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PhD, University of Oklahoma
MS, Zhejiang University

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Endocrinology, Diabetes & Nutrition Faculty

Research
Publications

BMC Research
NIH RePORTER Research

Metabolic Signal Transduction in Adipocytes
04/01/2011 - 01/31/2016 (Activity-level PI)
PI: Barbara E. Corkey, PhD
NIH-NIDDK
5R01 DK056690-13

Healthy Aging and Myostatin Antagonsits
04/01/2011 - 03/31/2013 (PI)
NIH-NIA
5R21 AG037859-02

Guo Pilot - Boston OAIC: A Translational Approach to Function Promoting Anabolic Therapies
09/30/2009 - 05/31/2011 (PI)
NIH-NIA
5 P30 AG031679-03

Lipid Metabolism in Fat Cells
02/01/2006 - 12/31/2010 (PI)
NIH-NIDDK
5 R01 DK059261-09

Lipid Metabolism In Fat Cells
06/01/2000 - 01/31/2006 (PI)
NIH-NIDDK
5 R01 DK59261-04 & 04S1 (A)

Title

Yr	Title	Project-Sub Proj	Pubs
2014	Metabolic Signal Transduction in Adipocytes	5R01DK056690-14	64
2013	Metabolic Signal Transduction in Adipocytes	5R01DK056690-13	64
2012	Healthy Aging and Myostatin Antagonsits	5R21AG037859-02	11
2012	Metabolic Signal Transduction in Adipocytes	5R01DK056690-12	64
2011	Healthy Aging and Myostatin Antagonsits	1R21AG037859-01A1	11
2011	Metabolic Signal Transduction in Adipocytes	2R01DK056690-11	64
2010	Lipid Metabolism in Fat Cells	5R01DK059261-09	25
2009	Lipid Metabolism in Fat Cells	5R01DK059261-08	25
2008	Lipid Metabolism in Fat Cells	5R01DK059261-07	25
2007	Lipid Metabolism in Fat Cells	5R01DK059261-06	25

Showing 10 of 16 results. Show All Results

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.

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Guo W, Wong S, Bhasin S. AAV-mediated administration of myostatin pro-peptide mutant in adult Ldlr null mice reduces diet-induced hepatosteatosis and arteriosclerosis. PLoS One. 2013; 8(8):e71017.View Related Profiles.

Bhasin, Shalender
Guo, Wen

PMID: 23936482; PMCID: PMC3731267; DOI: 10.1371/journal.pone.0071017;

Guo W, Bachman E, Li M, Roy CN, Blusztajn J, Wong S, Chan SY, Serra C, Jasuja R, Travison TG, Muckenthaler MU, Nemeth E, Bhasin S. Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 2013 Apr; 12(2):280-91.View Related Profiles.

Bhasin, Shalender
Travison, Thomas
Guo, Wen

PMID: 23399021; PMCID: PMC3602280; DOI: 10.1111/acel.12052;

Guo W, Wong S, Li M, Liang W, Liesa M, Serra C, Jasuja R, Bartke A, Kirkland JL, Shirihai O, Bhasin S. Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male mice. PLoS One. 2012; 7(12):e51180.View Related Profiles.

Liesa Roig, Marc
Shirihai, Orian
Bhasin, Shalender
Guo, Wen

PMID: 23240002; PMCID: PMC3519841; DOI: 10.1371/journal.pone.0051180;

Guo W, Li Y, Liang W, Wong S, Apovian C, Kirkland JL, Corkey BE. Beta-mecaptoethanol suppresses inflammation and induces adipogenic differentiation in 3T3-F442A murine preadipocytes. PLoS One. 2012; 7(7):e40958.View Related Profiles.

Corkey, Barbara
Apovian, Caroline
Guo, Wen

PMID: 22911724; PMCID: PMC3402440; DOI: 10.1371/journal.pone.0040958;

Toraldo G, Bhasin S, Bakhit M, Guo W, Serra C, Safer JD, Bhawan J, Jasuja R. Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking ß-catenin nuclear translocation and cross-talk with TGF-ß signaling in keratinocytes. Wound Repair Regen. 2012 Jan-Feb; 20(1):61-73.View Related Profiles.

Toraldo, Gianluca
Bhawan, Jag
Safer, Joshua
Bhasin, Shalender
Guo, Wen

PMID: 22276587; PMCID: PMC5461922; DOI: 10.1111/j.1524-475X.2011.00757.x;

Trudeau K, Roy S, Guo W, Hernández C, Villarroel M, Simó R, Roy S. Fenofibric acid reduces fibronectin and collagen type IV overexpression in human retinal pigment epithelial cells grown in conditions mimicking the diabetic milieu: functional implications in retinal permeability. Invest Ophthalmol Vis Sci. 2011 Aug; 52(9):6348-54.View Related Profiles.

Trudeau, Kyle
Roy, Sayon
Guo, Wen

PMID: 21715349; PMCID: PMC3175988; DOI: 10.1167/iovs.11-7282;

Bhasin S, Jasuja R, Tu P, Storer TW, Guo W. Novel strategies for improving physical function. Horm Res Paediatr. 2011; 76 Suppl 1:17-23.View Related Profiles.

Jasuja, Ravi
Bhasin, Shalender
Guo, Wen

PMID: 21778743; DOI: 10.1159/000329148;

Trudeau K, Molina AJ, Guo W, Roy S. High glucose disrupts mitochondrial morphology in retinal endothelial cells: implications for diabetic retinopathy. Am J Pathol. 2010 Jul; 177(1):447-55.View Related Profiles.

Molina, Anthony J.A.
Trudeau, Kyle
Roy, Sayon
Guo, Wen

PMID: 20522647; PMCID: PMC2893686; DOI: 10.2353/ajpath.2010.091029;

Luo Z, Zang M, Guo W. AMPK as a metabolic tumor suppressor: control of metabolism and cell growth. Future Oncol. 2010 Mar; 6(3):457-70.View Related Profiles.

Zang, Mengwei
Guo, Wen
Luo, Zhijun

PMID: 20222801; PMCID: PMC2854547; DOI: 10.2217/fon.09.174;

Tao R, Gong J, Luo X, Zang M, Guo W, Wen R, Luo Z. AMPK exerts dual regulatory effects on the PI3K pathway. J Mol Signal. 2010; 5(1):1.View Related Profiles.

Zang, Mengwei
Guo, Wen
Luo, Zhijun

PMID: 20167101; PMCID: PMC2848036; DOI: 10.1186/1750-2187-5-1;

Showing 10 of 37 results. Show More

Wang T, Si Y, Shirihai OS, Si H, Schultz V, Corkey RF, Hu L, Deeney JT, Guo W, Corkey BE. Respiration in adipocytes is inhibited by reactive oxygen species. Obesity (Silver Spring). 2010 Aug; 18(8):1493-502.View Related Profiles.

Corkey, Barbara
Deeney, Jude
Shirihai, Orian
Guo, Wen

PMID: 20035277; PMCID: PMC6154476; DOI: 10.1038/oby.2009.456;

Guo W, Wong S, Pudney J, Jasuja R, Hua N, Jiang L, Miller A, Hruz PW, Hamilton JA, Bhasin S. Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir. Arterioscler Thromb Vasc Biol. 2009 Dec; 29(12):2028-32.View Related Profiles.

Hamilton, James
Pudney, Jeffrey
Hua, Ning
Bhasin, Shalender
Guo, Wen

PMID: 19762785; PMCID: PMC2783673; DOI: 10.1161/ATVBAHA.109.191304;

Tu P, Bhasin S, Hruz PW, Herbst KL, Castellani LW, Hua N, Hamilton JA, Guo W. Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice. Diabetes. 2009 Aug; 58(8):1739-48.View Related Profiles.

Hamilton, James
Hua, Ning
Bhasin, Shalender
Guo, Wen

PMID: 19509018; PMCID: PMC2712781; DOI: 10.2337/db09-0349;

Guo W, Jiang L, Bhasin S, Khan SM, Swerdlow RH. DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination. Mitochondrion. 2009 Jul; 9(4):261-5.View Related Profiles.

Bhasin, Shalender
Guo, Wen

PMID: 19324101; PMCID: PMC2798162; DOI: 10.1016/j.mito.2009.03.003;

Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, Choong K, Tchkonia T, Lebrasseur NK, Flanagan JN, Hamilton JA, Viereck JC, Narula NS, Kirkland JL, Jasuja R. Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Mol Cell Endocrinol. 2008 Dec 16; 296(1-2):32-40.View Related Profiles.

Hamilton, James
Bhasin, Shalender
Guo, Wen

PMID: 18801408; PMCID: PMC2873614; DOI: 10.1016/j.mce.2008.08.019;

Guo W, Flanagan J, Jasuja R, Kirkland J, Jiang L, Bhasin S. The effects of myostatin on adipogenic differentiation of human bone marrow-derived mesenchymal stem cells are mediated through cross-communication between Smad3 and Wnt/beta-catenin signaling pathways. J Biol Chem. 2008 Apr 4; 283(14):9136-45.View Related Profiles.

Bhasin, Shalender
Guo, Wen

PMID: 18203713; PMCID: PMC2431017; DOI: 10.1074/jbc.M708968200;

Han JR, Deng B, Sun J, Chen CG, Corkey BE, Kirkland JL, Ma J, Guo W. Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects. Metabolism. 2007 Jul; 56(7):985-91.View Related Profiles.

Corkey, Barbara
Guo, Wen

PMID: 17570262

Guo W, Bigornia S, Leizerman I, Xie W, McDonnell M, Clemente K, Pirtskhalava T, Kirkland JL, Gokce N, Corkey BE, Sullivan LM, Apovian CM. New scanning electron microscopic method for determination of adipocyte size in humans and mice. Obesity (Silver Spring). 2007 Jul; 15(7):1657-65.View Related Profiles.

Corkey, Barbara
Apovian, Caroline
Sullivan, Lisa
McDonnell, Marie
Gokce, Noyan
Guo, Wen

PMID: 17636083

Guo W, Pirtskhalava T, Tchkonia T, Xie W, Thomou T, Han J, Wang T, Wong S, Cartwright A, Hegardt FG, Corkey BE, Kirkland JL. Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity. Am J Physiol Endocrinol Metab. 2007 Apr; 292(4):E1041-51.View Related Profiles.

Corkey, Barbara
Guo, Wen

PMID: 17148751

Guo W, Xie W, Han J. Modulation of adipocyte lipogenesis by octanoate: involvement of reactive oxygen species. Nutr Metab (Lond). 2006; 3:30. PMID: 16872526; PMCID: PMC1550392

Xie W, Hamilton JA, Kirkland JL, Corkey BE, Guo W. Oleate-induced formation of fat cells with impaired insulin sensitivity. Lipids. 2006 Mar; 41(3):267-71.View Related Profiles.

Corkey, Barbara
Hamilton, James
Guo, Wen

PMID: 16711601

Guo W, Huang N, Cai J, Xie W, Hamilton JA. Fatty acid transport and metabolism in HepG2 cells. Am J Physiol Gastrointest Liver Physiol. 2006 Mar; 290(3):G528-34.View Related Profiles.

Hamilton, James
Huang, Nasi
Guo, Wen

PMID: 16254047

Zang Y, Wang T, Xie W, Wang-Fischer YL, Getty L, Han J, Corkey BE, Guo W. Regulation of acetyl CoA carboxylase and carnitine palmitoyl transferase-1 in rat adipocytes. Obes Res. 2005 Sep; 13(9):1530-9.View Related Profiles.

Corkey, Barbara
Guo, Wen

PMID: 16222055

Hu L, Deeney JT, Nolan CJ, Peyot ML, Ao A, Richard AM, Luc E, Faergeman NJ, Knudsen J, Guo W, Sorhede-Winzell M, Prentki M, Corkey BE. Regulation of lipolytic activity by long-chain acyl-coenzyme A in islets and adipocytes. Am J Physiol Endocrinol Metab. 2005 Dec; 289(6):E1085-92.View Related Profiles.

Corkey, Barbara
Deeney, Jude
Guo, Wen

PMID: 16091387

Guo W, Xie W, Lei T, Hamilton JA. Eicosapentaenoic acid, but not oleic acid, stimulates beta-oxidation in adipocytes. Lipids. 2005 Aug; 40(8):815-21.View Related Profiles.

Hamilton, James
Guo, Wen

PMID: 16296400

Wang YL, Guo W, Zang Y, Yaney GC, Vallega G, Getty-Kaushik L, Pilch P, Kandror K, Corkey BE. Acyl coenzyme a synthetase regulation: putative role in long-chain acyl coenzyme a partitioning. Obes Res. 2004 Nov; 12(11):1781-8.View Related Profiles.

Corkey, Barbara
Kandror, Konstantin
Pilch, Paul
Guo, Wen

PMID: 15601973

Lei T, Xie W, Han J, Corkey BE, Hamilton JA, Guo W. Medium-chain Fatty acids attenuate agonist-stimulated lipolysis, mimicking the effects of starvation. Obes Res. 2004 Apr; 12(4):599-611.View Related Profiles.

Corkey, Barbara
Hamilton, James
Guo, Wen

PMID: 15090627

Fisette PL, Ram S, Andersen JM, Guo W, Ingalls RR. The Lip lipoprotein from Neisseria gonorrhoeae stimulates cytokine release and NF-kappaB activation in epithelial cells in a Toll-like receptor 2-dependent manner. J Biol Chem. 2003 Nov 21; 278(47):46252-60.View Related Profiles.

Ingalls, Robin
Guo, Wen

PMID: 12966099

Guo W, Lei T, Wang T, Corkey BE, Han J. Octanoate inhibits triglyceride synthesis in 3T3-L1 and human adipocytes. J Nutr. 2003 Aug; 133(8):2512-8.View Related Profiles.

Corkey, Barbara
Guo, Wen

PMID: 12888629

Wang T, Zang Y, Ling W, Corkey BE, Guo W. Metabolic partitioning of endogenous fatty acid in adipocytes. Obes Res. 2003 Jul; 11(7):880-7.View Related Profiles.

Corkey, Barbara
Guo, Wen

PMID: 12855758

Han J, Hamilton JA, Kirkland JL, Corkey BE, Guo W. Medium-chain oil reduces fat mass and down-regulates expression of adipogenic genes in rats. Obes Res. 2003 Jun; 11(6):734-44.View Related Profiles.

Corkey, Barbara
Hamilton, James
Guo, Wen

PMID: 12805394

Kamp F, Guo W, Souto R, Pilch PF, Corkey BE, Hamilton JA. Rapid flip-flop of oleic acid across the plasma membrane of adipocytes. J Biol Chem. 2003 Mar 7; 278(10):7988-95.View Related Profiles.

Corkey, Barbara
Hamilton, James
Pilch, Paul
Guo, Wen

PMID: 12499383

Hamilton JA, Guo W, Kamp F. Mechanism of cellular uptake of long-chain fatty acids: Do we need cellular proteins? Mol Cell Biochem. 2002 Oct; 239(1-2):17-23.View Related Profiles.

Hamilton, James
Guo, Wen

PMID: 12479564

Guo W, Kurze V, Huber T, Afdhal NH, Beyer K, Hamilton JA. A solid-state NMR study of phospholipid-cholesterol interactions: sphingomyelin-cholesterol binary systems. Biophys J. 2002 Sep; 83(3):1465-78.View Related Profiles.

Hamilton, James
Guo, Wen

PMID: 12202372; PMCID: PMC1302245

Tchkonia T, Giorgadze N, Pirtskhalava T, Tchoukalova Y, Karagiannides I, Forse RA, DePonte M, Stevenson M, Guo W, Han J, Waloga G, Lash TL, Jensen MD, Kirkland JL. Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes. Am J Physiol Regul Integr Comp Physiol. 2002 May; 282(5):R1286-96. PMID: 11959668

Han J, Farmer SR, Kirkland JL, Corkey BE, Yoon R, Pirtskhalava T, Ido Y, Guo W. Octanoate attenuates adipogenesis in 3T3-L1 preadipocytes. J Nutr. 2002 May; 132(5):904-10.View Related Profiles.

Corkey, Barbara
Farmer, Stephen
Guo, Wen
Ido, Yasuo

PMID: 11983812

Wang Y, Han J, Zang Y, Guo W. Effects of vanadate on leptin production from isolated rat adipocytes. Biol Trace Elem Res. 2002 Feb; 85(2):171-82. PMID: 11899024

This graph shows the total number of publications by year, by first, middle/unknown, or last author.

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