Fuzhong Qin, MD, PhD
Research Associate Professor
Boston University School of Medicine
Dept of Medicine
Cardiovascular Medicine

MD, Datong Medical College
PhD, Shanxi Medical University



I have a broad background in cardiovascular physiology, with specific training and expertise in the areas of reactive oxygen species and myocardial remodeling in pacing-induced heart failure, myocardial infarction-induced heart failure, pressure overload-induced myocardial hypertrophy and failure and transgenic mice with heart failure as well as reactive oxygen species in cultured cardiac myocytes. Particularly I have expertise (scientific) in a) oxidative stress, myocyte apoptosis, and apoptosis-related signal transduction pathways, b) oxidative stress, oxidative protein modifications of SERCA2, intracellular calcium transients and myocyte contractile function, c) oxidative stress, myocyte hypertrophy and myocardial diastolic dysfunction. I also have expertise (technical) in the animal models (mice, rats, rabbits and dogs) of myocardial ischemia / reperfusion, coronary artery ligation-induced myocardial infarction and failure, and ascending aortic constriction-induced myocardial hypertrophy and failure, conventional echocardiography, mitral inflow and tissue Doppler echocardiography, in vivo hemodynamics, ex vivo Langendorff isolated heart perfusion, measurements of intracellular calcium concentration and contractile function in isolated myocytes, myocyte culture, assessment of oxidative stress, histological measurements including hematoxylin and eosin staining, Masson trichrome staining, TUNEL staining and immunohistochemical and immunofluorescence staining, biochemical measurements including Western blot, immunoprecipitation, RT-PCR and etc.

Boston Medical Center


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

  1. Ho JE, Rahban Y, Sandhu H, Hiremath PG, Ayalon N, Qin F, Perez AJ, Downing J, Gopal DM, Cheng S, Colucci WS. Preclinical Alterations in Myocardial Microstructure in People with Metabolic Syndrome. Obesity (Silver Spring). 2017 Sep; 25(9):1516-1522.View Related Profiles. PMID: 28737258; DOI: 10.1002/oby.21936;.
  2. Xu XJ, Babo E, Qin F, Croteau D, Colucci WS. Short-term caloric restriction in db/db mice improves myocardial function and increases high molecular weight (HMW) adiponectin. IJC Metab Endocr. 2016 Dec; 13:28-34.View Related Profiles. PMID: 27942464.
  3. Sverdlov AL, Elezaby A, Qin F, Behring JB, Luptak I, Calamaras TD, Siwik DA, Miller EJ, Liesa M, Shirihai OS, Pimentel DR, Cohen RA, Bachschmid MM, Colucci WS. Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet-Induced Metabolic Heart Disease. J Am Heart Assoc. 2016 Jan 11; 5(1).View Related Profiles. PMID: 26755553; PMCID: PMC4859372; DOI: 10.1161/JAHA.115.002555;.
  4. Miller EJ, Calamaras T, Elezaby A, Sverdlov A, Qin F, Luptak I, Wang K, Sun X, Vijay A, Croteau D, Bachschmid M, Cohen RA, Walsh K, Colucci WS. Partial Liver Kinase B1 (LKB1) Deficiency Promotes Diastolic Dysfunction, De Novo Systolic Dysfunction, Apoptosis, and Mitochondrial Dysfunction With Dietary Metabolic Challenge. J Am Heart Assoc. 2015 Dec 31; 5(1).View Related Profiles. PMID: 26722122; PMCID: PMC4859355; DOI: 10.1161/JAHA.115.002277;.
  5. Elezaby A, Sverdlov AL, Tu VH, Soni K, Luptak I, Qin F, Liesa M, Shirihai OS, Rimer J, Schaffer JE, Wilson S C, Edward J M. Mitochondrial remodeling in mice with cardiomyocyte-specific lipid overload. J Mol Cell Cardiol. 2015 Feb; 79:275-83.View Related Profiles. PMID: 25497302; PMCID: PMC4301992; DOI: 10.1016/j.yjmcc.2014.12.001;.
  6. Qin F, Siwik DA, Pimentel DR, Morgan RJ, Biolo A, Tu VH, Kang YJ, Cohen RA, Colucci WS. Cytosolic H2O2 mediates hypertrophy, apoptosis, and decreased SERCA activity in mice with chronic hemodynamic overload. Am J Physiol Heart Circ Physiol. 2014 May 15; 306(10):H1453-63.View Related Profiles. PMID: 24633550; PMCID: PMC4024717; DOI: 10.1152/ajpheart.00084.2014;.
  7. Qin F, Siwik DA, Lancel S, Zhang J, Kuster GM, Luptak I, Wang L, Tong X, Kang YJ, Cohen RA, Colucci WS. Hydrogen peroxide-mediated SERCA cysteine 674 oxidation contributes to impaired cardiac myocyte relaxation in senescent mouse heart. J Am Heart Assoc. 2013 Aug; 2(4):e000184.View Related Profiles. PMID: 23963753; PMCID: PMC3828801; DOI: 10.1161/JAHA.113.000184;.
  8. Metes-Kosik N, Luptak I, Dibello PM, Handy DE, Tang SS, Zhi H, Qin F, Jacobsen DW, Loscalzo J, Joseph J. Both selenium deficiency and modest selenium supplementation lead to myocardial fibrosis in mice via effects on redox-methylation balance. Mol Nutr Food Res. 2012 Dec; 56(12):1812-24.View Related Profiles. PMID: 23097236; PMCID: PMC3546539; DOI: 10.1002/mnfr.201200386;.
  9. Qin F, Siwik DA, Luptak I, Hou X, Wang L, Higuchi A, Weisbrod RM, Ouchi N, Tu VH, Calamaras TD, Miller EJ, Verbeuren TJ, Walsh K, Cohen RA, Colucci WS. The polyphenols resveratrol and S17834 prevent the structural and functional sequelae of diet-induced metabolic heart disease in mice. Circulation. 2012 Apr 10; 125(14):1757-64, S1-6.View Related Profiles. PMID: 22388319; PMCID: PMC3354628; DOI: 10.1161/CIRCULATIONAHA.111.067801;.
  10. Mazzini M, Tadros T, Siwik D, Joseph L, Bristow M, Qin F, Cohen R, Monahan K, Klein M, Colucci W. Primary carnitine deficiency and sudden death: in vivo evidence of myocardial lipid peroxidation and sulfonylation of sarcoendoplasmic reticulum calcium ATPase 2. Cardiology. 2011; 120(1):52-8.View Related Profiles. PMID: 22116472; DOI: 10.1159/000333127;.
Showing 10 of 25 results. Show More

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

Bar chart showing 25 publications over 15 distinct years, with a maximum of 4 publications in 2004

YearPublications
20021
20032
20044
20051
20061
20071
20093
20101
20112
20122
20131
20142
20151
20162
20171
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650 Albany St Evans Biomed Research Ctr
Boston MA 02118
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