Orian S. Shirihai, MD, PhD
Adjunct Associate Professor
Boston University School of Medicine
Dept of Medicine

MD, Technion - Israel Institute of Technology
PhD, Technion - Israel Institute of Technology

Expertise includes: Mitochondial biology; Mitochondrial bioenergetics; Mitochondrial dynamics; Imaging of mitochondrial architecture and function; Microscopy.

Graduate Faculty (Primary Mentor of Grad Students)
Boston University School of Medicine, Division of Graduate Medical Sciences

Boston Medical Center

Yr Title Project-Sub Proj Pubs
2018 Mitochondrial regulation of energy efficiency 5R01DK099618-05 1
2017 Mitochondrial regulation of energy efficiency 7R01DK099618-04 1
2016 Mitochondrial regulation of energy efficiency 5R01DK099618-03 1
2015 Mitochondrial regulation of energy efficiency 5R01DK099618-02 1
2015 Mitochondrial dynamics in beta cell function and dysfunction 5R01DK074778-10 38
2015 Metabolic Signal Transduction in Adipocytes 5R01DK056690-15 38
2014 Mitochondrial regulation of energy efficiency 1R01DK099618-01A1 1
2014 Mitochondrial dynamics in beta cell function and dysfunction 5R01DK074778-09 38
2014 Metabolic Signal Transduction in Adipocytes 5R01DK056690-14 38
2013 Mitochondrial dynamics in beta cell function and dysfunction 5R01DK074778-08 38
Showing 10 of 41 results. Show All Results
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Taddeo EP, Stiles L, Sereda S, Ritou E, Wolf DM, Abdullah M, Swanson Z, Wilhelm J, Bellin M, McDonald P, Caradonna K, Neilson A, Liesa M, Shirihai OS. Individual islet respirometry reveals functional diversity within the islet population of mice and human donors. Mol Metab. 2018 Jul 25. PMID: 30098928.
  2. Xu S, Catapang A, Braas D, Stiles L, Doh HM, Lee JT, Graeber TG, Damoiseaux R, Shirihai O, Herschman HR. A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers. Cancer Metab. 2018; 6:7. PMID: 29988332.
  3. Liesa M, Shirihai OS. Mitochondrial adaptation in obesity is a ClpPicated business. EMBO Rep. 2018 Jun; 19(6). PMID: 29789387.
  4. Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A. Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J. 2018 May 15; 37(10).View Related Profiles. PMID: 29632021.
  5. Benador IY, Veliova M, Mahdaviani K, Petcherski A, Wikstrom JD, Assali EA, Acín-Pérez R, Shum M, Oliveira MF, Cinti S, Sztalryd C, Barshop WD, Wohlschlegel JA, Corkey BE, Liesa M, Shirihai OS. Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion. Cell Metab. 2018 Apr 03; 27(4):869-885.e6.View Related Profiles. PMID: 29617645.
  6. Zhou Z, Ribas V, Rajbhandari P, Drew BG, Moore TM, Fluitt AH, Reddish BR, Whitney KA, Georgia S, Vergnes L, Reue K, Liesa M, Shirihai O, van der Bliek AM, Chi NW, Mahata SK, Tiano JP, Hewitt SC, Tontonoz P, Korach KS, Mauvais-Jarvis F, Hevener AL. Estrogen receptor a protects pancreatic ß-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress. J Biol Chem. 2018 Mar 30; 293(13):4735-4751. PMID: 29378845.
  7. Alsabeeh N, Chausse B, Kakimoto PA, Kowaltowski AJ, Shirihai O. Cell culture models of fatty acid overload: Problems and solutions. Biochim Biophys Acta. 2018 02; 1863(2):143-151.View Related Profiles. PMID: 29155055.
  8. Montemurro C, Vadrevu S, Gurlo T, Butler AE, Vongbunyong KE, Petcherski A, Shirihai OS, Satin LS, Braas D, Butler PC, Tudzarova S. Cell cycle-related metabolism and mitochondrial dynamics in a replication-competent pancreatic beta-cell line. Cell Cycle. 2017; 16(21):2086-2099. PMID: 28820316.
  9. Tkatch T, Greotti E, Baranauskas G, Pendin D, Roy S, Nita LI, Wettmarshausen J, Prigge M, Yizhar O, Shirihai OS, Fishman D, Hershfinkel M, Fleidervish IA, Perocchi F, Pozzan T, Sekler I. Optogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsins. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):E5167-E5176. PMID: 28611221.
  10. Mahdaviani K, Benador IY, Su S, Gharakhanian RA, Stiles L, Trudeau KM, Cardamone M, Enríquez-Zarralanga V, Ritou E, Aprahamian T, Oliveira MF, Corkey BE, Perissi V, Liesa M, Shirihai OS. Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis. EMBO Rep. 2017 Jul; 18(7):1123-1138.View Related Profiles. PMID: 28539390.
Showing 10 of 109 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 109 publications over 20 distinct years, with a maximum of 15 publications in 2012

In addition to these self-described keywords below, a list of MeSH based concepts is available here.

Contact for Mentoring:

650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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