M, LaChance G, Langenberg C, Launer LJ, Laven JSE, Lawlor DA, Le Marchand L, Li J, Lindblom A, Lindstrom S, Lindstrom T, Linet M, Liu Y, Liu S, Luan J, Mägi R, Magnusson PKE, Mangino M, Mannermaa A, Marco B, Marten J, Martin NG, Mbarek H, McKnight B, Medland SE, Meisinger C, Meitinger T, Menni C, Metspalu A, Milani L, Milne RL, Montgomery GW, Mook-Kanamori DO, Mulas A, Mulligan AM, Murray A, Nalls MA, Newman A, Noordam R, Nutile T, Nyholt DR, Olshan AF, Olsson H, Painter JN, Patel AV, Pedersen NL, Perjakova N, Peters A, Peters U, Pharoah PDP, Polasek O, Porcu E, Psaty BM, Rahman I, Rennert G, Rennert HS, Ridker PM, Ring SM, Robino A, Rose LM, Rosendaal FR, Rossouw J, Rudan I, Rueedi R, Ruggiero D, Sala CF, Saloustros E, Sandler DP, Sanna S, Sawyer EJ, Sarnowski C, Schlessinger D, Schmidt MK, Schoemaker MJ, Schraut KE, Scott C, Shekari S, Shrikhande A, Smith AV, Smith BH, Smith JA, Sorice R, Southey MC, Spector TD, Spinelli JJ, Stampfer M, Stöckl D, van Meurs JBJ, Strauch K, Styrkarsdottir U, Swerdlow AJ, Tanaka T, Teras LR, Teumer A, Þorsteinsdottir U, Timpson NJ, Toniolo D, Traglia M, Troester MA, Truong T, Tyrrell J, Uitterlinden AG, Ulivi S, Vachon CM, Vitart V, Völker U, Vollenweider P, Völzke H, Wang Q, Wareham NJ, Weinberg CR, Weir DR, Wilcox AN, van Dijk KW, Willemsen G, Wilson JF, Wolffenbuttel BHR, Wolk A, Wood AR, Zhao W, Zygmunt M, Chen Z, Li L, Franke L, Burgess S, Deelen P, Pers TH, Grøndahl ML, Andersen CY, Pujol A, Lopez-Contreras AJ, Daniel JA, Stefansson K, Chang-Claude J, van der Schouw YT, Lunetta KL, Chasman DI, Easton DF, Visser JA, Ozanne SE, Namekawa SH, Solc P, Murabito JM, Ong KK, Hoffmann ER, Murray A, Roig I, Perry JRB. Genetic insights into biological mechanisms governing human ovarian ageing. Nature. 2021 08; 596(7872):393-397.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 34349265; PMCID: PMC7611832; DOI: 10.1038/s41586-021-03779-7;

Choi SH, Jurgens SJ, Haggerty CM, Hall AW, Halford JL, Morrill VN, Weng LC, Lagerman B, Mirshahi T, Pettinger M, Guo X, Lin HJ, Alonso A, Soliman EZ, Kornej J, Lin H, Moscati A, Nadkarni GN, Brody JA, Wiggins KL, Cade BE, Lee J, Austin-Tse C, Blackwell T, Chaffin MD, Lee CJ, Rehm HL, Roselli C, Redline S, Mitchell BD, Sotoodehnia N, Psaty BM, Heckbert SR, Loos RJF, Vasan RS, Benjamin EJ, Correa A, Boerwinkle E, Arking DE, Rotter JI, Rich SS, Whitsel EA, Perez M, Kooperberg C, Fornwalt BK, Lunetta KL, Ellinor PT, Lubitz SA. Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis. Circ Genom Precis Med. 2021 08; 14(4):e003300.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Choi, Seung Hoan

PMID: 34319147; PMCID: PMC8373440; DOI: 10.1161/CIRCGEN.120.003300;

Adedokun B, Du Z, Gao G, Ahearn TU, Lunetta KL, Zirpoli G, Figueroa J, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Press MF, Deming-Halverson SL, Rodriguez-Gil JL, Yao S, Ogundiran TO, Ojengbede O, Blot W, Troester MA, Nathanson KL, Hennis A, Nemesure B, Ambs S, Fiorica PN, Sucheston-Campbell LE, Bensen JT, Kushi LH, Torres-Mejia G, Hu D, Fejerman L, Bolla MK, Dennis J, Dunning AM, Easton DF, Michailidou K, Pharoah PDP, Wang Q, Sandler DP, Taylor JA, O'Brien KM, Kitahara CM, Falusi AG, Babalola C, Yarney J, Awuah B, Addai-Wiafe B, Chanock SJ, Olshan AF, Ambrosone CB, Conti DV, Ziv E, Olopade OI, Garcia-Closas M, Palmer JR, Haiman CA, Huo D. Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women. Nat Commun. 2021 07 07; 12(1):4198.View Related Profiles.

Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 34234117; PMCID: PMC8263739; DOI: 10.1038/s41467-021-24327-x;

Sarnowski C, Chen H, Biggs ML, Wassertheil-Smoller S, Bressler J, Irvin MR, Ryan KA, Karasik D, Arnett DK, Cupples LA, Fardo DW, Gogarten SM, Heavner BD, Jain D, Kang HM, Kooperberg C, Mainous AG, Mitchell BD, Morrison AC, O'Connell JR, Psaty BM, Rice K, Smith AV, Vasan RS, Windham BG, Kiel DP, Murabito JM, Lunetta KL. Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program. PLoS One. 2021; 16(7):e0253611.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Cupples, L

PMID: 34214102; PMCID: PMC8253404; DOI: 10.1371/journal.pone.0253611;

McCartney DL, Min JL, Richmond RC, Lu AT, Sobczyk MK, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo PL, Matias-Garcia PR, Mishra PP, Nygaard M, Palviainen T, Patki A, Raffield LM, Ratliff SM, Richardson TG, Robinson O, Soerensen M, Sun D, Tsai PC, van der Zee MD, Walker RM, Wang X, Wang Y, Xia R, Xu Z, Yao J, Zhao W, Correa A, Boerwinkle E, Dugué PA, Durda P, Elliott HR, Gieger C, de Geus EJC, Harris SE, Hemani G, Imboden M, Kähönen M, Kardia SLR, Kresovich JK, Li S, Lunetta KL, Mangino M, Mason D, McIntosh AM, Mengel-From J, Moore AZ, Murabito JM, Ollikainen M, Pankow JS, Pedersen NL, Peters A, Polidoro S, Porteous DJ, Raitakari O, Rich SS, Sandler DP, Sillanpää E, Smith AK, Southey MC, Strauch K, Tiwari H, Tanaka T, Tillin T, Uitterlinden AG, Van Den Berg DJ, van Dongen J, Wilson JG, Wright J, Yet I, Arnett D, Bandinelli S, Bell JT, Binder AM, Boomsma DI, Chen W, Christensen K, Conneely KN, Elliott P, Ferrucci L, Fornage M, Hägg S, Hayward C, Irvin M, Kaprio J, Lawlor DA, Lehtimäki T, Lohoff FW, Milani L, Milne RL, Probst-Hensch N, Reiner AP, Ritz B, Rotter JI, Smith JA, Taylor JA, van Meurs JBJ, Vineis P, Waldenberger M, Deary IJ, Relton CL, Horvath S, Marioni RE. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biol. 2021 06 29; 22(1):194.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 34187551; PMCID: PMC8243879; DOI: 10.1186/s13059-021-02398-9;

Zhang X, Farrell JJ, Tong T, Hu J, Zhu C, Wang LS, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LA. Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease. Alzheimers Dement. 2022 02; 18(2):294-306.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Zhang, Xiaoling

PMID: 34152079; PMCID: PMC8764625; DOI: 10.1002/alz.12396;

Sarnowski C, Cousminer DL, Franceschini N, Raffield LM, Jia G, Fernández-Rhodes L, Grant SFA, Hakonarson H, Lange LA, Long J, Sofer T, Tao R, Wallace RB, Wong Q, Zirpoli G, Boerwinkle E, Bradfield JP, Correa A, Kooperberg CL, North KE, Palmer JR, Zemel BS, Zheng W, Murabito JM, Lunetta KL. Large trans-ethnic meta-analysis identifies AKR1C4 as a novel gene associated with age at menarche. Hum Reprod. 2021 06 18; 36(7):1999-2010.View Related Profiles.

Zirpoli, Gary
Murabito, Joanne
Palmer, Julie
Lunetta, Kathryn

PMID: 34021356; PMCID: PMC8213450; DOI: 10.1093/humrep/deab086;

Patel D, Zhang X, Farrell JJ, Chung J, Stein TD, Lunetta KL, Farrer LA. Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue. Transl Psychiatry. 2021 04 27; 11(1):250.View Related Profiles.

Chung, Jaeyoon
Lunetta, Kathryn
Farrer, Lindsay
Stein, Thor
Zhang, Xiaoling

PMID: 33907181; PMCID: PMC8079392; DOI: 10.1038/s41398-021-01373-z;

Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. 2021 Apr 23; 12(1):2463.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Sebastiani, Paola
Perls, Thomas

PMID: 33893282; PMCID: PMC8065049; DOI: 10.1038/s41467-021-22613-2;

Patel D, Zhang X, Farrell JJ, Lunetta KL, Farrer LA. Set-Based Rare Variant Expression Quantitative Trait Loci in Blood and Brain from Alzheimer Disease Study Participants. Genes (Basel). 2021 03 15; 12(3).View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Zhang, Xiaoling

PMID: 33804025; PMCID: PMC7999141; DOI: 10.3390/genes12030419;

Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Aguet F, Albert C, Alonso A, Ardlie KG, Arking DE, Aslibekyan S, Auer PL, Barnard J, Barr RG, Barwick L, Becker LC, Beer RL, Benjamin EJ, Bielak LF, Blangero J, Boehnke M, Bowden DW, Brody JA, Burchard EG, Cade BE, Casella JF, Chalazan B, Chasman DI, Chen YI, Cho MH, Choi SH, Chung MK, Clish CB, Correa A, Curran JE, Custer B, Darbar D, Daya M, de Andrade M, DeMeo DL, Dutcher SK, Ellinor PT, Emery LS, Eng C, Fatkin D, Fingerlin T, Forer L, Fornage M, Franceschini N, Fuchsberger C, Fullerton SM, Germer S, Gladwin MT, Gottlieb DJ, Guo X, Hall ME, He J, Heard-Costa NL, Heckbert SR, Irvin MR, Johnsen JM, Johnson AD, Kaplan R, Kardia SLR, Kelly T, Kelly S, Kenny EE, Kiel DP, Klemmer R, Konkle BA, Kooperberg C, Köttgen A, Lange LA, Lasky-Su J, Levy D, Lin X, Lin KH, Liu C, Loos RJF, Garman L, Gerszten R, Lubitz SA, Lunetta KL, Mak ACY, Manichaikul A, Manning AK, Mathias RA, McManus DD, McGarvey ST, Meigs JB, Meyers DA, Mikulla JL, Minear MA, Mitchell BD, Mohanty S, Montasser ME, Montgomery C, Morrison AC, Murabito JM, Natale A, Natarajan P, Nelson SC, North KE, O'Connell JR, Palmer ND, Pankratz N, Peloso GM, Peyser PA, Pleiness J, Post WS, Psaty BM, Rao DC, Redline S, Reiner AP, Roden D, Rotter JI, Ruczinski I, Sarnowski C, Schoenherr S, Schwartz DA, Seo JS, Seshadri S, Sheehan VA, Sheu WH, Shoemaker MB, Smith NL, Smith JA, Sotoodehnia N, Stilp AM, Tang W, Taylor KD, Telen M, Thornton TA, Tracy RP, Van Den Berg DJ, Vasan RS, Viaud-Martinez KA, Vrieze S, Weeks DE, Weir BS, Weiss ST, Weng LC, Willer CJ, Zhang Y, Zhao X, Arnett DK, Ashley-Koch AE, Barnes KC, Boerwinkle E, Gabriel S, Gibbs R, Rice KM, Rich SS, Silverman EK, Qasba P, Gan W, Papanicolaou GJ, Nickerson DA, Browning SR, Zody MC, Zöllner S, Wilson JG, Cupples LA, Laurie CC, Jaquish CE, Hernandez RD, O'Connor TD, Abecasis GR. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 02; 590(7845):290-299.View Related Profiles.

Liu, Chunyu
Benjamin, Emelia
Peloso, Gina
Murabito, Joanne
Lunetta, Kathryn
Cupples, L
Heard-Costa, Nancy
Seshadri, Sudha

PMID: 33568819; PMCID: PMC7875770; DOI: 10.1038/s41586-021-03205-y;

Jones G, Trajanoska K, Santanasto AJ, Stringa N, Kuo CL, Atkins JL, Lewis JR, Duong T, Hong S, Biggs ML, Luan J, Sarnowski C, Lunetta KL, Tanaka T, Wojczynski MK, Cvejkus R, Nethander M, Ghasemi S, Yang J, Zillikens MC, Walter S, Sicinski K, Kague E, Ackert-Bicknell CL, Arking DE, Windham BG, Boerwinkle E, Grove ML, Graff M, Spira D, Demuth I, van der Velde N, de Groot LCPGM, Psaty BM, Odden MC, Fohner AE, Langenberg C, Wareham NJ, Bandinelli S, van Schoor NM, Huisman M, Tan Q, Zmuda J, Mellström D, Karlsson M, Bennett DA, Buchman AS, De Jager PL, Uitterlinden AG, Völker U, Kocher T, Teumer A, Rodriguéz-Mañas L, García FJ, Carnicero JA, Herd P, Bertram L, Ohlsson C, Murabito JM, Melzer D, Kuchel GA, Ferrucci L, Karasik D, Rivadeneira F, Kiel DP, Pilling LC. Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women. Nat Commun. 2021 01 28; 12(1):654.View Related Profiles.

Sarnowski, Chloe
Murabito, Joanne
Lunetta, Kathryn

PMID: 33510174; PMCID: PMC7844411; DOI: 10.1038/s41467-021-20918-w;

Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, Obisesan TO, Kamboh MI, Bennett DA, Hall KS, Goate AM, Foroud TM, Martin ER, Wang LS, Byrd GS, Farrer LA, Haines JL, Schellenberg GD, Mayeux R, Pericak-Vance MA, Reitz C, Graff-Radford NR, Martinez I, Ayodele T, Logue MW, Cantwell LB, Jean-Francois M, Kuzma AB, Adams LD, Vance JM, Cuccaro ML, Chung J, Mez J, Lunetta KL, Jun GR, Lopez OL, Hendrie HC, Reiman EM, Kowall NW, Leverenz JB, Small SA, Levey AI, Golde TE, Saykin AJ, Starks TD, Albert MS, Hyman BT, Petersen RC, Sano M, Wisniewski T, Vassar R, Kaye JA, Henderson VW, DeCarli C, LaFerla FM, Brewer JB, Miller BL, Swerdlow RH, Van Eldik LJ, Paulson HL, Trojanowski JQ, Chui HC, Rosenberg RN, Craft S, Grabowski TJ, Asthana S, Morris JC, Strittmatter SM, Kukull WA. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. JAMA Neurol. 2021 01 01; 78(1):102-113.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Kowall, Neil

PMID: 33074286; PMCID: PMC7573798; DOI: 10.1001/jamaneurol.2020.3536;

Nichols HB, Graff M, Bensen JT, Lunetta KL, O'Brien KM, Troester MA, Williams LA, Young K, Hong CC, Yao S, Haiman CA, Ruiz-Narváez EA, Ambrosone CB, Palmer JR, Olshan AF. Genetic variants in anti-Müllerian hormone-related genes and breast cancer risk: results from the AMBER consortium. Breast Cancer Res Treat. 2021 Jan; 185(2):469-478.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn

PMID: 32960377; PMCID: PMC7867570; DOI: 10.1007/s10549-020-05944-4;

Weng LC, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H, Teumer A, Li-Gao R, Yao J, Guo X, Brody JA, Müller-Nurasyid M, Schramm K, Verweij N, van den Berg ME, van Setten J, Isaacs A, Ramírez J, Warren HR, Padmanabhan S, Kors JA, de Boer RA, van der Meer P, Sinner MF, Waldenberger M, Psaty BM, Taylor KD, Völker U, Kanters JK, Li M, Alonso A, Perez MV, Vaartjes I, Bots ML, Huang PL, Heckbert SR, Lin HJ, Kornej J, Munroe PB, van Duijn CM, Asselbergs FW, Stricker BH, van der Harst P, Kääb S, Peters A, Sotoodehnia N, Rotter JI, Mook-Kanamori DO, Dörr M, Felix SB, Linneberg A, Hansen T, Arking DE, Kooperberg C, Benjamin EJ, Lunetta KL, Ellinor PT, Lubitz SA. Genetic Determinants of Electrocardiographic P-Wave Duration and Relation to Atrial Fibrillation. Circ Genom Precis Med. 2020 10; 13(5):387-395.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Choi, Seung Hoan

PMID: 32822252; PMCID: PMC7578098; DOI: 10.1161/CIRCGEN.119.002874;

Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Cantwell L, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtimäki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Valladares O, Vardarajan B, Wang LS, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA. Correction: Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2020 Aug; 25(8):1901-1903.View Related Profiles.

DeStefano, Anita
Sarnowski, Chloe
Chung, Jaeyoon
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Seshadri, Sudha

PMID: 31636380; PMCID: PMC7387240; DOI: 10.1038/s41380-019-0529-7;

Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD, Roselli C, Barnes MR, Mifsud B, Warren HR, Hayward C, Marten J, Cranley JJ, Concas MP, Gasparini P, Boutin T, Kolcic I, Polasek O, Rudan I, Araujo NM, Lima-Costa MF, Ribeiro ALP, Souza RP, Tarazona-Santos E, Giedraitis V, Ingelsson E, Mahajan A, Morris AP, Del Greco M F, Foco L, Gögele M, Hicks AA, Cook JP, Lind L, Lindgren CM, Sundström J, Nelson CP, Riaz MB, Samani NJ, Sinagra G, Ulivi S, Kähönen M, Mishra PP, Mononen N, Nikus K, Caulfield MJ, Dominiczak A, Padmanabhan S, Montasser ME, O'Connell JR, Ryan K, Shuldiner AR, Aeschbacher S, Conen D, Risch L, Thériault S, Hutri-Kähönen N, Lehtimäki T, Lyytikäinen LP, Raitakari OT, Barnes CLK, Campbell H, Joshi PK, Wilson JF, Isaacs A, Kors JA, van Duijn CM, Huang PL, Gudnason V, Harris TB, Launer LJ, Smith AV, Bottinger EP, Loos RJF, Nadkarni GN, Preuss MH, Correa A, Mei H, Wilson J, Meitinger T, Müller-Nurasyid M, Peters A, Waldenberger M, Mangino M, Spector TD, Rienstra M, van de Vegte YJ, van der Harst P, Verweij N, Kääb S, Schramm K, Sinner MF, Strauch K, Cutler MJ, Fatkin D, London B, Olesen M, Roden DM, Benjamin Shoemaker M, Gustav Smith J, Biggs ML, Bis JC, Brody JA, Psaty BM, Rice K, Sotoodehnia N, De Grandi A, Fuchsberger C, Pattaro C, Pramstaller PP, Ford I, Wouter Jukema J, Macfarlane PW, Trompet S, Dörr M, Felix SB, Völker U, Weiss S, Havulinna AS, Jula A, Sääksjärvi K, Salomaa V, Guo X, Heckbert SR, Lin HJ, Rotter JI, Taylor KD, Yao J, de Mutsert R, Maan AC, Mook-Kanamori DO, Noordam R, Cucca F, Ding J, Lakatta EG, Qian Y, Tarasov KV, Levy D, Lin H, Newton-Cheh CH, Lunetta KL, Murray AD, Porteous DJ, Smith BH, Stricker BH, Uitterlinden A, van den Berg ME, Haessler J, Jackson RD, Kooperberg C, Peters U, Reiner AP, Whitsel EA, Alonso A, Arking DE, Boerwinkle E, Ehret GB, Soliman EZ, Avery CL, Gogarten SM, Kerr KF, Laurie CC, Seyerle AA, Stilp A, Assa S, Abdullah Said M, Yldau van der Ende M, Lambiase PD, Orini M, Ramirez J, Van Duijvenboden S, Arnar DO, Gudbjartsson DF, Holm H, Sulem P, Thorleifsson G, Thorolfsdottir RB, Thorsteinsdottir U, Benjamin EJ, Tinker A, Stefansson K, Ellinor PT, Jamshidi Y, Lubitz SA, Munroe PB. Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nat Commun. 2020 05 21; 11(1):2542.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Choi, Seung Hoan

PMID: 32439900; PMCID: PMC7242331; DOI: 10.1038/s41467-020-15706-x;

Staerk L, Preis SR, Lin H, Casas JP, Lunetta K, Weng LC, Anderson CD, Ellinor PT, Lubitz SA, Benjamin EJ, Trinquart L. Novel Risk Modeling Approach of Atrial Fibrillation With Restricted Mean Survival Times: Application in the Framingham Heart Study Community-Based Cohort. Circ Cardiovasc Qual Outcomes. 2020 04; 13(4):e005918.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Trinquart, Ludovic
Preis, Sarah

PMID: 32228064; PMCID: PMC7176529; DOI: 10.1161/CIRCOUTCOMES.119.005918;

Cox JW, Sherva RM, Lunetta KL, Saitz R, Kon M, Kranzler HR, Gelernter J, Farrer LA. Identifying factors associated with opioid cessation in a biracial sample using machine learning. Explor Med. 2020; 1(1):27-41.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Saitz, Richard
Sherva, Richard

PMID: 33554217; PMCID: PMC7861053; DOI: 10.37349/emed.2020.00003;

Feitosa MF, Lunetta KL, Wang L, Wojczynski MK, Kammerer CM, Perls T, Schupf N, Christensen K, Murabito JM, Province MA. Gene discovery for high-density lipoprotein cholesterol level change over time in prospective family studies. Atherosclerosis. 2020 03; 297:102-110.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Perls, Thomas

PMID: 32109663; PMCID: PMC8098811; DOI: 10.1016/j.atherosclerosis.2020.02.005;

Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Keene CD, Kamboh MI, Kofler JK, Duque L, Gilbert JR, Gwirtsman HE, Buxbaum JD, Dickson DW, Frosch MP, Ghetti BF, Lunetta KL, Wang LS, Hyman BT, Kukull WA, Foroud T, Haines JL, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Farrer LA, Schellenberg GD, Beecham GW, Montine TJ, Jun GR. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nat Commun. 2020 02 03; 11(1):667.View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay

PMID: 32015339; PMCID: PMC6997393; DOI: 10.1038/s41467-019-14279-8;

Cox JW, Sherva RM, Lunetta KL, Johnson EC, Martin NG, Degenhardt L, Agrawal A, Nelson EC, Kranzler HR, Gelernter J, Farrer LA. Genome-Wide Association Study of Opioid Cessation. J Clin Med. 2020 Jan 09; 9(1).View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Sherva, Richard

PMID: 31936517; PMCID: PMC7019731; DOI: 10.3390/jcm9010180;

Wang B, Lunetta KL, Dupuis J, Lubitz SA, Trinquart L, Yao L, Ellinor PT, Benjamin EJ, Lin H. Integrative Omics Approach to Identifying Genes Associated With Atrial Fibrillation. Circ Res. 2020 01 31; 126(3):350-360.View Related Profiles.

Wang, Biqi
Benjamin, Emelia
Lin, Honghuang
Dupuis, Josee
Lunetta, Kathryn
Trinquart, Ludovic

PMID: 31801406; PMCID: PMC7004281; DOI: 10.1161/CIRCRESAHA.119.315179;

Choi SH, Jurgens SJ, Weng LC, Pirruccello JP, Roselli C, Chaffin M, Lee CJ, Hall AW, Khera AV, Lunetta KL, Lubitz SA, Ellinor PT. Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results From a National Biobank. Circ Res. 2020 01 17; 126(2):200-209.View Related Profiles.

Lunetta, Kathryn
Choi, Seung Hoan

PMID: 31691645; PMCID: PMC7007701; DOI: 10.1161/CIRCRESAHA.119.315686;

Bae H, Lunetta KL, Murabito JM, Andersen SL, Schupf N, Perls T, Sebastiani P. Genetic associations with age of menopause in familial longevity. Menopause. 2019 10; 26(10):1204-1212.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Sebastiani, Paola
Andersen, Stacy
Perls, Thomas

PMID: 31188284; PMCID: PMC7008937; DOI: 10.1097/GME.0000000000001367;

Spartano NL, Lin H, Sun F, Lunetta KL, Trinquart L, Valentino M, Manders ES, Pletcher MJ, Marcus GM, McManus DD, Benjamin EJ, Fox CS, Olgin JE, Murabito JM. Comparison of On-Site Versus Remote Mobile Device Support in the Framingham Heart Study Using the Health eHeart Study for Digital Follow-up: Randomized Pilot Study Set Within an Observational Study Design. JMIR Mhealth Uhealth. 2019 09 30; 7(9):e13238.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn
Trinquart, Ludovic
Spartano, Nicole

PMID: 31573928; PMCID: PMC6792023; DOI: 10.2196/13238;

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roshchupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Uitterlinden AGA, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. Author CoView Related Profiles.

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DeStefano, Anita
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Himali, Jayandra
Lunetta, Kathryn
Cupples, L
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Kowall, Neil
Yang, Qiong
Stern, Robert
Seshadri, Sudha

PMID: 31417202; PMCID: PMC7265117; DOI: 10.1038/s41588-019-0495-7;

Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW, Bis JC, Debette S, DeStefano AL, Fornage M, Nicolas G, van Duijn C, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Seshadri S, Lambert JC, Schellenberg GD, Lunetta KL, Farrer LA. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. JAMA Neurol. 2019 Sep 01; 76(9):1099-1108.View Related Profiles.

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Zhang, Xiaoling

PMID: 31180460; PMCID: PMC6563544; DOI: 10.1001/jamaneurol.2019.1456;

Lin H, Rogers GT, Lunetta KL, Levy D, Miao X, Troy LM, Jacques PF, Murabito JM. Healthy diet is associated with gene expression in blood: the Framingham Heart Study. Am J Clin Nutr. 2019 09 01; 110(3):742-749.View Related Profiles.

Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn

PMID: 31187853; PMCID: PMC6736078; DOI: 10.1093/ajcn/nqz060;

Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, Chong A, Byun MS, Seo S, Ko PW, Han JW, McLean C, Farrell J, Lunetta KL, Miyashita A, Hara N, Won S, Choi SM, Ha JM, Jeong JH, Kuwano R, Song MK, An SSA, Lee YM, Park KW, Lee HW, Choi SH, Rhee S, Song WK, Lee JS, Mayeux R, Haines JL, Pericak-Vance MA, Choo ILH, Nho K, Kim KW, Lee DY, Kim S, Kim BC, Kim H, Jun GR, Schellenberg GD, Ikeuchi T, Farrer LA, Lee KH, Neuroimaging Initative AD. APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE e4 on Alzheimer's Disease Risk in a Multiracial Sample. J Clin Med. 2019 Aug 16; 8(8).View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Zhang, Xiaoling

PMID: 31426376; PMCID: PMC6723529; DOI: 10.3390/jcm8081236;

Deelen J, Evans DS, Arking DE, Tesi N, Nygaard M, Liu X, Wojczynski MK, Biggs ML, van der Spek A, Atzmon G, Ware EB, Sarnowski C, Smith AV, Seppälä I, Cordell HJ, Dose J, Amin N, Arnold AM, Ayers KL, Barzilai N, Becker EJ, Beekman M, Blanché H, Christensen K, Christiansen L, Collerton JC, Cubaynes S, Cummings SR, Davies K, Debrabant B, Deleuze JF, Duncan R, Faul JD, Franceschi C, Galan P, Gudnason V, Harris TB, Huisman M, Hurme MA, Jagger C, Jansen I, Jylhä M, Kähönen M, Karasik D, Kardia SLR, Kingston A, Kirkwood TBL, Launer LJ, Lehtimäki T, Lieb W, Lyytikäinen LP, Martin-Ruiz C, Min J, Nebel A, Newman AB, Nie C, Nohr EA, Orwoll ES, Perls TT, Province MA, Psaty BM, Raitakari OT, Reinders MJT, Robine JM, Rotter JI, Sebastiani P, Smith J, Sørensen TIA, Taylor KD, Uitterlinden AG, van der Flier W, van der Lee SJ, van Duijn CM, van Heemst D, Vaupel JW, Weir D, Ye K, Zeng Y, Zheng W, Holstege H, Kiel DP, Lunetta KL, Slagboom PE, Murabito JM. A meta-analysis of genome-wide association studies identifies multiple longevity genes. Nat Commun. 2019 08 14; 10(1):3669.View Related Profiles.

Sarnowski, Chloe
Murabito, Joanne
Lunetta, Kathryn
Sebastiani, Paola
Perls, Thomas

PMID: 31413261; PMCID: PMC6694136; DOI: 10.1038/s41467-019-11558-2;

Conner SC, Lodi S, Lunetta KL, Casas JP, Lubitz SA, Ellinor PT, Anderson CD, Huang Q, Coleman J, White WB, Benjamin EJ, Trinquart L. Refining the Association Between Body Mass Index and Atrial Fibrillation: G-Formula and Restricted Mean Survival Times. J Am Heart Assoc. 2019 08 20; 8(16):e013011.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Trinquart, Ludovic
Lodi, Sara

PMID: 31390924; PMCID: PMC6759878; DOI: 10.1161/JAHA.119.013011;

Zhou Z, Lunetta KL, Smith AK, Wolf EJ, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Miller MW, Logue MW. Correction for multiple testing in candidate-gene methylation studies. Epigenomics. 2019 07; 11(9):1089-1105.View Related Profiles.

Wolf, Erika
Lunetta, Kathryn
Logue, Mark
Miller, Mark
McGlinchey, Regina
Milberg, William

PMID: 31240951; PMCID: PMC7132638; DOI: 10.2217/epi-2018-0204;

Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, Lunetta KL. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. 2019 08; 18(4):e12964.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Lunetta, Kathryn
Farrer, Lindsay
Zhang, Xiaoling

PMID: 31144443; PMCID: PMC6612647; DOI: 10.1111/acel.12964;

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Qiao Z, Moen GH, Vaudel M, Marsit CJ, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga JJ, Lyytikäinen LP, Cavadino A, Metrustry S, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Richmond RC, Espinosa A, Barton SJ, Inskip HM, Holloway JW, Santa-Marina L, Estivill X, Ang W, Marsh JA, Reichetzeder C, Marullo L, Hocher B, Lunetta KL, Murabito JM, Relton CL, Kogevinas M, Chatzi L, Allard C, Bouchard L, Hivert MF, Zhang G, Muglia LJ, Heikkinen J, Morgen CS, van Kampen AHC, van Schaik BDC, Mentch FD, Langenberg C, Luan J, Scott RA, Zhao JH, Hemani G, Ring SM, Bennett AJ, Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Das S, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, van Beijsterveldt CEM, Murcia M, Bustamante M, Bonas-Guarch S, Hougaard DM, Mercader JM, Linneberg A, Schraut KE, Lind PA, Medland SE, Shields BM, Knight BA, Chai JF, Panoutsopoulou K, Bartels M, Sánchez F, Stokholm J, Torrents D, Vinding RK, Willems SM, Atalay M, Chawes BL, Kovacs P, Prokopenko I, Tuke MA, Yaghootkar H, Ruth KS, Jones SE, Loh PR, Murray A, Weedon MN, Tönjes A, Stumvoll M, Michaelsen KF, Eloranta AM, Lakka TA, van Duijn CM, Kiess W, Körner A, Niinikoski H, Pahkala K, Raitakari OT, Jacobsson B, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Montgomery GW, Campbell H, Wilson JF, Vrijkotte TGM, Vrijheid M, de Geus EJCN, Hayes MG, Kadarmideen HN, Holm JC, Beilin LJ, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Hattersley AT, Spector TD, Kähönen M, Viikari JS, Lehtimäki T, Boomsma DI, Sebert S, Vollenweider P, Sørensen TIA, Bisgaard H, Bønnelykke K, Murray JC, Melbye M, Nohr EA, Mook-Kanamori DO, Rivadeneira F, Hofman A, Felix JF, Jaddoe VWV, Hansen T, Pisinger C, Vaag AA, Pedersen O, Uitterlinden AG, Järvelin MR, Power C, Hyppönen E, Scholtens DM, Lowe WL, Davey Smith G, Timpson NJ, Morris AP, Wareham NJ, Hakonarson H, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JRB, Evans DM, Freathy RM. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nat Genet. 2019 05; 51(5):804-814.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 31043758; PMCID: PMC6522365; DOI: 10.1038/s41588-019-0403-1;

Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell JJ, Rynkiewicz MJ, Cannon-Albright LA, Teerlink CC, Stevens J, Corcoran C, Gonzalez Murcia JD, Lopez OL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg G, Kauwe JSK, Lunetta KL, Farrer LA. Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry. JAMA Netw Open. 2019 03 01; 2(3):e191350.View Related Profiles.

Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Rynkiewicz, Michael
Zhang, Xiaoling

PMID: 30924900; PMCID: PMC6450321; DOI: 10.1001/jamanetworkopen.2019.1350;

Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, Badarinarayan N, Jakobsdottir J, Hamilton-Nelson KL, Moreno-Grau S, Olaso R, Raybould R, Chen Y, Kuzma AB, Hiltunen M, Morgan T, Ahmad S, Vardarajan BN, Epelbaum J, Hoffmann P, Boada M, Beecham GW, Garnier JG, Harold D, Fitzpatrick AL, Valladares O, Moutet ML, Gerrish A, Smith AV, Qu L, Bacq D, Denning N, Jian X, Zhao Y, Del Zompo M, Fox NC, Choi SH, Mateo I, Hughes JT, Adams HH, Malamon J, Sanchez-Garcia F, Patel Y, Brody JA, Dombroski BA, Naranjo MCD, Daniilidou M, Eiriksdottir G, Mukherjee S, Wallon D, Uphill J, Aspelund T, Cantwell LB, Garzia F, Galimberti D, Hofer E, Butkiewicz M, Fin B, Scarpini E, Sarnowski C, Bush WS, Meslage S, Kornhuber J, White CC, Song Y, Barber RC, Engelborghs S, Sordon S, Voijnovic D, Adams PM, Vandenberghe R, Mayhaus M, Cupples LA, Albert MS, De Deyn PP, Gu W, Himali JJ, Beekly D, Squassina A, Hartmann AM, Orellana A, Blacker D, Rodriguez-Rodriguez E, Lovestone S, Garcia ME, Doody RS, Munoz-Fernadez C, Sussams R, Lin H, Fairchild TJ, Benito YA, Holmes C, Karamujic-Comic H, Frosch MP, Thonberg H, Maier W, Roschupkin G, Ghetti B, Giedraitis V, Kawalia A, Li S, Huebinger RM, Kilander L, Moebus S, Hernández I, Kamboh MI, Brundin R, Turton J, Yang Q, Katz MJ, Concari L, Lord J, Beiser AS, Keene CD, Helisalmi S, Kloszewska I, Kukull WA, Koivisto AM, Lynch A, Tarraga L, Larson EB, Haapasalo A, Lawlor B, Mosley TH, Lipton RB, Solfrizzi V, Gill M, Longstreth WT, Montine TJ, Frisardi V, Diez-Fairen M, Rivadeneira F, Petersen RC, Deramecourt V, Alvarez I, Salani F, Ciaramella A, Boerwinkle E, Reiman EM, Fievet N, Rotter JI, Reisch JS, Hanon O, Cupidi C, Andre Uitterlinden AG, Royall DR, Dufouil C, Maletta RG, de Rojas I, Sano M, Brice A, Cecchetti R, George-Hyslop PS, Ritchie K, Tsolaki M, Tsuang DW, Dubois B, Craig D, Wu CK, Soininen H, Avramidou D, Albin RL, Fratiglioni L, Germanou A, Apostolova LG, Keller L, Koutroumani M, Arnold SE, Panza F, Gkatzima O, Asthana S, Hannequin D, Whitehead P, Atwood CS, Caffarra P, Hampel H, Quintela I, Carracedo Á, Lannfelt L, Rubinsztein DC, Barnes LL, Pasquier F, Frölich L, Barral S, McGuinness B, Beach TG, Johnston JA, Becker JT, Passmore P, Bigio EH, Schott JM, Bird TD, Warren JD, Boeve BF, Lupton MK, Bowen JD, Proitsi P, Boxer A, Powell JF, Burke JR, Kauwe JSK, Burns JM, Mancuso M, Buxbaum JD, Bonuccelli U, Cairns NJ, McQuillin A, Cao C, Livingston G, Carlson CS, Bass NJ, Carlsson CM, Hardy J, Carney RM, Bras J, Carrasquillo MM, Guerreiro R, Allen M, Chui HC, Fisher E, Masullo C, Crocco EA, DeCarli C, Bisceglio G, Dick M, Ma L, Duara R, Graff-Radford NR, Evans DA, Hodges A, Faber KM, Scherer M, Fallon KB, Riemenschneider M, Fardo DW, Heun R, Farlow MR, Kölsch H, Ferris S, Leber M, Foroud TM, Heuser I, Galasko DR, Giegling I, Gearing M, Hüll M, Geschwind DH, Gilbert JR, Morris J, Green RC, Mayo K, Growdon JH, Feulner T, Hamilton RL, Harrell LE, Drichel D, Honig LS, Cushion TD, Huentelman MJ, Hollingworth P, Hulette CM, Hyman BT, Marshall R, Jarvik GP, Meggy A, Abner E, Menzies GE, Jin LW, Leonenko G, Real LM, Jun GR, Baldwin CT, Grozeva D, Karydas A, Russo G, Kaye JA, Kim R, Jessen F, Kowall NW, Vellas B, Kramer JH, Vardy E, LaFerla FM, Jöckel KH, Lah JJ, Dichgans M, Leverenz JB, Mann D, Levey AI, Pickering-Brown S, Lieberman AP, Klopp N, Lunetta KL, Wichmann HE, Lyketsos CG, Morgan K, Marson DC, Brown K, Martiniuk F, Medway C, Mash DC, Nöthen MM, Masliah E, Hooper NM, McCormick WC, Daniele A, McCurry SM, Bayer A, McDavid AN, Gallacher J, McKee AC, van den Bussche H, Mesulam M, Brayne C, Miller BL, Riedel-Heller S, Miller CA, Miller JW, Al-Chalabi A, Morris JC, Shaw CE, Myers AJ, Wiltfang J, O'Bryant S, Olichney JM, Alvarez V, Parisi JE, Singleton AB, Paulson HL, Collinge J, Perry WR, Mead S, Peskind E, Cribbs DH, Rossor M, Pierce A, Ryan NS, Poon WW, Nacmias B, Potter H, Sorbi S, et al. GenetView Related Profiles.

Beiser, Alexa
DeStefano, Anita
McKee, Ann
Sarnowski, Chloe
Jun, Gyungah
Lin, Honghuang
Himali, Jayandra
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil
Yang, Qiong
Stern, Robert
Seshadri, Sudha

PMID: 30820047; PMCID: PMC6463297; DOI: 10.1038/s41588-019-0358-2;

Orkaby AR, Lunetta KL, Sun FJ, Driver JA, Benjamin EJ, Hamburg NM, Mitchell GF, Vasan RS, Murabito JM. Cross-Sectional Association of Frailty and Arterial Stiffness in Community-Dwelling Older Adults: The Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):373-379.View Related Profiles.

Orkaby, Ariela
Benjamin, Emelia
Murabito, Joanne
Lunetta, Kathryn
Hamburg, Naomi

PMID: 29917058; PMCID: PMC6599281; DOI: 10.1093/gerona/gly134;

Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA. A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease. Alzheimers Dement. 2019 03; 15(3):441-452.View Related Profiles.

Chung, Jaeyoon
Lunetta, Kathryn
Farrer, Lindsay
Zhang, Xiaoling

PMID: 30503768; PMCID: PMC6408965; DOI: 10.1016/j.jalz.2018.10.005;

Zhao Q, Zhang B, LaValley MP, Massaro JM, Lunetta KL, Chang M. . Extended Rank Tests for Analyzing Recurrent Event Data. Statistics in Biopharmaceutical Research. 2019. View Publication

Lin H, Lunetta KL, Zhao Q, Mandaviya PR, Rong J, Benjamin EJ, Joehanes R, Levy D, van Meurs JBJ, Larson MG, Murabito JM. Whole Blood Gene Expression Associated With Clinical Biological Age. J Gerontol A Biol Sci Med Sci. 2019 01 01; 74(1):81-88.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn
Larson, Martin

PMID: 30010802; PMCID: PMC6298179; DOI: 10.1093/gerona/gly164;

Choi SH, Weng LC, Roselli C, Lin H, Haggerty CM, Shoemaker MB, Barnard J, Arking DE, Chasman DI, Albert CM, Chaffin M, Tucker NR, Smith JD, Gupta N, Gabriel S, Margolin L, Shea MA, Shaffer CM, Yoneda ZT, Boerwinkle E, Smith NL, Silverman EK, Redline S, Vasan RS, Burchard EG, Gogarten SM, Laurie C, Blackwell TW, Abecasis G, Carey DJ, Fornwalt BK, Smelser DT, Baras A, Dewey FE, Jaquish CE, Papanicolaou GJ, Sotoodehnia N, Van Wagoner DR, Psaty BM, Kathiresan S, Darbar D, Alonso A, Heckbert SR, Chung MK, Roden DM, Benjamin EJ, Murray MF, Lunetta KL, Lubitz SA, Ellinor PT. Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation. JAMA. 2018 12 11; 320(22):2354-2364.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Choi, Seung Hoan

PMID: 30535219; PMCID: PMC6436530; DOI: 10.1001/jama.2018.18179;

Logue MW, Lancour D, Farrell J, Simkina I, Fallin MD, Lunetta KL, Farrer LA. Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants. Front Neurosci. 2018; 12:592.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark

PMID: 30210277; PMCID: PMC6119822; DOI: 10.3389/fnins.2018.00592;

Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, Amin N, Amouyel P, Beecham GW, Below JE, Campion D, Cantwell L, Charbonnier C, Chung J, Crane PK, Cruchaga C, Cupples LA, Dartigues JF, Debette S, Deleuze JF, Fulton L, Gabriel SB, Genin E, Gibbs RA, Goate A, Grenier-Boley B, Gupta N, Haines JL, Havulinna AS, Helisalmi S, Hiltunen M, Howrigan DP, Ikram MA, Kaprio J, Konrad J, Kuzma A, Lander ES, Lathrop M, Lehtimäki T, Lin H, Mattila K, Mayeux R, Muzny DM, Nasser W, Neale B, Nho K, Nicolas G, Patel D, Pericak-Vance MA, Perola M, Psaty BM, Quenez O, Rajabli F, Redon R, Reitz C, Remes AM, Salomaa V, Sarnowski C, Schmidt H, Schmidt M, Schmidt R, Soininen H, Thornton TA, Tosto G, Tzourio C, van der Lee SJ, van Duijn CM, Valladares O, Vardarajan B, Wang LS, Wang W, Wijsman E, Wilson RK, Witten D, Worley KC, Zhang X, Bellenguez C, Lambert JC, Kurki MI, Palotie A, Daly M, Boerwinkle E, Lunetta KL, Destefano AL, Dupuis J, Martin ER, Schellenberg GD, Seshadri S, Naj AC, Fornage M, Farrer LA. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Mol Psychiatry. 2020 08; 25(8):1859-1875.View Related Profiles.

DeStefano, Anita
Sarnowski, Chloe
Lin, Honghuang
Chung, Jaeyoon
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Seshadri, Sudha
Zhang, Xiaoling

PMID: 30108311; PMCID: PMC6375806; DOI: 10.1038/s41380-018-0112-7;

Roselli C, Chaffin MD, Weng LC, Aeschbacher S, Ahlberg G, Albert CM, Almgren P, Alonso A, Anderson CD, Aragam KG, Arking DE, Barnard J, Bartz TM, Benjamin EJ, Bihlmeyer NA, Bis JC, Bloom HL, Boerwinkle E, Bottinger EB, Brody JA, Calkins H, Campbell A, Cappola TP, Carlquist J, Chasman DI, Chen LY, Chen YI, Choi EK, Choi SH, Christophersen IE, Chung MK, Cole JW, Conen D, Cook J, Crijns HJ, Cutler MJ, Damrauer SM, Daniels BR, Darbar D, Delgado G, Denny JC, Dichgans M, Dörr M, Dudink EA, Dudley SC, Esa N, Esko T, Eskola M, Fatkin D, Felix SB, Ford I, Franco OH, Geelhoed B, Grewal RP, Gudnason V, Guo X, Gupta N, Gustafsson S, Gutmann R, Hamsten A, Harris TB, Hayward C, Heckbert SR, Hernesniemi J, Hocking LJ, Hofman A, Horimoto ARVR, Huang J, Huang PL, Huffman J, Ingelsson E, Ipek EG, Ito K, Jimenez-Conde J, Johnson R, Jukema JW, Kääb S, Kähönen M, Kamatani Y, Kane JP, Kastrati A, Kathiresan S, Katschnig-Winter P, Kavousi M, Kessler T, Kietselaer BL, Kirchhof P, Kleber ME, Knight S, Krieger JE, Kubo M, Launer LJ, Laurikka J, Lehtimäki T, Leineweber K, Lemaitre RN, Li M, Lim HE, Lin HJ, Lin H, Lind L, Lindgren CM, Lokki ML, London B, Loos RJF, Low SK, Lu Y, Lyytikäinen LP, Macfarlane PW, Magnusson PK, Mahajan A, Malik R, Mansur AJ, Marcus GM, Margolin L, Margulies KB, März W, McManus DD, Melander O, Mohanty S, Montgomery JA, Morley MP, Morris AP, Müller-Nurasyid M, Natale A, Nazarian S, Neumann B, Newton-Cheh C, Niemeijer MN, Nikus K, Nilsson P, Noordam R, Oellers H, Olesen MS, Orho-Melander M, Padmanabhan S, Pak HN, Paré G, Pedersen NL, Pera J, Pereira A, Porteous D, Psaty BM, Pulit SL, Pullinger CR, Rader DJ, Refsgaard L, Ribasés M, Ridker PM, Rienstra M, Risch L, Roden DM, Rosand J, Rosenberg MA, Rost N, Rotter JI, Saba S, Sandhu RK, Schnabel RB, Schramm K, Schunkert H, Schurman C, Scott SA, Seppälä I, Shaffer C, Shah S, Shalaby AA, Shim J, Shoemaker MB, Siland JE, Sinisalo J, Sinner MF, Slowik A, Smith AV, Smith BH, Smith JG, Smith JD, Smith NL, Soliman EZ, Sotoodehnia N, Stricker BH, Sun A, Sun H, Svendsen JH, Tanaka T, Tanriverdi K, Taylor KD, Teder-Laving M, Teumer A, Thériault S, Trompet S, Tucker NR, Tveit A, Uitterlinden AG, Van Der Harst P, Van Gelder IC, Van Wagoner DR, Verweij N, Vlachopoulou E, Völker U, Wang B, Weeke PE, Weijs B, Weiss R, Weiss S, Wells QS, Wiggins KL, Wong JA, Woo D, Worrall BB, Yang PS, Yao J, Yoneda ZT, Zeller T, Zeng L, Lubitz SA, Lunetta KL, Ellinor PT. Multi-ethnic genome-wide association study for atrial fibrillation. Nat Genet. 2018 06 11; 50(9):1225-1233.View Related Profiles.

Wang, Biqi
Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Choi, Seung Hoan

PMID: 29892015; PMCID: PMC6136836; DOI: 10.1038/s41588-018-0133-9;

Yao S, Hong CC, Ruiz-Narváez EA, Evans SS, Zhu Q, Schaefer BA, Yan L, Coignet MV, Lunetta KL, Sucheston-Campbell LE, Lee K, Bandera EV, Troester MA, Rosenberg L, Palmer JR, Olshan AF, Ambrosone CB. Genetic ancestry and population differences in levels of inflammatory cytokines in women: Role for evolutionary selection and environmental factors. PLoS Genet. 2018 06; 14(6):e1007368.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn

PMID: 29879116; PMCID: PMC5991662; DOI: 10.1371/journal.pgen.1007368;

Bensen JT, Graff M, Young KL, Sethupathy P, Parker J, Pecot CV, Currin K, Haddad SA, Ruiz-Narváez EA, Haiman CA, Hong CC, Sucheston-Campbell LE, Zhu Q, Liu S, Yao S, Bandera EV, Rosenberg L, Lunetta KL, Ambrosone CB, Palmer JR, Troester MA, Olshan AF. A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women. Breast Cancer Res. 2018 06 05; 20(1):45.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn

PMID: 29871690; PMCID: PMC5989404; DOI: 10.1186/s13058-018-0964-4;

Murabito JM, Zhao Q, Larson MG, Rong J, Lin H, Benjamin EJ, Levy D, Lunetta KL. Measures of Biologic Age in a Community Sample Predict Mortality and Age-Related Disease: The Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2018 05 09; 73(6):757-762.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn
Larson, Martin

PMID: 28977464; PMCID: PMC5946832; DOI: 10.1093/gerona/glx144;

Staerk L, Wang B, Preis SR, Larson MG, Lubitz SA, Ellinor PT, McManus DD, Ko D, Weng LC, Lunetta KL, Frost L, Benjamin EJ, Trinquart L. Lifetime risk of atrial fibrillation according to optimal, borderline, or elevated levels of risk factors: cohort study based on longitudinal data from the Framingham Heart Study. BMJ. 2018 04 26; 361:k1453.View Related Profiles.

Wang, Biqi
Ko, Darae
Benjamin, Emelia
Lunetta, Kathryn
Trinquart, Ludovic
Larson, Martin
Preis, Sarah

PMID: 29699974; PMCID: PMC5917175; DOI: 10.1136/bmj.k1453;

Sarnowski C, Kavousi M, Isaacs S, Demerath EW, Broer L, Muka T, Franco OH, Ikram MA, Uitterlinden A, Franceschini N, Lunetta KL, Murabito JM. Genetic variants associated with earlier age at menopause increase the risk of cardiovascular events in women. Menopause. 2018 04; 25(4):451-457.View Related Profiles.

Sarnowski, Chloe
Murabito, Joanne
Lunetta, Kathryn

PMID: 29112599; PMCID: PMC5866156; DOI: 10.1097/GME.0000000000001017;

Ikezu T, Chen C, DeLeo AM, Zeldich E, Fallin MD, Kanaan NM, Lunetta KL, Abraham CR, Logue MW, Farrer LA. Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans. J Neuroimmune Pharmacol. 2018 06; 13(2):254-264.View Related Profiles.

Abraham, Carmela
Zeldich, Ella
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Ikezu, Tsuneya

PMID: 29516269; PMCID: PMC5928172; DOI: 10.1007/s11481-018-9781-x;

Eriksson AL, Perry JRB, Coviello AD, Delgado GE, Ferrucci L, Hoffman AR, Huhtaniemi IT, Ikram MA, Karlsson MK, Kleber ME, Laughlin GA, Liu Y, Lorentzon M, Lunetta KL, Mellström D, Murabito JM, Murray A, Nethander M, Nielson CM, Prokopenko I, Pye SR, Raffel LJ, Rivadeneira F, Srikanth P, Stolk L, Teumer A, Travison TG, Uitterlinden AG, Vaidya D, Vanderschueren D, Zmuda JM, März W, Orwoll ES, Ouyang P, Vandenput L, Wu FCW, de Jong FH, Bhasin S, Kiel DP, Ohlsson C. Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men. J Clin Endocrinol Metab. 2018 03 01; 103(3):991-1004.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 29325096; PMCID: PMC5868407; DOI: 10.1210/jc.2017-02060;

Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, Jun G, Kunkle B, Kuzma A, Lee JJ, Lunetta KL, Ma Y, Martin E, Naj A, Nato AQ, Navas P, Nguyen H, Reitz C, Reyes D, Salerno W, Schellenberg GD, Seshadri S, Sohi H, Thornton TA, Valadares O, van Duijn C, Vardarajan BN, Wang LS, Boerwinkle E, Dupuis J, Pericak-Vance MA, Mayeux R, Wijsman EM. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dement Geriatr Cogn Disord. 2018; 45(1-2):1-17.View Related Profiles.

DeStefano, Anita
Jun, Gyungah
Dupuis, Josee
Lunetta, Kathryn
Farrer, Lindsay
Seshadri, Sudha

PMID: 29486463; PMCID: PMC5971141; DOI: 10.1159/000485503;

Chung J, Zhang X, Allen M, Wang X, Ma Y, Beecham G, Montine TJ, Younkin SG, Dickson DW, Golde TE, Price ND, Ertekin-Taner N, Lunetta KL, Mez J, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg G, Jun GR, Farrer LA. Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Alzheimers Res Ther. 2018 02 20; 10(1):22.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Zhang, Xiaoling

PMID: 29458411; PMCID: PMC5819208; DOI: 10.1186/s13195-018-0349-z;

Beaumont RN, Warrington NM, Cavadino A, Tyrrell J, Nodzenski M, Horikoshi M, Geller F, Myhre R, Richmond RC, Paternoster L, Bradfield JP, Kreiner-Møller E, Huikari V, Metrustry S, Lunetta KL, Painter JN, Hottenga JJ, Allard C, Barton SJ, Espinosa A, Marsh JA, Potter C, Zhang G, Ang W, Berry DJ, Bouchard L, Das S, Hakonarson H, Heikkinen J, Helgeland Ø, Hocher B, Hofman A, Inskip HM, Jones SE, Kogevinas M, Lind PA, Marullo L, Medland SE, Murray A, Murray JC, Njølstad PR, Nohr EA, Reichetzeder C, Ring SM, Ruth KS, Santa-Marina L, Scholtens DM, Sebert S, Sengpiel V, Tuke MA, Vaudel M, Weedon MN, Willemsen G, Wood AR, Yaghootkar H, Muglia LJ, Bartels M, Relton CL, Pennell CE, Chatzi L, Estivill X, Holloway JW, Boomsma DI, Montgomery GW, Murabito JM, Spector TD, Power C, Järvelin MR, Bisgaard H, Grant SFA, Sørensen TIA, Jaddoe VW, Jacobsson B, Melbye M, McCarthy MI, Hattersley AT, Hayes MG, Frayling TM, Hivert MF, Felix JF, Hyppönen E, Lowe WL, Evans DM, Lawlor DA, Feenstra B, Freathy RM. Genome-wide association study of offspring birth weight in 86?577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. Hum Mol Genet. 2018 02 15; 27(4):742-756.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 29309628; PMCID: PMC5886200; DOI: 10.1093/hmg/ddx429;

Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, Marioni RE, Visscher PM, Wray NR, Deary IJ, Levine ME, Quach A, Assimes T, Tsao PS, Absher D, Stewart JD, Li Y, Reiner AP, Hou L, Baccarelli AA, Whitsel EA, Aviv A, Cardona A, Day FR, Wareham NJ, Perry JRB, Ong KK, Raj K, Lunetta KL, Horvath S. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nat Commun. 2018 01 26; 9(1):387.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 29374233; PMCID: PMC5786029; DOI: 10.1038/s41467-017-02697-5;

Hong CC, Sucheston-Campbell LE, Liu S, Hu Q, Yao S, Lunetta KL, Haddad SA, Ruiz-Narváez EA, Bensen JT, Cheng TD, Bandera EV, Rosenberg LA, Haiman CA, Lee K, Evans SS, Abrams SI, Repasky EA, Olshan AF, Palmer JR, Ambrosone CB. Genetic Variants in Immune-Related Pathways and Breast Cancer Risk in African American Women in the AMBER Consortium. Cancer Epidemiol Biomarkers Prev. 2018 03; 27(3):321-330.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn
Rosenberg, Lynn

PMID: 29339359; PMCID: PMC5835191; DOI: 10.1158/1055-9965.EPI-17-0434;

Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Lunetta KL, Farrer LA, Jun GR. Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages. Alzheimers Dement. 2018 05; 14(5):623-633.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Sherva, Richard
Zhang, Xiaoling

PMID: 29274321; PMCID: PMC5938137; DOI: 10.1016/j.jalz.2017.11.006;

Weng LC, Choi SH, Klarin D, Smith JG, Loh PR, Chaffin M, Roselli C, Hulme OL, Lunetta KL, Dupuis J, Benjamin EJ, Newton-Cheh C, Kathiresan S, Ellinor PT, Lubitz SA. Heritability of Atrial Fibrillation. Circ Cardiovasc Genet. 2017 Dec; 10(6).View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Choi, Seung Hoan

PMID: 29237688; PMCID: PMC5966046; DOI: 10.1161/CIRCGENETICS.117.001838;

Staerk L, Wang B, Lunetta KL, Helm RH, Ko D, Sherer JA, Ellinor PT, Lubitz SA, McManus DD, Vasan RS, Benjamin EJ, Trinquart L. Association Between Leukocyte Telomere Length and the Risk of Incident Atrial Fibrillation: The Framingham Heart Study. J Am Heart Assoc. 2017 Nov 14; 6(11).View Related Profiles.

Wang, Biqi
Ko, Darae
Benjamin, Emelia
Sherer, Jason
Lunetta, Kathryn
Trinquart, Ludovic
Helm, Robert
Ramachandran, Vasan

PMID: 29138179; PMCID: PMC5721755; DOI: 10.1161/JAHA.117.006541;

Weng LC, Preis SR, Hulme OL, Larson MG, Choi SH, Wang B, Trinquart L, McManus DD, Staerk L, Lin H, Lunetta KL, Ellinor PT, Benjamin EJ, Lubitz SA. Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation. Circulation. 2018 03 06; 137(10):1027-1038.View Related Profiles.

Wang, Biqi
Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Trinquart, Ludovic
Larson, Martin
Preis, Sarah
Choi, Seung Hoan

PMID: 29129827; PMCID: PMC5840011; DOI: 10.1161/CIRCULATIONAHA.117.031431;

Lin H, Lunetta KL, Zhao Q, Rong J, Benjamin EJ, Mendelson MM, Joehanes R, Levy D, Larson MG, Murabito JM. Transcriptome-wide association study of inflammatory biologic age. Aging (Albany NY). 2017 Nov 11; 9(11):2288-2301.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn
Larson, Martin

PMID: 29135455; PMCID: PMC5723687; DOI: 10.18632/aging.101321;

Tucker NR, Dolmatova EV, Lin H, Cooper RR, Ye J, Hucker WJ, Jameson HS, Parsons VA, Weng LC, Mills RW, Sinner MF, Imakaev M, Leyton-Mange J, Vlahakes G, Benjamin EJ, Lunetta KL, Lubitz SA, Mirny L, Milan DJ, Ellinor PT. Diminished PRRX1 Expression Is Associated With Increased Risk of Atrial Fibrillation and Shortening of the Cardiac Action Potential. Circ Cardiovasc Genet. 2017 Oct; 10(5).View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn

PMID: 28974514; PMCID: PMC5679717; DOI: 10.1161/CIRCGENETICS.117.001902;

Tanaka T, Dutta A, Pilling LC, Xue L, Lunetta KL, Murabito JM, Bandinelli S, Wallace R, Melzer D, Ferrucci L. Genome-wide Association Study of Parental Life Span. J Gerontol A Biol Sci Med Sci. 2017 Oct 01; 72(10):1407-1410.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 27816938; PMCID: PMC5861941; DOI: 10.1093/gerona/glw206;

Weng LC, Lunetta KL, Müller-Nurasyid M, Smith AV, Thériault S, Weeke PE, Barnard J, Bis JC, Lyytikäinen LP, Kleber ME, Martinsson A, Lin HJ, Rienstra M, Trompet S, Krijthe BP, Dörr M, Klarin D, Chasman DI, Sinner MF, Waldenberger M, Launer LJ, Harris TB, Soliman EZ, Alonso A, Paré G, Teixeira PL, Denny JC, Shoemaker MB, Van Wagoner DR, Smith JD, Psaty BM, Sotoodehnia N, Taylor KD, Kähönen M, Nikus K, Delgado GE, Melander O, Engström G, Yao J, Guo X, Christophersen IE, Ellinor PT, Geelhoed B, Verweij N, Macfarlane P, Ford I, Heeringa J, Franco OH, Uitterlinden AG, Völker U, Teumer A, Rose LM, Kääb S, Gudnason V, Arking DE, Conen D, Roden DM, Chung MK, Heckbert SR, Benjamin EJ, Lehtimäki T, März W, Smith JG, Rotter JI, van der Harst P, Jukema JW, Stricker BH, Felix SB, Albert CM, Lubitz SA. Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium. Sci Rep. 2017 09 12; 7(1):11303.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 28900195; PMCID: PMC5595875; DOI: 10.1038/s41598-017-09396-7;

Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, R V R Horimoto A, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Nikus K, Orho-Melander M, Hamsten A, Heeringa J, Denny JC, Kriebel J, Darbar D, Newton-Cheh C, Shaffer C, Macfarlane PW, Heilmann-Heimbach S, Almgren P, Huang PL, Sotoodehnia N, Soliman EZ, Uitterlinden AG, Hofman A, Franco OH, Völker U, Jöckel KH, Sinner MF, Lin HJ, Guo X, Dichgans M, Ingelsson E, Kooperberg C, Melander O, J F Loos R, Laurikka J, Conen D, Rosand J, van der Harst P, Lokki ML, Kathiresan S, Pereira A, Jukema JW, Hayward C, Rotter JI, März W, Lehtimäki T, Stricker BH, Chung MK, Felix SB, Gudnason V, Alonso A, Roden DM, Kääb S, Chasman DI, Heckbert SR, Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT. Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017 07 27; 49(8):1286.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 28747752

Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, Sleegers K, Vronskaya M, Ruiz A, Graham RR, Olaso R, Hoffmann P, Grove ML, Vardarajan BN, Hiltunen M, Nöthen MM, White CC, Hamilton-Nelson KL, Epelbaum J, Maier W, Choi SH, Beecham GW, Dulary C, Herms S, Smith AV, Funk CC, Derbois C, Forstner AJ, Ahmad S, Li H, Bacq D, Harold D, Satizabal CL, Valladares O, Squassina A, Thomas R, Brody JA, Qu L, Sánchez-Juan P, Morgan T, Wolters FJ, Zhao Y, Garcia FS, Denning N, Fornage M, Malamon J, Naranjo MCD, Majounie E, Mosley TH, Dombroski B, Wallon D, Lupton MK, Dupuis J, Whitehead P, Fratiglioni L, Medway C, Jian X, Mukherjee S, Keller L, Brown K, Lin H, Cantwell LB, Panza F, McGuinness B, Moreno-Grau S, Burgess JD, Solfrizzi V, Proitsi P, Adams HH, Allen M, Seripa D, Pastor P, Cupples LA, Price ND, Hannequin D, Frank-García A, Levy D, Chakrabarty P, Caffarra P, Giegling I, Beiser AS, Giedraitis V, Hampel H, Garcia ME, Wang X, Lannfelt L, Mecocci P, Eiriksdottir G, Crane PK, Pasquier F, Boccardi V, Henández I, Barber RC, Scherer M, Tarraga L, Adams PM, Leber M, Chen Y, Albert MS, Riedel-Heller S, Emilsson V, Beekly D, Braae A, Schmidt R, Blacker D, Masullo C, Schmidt H, Doody RS, Spalletta G, Jr WTL, Fairchild TJ, Bossù P, Lopez OL, Frosch MP, Sacchinelli E, Ghetti B, Yang Q, Huebinger RM, Jessen F, Li S, Kamboh MI, Morris J, Sotolongo-Grau O, Katz MJ, Corcoran C, Dunstan M, Braddel A, Thomas C, Meggy A, Marshall R, Gerrish A, Chapman J, Aguilar M, Taylor S, Hill M, Fairén MD, Hodges A, Vellas B, Soininen H, Kloszewska I, Daniilidou M, Uphill J, Patel Y, Hughes JT, Lord J, Turton J, Hartmann AM, Cecchetti R, Fenoglio C, Serpente M, Arcaro M, Caltagirone C, Orfei MD, Ciaramella A, Pichler S, Mayhaus M, Gu W, Lleó A, Fortea J, Blesa R, Barber IS, Brookes K, Cupidi C, Maletta RG, Carrell D, Sorbi S, Moebus S, Urbano M, Pilotto A, Kornhuber J, Bosco P, Todd S, Craig D, Johnston J, Gill M, Lawlor B, Lynch A, Fox NC, Hardy J, Albin RL, Apostolova LG, Arnold SE, Asthana S, Atwood CS, Baldwin CT, Barnes LL, Barral S, Beach TG, Becker JT, Bigio EH, Bird TD, Boeve BF, Bowen JD, Boxer A, Burke JR, Burns JM, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carlsson CM, Carney RM, Carrasquillo MM, Carroll SL, Diaz CC, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, Dick M, Duara R, Evans DA, Faber KM, Fallon KB, Fardo DW, Farlow MR, Ferris S, Foroud TM, Galasko DR, Gearing M, Geschwind DH, Gilbert JR, Graff-Radford NR, Green RC, Growdon JH, Hamilton RL, Harrell LE, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Abner E, Jin LW, Jun G, Karydas A, Kaye JA, Kim R, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lunetta KL, Lyketsos CG, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Morris JC, Murrell JR, Myers AJ, O'Bryant S, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Perry W, Peskind E, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosen HJ, Rosenberg RN, Sager MA, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Swerdlow RH, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Van Eldik LJ, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Wilhelmsen KC, Williamson J, Wingo TS, Woltjer RL, Wright CB, Yu CE, Yu L, Garzia F, Golamaully F, Septier G, Engelborghs S, Vandenberghe R, De Deyn PP, Fernadez CM, Benito YA, Thonberg H, Forsell C, Lilius L, Kinhult-Stählbom A, Kilander L, Brundin R, Concari L, Helisalmi S, Koivisto AM, Haapasalo A, Dermecourt V, Fievet N, Hanon O, Dufouil C, Brice A, Ritchie K, Dubois B, Himali JJ, Keene CD, Tschanz J, Fitzpatrick AL, Kukull WA, Norton M, Aspelund T, Larson EB, Munger R, Rotter JI, Lipton RB, et al. RarView Related Profiles.

Beiser, Alexa
DeStefano, Anita
McKee, Ann
O'Donnell, Christopher
Satizabal, Claudia
Jun, Gyungah
Lin, Honghuang
Himali, Jayandra
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil
Yang, Qiong
Stern, Robert
Choi, Seung Hoan
Seshadri, Sudha

PMID: 28714976; PMCID: PMC5669039; DOI: 10.1038/ng.3916;

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SLR, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. Correction: The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 07; 9(7):1844-1846.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 28696945; PMCID: PMC5559176; DOI: 10.18632/aging.101260;

Murabito JM, Rong J, Lunetta KL, Huan T, Lin H, Zhao Q, Freedman JE, Tanriverdi K, Levy D, Larson MG. Cross-sectional relations of whole-blood miRNA expression levels and hand grip strength in a community sample. Aging Cell. 2017 Aug; 16(4):888-894.View Related Profiles.

Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn
Larson, Martin

PMID: 28597569; PMCID: PMC5506437; DOI: 10.1111/acel.12622;

Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H, Sulem P, Ruth KS, Whalen S, Sarkar AK, Albrecht E, Altmaier E, Amini M, Barbieri CM, Boutin T, Campbell A, Demerath E, Giri A, He C, Hottenga JJ, Karlsson R, Kolcic I, Loh PR, Lunetta KL, Mangino M, Marco B, McMahon G, Medland SE, Nolte IM, Noordam R, Nutile T, Paternoster L, Perjakova N, Porcu E, Rose LM, Schraut KE, Segrè AV, Smith AV, Stolk L, Teumer A, Andrulis IL, Bandinelli S, Beckmann MW, Benitez J, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Brand JS, Brauch H, Brenner H, Broer L, Brüning T, Buring JE, Campbell H, Catamo E, Chanock S, Chenevix-Trench G, Corre T, Couch FJ, Cousminer DL, Cox A, Crisponi L, Czene K, Davey Smith G, de Geus EJCN, de Mutsert R, De Vivo I, Dennis J, Devilee P, Dos-Santos-Silva I, Dunning AM, Eriksson JG, Fasching PA, Fernández-Rhodes L, Ferrucci L, Flesch-Janys D, Franke L, Gabrielson M, Gandin I, Giles GG, Grallert H, Gudbjartsson DF, Guénel P, Hall P, Hallberg E, Hamann U, Harris TB, Hartman CA, Heiss G, Hooning MJ, Hopper JL, Hu F, Hunter DJ, Ikram MA, Im HK, Järvelin MR, Joshi PK, Karasik D, Kellis M, Kutalik Z, LaChance G, Lambrechts D, Langenberg C, Launer LJ, Laven JSE, Lenarduzzi S, Li J, Lind PA, Lindstrom S, Liu Y, Luan J, Mägi R, Mannermaa A, Mbarek H, McCarthy MI, Meisinger C, Meitinger T, Menni C, Metspalu A, Michailidou K, Milani L, Milne RL, Montgomery GW, Mulligan AM, Nalls MA, Navarro P, Nevanlinna H, Nyholt DR, Oldehinkel AJ, O'Mara TA, Padmanabhan S, Palotie A, Pedersen N, Peters A, Peto J, Pharoah PDP, Pouta A, Radice P, Rahman I, Ring SM, Robino A, Rosendaal FR, Rudan I, Rueedi R, Ruggiero D, Sala CF, Schmidt MK, Scott RA, Shah M, Sorice R, Southey MC, Sovio U, Stampfer M, Steri M, Strauch K, Tanaka T, Tikkanen E, Timpson NJ, Traglia M, Truong T, Tyrer JP, Uitterlinden AG, Edwards DRV, Vitart V, Völker U, Vollenweider P, Wang Q, Widen E, van Dijk KW, Willemsen G, Winqvist R, Wolffenbuttel BHR, Zhao JH, Zoledziewska M, Zygmunt M, Alizadeh BZ, Boomsma DI, Ciullo M, Cucca F, Esko T, Franceschini N, Gieger C, Gudnason V, Hayward C, Kraft P, Lawlor DA, Magnusson PKE, Martin NG, Mook-Kanamori DO, Nohr EA, Polasek O, Porteous D, Price AL, Ridker PM, Snieder H, Spector TD, Stöckl D, Toniolo D, Ulivi S, Visser JA, Völzke H, Wareham NJ, Wilson JF, Spurdle AB, Thorsteindottir U, Pollard KS, Easton DF, Tung JY, Chang-Claude J, Hinds D, Murray A, Murabito JM, Stefansson K, Ong KK, Perry JRB. Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nat Genet. 2017 Jun; 49(6):834-841.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 28436984; PMCID: PMC5841952; DOI: 10.1038/ng.3841;

Yao S, Hong CC, Bandera EV, Zhu Q, Liu S, Cheng TD, Zirpoli G, Haddad SA, Lunetta KL, Ruiz-Narvaez EA, McCann SE, Troester MA, Rosenberg L, Palmer JR, Olshan AF, Ambrosone CB. Demographic, lifestyle, and genetic determinants of circulating concentrations of 25-hydroxyvitamin D and vitamin D-binding protein in African American and European American women. Am J Clin Nutr. 2017 Jun; 105(6):1362-1371.View Related Profiles.

Ruiz-Narvaez, Edward
Zirpoli, Gary
Palmer, Julie
Lunetta, Kathryn

PMID: 28424184; PMCID: PMC5445669; DOI: 10.3945/ajcn.116.143248;

Williams LA, Olshan AF, Hong CC, Bandera EV, Rosenberg L, Cheng TD, Lunetta KL, McCann SE, Poole C, Kolonel LN, Palmer JR, Ambrosone CB, Troester MA. Alcohol Intake and Breast Cancer Risk in African American Women from the AMBER Consortium. Cancer Epidemiol Biomarkers Prev. 2017 May; 26(5):787-794.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn

PMID: 28420652; PMCID: PMC5568081; DOI: 10.1158/1055-9965.EPI-16-0792;

Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, Horimoto ARVR, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Nikus K, Orho-Melander M, Hamsten A, Heeringa J, Denny JC, Kriebel J, Darbar D, Newton-Cheh C, Shaffer C, Macfarlane PW, Heilmann-Heimbach S, Almgren P, Huang PL, Sotoodehnia N, Soliman EZ, Uitterlinden AG, Hofman A, Franco OH, Völker U, Jöckel KH, Sinner MF, Lin HJ, Guo X, Dichgans M, Ingelsson E, Kooperberg C, Melander O, Loos RJF, Laurikka J, Conen D, Rosand J, van der Harst P, Lokki ML, Kathiresan S, Pereira A, Jukema JW, Hayward C, Rotter JI, März W, Lehtimäki T, Stricker BH, Chung MK, Felix SB, Gudnason V, Alonso A, Roden DM, Kääb S, Chasman DI, Heckbert SR, Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT. Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation. Nat Genet. 2017 Jun; 49(6):946-952.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Yang, Qiong
Choi, Seung Hoan

PMID: 28416818; PMCID: PMC5585859; DOI: 10.1038/ng.3843;

Mahalingaiah S, Sun F, Cheng JJ, Chow ET, Lunetta KL, Murabito JM. Cardiovascular risk factors among women with self-reported infertility. Fertil Res Pract. 2017; 3:7.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Mahalingaiah, Shruthi

PMID: 28620545; PMCID: PMC5424365; DOI: 10.1186/s40738-017-0034-0;

Feng Y, Rhie SK, Huo D, Ruiz-Narvaez EA, Haddad SA, Ambrosone CB, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Press MF, Deming SL, Rodriguez-Gil JL, Zheng Y, Yao S, Han YJ, Ogundiran TO, Rebbeck TR, Adebamowo C, Ojengbede O, Falusi AG, Hennis A, Nemesure B, Ambs S, Blot W, Cai Q, Signorello L, Nathanson KL, Lunetta KL, Sucheston-Campbell LE, Bensen JT, Chanock SJ, Marchand LL, Olshan AF, Kolonel LN, Conti DV, Coetzee GA, Stram DO, Olopade OI, Palmer JR, Haiman CA. Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry. Cancer Epidemiol Biomarkers Prev. 2017 Jul; 26(7):1016-1026.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 28377418; PMCID: PMC5500414; DOI: 10.1158/1055-9965.EPI-16-0567;

Haddad SA, Palmer JR, Lunetta KL, Ng MC, Ruiz-Narváez EA. A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women. PLoS One. 2017; 12(3):e0172577.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 28253288; PMCID: PMC5333820; DOI: 10.1371/journal.pone.0172577;

Murphy ME, Liu S, Yao S, Huo D, Liu Q, Dolfi SC, Hirshfield KM, Hong CC, Hu Q, Olshan AF, Ogundiran TO, Adebamowo C, Domchek SM, Nathanson KL, Nemesure B, Ambs S, Blot WJ, Feng Y, John EM, Bernstein L, Zheng W, Hu JJ, Ziegler RG, Nyante S, Ingles SA, Press MF, Deming SL, Rodriguez-Gil JL, Haiman CA, Olopade OI, Lunetta KL, Palmer JR, Ambrosone CB. A functionally significant SNP in TP53 and breast cancer risk in African-American women. NPJ Breast Cancer. 2017; 3:5.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn

PMID: 28649645; PMCID: PMC5445618; DOI: 10.1038/s41523-017-0007-9;

Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, Foroud TM, Friedland RP, Goate AM, Graff-Radford NR, Hendrie H, Hall KS, Hamilton-Nelson KL, Inzelberg R, Kamboh MI, Kauwe JSK, Kukull WA, Kunkle BW, Kuwano R, Larson EB, Logue MW, Manly JJ, Martin ER, Montine TJ, Mukherjee S, Naj A, Reiman EM, Reitz C, Sherva R, St George-Hyslop PH, Thornton T, Younkin SG, Vardarajan BN, Wang LS, Wendlund JR, Winslow AR, Haines J, Mayeux R, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimers Dement. 2017 Jul; 13(7):727-738.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Sherva, Richard

PMID: 28183528; PMCID: PMC5496797; DOI: 10.1016/j.jalz.2016.12.012;

Choi SH, Labadorf AT, Myers RH, Lunetta KL, Dupuis J, DeStefano AL. Evaluation of logistic regression models and effect of covariates for case-control study in RNA-Seq analysis. BMC Bioinformatics. 2017 Feb 06; 18(1):91.View Related Profiles.

Labadorf, Adam
DeStefano, Anita
Dupuis, Josee
Lunetta, Kathryn
Myers, Richard
Choi, Seung Hoan

PMID: 28166718; PMCID: PMC5294900; DOI: 10.1186/s12859-017-1498-y;

Ben-Avraham D, Karasik D, Verghese J, Lunetta KL, Smith JA, Eicher JD, Vered R, Deelen J, Arnold AM, Buchman AS, Tanaka T, Faul JD, Nethander M, Fornage M, Adams HH, Matteini AM, Callisaya ML, Smith AV, Yu L, De Jager PL, Evans DA, Gudnason V, Hofman A, Pattie A, Corley J, Launer LJ, Knopman DS, Parimi N, Turner ST, Bandinelli S, Beekman M, Gutman D, Sharvit L, Mooijaart SP, Liewald DC, Houwing-Duistermaat JJ, Ohlsson C, Moed M, Verlinden VJ, Mellström D, van der Geest JN, Karlsson M, Hernandez D, McWhirter R, Liu Y, Thomson R, Tranah GJ, Uitterlinden AG, Weir DR, Zhao W, Starr JM, Johnson AD, Ikram MA, Bennett DA, Cummings SR, Deary IJ, Harris TB, Kardia SL, Mosley TH, Srikanth VK, Windham BG, Newman AB, Walston JD, Davies G, Evans DS, Slagboom EP, Ferrucci L, Kiel DP, Murabito JM, Atzmon G. The complex genetics of gait speed: genome-wide meta-analysis approach. Aging (Albany NY). 2017 Jan 10; 9(1):209-246.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 28077804; PMCID: PMC5310665; DOI: 10.18632/aging.101151;

Lin H, Yin X, Xie Z, Lunetta KL, Lubitz SA, Larson MG, Ko D, Magnani JW, Mendelson MM, Liu C, McManus DD, Levy D, Ellinor PT, Benjamin EJ. Methylome-wide Association Study of Atrial Fibrillation in Framingham Heart Study. Sci Rep. 2017 01 09; 7:40377.View Related Profiles.

Liu, Chunyu
Ko, Darae
Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Larson, Martin

PMID: 28067321; PMCID: PMC5220313; DOI: 10.1038/srep40377;

Zhang X, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JI, Schellenberg GD, Pericak-Vance M, Lunetta KL, Farrer LA. NOVEL GENETIC VARIANTS ASSOCIATED WITH FAMILIAL LATE-ONSET ALZHEIMER DISEASE IN THE ALZHEIMER’S DISEASE SEQUENCING PROJECT. Alzheimer's and Dementia. 2017; 13(7):P572. View Publication
Chung J, Wang X, Ma YY, Maruyama T, Kim M, Zhang X, Takeyama H, Mez J, Sherva R, Lunetta KL, Farrer LA, Jun GR. GENOME-WIDE ASSOCIATION STUDY OF ALZHEIMER DISEASE ENDOPHENOTYPES AT PRECLINICAL AND MCI STAGES. Alzheimer's and Dementia. 2017; 13(7):P337-P338. View Publication
Chung J, Ma YY, Zhang X, Yang Q, Beecham G, Lunetta KL, Mez J, Haines JI, Pericak-Vance M, Schellenberg GD, Hun GR, Farrer LA. BIVARIATE GENOME-WIDE ASSOCIATION STUDY OF NEUROPATHOLOGIC FEATURES OF ALZHEIMER’S DISEASE. Alzheimer's and Dementia. 2017; 13(7):P217. View Publication

Chatterjee NA, Giulianini F, Geelhoed B, Lunetta KL, Misialek JR, Niemeijer MN, Rienstra M, Rose LM, Smith AV, Arking DE, Ellinor PT, Heeringa J, Lin H, Lubitz SA, Soliman EZ, Verweij N, Alonso A, Benjamin EJ, Gudnason V, Stricker BH, Van Der Harst P, Chasman DI, Albert CM. Genetic Obesity and the Risk of Atrial Fibrillation: Causal Estimates from Mendelian Randomization. Circulation. 2017 Feb 21; 135(8):741-754.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn

PMID: 27974350; PMCID: PMC5322057; DOI: 10.1161/CIRCULATIONAHA.116.024921;

Zhu Q, Shepherd L, Lunetta KL, Yao S, Liu Q, Hu Q, Haddad SA, Sucheston-Campbell L, Bensen JT, Bandera EV, Rosenberg L, Liu S, Haiman CA, Olshan AF, Palmer JR, Ambrosone CB. Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach. Oncotarget. 2016 Dec 13; 7(50):83160-83176.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn

PMID: 27825120; PMCID: PMC5341253; DOI: 10.18632/oncotarget.13075;

Direk N, Williams S, Smith JA, Ripke S, Air T, Amare AT, Amin N, Baune BT, Bennett DA, Blackwood DHR, Boomsma D, Breen G, Buttenschøn HN, Byrne EM, Børglum AD, Castelao E, Cichon S, Clarke TK, Cornelis MC, Dannlowski U, De Jager PL, Demirkan A, Domenici E, van Duijn CM, Dunn EC, Eriksson JG, Esko T, Faul JD, Ferrucci L, Fornage M, de Geus E, Gill M, Gordon SD, Grabe HJ, van Grootheest G, Hamilton SP, Hartman CA, Heath AC, Hek K, Hofman A, Homuth G, Horn C, Jan Hottenga J, Kardia SLR, Kloiber S, Koenen K, Kutalik Z, Ladwig KH, Lahti J, Levinson DF, Lewis CM, Lewis G, Li QS, Llewellyn DJ, Lucae S, Lunetta KL, MacIntyre DJ, Madden P, Martin NG, McIntosh AM, Metspalu A, Milaneschi Y, Montgomery GW, Mors O, Mosley TH, Murabito JM, Müller-Myhsok B, Nöthen MM, Nyholt DR, O'Donovan MC, Penninx BW, Pergadia ML, Perlis R, Potash JB, Preisig M, Purcell SM, Quiroz JA, Räikkönen K, Rice JP, Rietschel M, Rivera M, Schulze TG, Shi J, Shyn S, Sinnamon GC, Smit JH, Smoller JW, Snieder H, Tanaka T, Tansey KE, Teumer A, Uher R, Umbricht D, Van der Auwera S, Ware EB, Weir DR, Weissman MM, Willemsen G, Yang J, Zhao W, Tiemeier H, Sullivan PF. An Analysis of Two Genome-wide Association Meta-analyses Identifies a New Locus for Broad Depression Phenotype. Biol Psychiatry. 2017 Sep 01; 82(5):322-329.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 28049566; PMCID: PMC5462867; DOI: 10.1016/j.biopsych.2016.11.013;

Lin H, Mueller-Nurasyid M, Smith AV, Arking DE, Barnard J, Bartz TM, Lunetta KL, Lohman K, Kleber ME, Lubitz SA, Geelhoed B, Trompet S, Niemeijer MN, Kacprowski T, Chasman DI, Klarin D, Sinner MF, Waldenberger M, Meitinger T, Harris TB, Launer LJ, Soliman EZ, Chen LY, Smith JD, Van Wagoner DR, Rotter JI, Psaty BM, Xie Z, Hendricks AE, Ding J, Delgado GE, Verweij N, van der Harst P, Macfarlane PW, Ford I, Hofman A, Uitterlinden A, Heeringa J, Franco OH, Kors JA, Weiss S, Völzke H, Rose LM, Natarajan P, Kathiresan S, Kääb S, Gudnason V, Alonso A, Chung MK, Heckbert SR, Benjamin EJ, Liu Y, März W, Rienstra M, Jukema JW, Stricker BH, Dörr M, Albert CM, Ellinor PT. Gene-gene Interaction Analyses for Atrial Fibrillation. Sci Rep. 2016 11 08; 6:35371.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn

PMID: 27824142; PMCID: PMC5099695; DOI: 10.1038/srep35371;

Huo D, Feng Y, Haddad S, Zheng Y, Yao S, Han YJ, Ogundiran TO, Adebamowo C, Ojengbede O, Falusi AG, Zheng W, Blot W, Cai Q, Signorello L, John EM, Bernstein L, Hu JJ, Ziegler RG, Nyante S, Bandera EV, Ingles SA, Press MF, Deming SL, Rodriguez-Gil JL, Nathanson KL, Domchek SM, Rebbeck TR, Ruiz-Narváez EA, Sucheston-Campbell LE, Bensen JT, Simon MS, Hennis A, Nemesure B, Leske MC, Ambs S, Chen LS, Qian F, Gamazon ER, Lunetta KL, Cox NJ, Chanock SJ, Kolonel LN, Olshan AF, Ambrosone CB, Olopade OI, Palmer JR, Haiman CA. Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancer. Hum Mol Genet. 2016 11 01; 25(21):4835-4846.View Related Profiles.

Ruiz-Narvaez, Edward
Qian, Frank
Palmer, Julie
Lunetta, Kathryn

PMID: 28171663; PMCID: PMC5975608; DOI: 10.1093/hmg/ddw305;

Lubitz SA, Yin X, Lin HJ, Kolek M, Smith JG, Trompet S, Rienstra M, Rost NS, Teixeira PL, Almgren P, Anderson CD, Chen LY, Engström G, Ford I, Furie KL, Guo X, Larson MG, Lunetta KL, Macfarlane PW, Psaty BM, Soliman EZ, Sotoodehnia N, Stott DJ, Taylor KD, Weng LC, Yao J, Geelhoed B, Verweij N, Siland JE, Kathiresan S, Roselli C, Roden DM, van der Harst P, Darbar D, Jukema JW, Melander O, Rosand J, Rotter JI, Heckbert SR, Ellinor PT, Alonso A, Benjamin EJ. Genetic Risk Prediction of Atrial Fibrillation. Circulation. 2017 Apr 04; 135(14):1311-1320.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Larson, Martin

PMID: 27793994; PMCID: PMC5380586; DOI: 10.1161/CIRCULATIONAHA.116.024143;

Ruiz-Narváez EA, Lunetta KL, Hong CC, Haddad S, Yao S, Cheng TD, Bensen JT, Bandera EV, Haiman CA, Troester MA, Ambrosone CB, Rosenberg L, Palmer JR. Genetic variation in the insulin, insulin-like growth factor, growth hormone, and leptin pathways in relation to breast cancer in African-American women: the AMBER consortium. NPJ Breast Cancer. 2016; 2.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 27942580; PMCID: PMC5142758; DOI: 10.1038/npjbcancer.2016.34;

Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, Foroud T, Goate A, Graff-Radford NR, Hall KS, Kamboh MI, Kukull WA, Larson EB, Manly JJ, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LA. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimers Dement. 2017 Feb; 13(2):119-129.View Related Profiles.

Jun, Gyungah
Chung, Jaeyoon
Mez, Jesse
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Sherva, Richard

PMID: 27770636; PMCID: PMC5318231; DOI: 10.1016/j.jalz.2016.09.002;

Lent S, Deng X, Cupples LA, Lunetta KL, Liu CT, Zhou Y. Imputing rare variants in families using a two-stage approach. BMC Proc. 2016; 10(Suppl 7):209-214.View Related Profiles.

Lunetta, Kathryn
Cupples, L

PMID: 27980638; PMCID: PMC5133481; DOI: 10.1186/s12919-016-0032-y;

Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, Tanaka T, Kiel DP, Liang L, Vokonas P, Schwartz J, Lunetta KL, Murabito JM, Bandinelli S, Hernandez DG, Melzer D, Nalls M, Pilling LC, Price TR, Singleton AB, Gieger C, Holle R, Kretschmer A, Kronenberg F, Kunze S, Linseisen J, Meisinger C, Rathmann W, Waldenberger M, Visscher PM, Shah S, Wray NR, McRae AF, Franco OH, Hofman A, Uitterlinden AG, Absher D, Assimes T, Levine ME, Lu AT, Tsao PS, Hou L, Manson JE, Carty CL, LaCroix AZ, Reiner AP, Spector TD, Feinberg AP, Levy D, Baccarelli A, van Meurs J, Bell JT, Peters A, Deary IJ, Pankow JS, Ferrucci L, Horvath S. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging (Albany NY). 2016 Sep 28; 8(9):1844-1865.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Vokonas, Pantel

PMID: 27690265; PMCID: PMC5076441; DOI: 10.18632/aging.101020;

Ruiz-Narváez EA, Sucheston-Campbell L, Bensen JT, Yao S, Haddad S, Haiman CA, Bandera EV, John EM, Bernstein L, Hu JJ, Ziegler RG, Deming SL, Olshan AF, Ambrosone CB, Palmer JR, Lunetta KL. Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor Subtypes. Front Genet. 2016; 7:170.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 27708667; PMCID: PMC5030764; DOI: 10.3389/fgene.2016.00170;

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 27594435

Lubitz SA, Brody JA, Bihlmeyer NA, Roselli C, Weng LC, Christophersen IE, Alonso A, Boerwinkle E, Gibbs RA, Bis JC, Cupples LA, Mohler PJ, Nickerson DA, Muzny D, Perez MV, Psaty BM, Soliman EZ, Sotoodehnia N, Lunetta KL, Benjamin EJ, Heckbert SR, Arking DE, Ellinor PT, Lin H. Whole Exome Sequencing in Atrial Fibrillation. PLoS Genet. 2016 Sep; 12(9):e1006284.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Lunetta, Kathryn
Cupples, L

PMID: 27589061; PMCID: PMC5010214; DOI: 10.1371/journal.pgen.1006284;

Zhuang WV, Murabito JM, Lunetta KL. Phenotypically Enriched Genotypic Imputation in Genetic Association Tests. Hum Hered. 2016; 81(1):35-45.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 27576319

Zhang J, Yao S, Hu Q, Zhu Q, Liu S, Lunetta KL, Haddad SA, Yang N, Shen H, Hong CC, Sucheston-Campbell L, Ruiz-Narvaez EA, Bensen JT, Troester MA, Bandera EV, Rosenberg L, Haiman CA, Olshan AF, Palmer JR, Ambrosone CB. Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER Consortium. Carcinogenesis. 2016 Oct; 37(10):951-956.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 27485598; PMCID: PMC5035397; DOI: 10.1093/carcin/bgw077;

Matteini AM, Tanaka T, Karasik D, Atzmon G, Chou WC, Eicher JD, Johnson AD, Arnold AM, Callisaya ML, Davies G, Evans DS, Holtfreter B, Lohman K, Lunetta KL, Mangino M, Smith AV, Smith JA, Teumer A, Yu L, Arking DE, Buchman AS, Chibinik LB, De Jager PL, Evans DA, Faul JD, Garcia ME, Gillham-Nasenya I, Gudnason V, Hofman A, Hsu YH, Ittermann T, Lahousse L, Liewald DC, Liu Y, Lopez L, Rivadeneira F, Rotter JI, Siggeirsdottir K, Starr JM, Thomson R, Tranah GJ, Uitterlinden AG, Völker U, Völzke H, Weir DR, Yaffe K, Zhao W, Zhuang WV, Zmuda JM, Bennett DA, Cummings SR, Deary IJ, Ferrucci L, Harris TB, Kardia SL, Kocher T, Kritchevsky SB, Psaty BM, Seshadri S, Spector TD, Srikanth VK, Windham BG, Zillikens MC, Newman AB, Walston JD, Kiel DP, Murabito JM. GWAS analysis of handgrip and lower body strength in older adults in the CHARGE consortium. Aging Cell. 2016 Oct; 15(5):792-800.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Seshadri, Sudha

PMID: 27325353; PMCID: PMC5013019; DOI: 10.1111/acel.12468;

Haddad SA, Ruiz-Narváez EA, Haiman CA, Sucheston-Campbell LE, Bensen JT, Zhu Q, Liu S, Yao S, Bandera EV, Rosenberg L, Olshan AF, Ambrosone CB, Palmer JR, Lunetta KL. An exome-wide analysis of low frequency and rare variants in relation to risk of breast cancer in African American Women: the AMBER Consortium. Carcinogenesis. 2016 Sep; 37(9):870-877.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 27267999; PMCID: PMC5008246; DOI: 10.1093/carcin/bgw067;

McCabe EL, Larson MG, Lunetta KL, Newman AB, Cheng S, Murabito JM. Association of an Index of Healthy Aging With Incident Cardiovascular Disease and Mortality in a Community-Based Sample of Older Adults. J Gerontol A Biol Sci Med Sci. 2016 Dec; 71(12):1695-1701.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Larson, Martin

PMID: 27117172; PMCID: PMC5106860; DOI: 10.1093/gerona/glw077;

Hong J, Lunetta KL, Cupples LA, Dupuis J, Liu CT. Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies. Genet Epidemiol. 2016 May; 40(4):284-92.View Related Profiles.

Liu, Ching-Ti
Dupuis, Josee
Lunetta, Kathryn
Cupples, L

PMID: 27061095; PMCID: PMC4833581; DOI: 10.1002/gepi.21963;

Demirkan A, Lahti J, Direk N, Viktorin A, Lunetta KL, Terracciano A, Nalls MA, Tanaka T, Hek K, Fornage M, Wellmann J, Cornelis MC, Ollila HM, Yu L, Smith JA, Pilling LC, Isaacs A, Palotie A, Zhuang WV, Zonderman A, Faul JD, Sutin A, Meirelles O, Mulas A, Hofman A, Uitterlinden A, Rivadeneira F, Perola M, Zhao W, Salomaa V, Yaffe K, Luik AI, Liu Y, Ding J, Lichtenstein P, Landén M, Widen E, Weir DR, Llewellyn DJ, Murray A, Kardia SL, Eriksson JG, Koenen K, Magnusson PK, Ferrucci L, Mosley TH, Cucca F, Oostra BA, Bennett DA, Paunio T, Berger K, Harris TB, Pedersen NL, Murabito JM, Tiemeier H, van Duijn CM, Räikkönen K. Somatic, positive and negative domains of the Center for Epidemiological Studies Depression (CES-D) scale: a meta-analysis of genome-wide association studies. Psychol Med. 2016 Jun; 46(8):1613-23.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 26997408; PMCID: PMC5812462; DOI: 10.1017/S0033291715002081;

Pilling LC, Atkins JL, Bowman K, Jones SE, Tyrrell J, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Wood AR, Freathy RM, Murray A, Weedon MN, Xue L, Lunetta K, Murabito JM, Harries LW, Robine JM, Brayne C, Kuchel GA, Ferrucci L, Frayling TM, Melzer D. Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants. Aging (Albany NY). 2016 Mar; 8(3):547-60.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 27015805; PMCID: PMC4833145; DOI: 10.18632/aging.100930;

Ruiz-Narváez EA, Haddad SA, Lunetta KL, Yao S, Bensen JT, Sucheston-Campbell LE, Hong CC, Haiman CA, Olshan AF, Ambrosone CB, Palmer JR. Gene-based analysis of the fibroblast growth factor receptor signaling pathway in relation to breast cancer in African American women: the AMBER consortium. Breast Cancer Res Treat. 2016 Jan; 155(2):355-63.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 26743380; PMCID: PMC4890604; DOI: 10.1007/s10549-015-3672-0;

Bethea TN, Rosenberg L, Castro-Webb N, Lunetta KL, Sucheston-Campbell LE, Ruiz-Narváez EA, Charlot M, Park SY, Bandera EV, Troester MA, Ambrosone CB, Palmer JR. Family History of Cancer in Relation to Breast Cancer Subtypes in African American Women. Cancer Epidemiol Biomarkers Prev. 2016 Feb; 25(2):366-73.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn
Rosenberg, Lynn
Charlot, Marjory
Bethea, Traci

PMID: 26721669; PMCID: PMC4767636; DOI: 10.1158/1055-9965.EPI-15-1068;

Yao S, Haddad SA, Hu Q, Liu S, Lunetta KL, Ruiz-Narvaez EA, Hong CC, Zhu Q, Sucheston-Campbell L, Cheng TY, Bensen JT, Johnson CS, Trump DL, Haiman CA, Olshan AF, Palmer JR, Ambrosone CB. Genetic variations in vitamin D-related pathways and breast cancer risk in African American women in the AMBER consortium. Int J Cancer. 2016 May 1; 138(9):2118-26.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn

PMID: 26650177; PMCID: PMC5087916; DOI: 10.1002/ijc.29954;

Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, Schick UM, Stolk L, Teumer A, Thompson DJ, Traglia M, Wang CA, Yerges-Armstrong LM, Antoniou AC, Barbieri C, Coviello AD, Cucca F, Demerath EW, Dunning AM, Gandin I, Grove ML, Gudbjartsson DF, Hocking LJ, Hofman A, Huang J, Jackson RD, Karasik D, Kriebel J, Lange EM, Lange LA, Langenberg C, Li X, Luan J, Mägi R, Morrison AC, Padmanabhan S, Pirie A, Polasek O, Porteous D, Reiner AP, Rivadeneira F, Rudan I, Sala CF, Schlessinger D, Scott RA, Stöckl D, Visser JA, Völker U, Vozzi D, Wilson JG, Zygmunt M, Boerwinkle E, Buring JE, Crisponi L, Easton DF, Hayward C, Hu FB, Liu S, Metspalu A, Pennell CE, Ridker PM, Strauch K, Streeten EA, Toniolo D, Uitterlinden AG, Ulivi S, Völzke H, Wareham NJ, Wellons M, Franceschini N, Chasman DI, Thorsteinsdottir U, Murray A, Stefansson K, Murabito JM, Ong KK, Perry JR. Corrigendum: Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015; 6:10257.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 26674845; PMCID: PMC4703878; DOI: 10.1038/ncomms10257;

Cheng TY, Ambrosone CB, Hong CC, Lunetta KL, Liu S, Hu Q, Yao S, Sucheston-Campbell L, Bandera EV, Ruiz-Narváez EA, Haddad S, Troester MA, Haiman CA, Bensen JT, Olshan AF, Palmer JR, Rosenberg L. Genetic variants in the mTOR pathway and breast cancer risk in African American women. Carcinogenesis. 2016 Jan; 37(1):49-55.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn
Rosenberg, Lynn

PMID: 26577839; PMCID: PMC5006112; DOI: 10.1093/carcin/bgv160;

Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith PA, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Lee JH, Schellenberg GD, St George-Hyslop P, Mayeux R, Rogaeva E. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. JAMA Neurol. 2015 Nov; 72(11):1313-23.View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark

PMID: 26366463; PMCID: PMC4641052; DOI: 10.1001/jamaneurol.2015.1700;

Pilling LC, Joehanes R, Kacprowski T, Peters M, Jansen R, Karasik D, Kiel DP, Harries LW, Teumer A, Powell J, Levy D, Lin H, Lunetta K, Munson P, Bandinelli S, Henley W, Hernandez D, Singleton A, Tanaka T, van Grootheest G, Hofman A, Uitterlinden AG, Biffar R, Gläser S, Homuth G, Malsch C, Völker U, Penninx B, van Meurs JB, Ferrucci L, Kocher T, Murabito J, Melzer D. Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons. Physiol Genomics. 2016 Jan; 48(1):1-11.View Related Profiles.

Lin, Honghuang
Murabito, Joanne
Lunetta, Kathryn

PMID: 26487704; PMCID: PMC4757025; DOI: 10.1152/physiolgenomics.00054.2015;

Haddad SA, Lunetta KL, Ruiz-Narváez EA, Bensen JT, Hong CC, Sucheston-Campbell LE, Yao S, Bandera EV, Rosenberg L, Haiman CA, Troester MA, Ambrosone CB, Palmer JR. Hormone-related pathways and risk of breast cancer subtypes in African American women. Breast Cancer Res Treat. 2015 Nov; 154(1):145-54.View Related Profiles.

Ruiz-Narvaez, Edward
Palmer, Julie
Lunetta, Kathryn
Rosenberg, Lynn

PMID: 26458823; PMCID: PMC5082744; DOI: 10.1007/s10549-015-3594-x;

Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM, Schick UM, Smith JA, Teumer A, Traglia M, Vuckovic D, Yao J, Zhao W, Albrecht E, Amin N, Corre T, Hottenga JJ, Mangino M, Smith AV, Tanaka T, Abecasis GR, Andrulis IL, Anton-Culver H, Antoniou AC, Arndt V, Arnold AM, Barbieri C, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bernstein L, Bielinski SJ, Blomqvist C, Boerwinkle E, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Boutin TS, Brauch H, Brenner H, Brüning T, Burwinkel B, Campbell A, Campbell H, Chanock SJ, Chapman JR, Chen YD, Chenevix-Trench G, Couch FJ, Coviello AD, Cox A, Czene K, Darabi H, De Vivo I, Demerath EW, Dennis J, Devilee P, Dörk T, Dos-Santos-Silva I, Dunning AM, Eicher JD, Fasching PA, Faul JD, Figueroa J, Flesch-Janys D, Gandin I, Garcia ME, García-Closas M, Giles GG, Girotto GG, Goldberg MS, González-Neira A, Goodarzi MO, Grove ML, Gudbjartsson DF, Guénel P, Guo X, Haiman CA, Hall P, Hamann U, Henderson BE, Hocking LJ, Hofman A, Homuth G, Hooning MJ, Hopper JL, Hu FB, Huang J, Humphreys K, Hunter DJ, Jakubowska A, Jones SE, Kabisch M, Karasik D, Knight JA, Kolcic I, Kooperberg C, Kosma VM, Kriebel J, Kristensen V, Lambrechts D, Langenberg C, Li J, Li X, Lindström S, Liu Y, Luan J, Lubinski J, Mägi R, Mannermaa A, Manz J, Margolin S, Marten J, Martin NG, Masciullo C, Meindl A, Michailidou K, Mihailov E, Milani L, Milne RL, Müller-Nurasyid M, Nalls M, Neale BM, Nevanlinna H, Neven P, Newman AB, Nordestgaard BG, Olson JE, Padmanabhan S, Peterlongo P, Peters U, Petersmann A, Peto J, Pharoah PD, Pirastu NN, Pirie A, Pistis G, Polasek O, Porteous D, Psaty BM, Pylkäs K, Radice P, Raffel LJ, Rivadeneira F, Rudan I, Rudolph A, Ruggiero D, Sala CF, Sanna S, Sawyer EJ, Schlessinger D, Schmidt MK, Schmidt F, Schmutzler RK, Schoemaker MJ, Scott RA, Seynaeve CM, Simard J, Sorice R, Southey MC, Stöckl D, Strauch K, Swerdlow A, Taylor KD, Thorsteinsdottir U, Toland AE, Tomlinson I, Truong T, Tryggvadottir L, Turner ST, Vozzi D, Wang Q, Wellons M, Willemsen G, Wilson JF, Winqvist R, Wolffenbuttel BB, Wright AF, Yannoukakos D, Zemunik T, Zheng W, Zygmunt M, Bergmann S, Boomsma DI, Buring JE, Ferrucci L, Montgomery GW, Gudnason V, Spector TD, van Duijn CM, Alizadeh BZ, Ciullo M, Crisponi L, Easton DF, Gasparini PP, Gieger C, Harris TB, Hayward C, Kardia SL, Kraft P, McKnight B, Metspalu A, Morrison AC, Reiner AP, Ridker PM, Rotter JI, Toniolo D, Uitterlinden AG, Ulivi S, Völzke H, Wareham NJ, Weir DR, Yerges-Armstrong LM, Price AL, Stefansson K, Visser JA, Ong KK, Chang-Claude J, Murabito JM, Perry JR, Murray A. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015 Nov; 47(11):1294-303.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 26414677; PMCID: PMC4661791; DOI: 10.1038/ng.3412;

Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, Schick UM, Stolk L, Teumer A, Thompson DJ, Traglia M, Wang CA, Yerges-Armstrong LM, Antoniou AC, Barbieri C, Coviello AD, Cucca F, Demerath EW, Dunning AM, Gandin I, Grove ML, Gudbjartsson DF, Hocking LJ, Hofman A, Huang J, Jackson RD, Karasik D, Kriebel J, Lange EM, Lange LA, Langenberg C, Li X, Luan J, Mägi R, Morrison AC, Padmanabhan S, Pirie A, Polasek O, Porteous D, Reiner AP, Rivadeneira F, Rudan I, Sala CF, Schlessinger D, Scott RA, Stöckl D, Visser JA, Völker U, Vozzi D, Wilson JG, Zygmunt M, Boerwinkle E, Buring JE, Crisponi L, Easton DF, Hayward C, Hu FB, Liu S, Metspalu A, Pennell CE, Ridker PM, Strauch K, Streeten EA, Toniolo D, Uitterlinden AG, Ulivi S, Völzke H, Wareham NJ, Wellons M, Franceschini N, Chasman DI, Thorsteinsdottir U, Murray A, Stefansson K, Murabito JM, Ong KK, Perry JR. Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015; 6:7756.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 26239645; PMCID: PMC4538850; DOI: 10.1038/ncomms8756;

Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H, Mitchell M, Hernandez D, Ying SX, Lunetta KL, Benjamin EJ, Singleton A, Levy D, Munson P, Murabito JM, Ferrucci L. Gene expression markers of age-related inflammation in two human cohorts. Exp Gerontol. 2015 Oct; 70:37-45.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Murabito, Joanne
Dupuis, Josee
Lunetta, Kathryn

PMID: 26087330; PMCID: PMC4600657; DOI: 10.1016/j.exger.2015.05.012;

Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue MW, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hardy J, Hendrie HC, Hall KS, Goate AM, Lang R, Byrd GS, Kukull WA, Foroud TM, Farrer LA, Martin ER, Pericak-Vance MA, Schellenberg GD, Mayeux R, Haines JL, Thornton-Wells TA. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimers Dement. 2016 Mar; 12(3):233-43.View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark

PMID: 26092349; PMCID: PMC4681680; DOI: 10.1016/j.jalz.2015.02.012;

Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, Beecham GW, Smith AV, Chouraki V, Hamilton-Nelson KL, Ikram MA, Fievet N, Denning N, Martin ER, Schmidt H, Kamatani Y, Dunstan ML, Valladares O, Laza AR, Zelenika D, Ramirez A, Foroud TM, Choi SH, Boland A, Becker T, Kukull WA, van der Lee SJ, Pasquier F, Cruchaga C, Beekly D, Fitzpatrick AL, Hanon O, Gill M, Barber R, Gudnason V, Campion D, Love S, Bennett DA, Amin N, Berr C, Tsolaki M, Buxbaum JD, Lopez OL, Deramecourt V, Fox NC, Cantwell LB, Tárraga L, Dufouil C, Hardy J, Crane PK, Eiriksdottir G, Hannequin D, Clarke R, Evans D, Mosley TH, Letenneur L, Brayne C, Maier W, De Jager P, Emilsson V, Dartigues JF, Hampel H, Kamboh MI, de Bruijn RF, Tzourio C, Pastor P, Larson EB, Rotter JI, O'Donovan MC, Montine TJ, Nalls MA, Mead S, Reiman EM, Jonsson PV, Holmes C, St George-Hyslop PH, Boada M, Passmore P, Wendland JR, Schmidt R, Morgan K, Winslow AR, Powell JF, Carasquillo M, Younkin SG, Jakobsdóttir J, Kauwe JS, Wilhelmsen KC, Rujescu D, Nöthen MM, Hofman A, Jones L, Haines JL, Psaty BM, Van Broeckhoven C, Holmans P, Launer LJ, Mayeux R, Lathrop M, Goate AM, Escott-Price V, Seshadri S, Pericak-Vance MA, Amouyel P, Williams J, van Duijn CM, Schellenberg GD, Farrer LA. A novel Alzheimer disease locus located near the gene encoding tau protein. Mol Psychiatry. 2016 Jan; 21(1):108-17.View Related Profiles.

DeStefano, Anita
Jun, Gyungah
Chung, Jaeyoon
Lunetta, Kathryn
Farrer, Lindsay
Choi, Seung Hoan
Seshadri, Sudha

PMID: 25778476; PMCID: PMC4573764; DOI: 10.1038/mp.2015.23;

Minster RL, Sanders JL, Singh J, Kammerer CM, Barmada MM, Matteini AM, Zhang Q, Wojczynski MK, Daw EW, Brody JA, Arnold AM, Lunetta KL, Murabito JM, Christensen K, Perls TT, Province MA, Newman AB. Genome-Wide Association Study and Linkage Analysis of the Healthy Aging Index. J Gerontol A Biol Sci Med Sci. 2015 Aug; 70(8):1003-8.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn
Perls, Thomas

PMID: 25758594; PMCID: PMC4506316; DOI: 10.1093/gerona/glv006;

Bethea TN, Rosenberg L, Hong CC, Troester MA, Lunetta KL, Bandera EV, Schedin P, Kolonel LN, Olshan AF, Ambrosone CB, Palmer JR. A case-control analysis of oral contraceptive use and breast cancer subtypes in the African American Breast Cancer Epidemiology and Risk Consortium. Breast Cancer Res. 2015; 17:22.View Related Profiles.

Palmer, Julie
Lunetta, Kathryn
Rosenberg, Lynn
Bethea, Traci

PMID: 25849024; PMCID: PMC4358874; DOI: 10.1186/s13058-015-0535-x;

Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta KL, Farrer LA, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, McDonald BC, Farlow MR, Ghetti B, Huentelman MJ, Saykin AJ. Protective variant for hippocampal atrophy identified by whole exome sequencing. Ann Neurol. 2015 Mar; 77(3):547-52.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay

PMID: 25559091; PMCID: PMC4387567; DOI: 10.1002/ana.24349;

Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E; Alzheimer's Disease Genetics Consortium, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD; National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States. JAMA Neurol. 2015; 72(2):209-216.

Marioni RE, Shah S, McRae AF, Chen BH, Colicino E, Harris SE, Gibson J, Henders AK, Redmond P, Cox SR, Pattie A, Corley J, Murphy L, Martin NG, Montgomery GW, Feinberg AP, Fallin MD, Multhaup ML, Jaffe AE, Joehanes R, Schwartz J, Just AC, Lunetta KL, Murabito JM, Starr JM, Horvath S, Baccarelli AA, Levy D, Visscher PM, Wray NR, Deary IJ. DNA methylation age of blood predicts all-cause mortality in later life. Genome Biol. 2015; 16:25.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 25633388; PMCID: PMC4350614; DOI: 10.1186/s13059-015-0584-6;

Bihlmeyer NA, Brody JA, Smith AV, Lunetta KL, Nalls M, Smith JA, Tanaka T, Davies G, Yu L, Mirza SS, Teumer A, Coresh J, Pankow JS, Franceschini N, Scaria A, Oshima J, Psaty BM, Gudnason V, Eiriksdottir G, Harris TB, Li H, Karasik D, Kiel DP, Garcia M, Liu Y, Faul JD, Kardia SL, Zhao W, Ferrucci L, Allerhand M, Liewald DC, Redmond P, Starr JM, De Jager PL, Evans DA, Direk N, Ikram MA, Uitterlinden A, Homuth G, Lorbeer R, Grabe HJ, Launer L, Murabito JM, Singleton AB, Weir DR, Bandinelli S, Deary IJ, Bennett DA, Tiemeier H, Kocher T, Lumley T, Arking DE. Genetic diversity is a predictor of mortality in humans. BMC Genet. 2014; 15:159.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 25543667; PMCID: PMC4301661; DOI: 10.1186/s12863-014-0159-7;

Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. JAMA Neurol. 2014 Nov; 71(11):1394-404.View Related Profiles.

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PMID: 25199842; PMCID: PMC4314944; DOI: 10.1001/jamaneurol.2014.1491;

Lin H, Joehanes R, Pilling LC, Dupuis J, Lunetta KL, Ying SX, Benjamin EJ, Hernandez D, Singleton A, Melzer D, Munson PJ, Levy D, Ferrucci L, Murabito JM. Whole blood gene expression and interleukin-6 levels. Genomics. 2014 Dec; 104(6 Pt B):490-5.View Related Profiles.

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Benjamin, Emelia
Lin, Honghuang
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PMID: 25311648; PMCID: PMC4262595; DOI: 10.1016/j.ygeno.2014.10.003;

Lüneburg N, Lieb W, Zeller T, Chen MH, Maas R, Carter AM, Xanthakis V, Glazer NL, Schwedhelm E, Seshadri S, Ikram MA, Longstreth WT, Fornage M, König IR, Loley C, Ojeda FM, Schillert A, Wang TJ, Sticht H, Kittel A, König J, Benjamin EJ, Sullivan LM, Bernges I, Anderssohn M, Ziegler A, Gieger C, Illig T, Meisinger C, Wichmann HE, Wild PS, Schunkert H, Psaty BM, Wiggins KL, Heckbert SR, Smith N, Lackner K, Lunetta KL, Blankenberg S, Erdmann J, Munzel T, Grant PJ, Vasan RS, Böger RH. Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine. Circ Cardiovasc Genet. 2014 Dec; 7(6):864-72.View Related Profiles.

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Lunetta, Kathryn
Sullivan, Lisa
Seshadri, Sudha
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Ramachandran, Vasan

PMID: 25245031; PMCID: PMC4797637; DOI: 10.1161/CIRCGENETICS.113.000264;

Palmer JR, Viscidi E, Troester MA, Hong CC, Schedin P, Bethea TN, Bandera EV, Borges V, McKinnon C, Haiman CA, Lunetta K, Kolonel LN, Rosenberg L, Olshan AF, Ambrosone CB. Parity, lactation, and breast cancer subtypes in African American women: results from the AMBER Consortium. J Natl Cancer Inst. 2014 Oct; 106(10).View Related Profiles.

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Lunetta, Kathryn
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Bethea, Traci

PMID: 25224496; PMCID: PMC4271113; DOI: 10.1093/jnci/dju237;

Broer L, Buchman AS, Deelen J, Evans DS, Faul JD, Lunetta KL, Sebastiani P, Smith JA, Smith AV, Tanaka T, Yu L, Arnold AM, Aspelund T, Benjamin EJ, De Jager PL, Eirkisdottir G, Evans DA, Garcia ME, Hofman A, Kaplan RC, Kardia SL, Kiel DP, Oostra BA, Orwoll ES, Parimi N, Psaty BM, Rivadeneira F, Rotter JI, Seshadri S, Singleton A, Tiemeier H, Uitterlinden AG, Zhao W, Bandinelli S, Bennett DA, Ferrucci L, Gudnason V, Harris TB, Karasik D, Launer LJ, Perls TT, Slagboom PE, Tranah GJ, Weir DR, Newman AB, van Duijn CM, Murabito JM. GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy. J Gerontol A Biol Sci Med Sci. 2015 Jan; 70(1):110-8.View Related Profiles.

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Murabito, Joanne
Lunetta, Kathryn
Sebastiani, Paola
Seshadri, Sudha
Perls, Thomas

PMID: 25199915; PMCID: PMC4296168; DOI: 10.1093/gerona/glu166;

Sinner MF, Tucker NR, Lunetta KL, Ozaki K, Smith JG, Trompet S, Bis JC, Lin H, Chung MK, Nielsen JB, Lubitz SA, Krijthe BP, Magnani JW, Ye J, Gollob MH, Tsunoda T, Müller-Nurasyid M, Lichtner P, Peters A, Dolmatova E, Kubo M, Smith JD, Psaty BM, Smith NL, Jukema JW, Chasman DI, Albert CM, Ebana Y, Furukawa T, Macfarlane PW, Harris TB, Darbar D, Dörr M, Holst AG, Svendsen JH, Hofman A, Uitterlinden AG, Gudnason V, Isobe M, Malik R, Dichgans M, Rosand J, Van Wagoner DR, Benjamin EJ, Milan DJ, Melander O, Heckbert SR, Ford I, Liu Y, Barnard J, Olesen MS, Stricker BH, Tanaka T, Kääb S, Ellinor PT. Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation. 2014 Oct 7; 130(15):1225-35.View Related Profiles.

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Lin, Honghuang
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Lunetta, Kathryn

PMID: 25124494; PMCID: PMC4190011; DOI: 10.1161/CIRCULATIONAHA.114.009892;

Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Kim JW, Buxbaum JD, Mayeux R, Ikezu T, Abraham CR, Farrer LA. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Ann Neurol. 2014 Sep; 76(3):379-92.View Related Profiles.

Abraham, Carmela
Chen, Ci-Di
Zeldich, Ella
Jun, Gyungah
Asai, Hirohide
Chung, Jaeyoon
Lunetta, Kathryn
Farrer, Lindsay
Ikezu, Tsuneya

PMID: 25043464; PMCID: PMC4830273; DOI: 10.1002/ana.24219;

Perry JR, Day F, Elks CE, Sulem P, Thompson DJ, Ferreira T, He C, Chasman DI, Esko T, Thorleifsson G, Albrecht E, Ang WQ, Corre T, Cousminer DL, Feenstra B, Franceschini N, Ganna A, Johnson AD, Kjellqvist S, Lunetta KL, McMahon G, Nolte IM, Paternoster L, Porcu E, Smith AV, Stolk L, Teumer A, Tšernikova N, Tikkanen E, Ulivi S, Wagner EK, Amin N, Bierut LJ, Byrne EM, Hottenga JJ, Koller DL, Mangino M, Pers TH, Yerges-Armstrong LM, Hua Zhao J, Andrulis IL, Anton-Culver H, Atsma F, Bandinelli S, Beckmann MW, Benitez J, Blomqvist C, Bojesen SE, Bolla MK, Bonanni B, Brauch H, Brenner H, Buring JE, Chang-Claude J, Chanock S, Chen J, Chenevix-Trench G, Collée JM, Couch FJ, Couper D, Coviello AD, Cox A, Czene K, D'adamo AP, Davey Smith G, De Vivo I, Demerath EW, Dennis J, Devilee P, Dieffenbach AK, Dunning AM, Eiriksdottir G, Eriksson JG, Fasching PA, Ferrucci L, Flesch-Janys D, Flyger H, Foroud T, Franke L, Garcia ME, García-Closas M, Geller F, de Geus EE, Giles GG, Gudbjartsson DF, Gudnason V, Guénel P, Guo S, Hall P, Hamann U, Haring R, Hartman CA, Heath AC, Hofman A, Hooning MJ, Hopper JL, Hu FB, Hunter DJ, Karasik D, Kiel DP, Knight JA, Kosma VM, Kutalik Z, Lai S, Lambrechts D, Lindblom A, Mägi R, Magnusson PK, Mannermaa A, Martin NG, Masson G, McArdle PF, McArdle WL, Melbye M, Michailidou K, Mihailov E, Milani L, Milne RL, Nevanlinna H, Neven P, Nohr EA, Oldehinkel AJ, Oostra BA, Palotie A, Peacock M, Pedersen NL, Peterlongo P, Peto J, Pharoah PD, Postma DS, Pouta A, Pylkäs K, Radice P, Ring S, Rivadeneira F, Robino A, Rose LM, Rudolph A, Salomaa V, Sanna S, Schlessinger D, Schmidt MK, Southey MC, Sovio U, Stampfer MJ, Stöckl D, Storniolo AM, Timpson NJ, Tyrer J, Visser JA, Vollenweider P, Völzke H, Waeber G, Waldenberger M, Wallaschofski H, Wang Q, Willemsen G, Winqvist R, Wolffenbuttel BH, Wright MJ, Boomsma DI, Econs MJ, Khaw KT, Loos RJ, McCarthy MI, Montgomery GW, Rice JP, Streeten EA, Thorsteinsdottir U, van Duijn CM, Alizadeh BZ, Bergmann S, Boerwinkle E, Boyd HA, Crisponi L, Gasparini P, Gieger C, Harris TB, Ingelsson E, Järvelin MR, Kraft P, Lawlor D, Metspalu A, Pennell CE, Ridker PM, Snieder H, Sørensen TI, Spector TD, Strachan DP, Uitterlinden AG, Wareham NJ, Widen E, Zygmunt M, Murray A, Easton DF, Stefansson K, Murabito JM, Ong KK. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. Nature. 2014 Oct 2; 514(7520):92-7.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 25231870; PMCID: PMC4185210; DOI: 10.1038/nature13545;

Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J; Cardiovascular Health Study (CHS). . Gene-wide analysis detects two new susceptibility genes for Alzheimer''s disease. PLoS One. 2014; 9(6):e94661.

Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG, Bressler J, Liu X, Davis BC, Johnson AD, O'Donnell CJ, Kovar CL, Dinh H, Wu Y, Newsham I, Chen H, Broka A, DeStefano AL, Gupta M, Lunetta KL, Liu CT, White CC, Xing C, Zhou Y, Benjamin EJ, Schnabel RB, Heckbert SR, Psaty BM, Muzny DM, Cupples LA, Morrison AC, Boerwinkle E. Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):335-43.View Related Profiles.

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Lin, Honghuang
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Cupples, L
Gupta, Mayetri

PMID: 24951659; PMCID: PMC4176824; DOI: 10.1161/CIRCGENETICS.113.000350;

Lin H, Yin X, Lunetta KL, Dupuis J, McManus DD, Lubitz SA, Magnani JW, Joehanes R, Munson PJ, Larson MG, Levy D, Ellinor PT, Benjamin EJ. Whole blood gene expression and atrial fibrillation: the Framingham Heart Study. PLoS One. 2014; 9(5):e96794.View Related Profiles.

Levy, Daniel
Benjamin, Emelia
Lin, Honghuang
Magnani, Jared
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin
Yin, Xiaoyan

PMID: 24805109; PMCID: PMC4013062; DOI: 10.1371/journal.pone.0096794;

Macri V, Mahida SN, Zhang ML, Sinner MF, Dolmatova EV, Tucker NR, McLellan M, Shea MA, Milan DJ, Lunetta KL, Benjamin EJ, Ellinor PT. A novel trafficking-defective HCN4 mutation is associated with early-onset atrial fibrillation. Heart Rhythm. 2014 Jun; 11(6):1055-62.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 24607718; PMCID: PMC4130372; DOI: 10.1016/j.hrthm.2014.03.002;

Lubitz SA, Lunetta KL, Lin H, Arking DE, Trompet S, Li G, Krijthe BP, Chasman DI, Barnard J, Kleber ME, Dörr M, Ozaki K, Smith AV, Müller-Nurasyid M, Walter S, Agarwal SK, Bis JC, Brody JA, Chen LY, Everett BM, Ford I, Franco OH, Harris TB, Hofman A, Kääb S, Mahida S, Kathiresan S, Kubo M, Launer LJ, Macfarlane PW, Magnani JW, McKnight B, McManus DD, Peters A, Psaty BM, Rose LM, Rotter JI, Silbernagel G, Smith JD, Sotoodehnia N, Stott DJ, Taylor KD, Tomaschitz A, Tsunoda T, Uitterlinden AG, Van Wagoner DR, Völker U, Völzke H, Murabito JM, Sinner MF, Gudnason V, Felix SB, März W, Chung M, Albert CM, Stricker BH, Tanaka T, Heckbert SR, Jukema JW, Alonso A, Benjamin EJ, Ellinor PT. Novel genetic markers associate with atrial fibrillation risk in Europeans and Japanese. J Am Coll Cardiol. 2014 Apr 1; 63(12):1200-10.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Magnani, Jared
Murabito, Joanne
Lunetta, Kathryn

PMID: 24486271; PMCID: PMC4009240; DOI: 10.1016/j.jacc.2013.12.015;

Mez J, Chung J, Schu M, Logue MW, Jun G, Lunetta KL, Farrer LA. A VARIANT IN STK24 ACHIEVES GENOME-WIDE SIGNIFICANCE IN AFRICAN AMERICANS USING A LIABILITY MODEL. Alzheimer's and Dementia. 2014; 10(4). View Publication
Bandera EV, Chandran U, Hong CC, Ambrosone CB, Troester M, Lunetta KL, Adams-Campbell L, Olshan A, Palmer JR, Rosenberg L. Abstract LB-285: Obesity and breast cancer subtypes in African American women participating in the AMBER Consortium. Cancer Research. 2014; 74(19 suppl):LB285. View Publication
Bethea TN, Rosenberg L, Hong CC, Troester MA, Lunetta KL, Bandera EV, Schedin P, Borges VF, Olshan AF, Ambrosone CB, Palmer JR. Abstract B31: Oral contraceptive use in relation to breast cancer subtypes in African American women: Results from the AMBER Consortium. Cancer Epidemiology Biomarkers & Prevention. 2014; 23(11 suppl):B31. View Publication
Jones IR, Lambert JC, Wang LS, PA Holmans, Lunetta KL, Choi SH, Harold D, Vedernikov A et. al. Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimer's and Dementia. 2014; 11(6). View Publication

Logue MW, Schu M, Vardarajan BN, Farrell J, Lunetta KL, Jun G, Baldwin CT, Deangelis MM, Farrer LA. Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways. Neurobiol Aging. 2014 Jun; 35(6):1510.e7-18.View Related Profiles.

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PMID: 24439028; PMCID: PMC3961547; DOI: 10.1016/j.neurobiolaging.2013.12.007;

Yao C, Joehanes R, Johnson AD, Huan T, Esko T, Ying S, Freedman JE, Murabito J, Lunetta KL, Metspalu A, Munson PJ, Levy D. Sex- and age-interacting eQTLs in human complex diseases. Hum Mol Genet. 2014 Apr 1; 23(7):1947-56.View Related Profiles.

Freedman, Jane
Murabito, Joanne
Lunetta, Kathryn

PMID: 24242183; PMCID: PMC3943525; DOI: 10.1093/hmg/ddt582;

Lin H, Sinner MF, Brody JA, Arking DE, Lunetta KL, Rienstra M, Lubitz SA, Magnani JW, Sotoodehnia N, McKnight B, McManus DD, Boerwinkle E, Psaty BM, Rotter JI, Bis JC, Gibbs RA, Muzny D, Kovar CL, Morrison AC, Gupta M, Folsom AR, Kääb S, Heckbert SR, Alonso A, Ellinor PT, Benjamin EJ. Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. Heart Rhythm. 2014 Mar; 11(3):452-7.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Magnani, Jared
Lunetta, Kathryn
Gupta, Mayetri

PMID: 24239840; PMCID: PMC3943920; DOI: 10.1016/j.hrthm.2013.11.012;

Lin H, Dolmatova EV, Morley MP, Lunetta KL, McManus DD, Magnani JW, Margulies KB, Hakonarson H, del Monte F, Benjamin EJ, Cappola TP, Ellinor PT. Gene expression and genetic variation in human atria. Heart Rhythm. 2014 Feb; 11(2):266-71.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Magnani, Jared
Lunetta, Kathryn

PMID: 24177373; PMCID: PMC3946863; DOI: 10.1016/j.hrthm.2013.10.051;

Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet. 2013 Dec; 45(12):1452-8.View Related Profiles.

DeStefano, Anita
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Wolf, Philip
Choi, Seung Hoan
Seshadri, Sudha

PMID: 24162737; PMCID: PMC3896259; DOI: 10.1038/ng.2802;

Mihaescu R, Pencina MJ, Alonso A, Lunetta KL, Heckbert SR, Benjamin EJ, Jw Janssens AC. Incremental value of rare genetic variants for the prediction of multifactorial diseases. Genome Med. 2013; 5(8):76.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Pencina, Michael

PMID: 23961719; PMCID: PMC3971349; DOI: 10.1186/gm480;

Schilling S, DeStefano AL, Sachdev PS, Choi SH, Mather KA, DeCarli CD, Wen W, Høgh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, Farrer L, Dufouil C, Kuller LH, Mazoyer B, Seshadri S, Tzourio C, Debette S. APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis. Neurology. 2013 Jul 16; 81(3):292-300.View Related Profiles.

Beiser, Alexa
DeStefano, Anita
Romero, Jose
Lunetta, Kathryn
Farrer, Lindsay
Wolf, Philip
Au, Rhoda
Choi, Seung Hoan
Seshadri, Sudha

PMID: 23858411; PMCID: PMC3770168; DOI: 10.1212/WNL.0b013e31829bfda4;

Hendricks AE, Dupuis J, Logue MW, Myers RH, Lunetta KL. Correction for multiple testing in a gene region. Eur J Hum Genet. 2014 Mar; 22(3):414-8.View Related Profiles.

Dupuis, Josee
Lunetta, Kathryn
Logue, Mark
Myers, Richard

PMID: 23838599; PMCID: PMC3925272; DOI: 10.1038/ejhg.2013.144;

Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, McDonald BC, Farlow MR, Ghetti B, Huentelman MJ, Saykin AJ. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics. Mol Psychiatry. 2013 Jul; 18(7):739.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay

PMID: 23787478; PMCID: PMC3777293; DOI: 10.1038/mp.2013.81;

Travison TG, Zhuang WV, Lunetta KL, Karasik D, Bhasin S, Kiel DP, Coviello AD, Murabito JM. The heritability of circulating testosterone, oestradiol, oestrone and sex hormone binding globulin concentrations in men: the Framingham Heart Study. Clin Endocrinol (Oxf). 2014 Feb; 80(2):277-82.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Lunetta, Kathryn
Travison, Thomas

PMID: 23746309; PMCID: PMC3825765; DOI: 10.1111/cen.12260;

Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H, McDonald BC, Farlow MR, Ghetti B, Huentelman MJ, Saykin AJ. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Mol Psychiatry. 2013 Jul; 18(7):781-7.View Related Profiles.

Lunetta, Kathryn
Farrer, Lindsay

PMID: 23608917; PMCID: PMC3777294; DOI: 10.1038/mp.2013.24;

den Hoed M, Eijgelsheim M, Esko T, Brundel BJ, Peal DS, Evans DM, Nolte IM, Segrè AV, Holm H, Handsaker RE, Westra HJ, Johnson T, Isaacs A, Yang J, Lundby A, Zhao JH, Kim YJ, Go MJ, Almgren P, Bochud M, Boucher G, Cornelis MC, Gudbjartsson D, Hadley D, van der Harst P, Hayward C, den Heijer M, Igl W, Jackson AU, Kutalik Z, Luan J, Kemp JP, Kristiansson K, Ladenvall C, Lorentzon M, Montasser ME, Njajou OT, O'Reilly PF, Padmanabhan S, St Pourcain B, Rankinen T, Salo P, Tanaka T, Timpson NJ, Vitart V, Waite L, Wheeler W, Zhang W, Draisma HH, Feitosa MF, Kerr KF, Lind PA, Mihailov E, Onland-Moret NC, Song C, Weedon MN, Xie W, Yengo L, Absher D, Albert CM, Alonso A, Arking DE, de Bakker PI, Balkau B, Barlassina C, Benaglio P, Bis JC, Bouatia-Naji N, Brage S, Chanock SJ, Chines PS, Chung M, Darbar D, Dina C, Dörr M, Elliott P, Felix SB, Fischer K, Fuchsberger C, de Geus EJ, Goyette P, Gudnason V, Harris TB, Hartikainen AL, Havulinna AS, Heckbert SR, Hicks AA, Hofman A, Holewijn S, Hoogstra-Berends F, Hottenga JJ, Jensen MK, Johansson A, Junttila J, Kääb S, Kanon B, Ketkar S, Khaw KT, Knowles JW, Kooner AS, Kors JA, Kumari M, Milani L, Laiho P, Lakatta EG, Langenberg C, Leusink M, Liu Y, Luben RN, Lunetta KL, Lynch SN, Markus MR, Marques-Vidal P, Mateo Leach I, McArdle WL, McCarroll SA, Medland SE, Miller KA, Montgomery GW, Morrison AC, Müller-Nurasyid M, Navarro P, Nelis M, O'Connell JR, O'Donnell CJ, Ong KK, Newman AB, Peters A, Polasek O, Pouta A, Pramstaller PP, Psaty BM, Rao DC, Ring SM, Rossin EJ, Rudan D, Sanna S, Scott RA, Sehmi JS, Sharp S, Shin JT, Singleton AB, Smith AV, Soranzo N, Spector TD, Stewart C, Stringham HM, Tarasov KV, Uitterlinden AG, Vandenput L, Hwang SJ, Whitfield JB, Wijmenga C, Wild SH, Willemsen G, Wilson JF, Witteman JC, Wong A, Wong Q, Jamshidi Y, Zitting P, Boer JM, Boomsma DI, Borecki IB, van Duijn CM, Ekelund U, Forouhi NG, Froguel P, Hingorani A, Ingelsson E, Kivimaki M, Kronmal RA, Kuh D, Lind L, Martin NG, Oostra BA, Pedersen NL, Quertermous T, Rotter JI, van der Schouw YT, Verschuren WM, Walker M, Albanes D, Arnar DO, Assimes TL, Bandinelli S, Boehnke M, de Boer RA, Bouchard C, Caulfield WL, Chambers JC, Curhan G, Cusi D, Eriksson J, Ferrucci L, van Gilst WH, Glorioso N, de Graaf J, Groop L, Gyllensten U, Hsueh WC, Hu FB, Huikuri HV, Hunter DJ, Iribarren C, Isomaa B, Jarvelin MR, Jula A, Kähönen M, Kiemeney LA, van der Klauw MM, Kooner JS, Kraft P, Iacoviello L, Lehtimäki T, Lokki ML, Mitchell BD, Navis G, Nieminen MS, Ohlsson C, Poulter NR, Qi L, Raitakari OT, Rimm EB, Rioux JD, Rizzi F, Rudan I, Salomaa V, Sever PS, Shields DC, Shuldiner AR, Sinisalo J, Stanton AV, Stolk RP, Strachan DP, Tardif JC, Thorsteinsdottir U, Tuomilehto J, van Veldhuisen DJ, Virtamo J, Viikari J, Vollenweider P, Waeber G, Widen E, Cho YS, Olsen JV, Visscher PM, Willer C, Franke L, Erdmann J, Thompson JR, Pfeufer A, Sotoodehnia N, Newton-Cheh C, Ellinor PT, Stricker BH, Metspalu A, Perola M, Beckmann JS, Smith GD, Stefansson K, Wareham NJ, Munroe PB, Sibon OC, Milan DJ, Snieder H, Samani NJ, Loos RJ. Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders. Nat Genet. 2013 Jun; 45(6):621-31.View Related Profiles.

O'Donnell, Christopher
Lunetta, Kathryn
Hwang, Shih-Jen

PMID: 23583979; PMCID: PMC3696959; DOI: 10.1038/ng.2610;

Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, Raj T, Ertekin-Taner N, Logue M, Baldwin CT, Green RC, Barnes LL, Cantwell LB, Fallin MD, Go RC, Griffith P, Obisesan TO, Manly JJ, Lunetta KL, Kamboh MI, Lopez OL, Bennett DA, Hendrie H, Hall KS, Goate AM, Byrd GS, Kukull WA, Foroud TM, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Mayeux R. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ?4,and the risk of late-onset Alzheimer disease in African Americans. JAMA. 2013 Apr 10; 309(14):1483-92.View Related Profiles.

Baldwin, Clinton
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark

PMID: 23571587; PMCID: PMC3667653; DOI: 10.1001/jama.2013.2973;

Fernández-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, McArdle PF, Yerges-Armstrong LM, Elks CE, Strachan DP, Kutalik Z, Vollenweider P, Feenstra B, Boyd HA, Metspalu A, Mihailov E, Broer L, Zillikens MC, Oostra B, van Duijn CM, Lunetta KL, Perry JR, Murray A, Koller DL, Lai D, Corre T, Toniolo D, Albrecht E, Stöckl D, Grallert H, Gieger C, Hayward C, Polasek O, Rudan I, Wilson JF, He C, Kraft P, Hu FB, Hunter DJ, Hottenga JJ, Willemsen G, Boomsma DI, Byrne EM, Martin NG, Montgomery GW, Warrington NM, Pennell CE, Stolk L, Visser JA, Hofman A, Uitterlinden AG, Rivadeneira F, Lin P, Fisher SL, Bierut LJ, Crisponi L, Porcu E, Mangino M, Zhai G, Spector TD, Buring JE, Rose LM, Ridker PM, Poole C, Hirschhorn JN, Murabito JM, Chasman DI, Widen E, North KE, Ong KK, Franceschini N. Association of adiposity genetic variants with menarche timing in 92,105 women of European descent. Am J Epidemiol. 2013 Aug 1; 178(3):451-60.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 23558354; PMCID: PMC3816344; DOI: 10.1093/aje/kws473;

Perry JR, Corre T, Esko T, Chasman DI, Fischer K, Franceschini N, He C, Kutalik Z, Mangino M, Rose LM, Vernon Smith A, Stolk L, Sulem P, Weedon MN, Zhuang WV, Arnold A, Ashworth A, Bergmann S, Buring JE, Burri A, Chen C, Cornelis MC, Couper DJ, Goodarzi MO, Gudnason V, Harris T, Hofman A, Jones M, Kraft P, Launer L, Laven JS, Li G, McKnight B, Masciullo C, Milani L, Orr N, Psaty BM, Ridker PM, Rivadeneira F, Sala C, Salumets A, Schoemaker M, Traglia M, Waeber G, Chanock SJ, Demerath EW, Garcia M, Hankinson SE, Hu FB, Hunter DJ, Lunetta KL, Metspalu A, Montgomery GW, Murabito JM, Newman AB, Ong KK, Spector TD, Stefansson K, Swerdlow AJ, Thorsteinsdottir U, Van Dam RM, Uitterlinden AG, Visser JA, Vollenweider P, Toniolo D, Murray A. A genome-wide association study of early menopause and the combined impact of identified variants. Hum Mol Genet. 2013 Apr 1; 22(7):1465-72.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 23307926; PMCID: PMC3596848; DOI: 10.1093/hmg/dds551;

Hek K, Demirkan A, Lahti J, Terracciano A, Teumer A, Cornelis MC, Amin N, Bakshis E, Baumert J, Ding J, Liu Y, Marciante K, Meirelles O, Nalls MA, Sun YV, Vogelzangs N, Yu L, Bandinelli S, Benjamin EJ, Bennett DA, Boomsma D, Cannas A, Coker LH, de Geus E, De Jager PL, Diez-Roux AV, Purcell S, Hu FB, Rimm EB, Hunter DJ, Jensen MK, Curhan G, Rice K, Penman AD, Rotter JI, Sotoodehnia N, Emeny R, Eriksson JG, Evans DA, Ferrucci L, Fornage M, Gudnason V, Hofman A, Illig T, Kardia S, Kelly-Hayes M, Koenen K, Kraft P, Kuningas M, Massaro JM, Melzer D, Mulas A, Mulder CL, Murray A, Oostra BA, Palotie A, Penninx B, Petersmann A, Pilling LC, Psaty B, Rawal R, Reiman EM, Schulz A, Shulman JM, Singleton AB, Smith AV, Sutin AR, Uitterlinden AG, Völzke H, Widen E, Yaffe K, Zonderman AB, Cucca F, Harris T, Ladwig KH, Llewellyn DJ, Räikkönen K, Tanaka T, van Duijn CM, Grabe HJ, Launer LJ, Lunetta KL, Mosley TH, Newman AB, Tiemeier H, Murabito J. A genome-wide association study of depressive symptoms. Biol Psychiatry. 2013 Apr 1; 73(7):667-78.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Massaro, Joseph
Lunetta, Kathryn
Kelly-Hayes, Margaret

PMID: 23290196; PMCID: PMC3845085; DOI: 10.1016/j.biopsych.2012.09.033;

Lunetta KL. Methods for meta-analysis of genetic data. Curr Protoc Hum Genet. 2013; Chapter 1:Unit1.24. PMID: 23595597; DOI: 10.1002/0471142905.hg0124s77;

Whitcomb DC, LaRusch J, Krasinskas AM, Klei L, Smith JP, Brand RE, Neoptolemos JP, Lerch MM, Tector M, Sandhu BS, Guda NM, Orlichenko L, Alkaade S, Amann ST, Anderson MA, Baillie J, Banks PA, Conwell D, Coté GA, Cotton PB, DiSario J, Farrer LA, Forsmark CE, Johnstone M, Gardner TB, Gelrud A, Greenhalf W, Haines JL, Hartman DJ, Hawes RA, Lawrence C, Lewis M, Mayerle J, Mayeux R, Melhem NM, Money ME, Muniraj T, Papachristou GI, Pericak-Vance MA, Romagnuolo J, Schellenberg GD, Sherman S, Simon P, Singh VP, Slivka A, Stolz D, Sutton R, Weiss FU, Wilcox CM, Zarnescu NO, Wisniewski SR, O'Connell MR, Kienholz ML, Roeder K, Barmada MM, Yadav D, Devlin B. Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis. Nat Genet. 2012 Dec; 44(12):1349-54.View Related Profiles.

Baldwin, Clinton
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Kowall, Neil
Stern, Robert

PMID: 23143602; PMCID: PMC3510344; DOI: 10.1038/ng.2466;

Hadzi TC, Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Gillis T, Mysore JS, Gusella JF, MacDonald ME, Myers RH, Vonsattel JP. Assessment of cortical and striatal involvement in 523 Huntington disease brains. Neurology. 2012 Oct 16; 79(16):1708-15.View Related Profiles.

Latourelle, Jeanne
Lunetta, Kathryn
Cupples, L
Myers, Richard

PMID: 23035064; PMCID: PMC3468776; DOI: 10.1212/WNL.0b013e31826e9a5d;

Jun G, Vardarajan BN, Buros J, Yu CE, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL, Lunetta KL, Pericak-Vance MA, Schellenberg GD, Farrer LA. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Arch Neurol. 2012 Oct; 69(10):1270-9.View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay

PMID: 22869155; PMCID: PMC3579659; DOI: 10.1001/archneurol.2012.2052;

Liu CT, Ng MC, Rybin D, Adeyemo A, Bielinski SJ, Boerwinkle E, Borecki I, Cade B, Chen YD, Djousse L, Fornage M, Goodarzi MO, Grant SF, Guo X, Harris T, Kabagambe E, Kizer JR, Liu Y, Lunetta KL, Mukamal K, Nettleton JA, Pankow JS, Patel SR, Ramos E, Rasmussen-Torvik L, Rich SS, Rotimi CN, Sarpong D, Shriner D, Sims M, Zmuda JM, Redline S, Kao WH, Siscovick D, Florez JC, Rotter JI, Dupuis J, Wilson JG, Bowden DW, Meigs JB. Transferability and fine-mapping of glucose and insulin quantitative trait loci across populations: CARe, the Candidate Gene Association Resource. Diabetologia. 2012 Nov; 55(11):2970-84.View Related Profiles.

Liu, Ching-Ti
Dupuis, Josee
Lunetta, Kathryn

PMID: 22893027; PMCID: PMC3804308; DOI: 10.1007/s00125-012-2656-4;

Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V, Mangino M, Onland-Moret NC, Chen B, Eriksson J, Garcia M, Liu YM, Koster A, Lohman K, Lyytikäinen LP, Petersen AK, Prescott J, Stolk L, Vandenput L, Wood AR, Zhuang WV, Ruokonen A, Hartikainen AL, Pouta A, Bandinelli S, Biffar R, Brabant G, Cox DG, Chen Y, Cummings S, Ferrucci L, Gunter MJ, Hankinson SE, Martikainen H, Hofman A, Homuth G, Illig T, Jansson JO, Johnson AD, Karasik D, Karlsson M, Kettunen J, Kiel DP, Kraft P, Liu J, Ljunggren Ö, Lorentzon M, Maggio M, Markus MR, Mellström D, Miljkovic I, Mirel D, Nelson S, Morin Papunen L, Peeters PH, Prokopenko I, Raffel L, Reincke M, Reiner AP, Rexrode K, Rivadeneira F, Schwartz SM, Siscovick D, Soranzo N, Stöckl D, Tworoger S, Uitterlinden AG, van Gils CH, Vasan RS, Wichmann HE, Zhai G, Bhasin S, Bidlingmaier M, Chanock SJ, De Vivo I, Harris TB, Hunter DJ, Kähönen M, Liu S, Ouyang P, Spector TD, van der Schouw YT, Viikari J, Wallaschofski H, McCarthy MI, Frayling TM, Murray A, Franks S, Järvelin MR, de Jong FH, Raitakari O, Teumer A, Ohlsson C, Murabito JM, Perry JR. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 2012; 8(7):e1002805.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 22829776; PMCID: PMC3400553; DOI: 10.1371/journal.pgen.1002805;

Hendricks AE, Dupuis J, Gupta M, Logue MW, Lunetta KL. A comparison of gene region simulation methods. PLoS One. 2012; 7(7):e40925.View Related Profiles.

Dupuis, Josee
Lunetta, Kathryn
Logue, Mark
Gupta, Mayetri

PMID: 22815869; PMCID: PMC3399793; DOI: 10.1371/journal.pone.0040925;

Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA. Multiple loci influencing hippocampal degeneration identified by genome scan. Ann Neurol. 2012 Jul; 72(1):65-75.View Related Profiles.

Baldwin, Clinton
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Logue, Mark
Melville, Scott

PMID: 22745009; PMCID: PMC3405172; DOI: 10.1002/ana.23644;

Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 2012 Jul 17; 79(3):221-8.View Related Profiles.

McKee, Ann
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Kowall, Neil
Stern, Robert

PMID: 22722634; PMCID: PMC3398432; DOI: 10.1212/WNL.0b013e3182605801;

Broer L, Demerath EW, Garcia ME, Homuth G, Kaplan RC, Lunetta KL, Tanaka T, Tranah GJ, Walter S, Arnold AM, Atzmon G, Harris TB, Hoffmann W, Karasik D, Kiel DP, Kocher T, Launer LJ, Lohman KK, Rotter JI, Tiemeier H, Uitterlinden AG, Wallaschofski H, Bandinelli S, Dörr M, Ferrucci L, Franceschini N, Gudnason V, Hofman A, Liu Y, Murabito JM, Newman AB, Oostra BA, Psaty BM, Smith AV, van Duijn CM. Association of heat shock proteins with all-cause mortality. Age (Dordr). 2013 Aug; 35(4):1367-76.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 22555621; PMCID: PMC3705092; DOI: 10.1007/s11357-012-9417-7;

Ellinor PT, Lunetta KL, Albert CM, Glazer NL, Ritchie MD, Smith AV, Arking DE, Müller-Nurasyid M, Krijthe BP, Lubitz SA, Bis JC, Chung MK, Dörr M, Ozaki K, Roberts JD, Smith JG, Pfeufer A, Sinner MF, Lohman K, Ding J, Smith NL, Smith JD, Rienstra M, Rice KM, Van Wagoner DR, Magnani JW, Wakili R, Clauss S, Rotter JI, Steinbeck G, Launer LJ, Davies RW, Borkovich M, Harris TB, Lin H, Völker U, Völzke H, Milan DJ, Hofman A, Boerwinkle E, Chen LY, Soliman EZ, Voight BF, Li G, Chakravarti A, Kubo M, Tedrow UB, Rose LM, Ridker PM, Conen D, Tsunoda T, Furukawa T, Sotoodehnia N, Xu S, Kamatani N, Levy D, Nakamura Y, Parvez B, Mahida S, Furie KL, Rosand J, Muhammad R, Psaty BM, Meitinger T, Perz S, Wichmann HE, Witteman JC, Kao WH, Kathiresan S, Roden DM, Uitterlinden AG, Rivadeneira F, McKnight B, Sjögren M, Newman AB, Liu Y, Gollob MH, Melander O, Tanaka T, Stricker BH, Felix SB, Alonso A, Darbar D, Barnard J, Chasman DI, Heckbert SR, Benjamin EJ, Gudnason V, Kääb S. Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet. 2012 Jun; 44(6):670-5.View Related Profiles.

Benjamin, Emelia
Lin, Honghuang
Magnani, Jared
Lunetta, Kathryn

PMID: 22544366; PMCID: PMC3366038; DOI: 10.1038/ng.2261;

Murabito JM, Yuan R, Lunetta KL. The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals. J Gerontol A Biol Sci Med Sci. 2012 May; 67(5):470-9.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 22499766; PMCID: PMC3326242; DOI: 10.1093/gerona/gls089;

He C, Chasman DI, Dreyfus J, Hwang SJ, Ruiter R, Sanna S, Buring JE, Fernández-Rhodes L, Franceschini N, Hankinson SE, Hofman A, Lunetta KL, Palmieri G, Porcu E, Rivadeneira F, Rose LM, Splansky GL, Stolk L, Uitterlinden AG, Chanock SJ, Crisponi L, Demerath EW, Murabito JM, Ridker PM, Stricker BH, Hunter DJ. Reproductive aging-associated common genetic variants and the risk of breast cancer. Breast Cancer Res. 2012; 14(2):R54.View Related Profiles.

Murabito, Joanne
Buring, Julie
Lunetta, Kathryn
Hwang, Shih-Jen

PMID: 22433456; PMCID: PMC3446388; DOI: 10.1186/bcr3155;

Stolk L, Perry JR, Chasman DI, He C, Mangino M, Sulem P, Barbalic M, Broer L, Byrne EM, Ernst F, Esko T, Franceschini N, Gudbjartsson DF, Hottenga JJ, Kraft P, McArdle PF, Porcu E, Shin SY, Smith AV, van Wingerden S, Zhai G, Zhuang WV, Albrecht E, Alizadeh BZ, Aspelund T, Bandinelli S, Lauc LB, Beckmann JS, Boban M, Boerwinkle E, Broekmans FJ, Burri A, Campbell H, Chanock SJ, Chen C, Cornelis MC, Corre T, Coviello AD, d'Adamo P, Davies G, de Faire U, de Geus EJ, Deary IJ, Dedoussis GV, Deloukas P, Ebrahim S, Eiriksdottir G, Emilsson V, Eriksson JG, Fauser BC, Ferreli L, Ferrucci L, Fischer K, Folsom AR, Garcia ME, Gasparini P, Gieger C, Glazer N, Grobbee DE, Hall P, Haller T, Hankinson SE, Hass M, Hayward C, Heath AC, Hofman A, Ingelsson E, Janssens AC, Johnson AD, Karasik D, Kardia SL, Keyzer J, Kiel DP, Kolcic I, Kutalik Z, Lahti J, Lai S, Laisk T, Laven JS, Lawlor DA, Liu J, Lopez LM, Louwers YV, Magnusson PK, Marongiu M, Martin NG, Klaric IM, Masciullo C, McKnight B, Medland SE, Melzer D, Mooser V, Navarro P, Newman AB, Nyholt DR, Onland-Moret NC, Palotie A, Paré G, Parker AN, Pedersen NL, Peeters PH, Pistis G, Plump AS, Polasek O, Pop VJ, Psaty BM, Räikkönen K, Rehnberg E, Rotter JI, Rudan I, Sala C, Salumets A, Scuteri A, Singleton A, Smith JA, Snieder H, Soranzo N, Stacey SN, Starr JM, Stathopoulou MG, Stirrups K, Stolk RP, Styrkarsdottir U, Sun YV, Tenesa A, Thorand B, Toniolo D, Tryggvadottir L, Tsui K, Ulivi S, van Dam RM, van der Schouw YT, van Gils CH, van Nierop P, Vink JM, Visscher PM, Voorhuis M, Waeber G, Wallaschofski H, Wichmann HE, Widen E, Wijnands-van Gent CJ, Willemsen G, Wilson JF, Wolffenbuttel BH, Wright AF, Yerges-Armstrong LM, Zemunik T, Zgaga L, Zillikens MC, Zygmunt M, Study TL, Arnold AM, Boomsma DI, Buring JE, Crisponi L, Demerath EW, Gudnason V, Harris TB, Hu FB, Hunter DJ, Launer LJ, Metspalu A, Montgomery GW, Oostra BA, Ridker PM, Sanna S, Schlessinger D, Spector TD, Stefansson K, Streeten EA, Thorsteinsdottir U, Uda M, Uitterlinden AG, van Duijn CM, Völzke H, Murray A, Murabito JM, Visser JA, Lunetta KL. Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. Nat Genet. 2012 Mar; 44(3):260-8.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 22267201; PMCID: PMC3288642; DOI: 10.1038/ng.1051;

Murabito JM, Lunetta KL. The Epidemiology of Aging. Genetics of Human Longevity and Healthy Aging. 2012; 215-235. View Publication

Logue MW, Schu M, Vardarajan BN, Buros J, Green RC, Go RC, Griffith P, Obisesan TO, Shatz R, Borenstein A, Cupples LA, Lunetta KL, Fallin MD, Baldwin CT, Farrer LA. A comprehensive genetic association study of Alzheimer disease in African Americans. Arch Neurol. 2011 Dec; 68(12):1569-79.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Logue, Mark

PMID: 22159054; PMCID: PMC3356921; DOI: 10.1001/archneurol.2011.646;

Ohlsson C, Wallaschofski H, Lunetta KL, Stolk L, Perry JR, Koster A, Petersen AK, Eriksson J, Lehtimäki T, Huhtaniemi IT, Hammond GL, Maggio M, Coviello AD, Ferrucci L, Heier M, Hofman A, Holliday KL, Jansson JO, Kähönen M, Karasik D, Karlsson MK, Kiel DP, Liu Y, Ljunggren O, Lorentzon M, Lyytikäinen LP, Meitinger T, Mellström D, Melzer D, Miljkovic I, Nauck M, Nilsson M, Penninx B, Pye SR, Vasan RS, Reincke M, Rivadeneira F, Tajar A, Teumer A, Uitterlinden AG, Ulloor J, Viikari J, Völker U, Völzke H, Wichmann HE, Wu TS, Zhuang WV, Ziv E, Wu FC, Raitakari O, Eriksson A, Bidlingmaier M, Harris TB, Murray A, de Jong FH, Murabito JM, Bhasin S, Vandenput L, Haring R. Genetic determinants of serum testosterone concentrations in men. PLoS Genet. 2011 Oct; 7(10):e1002313.View Related Profiles.

Coviello, Andrea
Ulloor, Jagadish
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
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PMID: 21998597; PMCID: PMC3188559; DOI: 10.1371/journal.pgen.1002313;

Schnabel RB, Kerr KF, Lubitz SA, Alkylbekova EL, Marcus GM, Sinner MF, Magnani JW, Wolf PA, Deo R, Lloyd-Jones DM, Lunetta KL, Mehra R, Levy D, Fox ER, Arking DE, Mosley TH, Müller-Nurasyid M, Young TR, Wichmann HE, Seshadri S, Farlow DN, Rotter JI, Soliman EZ, Glazer NL, Wilson JG, Breteler MM, Sotoodehnia N, Newton-Cheh C, Kääb S, Ellinor PT, Alonso A, Benjamin EJ, Heckbert SR. Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project. Circ Cardiovasc Genet. 2011 Oct; 4(5):557-64.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Lunetta, Kathryn
Wolf, Philip
Seshadri, Sudha

PMID: 21846873; PMCID: PMC3224824; DOI: 10.1161/CIRCGENETICS.110.959197;

Kuningas M, Estrada K, Hsu YH, Nandakumar K, Uitterlinden AG, Lunetta KL, van Duijn CM, Karasik D, Hofman A, Murabito J, Rivadeneira F, Kiel DP, Tiemeier H. Large common deletions associate with mortality at old age. Hum Mol Genet. 2011 Nov 1; 20(21):4290-6.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 21835882; PMCID: PMC3188993; DOI: 10.1093/hmg/ddr340;

Govindarajulu US, Lin H, Lunetta KL, D'Agostino RB. Frailty models: Applications to biomedical and genetic studies. Stat Med. 2011 Sep 30; 30(22):2754-64.View Related Profiles.

Lunetta, Kathryn
D'Agostino, Ralph

PMID: 21786277; DOI: 10.1002/sim.4277;

Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman A, Karasik D, Kiel DP, Kocher T, Kuningas M, Launer LJ, Lohman KK, Lutsey PL, Mackenbach J, Marciante K, Psaty BM, Reiman EM, Rotter JI, Seshadri S, Shardell MD, Smith AV, van Duijn C, Walston J, Zillikens MC, Bandinelli S, Baumeister SE, Bennett DA, Ferrucci L, Gudnason V, Kivimaki M, Liu Y, Murabito JM, Newman AB, Tiemeier H, Franceschini N. A genome-wide association study of aging. Neurobiol Aging. 2011 Nov; 32(11):2109.e15-28.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Lunetta, Kathryn
Seshadri, Sudha

PMID: 21782286; PMCID: PMC3193030; DOI: 10.1016/j.neurobiolaging.2011.05.026;

Peloso GM, Lunetta KL. Choice of population structure informative principal components for adjustment in a case-control study. BMC Genet. 2011; 12:64.View Related Profiles.

Peloso, Gina
Lunetta, Kathryn

PMID: 21771328; PMCID: PMC3150322; DOI: 10.1186/1471-2156-12-64;

Coviello AD, Zhuang WV, Lunetta KL, Bhasin S, Ulloor J, Zhang A, Karasik D, Kiel DP, Vasan RS, Murabito JM. Circulating testosterone and SHBG concentrations are heritable in women: the Framingham Heart Study. J Clin Endocrinol Metab. 2011 Sep; 96(9):E1491-5.View Related Profiles.

Coviello, Andrea
Zhang, Anqi
Ulloor, Jagadish
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21752884; PMCID: PMC3167671; DOI: 10.1210/jc.2011-0050;

Ahern TP, Christensen M, Cronin-Fenton DP, Lunetta KL, Søiland H, Gjerde J, Garne JP, Rosenberg CL, Silliman RA, Sørensen HT, Lash TL, Hamilton-Dutoit S. Functional polymorphisms in UDP-glucuronosyl transferases and recurrence in tamoxifen-treated breast cancer survivors. Cancer Epidemiol Biomarkers Prev. 2011 Sep; 20(9):1937-43.View Related Profiles.

Sorensen, Henrik
Lunetta, Kathryn
Silliman, Rebecca

PMID: 21750172; PMCID: PMC3169710; DOI: 10.1158/1055-9965.EPI-11-0419;

Logue MW, Posner H, Green RC, Moline M, Cupples LA, Lunetta KL, Zou H, Hurt SW, Farrer LA, Decarli C. Magnetic resonance imaging-measured atrophy and its relationship to cognitive functioning in vascular dementia and Alzheimer's disease patients. Alzheimers Dement. 2011 Sep; 7(5):493-500.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Logue, Mark

PMID: 21723205; PMCID: PMC3166967; DOI: 10.1016/j.jalz.2011.01.004;

Peloso GM, Dupuis J, Lunetta KL. Evaluation of methods accounting for population structure with pedigree data and continuous outcomes. Genet Epidemiol. 2011 Sep; 35(6):427-36.View Related Profiles.

Peloso, Gina
Dupuis, Josee
Lunetta, Kathryn

PMID: 21618600; DOI: 10.1002/gepi.20590;

Zhai G, Teumer A, Stolk L, Perry JR, Vandenput L, Coviello AD, Koster A, Bell JT, Bhasin S, Eriksson J, Eriksson A, Ernst F, Ferrucci L, Frayling TM, Glass D, Grundberg E, Haring R, Hedman AK, Hofman A, Kiel DP, Kroemer HK, Liu Y, Lunetta KL, Maggio M, Lorentzon M, Mangino M, Melzer D, Miljkovic I, Nica A, Penninx BW, Vasan RS, Rivadeneira F, Small KS, Soranzo N, Uitterlinden AG, Völzke H, Wilson SG, Xi L, Zhuang WV, Harris TB, Murabito JM, Ohlsson C, Murray A, de Jong FH, Spector TD, Wallaschofski H. Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms. PLoS Genet. 2011 Apr; 7(4):e1002025.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Lunetta, Kathryn
Bhasin, Shalender
Ramachandran, Vasan

PMID: 21533175; PMCID: PMC3077384; DOI: 10.1371/journal.pgen.1002025;

Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, Evans D, Schneider JA, Carrasquillo MM, Ertekin-Taner N, Younkin SG, Cruchaga C, Kauwe JS, Nowotny P, Kramer P, Hardy J, Huentelman MJ, Myers AJ, Barmada MM, Demirci FY, Baldwin CT, Green RC, Rogaeva E, St George-Hyslop P, Arnold SE, Barber R, Beach T, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Cummings JL, DeCarli C, DeKosky ST, Diaz-Arrastia R, Dick M, Dickson DW, Ellis WG, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Johnson N, Karlawish J, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Lah JJ, Levey AI, Lieberman AP, Lopez OL, Mack WJ, Marson DC, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Parisi JE, Perl DP, Peskind E, Petersen RC, Poon WW, Quinn JF, Rajbhandary RA, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosenberg RN, Sano M, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Van Deerlin VM, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL, Cantwell LB, Dombroski BA, Beekly D, Lunetta KL, Martin ER, Kamboh MI, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011 May; 43(5):436-41.View Related Profiles.

McKee, Ann
Baldwin, Clinton
Jun, Gyungah
Lunetta, Kathryn
Farrer, Lindsay
Kowall, Neil
Stern, Robert

PMID: 21460841; PMCID: PMC3090745; DOI: 10.1038/ng.801;

Lash TL, Cronin-Fenton D, Ahern TP, Rosenberg CL, Lunetta KL, Silliman RA, Garne JP, Sørensen HT, Hellberg Y, Christensen M, Pedersen L, Hamilton-Dutoit S. CYP2D6 inhibition and breast cancer recurrence in a population-based study in Denmark. J Natl Cancer Inst. 2011 Mar 16; 103(6):489-500.View Related Profiles.

Sorensen, Henrik
Lunetta, Kathryn
Silliman, Rebecca

PMID: 21325141; PMCID: PMC3057982; DOI: 10.1093/jnci/djr010;

Sherva R, Baldwin CT, Inzelberg R, Vardarajan B, Cupples LA, Lunetta K, Bowirrat A, Naj A, Pericak-Vance M, Friedland RP, Farrer LA. Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data. J Alzheimers Dis. 2011; 23(2):349-59.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Sherva, Richard

PMID: 21098978; PMCID: PMC3819807; DOI: 10.3233/JAD-2010-100714;

Vardarjan B, Jun G, Buros J, Farrer LA, Lunetta KL. Identification of Gene-Gene Interactions in Alzheimer Disease Using CoOperative Game Theory. Alzheimer's and Dementia. 2011; 7(4). View Publication

Elks CE, Perry JR, Sulem P, Chasman DI, Franceschini N, He C, Lunetta KL, Visser JA, Byrne EM, Cousminer DL, Gudbjartsson DF, Esko T, Feenstra B, Hottenga JJ, Koller DL, Kutalik Z, Lin P, Mangino M, Marongiu M, McArdle PF, Smith AV, Stolk L, van Wingerden SH, Zhao JH, Albrecht E, Corre T, Ingelsson E, Hayward C, Magnusson PK, Smith EN, Ulivi S, Warrington NM, Zgaga L, Alavere H, Amin N, Aspelund T, Bandinelli S, Barroso I, Berenson GS, Bergmann S, Blackburn H, Boerwinkle E, Buring JE, Busonero F, Campbell H, Chanock SJ, Chen W, Cornelis MC, Couper D, Coviello AD, d'Adamo P, de Faire U, de Geus EJ, Deloukas P, Döring A, Smith GD, Easton DF, Eiriksdottir G, Emilsson V, Eriksson J, Ferrucci L, Folsom AR, Foroud T, Garcia M, Gasparini P, Geller F, Gieger C, Gudnason V, Hall P, Hankinson SE, Ferreli L, Heath AC, Hernandez DG, Hofman A, Hu FB, Illig T, Järvelin MR, Johnson AD, Karasik D, Khaw KT, Kiel DP, Kilpeläinen TO, Kolcic I, Kraft P, Launer LJ, Laven JS, Li S, Liu J, Levy D, Martin NG, McArdle WL, Melbye M, Mooser V, Murray JC, Murray SS, Nalls MA, Navarro P, Nelis M, Ness AR, Northstone K, Oostra BA, Peacock M, Palmer LJ, Palotie A, Paré G, Parker AN, Pedersen NL, Peltonen L, Pennell CE, Pharoah P, Polasek O, Plump AS, Pouta A, Porcu E, Rafnar T, Rice JP, Ring SM, Rivadeneira F, Rudan I, Sala C, Salomaa V, Sanna S, Schlessinger D, Schork NJ, Scuteri A, Segrè AV, Shuldiner AR, Soranzo N, Sovio U, Srinivasan SR, Strachan DP, Tammesoo ML, Tikkanen E, Toniolo D, Tsui K, Tryggvadottir L, Tyrer J, Uda M, van Dam RM, van Meurs JB, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Weedon MN, Wichmann HE, Willemsen G, Wilson JF, Wright AF, Young L, Zhai G, Zhuang WV, Bierut LJ, Boomsma DI, Boyd HA, Crisponi L, Demerath EW, van Duijn CM, Econs MJ, Harris TB, Hunter DJ, Loos RJ, Metspalu A, Montgomery GW, Ridker PM, Spector TD, Streeten EA, Stefansson K, Thorsteinsdottir U, Uitterlinden AG, Widen E, Murabito JM, Ong KK, Murray A. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet. 2010 Dec; 42(12):1077-85.View Related Profiles.

Coviello, Andrea
Murabito, Joanne
Buring, Julie
Lunetta, Kathryn

PMID: 21102462; PMCID: PMC3140055; DOI: 10.1038/ng.714;

Wirka RC, Gore S, Van Wagoner DR, Arking DE, Lubitz SA, Lunetta KL, Benjamin EJ, Alonso A, Ellinor PT, Barnard J, Chung MK, Smith JD. A common connexin-40 gene promoter variant affects connexin-40 expression in human atria and is associated with atrial fibrillation. Circ Arrhythm Electrophysiol. 2011 Feb; 4(1):87-93.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 21076161; PMCID: PMC3057452; DOI: 10.1161/CIRCEP.110.959726;

Sinner MF, Lubitz SA, Pfeufer A, Makino S, Beckmann BM, Lunetta KL, Steinbeck G, Perz S, Rahman R, Sonni A, Greenberg SM, Furie KL, Wichmann HE, Meitinger T, Peters A, Benjamin EJ, Rosand J, Ellinor PT, Kääb S. Lack of replication in polymorphisms reported to be associated with atrial fibrillation. Heart Rhythm. 2011 Mar; 8(3):403-9.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 21056700; PMCID: PMC3068750; DOI: 10.1016/j.hrthm.2010.11.003;

Erlich PM, Lunetta KL, Cupples LA, Abraham CR, Green RC, Baldwin CT, Farrer LA. Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. Neurobiol Aging. 2012 May; 33(5):1015.e7-23.View Related Profiles.

Abraham, Carmela
Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 20980077; PMCID: PMC3034817; DOI: 10.1016/j.neurobiolaging.2010.08.003;

Ahern TP, Christensen M, Cronin-Fenton DP, Lunetta KL, Rosenberg CL, Sørensen HT, Lash TL, Hamilton-Dutoit S. Concordance of metabolic enzyme genotypes assayed from paraffin-embedded, formalin-fixed breast tumors and normal lymphatic tissue. Clin Epidemiol. 2010; 2:241-6.View Related Profiles.

Sorensen, Henrik
Lunetta, Kathryn

PMID: 21152250; PMCID: PMC2998813; DOI: 10.2147/CLEP.S13811;

Lubitz SA, Sinner MF, Lunetta KL, Makino S, Pfeufer A, Rahman R, Veltman CE, Barnard J, Bis JC, Danik SP, Sonni A, Shea MA, Del Monte F, Perz S, Müller M, Peters A, Greenberg SM, Furie KL, van Noord C, Boerwinkle E, Stricker BH, Witteman J, Smith JD, Chung MK, Heckbert SR, Benjamin EJ, Rosand J, Arking DE, Alonso A, Kääb S, Ellinor PT. Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation. 2010 Sep 7; 122(10):976-84.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn

PMID: 20733104; PMCID: PMC2978508; DOI: 10.1161/CIRCULATIONAHA.109.886440;

Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, Cantwell LB, Dombroski BA, Saykin AJ, Reiman EM, Bennett DA, Morris JC, Lunetta KL, Martin ER, Montine TJ, Goate AM, Blacker D, Tsuang DW, Beekly D, Cupples LA, Hakonarson H, Kukull W, Foroud TM, Haines J, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol. 2010 Dec; 67(12):1473-84.View Related Profiles.

Jun, Gyungah
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay
Kowall, Neil

PMID: 20697030; PMCID: PMC3048805; DOI: 10.1001/archneurol.2010.201;

Perneczky R, Wagenpfeil S, Lunetta KL, Cupples LA, Green RC, Decarli C, Farrer LA, Kurz A. Head circumference, atrophy, and cognition: implications for brain reserve in Alzheimer disease. Neurology. 2010 Jul 13; 75(2):137-42.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 20625166; PMCID: PMC2905931; DOI: 10.1212/WNL.0b013e3181e7ca97;

Lash TL, Cronin-Fenton D, Ahern TP, Rosenberg CL, Lunetta KL, Silliman RA, Hamilton-Dutoit S, Garne JP, Ewertz M, Sørensen HT, Pedersen L. Breast cancer recurrence risk related to concurrent use of SSRI antidepressants and tamoxifen. Acta Oncol. 2010 Apr; 49(3):305-12.View Related Profiles.

Sorensen, Henrik
Lunetta, Kathryn
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PMID: 20156115; PMCID: PMC2892037; DOI: 10.3109/02841860903575273;

Newman AB, Walter S, Lunetta KL, Garcia ME, Slagboom PE, Christensen K, Arnold AM, Aspelund T, Aulchenko YS, Benjamin EJ, Christiansen L, D'Agostino RB, Fitzpatrick AL, Franceschini N, Glazer NL, Gudnason V, Hofman A, Kaplan R, Karasik D, Kelly-Hayes M, Kiel DP, Launer LJ, Marciante KD, Massaro JM, Miljkovic I, Nalls MA, Hernandez D, Psaty BM, Rivadeneira F, Rotter J, Seshadri S, Smith AV, Taylor KD, Tiemeier H, Uh HW, Uitterlinden AG, Vaupel JW, Walston J, Westendorp RG, Harris TB, Lumley T, van Duijn CM, Murabito JM. A meta-analysis of four genome-wide association studies of survival to age 90 years or older: the Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci. 2010 May; 65(5):478-87.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Massaro, Joseph
Lunetta, Kathryn
Kelly-Hayes, Margaret
Glazer, Nicole
D'Agostino, Ralph
Seshadri, Sudha

PMID: 20304771; PMCID: PMC2854887; DOI: 10.1093/gerona/glq028;

Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar; 42(3):240-4.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Glazer, Nicole
Ramachandran, Vasan

PMID: 20173747; PMCID: PMC2871387; DOI: 10.1038/ng.537;

Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, Sotoodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Ellinor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet. 2010 Feb; 42(2):153-9.View Related Profiles.

Benjamin, Emelia
Magnani, Jared
Lunetta, Kathryn
Larson, Martin
Ramachandran, Vasan

PMID: 20062060; PMCID: PMC2850197; DOI: 10.1038/ng.517;

Peloso GM, Timofeev N, Lunetta KL. Principal-component-based population structure adjustment in the North American Rheumatoid Arthritis Consortium data: impact of single-nucleotide polymorphism set and analysis method. BMC Proc. 2009; 3 Suppl 7:S108.View Related Profiles.

Peloso, Gina
Lunetta, Kathryn

PMID: 20017972; PMCID: PMC2795879; DOI: 10.1186/1753-6561-3-s7-s108;

Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N, Köttgen A, van Duijn CM, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009 Aug; 41(8):879-81.View Related Profiles.

Benjamin, Emelia
Lunetta, Kathryn
Larson, Martin
Wolf, Philip
D'Agostino, Ralph
Ramachandran, Vasan

PMID: 19597492; PMCID: PMC2761746; DOI: 10.1038/ng.416;

Hendricks AE, Latourelle JC, Lunetta KL, Cupples LA, Wheeler V, MacDonald ME, Gusella JF, Myers RH. Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington disease gene from male carriers of high normal alleles (27-35 CAG). Am J Med Genet A. 2009 Jul; 149A(7):1375-81.View Related Profiles.

Latourelle, Jeanne
Lunetta, Kathryn
Cupples, L
Myers, Richard

PMID: 19507258; PMCID: PMC2724761; DOI: 10.1002/ajmg.a.32901;

Perry JR, Stolk L, Franceschini N, Lunetta KL, Zhai G, McArdle PF, Smith AV, Aspelund T, Bandinelli S, Boerwinkle E, Cherkas L, Eiriksdottir G, Estrada K, Ferrucci L, Folsom AR, Garcia M, Gudnason V, Hofman A, Karasik D, Kiel DP, Launer LJ, van Meurs J, Nalls MA, Rivadeneira F, Shuldiner AR, Singleton A, Soranzo N, Tanaka T, Visser JA, Weedon MN, Wilson SG, Zhuang V, Streeten EA, Harris TB, Murray A, Spector TD, Demerath EW, Uitterlinden AG, Murabito JM. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet. 2009 Jun; 41(6):648-50.View Related Profiles.

Murabito, Joanne
Lunetta, Kathryn

PMID: 19448620; PMCID: PMC2942986; DOI: 10.1038/ng.386;

Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen MH, Zhao Z, Yamamoto JF, Meigs JB, Nicaud V, Perret C, Zeller T, Blankenberg S, Tiret L, Keaney JF, Vasan RS, Benjamin EJ. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circ Cardiovasc Genet. 2009 Jun; 2(3):229-37.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin
Chen, Ming-Huei
Ramachandran, Vasan

PMID: 20031590; PMCID: PMC2897047; DOI: 10.1161/CIRCGENETICS.108.804245;

Cuenco KT, Friedland R, Baldwin CT, Guo J, Vardarajan B, Lunetta KL, Cupples LA, Green RC, DeCarli C, Farrer LA. Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families. Neurobiol Aging. 2011 Feb; 32(2):249-56.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 19328595; PMCID: PMC2930090; DOI: 10.1016/j.neurobiolaging.2009.02.014;

Meng YA, Yu Y, Cupples LA, Farrer LA, Lunetta KL. Performance of random forest when SNPs are in linkage disequilibrium. BMC Bioinformatics. 2009; 10:78.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 19265542; PMCID: PMC2666661; DOI: 10.1186/1471-2105-10-78;

Psaty BM, O'Donnell CJ, Gudnason V, Lunetta KL, Folsom AR, Rotter JI, Uitterlinden AG, Harris TB, Witteman JC, Boerwinkle E. Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium: Design of prospective meta-analyses of genome-wide association studies from 5 cohorts. Circ Cardiovasc Genet. 2009 Feb; 2(1):73-80.View Related Profiles.

O'Donnell, Christopher
Lunetta, Kathryn

PMID: 20031568; PMCID: PMC2875693; DOI: 10.1161/CIRCGENETICS.108.829747;

Kääb S, Darbar D, van Noord C, Dupuis J, Pfeufer A, Newton-Cheh C, Schnabel R, Makino S, Sinner MF, Kannankeril PJ, Beckmann BM, Choudry S, Donahue BS, Heeringa J, Perz S, Lunetta KL, Larson MG, Levy D, MacRae CA, Ruskin JN, Wacker A, Schömig A, Wichmann HE, Steinbeck G, Meitinger T, Uitterlinden AG, Witteman JC, Roden DM, Benjamin EJ, Ellinor PT. Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation. Eur Heart J. 2009 Apr; 30(7):813-9.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin

PMID: 19141561; PMCID: PMC2663727; DOI: 10.1093/eurheartj/ehn578;

Guo CY, Lunetta KL, DeStefano AL, Cupples LA. Combined haplotype relative risk (CHRR): a general and simple genetic association test that combines trios and unrelated case-controls. Genet Epidemiol. 2009 Jan; 33(1):54-62.View Related Profiles.

DeStefano, Anita
Lunetta, Kathryn
Cupples, L

PMID: 18636528; PMCID: PMC2700841; DOI: 10.1002/gepi.20356;

Perneczky R, Wagenpfeil S, Lunetta KL, Cupples LA, Green RC, DeCarli C, Farrer LA, Kurz A. Education attenuates the effect of medial temporal lobe atrophy on cognitive function in Alzheimer's disease: the MIRAGE study. J Alzheimers Dis. 2009; 17(4):855-62.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 19542606; PMCID: PMC2868929; DOI: 10.3233/JAD-2009-1117;

Kathiresan S, Willer CJ, Peloso GM, Demissie S, Musunuru K, Schadt EE, Kaplan L, Bennett D, Li Y, Tanaka T, Voight BF, Bonnycastle LL, Jackson AU, Crawford G, Surti A, Guiducci C, Burtt NP, Parish S, Clarke R, Zelenika D, Kubalanza KA, Morken MA, Scott LJ, Stringham HM, Galan P, Swift AJ, Kuusisto J, Bergman RN, Sundvall J, Laakso M, Ferrucci L, Scheet P, Sanna S, Uda M, Yang Q, Lunetta KL, Dupuis J, de Bakker PI, O'Donnell CJ, Chambers JC, Kooner JS, Hercberg S, Meneton P, Lakatta EG, Scuteri A, Schlessinger D, Tuomilehto J, Collins FS, Groop L, Altshuler D, Collins R, Lathrop GM, Melander O, Salomaa V, Peltonen L, Orho-Melander M, Ordovas JM, Boehnke M, Abecasis GR, Mohlke KL, Cupples LA. Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet. 2009 Jan; 41(1):56-65.View Related Profiles.

O'Donnell, Christopher
Peloso, Gina
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Yang, Qiong
Demissie, Serkalem

PMID: 19060906; PMCID: PMC2881676; DOI: 10.1038/ng.291;

T Cuenco K, Lunetta KL, Baldwin CT, McKee AC, Guo J, Cupples LA, Green RC, St George-Hyslop PH, Chui H, DeCarli C, Farrer LA. Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease. Arch Neurol. 2008 Dec; 65(12):1640-8.View Related Profiles.

McKee, Ann
Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 19064752; PMCID: PMC2719762; DOI: 10.1001/archneur.65.12.1640;

Schnabel R, Dupuis J, Larson MG, Lunetta KL, Robins SJ, Zhu Y, Rong J, Yin X, Stirnadel HA, Nelson JJ, Wilson PW, Keaney JF, Vasan RS, Benjamin EJ. Clinical and genetic factors associated with lipoprotein-associated phospholipase A2 in the Framingham Heart Study. Atherosclerosis. 2009 Jun; 204(2):601-7.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin
Robins, Sander
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 19135199; PMCID: PMC2893025; DOI: 10.1016/j.atherosclerosis.2008.10.030;

Dragileva E, Hendricks A, Teed A, Gillis T, Lopez ET, Friedberg EC, Kucherlapati R, Edelmann W, Lunetta KL, MacDonald ME, Wheeler VC. Intergenerational and striatal CAG repeat instability in Huntington's disease knock-in mice involve different DNA repair genes. Neurobiol Dis. 2009 Jan; 33(1):37-47. PMID: 18930147; PMCID: PMC2811282; DOI: 10.1016/j.nbd.2008.09.014;

Lash TL, Pedersen L, Cronin-Fenton D, Ahern TP, Rosenberg CL, Lunetta KL, Silliman RA, Hamilton-Dutoit S, Garne JP, Ewertz M, Sørensen HT. Tamoxifen's protection against breast cancer recurrence is not reduced by concurrent use of the SSRI citalopram. Br J Cancer. 2008 Aug 19; 99(4):616-21.View Related Profiles.

Sorensen, Henrik
Lunetta, Kathryn
Silliman, Rebecca

PMID: 18665165; PMCID: PMC2527838; DOI: 10.1038/sj.bjc.6604533;

Lunetta KL. Genetic association studies. Circulation. 2008 Jul 1; 118(1):96-101. PMID: 18591452; DOI: 10.1161/CIRCULATIONAHA.107.700401;

Cuenco KT, Green RC, Zhang J, Lunetta K, Erlich PM, Cupples LA, Farrer LA, DeCarli C. Magnetic resonance imaging traits in siblings discordant for Alzheimer disease. J Neuroimaging. 2008 Jul; 18(3):268-75.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 18808654; PMCID: PMC2778266; DOI: 10.1111/j.1552-6569.2007.00191.x;

Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, Yin X, Rong J, Vita JA, Newton-Cheh C, Levy D, Keaney JF, Vasan RS, Mitchell GF, Benjamin EJ. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension. 2008 Jun; 51(6):1651-7.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Vita, Joseph
Lunetta, Kathryn
Larson, Martin
Ramachandran, Vasan
Yin, Xiaoyan

PMID: 18426996; PMCID: PMC2892983; DOI: 10.1161/HYPERTENSIONAHA.107.105668;

Peloso GM, Dupuis J, Hirschhorn JN, Lunetta KL. Genetic Epidemiology. A Principal Components Approach to Adjust for Population Structure using Family Data. 2008.

Meng Y, Yang Q, Cuenco KT, Cupples LA, Destefano AL, Lunetta KL. Two-stage approach for identifying single-nucleotide polymorphisms associated with rheumatoid arthritis using random forests and Bayesian networks. BMC Proc. 2007; 1 Suppl 1:S56.View Related Profiles.

DeStefano, Anita
Lunetta, Kathryn
Cupples, L
Yang, Qiong

PMID: 18466556; PMCID: PMC2367609; DOI: 10.1186/1753-6561-1-s1-s56;

Lee DS, Larson MG, Lunetta KL, Dupuis J, Rong J, Keaney JF, Lipinska I, Baldwin CT, Vasan RS, Benjamin EJ. Clinical and genetic correlates of soluble P-selectin in the community. J Thromb Haemost. 2008 Jan; 6(1):20-31.View Related Profiles.

Baldwin, Clinton
Benjamin, Emelia
Dupuis, Josee
Lunetta, Kathryn
Larson, Martin
Ramachandran, Vasan

PMID: 17944986

Benjamin EJ, Dupuis J, Larson MG, Lunetta KL, Booth SL, Govindaraju DR, Kathiresan S, Keaney JF, Keyes MJ, Lin JP, Meigs JB, Robins SJ, Rong J, Schnabel R, Vita JA, Wang TJ, Wilson PW, Wolf PA, Vasan RS. Genome-wide association with select biomarker traits in the Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S11.View Related Profiles.

Benjamin, Emelia
Dupuis, Josee
Vita, Joseph
Lunetta, Kathryn
Larson, Martin
Wolf, Philip
Robins, Sander
Ramachandran, Vasan

PMID: 17903293; PMCID: PMC1995615; DOI: 10.1186/1471-2350-8-S1-S11;

Lunetta KL, D'Agostino RB, Karasik D, Benjamin EJ, Guo CY, Govindaraju R, Kiel DP, Kelly-Hayes M, Massaro JM, Pencina MJ, Seshadri S, Murabito JM. Genetic correlates of longevity and selected age-related phenotypes: a genome-wide association study in the Framingham Study. BMC Med Genet. 2007; 8 Suppl 1:S13.View Related Profiles.

Benjamin, Emelia
Murabito, Joanne
Massaro, Joseph
Lunetta, Kathryn
Kelly-Hayes, Margaret
Pencina, Michael
D'Agostino, Ralph
Seshadri, Sudha

PMID: 17903295; PMCID: PMC1995604; DOI: 10.1186/1471-2350-8-S1-S13;

Kiel DP, Demissie S, Dupuis J, Lunetta KL, Murabito JM, Karasik D. Genome-wide association with bone mass and geometry in the Framingham Heart Study. BMC Med Genet. 2007; 8 Suppl 1:S14.View Related Profiles.

Murabito, Joanne
Dupuis, Josee
Lunetta, Kathryn
Demissie, Serkalem

PMID: 17903296; PMCID: PMC1995606; DOI: 10.1186/1471-2350-8-S1-S14;

Lunetta KL, Erlich PM, Cuenco KT, Cupples LA, Green RC, Farrer LA, Decarli C. Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study. Alzheimer Dis Assoc Disord. 2007 Apr-Jun; 21(2):85-91.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 17545732

Guo CY, Lunetta KL, DeStefano AL, Ordovas JM, Cupples LA. Informative-transmission disequilibrium test (i-TDT): combined linkage and association mapping that includes unaffected offspring as well as affected offspring. Genet Epidemiol. 2007 Feb; 31(2):115-33.View Related Profiles.

DeStefano, Anita
Lunetta, Kathryn
Cupples, L

PMID: 17123304

Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, Wakutani Y, Cupples LA, Cuenco KT, Green RC, Pinessi L, Rainero I, Sorbi S, Bruni A, Duara R, Friedland RP, Inzelberg R, Hampe W, Bujo H, Song YQ, Andersen OM, Willnow TE, Graff-Radford N, Petersen RC, Dickson D, Der SD, Fraser PE, Schmitt-Ulms G, Younkin S, Mayeux R, Farrer LA, St George-Hyslop P. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet. 2007 Feb; 39(2):168-77.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 17220890; PMCID: PMC2657343; DOI: 10.1038/ng1943;

Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007; 8 Suppl 1:S1.View Related Profiles.

DeStefano, Anita
O'Donnell, Christopher
Liu, Chunyu
Benjamin, Emelia
O'Connor, George
Murabito, Joanne
Dupuis, Josee
Lunetta, Kathryn
Cupples, L
Larson, Martin
Heard-Costa, Nancy
Wolf, Philip
Yang, Qiong
D'Agostino, Ralph
Demissie, Serkalem
Hwang, Shih-Jen
Seshadri, Sudha
Ramachandran, Vasan

PMID: 17903291; PMCID: PMC1995613; DOI: 10.1186/1471-2350-8-S1-S1;

Akomolafe A, Lunetta KL, Erlich PM, Cupples LA, Baldwin CT, Huyck M, Green RC, Farrer LA. Genetic association between endothelial nitric oxide synthase and Alzheimer disease. Clin Genet. 2006 Jul; 70(1):49-56.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Farrer, Lindsay

PMID: 16813604

Shearman AM, Cooper JA, Kotwinski PJ, Miller GJ, Humphries SE, Ardlie KG, Jordan B, Irenze K, Lunetta KL, Schuit SC, Uitterlinden AG, Pols HA, Demissie S, Cupples LA, Mendelsohn ME, Levy D, Housman DE. Estrogen receptor alpha gene variation is associated with risk of myocardial infarction in more than seven thousand men from five cohorts. Circ Res. 2006 Mar 17; 98(5):590-2.View Related Profiles.

Lunetta, Kathryn
Cupples, L
Demissie, Serkalem

PMID: 16484614

Erlich PM, Lunetta KL, Cupples LA, Huyck M, Green RC, Baldwin CT, Farrer LA. Polymorphisms in the PON gene cluster are associated with Alzheimer disease. Hum Mol Genet. 2006 Jan 1; 15(1):77-85.View Related Profiles.

Baldwin, Clinton
Lunetta, Kathryn
Cupples, L
Farrer, Lindsay

PMID: 16319130

Campbell CD, Ogburn EL, Lunetta KL, Lyon HN, Freedman ML, Groop LC, Altshuler D, Ardlie KG, Hirschhorn JN. Demonstrating stratification in a European American population. Nat Genet. 2005 Aug; 37(8):868-72. PMID: 16041375

Guo CY, DeStefano AL, Lunetta KL, Dupuis J, Cupples LA. Expectation maximization algorithm based haplotype relative risk (EM-HRR): test of linkage disequilibrium using incomplete case-parents trios. Hum Hered. 2005; 59(3):125-35.View Related Profiles.

DeStefano, Anita
Dupuis, Josee
Lunetta, Kathryn
Cupples, L

PMID: 15867473

Bureau A, Dupuis J, Falls K, Lunetta KL, Hayward B, Keith TP, Van Eerdewegh P. Identifying SNPs predictive of phenotype using random forests. Genet Epidemiol. 2005 Feb; 28(2):171-82.View Related Profiles.

Dupuis, Josee
Lunetta, Kathryn

PMID: 15593090

Lunetta KL, Hayward LB, Segal J, Van Eerdewegh P. Screening large-scale association study data: exploiting interactions using random forests. BMC Genet. 2004; 5:32. PMID: 15588316; PMCID: PMC545646

Ardlie KG, Lunetta KL, Seielstad M. Testing for population subdivision and association in four case-control studies. Am J Hum Genet. 2002 Aug; 71(2):304-11. PMID: 12096349; PMCID: PMC379163

Robins JM, Smoller JW, Lunetta KL. On the validity of the TDT test in the presence of comorbidity and ascertainment bias. Genet Epidemiol. 2001 Dec; 21(4):326-36. PMID: 11754468

Krop IE, Sgroi D, Porter DA, Lunetta KL, LeVangie R, Seth P, Kaelin CM, Rhei E, Bosenberg M, Schnitt S, Marks JR, Pagon Z, Belina D, Razumovic J, Polyak K. HIN-1, a putative cytokine highly expressed in normal but not cancerous mammary epithelial cells. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9796-801. PMID: 11481438; PMCID: PMC55532

Wallace SR, Oken MM, Lunetta KL, Panoskaltsis-Mortari A, Masellis AM. Abnormalities of bone marrow mesenchymal cells in multiple myeloma patients. Cancer. 2001 Apr 1; 91(7):1219-30. PMID: 11283920

Bandipalliam P, Lunetta KL, Syngal S. Meta-analysis of genotype-phenotype correlations in Familial Adenomatous Polyposis. Gastroenterology. 2001; 120(5). View Publication
Wang Z, Niu T, Lunetta KL, Xu X, Fang Z, Xu X. Observation of null alleles of microsatellite markers in a Chinese population. GeneScreen. 2001; 1(1):41-45. View Publication

Seth P, Lunetta KL, Bell DW, Gray H, Nasser SM, Rhei E, Kaelin CM, Iglehart DJ, Marks JR, Garber JE, Haber DA, Polyak K. Phenol sulfotransferases: hormonal regulation, polymorphism, and age of onset of breast cancer. Cancer Res. 2000 Dec 15; 60(24):6859-63. PMID: 11156380

Smoller JW, Lunetta KL, Robins J. Implications of comorbidity and ascertainment bias for identifying disease genes. Am J Med Genet. 2000 Dec 4; 96(6):817-22. PMID: 11121189

Yeh JJ, Lunetta KL, van Orsouw NJ, Moore FD, Mutter GL, Vijg J, Dahia PL, Eng C. Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours. Oncogene. 2000 Apr 13; 19(16):2060-6. PMID: 10803467

Lunetta KL, Faraone SV, Biederman J, Laird NM. Family-based tests of association and linkage that use unaffected sibs, covariates, and interactions. Am J Hum Genet. 2000 Feb; 66(2):605-14. PMID: 10677320; PMCID: PMC1288113

Smoller JW, Lunetta KL, Robins J. The impact of spurious comorbidity and ascertainment bias on genetic association studies. American Journal of Medical Genetics. 2000; 96(4):487.

Marsh DJ, Kum JB, Lunetta KL, Bennett MJ, Gorlin RJ, Ahmed SF, Bodurtha J, Crowe C, Curtis MA, Dasouki M, Dunn T, Feit H, Geraghty MT, Graham JM, Hodgson SV, Hunter A, Korf BR, Manchester D, Miesfeldt S, Murday VA, Nathanson KL, Parisi M, Pober B, Romano C, Eng C, et al. PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome. Hum Mol Genet. 1999 Aug; 8(8):1461-72. PMID: 10400993

Wilcox MA, Smoller JW, Lunetta KL, Neuberg D. Using recursive partitioning for exploration and follow-up of linkage and association analyses. Genet Epidemiol. 1999; 17 Suppl 1:S391-6. PMID: 10597468

Lunetta KL, Wilcox M, Smoller J, Neuberg D. Exploring linkage for alcoholism using affection status and quantitative event related potential phenotypes. Genet Epidemiol. 1999; 17 Suppl 1:S241-6. PMID: 10597443

Marsh DJ, Coulon V, Lunetta KL, Rocca-Serra P, Dahia PL, Zheng Z, Liaw D, Caron S, Duboué B, Lin AY, Richardson AL, Bonnetblanc JM, Bressieux JM, Cabarrot-Moreau A, Chompret A, Demange L, Eeles RA, Yahanda AM, Fearon ER, Fricker JP, Gorlin RJ, Hodgson SV, Huson S, Lacombe D, Eng C, et al. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum Mol Genet. 1998 Mar; 7(3):507-15. PMID: 9467011

Lunetta KL, Rogus JJ. Strategy for mapping minor histocompatibility genes involved in graft-versus-host disease: a novel application of discordant sib pair methodology. Genet Epidemiol. 1998; 15(6):595-607. PMID: 9811421

Marsh DJ, Roth S, Lunetta KL, Hemminki A, Dahia PL, Sistonen P, Zheng Z, Caron S, van Orsouw NJ, Bodmer WF, Cottrell SE, Dunlop MG, Eccles D, Hodgson SV, Järvinen H, Kellokumpu I, Markie D, Neale K, Phillips R, Rozen P, Syngal S, Vijg J, Tomlinson IP, Aaltonen LA, Eng C. Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome. Cancer Res. 1997 Nov 15; 57(22):5017-21. PMID: 9371495

Larson GP, Zhang G, Ding S, Foldenauer K, Udar N, Gatti RA, Neuberg D, Lunetta KL, Ruckdeschel JC, Longmate J, Flanagan S, Krontiris TG. An allelic variant at the ATM locus is implicated in breast cancer susceptibility. Genet Test. 1997-1998; 1(3):165-70. PMID: 10464642

Nichols WC, Antin JH, Lunetta KL, Terry VH, Hertel CE, Wheatley MA, Arnold ND, Siemieniak DR, Boehnke M, Ginsburg D. Polymorphism of adhesion molecule CD31 is not a significant risk factor for graft-versus-host disease. Blood. 1996 Dec 15; 88(12):4429-34. PMID: 8977234

Lunetta KL, Boehnke M, Lange K, Cox DR. Selected locus and multiple panel models for radiation hybrid mapping. Am J Hum Genet. 1996 Sep; 59(3):717-25. PMID: 8751873; PMCID: PMC1914929

Hou YC, Richards JE, Bingham EL, Pawar H, Scott K, Segal M, Lunetta KL, Boehnke M, Sieving PA. Linkage study of Best's vitelliform macular dystrophy (VMD2) in a large North American family. Hum Hered. 1996 Jul-Aug; 46(4):211-20. PMID: 8807324

Lunetta KL, Boehnke M, Lange K, Cox DR. Experimental design and error detection for polyploid radiation hybrid mapping. Genome Res. 1995 Sep; 5(2):151-63. PMID: 9132269

Lange K, Boehnke M, Cox DR, Lunetta KL. Statistical methods for polyploid radiation hybrid mapping. Genome Res. 1995 Sep; 5(2):136-50. PMID: 9132268

Pawar H, Bingham EL, Lunetta KL, Segal M, Richards JE, Boehnke M, Sieving PA. Refined genetic mapping of juvenile X-linked retinoschisis. Hum Hered. 1995 Jul-Aug; 45(4):206-10. PMID: 7558052

Lunetta KL, Boehnke M. Multipoint radiation hybrid mapping: comparison of methods, sample size requirements, and optimal study characteristics. Genomics. 1994 May 1; 21(1):92-103. PMID: 8088821

Price RA, Lunetta K, Ness R, Charles MA, Saad MF, Ravussin E, Bennett PH, Pettitt DJ, Knowler WC. Obesity in Pima Indians. Distribution characteristics and possible thresholds for genetic studies. Int J Obes Relat Metab Disord. 1992 Nov; 16(11):851-7. PMID: 1337339

Boehnke M, Lunetta KL, Hauser E, Van der Stoep JL et. al. RHMAP: Statistical Package for Multipoint Radiation Hybrid Mapping. 1992.

Vuchetich JP, Dunnette J, Lunetta KL, Weinshilboum RM, Price RA. Inheritance of human plasma dopamine-beta-hydroxylase thermal stability. Genet Epidemiol. 1991; 8(4):237-51. PMID: 1756947

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 310 publications over 32 distinct years, with a maximum of 27 publications in 2017

Bar chart showing 310 publications over 32 distinct years, with a maximum of 27 publications in 2017

Year	Publications
1991	1
1992	2
1994	1
1995	3
1996	3
1997	2
1998	2
1999	3
2000	5
2001	5
2002	1
2004	1
2005	4
2006	2
2007	9
2008	9
2009	11
2010	12
2011	16
2012	14
2013	17
2014	18
2015	17
2016	22
2017	27
2018	16
2019	19
2020	9
2021	19
2022	18
2023	19
2024	3

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Statistical genetics
Genetic Epidemiology
Healthy Aging
Atrial Fibrillation
Alzheimer's Disease

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